4H3XA

Crystal structure of an mmp broad spectrum hydroxamate based inhibitor cc27 in complex with the mmp-9 catalytic domain
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
164
structure length
164
Chain Sequence
GFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallization of bi-functional ligand protein complexes.
pubmed doi rcsb
molecule keywords Matrix metalloproteinase-9
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 47
structure length 164
sequence length 164
chains with identical sequence B
ec nomenclature ec 3.4.24.35: Gelatinase B.
pdb deposition date 2012-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4h3xA00
1YQYA 2WO8A 4XM6A 1MNCA 2XS3A 2Y6CA 2DW1A 3TVCA 4HX3A 5D3CA 1KUFA 2Y6DA 4AYKA 1OMJA 1BKCI 3LK8A 3EDHA 2AIGP 1DMTA 4DV8A 1O0QA 1FBLA 1UEAA 3L0VA 1D8FA 3DL1A 5I0LA 1C7KA 2OXWA 1ZTQA 4PKTA 1JK3A 1R55A 3LJZA 3V96B 4FXQA 1O0TA 4JPAA 3Q2GA 1XFVA 3E8RA 4PKQA 3G42A 1BQQM 4JP4A 5BOYA 5I12A 1EB6A 1UMTA 3F18A 1JAPA 1JAOA 4G0DA 3F15A 4ILWD 1R1IA 1YCMA 1Q3AA 4AUOA 1JIZA 5I3MA 4GR8A 3AYKA 3F17A 2ERPA 4GF1A 1YP1A 1HTDA 3L0TA 1BZSA 4GR0A 1CGLA 1UTZA 2QPJA 4H3XA 2OZRA 2JT6A 3ZXHA 4AIGA 830CA 1QJIA 2WOAA 2OVXA 3LIKA 1GO8P 3RTTA 2E2DA 4DF9A 3DNGA 1IABA 2W12A 4GR3A 1MMPA 1J7NA 1HFSA 4L19A 2JIHA 3B2ZA 2OY2A 4H82A 1IACA 1K7IA 1OO9A 2E3XA 3EDZA 3UVCA 1JAQA 2AYKA 4XM7A 5CXAA 2K2GA 1XFWA 2USNA 3USNA 4DPEA 2OW1A 1EUBA 3O64A 4GUYA 1G4KA 1BIWA 1GE6A 1D8MA 3KEJA 1EAKA 1I73A 3F16A 1MMQA 3F19A 4GQLA 1SLMA 3LIRA 5BOTA 3KEKA 2W15A 4JQGA 3ELMA 2J83A 1Y93A 2L0RA 2RJPA 1HV5A 1UMSA 4G9LA 3GBOA 2KRJA 3LEAA 3TS4A 3HDAP 2RJQA 3EHXA 3ZUKA 1BKCE 2TCLA 1ZXVA 4ON1A 3VTGA 4IN9A 1GO7P 4WKIA 2JT5A 3ZVSA 1ZXCA 5I43A 4IJOA 1ROSA 2OW9A 4CTHA 1BM6A 1OM8A 1AKLA 2CKIA 1CAQA 3OHOA 4FVLA 3LUNA 3BA0A 4DD8A 1ATLA 3P24A 1C3IA 1ASTA 1PWPA 4Q1LA 2MZHA 1PWVA 3CKIA 3SHIA 1G12A 1BUVM 1XUCA 2WO9A 5I4OA 3EDGA 3TSKA 1SRPA 4H76A 1XUDA 3KMEA 966CA 456CA 5CZMA 4J4MA 3WV3A 1QJJA 4HMAA 5L79A 3N2VA 1PWWA 1QIAA 1PWUA 4I35A 3U1RA 2MZEA 1IADA 4QKZA 2EROA 3EWJA 2O36A 4I03A 1FLSA 5BPAA 1KUGA 1RMZA 3HB2P 2PJTA 1GKCA 3Q2HA 2J0TA 2OXUA 1QIBA 4WZVA 2W0DA 1OS9A 1IAGA 1ZS0A 1BSWA 3I7IA 5D2BA 1I76A 3N2UA 4WK7A 1K7GA 2N8RA 1KBCA 1R54A 5B5OA 4PKRA 3HDBA 4GWMA 3P1VA 2YIGA 1KAPP 4PKSA 3WV1A 1SU3A 3VI1A 4AXQA 1ND1A 1G49A 4A3WA 2X3BA 1L6JA 1PWQA 3HBVP 1AYKA 1XURA 3K7LA 4H49A 1YOUA 2JNPA 1XFZA 1Y0VA 2MZIA 4FU4A 1OS2A 2MLSA 1GXDA 1QICA 3WV2A 1IAEA 4A7BA 3DWBA 1HFCA 2OW0A 5CUHA 3LGPA 4XCTA 1KUHA 3G5CA 3K7NA 2X3CA 2HU6A 3HY7A 1ZVXA 1A86A 3LKAA 3DSLA 2OY4A 3KWVC 3TT4A 1B8YA 1GKDA 2DW2A 4R3VA 2D1NA 4GWNA 1AF0A 1SATA 4XM8A 2OVZA 3DPEA 2Z2DA 1I1IP 3KRYA 1GE7A 2MLRA 2DDFA 2X7MA 3EDIA 2POJA 1MMRA 1KUIA 3MA2A 1JH1A 1K7QA 5I2ZA 1USNA 2JSDA 3AYUA 2A8HA 2OW2A 1CIZA 1MMBA 1G9KA 5D1SA 3AIGA 2XS4A 