4H49A

Crystal structure of the catalytic domain of mmp-12 in complex with a twin inhibitor.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallization of bi-functional ligand protein complexes.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 49
structure length 159
sequence length 159
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-09-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4h49A00
3LUMA 3Q2GA 1GE5A 1I76A 2DW2A 1ZS0A 1AKLA 1HY7A 1R54A 2Y6CA 2JT5A 4PKVA 2USNA 1ROSA 5B5PA 1HTDA 4DD8A 1FLSA 2W15A 5D1TA 2K2GA 4L6TA 2MLRA 2RJQA 4G0DA 2E3XA 5I43A 3U1RA 2A8HA 3EDIA 1H71P 1OM6A 1JAOA 5CZMA 1L6JA 1ND1A 1IACA 5I3MA 3RTSA 4IN9A 1BUDA 1USNA 5D3CA 1QICA 1OS9A 2OW9A 1GKDA 4H76A 3G42A 4PKRA 1MMPA 1R1JA 2OY4A 3TS4A 1C3IA 4ON1A 1HV5A 3KEJA 3LQ0A 4XM7A 3I7GA 1I1IP 2OXUA 1IABA 1UTZA 3ZVSA 1SU3A 1MMRA 2OXWA 1PWWA 1IADA 2OZRA 1BKCI 2KRJA 3N2VA 2OW2A 1CGEA 4JIJA 3UVCA 2AIGP 2JSDA 5BOYA 1KUHA 2X3AA 3DL1A 1ZXVA 4XM6A 4WKIA 4H84A 2W14A 1MMBA 1C8TA 1KBCA 1JAPA 1CXVA 5L79A 1JKYA 3WV1A 4H3XA 1G12A 4J4MA 1YOUA 1GKCA 1UMSA 4WF6A 3Q2HA 3K7LA 3DSLA 3LILA 2DDYA 4WK7A 4GR3A 1CGFA 2MZHA 4PKTA 2OVZA 3TVCA 1Y93A 1MNCA 1SLMA 1G9KA 3AYKA 2DW1A 4DF9A 4L19A 2O36A 1ZP5A 3E8RA 5B5OA 1AF0A 2D1NA 1XFZA 2RJPA 2K9CA 4G9LA 4DPEA 2OY2A 2OXZA 1D5JA 5BPAA 3VI1A 2J83A 1BM6A 1JAQA 1JH1A 1OS2A 1KUIA 2PJTA 1SATA 1XFYA 2OW1A 966CA 4FU4A 2W13A 1YP1A 1ZTQA 1BQQM 4HMAA 1BZSA 3HB2P 1UMTA 5LABA 4JA1A 2W12A 1RMZA 5I0LA 1SLNA 2DDFA 1ZVXA 1R55A 4AIGA 1B3DA 4EFSA 1Z3JA 5I12A 1GO7P 3F15A 5I4OA 2OI0A 1QIBA 1BQOA 1BIWA 3DWBA 2X3BA 1EAKA 3O2XA 2FV9A 3N2UA 3F18A 3BA0A 4FVLA 1JIZA 830CA 4PKUA 3LMCA 3EDZA 1JANA 2L0RA 456CA 2X7MA 1D7XA 3NX7A 3OHOA 2FV5A 4PKWA 1GE6A 3ELMA 2WOAA 4AUOA 3V96B 1YQYA 1PWQA 4H49A 5CUHA 3LGPA 4I03A 4JPAA 4GF1A 3F1AA 2HU6A 1KAPP 1GO8P 2Y6DA 1XFUA 2V4BA 1ATLA 1BSWA 1XFXA 2E2DA 5L7FA 1O0QA 3P24A 1DMTA 1J7NA 1OMJA 2QPJA 2CLTA 1O0TA 3P1VA 1ASTA 3B8ZA 3EDGA 4AYKA 1KUGA 4AXQA 3EHYA 2CKIA 3B92A 1KUKA 5JMYA 1R1IA 3HBVP 4GQLA 1K7QA 2OW0A 3LIKA 1IAAA 3OHLA 3K7NA 3HDAP 3AIGA 4JQGA 4FXQA 3LEAA 3HBUP 2DW0A 1G05A 3TSKA 3KMEA 1QIAA 3DPEA 1AYKA 2Z2DA 4A3WA 2JNPA 3LJTA 4CTHA 4XBHA 2SRTA 1D8FA 5CXAA 1XUCA 3LQBA 3F16A 1K7GA 4XCTA 3MA2A 4ILWD 2W0DA 4GWNA 5H8XA 1BKCE 2J0TA 1K7IA 4GUYA 3WV2A 3F17A 1GE7A 2D1OA 4R3VA 1XURA 2O3EA 1A85A 1KUFA 4I35A 3LE9A 1CAQA 1YCMA 3HY7A 1CK7A 4DV8A 1MMQA 3ZXHA 4HX3A 3KEKA 4GWMA 1BUVM 3KWVC 4ZR5A 3ZUKA 1XUDA 3L0VA 1OO9A 1Y0VA 4PKSA 1IAEA 1HFSA 4FXYP 5I2ZA 2JT6A 1UEAA 1Q3AA 2MZIA 5D7WA 1JJ9A 1OM8A 2WO8A 1EUBA 3KHIA 1GXDA 3EHXA 4H1QA 2X3CA 2OVXA 4GR8A 1A86A 1HFCA 3VTGA 1D8MA 2POJA 4IUWA 2XS3A 3RTTA 1CIZA 1Y8JA 2MLSA 3EWJA 1PWUA 1B8YA 1FBLA 3DPFA 1DTHA 2WO9A 1G49A 3AYUA 2TCLA 4L63A 1UTTA 4Q1LA 2YIGA 3LIRA 3F19A 1CGLA 