4HGMB

Shark ignar variable domain
Total Genus 173
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
489
structure length
478
Chain Sequence
KSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCSLVNRRPCFSALE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Shark V-NAR
publication title Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
pubmed doi rcsb
source organism Squalus acanthias
molecule tags Immune system
total genus 173
structure length 478
sequence length 489
ec nomenclature
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4hgmB02
2XVWA 4J2VA 3V08A 2VUFA 4ZBQA 4N0UD 4LUHA 2BXPA 4HGKA 1GNIA 4PO0A 4LB9A 1HK1A 4Z69A 4G03A 2BXBA 5IIXA 2BXHA 3LU6A 1E7CA 4L9KA 4F5SA 2BXCA 3B9MA 1HK4A 2XW1A 4E99A 2XW0A 2XVUA 1KW2A 1E7GA 1H9ZA 2YDFA 1N5UA 3JQZA 3B9LA 5ID7A 2BXQA 2BX8A 1AO6A 3V09A 1E7BA 5FUOA 1E7IA 1J78A 3LU8A 4IW1A 4EMXA 4LA0A 2XSIA 1E7FA 1BJ5A 4L8UA 2BXIA 2BXOA 2VDBA 2VUEA 5HOZA 1O9XA 2XVQA 2XVVA 4L9QA 1KXPD 2BXFA 5IIUA 1MA9A 4JK4A 3V03A 5DQFA 1E7HA 1HK2A 4K71A 1E7AA 4OR0A 1TF0A 4IW2A 2BXKA 1J7EA 2BXNA 4ZBRA 3LU7A 3A73A 5IJ5A 3TDLA 4OT2A 5ID9A 3CX9A 4N0FD 2BXDA 4F5UA 2BXEA 5DBYA 5GHKA 5IJEA 3JRYA 1HA2A 1UORA 4LUFA 1E7EA 4K2CA 1E78A 3SQJA 5IJFA 4F5VA 4G04A 1BM0A 4LB2A 1GNJA 2I30A 4S1YA 1BKEA 4BKEA 2BXMA 4HGMB 4F5TA 2BXGA 3UIVA 1HK5A 1HK3A 5IIHA 2I2ZA 1LOTA 5IFOA 2BXLA 2BXAA
chains in the Genus database with same CATH superfamily
2XVWA 4J2VA 3NVIA 4G01A 3MHSB 3V08A 4W4UB 1SB0A 2NNWA 2LXTA 2CKXA 2K0NA 2VUFA 1MUHA 2EFCA 4BY9C 4ZBQA 4N0UD 4LUHA 2KBZA 2BXPA 4HGKA 1GNIA 2Z8JA 4PO0A 4LB9A 1HK1A 3H37A 3BPJA 4TQ0A 5GINA 3FNMA 4DHXB 1TXUA 4Z69A 4G03A 1VZSA 4GDLB 3KJLA 4ZC6A 4MBEC 4ZCGA 4D7XA 2BXBA 3ECPA 5IIXA 2NQOA 2BXHA 2QM6A 1E7CA 3LU6A 3NVMA 4I9OA 4L9KA 2DBXA 2BXCA 3B9MA 4NAWB 1HK4A 2XW1A 4Z9OA 3VQIA 4F5SA 3W1SA 3WHRA 2XW0A 2XVUA 1KW2A 1E7GA 1H9ZA 2E0XA 2EFEA 2YDFA 1LNSA 2LQHA 1N5UA 1MIWA 2OT3A 3FWBC 3JQZA 3B9LA 4OTUA 2QHBA 5ID7A 2BXQA 2BX8A 1FOUA 3GA9L 1AO6A 5B5TA 3V09A 1E7BA 3G9KD 5FUOA 1E7IA 4OTTA 1J78A 1JNBA 2V36A 2XMOA 