4GU4A

Crystal structure of the t1l reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
205
structure length
205
Chain Sequence
KIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Viral protein
molecule keywords Outer capsid protein sigma-1
publication title The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
pubmed doi rcsb
source organism Mammalian orthoreovirus 1
total genus 30
structure length 205
sequence length 205
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.20 Mainly Beta Ribbon Laminin reovirus attachment protein sigma1; domain 1 4gu4A01
2.60.90.20 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Virus attachment protein , globular domain 4gu4A02
2OJ5A 2JJLA 2BT8A 4GU3A 2OJ6A 2BT7A 5MHSA 3EOYA 4XC5A 1KKEA 1V1IA 1V1HA 2VRSA 1QIUA 4GU4A 4ODBA 3S6XA 2BSFA
chains in the Genus database with same CATH superfamily
1IGZA 1QFKL 1HAFA 1PTHA 5F19A 3LTFB 4BTTA 3CS7L 3LC5B 1YUGA 4D62A 3FCSB 4E1GA 5KN5C 2P28B 2H9EC 3LIWB 4LMFA 1HX2A 5L2YL 5EGMB 1FSBA 1F0RB 3EGFA 1LMMA 1UZQA 1ATBA 4X8TL 2MGPA 5CKNA 2P3UA 1CX2A 2GD4A 4FM5A 4NG9L 4ZH8B 2NPRA 2HOXA 1IQNL 1V1IA 3LN0A 4D90A 1HRFA 2BT8A 1U67A 2J1KC 4Y7AB 3KQBL 3ELAL 1TPGA 3DEMA 4Y79B 1DVAL 3N0IA 2VVVL 4A7IA 4AQTA 3BQ4A 2P26A 2XBYL 3L89A 1G2LB 3HO5A 2J34B 1KKEA 1F0SB 2Y38A 1L3YA 3LN1A 2PR3B 2J12A 1EAIC 1HT8A 2YGQA 1K37A 4Y76B 3NTBA 3R05A 1IVOC 3NT1A 4RRWA 2WBVA 2VVUL 2J95B 4X8UL 1PGEA 2BZ6L 3QNDA 3HPTA 4CUFA 3KQDL 4MMXB 3BPSE 1EPHA 3KL6B 3N8WA 4K6WA 3NTGA 2Y82B 2P3TA 3N8ZA 1AUTL 2BQWA 4XLWA 3TK5B 3POYA 4CSYA 4Y7BB 1JV2B 4YZUB 5K0HB 2VH6B 1KSNB 1LK9A 3CENL 3GCWE 1W7XL 1I0UA 1LQDA 2XBWL 1HJ7A 2Y5GL 3IITB 3N8YA 4ZAEB 1XKAL 4MMZB 1TOZA 2W2ME 5IKTA 4LORA 2P3FL 2IUNA 3QCWA 1FAXL 4ZXXL 1WHEA 1P6AA 3N8XA 2Y7ZB 2ADXA 4CUDA 3HS7A 5CKQA 5F1AA 2PUQL 1Q4GA 1DIYA 1QIUA 4ZXYL 4X8SL 4BDXA 4X8VL 4PH9A 3ENSA 1HREA 2BQ6A 1XDTR 3HO4A 5CISA 4M11A 1CEJA 2O39A 1IQIL 1RFNB 4RS0A 1ATEA 1EPJA 2W86A 2WPLE 1EMNA 1ATAA 2KV4A 3KQEL 4G1MB 1F7EA 1CCFA 1V1HA 2FLBL 3HS6A 1DQBA 1CVUA 1IOEL 3GCXE 4NA9L 5E8DA 3M37L 