4GQLA

Crystal structure of the catalytic domain of human mmp12 in complex with selective phosphinic inhibitor rxp470.1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 41
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4gqlA00
1EAKA 3AIGA 2W13A 1MMBA 3LIRA 1FBLA 5D1SA 2FV5A 1C3IA 5L7FA 3LQBA 5JMYA 2TCLA 1CAQA 1G49A 2W12A 1SMPA 3K7NA 1QUAA 4J4MA 3K7LA 3DWBA 1YQYA 1IAAA 3O64A 3LE9A 5D2BA 4GUYA 4JIJA 4FXQA 5CUHA 2POJA 3LK8A 1Y0VA 4H82A 1KUHA 2PJTA 3TS4A 1ZXVA 3EHYA 1KAPP 3LIKA 4ON1A 4R3VA 1HOVA 1CXVA 4H76A 1JK3A 3EDZA 4PKQA 3EWJA 1FM1A 3ZUKA 3E8RA 1B3DA 5LABA 3KRYA 3WV2A 1JAPA 3LJZA 1OS2A 4I03A 4WF6A 1XUDA 3KEKA 1Z3JA 3DPEA 3G42A 1IACA 1MMQA 2Y6CA 1R1HA 1MNCA 4XBHA 3F17A 1SLNA 4G0DA 3N2VA 2DDFA 4JQGA 3DSLA 1BUDA 3CKIA 1BQOA 2DW1A 1Y8JA 2JT5A 4H30A 4DV8A 5I0LA 3HBUP 1AKLA 1JKYA 2W14A 5CZMA 1D8MA 4GQLA 1ROSA 1OMJA 5D7WA 2MZEA 1ASTA 4XM8A 3F1AA 4FU4A 2CKIA 1QICA 1JAOA 1C8TA 4EFSA 1KUIA 2O3EA 1YOUA 2MZIA 3RTSA 4WK7A 4FXYP 3ELMA 4WKEA 3G5CA 5D1TA 2QPJA 3I7GA 1GKDA 1MMRA 1KBCA 1BM6A 5I43A 2OW9A 1G12A 1MMPA 1G4KA 4GWMA 3KMCA 1ND1A 1CGEA 2ERQA 3P1VA 1ATLA 2X7MA 3SHIA 2OXZA 5L79A 1UMSA 3EHXA 4CTHA 3LJTA 3DNGA 1G05A 1ZXCA 3WV3A 1R1IA 3F16A 1I1IP 1HFSA 1D8FA 3HDAP 1DTHA 3AYUA 1R1JA 1PWPA 1FLSA 3ZVSA 3USNA 2D1OA 4GR8A 4H1QA 1K7IA 3OHOA 2SRTA 2OY4A 3HBVP 2USNA 2Y6DA 4L19A 2OY2A 1G9KA 2DDYA 1HY7A 4H2EA 2E3XA 1IABA 1DMTA 2JSDA 5B5PA 2W15A 966CA 5I3MA 4XM6A 1XUCA 2FV9A 1AF0A 4IN9A 1OM6A 3F19A 3LEAA 2RJPA 2OI0A 5D3CA 5BPAA 1GO8P 4FVLA 1OO9A 2YB9A 1BKCE 1UTTA 1QIBA 1PWVA 1CK7A 3B2ZA 1XFZA 1CGLA 5I12A 1IAGA 1GKCA 4H84A 1IADA 1K7GA 1UMTA 3EDHA 3LKAA 4DPEA 1OM8A 4JA1A 1SRPA 3O2XA 1GO7P 2OW0A 4GR0A 2X3CA 4DF9A 4ZR5A 3KEJA 2RJQA 3DL1A 3TSKA 1BKCI 3LGPA 2V4BA 1OM7A 3UVCA 3LUMA 1QJIA 3LILA 1JANA 1OS9A 1BUVM 3TVCA 1YP1A 1XFXA 1C7KA 3U1RA 4WKIA 1L6JA 2OXWA 1A85A 3EDGA 3HDBA 4JPAA 3LJGA 2O36A 2W0DA 5CXAA 1GE5A 1RMZA 3N2UA 4PKUA 4I35A 3Q2HA 1Y93A 2K2GA 1USNA 1BZSA 1K7QA 2OW1A 4PKWA 4Q1LA 5I4OA 3Q2GA 3HYGA 1YCMA 2L0RA 4G9LA 1XFWA 1JH1A 4L6TA 2I47A 3BA0A 5BOTA 3KMEA 1HTDA 3AYKA 3L0VA 4DD8A 2WO9A 1PWQA 1R55A 2MLRA 1ZS0A 3DPFA 3LUNA 2JT6A 5D1UA 5BOYA 2XS4A 1SU3A 1B8YA 2ERPA 4AYKA 1BKCA 1KUGA 1AYKA 3WV1A 3KWVC 1XFUA 2AYKA 2CLTA 2OVXA 2JNPA 2X3BA 3GBOA 1BSWA 1I76A 1JIWP 2D1NA 1XFYA 1JJ9A 2DW2A 1R54A 2OVZA 3NX7A 1J7NA 1KUFA 3HY7A 1PWWA 2EROA 3LQ0A 456CA 1XFVA 4WZVA 1UEAA 4GR3A 4H3XA 2WO8A 1CIZA 1GXDA 2WOAA 4A3WA 4A7BA 1BIWA 1O0QA 1JIZA 3KECA 2X3AA 1XURA 1HFCA 2OZRA 4AXQA 3F15A 3TT4A 3RTTA 4PKRA 4XCTA 1ZVXA 4QKZA 1BQQM 1ZP5A 5H8XA 3MA2A 3VTGA 4GWNA 4HX3A 1D7XA 1S4BP 4H49A 1HV5A 3ZXHA 3F18A 2AIGP 1A86A 1KUKA 1O0TA 4XM7A 1SATA 1QJJA 5B5OA 2XS3A 3B8ZA 1JAQA 2DW0A 1GE6A 3P24A 3L0TA 1CGFA 2YIGA 3V96B 4AIGA 1WNIA 4IUWA 4IJOA 4GF1A 2HU6A 4JP4A 2J83A 1EUBA 3EDIA 1GE7A 1QIAA 1RM8A 2MLSA 1Q3AA 3KHIA 1H71P 3B92A 3LMCA 5I2ZA 1I73A 3HY9A 1PWUA 3HB2P 1ZTQA 3OHLA 2J0TA 4PKTA 1D5JA 2N8RA 1EB6A 1UTZA 830CA 4HMAA 4L63A 3VI1A 2JIHA 4PKSA 2E2DA 2A8HA 4ILWD 2MZHA 2K9CA 2Z2DA 1SLMA 4PKVA 2KRJA 2OXUA 4AUOA 1IAEA 1CQRA 3I7IA 2OW2A