5D2BA 2JIHA 2EROA 1PWPA 1QJJA 3USNA 2I47A 3B2ZA 4A7BA 1XFWA 1BKCA 4H2EA 3LKAA 4IJOA 1PWVA 3HDBA 4WZVA 1CQRA 3EDHA 1ZXCA 1I73A 1QUAA 3KECA 3TT4A 3I7IA 5D1UA 1SRPA 1R1HA 4QKZA 1JIWP 1OM7A 1IAGA 2AYKA 3CKIA 2YB9A 2XS4A 4PKQA 3L0TA 3LUNA 4GR0A 3WV3A 4XM8A 1QJIA 2ERPA 5BOTA 1C7KA 1G4KA 1JK3A 3LJZA 2MZEA 3HY9A 2N8RA 3O64A 4H82A 1S4BP 1WNIA 1RM8A 3LJGA 1FM1A 3HYGA 3KRYA 3GBOA 1HOVA 5D1SA 2ERQA 4H30A 1SMPA 4WKEA 3G5CA 3KMCA 1EB6A 3LK8A 1XFVA 3DNGA 3SHIA 4JP4A
chains in the Genus database with same CATH superfamily
3LUMA 3Q2GA 1GE5A 1I76A 2DW2A 1ZS0A 1AKLA 1OZ9A 1HY7A 1R54A 2Y6CA 2JT5A 4PKVA 2USNA 1ROSA 5B5PA 1HTDA 4DD8A 4L7AA 1FLSA 2W15A 5D1TA 2K2GA 4L6TA 2MLRA 2RJQA 4G0DA 2E3XA 5I43A 3U1RA 2A8HA 3EDIA 1H71P 1OM6A 1JAOA 5CZMA 1L6JA 1ND1A 1IACA 5I3MA 3RTSA 4IN9A 1BUDA 1USNA 5D3CA 1QICA 1OS9A 2OW9A 1GKDA 4H76A 3G42A 4PKRA 1MMPA 1R1JA 2OY4A 3TS4A 1C3IA 4ON1A 1HV5A 3KEJA 3LQ0A 4XM7A 3I7GA 1I1IP 2OXUA 1IABA 1UTZA 3ZVSA 1SU3A 1MMRA 2OXWA 1PWWA 1IADA 2OZRA 1BKCI 2KRJA 3N2VA 2OW2A 1CGEA 4JIJA 3UVCA 2AIGP 2JSDA 5BOYA 1KUHA 2X3AA 3DL1A 1ZXVA 4XM6A 4WKIA 4H84A 2W14A 1MMBA 1C8TA 1KBCA 1JAPA 1CXVA 5L79A 1JKYA 3WV1A 4H3XA 1G12A 4J4MA 1YOUA 1GKCA 1UMSA 4WF6A 3Q2HA 3K7LA 3DSLA 3LILA 2DDYA 4WK7A 4GR3A 1CGFA 2MZHA 4PKTA 2OVZA 3TVCA 1Y93A 1MNCA 1SLMA 1G9KA 3AYKA 2DW1A 4DF9A 4L19A 2O36A 1ZP5A 3E8RA 5B5OA 1AF0A 2D1NA 1XFZA 2RJPA 2K9CA 4G9LA 4DPEA 2OY2A 2OXZA 1D5JA 5BPAA 3VI1A 2J83A 1BM6A 1JAQA 1JH1A 1OS2A 1KUIA 2PJTA 1SATA 1XFYA 2OW1A 966CA 4FU4A 2W13A 1YP1A 1ZTQA 1BQQM 4HMAA 1BZSA 3HB2P 1UMTA 5LABA 4JA1A 2W12A 1RMZA 5I0LA 1SLNA 2DDFA 1ZVXA 1R55A 4AIGA 1B3DA 4EFSA 1Z3JA 5I12A 1GO7P 3F15A 5I4OA 2OI0A 1QIBA 1BQOA 1BIWA 3DWBA 2X3BA 1EAKA 3O2XA 2FV9A 3N2UA 3F18A 3BA0A 4FVLA 1JIZA 830CA 4PKUA 3LMCA 3EDZA 1JANA 2L0RA 456CA 2X7MA 1D7XA 3NX7A 3OHOA 2FV5A 4PKWA 1GE6A 3ELMA 2WOAA 4AUOA 3V96B 1YQYA 1PWQA 4H49A 5CUHA 3LGPA 4I03A 4JPAA 4GF1A 3F1AA 2HU6A 1KAPP 1GO8P 2Y6DA 1XFUA 2V4BA 1ATLA 1BSWA 1XFXA 2E2DA 5L7FA 1O0QA 3P24A 1DMTA 1J7NA 1OMJA 2QPJA 2CLTA 1O0TA 3P1VA 1ASTA 3B8ZA 3EDGA 1TVIA 4AYKA 1KUGA 4AXQA 3EHYA 2CKIA 3B92A 1KUKA 5JMYA 1R1IA 3HBVP 3DTEA 4GQLA 1K7QA 2OW0A 3LIKA 1IAAA 3OHLA 3K7NA 3HDAP 3AIGA 1XAXA 4JQGA 4FXQA 3LEAA 3HBUP 2DW0A 1G05A 3TSKA 3KMEA 1QIAA 3DPEA 1AYKA 2Z2DA 4A3WA 2JNPA 3LJTA 4CTHA 4XBHA 2SRTA 1D8FA 5CXAA 1XUCA 3LQBA 3F16A 1K7GA 4XCTA 3MA2A 4ILWD 2W0DA 4GWNA 3DTKA 5H8XA 1BKCE 2J0TA 1K7IA 4GUYA 3WV2A 3F17A 1GE7A 2D1OA 4R3VA 1XURA 2O3EA 1A85A 1KUFA 4I35A 3LE9A 1CAQA 1YCMA 3HY7A 1CK7A 4DV8A 1MMQA 3ZXHA 4HX3A 3KEKA 4GWMA 1BUVM 3KWVC 4ZR5A 3ZUKA 1XUDA 3L0VA 1OO9A 1Y0VA 4PKSA 1IAEA 1HFSA 4FXYP 5I2ZA 2JT6A 1UEAA 1Q3AA 2MZIA 5D7WA 1JJ9A 1OM8A 2WO8A 1EUBA 3KHIA 1GXDA 3EHXA 4H1QA 2X3CA 2OVXA 4GR8A 1A86A 1HFCA 3VTGA 1D8MA 2POJA 