4BTUA 1NFYB 5JVYA 1G1QA 2IUMA 3ZYIB 1JL9A 1NQLB 3Q7DA 1KLOA 4MMYB 2VJ3A 2VWMK 2FZZL 2M74A 3P5BL 1NFXB 4XC5A 1NPEB 3TH3L 3S6XA 2VTWA 1EQHA 1V3XB 1LMJA 1FFMA 1ATDA 3O8EA 2CJIB 2MHPA 3SOVA 1TLEA 2RHPA 2WG3C 1WU1B 2D1JB 1EZQB 1F7MA 2B7DL 2J4IB 2P3FN 1XKBA 2BQ7A 2W2NE 2WGUA 3TBDA 2WPHE 1EGFA 4LIYA 2RNLA 4XBMA 5JB8E 1KIGL 1KNBA 1G2MB 2WYJB 2VRSA 1UXAA 1EPGA 2RA0L 4CW8A 4XQBA 4BDWA 1CQEA 1EBVA 2XC5L 1FE2A 2DDUA 2WFTA 1IQGL 1WHFA 4D0EA 1EMOA 2VWLL 3EXWA 3HO3A 1NOBA 3TGFA 5L2ZL 4ISHL 4M10A 2Y5HL 4BXSA 1KACA 2K2SB 3LAQA 4JYVL 1NFUB 5IKRA 1P9JA 4BTIA 3TZIA 3OLTA 1FJSL 1NFWB 3F1SB 2TGFA 5JVZA 1G1TA 2YGOA 2WPJE 1CCVA 1O5DL 3U73A 2EI8B 4ODBA 1C5MF 3M36L 3SOBB 2WBWA 4K6VA 4K6UA 2Q1JB 1LPKA 1YUKB 4OTJA 3GISX 3SOQA 1G1SA 2J94B 3KK6A 4D63A 6COXA 1DDXA 1Z6CA 2W2OE 2VH0B 2W3IB 2XC0L 2BO2A 2JJLA 2VWNL 4RRZA 3HS5A 3H5CB 4RRXA 5L30L 2PHBB 3ZYJB 2XBVL 5JBCE 3KRKA 1GK5A 4TGFA 4Z0KB 2W3KB 2BOHA 2UWOB 3ZYGA 4YT7L 2VVCK 2BT7A 2FD6A 2P93L 2QLKA 1PRHA 5IKVA 2OJ6A 2WG4B 3MDLA 1QHVA 2FLRL 1IQML 1PFXL 3BT2A 1IGXA 1W8BL 2KNIA 2BOUA 2F9BL 1ADXA 1IQKL 1EPIA 1UXBA 3ASIA 2WPME 4ISIL 3N8VA 2J2UB 1A3PA 3LTGD 3V64C 3PGHA 1P69A 2P94L 2EI7B 2XBXL 1NT0A 2UWLB 1FF7A 1BF9A 2W2QE 5JB9E 4XQAA 2Y81B 4OTYA 3IJEB 2I9BA 1LPGA 2BZVA 2OYEP 5MHSA 1YGCL 1ZAQA 3KCGL 2OYUP 3TK6B 1UZJA 4RRYA 1L5GB 4JYUL 3BT1A 2VWOL 1UZPA 4BXWA 4XL8A 3OLUA 4WYJA 3Q3KB 1HT5A 1MQ5L 3K9XA 4C16A 3MQEA 1LPZA 1UXEA 1N7DA 1B9WA 2P16L 2WZPP 4ZHAB 1JBUL 4YT6L 1OB1C 1FAKL 2K2TA 4K6TA 4CUEA 4Z0LA 4XL1A 3FBYA 4JZFL 1U8CB 2AYLA 3QH0A 1K36A 2WPIE 3L88A 1HCGB 4A94C 1MQ6L 5FDQA 2WSTA 2Y5FL 3SW2A 4NGAL 2FLGA 1N1IA 2I9AA 3F0YA 4Z6AL 1IQLL 3ZPFA 1UZKA 3V65B 4Y6DB 3C9AC 5JBBE 3CA7A 2BOXA 5COXA 2OJ5A 2P95L 2XC4L 1YO8A 5IKQA 3N8WB 4GU4A 2W2PE 2UWPB 2BSFA 5JBAE 3FFGL 5I46L 4D0FA 1APQA 2WGTA 3F6UL 2BMGA 2J38B 2BOKL 1XFEA 3EXVA 2HORA 4RUTA 3RR3A 3U7UG 3KQCL 4JZEL 3N8YB 1G1RA 2H9EL 1IQFL 2J2JA 1IJQA 2W26B 1HZ8A 1CVWL 3CFWA 3CNCA 1M1XB 1MOXC 1Z6EL 2Y7XB 1KLJL 1X7AL 4O1ZA 5JW1A 1H7ZA 2BZUA 2MGRA 2W9LC 1HAEA 4GU3A 1P0SL 1SZBA 2G00L 2YGPA 3NJPC 4ZDGA 1URKA 4O02B 1IOXA 1PXXA 1NZIA 1IQHL 4Y71B 1APOA 4ATZA 1DX5I 2WYGB 1EQGA 5KIRA 1J9CL 1IP0A 2KL7A 4JZDL 4COXA 2JKHL 1COUA 5CKMA 2WPKE 3LC3B 1YUFA 1IQEL 2EI6B 2Y80B 3ZPEA 3EOYA 1KLIL 2WFXB 2KB9A 3QMOA 1IQJL
