4H96A

Candida albicans dihydrofolate reductase complexed with nadph and 5-{3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyphenyl]prop-1-yn-1-yl}-6-ethylpyrimidine-2,4-diamine (ucp1018)
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
189
structure length
189
Chain Sequence
PNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
pubmed doi rcsb
molecule keywords Dihydrofolate Reductase
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Candida albicans
total genus 46
structure length 189
sequence length 189
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4h96A00
3JWMA 2C2TA 1RE7A 3EEJA 2W3BA 5EAJA 4LAEX 2JYBA 3IA5A 4LAGX 5U27A 3F0UX 1DDRA 3GI2A 3FY9X 1DYJA 1DR6A 3IRMA 4LEKX 1BOZA 2FZIA 6DFRA 1DG7A 3OAFA 1RX8A 1OHKA 1RX7A 4QI9A 4M6JA 1SEJA 1AOEA 2LF1A 1DREA 1LY4A 3NZBX 1RB2A 3JWKA 3FYWX 1CZ3A 2HXVA 1YHOA 3EEKA 4XECX 4M6LA 2W3AA 5DFRA 3Q1HA 4KJLA 4EILA 1KMVA 2BLBA 5HQZA 1RX1A 1DG8A 3L3RA 3FQOA 4X5FA 1IA3A 4FGHA 2H2QA 1RA8A 4ELFA 4XT4A 1VDRA 3QLZA 4KD7A 2HQPA 3FQVA 1ZDRA 3FRFX 4QHVA 1DR7A 4Q6AA 3SAIA 3JW5A 1RB3A 4QLGA 1CD2A 3R33A 4KLXA 5CCCA 1RD7A 3SGYA 4X5HA 1D1GA 3DG8A 1RX2A 4X5JA 5JG0X 2QK8A 3DAUA 2KGKA 1HFPA 4XT8A 3JWCA 4DFRA 1DHFA 5HVEA 4TU5X 1J3JA 1PDBA 3HJ3A 3NXYA 4HOEA 3E0BA 4DPHA 1M79A 3NXOA 3IRNA 3RO9A 1JOLA 1LUDA 1DR2A 4KNEA 3QYOA 3CL9A 3NTZA 3QYLA 2DHFA 3QL0A 1DLSA 3GHCA 3EX8A 4KFJA 3DL5A 3F0BX 2D5NA 4PDJA 5ECCA 3IX9A 1E26A 3S7AA 3OCHA 4DP3A 2W3WA 1IA1A 1RA2A 2P4GA 3INVA 3FQCA 3CLBA 1OHJA 1DLRA 1TDRA 3NZCX 1DR3A 4KJKA 3ROAA 1IA4A 1S3WA 4M2XA 2W9HA 4NX6A 4HA7A 1DRFA 3JW3A 4P66A 3K74A 4I1NA 1DRHA 3F0SX 3S3VA 3JTWA 4H96A 1DR5A 3NXXA 3SA1A 3F91A 1RA3A 4Q0EA 3DRCA 1PD8A 4RGCA 3TQ8A 4M7VA 4IXGX 1U71A 2W9TA 4XE6X 4PTJA 1RH3A 1DR1A 1JUVA 3JWFA 3ZPGA 3FRBX 4Q0DA 1DG5A 1DRBA 4M7UA 1DHIA 5HSRA 1JOMA 3NXRA 1RX9A 3QLWA 2INQA 4QLFA 4H97A 2HM9A 4I13A 4QLEA 2G6VA 3NZ9X 3KJRA 4EIGA 3QLRA 4P68A 1J3IA 4DDRA 3CD2A 3FRAX 3FREX 1S3VA 4IXFX 1RX5A 3EEMA 1AO8A 4KAKA 4FGGA 5HVBA 3F0VX 5HF2X 1DRAA 1IA2A 3F0QX 3DFRA 3VCOA 1RA9A 1RA1A 3QLXA 4HOGA 4EIZA 4XT5A 3NXVA 4PTHA 3SRSX 4CD2A 5HUIA 5HF0X 3KGYA 3FYVX 3F0XX 4P3RA 3CSEA 2FZJA 3TQ9A 3ZPCA 3N0HA 1DHJA 1DISA 3D84X 4DPDA 1KLKA 1M7AA 3SRQX 3SR5X 3QFXA 5JA3A 3NZ6X 4NX7A 1RC4A 3IA4A 1MVSA 4XT7A 3M09A 2XW7A 4IXED 5HT5A 3FL8A 3LG4A 3QLSA 3D80A 3GHWA 3NXTA 7DFRA 1J3KA 3QL3A 5ECXA 2D0KA 3SQYX 5DXVA 3UM6A 4GH8A 4KL9A 4ECKA 2BLAA 4ELHA 3FQ0A 5U26A 5CC9A 3DGAA 1S3UA 4OR7A 3NZAX 3NU0A 4PSTA 5HQYA 1HFRA 3FS6A 3QG2A 1DAJA 4ELGA 3DL6A 3GYFA 4KJJA 3UM8A 4XRBA 5HPBA 1U70A 4PSYA 3M08A 1RX6A 1RX4A 3QLYA 3IROA 3QGTA 2BL9A 4HOFA 3NZDA 2ANOA 3K2HA 3F8YA 1S3YA 3TD8A 1RX3A 