4IUWA 2XS3A 3RTTA 1CIZA 1Y8JA 2MLSA 3EWJA 1PWUA 1B8YA 1FBLA 3DPFA 1DTHA 2WO9A 1G49A 3AYUA 2TCLA 4L63A 1UTTA 4Q1LA 2YIGA 3LIRA 3F19A 1CGLA 3DTIA 5D2BA 2JIHA 2EROA 1PWPA 1QJJA 3USNA 2I47A 3B2ZA 4A7BA 1XFWA 1BKCA 4H2EA 3LKAA 4IJOA 1PWVA 3HDBA 4WZVA 1CQRA 3EDHA 1ZXCA 1I73A 1QUAA 3KECA 3TT4A 3I7IA 1XM5A 5D1UA 1SRPA 1R1HA 4QKZA 1JIWP 1OM7A 1IAGA 2AYKA 3CKIA 2YB9A 2XS4A 4PKQA 3L0TA 3LUNA 4GR0A 3WV3A 4XM8A 1QJIA 2ERPA 5BOTA 2YUFA 1C7KA 1G4KA 1JK3A 3LJZA 2MZEA 3HY9A 2N8RA 3O64A 4H82A 1S4BP 1WNIA 1RM8A 3LJGA 1FM1A 3HYGA 3KRYA 3GBOA 1HOVA 5D1SA 2ERQA 4H30A 1SMPA 4WKEA 3G5CA 3KMCA 1EB6A 3LK8A 1XFVA 3DNGA 3SHIA 4JP4A
chains in the Genus database with same CATH topology
3LUMA 3Q2GA 1GE5A 1I76A 2DW2A 1ZS0A 1AKLA 1HY7A 1R54A 2Y6CA 2JT5A 4PKVA 2USNA 1ROSA 5B5PA 1HTDA 4DD8A 4L7AA 1FLSA 2W15A 5D1TA 2K2GA 4L6TA 2MLRA 2RJQA 4G0DA 2E3XA 5I43A 3U1RA 2A8HA 3EDIA 1H71P 1OM6A 1JAOA 5CZMA 1L6JA 1ND1A 1IACA 5I3MA 3RTSA 4IN9A 1BUDA 1USNA 5D3CA 1QICA 1OS9A 2OW9A 1GKDA 4H76A 3G42A 4PKRA 1MMPA 1R1JA 2OY4A 3TS4A 1C3IA 4ON1A 1HV5A 3KEJA 3LQ0A 4XM7A 3I7GA 1I1IP 2OXUA 1IABA 1UTZA 3ZVSA 1SU3A 1MMRA 2OXWA 1PWWA 1IADA 2OZRA 1BKCI 2KRJA 3N2VA 2OW2A 1CGEA 4JIJA 3UVCA 2AIGP 2JSDA 5BOYA 1KUHA 2X3AA 3DL1A 1ZXVA 4XM6A 4WKIA 4H84A 2W14A 1MMBA 1C8TA 1KBCA 1JAPA 1CXVA 5L79A 1JKYA 3WV1A 4H3XA 1G12A 4J4MA 1YOUA 1GKCA 1UMSA 4WF6A 3Q2HA 3K7LA 3DSLA 3LILA 2DDYA 4WK7A 4GR3A 1CGFA 2MZHA 4PKTA 2OVZA 3TVCA 1Y93A 1MNCA 1SLMA 1G9KA 3AYKA 2DW1A 4DF9A 4L19A 2O36A 1ZP5A 3E8RA 5B5OA 1AF0A 2D1NA 1XFZA 2RJPA 2K9CA 4G9LA 4DPEA 2OY2A 2OXZA 1D5JA 5BPAA 3VI1A 2J83A 1BM6A 1JAQA 1JH1A 1OS2A 1KUIA 2PJTA 1SATA 1XFYA 2OW1A 966CA 4FU4A 2W13A 1YP1A 1ZTQA 1BQQM 4HMAA 1BZSA 3HB2P 1UMTA 5LABA 4JA1A 2W12A 1RMZA 5I0LA 1SLNA 2DDFA 1ZVXA 1R55A 4AIGA 1B3DA 4EFSA 1Z3JA 5I12A 1GO7P 3F15A 5I4OA 2OI0A 1QIBA 1BQOA 1BIWA 3DWBA 2X3BA 1EAKA 3O2XA 2FV9A 3N2UA 3F18A 3BA0A 4FVLA 1JIZA 830CA 4PKUA 3LMCA 3EDZA 1JANA 2L0RA 456CA 2X7MA 1D7XA 3NX7A 3OHOA 2FV5A 4PKWA 1GE6A 3ELMA 2WOAA 4AUOA 3V96B 1YQYA 1PWQA 4H49A 5CUHA 3LGPA 4I03A 4JPAA 4GF1A 3F1AA 2HU6A 1KAPP 1GO8P 2Y6DA 1XFUA 2V4BA 1ATLA 1BSWA 1XFXA 2E2DA 5L7FA 1O0QA 3P24A 1DMTA 1J7NA 1OMJA 2QPJA 2CLTA 1O0TA 3P1VA 1ASTA 3B8ZA 3EDGA 4AYKA 1KUGA 4AXQA 3EHYA 2CKIA 3B92A 1KUKA 5JMYA 1R1IA 3HBVP 3DTEA 4GQLA 1K7QA 2OW0A 3LIKA 1IAAA 3OHLA 3K7NA 3HDAP 3AIGA 4JQGA 4FXQA 3LEAA 3HBUP 2DW0A 1G05A 3TSKA 3KMEA 1QIAA 3DPEA 1AYKA 2Z2DA 4A3WA 2JNPA 3LJTA 4CTHA 4XBHA 2SRTA 1D8FA 5CXAA 1XUCA 3LQBA 3F16A 1K7GA 4XCTA 3MA2A 4ILWD 2W0DA 4GWNA 3DTKA 5H8XA 1BKCE 2J0TA 1K7IA 4GUYA 3WV2A 3F17A 1GE7A 2D1OA 4R3VA 1XURA 2O3EA 1A85A 1KUFA 4I35A 3LE9A 1CAQA 1YCMA 3HY7A 1CK7A 4DV8A 1MMQA 3ZXHA 4HX3A 3KEKA 4GWMA 1BUVM 3KWVC 4ZR5A 3ZUKA 1XUDA 3L0VA 1OO9A 1Y0VA 4PKSA 1IAEA 1HFSA 4FXYP 