1CXVA 3B8ZA 3NX7A 4XBHA 1D7XA 3LMCA 5D7WA 1C8TA 1OM7A 3LQBA 5D1TA 1IAAA 3LE9A 1BUDA 1JJ9A 1H71P 1SLNA 3LUMA 1JIWP 1WNIA 1HY7A 2OI0A 4FXYP 1HOVA 1KUKA 2FV5A 1R1JA 5L7FA 1XFXA 3LILA 1SMPA 1QUAA 3EHYA 1BKCA 2K9CA 2X3AA 2W14A 4H2EA 4PKUA 1GE5A 1RM8A 4JA1A 4PKWA 3HY9A 3HYGA 4WF6A 5H8XA 1JKYA 4H84A 2DDYA 2ERQA 1XFUA 4H1QA 4H30A 2DW0A 4PKVA 2FV9A 4IUWA 4EFSA 5B5PA 3KECA 5LABA 5JMYA 2I47A 5D1UA 1JANA 1UTTA 2SRTA 1A85A 2O3EA 3I7GA 1D5JA 1DTHA 1CQRA 1XFYA 1R1HA 1CGFA 1CGEA 3HBUP 3OHLA 4L63A 3KHIA 1Y8JA 4WKEA 2V4BA 3F1AA 1FM1A 3RTSA 2CLTA 3O2XA 1CK7A 1B3DA 4L6TA 2W13A 3LQ0A 3LJGA 1G05A 1OM6A 1S4BP 3B92A 1BQOA 1ZP5A 2OXZA 4JIJA 2YB9A 3DPFA 3LJTA 3KMCA 2D1OA 4ZR5A 1Z3JA
chains in the Genus database with same CATH superfamily
1YQYA 2WO8A 4XM6A 1MNCA 2XS3A 2Y6CA 2DW1A 3TVCA 4HX3A 5D3CA 1KUFA 2Y6DA 4AYKA 1OMJA 1BKCI 3LK8A 3EDHA 2AIGP 1DMTA 4DV8A 1O0QA 1FBLA 1UEAA 3L0VA 1D8FA 3DL1A 5I0LA 1C7KA 2OXWA 1ZTQA 4PKTA 1JK3A 1R55A 3LJZA 3V96B 4FXQA 1O0TA 4JPAA 3Q2GA 1XFVA 3E8RA 4PKQA 3G42A 1BQQM 4JP4A 5BOYA 5I12A 1EB6A 1UMTA 3F18A 1JAPA 1JAOA 4G0DA 3F15A 4ILWD 1R1IA 1YCMA 1Q3AA 4AUOA 1JIZA 5I3MA 4GR8A 3AYKA 3F17A 2ERPA 4GF1A 1YP1A 1HTDA 3L0TA 1BZSA 4GR0A 1CGLA 1UTZA 2QPJA 2YUFA 4H3XA 2OZRA 2JT6A 3ZXHA 4AIGA 830CA 1QJIA 2WOAA 2OVXA 3LIKA 1GO8P 3RTTA 2E2DA 4DF9A 3DNGA 1IABA 2W12A 4GR3A 1MMPA 1J7NA 1HFSA 4L19A 3DTEA 2JIHA 3B2ZA 2OY2A 4H82A 1IACA 1K7IA 1OO9A 2E3XA 3EDZA 3UVCA 1JAQA 2AYKA 4XM7A 5CXAA 2K2GA 1XFWA 2USNA 3USNA 4DPEA 2OW1A 1EUBA 3O64A 4GUYA 1G4KA 1BIWA 1GE6A 1D8MA 3KEJA 1EAKA 1I73A 3F16A 1MMQA 3F19A 4GQLA 1SLMA 3LIRA 5BOTA 3KEKA 2W15A 4JQGA 3ELMA 2J83A 1Y93A 2L0RA 2RJPA 1HV5A 1UMSA 4G9LA 3GBOA 2KRJA 3LEAA 3TS4A 3HDAP 2RJQA 3EHXA 3ZUKA 1BKCE 2TCLA 1ZXVA 4ON1A 3VTGA 4IN9A 1GO7P 4WKIA 2JT5A 3ZVSA 1ZXCA 5I43A 4IJOA 1ROSA 2OW9A 4CTHA 1BM6A 1OM8A 3DTKA 1AKLA 2CKIA 1CAQA 3OHOA 4FVLA 3LUNA 3BA0A 4DD8A 1ATLA 3P24A 1C3IA 1ASTA 1PWPA 4Q1LA 2MZHA 1PWVA 3CKIA 3SHIA 1G12A 1BUVM 1XUCA 2WO9A 5I4OA 3EDGA 3TSKA 1SRPA 4H76A 1XUDA 3KMEA 4L7AA 966CA 456CA 5CZMA 4J4MA 3WV3A 1QJJA 4HMAA 5L79A 3DTIA 3N2VA 1PWWA 1QIAA 1PWUA 4I35A 3U1RA 2MZEA 1IADA 4QKZA 2EROA 3EWJA 2O36A 4I03A 1FLSA 5BPAA 1KUGA 1RMZA 3HB2P 2PJTA 1GKCA 3Q2HA 2J0TA 2OXUA 1QIBA 4WZVA 2W0DA 1OS9A 1IAGA 1ZS0A 1BSWA 3I7IA 5D2BA 1I76A 3N2UA 4WK7A 1K7GA 2N8RA 1KBCA 1R54A 5B5OA 4PKRA 3HDBA 4GWMA 3P1VA 2YIGA 1KAPP 4PKSA 3WV1A 1SU3A 3VI1A 4AXQA 1ND1A 1G49A 4A3WA 2X3BA 1L6JA 1PWQA 3HBVP 1AYKA 1XURA 3K7LA 4H49A 1YOUA 2JNPA 1XFZA 1Y0VA 2MZIA 4FU4A 1OS2A 2MLSA 1GXDA 1QICA 3WV2A 1IAEA 4A7BA 3DWBA 1HFCA 2OW0A 5CUHA 3LGPA 4XCTA 1KUHA 3G5CA 3K7NA 2X3CA 2HU6A 3HY7A 1ZVXA 1A86A 3LKAA 3DSLA 1XM5A 2OY4A 3KWVC 3TT4A 1B8YA 1GKDA 2DW2A 4R3VA 2D1NA 4GWNA 1AF0A 1SATA 4XM8A 2OVZA 3DPEA 2Z2DA 1I1IP 3KRYA 1GE7A 2MLRA 2DDFA 2X7MA 3EDIA 