2ZZAA 1DF7A 1PD9A 2W3VA 4ELBA 1DIUA 2ANQA 3HBBA 2ITHA 2BLCA 4XT6A 3FL9A 5E8QA 4KY4A 4QJZD 3KFYA 1VJ3A 1DDSA 4LAHX 3I3RA 3FY8X 3SH2A 3GHVA 2GD9A 1DR4A 4Q67A 3SRRX 3S9UA 3NRRA 4KEBA 3EELA 2C2SA 4KM2A 5FDAA 3RG9A 1HFQA 3TQBA 8DFRA 3KJSA 4P3QA 2L28A 2OIPA 1MVTA 1RF7A 1DYIA 3K45A 1DYHA 3FQZA 1M78A 3SRWX 1RG7A 3JSUA 4OSGA 2B3ZA 3I8AX 3K47A 2OBCA 1DYRA 4G8ZX 4G95A 4H95A 4QJCA 4H98A 2O7PA 3SRUX 1BZFA 2W9SA 4KYAA 2W3MA 1KMSA 4X5IA 3UM5A 2W9GA 3FQFA 5HI6A 1LY3A 3DATA 4PSSA 4HA9A 4EJ1A 5HT4A 2CD2A 4KBNA 4X5GA 1AI9A 3JVXA 2AZNA 3FRDX 3SA2A 5HSUA 4ELEA 4FHBA 4KM0A 3TQAA 3KY8A 1QZFA 2DRCA 3EIGA 4KY8A 2CIGA 1U72A 2FZHA 3F8ZA 4G3MA 4M6KA
chains in the Genus database with same CATH superfamily
3JWMA 2C2TA 1RE7A 3EEJA 2W3BA 5EAJA 4LAEX 2JYBA 3IA5A 4LAGX 5U27A 3F0UX 1DDRA 3GI2A 3FY9X 1DYJA 1DR6A 3IRMA 4LEKX 1BOZA 2FZIA 6DFRA 1DG7A 3OAFA 1RX8A 1OHKA 1RX7A 4QI9A 4M6JA 1SEJA 1AOEA 2LF1A 1DREA 1LY4A 3NZBX 1RB2A 3JWKA 3FYWX 1CZ3A 2HXVA 1YHOA 3EEKA 4XECX 4M6LA 2W3AA 5DFRA 3Q1HA 4KJLA 4EILA 1KMVA 2BLBA 5HQZA 1RX1A 1DG8A 3L3RA 3FQOA 4X5FA 1IA3A 4FGHA 2H2QA 1RA8A 4ELFA 4XT4A 1VDRA 3QLZA 4KD7A 2HQPA 3FQVA 1ZDRA 3FRFX 4QHVA 1DR7A 4Q6AA 3SAIA 3JW5A 1RB3A 4QLGA 1CD2A 3R33A 4KLXA 5CCCA 1RD7A 3SGYA 4X5HA 1D1GA 3DG8A 1RX2A 4X5JA 5JG0X 2QK8A 3DAUA 2KGKA 1HFPA 4XT8A 3JWCA 4DFRA 1DHFA 5HVEA 4TU5X 1J3JA 1PDBA 3HJ3A 3NXYA 4HOEA 3E0BA 4DPHA 1M79A 3NXOA 3IRNA 3RO9A 1JOLA 1LUDA 1DR2A 4KNEA 3QYOA 3CL9A 3NTZA 3QYLA 2DHFA 3QL0A 1DLSA 3GHCA 3EX8A 4KFJA 3DL5A 3F0BX 2D5NA 4PDJA 5ECCA 3IX9A 1E26A 3S7AA 3OCHA 4DP3A 2W3WA 1IA1A 1RA2A 2P4GA 3INVA 3FQCA 3CLBA 1OHJA 1DLRA 1TDRA 3NZCX 1DR3A 4KJKA 3ROAA 1IA4A 1S3WA 4M2XA 2W9HA 4NX6A 4HA7A 1DRFA 3JW3A 4P66A 3K74A 4I1NA 1DRHA 3F0SX 3S3VA 3JTWA 4H96A 1DR5A 3NXXA 3SA1A 3F91A 1RA3A 4Q0EA 3DRCA 1PD8A 4RGCA 3TQ8A 4M7VA 4IXGX 1U71A 2W9TA 4XE6X 4PTJA 1RH3A 1DR1A 1JUVA 3JWFA 3ZPGA 3FRBX 4Q0DA 1DG5A 1DRBA 4M7UA 1DHIA 5HSRA 1JOMA 3NXRA 1RX9A 3QLWA 2INQA 4QLFA 4H97A 2HM9A 4I13A 4QLEA 2G6VA 3NZ9X 3KJRA 4EIGA 3QLRA 4P68A 1J3IA 4DDRA 3CD2A 3FRAX 3FREX 1S3VA 4IXFX 1RX5A 3EEMA 1AO8A 4KAKA 4FGGA 5HVBA 3F0VX 5HF2X 1DRAA 1IA2A 3F0QX 3DFRA 3VCOA 1RA9A 1RA1A 3QLXA 4HOGA 4EIZA 4XT5A 3NXVA 4PTHA 3SRSX 4CD2A 5HUIA 5HF0X 3KGYA 3FYVX 3F0XX 4P3RA 3CSEA 2FZJA 3TQ9A 3ZPCA 3N0HA 1DHJA 1DISA 3D84X 4DPDA 1KLKA 1M7AA 3SRQX 3SR5X 3QFXA 5JA3A 3NZ6X 4NX7A 1RC4A 3IA4A 1MVSA 4XT7A 3M09A 2XW7A 4IXED 5HT5A 3FL8A 3LG4A 3QLSA 3D80A 3GHWA 3NXTA 7DFRA 1J3KA 3QL3A 5ECXA 2D0KA 3SQYX 5DXVA 3UM6A 4GH8A 4KL9A 4ECKA 2BLAA 4ELHA 3FQ0A 5U26A 5CC9A 3DGAA 1S3UA 4OR7A 3NZAX 3NU0A 4PSTA 5HQYA 1HFRA 3FS6A 3QG2A 1DAJA 4ELGA 3DL6A 3GYFA 4KJJA 3UM8A 4XRBA 5HPBA 1U70A 