5I2ZA 2JT6A 1UEAA 1Q3AA 2MZIA 5D7WA 1JJ9A 1OM8A 2WO8A 1EUBA 3KHIA 1GXDA 3EHXA 4H1QA 2X3CA 2OVXA 4GR8A 1A86A 1HFCA 3VTGA 1D8MA 2POJA 4IUWA 2XS3A 3RTTA 1CIZA 1Y8JA 2MLSA 3EWJA 1PWUA 1B8YA 1FBLA 3DPFA 1DTHA 2WO9A 1G49A 3AYUA 2TCLA 4L63A 1UTTA 4Q1LA 2YIGA 3LIRA 3F19A 1CGLA 3DTIA 5D2BA 2JIHA 2EROA 1PWPA 1QJJA 3USNA 2I47A 3B2ZA 4A7BA 1XFWA 1BKCA 4H2EA 3LKAA 4IJOA 1PWVA 3HDBA 4WZVA 1CQRA 3EDHA 1ZXCA 1I73A 1QUAA 3KECA 3TT4A 3I7IA 5D1UA 1SRPA 1R1HA 4QKZA 1JIWP 1OM7A 1IAGA 2AYKA 3CKIA 2YB9A 2XS4A 4PKQA 3L0TA 3LUNA 4GR0A 3WV3A 4XM8A 1QJIA 2ERPA 5BOTA 2YUFA 1C7KA 1G4KA 1JK3A 3LJZA 2MZEA 3HY9A 2N8RA 3O64A 4H82A 1S4BP 1WNIA 1RM8A 3LJGA 1FM1A 3HYGA 3KRYA 3GBOA 1HOVA 5D1SA 2ERQA 4H30A 1SMPA 4WKEA 3G5CA 3KMCA 1EB6A 3LK8A 1XFVA 3DNGA 3SHIA 4JP4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LUM A;  3Q2G A;  1GE5 A;  1I76 A;  2DW2 A;  1ZS0 A;  1AKL A;  1HY7 A;  1R54 A;  2Y6C A;  2JT5 A;  4PKV A;  2USN A;  1ROS A;  5B5P A;  1HTD A;  4DD8 A;  1FLS A;  2W15 A;  5D1T A;  2K2G A;  4L6T A;  2MLR A;  2RJQ A;  4G0D A;  2E3X A;  5I43 A;  3U1R A;  2A8H A;  3EDI A;  1H71 P;  1OM6 A;  1JAO A;  5CZM A;  1L6J A;  1ND1 A;  1IAC A;  5I3M A;  3RTS A;  4IN9 A;  1BUD A;  1USN A;  5D3C A;  1QIC A;  1OS9 A;  2OW9 A;  1GKD A;  4H76 A;  3G42 A;  4PKR A;  1MMP A;  1R1J A;  2OY4 A;  3TS4 A;  1C3I A;  4ON1 A;  1HV5 A;  3KEJ A;  3LQ0 A;  4XM7 A;  3I7G A;  1I1I P;  2OXU A;  1IAB A;  1UTZ A;  3ZVS A;  1SU3 A;  1MMR A;  2OXW A;  1PWW A;  1IAD A;  2OZR A;  1BKC I;  2KRJ A;  3N2V A;  2OW2 A;  1CGE A;  4JIJ A;  3UVC A;  2AIG P;  2JSD A;  5BOY A;  1KUH A;  2X3A A;  3DL1 A;  1ZXV A;  4XM6 A;  4WKI A;  4H84 A;  2W14 A;  1MMB A;  1C8T A;  1KBC A;  1JAP A;  1CXV A;  5L79 A;  1JKY A;  3WV1 A;  4H3X A;  1G12 A;  4J4M A;  1YOU A;  1GKC A;  1UMS A;  4WF6 A;  3Q2H A;  3K7L A;  3DSL A;  3LIL A;  2DDY A;  4WK7 A;  4GR3 A;  1CGF A;  2MZH A;  4PKT A;  2OVZ A;  3TVC A;  1Y93 A;  1MNC A;  1SLM A;  1G9K A;  3AYK A;  2DW1 A;  4DF9 A;  4L19 A;  2O36 A;  1ZP5 A;  3E8R A;  5B5O A;  1AF0 A;  2D1N A;  1XFZ A;  2RJP A;  2K9C A;  4G9L A;  4DPE A;  2OY2 A;  2OXZ A;  1D5J A;  5BPA A;  3VI1 A;  2J83 A;  1BM6 A;  1JAQ A;  1JH1 A;  1OS2 A;  1KUI A;  2PJT A;  1SAT A;  1XFY A;  2OW1 A;  966C A;  4FU4 A;  2W13 A;  1YP1 A;  1ZTQ A;  1BQQ M;  4HMA A;  1BZS A;  3HB2 P;  1UMT A;  5LAB A;  4JA1 A;  2W12 A;  1RMZ A;  5I0L A;  1SLN A;  2DDF A;  1ZVX A;  1R55 A;  4AIG A;  1B3D A;  4EFS A;  1Z3J A;  5I12 A;  1GO7 P;  3F15 A;  5I4O A;  2OI0 A;  1QIB A;  1BQO A;  1BIW A;  3DWB A;  2X3B A;  1EAK A;  3O2X A;  2FV9 A;  3N2U A;  3F18 A;  3BA0 A;  4FVL A;  1JIZ A;  830C A;  4PKU A;  3LMC A;  3EDZ A;  1JAN A;  2L0R A;  456C A;  2X7M A;  1D7X A;  3NX7 A;  3OHO A;  2FV5 A;  4PKW A;  1GE6 A;  3ELM