2POJA 1MMRA 1KUIA 3MA2A 1JH1A 1K7QA 5I2ZA 1USNA 2JSDA 3AYUA 2A8HA 2OW2A 1CIZA 1MMBA 1G9KA 5D1SA 3AIGA 2XS4A 1CXVA 3B8ZA 3NX7A 4XBHA 1D7XA 3LMCA 5D7WA 1C8TA 1OM7A 3LQBA 5D1TA 1IAAA 3LE9A 1BUDA 1JJ9A 1H71P 1SLNA 3LUMA 1JIWP 1WNIA 1HY7A 2OI0A 4FXYP 1HOVA 1KUKA 2FV5A 1R1JA 5L7FA 1XFXA 3LILA 1SMPA 1QUAA 3EHYA 1BKCA 2K9CA 2X3AA 2W14A 4H2EA 4PKUA 1GE5A 1RM8A 4JA1A 4PKWA 3HY9A 3HYGA 4WF6A 5H8XA 1JKYA 4H84A 2DDYA 2ERQA 1XFUA 4H1QA 4H30A 2DW0A 4PKVA 2FV9A 4IUWA 4EFSA 5B5PA 3KECA 5LABA 5JMYA 2I47A 5D1UA 1JANA 1UTTA 2SRTA 1A85A 2O3EA 3I7GA 1TVIA 1D5JA 1DTHA 1CQRA 1XFYA 1XAXA 1R1HA 1CGFA 1CGEA 3HBUP 3OHLA 4L63A 1OZ9A 3KHIA 1Y8JA 4WKEA 2V4BA 3F1AA 1FM1A 3RTSA 2CLTA 3O2XA 1CK7A 1B3DA 4L6TA 2W13A 3LQ0A 3LJGA 1G05A 1OM6A 1S4BP 3B92A 1BQOA 1ZP5A 2OXZA 4JIJA 2YB9A 3DPFA 3LJTA 3KMCA 2D1OA 4ZR5A 1Z3JA
chains in the Genus database with same CATH topology
1YQYA 2WO8A 4XM6A 1MNCA 2XS3A 2Y6CA 2DW1A 3TVCA 4HX3A 5D3CA 1KUFA 2Y6DA 4AYKA 1OMJA 1BKCI 3LK8A 3EDHA 2AIGP 1DMTA 4DV8A 1O0QA 1FBLA 1UEAA 3L0VA 1D8FA 3DL1A 5I0LA 1C7KA 2OXWA 1ZTQA 4PKTA 1JK3A 1R55A 3LJZA 3V96B 4FXQA 1O0TA 4JPAA 3Q2GA 1XFVA 3E8RA 4PKQA 3G42A 1BQQM 4JP4A 5BOYA 5I12A 1EB6A 1UMTA 3F18A 1JAPA 1JAOA 4G0DA 3F15A 4ILWD 1R1IA 1YCMA 1Q3AA 4AUOA 1JIZA 5I3MA 4GR8A 3AYKA 3F17A 2ERPA 4GF1A 1YP1A 1HTDA 3L0TA 1BZSA 4GR0A 1CGLA 1UTZA 2QPJA 2YUFA 4H3XA 2OZRA 2JT6A 3ZXHA 4AIGA 830CA 1QJIA 2WOAA 2OVXA 3LIKA 1GO8P 3RTTA 2E2DA 4DF9A 3DNGA 1IABA 2W12A 4GR3A 1MMPA 1J7NA 1HFSA 4L19A 3DTEA 2JIHA 3B2ZA 2OY2A 4H82A 1IACA 1K7IA 1OO9A 2E3XA 3EDZA 3UVCA 1JAQA 2AYKA 4XM7A 5CXAA 2K2GA 1XFWA 2USNA 3USNA 4DPEA 2OW1A 1EUBA 3O64A 4GUYA 1G4KA 1BIWA 1GE6A 1D8MA 3KEJA 1EAKA 1I73A 3F16A 1MMQA 3F19A 4GQLA 1SLMA 3LIRA 5BOTA 3KEKA 2W15A 4JQGA 3ELMA 2J83A 1Y93A 2L0RA 2RJPA 1HV5A 1UMSA 4G9LA 3GBOA 2KRJA 3LEAA 3TS4A 3HDAP 2RJQA 3EHXA 3ZUKA 1BKCE 2TCLA 1ZXVA 4ON1A 3VTGA 4IN9A 1GO7P 4WKIA 2JT5A 3ZVSA 1ZXCA 5I43A 4IJOA 1ROSA 2OW9A 4CTHA 1BM6A 1OM8A 3DTKA 1AKLA 2CKIA 1CAQA 3OHOA 4FVLA 3LUNA 3BA0A 4DD8A 1ATLA 3P24A 1C3IA 1ASTA 1PWPA 4Q1LA 2MZHA 1PWVA 3CKIA 3SHIA 1G12A 1BUVM 1XUCA 2WO9A 5I4OA 3EDGA 3TSKA 1SRPA 4H76A 1XUDA 3KMEA 4L7AA 966CA 456CA 5CZMA 4J4MA 3WV3A 1QJJA 4HMAA 5L79A 3DTIA 3N2VA 1PWWA 1QIAA 1PWUA 4I35A 3U1RA 2MZEA 1IADA 4QKZA 2EROA 3EWJA 2O36A 4I03A 1FLSA 5BPAA 1KUGA 1RMZA 3HB2P 2PJTA 1GKCA 3Q2HA 2J0TA 2OXUA 1QIBA 4WZVA 2W0DA 1OS9A 1IAGA 1ZS0A 1BSWA 3I7IA 5D2BA 1I76A 3N2UA 4WK7A 1K7GA 2N8RA 1KBCA 1R54A 5B5OA 4PKRA 3HDBA 4GWMA 3P1VA 2YIGA 1KAPP 4PKSA 3WV1A 1SU3A 3VI1A 4AXQA 1ND1A 1G49A 4A3WA 2X3BA 1L6JA 1PWQA 3HBVP 1AYKA 1XURA 3K7LA 4H49A 1YOUA 2JNPA 1XFZA 1Y0VA 2MZIA 4FU4A 1OS2A 2MLSA 1GXDA 1QICA 3WV2A 1IAEA 4A7BA 3DWBA 1HFCA 2OW0A 5CUHA 3LGPA 4XCTA 1KUHA 3G5CA 3K7NA 2X3CA 2HU6A 3HY7A 1ZVXA 1A86A 3LKAA 3DSLA 2OY4A 3KWVC 3TT4A 