chains in the Genus database with same CATH superfamily
1EAKA 3AIGA 2W13A 1MMBA 3LIRA 1FBLA 5D1SA 2FV5A 1C3IA 5L7FA 3LQBA 5JMYA 2TCLA 1CAQA 1G49A 2W12A 1SMPA 3K7NA 1QUAA 4J4MA 3K7LA 3DWBA 1YQYA 1IAAA 3O64A 3LE9A 5D2BA 4GUYA 4JIJA 4FXQA 5CUHA 2POJA 3LK8A 1Y0VA 4H82A 1KUHA 2PJTA 3TS4A 1ZXVA 3EHYA 1KAPP 3LIKA 4ON1A 4R3VA 1HOVA 1CXVA 4H76A 1JK3A 3EDZA 4PKQA 3EWJA 1FM1A 3ZUKA 3E8RA 1B3DA 5LABA 3KRYA 3WV2A 1JAPA 3LJZA 1OS2A 4I03A 4WF6A 1XUDA 3KEKA 1Z3JA 3DPEA 3G42A 1IACA 1MMQA 2Y6CA 1R1HA 1MNCA 4XBHA 3DTKA 3F17A 1SLNA 4G0DA 3N2VA 2DDFA 4JQGA 3DSLA 1BUDA 3CKIA 1BQOA 2DW1A 1Y8JA 2JT5A 4H30A 4DV8A 5I0LA 3HBUP 1AKLA 1JKYA 2W14A 5CZMA 1D8MA 4GQLA 1ROSA 1OMJA 5D7WA 2MZEA 1ASTA 4XM8A 3F1AA 4FU4A 2CKIA 1QICA 1JAOA 1C8TA 3DTIA 4EFSA 1KUIA 2O3EA 1YOUA 2MZIA 3RTSA 4WK7A 4FXYP 3ELMA 4WKEA 3G5CA 5D1TA 2QPJA 3I7GA 1GKDA 1MMRA 1KBCA 1BM6A 5I43A 2OW9A 1G12A 1MMPA 1G4KA 4GWMA 3KMCA 1ND1A 1CGEA 2ERQA 3P1VA 1ATLA 2X7MA 3SHIA 2OXZA 5L79A 1UMSA 3EHXA 4CTHA 3LJTA 3DNGA 1G05A 1ZXCA 3WV3A 1R1IA 3F16A 1I1IP 1HFSA 1D8FA 3HDAP 1DTHA 3AYUA 1R1JA 1PWPA 1FLSA 3ZVSA 3USNA 2D1OA 4GR8A 4H1QA 1K7IA 3OHOA 1TVIA 2OY4A 2SRTA 2USNA 2Y6DA 3HBVP 2OY2A 4L19A 1G9KA 2DDYA 1HY7A 4H2EA 2E3XA 2YUFA 1IABA 1DMTA 2JSDA 5B5PA 2W15A 966CA 5I3MA 4XM6A 1XUCA 2FV9A 1AF0A 4IN9A 1OM6A 3F19A 3LEAA 2RJPA 2OI0A 5D3CA 5BPAA 1GO8P 4FVLA 1OO9A 2YB9A 1OZ9A 1BKCE 1UTTA 1QIBA 1PWVA 1CK7A 3B2ZA 1XFZA 1CGLA 5I12A 1IAGA 1GKCA 4H84A 1IADA 1K7GA 1UMTA 3EDHA 3LKAA 4DPEA 1OM8A 4JA1A 1SRPA 3O2XA 1GO7P 2OW0A 4GR0A 2X3CA 4DF9A 4ZR5A 3KEJA 2RJQA 3DL1A 3TSKA 1BKCI 3LGPA 2V4BA 1OM7A 3UVCA 3LUMA 1QJIA 3LILA 1JANA 1OS9A 1BUVM 3TVCA 1YP1A 1XFXA 1C7KA 3U1RA 4WKIA 1L6JA 2OXWA 1A85A 3EDGA 3HDBA 4JPAA 3LJGA 2O36A 2W0DA 5CXAA 1GE5A 1RMZA 3N2UA 4PKUA 4I35A 3Q2HA 1Y93A 2K2GA 1USNA 1BZSA 1K7QA 2OW1A 4PKWA 4Q1LA 5I4OA 3Q2GA 3HYGA 1YCMA 2L0RA 4G9LA 1XFWA 1JH1A 4L6TA 2I47A 3BA0A 5BOTA 3KMEA 1HTDA 3AYKA 3L0VA 1XAXA 4DD8A 2WO9A 1PWQA 1R55A 2MLRA 1ZS0A 3DPFA 3LUNA 2JT6A 5D1UA 5BOYA 3DTEA 2XS4A 1SU3A 1B8YA 2ERPA 4AYKA 1BKCA 1KUGA 1AYKA 3WV1A 3KWVC 1XFUA 2AYKA 2CLTA 2OVXA 2JNPA 2X3BA 1XM5A 3GBOA 1BSWA 1I76A 1JIWP 2D1NA 1XFYA 1JJ9A 2DW2A 1R54A 2OVZA 3NX7A 1J7NA 1KUFA 3HY7A 1PWWA 2EROA 3LQ0A 456CA 1XFVA 4WZVA 1UEAA 4GR3A 4H3XA 2WO8A 1CIZA 1GXDA 2WOAA 4A3WA 4A7BA 1BIWA 1O0QA 1JIZA 3KECA 2X3AA 1XURA 1HFCA 2OZRA 4AXQA 3F15A 3TT4A 3RTTA 4PKRA 4XCTA 1ZVXA 4QKZA 1BQQM 1ZP5A 5H8XA 3MA2A 3VTGA 