4PSYA 3M08A 1RX6A 1RX4A 3QLYA 3IROA 3QGTA 2BL9A 4HOFA 3NZDA 2ANOA 3K2HA 3F8YA 1S3YA 3TD8A 1RX3A 2ZZAA 1DF7A 1PD9A 2W3VA 4ELBA 1DIUA 2ANQA 3HBBA 2ITHA 2BLCA 4XT6A 3FL9A 5E8QA 4KY4A 4QJZD 3KFYA 1VJ3A 1DDSA 4LAHX 3I3RA 3FY8X 3SH2A 3GHVA 2GD9A 1DR4A 4Q67A 3SRRX 3S9UA 3NRRA 4KEBA 3EELA 2C2SA 4KM2A 5FDAA 3RG9A 1HFQA 3TQBA 8DFRA 3KJSA 4P3QA 2L28A 2OIPA 1MVTA 1RF7A 1DYIA 3K45A 1DYHA 3FQZA 1M78A 3SRWX 1RG7A 3JSUA 4OSGA 2B3ZA 3I8AX 3K47A 2OBCA 1DYRA 4G8ZX 4G95A 4H95A 4QJCA 4H98A 2O7PA 3SRUX 1BZFA 2W9SA 4KYAA 2W3MA 1KMSA 4X5IA 3UM5A 2W9GA 3FQFA 5HI6A 1LY3A 3DATA 4PSSA 4HA9A 4EJ1A 5HT4A 2CD2A 4KBNA 4X5GA 1AI9A 3JVXA 2AZNA 3FRDX 3SA2A 5HSUA 4ELEA 4FHBA 4KM0A 3TQAA 3KY8A 1QZFA 2DRCA 3EIGA 4KY8A 2CIGA 1U72A 2FZHA 3F8ZA 4G3MA 4M6KA
chains in the Genus database with same CATH topology
3JWMA 2C2TA 1RE7A 3EEJA 2W3BA 5EAJA 4LAEX 2JYBA 3IA5A 4LAGX 5U27A 3F0UX 1DDRA 3GI2A 3FY9X 1DYJA 1DR6A 3IRMA 4LEKX 1BOZA 2FZIA 6DFRA 1DG7A 3OAFA 1RX8A 1OHKA 1RX7A 4QI9A 4M6JA 1SEJA 1AOEA 2LF1A 1DREA 1LY4A 3NZBX 1RB2A 3JWKA 3FYWX 1CZ3A 2HXVA 1YHOA 3EEKA 4XECX 4M6LA 2W3AA 5DFRA 3Q1HA 4KJLA 4EILA 1KMVA 2BLBA 5HQZA 1RX1A 1DG8A 3L3RA 3FQOA 4X5FA 1IA3A 4FGHA 2H2QA 1RA8A 4ELFA 4XT4A 1VDRA 3QLZA 4KD7A 2HQPA 3FQVA 1ZDRA 3FRFX 4QHVA 1DR7A 4Q6AA 3SAIA 3JW5A 1RB3A 4QLGA 1CD2A 3R33A 4KLXA 5CCCA 1RD7A 3SGYA 4X5HA 1D1GA 3DG8A 1RX2A 4X5JA 5JG0X 2QK8A 3DAUA 2KGKA 1HFPA 4XT8A 3JWCA 4DFRA 1DHFA 5HVEA 4TU5X 1J3JA 1PDBA 3HJ3A 3NXYA 4HOEA 3E0BA 4DPHA 1M79A 3NXOA 3IRNA 3RO9A 1JOLA 1LUDA 1DR2A 4KNEA 3QYOA 3CL9A 3NTZA 3QYLA 2DHFA 3QL0A 1DLSA 3GHCA 3EX8A 4KFJA 3DL5A 3F0BX 2D5NA 4PDJA 5ECCA 3IX9A 1E26A 3S7AA 3OCHA 4DP3A 2W3WA 1IA1A 1RA2A 2P4GA 3INVA 3FQCA 3CLBA 1OHJA 1DLRA 1TDRA 3NZCX 1DR3A 4KJKA 3ROAA 1IA4A 1S3WA 4M2XA 2W9HA 4NX6A 4HA7A 1DRFA 3JW3A 4P66A 3K74A 4I1NA 1DRHA 3F0SX 3S3VA 3JTWA 4H96A 1DR5A 3NXXA 3SA1A 3F91A 1RA3A 4Q0EA 3DRCA 1PD8A 4RGCA 3TQ8A 4M7VA 4IXGX 1U71A 2W9TA 4XE6X 4PTJA 1RH3A 1DR1A 1JUVA 3JWFA 3ZPGA 3FRBX 4Q0DA 1DG5A 1DRBA 4M7UA 1DHIA 5HSRA 1JOMA 3NXRA 1RX9A 3QLWA 2INQA 4QLFA 4H97A 2HM9A 4I13A 4QLEA 2G6VA 3NZ9X 3KJRA 4EIGA 3QLRA 4P68A 1J3IA 4DDRA 3CD2A 3FRAX 3FREX 1S3VA 4IXFX 1RX5A 3EEMA 1AO8A 4KAKA 4FGGA 5HVBA 3F0VX 5HF2X 1DRAA 1IA2A 3F0QX 3DFRA 3VCOA 1RA9A 1RA1A 3QLXA 4HOGA 4EIZA 4XT5A 3NXVA 4PTHA 3SRSX 4CD2A 5HUIA 5HF0X 3KGYA 3FYVX 3F0XX 4P3RA 3CSEA 2FZJA 3TQ9A 3ZPCA 3N0HA 1DHJA 1DISA 3D84X 4DPDA 1KLKA 1M7AA 3SRQX 3SR5X 3QFXA 5JA3A 3NZ6X 4NX7A 1RC4A 3IA4A 1MVSA 4XT7A 3M09A 2XW7A 4IXED 5HT5A 3FL8A 3LG4A 3QLSA 3D80A 3GHWA 3NXTA 7DFRA 1J3KA 3QL3A 5ECXA 2D0KA 3SQYX 5DXVA 3UM6A 4GH8A 4KL9A 4ECKA 2BLAA 4ELHA 3FQ0A 5U26A 5CC9A 3DGAA 1S3UA 4OR7A 