1B8YA 1GKDA 2DW2A 4R3VA 2D1NA 4GWNA 1AF0A 1SATA 4XM8A 2OVZA 3DPEA 2Z2DA 1I1IP 3KRYA 1GE7A 2MLRA 2DDFA 2X7MA 3EDIA 2POJA 1MMRA 1KUIA 3MA2A 1JH1A 1K7QA 5I2ZA 1USNA 2JSDA 3AYUA 2A8HA 2OW2A 1CIZA 1MMBA 1G9KA 5D1SA 3AIGA 2XS4A 1CXVA 3B8ZA 3NX7A 4XBHA 1D7XA 3LMCA 5D7WA 1C8TA 1OM7A 3LQBA 5D1TA 1IAAA 3LE9A 1BUDA 1JJ9A 1H71P 1SLNA 3LUMA 1JIWP 1WNIA 1HY7A 2OI0A 4FXYP 1HOVA 1KUKA 2FV5A 1R1JA 5L7FA 1XFXA 3LILA 1SMPA 1QUAA 3EHYA 1BKCA 2K9CA 2X3AA 2W14A 4H2EA 4PKUA 1GE5A 1RM8A 4JA1A 4PKWA 3HY9A 3HYGA 4WF6A 5H8XA 1JKYA 4H84A 2DDYA 2ERQA 1XFUA 4H1QA 4H30A 2DW0A 4PKVA 2FV9A 4IUWA 4EFSA 5B5PA 3KECA 5LABA 5JMYA 2I47A 5D1UA 1JANA 1UTTA 2SRTA 1A85A 2O3EA 3I7GA 1D5JA 1DTHA 1CQRA 1XFYA 1R1HA 1CGFA 1CGEA 3HBUP 3OHLA 4L63A 3KHIA 1Y8JA 4WKEA 2V4BA 3F1AA 1FM1A 3RTSA 2CLTA 3O2XA 1CK7A 1B3DA 4L6TA 2W13A 3LQ0A 3LJGA 1G05A 1OM6A 1S4BP 3B92A 1BQOA 1ZP5A 2OXZA 4JIJA 2YB9A 3DPFA 3LJTA 3KMCA 2D1OA 4ZR5A 1Z3JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YQY A;  2WO8 A;  4XM6 A;  1MNC A;  2XS3 A;  2Y6C A;  2DW1 A;  3TVC A;  4HX3 A;  5D3C A;  1KUF A;  2Y6D A;  4AYK A;  1OMJ A;  1BKC I;  3LK8 A;  3EDH A;  2AIG P;  1DMT A;  4DV8 A;  1O0Q A;  1FBL A;  1UEA A;  3L0V A;  1D8F A;  3DL1 A;  5I0L A;  1C7K A;  2OXW A;  1ZTQ A;  4PKT A;  1JK3 A;  1R55 A;  3LJZ A;  3V96 B;  4FXQ A;  1O0T A;  4JPA A;  3Q2G A;  1XFV A;  3E8R A;  4PKQ A;  3G42 A;  1BQQ M;  4JP4 A;  5BOY A;  5I12 A;  1EB6 A;  1UMT A;  3F18 A;  1JAP A;  1JAO A;  4G0D A;  3F15 A;  4ILW D;  1R1I A;  1YCM A;  1Q3A A;  4AUO A;  1JIZ A;  5I3M A;  4GR8 A;  3AYK A;  3F17 A;  2ERP A;  4GF1 A;  1YP1 A;  1HTD A;  3L0T A;  1BZS A;  4GR0 A;  1CGL A;  1UTZ A;  2QPJ A;  4H3X A;  2OZR A;  2JT6 A;  3ZXH A;  4AIG A;  830C A;  1QJI A;  2WOA A;  2OVX A;  3LIK A;  1GO8 P;  3RTT A;  2E2D A;  4DF9 A;  3DNG A;  1IAB A;  2W12 A;  4GR3 A;  1MMP A;  1J7N A;  1HFS A;  4L19 A;  2JIH A;  3B2Z A;  2OY2 A;  4H82 A;  1IAC A;  1K7I A;  1OO9 A;  2E3X A;  3EDZ A;  3UVC A;  1JAQ A;  2AYK A;  4XM7 A;  5CXA A;  2K2G A;  1XFW A;  2USN A;  3USN A;  4DPE A;  2OW1 A;  1EUB A;  3O64 A;  4GUY A;  1G4K A;  1BIW A;  1GE6 A;  1D8M A;  3KEJ A;  1EAK A;  1I73 A;  3F16 A;  1MMQ A;  3F19 A;  4GQL A;  1SLM A;  3LIR A;  5BOT A;  3KEK A;  2W15 A;  4JQG A;  3ELM A;  2J83 A;  1Y93 A;  2L0R A;  2RJP A;  1HV5 A;  1UMS A;  4G9L A;  3GBO A;  2KRJ A;  3LEA A;  3TS4 A;  3HDA P;  2RJQ A;  3EHX A;  3ZUK A;  1BKC E;  2TCL A;  1ZXV A;  4ON1 A;  3VTG A;  4IN9 A;  1GO7 P;  4WKI A;  2JT5 A;  3ZVS A;  1ZXC A;  5I43 A;  4IJO A;  1ROS A;  2OW9 A;  4CTH A;  1BM6 A;  1OM8 A;  1AKL A;  2CKI A;  1CAQ A;  3OHO A;  4FVL A;  3LUN A;  3BA0 A;  4DD8 A;  1ATL A;  3P24 A;  1C3I A;  1AST A;  1PWP A;  4Q1L A;  2MZH A;  1PWV A;  3CKI A;  3SHI A;  1G12 A;  1BUV M;  1XUC A;  2WO9 A;  5I4O A;  3EDG