4GWNA 4HX3A 1D7XA 1S4BP 4H49A 1HV5A 3ZXHA 3F18A 2AIGP 1A86A 1KUKA 1O0TA 4XM7A 1SATA 1QJJA 5B5OA 2XS3A 3B8ZA 1JAQA 2DW0A 1GE6A 3P24A 3L0TA 1CGFA 2YIGA 3V96B 4AIGA 1WNIA 4IUWA 4IJOA 4GF1A 2HU6A 4JP4A 4L7AA 2J83A 1EUBA 3EDIA 1GE7A 1QIAA 1RM8A 2MLSA 1Q3AA 3KHIA 1H71P 3B92A 3LMCA 5I2ZA 1I73A 3HY9A 1PWUA 3HB2P 1ZTQA 3OHLA 2J0TA 4PKTA 1D5JA 2N8RA 1EB6A 1UTZA 830CA 4HMAA 4L63A 3VI1A 2JIHA 4PKSA 2E2DA 2A8HA 4ILWD 2MZHA 2K9CA 2Z2DA 1SLMA 4PKVA 2KRJA 2OXUA 4AUOA 1IAEA 1CQRA 3I7IA 2OW2A
chains in the Genus database with same CATH topology
1EAKA 3AIGA 2W13A 1MMBA 3LIRA 1FBLA 5D1SA 2FV5A 1C3IA 5L7FA 3LQBA 5JMYA 2TCLA 1CAQA 1G49A 2W12A 1SMPA 3K7NA 1QUAA 4J4MA 3K7LA 3DWBA 1YQYA 1IAAA 3O64A 3LE9A 5D2BA 4GUYA 4JIJA 4FXQA 5CUHA 2POJA 3LK8A 1Y0VA 4H82A 1KUHA 2PJTA 3TS4A 1ZXVA 3EHYA 1KAPP 3LIKA 4ON1A 4R3VA 1HOVA 1CXVA 4H76A 1JK3A 3EDZA 4PKQA 3EWJA 1FM1A 3ZUKA 3E8RA 1B3DA 5LABA 3KRYA 3WV2A 1JAPA 3LJZA 1OS2A 4I03A 4WF6A 1XUDA 3KEKA 1Z3JA 3DPEA 3G42A 1IACA 1MMQA 2Y6CA 1R1HA 1MNCA 4XBHA 3DTKA 3F17A 1SLNA 4G0DA 3N2VA 2DDFA 4JQGA 3DSLA 1BUDA 3CKIA 1BQOA 2DW1A 1Y8JA 2JT5A 4H30A 4DV8A 5I0LA 3HBUP 1AKLA 1JKYA 2W14A 5CZMA 1D8MA 4GQLA 1ROSA 1OMJA 5D7WA 2MZEA 1ASTA 4XM8A 3F1AA 4FU4A 2CKIA 1QICA 1JAOA 1C8TA 3DTIA 4EFSA 1KUIA 2O3EA 1YOUA 2MZIA 3RTSA 4WK7A 4FXYP 3ELMA 4WKEA 3G5CA 5D1TA 2QPJA 3I7GA 1GKDA 1MMRA 1KBCA 1BM6A 5I43A 2OW9A 1G12A 1MMPA 1G4KA 4GWMA 3KMCA 1ND1A 1CGEA 2ERQA 3P1VA 1ATLA 2X7MA 3SHIA 2OXZA 5L79A 1UMSA 3EHXA 4CTHA 3LJTA 3DNGA 1G05A 1ZXCA 3WV3A 1R1IA 3F16A 1I1IP 1HFSA 1D8FA 3HDAP 1DTHA 3AYUA 1R1JA 1PWPA 1FLSA 3ZVSA 3USNA 2D1OA 4GR8A 4H1QA 1K7IA 3OHOA 2SRTA 2OY4A 3HBVP 2USNA 2Y6DA 4L19A 2OY2A 1G9KA 2DDYA 1HY7A 4H2EA 2E3XA 2YUFA 1IABA 1DMTA 2JSDA 5B5PA 2W15A 966CA 5I3MA 4XM6A 1XUCA 2FV9A 1AF0A 4IN9A 1OM6A 3F19A 3LEAA 2RJPA 2OI0A 5D3CA 5BPAA 1GO8P 4FVLA 1OO9A 2YB9A 1BKCE 1UTTA 1QIBA 1PWVA 1CK7A 3B2ZA 1XFZA 1CGLA 5I12A 1IAGA 1GKCA 4H84A 1IADA 1K7GA 1UMTA 3EDHA 3LKAA 4DPEA 1OM8A 4JA1A 1SRPA 3O2XA 1GO7P 2OW0A 4GR0A 2X3CA 4DF9A 4ZR5A 3KEJA 2RJQA 3DL1A 3TSKA 1BKCI 3LGPA 2V4BA 1OM7A 3UVCA 3LUMA 1QJIA 3LILA 1JANA 1OS9A 1BUVM 3TVCA 1YP1A 1XFXA 1C7KA 3U1RA 4WKIA 1L6JA 2OXWA 1A85A 3EDGA 3HDBA 4JPAA 3LJGA 2O36A 2W0DA 5CXAA 1GE5A 1RMZA 3N2UA 4PKUA 4I35A 3Q2HA 1Y93A 2K2GA 1USNA 1BZSA 1K7QA 2OW1A 4PKWA 4Q1LA 5I4OA 3Q2GA 3HYGA 1YCMA 2L0RA 4G9LA 1XFWA 1JH1A 4L6TA 2I47A 3BA0A 5BOTA 3KMEA 1HTDA 3AYKA 3L0VA 4DD8A 2WO9A 1PWQA 1R55A 2MLRA 1ZS0A 3DPFA 3LUNA 2JT6A 5D1UA 5BOYA 3DTEA 2XS4A 1SU3A 1B8YA 2ERPA 4AYKA 1BKCA 1KUGA 1AYKA 3WV1A 3KWVC 1XFUA 2AYKA 2CLTA 2OVXA 2JNPA 2X3BA 3GBOA 1BSWA 1I76A 1JIWP 2D1NA 1XFYA 1JJ9A 2DW2A 1R54A 2OVZA 3NX7A 1J7NA 1KUFA 3HY7A 1PWWA 2EROA 3LQ0A 456CA 1XFVA 4WZVA 1UEAA 4GR3A 4H3XA 2WO8A 1CIZA 