3NZAX 3NU0A 4PSTA 5HQYA 1HFRA 3FS6A 3QG2A 1DAJA 4ELGA 3DL6A 3GYFA 4KJJA 3UM8A 4XRBA 5HPBA 1U70A 4PSYA 3M08A 1RX6A 1RX4A 3QLYA 3IROA 3QGTA 2BL9A 4HOFA 3NZDA 2ANOA 3K2HA 3F8YA 1S3YA 3TD8A 1RX3A 2ZZAA 1DF7A 1PD9A 2W3VA 4ELBA 1DIUA 2ANQA 3HBBA 2ITHA 2BLCA 4XT6A 3FL9A 5E8QA 4KY4A 4QJZD 3KFYA 1VJ3A 1DDSA 4LAHX 3I3RA 3FY8X 3SH2A 3GHVA 2GD9A 1DR4A 4Q67A 3SRRX 3S9UA 3NRRA 4KEBA 3EELA 2C2SA 4KM2A 5FDAA 3RG9A 1HFQA 3TQBA 8DFRA 3KJSA 4P3QA 2L28A 2OIPA 1MVTA 1RF7A 1DYIA 3K45A 1DYHA 3FQZA 1M78A 3SRWX 1RG7A 3JSUA 4OSGA 2B3ZA 3I8AX 3K47A 2OBCA 1DYRA 4G8ZX 4G95A 4H95A 4QJCA 4H98A 2O7PA 3SRUX 1BZFA 2W9SA 4KYAA 2W3MA 1KMSA 4X5IA 3UM5A 2W9GA 3FQFA 5HI6A 1LY3A 3DATA 4PSSA 4HA9A 4EJ1A 5HT4A 2CD2A 4KBNA 4X5GA 1AI9A 3JVXA 2AZNA 3FRDX 3SA2A 5HSUA 4ELEA 4FHBA 4KM0A 3TQAA 3KY8A 1QZFA 2DRCA 3EIGA 4KY8A 2CIGA 1U72A 2FZHA 3F8ZA 4G3MA 4M6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JWM A;  2C2T A;  1RE7 A;  3EEJ A;  2W3B A;  5EAJ A;  4LAE X;  2JYB A;  3IA5 A;  4LAG X;  5U27 A;  3F0U X;  1DDR A;  3GI2 A;  3FY9 X;  1DYJ A;  1DR6 A;  3IRM A;  4LEK X;  1BOZ A;  2FZI A;  6DFR A;  1DG7 A;  3OAF A;  1RX8 A;  1OHK A;  1RX7 A;  4QI9 A;  4M6J A;  1SEJ A;  1AOE A;  2LF1 A;  1DRE A;  1LY4 A;  3NZB X;  1RB2 A;  3JWK A;  3FYW X;  1CZ3 A;  2HXV A;  1YHO A;  3EEK A;  4XEC X;  4M6L A;  2W3A A;  5DFR A;  3Q1H A;  4KJL A;  4EIL A;  1KMV A;  2BLB A;  5HQZ A;  1RX1 A;  1DG8 A;  3L3R A;  3FQO A;  4X5F A;  1IA3 A;  4FGH A;  2H2Q A;  1RA8 A;  4ELF A;  4XT4 A;  1VDR A;  3QLZ A;  4KD7 A;  2HQP A;  3FQV A;  1ZDR A;  3FRF X;  4QHV A;  1DR7 A;  4Q6A A;  3SAI A;  3JW5 A;  1RB3 A;  4QLG A;  1CD2 A;  3R33 A;  4KLX A;  5CCC A;  1RD7 A;  3SGY A;  4X5H A;  1D1G A;  3DG8 A;  1RX2 A;  4X5J A;  5JG0 X;  2QK8 A;  3DAU A;  2KGK A;  1HFP A;  4XT8 A;  3JWC A;  4DFR A;  1DHF A;  5HVE A;  4TU5 X;  1J3J A;  1PDB A;  3HJ3 A;  3NXY A;  4HOE A;  3E0B A;  4DPH A;  1M79 A;  3NXO A;  3IRN A;  3RO9 A;  1JOL A;  1LUD A;  1DR2 A;  4KNE A;  3QYO A;  3CL9 A;  3NTZ A;  3QYL A;  2DHF A;  3QL0 A;  1DLS A;  3GHC A;  3EX8 A;  4KFJ A;  3DL5 A;  3F0B X;  2D5N A;  4PDJ A;  5ECC A;  3IX9 A;  1E26 A;  3S7A A;  3OCH A;  4DP3 A;  2W3W A;  1IA1 A;  1RA2 A;  2P4G A;  3INV A;  3FQC A;  3CLB A;  1OHJ A;  1DLR A;  1TDR A;  3NZC X;  1DR3 A;  4KJK A;  3ROA A;  1IA4 A;  1S3W A;  4M2X A;  2W9H A;  4NX6 A;  4HA7 A;  1DRF A;  3JW3 A;  4P66 A;  3K74 A;  4I1N A;  1DRH A;  3F0S X;  3S3V A;  3JTW A;  4H96 A;  1DR5 A;  3NXX A;  3SA1 A;  3F91 A;  1RA3 A;  4Q0E A;  3DRC A;  1PD8 A;  4RGC A;  3TQ8 A;  4M7V A;  4IXG X;  1U71 A;  2W9T A;  4XE6 X;  4PTJ A;  1RH3 A;  1DR1 A;  1JUV A;  3JWF A;  3ZPG A;  3FRB