A;  3TSK A;  1SRP A;  4H76 A;  1XUD A;  3KME A;  966C A;  456C A;  5CZM A;  4J4M A;  3WV3 A;  1QJJ A;  4HMA A;  5L79 A;  3N2V A;  1PWW A;  1QIA A;  1PWU A;  4I35 A;  3U1R A;  2MZE A;  1IAD A;  4QKZ A;  2ERO A;  3EWJ A;  2O36 A;  4I03 A;  1FLS A;  5BPA A;  1KUG A;  1RMZ A;  3HB2 P;  2PJT A;  1GKC A;  3Q2H A;  2J0T A;  2OXU A;  1QIB A;  4WZV A;  2W0D A;  1OS9 A;  1IAG A;  1ZS0 A;  1BSW A;  3I7I A;  5D2B A;  1I76 A;  3N2U A;  4WK7 A;  1K7G A;  2N8R A;  1KBC A;  1R54 A;  5B5O A;  4PKR A;  3HDB A;  4GWM A;  3P1V A;  2YIG A;  1KAP P;  4PKS A;  3WV1 A;  1SU3 A;  3VI1 A;  4AXQ A;  1ND1 A;  1G49 A;  4A3W A;  2X3B A;  1L6J A;  1PWQ A;  3HBV P;  1AYK A;  1XUR A;  3K7L A;  4H49 A;  1YOU A;  2JNP A;  1XFZ A;  1Y0V A;  2MZI A;  4FU4 A;  1OS2 A;  2MLS A;  1GXD A;  1QIC A;  3WV2 A;  1IAE A;  4A7B A;  3DWB A;  1HFC A;  2OW0 A;  5CUH A;  3LGP A;  4XCT A;  1KUH A;  3G5C A;  3K7N A;  2X3C A;  2HU6 A;  3HY7 A;  1ZVX A;  1A86 A;  3LKA A;  3DSL A;  2OY4 A;  3KWV C;  3TT4 A;  1B8Y A;  1GKD A;  2DW2 A;  4R3V A;  2D1N A;  4GWN A;  1AF0 A;  1SAT A;  4XM8 A;  2OVZ A;  3DPE A;  2Z2D A;  1I1I P;  3KRY A;  1GE7 A;  2MLR A;  2DDF A;  2X7M A;  3EDI A;  2POJ A;  1MMR A;  1KUI A;  3MA2 A;  1JH1 A;  1K7Q A;  5I2Z A;  1USN A;  2JSD A;  3AYU A;  2A8H A;  2OW2 A;  1CIZ A;  1MMB A;  1G9K A;  5D1S A;  3AIG A;  2XS4 A;  1CXV A;  3B8Z A;  3NX7 A;  4XBH A;  1D7X A;  3LMC A;  5D7W A;  1C8T A;  1OM7 A;  3LQB A;  5D1T A;  1IAA A;  3LE9 A;  1BUD A;  1JJ9 A;  1H71 P;  1SLN A;  3LUM A;  1JIW P;  1WNI A;  1HY7 A;  2OI0 A;  4FXY P;  1HOV A;  1KUK A;  2FV5 A;  1R1J A;  5L7F A;  1XFX A;  3LIL A;  1SMP A;  1QUA A;  3EHY A;  1BKC A;  2K9C A;  2X3A A;  2W14 A;  4H2E A;  4PKU A;  1GE5 A;  1RM8 A;  4JA1 A;  4PKW A;  3HY9 A;  3HYG A;  4WF6 A;  5H8X A;  1JKY A;  4H84 A;  2DDY A;  2ERQ A;  1XFU A;  4H1Q A;  4H30 A;  2DW0 A;  4PKV A;  2FV9 A;  4IUW A;  4EFS A;  5B5P A;  3KEC A;  5LAB A;  5JMY A;  2I47 A;  5D1U A;  1JAN A;  1UTT A;  2SRT A;  1A85 A;  2O3E A;  3I7G A;  1D5J A;  1DTH A;  1CQR A;  1XFY A;  1R1H A;  1CGF A;  1CGE A;  3HBU P;  3OHL A;  4L63 A;  3KHI A;  1Y8J A;  4WKE A;  2V4B A;  3F1A A;  1FM1 A;  3RTS A;  2CLT A;  3O2X A;  1CK7 A;  1B3D A;  4L6T A;  2W13 A;  3LQ0 A;  3LJG A;  1G05 A;  1OM6 A;  1S4B P;  3B92 A;  1BQO A;  1ZP5 A;  2OXZ A;  4JIJ A;  2YB9 A;  3DPF A;  3LJT A;  3KMC A;  2D1O A;  4ZR5 A;  1Z3J A; 
#chains in the Genus database with same CATH topology
