4HGUA

Crystal structure of galleria mellonella silk protease inhibitor 2
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
40
structure length
40
Chain Sequence
EAAVCTTEWDPVCGKDGKTYSNLCWLNEAGVGLDHEGECL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Galleria mellonella
molecule keywords Silk protease inhibitor 2
total genus 8
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2012-10-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 4hguA00
1Y1BA 1SGEI 3SEKC 1SGQI 1UUCA 3QTLD 1HPTA 1CT2I 2M5XA 1HJAI 3SGQI 2GKRI 1UVGA 5DAEA 2KMPA 2N52A 1LR9A 2F3CI 2BUSA 2KMRA 1OMUA 2QQDA 4OVOA 1TBRR 1R0RI 2ERWA 3OVOA 3HH2C 1IW4A 1DS3I 1BMOA 1SGYI 2JYYA 1FYBA 1SGNI 1LR8A 2NU0I 1TURA 1Z7KB 2B0UC 1M8BA 1CT4I 2NU3I 1PJUA 2P6AC 1N13A 1UVFA 1PPFI 1BUSA 1IY6A 2SGQI 1HDLA 2LEOA 1CGJI 2GKVA 1PCEA 2KMQA 2XRCA 3SGBI 4HGUA 2JZMA 1TGSI 2N71A 2N17A 1CGII 1M8CA 2OVOA 1OYVI 2KCXA 1LR7A 2WCYA 1TIHA 2KMOA 1SGDI 3TJQA 1IY5A 1H0ZA 1OVOA 2JXDA 1SGRI 1CT0I 1KMAA 2NU4I 2SGPI 1YU6C 2SGFI 2SGEI 2SGDI 1Y1CA 2NU2I 1CSOI 1YTPA 2QQCA 1NUBA 2ARPF 1SGPI 5JHWC 1CHOI 1AN1I 2V53A 1TUSA 1MT1A 2GKTI 1TBQR 3B4VC 4SGBI 1CE3A 1OMTA 2NU1I 4GI3C 1DS2I
chains in the Genus database with same CATH superfamily
2JA1A 7WGAA 1NXUA 1Y1BA 3TO9A 2Y0MA 1SGEI 4DNCA 2WVJA 1KBFA 1VDDA 4UXIA 3UFFA 2L8EA 3SEKC 2OD1A 2YUUA 2K9HA 1SGQI 3R5BA 2UVOA 2GIVA 3UEJA 1UUCA 3QTLD 2A20A 1HPTA 1CT2I 1V1HA 1S20A 2M5XA 1W3SA 3TOBA 5J8FA 1HJAI 2CWHA 3KY9A 1ULMA 3R5DA 4E1PA 1TBNA 1X74A 3FSYA 1P9ZA 2UZ3A 3OXGA 2CWGA 1FY7A 1MJ9A 1ULNA 2QQ0A 2DIPA 1PTRA 1Z2IA 2GKRI 1UVGA 3E2IA 5DAEA 3SGQI 1XBTA 2KMPA 2OZUA 5EX3A 2N52A 2FNFX 3TO7A 5E3QA 1LR9A 2QQEA 3D00A 3UGLA 1TOTA 3VDUA 2E5RA 2F3CI 2W0TA 1P9GA 1WGCA 2BUSA 2CWFA 2KMRA 3R5AA 4UXHA 1OMUA 2QQDA 4OVOA 1TBRR 1R0RI 2ERWA 1WTJA 2DB6A 3HH2C 3OVOA 1IW4A 3TOAA 1DS3I 1BMOA 1SGYI 2JYYA 5E3RA 1FYBA 1RFHA 1SGNI 1LR8A 2NU0I 2ORVA 1TURA 1Z7KB 1V1IA 2B0UC 2B8TA 2N1AB 2WGCA 3BJIA 1FARA 1CT4I 1M8BA 2NU3I 1K7TA 4UXJA 3OXFA 1PJUA 2P6AC 2J9RA 1N13A 5FUXA 5CCMA 1UVFA 1PPFI 1BUSA 1IY6A 2RC4A 2SGQI 5FUWA 1HDLA 2J87A 