X;  4Q0D A;  1DG5 A;  1DRB A;  4M7U A;  1DHI A;  5HSR A;  1JOM A;  3NXR A;  1RX9 A;  3QLW A;  2INQ A;  4QLF A;  4H97 A;  2HM9 A;  4I13 A;  4QLE A;  2G6V A;  3NZ9 X;  3KJR A;  4EIG A;  3QLR A;  4P68 A;  1J3I A;  4DDR A;  3CD2 A;  3FRA X;  3FRE X;  1S3V A;  4IXF X;  1RX5 A;  3EEM A;  1AO8 A;  4KAK A;  4FGG A;  5HVB A;  3F0V X;  5HF2 X;  1DRA A;  1IA2 A;  3F0Q X;  3DFR A;  3VCO A;  1RA9 A;  1RA1 A;  3QLX A;  4HOG A;  4EIZ A;  4XT5 A;  3NXV A;  4PTH A;  3SRS X;  4CD2 A;  5HUI A;  5HF0 X;  3KGY A;  3FYV X;  3F0X X;  4P3R A;  3CSE A;  2FZJ A;  3TQ9 A;  3ZPC A;  3N0H A;  1DHJ A;  1DIS A;  3D84 X;  4DPD A;  1KLK A;  1M7A A;  3SRQ X;  3SR5 X;  3QFX A;  5JA3 A;  3NZ6 X;  4NX7 A;  1RC4 A;  3IA4 A;  1MVS A;  4XT7 A;  3M09 A;  2XW7 A;  4IXE D;  5HT5 A;  3FL8 A;  3LG4 A;  3QLS A;  3D80 A;  3GHW A;  3NXT A;  7DFR A;  1J3K A;  3QL3 A;  5ECX A;  2D0K A;  3SQY X;  5DXV A;  3UM6 A;  4GH8 A;  4KL9 A;  4ECK A;  2BLA A;  4ELH A;  3FQ0 A;  5U26 A;  5CC9 A;  3DGA A;  1S3U A;  4OR7 A;  3NZA X;  3NU0 A;  4PST A;  5HQY A;  1HFR A;  3FS6 A;  3QG2 A;  1DAJ A;  4ELG A;  3DL6 A;  3GYF A;  4KJJ A;  3UM8 A;  4XRB A;  5HPB A;  1U70 A;  4PSY A;  3M08 A;  1RX6 A;  1RX4 A;  3QLY A;  3IRO A;  3QGT A;  2BL9 A;  4HOF A;  3NZD A;  2ANO A;  3K2H A;  3F8Y A;  1S3Y A;  3TD8 A;  1RX3 A;  2ZZA A;  1DF7 A;  1PD9 A;  2W3V A;  4ELB A;  1DIU A;  2ANQ A;  3HBB A;  2ITH A;  2BLC A;  4XT6 A;  3FL9 A;  5E8Q A;  4KY4 A;  4QJZ D;  3KFY A;  1VJ3 A;  1DDS A;  4LAH X;  3I3R A;  3FY8 X;  3SH2 A;  3GHV A;  2GD9 A;  1DR4 A;  4Q67 A;  3SRR X;  3S9U A;  3NRR A;  4KEB A;  3EEL A;  2C2S A;  4KM2 A;  5FDA A;  3RG9 A;  1HFQ A;  3TQB A;  8DFR A;  3KJS A;  4P3Q A;  2L28 A;  2OIP A;  1MVT A;  1RF7 A;  1DYI A;  3K45 A;  1DYH A;  3FQZ A;  1M78 A;  3SRW X;  1RG7 A;  3JSU A;  4OSG A;  2B3Z A;  3I8A X;  3K47 A;  2OBC A;  1DYR A;  4G8Z X;  4G95 A;  4H95 A;  4QJC A;  4H98 A;  2O7P A;  3SRU X;  1BZF A;  2W9S A;  4KYA A;  2W3M A;  1KMS A;  4X5I A;  3UM5 A;  2W9G A;  3FQF A;  5HI6 A;  1LY3 A;  3DAT A;  4PSS A;  4HA9 A;  4EJ1 A;  5HT4 A;  2CD2 A;  4KBN A;  4X5G A;  1AI9 A;  3JVX A;  2AZN A;  3FRD X;  3SA2 A;  5HSU A;  4ELE A;  4FHB A;  4KM0 A;  3TQA A;  3KY8 A;  1QZF A;  2DRC A;  3EIG A;  4KY8 A;  2CIG A;  1U72 A;  2FZH A;  3F8Z A;  4G3M A;  4M6K A; 
#chains in the Genus database with same CATH topology