 1YQY A;  2WO8 A;  4XM6 A;  1MNC A;  2XS3 A;  2Y6C A;  2DW1 A;  3TVC A;  4HX3 A;  5D3C A;  1KUF A;  2Y6D A;  4AYK A;  1OMJ A;  1BKC I;  3LK8 A;  3EDH A;  2AIG P;  1DMT A;  4DV8 A;  1O0Q A;  1FBL A;  1UEA A;  3L0V A;  1D8F A;  3DL1 A;  5I0L A;  1C7K A;  2OXW A;  1ZTQ A;  4PKT A;  1JK3 A;  1R55 A;  3LJZ A;  3V96 B;  4FXQ A;  1O0T A;  4JPA A;  3Q2G A;  1XFV A;  3E8R A;  4PKQ A;  3G42 A;  1BQQ M;  4JP4 A;  5BOY A;  5I12 A;  1EB6 A;  1UMT A;  3F18 A;  1JAP A;  1JAO A;  4G0D A;  3F15 A;  4ILW D;  1R1I A;  1YCM A;  1Q3A A;  4AUO A;  1JIZ A;  5I3M A;  4GR8 A;  3AYK A;  3F17 A;  2ERP A;  4GF1 A;  1YP1 A;  1HTD A;  3L0T A;  1BZS A;  4GR0 A;  1CGL A;  1UTZ A;  2QPJ A;  2YUF A;  4H3X A;  2OZR A;  2JT6 A;  3ZXH A;  4AIG A;  830C A;  1QJI A;  2WOA A;  2OVX A;  3LIK A;  1GO8 P;  3RTT A;  2E2D A;  4DF9 A;  3DNG A;  1IAB A;  2W12 A;  4GR3 A;  1MMP A;  1J7N A;  1HFS A;  4L19 A;  3DTE A;  2JIH A;  3B2Z A;  2OY2 A;  4H82 A;  1IAC A;  1K7I A;  1OO9 A;  2E3X A;  3EDZ A;  3UVC A;  1JAQ A;  2AYK A;  4XM7 A;  5CXA A;  2K2G A;  1XFW A;  2USN A;  3USN A;  4DPE A;  2OW1 A;  1EUB A;  3O64 A;  4GUY A;  1G4K A;  1BIW A;  1GE6 A;  1D8M A;  3KEJ A;  1EAK A;  1I73 A;  3F16 A;  1MMQ A;  3F19 A;  4GQL A;  1SLM A;  3LIR A;  5BOT A;  3KEK A;  2W15 A;  4JQG A;  3ELM A;  2J83 A;  1Y93 A;  2L0R A;  2RJP A;  1HV5 A;  1UMS A;  4G9L A;  3GBO A;  2KRJ A;  3LEA A;  3TS4 A;  3HDA P;  2RJQ A;  3EHX A;  3ZUK A;  1BKC E;  2TCL A;  1ZXV A;  4ON1 A;  3VTG A;  4IN9 A;  1GO7 P;  4WKI A;  2JT5 A;  3ZVS A;  1ZXC A;  5I43 A;  4IJO A;  1ROS A;  2OW9 A;  4CTH A;  1BM6 A;  1OM8 A;  3DTK A;  1AKL A;  2CKI A;  1CAQ A;  3OHO A;  4FVL A;  3LUN A;  3BA0 A;  4DD8 A;  1ATL A;  3P24 A;  1C3I A;  1AST A;  1PWP A;  4Q1L A;  2MZH A;  1PWV A;  3CKI A;  3SHI A;  1G12 A;  1BUV M;  1XUC A;  2WO9 A;  5I4O A;  3EDG A;  3TSK A;  1SRP A;  4H76 A;  1XUD A;  3KME A;  4L7A A;  966C A;  456C A;  5CZM A;  4J4M A;  3WV3 A;  1QJJ A;  4HMA A;  5L79 A;  3DTI A;  3N2V A;  1PWW A;  1QIA A;  1PWU A;  4I35 A;  3U1R A;  2MZE A;  1IAD A;  4QKZ A;  2ERO A;  3EWJ A;  2O36 A;  4I03 A;  1FLS A;  5BPA A;  1KUG A;  1RMZ A;  3HB2 P;  2PJT A;  1GKC A;  3Q2H A;  2J0T A;  2OXU A;  1QIB A;  4WZV A;  2W0D A;  1OS9 A;  1IAG A;  1ZS0 A;  1BSW A;  3I7I A;  5D2B A;  1I76 A;  3N2U A;  4WK7 A;  1K7G A;  2N8R A;  1KBC A;  1R54 A;  5B5O A;  4PKR A;  3HDB A;  4GWM A;  3P1V A;  2YIG A;  1KAP P;  4PKS A;  3WV1 A;  1SU3 A;  3VI1 A;  4AXQ A;  1ND1 A;  1G49 A;  4A3W A;  2X3B A;  1L6J A;  1PWQ A;  3HBV P;  1AYK A;  1XUR A;  3K7L A;  4H49 A;  1YOU A;  2JNP A;  1XFZ A;  1Y0V A;  2MZI A;  4FU4 A;  1OS2 A;  2MLS A;  1GXD A;  1QIC A;  3WV2 A;  1IAE A;  4A7B A;  3DWB A;  1HFC A;  2OW0 A;  5CUH A;  3LGP A;  4XCT A;  1KUH A;  3G5C A;  3K7N A;  2X3C A;  2HU6 A;  3HY7 A;  1ZVX A;  1A86 A;  3LKA A;  3DSL A;  1XM5 A;  2OY4 A;  3KWV C;  3TT4 A;  1B8Y A;  1GKD A;  2DW2 A;  4R3V A;  2D1N A;  4GWN A;  1AF0 A;  1SAT A;  4XM8 A;  2OVZ A;  3DPE A;  2Z2D A;  1I1I P;  3KRY A;  1GE7 A;  2MLR A;  2DDF A;  2X7M A;  3EDI A;  2POJ A;  1MMR A;  1KUI A;  3MA2 A;  1JH1 A;  1K7Q A;  5I2Z A;  1USN A;  