A;  2WOA A;  4AUO A;  3V96 B;  1YQY A;  1PWQ A;  4H49 A;  5CUH A;  3LGP A;  4I03 A;  4JPA A;  4GF1 A;  3F1A A;  2HU6 A;  1KAP P;  1GO8 P;  2Y6D A;  1XFU A;  2V4B A;  1ATL A;  1BSW A;  1XFX A;  2E2D A;  5L7F A;  1O0Q A;  3P24 A;  1DMT A;  1J7N A;  1OMJ A;  2QPJ A;  2CLT A;  1O0T A;  3P1V A;  1AST A;  3B8Z A;  3EDG A;  4AYK A;  1KUG A;  4AXQ A;  3EHY A;  2CKI A;  3B92 A;  1KUK A;  5JMY A;  1R1I A;  3HBV P;  4GQL A;  1K7Q A;  2OW0 A;  3LIK A;  1IAA A;  3OHL A;  3K7N A;  3HDA P;  3AIG A;  4JQG A;  4FXQ A;  3LEA A;  3HBU P;  2DW0 A;  1G05 A;  3TSK A;  3KME A;  1QIA A;  3DPE A;  1AYK A;  2Z2D A;  4A3W A;  2JNP A;  3LJT A;  4CTH A;  4XBH A;  2SRT A;  1D8F A;  5CXA A;  1XUC A;  3LQB A;  3F16 A;  1K7G A;  4XCT A;  3MA2 A;  4ILW D;  2W0D A;  4GWN A;  5H8X A;  1BKC E;  2J0T A;  1K7I A;  4GUY A;  3WV2 A;  3F17 A;  1GE7 A;  2D1O A;  4R3V A;  1XUR A;  2O3E A;  1A85 A;  1KUF A;  4I35 A;  3LE9 A;  1CAQ A;  1YCM A;  3HY7 A;  1CK7 A;  4DV8 A;  1MMQ A;  3ZXH A;  4HX3 A;  3KEK A;  4GWM A;  1BUV M;  3KWV C;  4ZR5 A;  3ZUK A;  1XUD A;  3L0V A;  1OO9 A;  1Y0V A;  4PKS A;  1IAE A;  1HFS A;  4FXY P;  5I2Z A;  2JT6 A;  1UEA A;  1Q3A A;  2MZI A;  5D7W A;  1JJ9 A;  1OM8 A;  2WO8 A;  1EUB A;  3KHI A;  1GXD A;  3EHX A;  4H1Q A;  2X3C A;  2OVX A;  4GR8 A;  1A86 A;  1HFC A;  3VTG A;  1D8M A;  2POJ A;  4IUW A;  2XS3 A;  3RTT A;  1CIZ A;  1Y8J A;  2MLS A;  3EWJ A;  1PWU A;  1B8Y A;  1FBL A;  3DPF A;  1DTH A;  2WO9 A;  1G49 A;  3AYU A;  2TCL A;  4L63 A;  1UTT A;  4Q1L A;  2YIG A;  3LIR A;  3F19 A;  1CGL A;  5D2B A;  2JIH A;  2ERO A;  1PWP A;  1QJJ A;  3USN A;  2I47 A;  3B2Z A;  4A7B A;  1XFW A;  1BKC A;  4H2E A;  3LKA A;  4IJO A;  1PWV A;  3HDB A;  4WZV A;  1CQR A;  3EDH A;  1ZXC A;  1I73 A;  1QUA A;  3KEC A;  3TT4 A;  3I7I A;  5D1U A;  1SRP A;  1R1H A;  4QKZ A;  1JIW P;  1OM7 A;  1IAG A;  2AYK A;  3CKI A;  2YB9 A;  2XS4 A;  4PKQ A;  3L0T A;  3LUN A;  4GR0 A;  3WV3 A;  4XM8 A;  1QJI A;  2ERP A;  5BOT A;  1C7K A;  1G4K A;  1JK3 A;  3LJZ A;  2MZE A;  3HY9 A;  2N8R A;  3O64 A;  4H82 A;  1S4B P;  1WNI A;  1RM8 A;  3LJG A;  1FM1 A;  3HYG A;  3KRY A;  3GBO A;  1HOV A;  5D1S A;  2ERQ A;  4H30 A;  1SMP A;  4WKE A;  3G5C A;  3KMC A;  1EB6 A;  3LK8 A;  1XFV A;  3DNG A;  3SHI A;  4JP4 A; 
#chains in the Genus database with same CATH topology
 3LUM A;  3Q2G A;  1GE5 A;  1I76 A;  2DW2 A;  1ZS0 A;  1AKL A;  1OZ9 A;  1HY7 A;  1R54 A;  2Y6C A;  2JT5 A;  4PKV A;  2USN A;  1ROS A;  5B5P A;  1HTD A;  4DD8 A;  4L7A A;  1FLS A;  2W15 A;  5D1T A;  2K2G A;  4L6T A;  2MLR A;  2RJQ A;  4G0D A;  2E3X A;  5I43 A;  3U1R A;  2A8H A;  3EDI A;  1H71 P;  1OM6 A;  1JAO A;  5CZM A;  1L6J A;  1ND1 A;  1IAC A;  5I3M A;  3RTS A;  4IN9 A;  1BUD A;  1USN A;  5D3C A;  1QIC A;  