 3JWM A;  2C2T A;  1RE7 A;  3EEJ A;  2W3B A;  5EAJ A;  4LAE X;  2JYB A;  3IA5 A;  4LAG X;  5U27 A;  3F0U X;  1DDR A;  3GI2 A;  3FY9 X;  1DYJ A;  1DR6 A;  3IRM A;  4LEK X;  1BOZ A;  2FZI A;  6DFR A;  1DG7 A;  3OAF A;  1RX8 A;  1OHK A;  1RX7 A;  4QI9 A;  4M6J A;  1SEJ A;  1AOE A;  2LF1 A;  1DRE A;  1LY4 A;  3NZB X;  1RB2 A;  3JWK A;  3FYW X;  1CZ3 A;  2HXV A;  1YHO A;  3EEK A;  4XEC X;  4M6L A;  2W3A A;  5DFR A;  3Q1H A;  4KJL A;  4EIL A;  1KMV A;  2BLB A;  5HQZ A;  1RX1 A;  1DG8 A;  3L3R A;  3FQO A;  4X5F A;  1IA3 A;  4FGH A;  2H2Q A;  1RA8 A;  4ELF A;  4XT4 A;  1VDR A;  3QLZ A;  4KD7 A;  2HQP A;  3FQV A;  1ZDR A;  3FRF X;  4QHV A;  1DR7 A;  4Q6A A;  3SAI A;  3JW5 A;  1RB3 A;  4QLG A;  1CD2 A;  3R33 A;  4KLX A;  5CCC A;  1RD7 A;  3SGY A;  4X5H A;  1D1G A;  3DG8 A;  1RX2 A;  4X5J A;  5JG0 X;  2QK8 A;  3DAU A;  2KGK A;  1HFP A;  4XT8 A;  3JWC A;  4DFR A;  1DHF A;  5HVE A;  4TU5 X;  1J3J A;  1PDB A;  3HJ3 A;  3NXY A;  4HOE A;  3E0B A;  4DPH A;  1M79 A;  3NXO A;  3IRN A;  3RO9 A;  1JOL A;  1LUD A;  1DR2 A;  4KNE A;  3QYO A;  3CL9 A;  3NTZ A;  3QYL A;  2DHF A;  3QL0 A;  1DLS A;  3GHC A;  3EX8 A;  4KFJ A;  3DL5 A;  3F0B X;  2D5N A;  4PDJ A;  5ECC A;  3IX9 A;  1E26 A;  3S7A A;  3OCH A;  4DP3 A;  2W3W A;  1IA1 A;  1RA2 A;  2P4G A;  3INV A;  3FQC A;  3CLB A;  1OHJ A;  1DLR A;  1TDR A;  3NZC X;  1DR3 A;  4KJK A;  3ROA A;  1IA4 A;  1S3W A;  4M2X A;  2W9H A;  4NX6 A;  4HA7 A;  1DRF A;  3JW3 A;  4P66 A;  3K74 A;  4I1N A;  1DRH A;  3F0S X;  3S3V A;  3JTW A;  4H96 A;  1DR5 A;  3NXX A;  3SA1 A;  3F91 A;  1RA3 A;  4Q0E A;  3DRC A;  1PD8 A;  4RGC A;  3TQ8 A;  4M7V A;  4IXG X;  1U71 A;  2W9T A;  4XE6 X;  4PTJ A;  1RH3 A;  1DR1 A;  1JUV A;  3JWF A;  3ZPG A;  3FRB X;  4Q0D A;  1DG5 A;  1DRB A;  4M7U A;  1DHI A;  5HSR A;  1JOM A;  3NXR A;  1RX9 A;  3QLW A;  2INQ A;  4QLF A;  4H97 A;  2HM9 A;  4I13 A;  4QLE A;  2G6V A;  3NZ9 X;  3KJR A;  4EIG A;  3QLR A;  4P68 A;  1J3I A;  4DDR A;  3CD2 A;  3FRA X;  3FRE X;  1S3V A;  4IXF X;  1RX5 A;  3EEM A;  1AO8 A;  4KAK A;  4FGG A;  5HVB A;  3F0V X;  5HF2 X;  1DRA A;  1IA2 A;  3F0Q X;  3DFR A;  3VCO A;  1RA9 A;  1RA1 A;  3QLX A;  4HOG A;  4EIZ A;  4XT5 A;  3NXV A;  4PTH A;  3SRS X;  4CD2 A;  5HUI A;  5HF0 X;  3KGY A;  3FYV X;  3F0X X;  4P3R A;  3CSE A;  2FZJ A;  3TQ9 A;  3ZPC A;  3N0H A;  1DHJ A;  1DIS A;  3D84 X;  4DPD A;  1KLK A;  1M7A A;  3SRQ X;  3SR5 X;  3QFX A;  5JA3 A;  3NZ6 X;  4NX7 A;  1RC4 A;  3IA4 A;  1MVS A;  4XT7 A;  3M09 A;  2XW7 A;  4IXE D;  5HT5 A;  3FL8 A;  3LG4 A;  3QLS A;  3D80 A;  3GHW A;  3NXT A;  7DFR A;  1J3K A;  3QL3 A;  5ECX A;  2D0K A;  3SQY X;  5DXV A;  3UM6 A;  4GH8 A;  4KL9 A;  4ECK A;  2BLA A;  4ELH A;  3FQ0 A;  5U26 A;  5CC9 A;  3DGA A;  1S3U A;  4OR7 A;  3NZA X;  3NU0 A;  4PST A;  5HQY A;  1HFR A;  3FS6 A;  3QG2 A;  1DAJ A;  4ELG A;  3DL6 A;  3GYF A;  4KJJ A;  3UM8 A;  4XRB A;  5HPB A;  1U70 A;  4PSY A;  3M08 A;  1RX6 A;  1RX4 A;  