1GXDA 2WOAA 4A3WA 4A7BA 1BIWA 1O0QA 1JIZA 3KECA 2X3AA 1XURA 1HFCA 2OZRA 4AXQA 3F15A 3TT4A 3RTTA 4PKRA 4XCTA 1ZVXA 4QKZA 1BQQM 1ZP5A 5H8XA 3MA2A 3VTGA 4GWNA 4HX3A 1D7XA 1S4BP 4H49A 1HV5A 3ZXHA 3F18A 2AIGP 1A86A 1KUKA 1O0TA 4XM7A 1SATA 1QJJA 5B5OA 2XS3A 3B8ZA 1JAQA 2DW0A 1GE6A 3P24A 3L0TA 1CGFA 2YIGA 3V96B 4AIGA 1WNIA 4IUWA 4IJOA 4GF1A 2HU6A 4JP4A 4L7AA 2J83A 1EUBA 3EDIA 1GE7A 1QIAA 1RM8A 2MLSA 1Q3AA 3KHIA 1H71P 3B92A 3LMCA 5I2ZA 1I73A 3HY9A 1PWUA 3HB2P 1ZTQA 3OHLA 2J0TA 4PKTA 1D5JA 2N8RA 1EB6A 1UTZA 830CA 4HMAA 4L63A 3VI1A 2JIHA 4PKSA 2E2DA 2A8HA 4ILWD 2MZHA 2K9CA 2Z2DA 1SLMA 4PKVA 2KRJA 2OXUA 4AUOA 1IAEA 1CQRA 3I7IA 2OW2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAK A;  3AIG A;  2W13 A;  1MMB A;  3LIR A;  1FBL A;  5D1S A;  2FV5 A;  1C3I A;  5L7F A;  3LQB A;  5JMY A;  2TCL A;  1CAQ A;  1G49 A;  2W12 A;  1SMP A;  3K7N A;  1QUA A;  4J4M A;  3K7L A;  3DWB A;  1YQY A;  1IAA A;  3O64 A;  3LE9 A;  5D2B A;  4GUY A;  4JIJ A;  4FXQ A;  5CUH A;  2POJ A;  3LK8 A;  1Y0V A;  4H82 A;  1KUH A;  2PJT A;  3TS4 A;  1ZXV A;  3EHY A;  1KAP P;  3LIK A;  4ON1 A;  4R3V A;  1HOV A;  1CXV A;  4H76 A;  1JK3 A;  3EDZ A;  4PKQ A;  3EWJ A;  1FM1 A;  3ZUK A;  3E8R A;  1B3D A;  5LAB A;  3KRY A;  3WV2 A;  1JAP A;  3LJZ A;  1OS2 A;  4I03 A;  4WF6 A;  1XUD A;  3KEK A;  1Z3J A;  3DPE A;  3G42 A;  1IAC A;  1MMQ A;  2Y6C A;  1R1H A;  1MNC A;  4XBH A;  3F17 A;  1SLN A;  4G0D A;  3N2V A;  2DDF A;  4JQG A;  3DSL A;  1BUD A;  3CKI A;  1BQO A;  2DW1 A;  1Y8J A;  2JT5 A;  4H30 A;  4DV8 A;  5I0L A;  3HBU P;  1AKL A;  1JKY A;  2W14 A;  5CZM A;  1D8M A;  4GQL A;  1ROS A;  1OMJ A;  5D7W A;  2MZE A;  1AST A;  4XM8 A;  3F1A A;  4FU4 A;  2CKI A;  1QIC A;  1JAO A;  1C8T A;  4EFS A;  1KUI A;  2O3E A;  1YOU A;  2MZI A;  3RTS A;  4WK7 A;  4FXY P;  3ELM A;  4WKE A;  3G5C A;  5D1T A;  2QPJ A;  3I7G A;  1GKD A;  1MMR A;  1KBC A;  1BM6 A;  5I43 A;  2OW9 A;  1G12 A;  1MMP A;  1G4K A;  4GWM A;  3KMC A;  1ND1 A;  1CGE A;  2ERQ A;  3P1V A;  1ATL A;  2X7M A;  3SHI A;  2OXZ A;  5L79 A;  1UMS A;  3EHX A;  4CTH A;  3LJT A;  3DNG A;  1G05 A;  1ZXC A;  3WV3 A;  1R1I A;  3F16 A;  1I1I P;  1HFS A;  1D8F A;  3HDA P;  1DTH A;  3AYU A;  1R1J A;  1PWP A;  1FLS A;  3ZVS A;  3USN A;  2D1O A;  4GR8 A;  4H1Q A;  1K7I A;  3OHO A;  2SRT A;  2OY4 A;  3HBV P;  2USN A;  2Y6D A;  4L19 A;  2OY2 A;  1G9K A;  2DDY A;  1HY7 A;  4H2E A;  2E3X A;  1IAB A;  1DMT A;  2JSD A;  5B5P A;  2W15 A;  966C A;  5I3M A;  4XM6 A;  1XUC A;  2FV9 A;  1AF0 A;  4IN9 A;  1OM6 A;  3F19 A;  3LEA A;  2RJP A;  2OI0 A;  5D3C A;  5BPA A;  1GO8 P;  4FVL A;  1OO9 A;  2YB9 A;  1BKC E;  1UTT A;  1QIB A;  1PWV A;  1CK7 A;  3B2Z A;  1XFZ A;  1CGL A;  5I12 A;  1IAG A;  1GKC A;  4H84 A;  1IAD