chains in the Genus database with same CATH topology
2OJ5A 2JJLA 2BT8A 4GU3A 2OJ6A 2BT7A 5MHSA 3EOYA 4XC5A 1KKEA 1V1IA 1V1HA 2VRSA 1QIUA 4GU4A 4ODBA 3S6XA 2BSFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OJ5 A;  2JJL A;  2BT8 A;  4GU3 A;  2OJ6 A;  2BT7 A;  5MHS A;  3EOY A;  4XC5 A;  1KKE A;  1V1I A;  1V1H A;  2VRS A;  1QIU A;  4GU4 A;  4ODB A;  3S6X A;  2BSF A; 
#chains in the Genus database with same CATH topology
 1IGZ A;  1QFK L;  1HAF A;  1PTH A;  5F19 A;  3LTF B;  4BTT A;  3CS7 L;  3LC5 B;  1YUG A;  4D62 A;  3FCS B;  4E1G A;  5KN5 C;  2P28 B;  2H9E C;  3LIW B;  4LMF A;  1HX2 A;  5L2Y L;  5EGM B;  1FSB A;  1F0R B;  3EGF A;  1LMM A;  1UZQ A;  1ATB A;  4X8T L;  2MGP A;  5CKN A;  2P3U A;  1CX2 A;  2GD4 A;  4FM5 A;  4NG9 L;  4ZH8 B;  2NPR A;  2HOX A;  1IQN L;  1V1I A;  3LN0 A;  4D90 A;  1HRF A;  2BT8 A;  1U67 A;  2J1K C;  4Y7A B;  3KQB L;  3ELA L;  1TPG A;  3DEM A;  4Y79 B;  1DVA L;  3N0I A;  2VVV L;  4A7I A;  4AQT A;  3BQ4 A;  2P26 A;  2XBY L;  3L89 A;  1G2L B;  3HO5 A;  2J34 B;  1KKE A;  1F0S B;  2Y38 A;  1L3Y A;  3LN1 A;  2PR3 B;  2J12 A;  1EAI C;  1HT8 A;  2YGQ A;  1K37 A;  4Y76 B;  3NTB A;  3R05 A;  1IVO C;  3NT1 A;  4RRW A;  2WBV A;  2VVU L;  2J95 B;  4X8U L;  1PGE A;  2BZ6 L;  3QND A;  3HPT A;  4CUF A;  3KQD L;  4MMX B;  3BPS E;  1EPH A;  3KL6 B;  3N8W A;  4K6W A;  3NTG A;  2Y82 B;  2P3T A;  3N8Z A;  1AUT L;  2BQW A;  4XLW A;  3TK5 B;  3POY A;  4CSY A;  4Y7B B;  1JV2 B;  4YZU B;  5K0H B;  2VH6 B;  1KSN B;  1LK9 A;  3CEN L;  3GCW E;  1W7X L;  1I0U A;  1LQD A;  2XBW L;  1HJ7 A;  2Y5G L;  3IIT B;  3N8Y A;  4ZAE B;  1XKA L;  4MMZ B;  1TOZ A;  2W2M E;  5IKT A;  4LOR A;  2P3F L;  2IUN A;  3QCW A;  1FAX L;  4ZXX L;  1WHE A;  1P6A A;  3N8X A;  2Y7Z B;  2ADX A;  4CUD A;  3HS7 A;  5CKQ A;  5F1A A;  2PUQ L;  1Q4G A;  1DIY A;  