1K7UA 1CGJI 2LEOA 3UGIA 4MPIA 2GKVA 1PCEA 2RIJA 1PTQA 1ULKA 3UOEA 3GOXA 4A24A 2GVIA 5EX0A 2KMQA 1Y8FA 2XRCA 5HQ8A 2CJSC 1FAQA 3CXLA 1XA6A 3SGBI 1X4SA 4HGUA 4E1RA 2JZMA 1TGSI 2N71A 3OL0A 2QPOA 2N17A 1CGII 1M8CA 3TO6A 3UGDA 3VDPA 2OVOA 4B6DA 3FC3A 1OYVI 2KCXA 1LR7A 2WCYA 5FUVA 4L9MA 1MJBA 1TIHA 1SGDI 2KMOA 3TJQA 1IY5A 2ELIA 1H0ZA 1OVOA 1WKXA 1KBEA 2JXDA 1SGRI 1CT0I 3RU0A 1KMAA 2NU4I 2SGPI 2DKVA 1YU6C 1MJAA 2ODDA 2L7XA 2SGFI 2SGEI 2ENZA 2SGDI 5FUYA 3VE5A 1Y1CA 2LUYA 1K7VA 1TBOA 9WGAA 2NU2I 2LB7A 1CSOI 5E3PA 3MEKA 1YTPA 3OXLA 2QQCA 2YQPA 1NUBA 3QWPA 2ROWA 2PQ8A 2ARPF 1SGPI 4JCVE 1WGTA 5JHWC 1CHOI 3R5CA 1AN1I 4FKDA 2V53A 1Q9BA 1TUSA 3QAHA 1MT1A 2GKTI 1W4RA 5HI7A 1HEVA 2X52A 1TBQR 2X3TA 3B4VC 2V1CC 5CCLA 4SGBI 2V1CA 1R79A 3UEYA 3FSXA 1CE3A 1OMTA 2E73A 2NU1I 3PDNA 4GI3C 2ENNA 1DS2I 2OU2A 1XX6A 4WP4A 3E59A 1U5KA 1UHAA 2JW6A 5J8CA 2VRWB 2ORWA 4AMLA
chains in the Genus database with same CATH topology
2JA1A 1Y1BA 1SGEI 2WVJA 1KBFA 1VDDA 4UXIA 3UFFA 2L8EA 3SEKC 2OD1A 2YUUA 2K9HA 1SGQI 3UEJA 1UUCA 3QTLD 2A20A 1HPTA 1CT2I 1V1HA 2M5XA 1W3SA 1HJAI 3KY9A 4E1PA 1TBNA 1X74A 2UZ3A 3OXGA 3E2IA 3SGQI 2QQ0A 2DIPA 1PTRA 4B6DA 2GKRI 1UVGA 5DAEA 1XBTA 2KMPA 5EX3A 2N52A 2FNFX 1LR9A 2QQEA 3D00A 3UGLA 1TOTA 3VDUA 2E5RA 2F3CI 2W0TA 2BUSA 2KMRA 4UXHA 1OMUA 2QQDA 4OVOA 1TBRR 1R0RI 2ERWA 2DB6A 3HH2C 3OVOA 1IW4A 1DS3I 1BMOA 1SGYI 2JYYA 1FYBA 1RFHA 1SGNI 1LR8A 2NU0I 2ORVA 1TURA 1Z7KB 1V1IA 2B0UC 2B8TA 2N1AB 3BJIA 1FARA 1CT4I 1M8BA 2NU3I 4UXJA 3OXFA 1PJUA 2P6AC 2J9RA 1N13A 5FUXA 5CCMA 1UVFA 1PPFI 1BUSA 1IY6A 5FUWA 2SGQI 1HDLA 2J87A 2LEOA 1CGJI 3UGIA 2GKVA 1PCEA 1PTQA 3GOXA 4A24A 2GVIA 5EX0A 2KMQA 1Y8FA 2XRCA 5HQ8A 2CJSC 1FAQA 3CXLA 1XA6A 3SGBI 1X4SA 4HGUA 4E1RA 2JZMA 1TGSI 2N71A 3OL0A 2QPOA 2N17A 1CGII 1M8CA 3UGDA 3VDPA 2OVOA 3FC3A 1OYVI 2KCXA 1LR7A 2WCYA 5FUVA 4L9MA 1TIHA 2KMOA 1SGDI 3TJQA 1IY5A 2ELIA 1H0ZA 1OVOA 1KBEA 2JXDA 1SGRI 1CT0I 3RU0A 1KMAA 2NU4I 2SGPI 1YU6C 2ODDA 2SGFI 2L7XA 2SGEI 2ENZA 2SGDI 5FUYA 3VE5A 1Y1CA 2LUYA 1TBOA 2NU2I 1CSOI 3MEKA 1YTPA 3OXLA 2QQCA 2YQPA 1NUBA 3QWPA 2ROWA 2ARPF 