A;  1K7G A;  1UMT A;  3EDH A;  3LKA A;  4DPE A;  1OM8 A;  4JA1 A;  1SRP A;  3O2X A;  1GO7 P;  2OW0 A;  4GR0 A;  2X3C A;  4DF9 A;  4ZR5 A;  3KEJ A;  2RJQ A;  3DL1 A;  3TSK A;  1BKC I;  3LGP A;  2V4B A;  1OM7 A;  3UVC A;  3LUM A;  1QJI A;  3LIL A;  1JAN A;  1OS9 A;  1BUV M;  3TVC A;  1YP1 A;  1XFX A;  1C7K A;  3U1R A;  4WKI A;  1L6J A;  2OXW A;  1A85 A;  3EDG A;  3HDB A;  4JPA A;  3LJG A;  2O36 A;  2W0D A;  5CXA A;  1GE5 A;  1RMZ A;  3N2U A;  4PKU A;  4I35 A;  3Q2H A;  1Y93 A;  2K2G A;  1USN A;  1BZS A;  1K7Q A;  2OW1 A;  4PKW A;  4Q1L A;  5I4O A;  3Q2G A;  3HYG A;  1YCM A;  2L0R A;  4G9L A;  1XFW A;  1JH1 A;  4L6T A;  2I47 A;  3BA0 A;  5BOT A;  3KME A;  1HTD A;  3AYK A;  3L0V A;  4DD8 A;  2WO9 A;  1PWQ A;  1R55 A;  2MLR A;  1ZS0 A;  3DPF A;  3LUN A;  2JT6 A;  5D1U A;  5BOY A;  2XS4 A;  1SU3 A;  1B8Y A;  2ERP A;  4AYK A;  1BKC A;  1KUG A;  1AYK A;  3WV1 A;  3KWV C;  1XFU A;  2AYK A;  2CLT A;  2OVX A;  2JNP A;  2X3B A;  3GBO A;  1BSW A;  1I76 A;  1JIW P;  2D1N A;  1XFY A;  1JJ9 A;  2DW2 A;  1R54 A;  2OVZ A;  3NX7 A;  1J7N A;  1KUF A;  3HY7 A;  1PWW A;  2ERO A;  3LQ0 A;  456C A;  1XFV A;  4WZV A;  1UEA A;  4GR3 A;  4H3X A;  2WO8 A;  1CIZ A;  1GXD A;  2WOA A;  4A3W A;  4A7B A;  1BIW A;  1O0Q A;  1JIZ A;  3KEC A;  2X3A A;  1XUR A;  1HFC A;  2OZR A;  4AXQ A;  3F15 A;  3TT4 A;  3RTT A;  4PKR A;  4XCT A;  1ZVX A;  4QKZ A;  1BQQ M;  1ZP5 A;  5H8X A;  3MA2 A;  3VTG A;  4GWN A;  4HX3 A;  1D7X A;  1S4B P;  4H49 A;  1HV5 A;  3ZXH A;  3F18 A;  2AIG P;  1A86 A;  1KUK A;  1O0T A;  4XM7 A;  1SAT A;  1QJJ A;  5B5O A;  2XS3 A;  3B8Z A;  1JAQ A;  2DW0 A;  1GE6 A;  3P24 A;  3L0T A;  1CGF A;  2YIG A;  3V96 B;  4AIG A;  1WNI A;  4IUW A;  4IJO A;  4GF1 A;  2HU6 A;  4JP4 A;  2J83 A;  1EUB A;  3EDI A;  1GE7 A;  1QIA A;  1RM8 A;  2MLS A;  1Q3A A;  3KHI A;  1H71 P;  3B92 A;  3LMC A;  5I2Z A;  1I73 A;  3HY9 A;  1PWU A;  3HB2 P;  1ZTQ A;  3OHL A;  2J0T A;  4PKT A;  1D5J A;  2N8R A;  1EB6 A;  1UTZ A;  830C A;  4HMA A;  4L63 A;  3VI1 A;  2JIH A;  4PKS A;  2E2D A;  2A8H A;  4ILW D;  2MZH A;  2K9C A;  2Z2D A;  1SLM A;  4PKV A;  2KRJ A;  2OXU A;  4AUO A;  1IAE A;  1CQR A;  3I7I A;  2OW2 A; 
#chains in the Genus database with same CATH topology
 1EAK A;  3AIG A;  2W13 A;  1MMB A;  3LIR A;  1FBL A;  5D1S A;  2FV5 A;  1C3I A;  5L7F A;  3LQB A;  5JMY A;  2TCL A;  1CAQ A;  1G49 A;  2W12 A;  1SMP A;  3K7N A;  1QUA A;  4J4M A;  3K7L A;  3DWB A;  1YQY A;  1IAA A;  3O64 A;  3LE9 A;  5D2B A;  4GUY A;  4JIJ A;  4FXQ A;  5CUH A;  2POJ A;  3LK8 A;  1Y0V A;  4H82 A;  1KUH A;  2PJT A;  3TS4 A;  1ZXV A;  3EHY A;  1KAP P;  3LIK A;  4ON1 A;  4R3V A;  1HOV A;  1CXV A;  4H76 A;  1JK3 A;  3EDZ A;  4PKQ A;  3EWJ A;  1FM1 A;  3ZUK A;  3E8R