1QIU A;  4ZXY L;  4X8S L;  4BDX A;  4X8V L;  4PH9 A;  3ENS A;  1HRE A;  2BQ6 A;  1XDT R;  3HO4 A;  5CIS A;  4M11 A;  1CEJ A;  2O39 A;  1IQI L;  1RFN B;  4RS0 A;  1ATE A;  1EPJ A;  2W86 A;  2WPL E;  1EMN A;  1ATA A;  2KV4 A;  3KQE L;  4G1M B;  1F7E A;  1CCF A;  1V1H A;  2FLB L;  3HS6 A;  1DQB A;  1CVU A;  1IOE L;  3GCX E;  4NA9 L;  5E8D A;  3M37 L;  4BTU A;  1NFY B;  5JVY A;  1G1Q A;  2IUM A;  3ZYI B;  1JL9 A;  1NQL B;  3Q7D A;  1KLO A;  4MMY B;  2VJ3 A;  2VWM K;  2FZZ L;  2M74 A;  3P5B L;  1NFX B;  4XC5 A;  1NPE B;  3TH3 L;  3S6X A;  2VTW A;  1EQH A;  1V3X B;  1LMJ A;  1FFM A;  1ATD A;  3O8E A;  2CJI B;  2MHP A;  3SOV A;  1TLE A;  2RHP A;  2WG3 C;  1WU1 B;  2D1J B;  1EZQ B;  1F7M A;  2B7D L;  2J4I B;  2P3F N;  1XKB A;  2BQ7 A;  2W2N E;  2WGU A;  3TBD A;  2WPH E;  1EGF A;  4LIY A;  2RNL A;  4XBM A;  5JB8 E;  1KIG L;  1KNB A;  1G2M B;  2WYJ B;  2VRS A;  1UXA A;  1EPG A;  2RA0 L;  4CW8 A;  4XQB A;  4BDW A;  1CQE A;  1EBV A;  2XC5 L;  1FE2 A;  2DDU A;  2WFT A;  1IQG L;  1WHF A;  4D0E A;  1EMO A;  2VWL L;  3EXW A;  3HO3 A;  1NOB A;  3TGF A;  5L2Z L;  4ISH L;  4M10 A;  2Y5H L;  4BXS A;  1KAC A;  2K2S B;  3LAQ A;  4JYV L;  1NFU B;  5IKR A;  1P9J A;  4BTI A;  3TZI A;  3OLT A;  1FJS L;  1NFW B;  3F1S B;  2TGF A;  5JVZ A;  1G1T A;  2YGO A;  2WPJ E;  1CCV A;  1O5D L;  3U73 A;  2EI8 B;  4ODB A;  1C5M F;  3M36 L;  3SOB B;  2WBW A;  4K6V A;  4K6U A;  2Q1J B;  1LPK A;  1YUK B;  4OTJ A;  3GIS X;  3SOQ A;  1G1S A;  2J94 B;  3KK6 A;  4D63 A;  6COX A;  1DDX A;  1Z6C A;  2W2O E;  2VH0 B;  2W3I B;  2XC0 L;  2BO2 A;  2JJL A;  2VWN L;  4RRZ A;  3HS5 A;  3H5C B;  4RRX A;  5L30 L;  2PHB B;  3ZYJ B;  2XBV L;  5JBC E;  3KRK A;  1GK5 A;  4TGF A;  4Z0K B;  2W3K B;  2BOH A;  2UWO B;  3ZYG A;  4YT7 L;  2VVC K;  2BT7 A;  2FD6 A;  2P93 L;  2QLK A;  1PRH A;  5IKV A;  2OJ6 A;  2WG4 B;  3MDL A;  1QHV A;  2FLR L;  1IQM L;  1PFX L;  3BT2 A;  1IGX A;  1W8B L;  2KNI A;  2BOU A;  2F9B L;  1ADX A;  1IQK L;  1EPI A;  1UXB A;  3ASI A;  2WPM E;  4ISI L;  3N8V A;  2J2U B;  1A3P A;  