3QLY A;  3IRO A;  3QGT A;  2BL9 A;  4HOF A;  3NZD A;  2ANO A;  3K2H A;  3F8Y A;  1S3Y A;  3TD8 A;  1RX3 A;  2ZZA A;  1DF7 A;  1PD9 A;  2W3V A;  4ELB A;  1DIU A;  2ANQ A;  3HBB A;  2ITH A;  2BLC A;  4XT6 A;  3FL9 A;  5E8Q A;  4KY4 A;  4QJZ D;  3KFY A;  1VJ3 A;  1DDS A;  4LAH X;  3I3R A;  3FY8 X;  3SH2 A;  3GHV A;  2GD9 A;  1DR4 A;  4Q67 A;  3SRR X;  3S9U A;  3NRR A;  4KEB A;  3EEL A;  2C2S A;  4KM2 A;  5FDA A;  3RG9 A;  1HFQ A;  3TQB A;  8DFR A;  3KJS A;  4P3Q A;  2L28 A;  2OIP A;  1MVT A;  1RF7 A;  1DYI A;  3K45 A;  1DYH A;  3FQZ A;  1M78 A;  3SRW X;  1RG7 A;  3JSU A;  4OSG A;  2B3Z A;  3I8A X;  3K47 A;  2OBC A;  1DYR A;  4G8Z X;  4G95 A;  4H95 A;  4QJC A;  4H98 A;  2O7P A;  3SRU X;  1BZF A;  2W9S A;  4KYA A;  2W3M A;  1KMS A;  4X5I A;  3UM5 A;  2W9G A;  3FQF A;  5HI6 A;  1LY3 A;  3DAT A;  4PSS A;  4HA9 A;  4EJ1 A;  5HT4 A;  2CD2 A;  4KBN A;  4X5G A;  1AI9 A;  3JVX A;  2AZN A;  3FRD X;  3SA2 A;  5HSU A;  4ELE A;  4FHB A;  4KM0 A;  3TQA A;  3KY8 A;  1QZF A;  2DRC A;  3EIG A;  4KY8 A;  2CIG A;  1U72 A;  2FZH A;  3F8Z A;  4G3M A;  4M6K A; 
#chains in the Genus database with same CATH homology
 3JWM A;  2C2T A;  1RE7 A;  3EEJ A;  2W3B A;  5EAJ A;  4LAE X;  2JYB A;  3IA5 A;  4LAG X;  5U27 A;  3F0U X;  1DDR A;  3GI2 A;  3FY9 X;  1DYJ A;  1DR6 A;  3IRM A;  4LEK X;  1BOZ A;  2FZI A;  6DFR A;  1DG7 A;  3OAF A;  1RX8 A;  1OHK A;  1RX7 A;  4QI9 A;  4M6J A;  1SEJ A;  1AOE A;  2LF1 A;  1DRE A;  1LY4 A;  3NZB X;  1RB2 A;  3JWK A;  3FYW X;  1CZ3 A;  2HXV A;  1YHO A;  3EEK A;  4XEC X;  4M6L A;  2W3A A;  5DFR A;  3Q1H A;  4KJL A;  4EIL A;  1KMV A;  2BLB A;  5HQZ A;  1RX1 A;  1DG8 A;  3L3R A;  3FQO A;  4X5F A;  1IA3 A;  4FGH A;  2H2Q A;  1RA8 A;  4ELF A;  4XT4 A;  1VDR A;  3QLZ A;  4KD7 A;  2HQP A;  3FQV A;  1ZDR A;  3FRF X;  4QHV A;  1DR7 A;  4Q6A A;  3SAI A;  3JW5 A;  1RB3 A;  4QLG A;  1CD2 A;  3R33 A;  4KLX A;  5CCC A;  1RD7 A;  3SGY A;  4X5H A;  1D1G A;  3DG8 A;  1RX2 A;  4X5J A;  5JG0 X;  2QK8 A;  3DAU A;  2KGK A;  1HFP A;  4XT8 A;  3JWC A;  4DFR A;  1DHF A;  5HVE A;  4TU5 X;  1J3J A;  1PDB A;  3HJ3 A;  3NXY A;  4HOE A;  3E0B A;  4DPH A;  1M79 A;  3NXO A;  3IRN A;  3RO9 A;  1JOL A;  1LUD A;  1DR2 A;  4KNE A;  3QYO A;  3CL9 A;  3NTZ A;  3QYL A;  2DHF A;  3QL0 A;  1DLS A;  3GHC A;  3EX8 A;  4KFJ A;  3DL5 A;  3F0B X;  2D5N A;  4PDJ A;  5ECC A;  3IX9 A;  1E26 A;  3S7A A;  3OCH A;  4DP3 A;  2W3W A;  1IA1 A;  1RA2 A;  2P4G A;  3INV A;  3FQC A;  3CLB A;  1OHJ A;  1DLR A;  1TDR A;  3NZC X;  1DR3 A;  4KJK A;  3ROA A;  1IA4 A;  1S3W A;  4M2X A;  2W9H A;  4NX6 A;  4HA7 A;  1DRF A;  3JW3 A;  4P66 A;  3K74 A;  4I1N A;  1DRH