1OS9 A;  2OW9 A;  1GKD A;  4H76 A;  3G42 A;  4PKR A;  1MMP A;  1R1J A;  2OY4 A;  3TS4 A;  1C3I A;  4ON1 A;  1HV5 A;  3KEJ A;  3LQ0 A;  4XM7 A;  3I7G A;  1I1I P;  2OXU A;  1IAB A;  1UTZ A;  3ZVS A;  1SU3 A;  1MMR A;  2OXW A;  1PWW A;  1IAD A;  2OZR A;  1BKC I;  2KRJ A;  3N2V A;  2OW2 A;  1CGE A;  4JIJ A;  3UVC A;  2AIG P;  2JSD A;  5BOY A;  1KUH A;  2X3A A;  3DL1 A;  1ZXV A;  4XM6 A;  4WKI A;  4H84 A;  2W14 A;  1MMB A;  1C8T A;  1KBC A;  1JAP A;  1CXV A;  5L79 A;  1JKY A;  3WV1 A;  4H3X A;  1G12 A;  4J4M A;  1YOU A;  1GKC A;  1UMS A;  4WF6 A;  3Q2H A;  3K7L A;  3DSL A;  3LIL A;  2DDY A;  4WK7 A;  4GR3 A;  1CGF A;  2MZH A;  4PKT A;  2OVZ A;  3TVC A;  1Y93 A;  1MNC A;  1SLM A;  1G9K A;  3AYK A;  2DW1 A;  4DF9 A;  4L19 A;  2O36 A;  1ZP5 A;  3E8R A;  5B5O A;  1AF0 A;  2D1N A;  1XFZ A;  2RJP A;  2K9C A;  4G9L A;  4DPE A;  2OY2 A;  2OXZ A;  1D5J A;  5BPA A;  3VI1 A;  2J83 A;  1BM6 A;  1JAQ A;  1JH1 A;  1OS2 A;  1KUI A;  2PJT A;  1SAT A;  1XFY A;  2OW1 A;  966C A;  4FU4 A;  2W13 A;  1YP1 A;  1ZTQ A;  1BQQ M;  4HMA A;  1BZS A;  3HB2 P;  1UMT A;  5LAB A;  4JA1 A;  2W12 A;  1RMZ A;  5I0L A;  1SLN A;  2DDF A;  1ZVX A;  1R55 A;  4AIG A;  1B3D A;  4EFS A;  1Z3J A;  5I12 A;  1GO7 P;  3F15 A;  5I4O A;  2OI0 A;  1QIB A;  1BQO A;  1BIW A;  3DWB A;  2X3B A;  1EAK A;  3O2X A;  2FV9 A;  3N2U A;  3F18 A;  3BA0 A;  4FVL A;  1JIZ A;  830C A;  4PKU A;  3LMC A;  3EDZ A;  1JAN A;  2L0R A;  456C A;  2X7M A;  1D7X A;  3NX7 A;  3OHO A;  2FV5 A;  4PKW A;  1GE6 A;  3ELM A;  2WOA A;  4AUO A;  3V96 B;  1YQY A;  1PWQ A;  4H49 A;  5CUH A;  3LGP A;  4I03 A;  4JPA A;  4GF1 A;  3F1A A;  2HU6 A;  1KAP P;  1GO8 P;  2Y6D A;  1XFU A;  2V4B A;  1ATL A;  1BSW A;  1XFX A;  2E2D A;  5L7F A;  1O0Q A;  3P24 A;  1DMT A;  1J7N A;  1OMJ A;  2QPJ A;  2CLT A;  1O0T A;  3P1V A;  1AST A;  3B8Z A;  3EDG A;  1TVI A;  4AYK A;  1KUG A;  4AXQ A;  3EHY A;  2CKI A;  3B92 A;  1KUK A;  5JMY A;  1R1I A;  3HBV P;  3DTE A;  4GQL A;  1K7Q A;  2OW0 A;  3LIK A;  1IAA A;  3OHL A;  3K7N A;  3HDA P;  3AIG A;  1XAX A;  4JQG A;  4FXQ A;  3LEA A;  3HBU P;  2DW0 A;  1G05 A;  3TSK A;  3KME A;  1QIA A;  3DPE A;  1AYK A;  2Z2D A;  4A3W A;  2JNP A;  3LJT A;  4CTH A;  4XBH A;  2SRT A;  1D8F A;  5CXA A;  1XUC A;  3LQB A;  3F16 A;  1K7G A;  4XCT A;  3MA2 A;  4ILW D;  2W0D A;  4GWN A;  3DTK A;  5H8X A;  1BKC E;  2J0T A;  1K7I A;  4GUY A;  3WV2 A;  3F17 A;  1GE7 A;  2D1O A;  4R3V A;  1XUR A;  2O3E A;  1A85 A;  1KUF A;  4I35 A;  3LE9 A;  1CAQ A;  1YCM A;  3HY7 A;  1CK7 A;  4DV8 A;  1MMQ A;  3ZXH A;  4HX3 A;  3KEK A;  4GWM A;  1BUV M;  3KWV C;  4ZR5 A;  3ZUK A;  1XUD A;  3L0V A;  1OO9 A;  1Y0V A;  4PKS A;  1IAE A;  1HFS A;  4FXY P;  5I2Z A;  2JT6 A;  1UEA A;  1Q3A A;  2MZI A;  5D7W A;  1JJ9 