A;  1B3D A;  5LAB A;  3KRY A;  3WV2 A;  1JAP A;  3LJZ A;  1OS2 A;  4I03 A;  4WF6 A;  1XUD A;  3KEK A;  1Z3J A;  3DPE A;  3G42 A;  1IAC A;  1MMQ A;  2Y6C A;  1R1H A;  1MNC A;  4XBH A;  3DTK A;  3F17 A;  1SLN A;  4G0D A;  3N2V A;  2DDF A;  4JQG A;  3DSL A;  1BUD A;  3CKI A;  1BQO A;  2DW1 A;  1Y8J A;  2JT5 A;  4H30 A;  4DV8 A;  5I0L A;  3HBU P;  1AKL A;  1JKY A;  2W14 A;  5CZM A;  1D8M A;  4GQL A;  1ROS A;  1OMJ A;  5D7W A;  2MZE A;  1AST A;  4XM8 A;  3F1A A;  4FU4 A;  2CKI A;  1QIC A;  1JAO A;  1C8T A;  3DTI A;  4EFS A;  1KUI A;  2O3E A;  1YOU A;  2MZI A;  3RTS A;  4WK7 A;  4FXY P;  3ELM A;  4WKE A;  3G5C A;  5D1T A;  2QPJ A;  3I7G A;  1GKD A;  1MMR A;  1KBC A;  1BM6 A;  5I43 A;  2OW9 A;  1G12 A;  1MMP A;  1G4K A;  4GWM A;  3KMC A;  1ND1 A;  1CGE A;  2ERQ A;  3P1V A;  1ATL A;  2X7M A;  3SHI A;  2OXZ A;  5L79 A;  1UMS A;  3EHX A;  4CTH A;  3LJT A;  3DNG A;  1G05 A;  1ZXC A;  3WV3 A;  1R1I A;  3F16 A;  1I1I P;  1HFS A;  1D8F A;  3HDA P;  1DTH A;  3AYU A;  1R1J A;  1PWP A;  1FLS A;  3ZVS A;  3USN A;  2D1O A;  4GR8 A;  4H1Q A;  1K7I A;  3OHO A;  1TVI A;  2OY4 A;  2SRT A;  2USN A;  2Y6D A;  3HBV P;  2OY2 A;  4L19 A;  1G9K A;  2DDY A;  1HY7 A;  4H2E A;  2E3X A;  2YUF A;  1IAB A;  1DMT A;  2JSD A;  5B5P A;  2W15 A;  966C A;  5I3M A;  4XM6 A;  1XUC A;  2FV9 A;  1AF0 A;  4IN9 A;  1OM6 A;  3F19 A;  3LEA A;  2RJP A;  2OI0 A;  5D3C A;  5BPA A;  1GO8 P;  4FVL A;  1OO9 A;  2YB9 A;  1OZ9 A;  1BKC E;  1UTT A;  1QIB A;  1PWV A;  1CK7 A;  3B2Z A;  1XFZ A;  1CGL A;  5I12 A;  1IAG A;  1GKC A;  4H84 A;  1IAD A;  1K7G A;  1UMT A;  3EDH A;  3LKA A;  4DPE A;  1OM8 A;  4JA1 A;  1SRP A;  3O2X A;  1GO7 P;  2OW0 A;  4GR0 A;  2X3C A;  4DF9 A;  4ZR5 A;  3KEJ A;  2RJQ A;  3DL1 A;  3TSK A;  1BKC I;  3LGP A;  2V4B A;  1OM7 A;  3UVC A;  3LUM A;  1QJI A;  3LIL A;  1JAN A;  1OS9 A;  1BUV M;  3TVC A;  1YP1 A;  1XFX A;  1C7K A;  3U1R A;  4WKI A;  1L6J A;  2OXW A;  1A85 A;  3EDG A;  3HDB A;  4JPA A;  3LJG A;  2O36 A;  2W0D A;  5CXA A;  1GE5 A;  1RMZ A;  3N2U A;  4PKU A;  4I35 A;  3Q2H A;  1Y93 A;  2K2G A;  1USN A;  1BZS A;  1K7Q A;  2OW1 A;  4PKW A;  4Q1L A;  5I4O A;  3Q2G A;  3HYG A;  1YCM A;  2L0R A;  4G9L A;  1XFW A;  1JH1 A;  4L6T A;  2I47 A;  3BA0 A;  5BOT A;  3KME A;  1HTD A;  3AYK A;  3L0V A;  1XAX A;  4DD8 A;  2WO9 A;  1PWQ A;  1R55 A;  2MLR A;  1ZS0 A;  3DPF A;  3LUN A;  2JT6 A;  5D1U A;  5BOY A;  3DTE A;  2XS4 A;  1SU3 A;  1B8Y A;  2ERP A;  4AYK A;  1BKC A;  1KUG A;  1AYK A;  3WV1 A;  3KWV C;  1XFU A;  2AYK A;  2CLT A;  2OVX A;  2JNP A;  2X3B A;  1XM5 A;  3GBO A;  1BSW A;  1I76 A;  1JIW P;  2D1N A;  1XFY A;  1JJ9 A;  2DW2 A;  1R54 A;  2OVZ A;  3NX7 A;  1J7N A;  1KUF A;  3HY7 A;  1PWW A;  2ERO A;  3LQ0 A;  456C