3LU8A 4IW1A 4EMXA 4LA0A 2XSIA 1MUSA 2EFHA 1E7FA 1BJ5A 1IJGA 2DBUA 4L8UA 2BXIA 2BXOA 2VDBA 2VUEA 5HOZA 1O9XA 3WHQA 2DYOA 2XVQA 1NT2B 3PLAA 2XVVA 4L9QA 1KXPD 4GDXA 3H3AA 2BXFA 5IIUA 1MA9A 4JK4A 3V03A 1VFIA 5DQFA 4ZUXV 5BPKA 4C31B 1E7HA 1HK2A 4K71A 1E7AA 3ICXA 1TF0A 2QMCA 4OR0A 4IW2A 1MIVA 4FIPB 4ZBKA 3M99C 2Z8KA 2BXKA 1H5WA 4GG2A 1J7EA 2BXNA 3WHSA 4ZBRA 2E0YA 3NVKA 2DYMA 4GDKB 2LOQA 2LXSA 3LU7A 2AJEA 3A73A 5IJ5A 3SIVB 2ROHA 3TDLA 2LQIA 4OT2A 5ID9A 3CX9A 4N0FD 2BXDA 4F5UA 2BXEA 3GQXA 5DBYA 5GHKA 5IJEA 3JRYA 5GIOA 1HA2A 1UORA 4FK5B 4LUFA 4TQ1A 1E7EA 4K2CA 1E78A 3SQJA 4WA6B 1KDXA 5IJFA 4F5VA 4G04A 1BM0A 4LB2A 2DBWA 1GNJA 2I30A 4DM0A 2AGHB 2EFDA 4M70B 4S1YA 1BKEA 4FJCB 4BKEA 4N3ZA 3GQUA 2Z8IA 2BXMA 3FWCC 4HGMB 2KWFA 4F5TA 5GIPA 1MIYA 2DG5A 2BXGA 3UIVA 1HK5A 5D7GA 3A75A 2JUHA 2GUTA 1HK3A 3MHHB 4E99A 5IIHA 3NMUA 2I2ZA 3KIKA 2OZBB 1LOTA 3SIUB 5IFOA 1MM8A 2BXLA 2BXAA
chains in the Genus database with same CATH topology
2XVWA 4J2VA 3NVIA 4G01A 3MHSB 3V08A 4W4UB 2NNWA 2CKXA 2VUFA 2EFCA 4BY9C 4ZBQA 4N0UD 4LUHA 2KBZA 2BXPA 4HGKA 1GNIA 2Z8JA 4PO0A 4LB9A 1HK1A 3H37A 5GINA 4TQ0A 3FNMA 4DHXB 1TXUA 4Z69A 4G03A 1VZSA 4GDLB 3KJLA 4ZC6A 4MBEC 4ZCGA 2BXBA 5IIXA 2NQOA 2BXHA 2QM6A 1E7CA 3LU6A 3NVMA 4L9KA 4NAWB 2DBXA 2BXCA 3B9MA 4Z9OA 1HK4A 2XW1A 3VQIA 4F5SA 3W1SA 3WHRA 2XW0A 2XVUA 1KW2A 1E7GA 1H9ZA 2E0XA 2EFEA 2YDFA 1LNSA 3FWBC 1N5UA 1MIWA 2OT3A 3JQZA 2QHBA 3B9LA 4OTUA 5ID7A 2BXQA 2BX8A 1FOUA 3GA9L 1AO6A 5B5TA 3V09A 1E7BA 3G9KD 5FUOA 1E7IA 4OTTA 1J78A 1JNBA 2V36A 2XMOA 3LU8A 4IW1A 4EMXA 4LA0A 2XSIA 2EFHA 1E7FA 1BJ5A 1IJGA 2DBUA 4L8UA 2BXIA 2BXOA 2VDBA 2VUEA 5HOZA 1O9XA 3WHQA 2DYOA 2XVQA 1NT2B 3PLAA 2XVVA 4L9QA 1KXPD 4GDXA 3H3AA 2BXFA 5IIUA 1MA9A 4JK4A 3V03A 1VFIA 5DQFA 4ZUXV 5BPKA 4C31B 1E7HA 1HK2A 4K71A 1E7AA 3ICXA 1TF0A 2QMCA 4OR0A 4IW2A 1MIVA 4FIPB 4ZBKA 3M99C 2Z8KA 2BXKA 1H5WA 4GG2A 1J7EA 2BXNA 3WHSA 4ZBRA 2E0YA 3NVKA 2DYMA 4GDKB 2LOQA 3LU7A 2AJEA 3A73A 5IJ5A 3SIVB 2ROHA 3TDLA 4OT2A 5ID9A 3CX9A 4N0FD 2BXDA 4F5UA 2BXEA 3GQXA 5DBYA 5GHKA 5IJEA 3JRYA 5GIOA 