A;  1OM8 A;  2WO8 A;  1EUB A;  3KHI A;  1GXD A;  3EHX A;  4H1Q A;  2X3C A;  2OVX A;  4GR8 A;  1A86 A;  1HFC A;  3VTG A;  1D8M A;  2POJ A;  4IUW A;  2XS3 A;  3RTT A;  1CIZ A;  1Y8J A;  2MLS A;  3EWJ A;  1PWU A;  1B8Y A;  1FBL A;  3DPF A;  1DTH A;  2WO9 A;  1G49 A;  3AYU A;  2TCL A;  4L63 A;  1UTT A;  4Q1L A;  2YIG A;  3LIR A;  3F19 A;  1CGL A;  3DTI A;  5D2B A;  2JIH A;  2ERO A;  1PWP A;  1QJJ A;  3USN A;  2I47 A;  3B2Z A;  4A7B A;  1XFW A;  1BKC A;  4H2E A;  3LKA A;  4IJO A;  1PWV A;  3HDB A;  4WZV A;  1CQR A;  3EDH A;  1ZXC A;  1I73 A;  1QUA A;  3KEC A;  3TT4 A;  3I7I A;  1XM5 A;  5D1U A;  1SRP A;  1R1H A;  4QKZ A;  1JIW P;  1OM7 A;  1IAG A;  2AYK A;  3CKI A;  2YB9 A;  2XS4 A;  4PKQ A;  3L0T A;  3LUN A;  4GR0 A;  3WV3 A;  4XM8 A;  1QJI A;  2ERP A;  5BOT A;  2YUF A;  1C7K A;  1G4K A;  1JK3 A;  3LJZ A;  2MZE A;  3HY9 A;  2N8R A;  3O64 A;  4H82 A;  1S4B P;  1WNI A;  1RM8 A;  3LJG A;  1FM1 A;  3HYG A;  3KRY A;  3GBO A;  1HOV A;  5D1S A;  2ERQ A;  4H30 A;  1SMP A;  4WKE A;  3G5C A;  3KMC A;  1EB6 A;  3LK8 A;  1XFV A;  3DNG A;  3SHI A;  4JP4 A; 
#chains in the Genus database with same CATH homology
 3LUM A;  3Q2G A;  1GE5 A;  1I76 A;  2DW2 A;  1ZS0 A;  1AKL A;  1HY7 A;  1R54 A;  2Y6C A;  2JT5 A;  4PKV A;  2USN A;  1ROS A;  5B5P A;  1HTD A;  4DD8 A;  4L7A A;  1FLS A;  2W15 A;  5D1T A;  2K2G A;  4L6T A;  2MLR A;  2RJQ A;  4G0D A;  2E3X A;  5I43 A;  3U1R A;  2A8H A;  3EDI A;  1H71 P;  1OM6 A;  1JAO A;  5CZM A;  1L6J A;  1ND1 A;  1IAC A;  5I3M A;  3RTS A;  4IN9 A;  1BUD A;  1USN A;  5D3C A;  1QIC A;  1OS9 A;  2OW9 A;  1GKD A;  4H76 A;  3G42 A;  4PKR A;  1MMP A;  1R1J A;  2OY4 A;  3TS4 A;  1C3I A;  4ON1 A;  1HV5 A;  3KEJ A;  3LQ0 A;  4XM7 A;  3I7G A;  1I1I P;  2OXU A;  1IAB A;  1UTZ A;  3ZVS A;  1SU3 A;  1MMR A;  2OXW A;  1PWW A;  1IAD A;  2OZR A;  1BKC I;  2KRJ A;  3N2V A;  2OW2 A;  1CGE A;  4JIJ A;  3UVC A;  2AIG P;  2JSD A;  5BOY A;  1KUH A;  2X3A A;  3DL1 A;  1ZXV A;  4XM6 A;  4WKI A;  4H84 A;  2W14 A;  1MMB A;  1C8T A;  1KBC A;  1JAP A;  1CXV A;  5L79 A;  1JKY A;  3WV1 A;  4H3X A;  1G12 A;  4J4M A;  1YOU A;  1GKC A;  1UMS A;  4WF6 A;  3Q2H A;  3K7L A;  3DSL A;  3LIL A;  2DDY A;  4WK7 A;  4GR3 A;  1CGF A;  2MZH A;  4PKT A;  2OVZ A;  3TVC A;  1Y93 A;  1MNC A;  1SLM A;  1G9K A;  3AYK A;  2DW1 A;  4DF9 A;  4L19 A;  2O36 A;  1ZP5 A;  3E8R A;  5B5O A;  1AF0 A;  2D1N A;  1XFZ A;  2RJP A;  2K9C A;  4G9L A;  4DPE A;  2OY2 A;  2OXZ A;  1D5J A;  5BPA A;  3VI1 A;  2J83 A;  1BM6 A;  1JAQ A;  1JH1 A;  1OS2 A;  1KUI A;  2PJT A;  1SAT A;  1XFY A;  2OW1 A;  966C A;  4FU4 A;  2W13 A;  1YP1 A;  1ZTQ A;  1BQQ M;  4HMA A;  1BZS A;  3HB2 P;  1UMT A;  5LAB A;  4JA1 A;  2W12 A;  1RMZ A;  5I0L A;  1SLN A;  2DDF A;  1ZVX A;  1R55 A;  