A;  1XFV A;  4WZV A;  1UEA A;  4GR3 A;  4H3X A;  2WO8 A;  1CIZ A;  1GXD A;  2WOA A;  4A3W A;  4A7B A;  1BIW A;  1O0Q A;  1JIZ A;  3KEC A;  2X3A A;  1XUR A;  1HFC A;  2OZR A;  4AXQ A;  3F15 A;  3TT4 A;  3RTT A;  4PKR A;  4XCT A;  1ZVX A;  4QKZ A;  1BQQ M;  1ZP5 A;  5H8X A;  3MA2 A;  3VTG A;  4GWN A;  4HX3 A;  1D7X A;  1S4B P;  4H49 A;  1HV5 A;  3ZXH A;  3F18 A;  2AIG P;  1A86 A;  1KUK A;  1O0T A;  4XM7 A;  1SAT A;  1QJJ A;  5B5O A;  2XS3 A;  3B8Z A;  1JAQ A;  2DW0 A;  1GE6 A;  3P24 A;  3L0T A;  1CGF A;  2YIG A;  3V96 B;  4AIG A;  1WNI A;  4IUW A;  4IJO A;  4GF1 A;  2HU6 A;  4JP4 A;  4L7A A;  2J83 A;  1EUB A;  3EDI A;  1GE7 A;  1QIA A;  1RM8 A;  2MLS A;  1Q3A A;  3KHI A;  1H71 P;  3B92 A;  3LMC A;  5I2Z A;  1I73 A;  3HY9 A;  1PWU A;  3HB2 P;  1ZTQ A;  3OHL A;  2J0T A;  4PKT A;  1D5J A;  2N8R A;  1EB6 A;  1UTZ A;  830C A;  4HMA A;  4L63 A;  3VI1 A;  2JIH A;  4PKS A;  2E2D A;  2A8H A;  4ILW D;  2MZH A;  2K9C A;  2Z2D A;  1SLM A;  4PKV A;  2KRJ A;  2OXU A;  4AUO A;  1IAE A;  1CQR A;  3I7I A;  2OW2 A; 
#chains in the Genus database with same CATH homology
 1EAK A;  3AIG A;  2W13 A;  1MMB A;  3LIR A;  1FBL A;  5D1S A;  2FV5 A;  1C3I A;  5L7F A;  3LQB A;  5JMY A;  2TCL A;  1CAQ A;  1G49 A;  2W12 A;  1SMP A;  3K7N A;  1QUA A;  4J4M A;  3K7L A;  3DWB A;  1YQY A;  1IAA A;  3O64 A;  3LE9 A;  5D2B A;  4GUY A;  4JIJ A;  4FXQ A;  5CUH A;  2POJ A;  3LK8 A;  1Y0V A;  4H82 A;  1KUH A;  2PJT A;  3TS4 A;  1ZXV A;  3EHY A;  1KAP P;  3LIK A;  4ON1 A;  4R3V A;  1HOV A;  1CXV A;  4H76 A;  1JK3 A;  3EDZ A;  4PKQ A;  3EWJ A;  1FM1 A;  3ZUK A;  3E8R A;  1B3D A;  5LAB A;  3KRY A;  3WV2 A;  1JAP A;  3LJZ A;  1OS2 A;  4I03 A;  4WF6 A;  1XUD A;  3KEK A;  1Z3J A;  3DPE A;  3G42 A;  1IAC A;  1MMQ A;  2Y6C A;  1R1H A;  1MNC A;  4XBH A;  3DTK A;  3F17 A;  1SLN A;  4G0D A;  3N2V A;  2DDF A;  4JQG A;  3DSL A;  1BUD A;  3CKI A;  1BQO A;  2DW1 A;  1Y8J A;  2JT5 A;  4H30 A;  4DV8 A;  5I0L A;  3HBU P;  1AKL A;  1JKY A;  2W14 A;  5CZM A;  1D8M A;  4GQL A;  1ROS A;  1OMJ A;  5D7W A;  2MZE A;  1AST A;  4XM8 A;  3F1A A;  4FU4 A;  2CKI A;  1QIC A;  1JAO A;  1C8T A;  3DTI A;  4EFS A;  1KUI A;  2O3E A;  1YOU A;  2MZI A;  3RTS A;  4WK7 A;  4FXY P;  3ELM A;  4WKE A;  3G5C A;  5D1T A;  2QPJ A;  3I7G A;  1GKD A;  1MMR A;  1KBC A;  1BM6 A;  5I43 A;  2OW9 A;  1G12 A;  1MMP A;  1G4K A;  4GWM A;  3KMC A;  1ND1 A;  1CGE A;  2ERQ A;  3P1V A;  1ATL A;  2X7M A;  3SHI A;  2OXZ A;  5L79 A;  1UMS A;  3EHX A;  4CTH A;  3LJT A;  3DNG A;  1G05 A;  1ZXC A;  3WV3 A;  1R1I A;  3F16 A;  1I1I P;  1HFS A;  1D8F A;  3HDA P;  1DTH A;  3AYU A;  1R1J A;  1PWP A;  1FLS A;  3ZVS A;  3USN A;  2D1O A;  4GR8 A;  4H1Q A;  1K7I A;  3OHO A;  2SRT A;  2OY4 A;  