1HA2A 1UORA 4FK5B 4LUFA 4TQ1A 1E7EA 4K2CA 1E78A 3SQJA 4WA6B 5IJFA 4F5VA 4G04A 1BM0A 4LB2A 2DBWA 1GNJA 2I30A 2EFDA 4M70B 4S1YA 1BKEA 4FJCB 4BKEA 4N3ZA 3GQUA 2Z8IA 2BXMA 3FWCC 4HGMB 4F5TA 5GIPA 1MIYA 2DG5A 2BXGA 3UIVA 1HK5A 5D7GA 3A75A 2JUHA 1HK3A 3MHHB 4E99A 5IIHA 3NMUA 2I2ZA 3KIKA 2OZBB 1LOTA 3SIUB 5IFOA 2BXLA 2BXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XVW A;  4J2V A;  3V08 A;  2VUF A;  4ZBQ A;  4N0U D;  4LUH A;  2BXP A;  4HGK A;  1GNI A;  4PO0 A;  4LB9 A;  1HK1 A;  4Z69 A;  4G03 A;  2BXB A;  5IIX A;  2BXH A;  3LU6 A;  1E7C A;  4L9K A;  4F5S A;  2BXC A;  3B9M A;  1HK4 A;  2XW1 A;  4E99 A;  2XW0 A;  2XVU A;  1KW2 A;  1E7G A;  1H9Z A;  2YDF A;  1N5U A;  3JQZ A;  3B9L A;  5ID7 A;  2BXQ A;  2BX8 A;  1AO6 A;  3V09 A;  1E7B A;  5FUO A;  1E7I A;  1J78 A;  3LU8 A;  4IW1 A;  4EMX A;  4LA0 A;  2XSI A;  1E7F A;  1BJ5 A;  4L8U A;  2BXI A;  2BXO A;  2VDB A;  2VUE A;  5HOZ A;  1O9X A;  2XVQ A;  2XVV A;  4L9Q A;  1KXP D;  2BXF A;  5IIU A;  1MA9 A;  4JK4 A;  3V03 A;  5DQF A;  1E7H A;  1HK2 A;  4K71 A;  1E7A A;  4OR0 A;  1TF0 A;  4IW2 A;  2BXK A;  1J7E A;  2BXN A;  4ZBR A;  3LU7 A;  3A73 A;  5IJ5 A;  3TDL A;  4OT2 A;  5ID9 A;  3CX9 A;  4N0F D;  2BXD A;  4F5U A;  2BXE A;  5DBY A;  5GHK A;  5IJE A;  3JRY A;  1HA2 A;  1UOR A;  4LUF A;  1E7E A;  4K2C A;  1E78 A;  3SQJ A;  5IJF A;  4F5V A;  4G04 A;  1BM0 A;  4LB2 A;  1GNJ A;  2I30 A;  4S1Y A;  1BKE A;  4BKE A;  2BXM A;  4HGM B;  4F5T A;  2BXG A;  3UIV A;  1HK5 A;  1HK3 A;  5IIH A;  2I2Z A;  1LOT A;  5IFO A;  2BXL A;  2BXA A; 
#chains in the Genus database with same CATH topology
 2XVW A;  4J2V A;  3NVI A;  4G01 A;  3MHS B;  3V08 A;  4W4U B;  1SB0 A;  2NNW A;  2LXT A;  2CKX A;  2K0N A;  2VUF A;  1MUH A;  2EFC A;  4BY9 C;  4ZBQ A;  4N0U D;  4LUH A;  2KBZ A;  2BXP A;  4HGK A;  1GNI A;  2Z8J A;  4PO0 A;  4LB9 A;  1HK1 A;  3H37 A;  3BPJ A;  4TQ0 A;  5GIN A;  3FNM A;  4DHX B;  1TXU A;  4Z69 A;  4G03 A;  1VZS A;  4GDL B;  3KJL A;  4ZC6 A;  4MBE C;  4ZCG A;  4D7X A;  2BXB A;  3ECP A;  5IIX A;  2NQO