A;  3F0S X;  3S3V A;  3JTW A;  4H96 A;  1DR5 A;  3NXX A;  3SA1 A;  3F91 A;  1RA3 A;  4Q0E A;  3DRC A;  1PD8 A;  4RGC A;  3TQ8 A;  4M7V A;  4IXG X;  1U71 A;  2W9T A;  4XE6 X;  4PTJ A;  1RH3 A;  1DR1 A;  1JUV A;  3JWF A;  3ZPG A;  3FRB X;  4Q0D A;  1DG5 A;  1DRB A;  4M7U A;  1DHI A;  5HSR A;  1JOM A;  3NXR A;  1RX9 A;  3QLW A;  2INQ A;  4QLF A;  4H97 A;  2HM9 A;  4I13 A;  4QLE A;  2G6V A;  3NZ9 X;  3KJR A;  4EIG A;  3QLR A;  4P68 A;  1J3I A;  4DDR A;  3CD2 A;  3FRA X;  3FRE X;  1S3V A;  4IXF X;  1RX5 A;  3EEM A;  1AO8 A;  4KAK A;  4FGG A;  5HVB A;  3F0V X;  5HF2 X;  1DRA A;  1IA2 A;  3F0Q X;  3DFR A;  3VCO A;  1RA9 A;  1RA1 A;  3QLX A;  4HOG A;  4EIZ A;  4XT5 A;  3NXV A;  4PTH A;  3SRS X;  4CD2 A;  5HUI A;  5HF0 X;  3KGY A;  3FYV X;  3F0X X;  4P3R A;  3CSE A;  2FZJ A;  3TQ9 A;  3ZPC A;  3N0H A;  1DHJ A;  1DIS A;  3D84 X;  4DPD A;  1KLK A;  1M7A A;  3SRQ X;  3SR5 X;  3QFX A;  5JA3 A;  3NZ6 X;  4NX7 A;  1RC4 A;  3IA4 A;  1MVS A;  4XT7 A;  3M09 A;  2XW7 A;  4IXE D;  5HT5 A;  3FL8 A;  3LG4 A;  3QLS A;  3D80 A;  3GHW A;  3NXT A;  7DFR A;  1J3K A;  3QL3 A;  5ECX A;  2D0K A;  3SQY X;  5DXV A;  3UM6 A;  4GH8 A;  4KL9 A;  4ECK A;  2BLA A;  4ELH A;  3FQ0 A;  5U26 A;  5CC9 A;  3DGA A;  1S3U A;  4OR7 A;  3NZA X;  3NU0 A;  4PST A;  5HQY A;  1HFR A;  3FS6 A;  3QG2 A;  1DAJ A;  4ELG A;  3DL6 A;  3GYF A;  4KJJ A;  3UM8 A;  4XRB A;  5HPB A;  1U70 A;  4PSY A;  3M08 A;  1RX6 A;  1RX4 A;  3QLY A;  3IRO A;  3QGT A;  2BL9 A;  4HOF A;  3NZD A;  2ANO A;  3K2H A;  3F8Y A;  1S3Y A;  3TD8 A;  1RX3 A;  2ZZA A;  1DF7 A;  1PD9 A;  2W3V A;  4ELB A;  1DIU A;  2ANQ A;  3HBB A;  2ITH A;  2BLC A;  4XT6 A;  3FL9 A;  5E8Q A;  4KY4 A;  4QJZ D;  3KFY A;  1VJ3 A;  1DDS A;  4LAH X;  3I3R A;  3FY8 X;  3SH2 A;  3GHV A;  2GD9 A;  1DR4 A;  4Q67 A;  3SRR X;  3S9U A;  3NRR A;  4KEB A;  3EEL A;  2C2S A;  4KM2 A;  5FDA A;  3RG9 A;  1HFQ A;  3TQB A;  8DFR A;  3KJS A;  4P3Q A;  2L28 A;  2OIP A;  1MVT A;  1RF7 A;  1DYI A;  3K45 A;  1DYH A;  3FQZ A;  1M78 A;  3SRW X;  1RG7 A;  3JSU A;  4OSG A;  2B3Z A;  3I8A X;  3K47 A;  2OBC A;  1DYR A;  4G8Z X;  4G95 A;  4H95 A;  4QJC A;  4H98 A;  2O7P A;  3SRU X;  1BZF A;  2W9S A;  4KYA A;  2W3M A;  1KMS A;  4X5I A;  3UM5 A;  2W9G A;  3FQF A;  5HI6 A;  1LY3 A;  3DAT A;  4PSS A;  4HA9 A;  4EJ1 A;  5HT4 A;  2CD2 A;  4KBN A;  4X5G A;  1AI9 A;  3JVX A;  2AZN A;  3FRD X;  3SA2 A;  5HSU A;  4ELE A;  4FHB A;  4KM0 A;  3TQA A;  3KY8 A;  1QZF A;  2DRC A;  3EIG A;  4KY8 A;  2CIG A;  1U72 A;  2FZH A;  3F8Z A;  4G3M A;  4M6K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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