1SGPI 4JCVE 5JHWC 1CHOI 1AN1I 4FKDA 2V53A 1TUSA 1MT1A 2GKTI 1W4RA 5HI7A 1TBQR 3B4VC 2V1CC 5CCLA 4SGBI 2V1CA 1R79A 3UEYA 1CE3A 1OMTA 2E73A 2NU1I 3PDNA 4GI3C 2ENNA 1DS2I 1XX6A 3E59A 1U5KA 2JW6A 2VRWB 2ORWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1B A;  1SGE I;  3SEK C;  1SGQ I;  1UUC A;  3QTL D;  1HPT A;  1CT2 I;  2M5X A;  1HJA I;  3SGQ I;  2GKR I;  1UVG A;  5DAE A;  2KMP A;  2N52 A;  1LR9 A;  2F3C I;  2BUS A;  2KMR A;  1OMU A;  2QQD A;  4OVO A;  1TBR R;  1R0R I;  2ERW A;  3OVO A;  3HH2 C;  1IW4 A;  1DS3 I;  1BMO A;  1SGY I;  2JYY A;  1FYB A;  1SGN I;  1LR8 A;  2NU0 I;  1TUR A;  1Z7K B;  2B0U C;  1M8B A;  1CT4 I;  2NU3 I;  1PJU A;  2P6A C;  1N13 A;  1UVF A;  1PPF I;  1BUS A;  1IY6 A;  2SGQ I;  1HDL A;  2LEO A;  1CGJ I;  2GKV A;  1PCE A;  2KMQ A;  2XRC A;  3SGB I;  4HGU A;  2JZM A;  1TGS I;  2N71 A;  2N17 A;  1CGI I;  1M8C A;  2OVO A;  1OYV I;  2KCX A;  1LR7 A;  2WCY A;  1TIH A;  2KMO A;  1SGD I;  3TJQ A;  1IY5 A;  1H0Z A;  1OVO A;  2JXD A;  1SGR I;  1CT0 I;  1KMA A;  2NU4 I;  2SGP I;  1YU6 C;  2SGF I;  2SGE I;  2SGD I;  1Y1C A;  2NU2 I;  1CSO I;  1YTP A;  2QQC A;  1NUB A;  2ARP F;  1SGP I;  5JHW C;  1CHO I;  1AN1 I;  2V53 A;  1TUS A;  1MT1 A;  2GKT I;  1TBQ R;  3B4V C;  4SGB I;  1CE3 A;  1OMT A;  2NU1 I;  4GI3 C;  1DS2 I; 
#chains in the Genus database with same CATH topology
 2JA1 A;  7WGA A;  1NXU A;  1Y1B A;  3TO9 A;  2Y0M A;  1SGE I;  4DNC A;  2WVJ A;  1KBF A;  1VDD A;  4UXI A;  3UFF A;  2L8E A;  3SEK C;  2OD1 A;  2YUU A;  2K9H A;  1SGQ I;  3R5B A;  2UVO A;  2GIV A;  3UEJ A;  1UUC A;  3QTL D;  2A20 A;  1HPT A;  1CT2 I;  1V1H A;  1S20 A;  2M5X A;  1W3S A;  3TOB A;  5J8F A;  1HJA I;  2CWH A;  3KY9 A;  1ULM A;  3R5D A;  4E1P A;  1TBN A;  1X74 A;  3FSY A;  1P9Z A;  2UZ3 A;  3OXG A;  2CWG A;  1FY7 A;  1MJ9 A;  1ULN A;  2QQ0 A;  2DIP A;  1PTR A;  1Z2I A;  2GKR I;  1UVG A;  3E2I A;  5DAE A;  3SGQ I;  1XBT A;  2KMP A;  2OZU A;  5EX3 A;  2N52 A;  2FNF X;  3TO7 A;  5E3Q A;  1LR9 A;  2QQE A;  3D00 A;  3UGL A;  1TOT A;  3VDU A;  2E5R A;  2F3C I;  2W0T A;  1P9G A;  