A;  2BXH A;  2QM6 A;  1E7C A;  3LU6 A;  3NVM A;  4I9O A;  4L9K A;  2DBX A;  2BXC A;  3B9M A;  4NAW B;  1HK4 A;  2XW1 A;  4Z9O A;  3VQI A;  4F5S A;  3W1S A;  3WHR A;  2XW0 A;  2XVU A;  1KW2 A;  1E7G A;  1H9Z A;  2E0X A;  2EFE A;  2YDF A;  1LNS A;  2LQH A;  1N5U A;  1MIW A;  2OT3 A;  3FWB C;  3JQZ A;  3B9L A;  4OTU A;  2QHB A;  5ID7 A;  2BXQ A;  2BX8 A;  1FOU A;  3GA9 L;  1AO6 A;  5B5T A;  3V09 A;  1E7B A;  3G9K D;  5FUO A;  1E7I A;  4OTT A;  1J78 A;  1JNB A;  2V36 A;  2XMO A;  3LU8 A;  4IW1 A;  4EMX A;  4LA0 A;  2XSI A;  1MUS A;  2EFH A;  1E7F A;  1BJ5 A;  1IJG A;  2DBU A;  4L8U A;  2BXI A;  2BXO A;  2VDB A;  2VUE A;  5HOZ A;  1O9X A;  3WHQ A;  2DYO A;  2XVQ A;  1NT2 B;  3PLA A;  2XVV A;  4L9Q A;  1KXP D;  4GDX A;  3H3A A;  2BXF A;  5IIU A;  1MA9 A;  4JK4 A;  3V03 A;  1VFI A;  5DQF A;  4ZUX V;  5BPK A;  4C31 B;  1E7H A;  1HK2 A;  4K71 A;  1E7A A;  3ICX A;  1TF0 A;  2QMC A;  4OR0 A;  4IW2 A;  1MIV A;  4FIP B;  4ZBK A;  3M99 C;  2Z8K A;  2BXK A;  1H5W A;  4GG2 A;  1J7E A;  2BXN A;  3WHS A;  4ZBR A;  2E0Y A;  3NVK A;  2DYM A;  4GDK B;  2LOQ A;  2LXS A;  3LU7 A;  2AJE A;  3A73 A;  5IJ5 A;  3SIV B;  2ROH A;  3TDL A;  2LQI A;  4OT2 A;  5ID9 A;  3CX9 A;  4N0F D;  2BXD A;  4F5U A;  2BXE A;  3GQX A;  5DBY A;  5GHK A;  5IJE A;  3JRY A;  5GIO A;  1HA2 A;  1UOR A;  4FK5 B;  4LUF A;  4TQ1 A;  1E7E A;  4K2C A;  1E78 A;  3SQJ A;  4WA6 B;  1KDX A;  5IJF A;  4F5V A;  4G04 A;  1BM0 A;  4LB2 A;  2DBW A;  1GNJ A;  2I30 A;  4DM0 A;  2AGH B;  2EFD A;  4M70 B;  4S1Y A;  1BKE A;  4FJC B;  4BKE A;  4N3Z A;  3GQU A;  2Z8I A;  2BXM A;  3FWC C;  4HGM B;  2KWF A;  4F5T A;  5GIP A;  1MIY A;  2DG5 A;  2BXG A;  3UIV A;  1HK5 A;  5D7G A;  3A75 A;  2JUH A;  2GUT A;  1HK3 A;  3MHH B;  4E99 A;  5IIH A;  3NMU A;  2I2Z A;  3KIK A;  2OZB B;  1LOT A;  3SIU B;  5IFO A;  1MM8 A;  2BXL A;  2BXA A; 
#chains in the Genus database with same CATH homology