4AIG A;  1B3D A;  4EFS A;  1Z3J A;  5I12 A;  1GO7 P;  3F15 A;  5I4O A;  2OI0 A;  1QIB A;  1BQO A;  1BIW A;  3DWB A;  2X3B A;  1EAK A;  3O2X A;  2FV9 A;  3N2U A;  3F18 A;  3BA0 A;  4FVL A;  1JIZ A;  830C A;  4PKU A;  3LMC A;  3EDZ A;  1JAN A;  2L0R A;  456C A;  2X7M A;  1D7X A;  3NX7 A;  3OHO A;  2FV5 A;  4PKW A;  1GE6 A;  3ELM A;  2WOA A;  4AUO A;  3V96 B;  1YQY A;  1PWQ A;  4H49 A;  5CUH A;  3LGP A;  4I03 A;  4JPA A;  4GF1 A;  3F1A A;  2HU6 A;  1KAP P;  1GO8 P;  2Y6D A;  1XFU A;  2V4B A;  1ATL A;  1BSW A;  1XFX A;  2E2D A;  5L7F A;  1O0Q A;  3P24 A;  1DMT A;  1J7N A;  1OMJ A;  2QPJ A;  2CLT A;  1O0T A;  3P1V A;  1AST A;  3B8Z A;  3EDG A;  4AYK A;  1KUG A;  4AXQ A;  3EHY A;  2CKI A;  3B92 A;  1KUK A;  5JMY A;  1R1I A;  3HBV P;  3DTE A;  4GQL A;  1K7Q A;  2OW0 A;  3LIK A;  1IAA A;  3OHL A;  3K7N A;  3HDA P;  3AIG A;  4JQG A;  4FXQ A;  3LEA A;  3HBU P;  2DW0 A;  1G05 A;  3TSK A;  3KME A;  1QIA A;  3DPE A;  1AYK A;  2Z2D A;  4A3W A;  2JNP A;  3LJT A;  4CTH A;  4XBH A;  2SRT A;  1D8F A;  5CXA A;  1XUC A;  3LQB A;  3F16 A;  1K7G A;  4XCT A;  3MA2 A;  4ILW D;  2W0D A;  4GWN A;  3DTK A;  5H8X A;  1BKC E;  2J0T A;  1K7I A;  4GUY A;  3WV2 A;  3F17 A;  1GE7 A;  2D1O A;  4R3V A;  1XUR A;  2O3E A;  1A85 A;  1KUF A;  4I35 A;  3LE9 A;  1CAQ A;  1YCM A;  3HY7 A;  1CK7 A;  4DV8 A;  1MMQ A;  3ZXH A;  4HX3 A;  3KEK A;  4GWM A;  1BUV M;  3KWV C;  4ZR5 A;  3ZUK A;  1XUD A;  3L0V A;  1OO9 A;  1Y0V A;  4PKS A;  1IAE A;  1HFS A;  4FXY P;  5I2Z A;  2JT6 A;  1UEA A;  1Q3A A;  2MZI A;  5D7W A;  1JJ9 A;  1OM8 A;  2WO8 A;  1EUB A;  3KHI A;  1GXD A;  3EHX A;  4H1Q A;  2X3C A;  2OVX A;  4GR8 A;  1A86 A;  1HFC A;  3VTG A;  1D8M A;  2POJ A;  4IUW A;  2XS3 A;  3RTT A;  1CIZ A;  1Y8J A;  2MLS A;  3EWJ A;  1PWU A;  1B8Y A;  1FBL A;  3DPF A;  1DTH A;  2WO9 A;  1G49 A;  3AYU A;  2TCL A;  4L63 A;  1UTT A;  4Q1L A;  2YIG A;  3LIR A;  3F19 A;  1CGL A;  3DTI A;  5D2B A;  2JIH A;  2ERO A;  1PWP A;  1QJJ A;  3USN A;  2I47 A;  3B2Z A;  4A7B A;  1XFW A;  1BKC A;  4H2E A;  3LKA A;  4IJO A;  1PWV A;  3HDB A;  4WZV A;  1CQR A;  3EDH A;  1ZXC A;  1I73 A;  1QUA A;  3KEC A;  3TT4 A;  3I7I A;  5D1U A;  1SRP A;  1R1H A;  4QKZ A;  1JIW P;  1OM7 A;  1IAG A;  2AYK A;  3CKI A;  2YB9 A;  2XS4 A;  4PKQ A;  3L0T A;  3LUN A;  4GR0 A;  3WV3 A;  4XM8 A;  1QJI A;  2ERP A;  5BOT A;  2YUF A;  1C7K A;  1G4K A;  1JK3 A;  3LJZ A;  2MZE A;  3HY9 A;  2N8R A;  3O64 A;  4H82 A;  1S4B P;  1WNI A;  1RM8 A;  3LJG A;  1FM1 A;  3HYG A;  3KRY A;  3GBO A;  1HOV A;  5D1S A;  2ERQ A;  4H30 A;  1SMP A;  4WKE A;  3G5C A;  3KMC A;  1EB6 A;  3LK8 A;  1XFV A;  3DNG A;  3SHI A;  4JP4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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