2JSD A;  3AYU A;  2A8H A;  2OW2 A;  1CIZ A;  1MMB A;  1G9K A;  5D1S A;  3AIG A;  2XS4 A;  1CXV A;  3B8Z A;  3NX7 A;  4XBH A;  1D7X A;  3LMC A;  5D7W A;  1C8T A;  1OM7 A;  3LQB A;  5D1T A;  1IAA A;  3LE9 A;  1BUD A;  1JJ9 A;  1H71 P;  1SLN A;  3LUM A;  1JIW P;  1WNI A;  1HY7 A;  2OI0 A;  4FXY P;  1HOV A;  1KUK A;  2FV5 A;  1R1J A;  5L7F A;  1XFX A;  3LIL A;  1SMP A;  1QUA A;  3EHY A;  1BKC A;  2K9C A;  2X3A A;  2W14 A;  4H2E A;  4PKU A;  1GE5 A;  1RM8 A;  4JA1 A;  4PKW A;  3HY9 A;  3HYG A;  4WF6 A;  5H8X A;  1JKY A;  4H84 A;  2DDY A;  2ERQ A;  1XFU A;  4H1Q A;  4H30 A;  2DW0 A;  4PKV A;  2FV9 A;  4IUW A;  4EFS A;  5B5P A;  3KEC A;  5LAB A;  5JMY A;  2I47 A;  5D1U A;  1JAN A;  1UTT A;  2SRT A;  1A85 A;  2O3E A;  3I7G A;  1TVI A;  1D5J A;  1DTH A;  1CQR A;  1XFY A;  1XAX A;  1R1H A;  1CGF A;  1CGE A;  3HBU P;  3OHL A;  4L63 A;  1OZ9 A;  3KHI A;  1Y8J A;  4WKE A;  2V4B A;  3F1A A;  1FM1 A;  3RTS A;  2CLT A;  3O2X A;  1CK7 A;  1B3D A;  4L6T A;  2W13 A;  3LQ0 A;  3LJG A;  1G05 A;  1OM6 A;  1S4B P;  3B92 A;  1BQO A;  1ZP5 A;  2OXZ A;  4JIJ A;  2YB9 A;  3DPF A;  3LJT A;  3KMC A;  2D1O A;  4ZR5 A;  1Z3J A; 
#chains in the Genus database with same CATH homology
 1YQY A;  2WO8 A;  4XM6 A;  1MNC A;  2XS3 A;  2Y6C A;  2DW1 A;  3TVC A;  4HX3 A;  5D3C A;  1KUF A;  2Y6D A;  4AYK A;  1OMJ A;  1BKC I;  3LK8 A;  3EDH A;  2AIG P;  1DMT A;  4DV8 A;  1O0Q A;  1FBL A;  1UEA A;  3L0V A;  1D8F A;  3DL1 A;  5I0L A;  1C7K A;  2OXW A;  1ZTQ A;  4PKT A;  1JK3 A;  1R55 A;  3LJZ A;  3V96 B;  4FXQ A;  1O0T A;  4JPA A;  3Q2G A;  1XFV A;  3E8R A;  4PKQ A;  3G42 A;  1BQQ M;  4JP4 A;  5BOY A;  5I12 A;  1EB6 A;  1UMT A;  3F18 A;  1JAP A;  1JAO A;  4G0D A;  3F15 A;  4ILW D;  1R1I A;  1YCM A;  1Q3A A;  4AUO A;  1JIZ A;  5I3M A;  4GR8 A;  3AYK A;  3F17 A;  2ERP A;  4GF1 A;  1YP1 A;  1HTD A;  3L0T A;  1BZS A;  4GR0 A;  1CGL A;  1UTZ A;  2QPJ A;  2YUF A;  4H3X A;  2OZR A;  2JT6 A;  3ZXH A;  4AIG A;  830C A;  1QJI A;  2WOA A;  2OVX A;  3LIK A;  1GO8 P;  3RTT A;  2E2D A;  4DF9 A;  3DNG A;  1IAB A;  2W12 A;  4GR3 A;  1MMP A;  1J7N A;  1HFS A;  4L19 A;  3DTE A;  2JIH A;  3B2Z A;  2OY2 A;  4H82 A;  1IAC A;  1K7I A;  1OO9 A;  2E3X A;  3EDZ A;  3UVC A;  1JAQ A;  2AYK A;  4XM7 A;  5CXA A;  2K2G A;  1XFW A;  2USN A;  3USN A;  4DPE A;  2OW1 A;  1EUB A;  3O64 A;  4GUY A;  1G4K A;  1BIW A;  1GE6 A;  1D8M A;  3KEJ A;  1EAK A;  1I73 A;  3F16 A;  1MMQ A;  3F19 A;  4GQL A;  1SLM A;  3LIR A;  5BOT A;  3KEK A;  2W15 A;  4JQG A;  3ELM A;  2J83 A;  1Y93 A;  2L0R A;  2RJP A;  1HV5 A;  1UMS A;  4G9L A;  3GBO A;  2KRJ A;  3LEA A;  3TS4 A;  3HDA P;  2RJQ A;  3EHX A;  3ZUK A;  1BKC E;  2TCL A;  1ZXV A;  4ON1 A;  3VTG A;  4IN9 A;  1GO7 P;  4WKI A;  2JT5 A;  3ZVS A;  1ZXC A;  5I43 A;  4IJO A;  1ROS