 2XVW A;  4J2V A;  3NVI A;  4G01 A;  3MHS B;  3V08 A;  4W4U B;  2NNW A;  2CKX A;  2VUF A;  2EFC A;  4BY9 C;  4ZBQ A;  4N0U D;  4LUH A;  2KBZ A;  2BXP A;  4HGK A;  1GNI A;  2Z8J A;  4PO0 A;  4LB9 A;  1HK1 A;  3H37 A;  5GIN A;  4TQ0 A;  3FNM A;  4DHX B;  1TXU A;  4Z69 A;  4G03 A;  1VZS A;  4GDL B;  3KJL A;  4ZC6 A;  4MBE C;  4ZCG A;  2BXB A;  5IIX A;  2NQO A;  2BXH A;  2QM6 A;  1E7C A;  3LU6 A;  3NVM A;  4L9K A;  4NAW B;  2DBX A;  2BXC A;  3B9M A;  4Z9O A;  1HK4 A;  2XW1 A;  3VQI A;  4F5S A;  3W1S A;  3WHR A;  2XW0 A;  2XVU A;  1KW2 A;  1E7G A;  1H9Z A;  2E0X A;  2EFE A;  2YDF A;  1LNS A;  3FWB C;  1N5U A;  1MIW A;  2OT3 A;  3JQZ A;  2QHB A;  3B9L A;  4OTU A;  5ID7 A;  2BXQ A;  2BX8 A;  1FOU A;  3GA9 L;  1AO6 A;  5B5T A;  3V09 A;  1E7B A;  3G9K D;  5FUO A;  1E7I A;  4OTT A;  1J78 A;  1JNB A;  2V36 A;  2XMO A;  3LU8 A;  4IW1 A;  4EMX A;  4LA0 A;  2XSI A;  2EFH A;  1E7F A;  1BJ5 A;  1IJG A;  2DBU A;  4L8U A;  2BXI A;  2BXO A;  2VDB A;  2VUE A;  5HOZ A;  1O9X A;  3WHQ A;  2DYO A;  2XVQ A;  1NT2 B;  3PLA A;  2XVV A;  4L9Q A;  1KXP D;  4GDX A;  3H3A A;  2BXF A;  5IIU A;  1MA9 A;  4JK4 A;  3V03 A;  1VFI A;  5DQF A;  4ZUX V;  5BPK A;  4C31 B;  1E7H A;  1HK2 A;  4K71 A;  1E7A A;  3ICX A;  1TF0 A;  2QMC A;  4OR0 A;  4IW2 A;  1MIV A;  4FIP B;  4ZBK A;  3M99 C;  2Z8K A;  2BXK A;  1H5W A;  4GG2 A;  1J7E A;  2BXN A;  3WHS A;  4ZBR A;  2E0Y A;  3NVK A;  2DYM A;  4GDK B;  2LOQ A;  3LU7 A;  2AJE A;  3A73 A;  5IJ5 A;  3SIV B;  2ROH A;  3TDL A;  4OT2 A;  5ID9 A;  3CX9 A;  4N0F D;  2BXD A;  4F5U A;  2BXE A;  3GQX A;  5DBY A;  5GHK A;  5IJE A;  3JRY A;  5GIO A;  1HA2 A;  1UOR A;  4FK5 B;  4LUF A;  4TQ1 A;  1E7E A;  4K2C A;  1E78 A;  3SQJ A;  4WA6 B;  5IJF A;  4F5V A;  4G04 A;  1BM0 A;  4LB2 A;  2DBW A;  1GNJ A;  2I30 A;  2EFD A;  4M70 B;  4S1Y A;  1BKE A;  4FJC B;  4BKE A;  4N3Z A;  3GQU A;  2Z8I A;  2BXM A;  3FWC C;  4HGM B;  4F5T A;  5GIP A;  1MIY A;  2DG5 A;  2BXG A;  3UIV A;  1HK5 A;  5D7G A;  3A75 A;  2JUH A;  1HK3 A;  3MHH B;  4E99 A;  5IIH A;  3NMU A;  2I2Z A;  3KIK A;  2OZB B;  1LOT A;  3SIU B;  5IFO A;  2BXL A;  2BXA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...