3LTG D;  3V64 C;  3PGH A;  1P69 A;  2P94 L;  2EI7 B;  2XBX L;  1NT0 A;  2UWL B;  1FF7 A;  1BF9 A;  2W2Q E;  5JB9 E;  4XQA A;  2Y81 B;  4OTY A;  3IJE B;  2I9B A;  1LPG A;  2BZV A;  2OYE P;  5MHS A;  1YGC L;  1ZAQ A;  3KCG L;  2OYU P;  3TK6 B;  1UZJ A;  4RRY A;  1L5G B;  4JYU L;  3BT1 A;  2VWO L;  1UZP A;  4BXW A;  4XL8 A;  3OLU A;  4WYJ A;  3Q3K B;  1HT5 A;  1MQ5 L;  3K9X A;  4C16 A;  3MQE A;  1LPZ A;  1UXE A;  1N7D A;  1B9W A;  2P16 L;  2WZP P;  4ZHA B;  1JBU L;  4YT6 L;  1OB1 C;  1FAK L;  2K2T A;  4K6T A;  4CUE A;  4Z0L A;  4XL1 A;  3FBY A;  4JZF L;  1U8C B;  2AYL A;  3QH0 A;  1K36 A;  2WPI E;  3L88 A;  1HCG B;  4A94 C;  1MQ6 L;  5FDQ A;  2WST A;  2Y5F L;  3SW2 A;  4NGA L;  2FLG A;  1N1I A;  2I9A A;  3F0Y A;  4Z6A L;  1IQL L;  3ZPF A;  1UZK A;  3V65 B;  4Y6D B;  3C9A C;  5JBB E;  3CA7 A;  2BOX A;  5COX A;  2OJ5 A;  2P95 L;  2XC4 L;  1YO8 A;  5IKQ A;  3N8W B;  4GU4 A;  2W2P E;  2UWP B;  2BSF A;  5JBA E;  3FFG L;  5I46 L;  4D0F A;  1APQ A;  2WGT A;  3F6U L;  2BMG A;  2J38 B;  2BOK L;  1XFE A;  3EXV A;  2HOR A;  4RUT A;  3RR3 A;  3U7U G;  3KQC L;  4JZE L;  3N8Y B;  1G1R A;  2H9E L;  1IQF L;  2J2J A;  1IJQ A;  2W26 B;  1HZ8 A;  1CVW L;  3CFW A;  3CNC A;  1M1X B;  1MOX C;  1Z6E L;  2Y7X B;  1KLJ L;  1X7A L;  4O1Z A;  5JW1 A;  1H7Z A;  2BZU A;  2MGR A;  2W9L C;  1HAE A;  4GU3 A;  1P0S L;  1SZB A;  2G00 L;  2YGP A;  3NJP C;  4ZDG A;  1URK A;  4O02 B;  1IOX A;  1PXX A;  1NZI A;  1IQH L;  4Y71 B;  1APO A;  4ATZ A;  1DX5 I;  2WYG B;  1EQG A;  5KIR A;  1J9C L;  1IP0 A;  2KL7 A;  4JZD L;  4COX A;  2JKH L;  1COU A;  5CKM A;  2WPK E;  3LC3 B;  1YUF A;  1IQE L;  2EI6 B;  2Y80 B;  3ZPE A;  3EOY A;  1KLI L;  2WFX B;  2KB9 A;  3QMO A;  1IQJ L; 
#chains in the Genus database with same CATH homology
 2OJ5 A;  2JJL A;  2BT8 A;  4GU3 A;  2OJ6 A;  2BT7 A;  5MHS A;  3EOY A;  4XC5 A;  1KKE A;  1V1I A;  1V1H A;  2VRS A;  1QIU A;  4GU4 A;  4ODB A;  3S6X A;  2BSF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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