A;  2OW9 A;  4CTH A;  1BM6 A;  1OM8 A;  3DTK A;  1AKL A;  2CKI A;  1CAQ A;  3OHO A;  4FVL A;  3LUN A;  3BA0 A;  4DD8 A;  1ATL A;  3P24 A;  1C3I A;  1AST A;  1PWP A;  4Q1L A;  2MZH A;  1PWV A;  3CKI A;  3SHI A;  1G12 A;  1BUV M;  1XUC A;  2WO9 A;  5I4O A;  3EDG A;  3TSK A;  1SRP A;  4H76 A;  1XUD A;  3KME A;  4L7A A;  966C A;  456C A;  5CZM A;  4J4M A;  3WV3 A;  1QJJ A;  4HMA A;  5L79 A;  3DTI A;  3N2V A;  1PWW A;  1QIA A;  1PWU A;  4I35 A;  3U1R A;  2MZE A;  1IAD A;  4QKZ A;  2ERO A;  3EWJ A;  2O36 A;  4I03 A;  1FLS A;  5BPA A;  1KUG A;  1RMZ A;  3HB2 P;  2PJT A;  1GKC A;  3Q2H A;  2J0T A;  2OXU A;  1QIB A;  4WZV A;  2W0D A;  1OS9 A;  1IAG A;  1ZS0 A;  1BSW A;  3I7I A;  5D2B A;  1I76 A;  3N2U A;  4WK7 A;  1K7G A;  2N8R A;  1KBC A;  1R54 A;  5B5O A;  4PKR A;  3HDB A;  4GWM A;  3P1V A;  2YIG A;  1KAP P;  4PKS A;  3WV1 A;  1SU3 A;  3VI1 A;  4AXQ A;  1ND1 A;  1G49 A;  4A3W A;  2X3B A;  1L6J A;  1PWQ A;  3HBV P;  1AYK A;  1XUR A;  3K7L A;  4H49 A;  1YOU A;  2JNP A;  1XFZ A;  1Y0V A;  2MZI A;  4FU4 A;  1OS2 A;  2MLS A;  1GXD A;  1QIC A;  3WV2 A;  1IAE A;  4A7B A;  3DWB A;  1HFC A;  2OW0 A;  5CUH A;  3LGP A;  4XCT A;  1KUH A;  3G5C A;  3K7N A;  2X3C A;  2HU6 A;  3HY7 A;  1ZVX A;  1A86 A;  3LKA A;  3DSL A;  2OY4 A;  3KWV C;  3TT4 A;  1B8Y A;  1GKD A;  2DW2 A;  4R3V A;  2D1N A;  4GWN A;  1AF0 A;  1SAT A;  4XM8 A;  2OVZ A;  3DPE A;  2Z2D A;  1I1I P;  3KRY A;  1GE7 A;  2MLR A;  2DDF A;  2X7M A;  3EDI A;  2POJ A;  1MMR A;  1KUI A;  3MA2 A;  1JH1 A;  1K7Q A;  5I2Z A;  1USN A;  2JSD A;  3AYU A;  2A8H A;  2OW2 A;  1CIZ A;  1MMB A;  1G9K A;  5D1S A;  3AIG A;  2XS4 A;  1CXV A;  3B8Z A;  3NX7 A;  4XBH A;  1D7X A;  3LMC A;  5D7W A;  1C8T A;  1OM7 A;  3LQB A;  5D1T A;  1IAA A;  3LE9 A;  1BUD A;  1JJ9 A;  1H71 P;  1SLN A;  3LUM A;  1JIW P;  1WNI A;  1HY7 A;  2OI0 A;  4FXY P;  1HOV A;  1KUK A;  2FV5 A;  1R1J A;  5L7F A;  1XFX A;  3LIL A;  1SMP A;  1QUA A;  3EHY A;  1BKC A;  2K9C A;  2X3A A;  2W14 A;  4H2E A;  4PKU A;  1GE5 A;  1RM8 A;  4JA1 A;  4PKW A;  3HY9 A;  3HYG A;  4WF6 A;  5H8X A;  1JKY A;  4H84 A;  2DDY A;  2ERQ A;  1XFU A;  4H1Q A;  4H30 A;  2DW0 A;  4PKV A;  2FV9 A;  4IUW A;  4EFS A;  5B5P A;  3KEC A;  5LAB A;  5JMY A;  2I47 A;  5D1U A;  1JAN A;  1UTT A;  2SRT A;  1A85 A;  2O3E A;  3I7G A;  1D5J A;  1DTH A;  1CQR A;  1XFY A;  1R1H A;  1CGF A;  1CGE A;  3HBU P;  3OHL A;  4L63 A;  3KHI A;  1Y8J A;  4WKE A;  2V4B A;  3F1A A;  1FM1 A;  3RTS A;  2CLT A;  3O2X A;  1CK7 A;  1B3D A;  4L6T A;  2W13 A;  3LQ0 A;  3LJG A;  1G05 A;  1OM6 A;  1S4B P;  3B92 A;  1BQO A;  1ZP5 A;  2OXZ A;  4JIJ A;  2YB9 A;  3DPF A;  3LJT A;  3KMC A;  2D1O A;  4ZR5 A;  1Z3J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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