3HBV P;  2USN A;  2Y6D A;  4L19 A;  2OY2 A;  1G9K A;  2DDY A;  1HY7 A;  4H2E A;  2E3X A;  2YUF A;  1IAB A;  1DMT A;  2JSD A;  5B5P A;  2W15 A;  966C A;  5I3M A;  4XM6 A;  1XUC A;  2FV9 A;  1AF0 A;  4IN9 A;  1OM6 A;  3F19 A;  3LEA A;  2RJP A;  2OI0 A;  5D3C A;  5BPA A;  1GO8 P;  4FVL A;  1OO9 A;  2YB9 A;  1BKC E;  1UTT A;  1QIB A;  1PWV A;  1CK7 A;  3B2Z A;  1XFZ A;  1CGL A;  5I12 A;  1IAG A;  1GKC A;  4H84 A;  1IAD A;  1K7G A;  1UMT A;  3EDH A;  3LKA A;  4DPE A;  1OM8 A;  4JA1 A;  1SRP A;  3O2X A;  1GO7 P;  2OW0 A;  4GR0 A;  2X3C A;  4DF9 A;  4ZR5 A;  3KEJ A;  2RJQ A;  3DL1 A;  3TSK A;  1BKC I;  3LGP A;  2V4B A;  1OM7 A;  3UVC A;  3LUM A;  1QJI A;  3LIL A;  1JAN A;  1OS9 A;  1BUV M;  3TVC A;  1YP1 A;  1XFX A;  1C7K A;  3U1R A;  4WKI A;  1L6J A;  2OXW A;  1A85 A;  3EDG A;  3HDB A;  4JPA A;  3LJG A;  2O36 A;  2W0D A;  5CXA A;  1GE5 A;  1RMZ A;  3N2U A;  4PKU A;  4I35 A;  3Q2H A;  1Y93 A;  2K2G A;  1USN A;  1BZS A;  1K7Q A;  2OW1 A;  4PKW A;  4Q1L A;  5I4O A;  3Q2G A;  3HYG A;  1YCM A;  2L0R A;  4G9L A;  1XFW A;  1JH1 A;  4L6T A;  2I47 A;  3BA0 A;  5BOT A;  3KME A;  1HTD A;  3AYK A;  3L0V A;  4DD8 A;  2WO9 A;  1PWQ A;  1R55 A;  2MLR A;  1ZS0 A;  3DPF A;  3LUN A;  2JT6 A;  5D1U A;  5BOY A;  3DTE A;  2XS4 A;  1SU3 A;  1B8Y A;  2ERP A;  4AYK A;  1BKC A;  1KUG A;  1AYK A;  3WV1 A;  3KWV C;  1XFU A;  2AYK A;  2CLT A;  2OVX A;  2JNP A;  2X3B A;  3GBO A;  1BSW A;  1I76 A;  1JIW P;  2D1N A;  1XFY A;  1JJ9 A;  2DW2 A;  1R54 A;  2OVZ A;  3NX7 A;  1J7N A;  1KUF A;  3HY7 A;  1PWW A;  2ERO A;  3LQ0 A;  456C A;  1XFV A;  4WZV A;  1UEA A;  4GR3 A;  4H3X A;  2WO8 A;  1CIZ A;  1GXD A;  2WOA A;  4A3W A;  4A7B A;  1BIW A;  1O0Q A;  1JIZ A;  3KEC A;  2X3A A;  1XUR A;  1HFC A;  2OZR A;  4AXQ A;  3F15 A;  3TT4 A;  3RTT A;  4PKR A;  4XCT A;  1ZVX A;  4QKZ A;  1BQQ M;  1ZP5 A;  5H8X A;  3MA2 A;  3VTG A;  4GWN A;  4HX3 A;  1D7X A;  1S4B P;  4H49 A;  1HV5 A;  3ZXH A;  3F18 A;  2AIG P;  1A86 A;  1KUK A;  1O0T A;  4XM7 A;  1SAT A;  1QJJ A;  5B5O A;  2XS3 A;  3B8Z A;  1JAQ A;  2DW0 A;  1GE6 A;  3P24 A;  3L0T A;  1CGF A;  2YIG A;  3V96 B;  4AIG A;  1WNI A;  4IUW A;  4IJO A;  4GF1 A;  2HU6 A;  4JP4 A;  4L7A A;  2J83 A;  1EUB A;  3EDI A;  1GE7 A;  1QIA A;  1RM8 A;  2MLS A;  1Q3A A;  3KHI A;  1H71 P;  3B92 A;  3LMC A;  5I2Z A;  1I73 A;  3HY9 A;  1PWU A;  3HB2 P;  1ZTQ A;  3OHL A;  2J0T A;  4PKT A;  1D5J A;  2N8R A;  1EB6 A;  1UTZ A;  830C A;  4HMA A;  4L63 A;  3VI1 A;  2JIH A;  4PKS A;  2E2D A;  2A8H A;  4ILW D;  2MZH A;  2K9C A;  2Z2D A;  1SLM A;  4PKV A;  2KRJ A;  2OXU A;  4AUO A;  1IAE A;  1CQR A;  3I7I A;  2OW2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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