1WGC A;  2BUS A;  2CWF A;  2KMR A;  3R5A A;  4UXH A;  1OMU A;  2QQD A;  4OVO A;  1TBR R;  1R0R I;  2ERW A;  1WTJ A;  2DB6 A;  3HH2 C;  3OVO A;  1IW4 A;  3TOA A;  1DS3 I;  1BMO A;  1SGY I;  2JYY A;  5E3R A;  1FYB A;  1RFH A;  1SGN I;  1LR8 A;  2NU0 I;  2ORV A;  1TUR A;  1Z7K B;  1V1I A;  2B0U C;  2B8T A;  2N1A B;  2WGC A;  3BJI A;  1FAR A;  1CT4 I;  1M8B A;  2NU3 I;  1K7T A;  4UXJ A;  3OXF A;  1PJU A;  2P6A C;  2J9R A;  1N13 A;  5FUX A;  5CCM A;  1UVF A;  1PPF I;  1BUS A;  1IY6 A;  2RC4 A;  2SGQ I;  5FUW A;  1HDL A;  2J87 A;  1K7U A;  1CGJ I;  2LEO A;  3UGI A;  4MPI A;  2GKV A;  1PCE A;  2RIJ A;  1PTQ A;  1ULK A;  3UOE A;  3GOX A;  4A24 A;  2GVI A;  5EX0 A;  2KMQ A;  1Y8F A;  2XRC A;  5HQ8 A;  2CJS C;  1FAQ A;  3CXL A;  1XA6 A;  3SGB I;  1X4S A;  4HGU A;  4E1R A;  2JZM A;  1TGS I;  2N71 A;  3OL0 A;  2QPO A;  2N17 A;  1CGI I;  1M8C A;  3TO6 A;  3UGD A;  3VDP A;  2OVO A;  4B6D A;  3FC3 A;  1OYV I;  2KCX A;  1LR7 A;  2WCY A;  5FUV A;  4L9M A;  1MJB A;  1TIH A;  1SGD I;  2KMO A;  3TJQ A;  1IY5 A;  2ELI A;  1H0Z A;  1OVO A;  1WKX A;  1KBE A;  2JXD A;  1SGR I;  1CT0 I;  3RU0 A;  1KMA A;  2NU4 I;  2SGP I;  2DKV A;  1YU6 C;  1MJA A;  2ODD A;  2L7X A;  2SGF I;  2SGE I;  2ENZ A;  2SGD I;  5FUY A;  3VE5 A;  1Y1C A;  2LUY A;  1K7V A;  1TBO A;  9WGA A;  2NU2 I;  2LB7 A;  1CSO I;  5E3P A;  3MEK A;  1YTP A;  3OXL A;  2QQC A;  2YQP A;  1NUB A;  3QWP A;  2ROW A;  2PQ8 A;  2ARP F;  1SGP I;  4JCV E;  1WGT A;  5JHW C;  1CHO I;  3R5C A;  1AN1 I;  4FKD A;  2V53 A;  1Q9B A;  1TUS A;  3QAH A;  1MT1 A;  2GKT I;  1W4R A;  5HI7 A;  1HEV A;  2X52 A;  1TBQ R;  2X3T A;  3B4V C;  2V1C C;  5CCL A;  4SGB I;  2V1C A;  1R79 A;  3UEY A;  3FSX A;  1CE3 A;  1OMT A;  2E73 A;  2NU1 I;  3PDN A;  4GI3 C;  2ENN A;  1DS2 I;  2OU2 A;  1XX6 A;  4WP4 A;  3E59 A;  1U5K A;  1UHA A;  2JW6 A;  5J8C A;  2VRW B;  2ORW A;  4AML A; 
#chains in the Genus database with same CATH homology
 2JA1 A;  1Y1B A;  1SGE I;  2WVJ A;  1KBF A;  1VDD A;  4UXI A;  3UFF A;  2L8E A;  3SEK C;  2OD1 A;  2YUU A;  2K9H A;  1SGQ I;  3UEJ A;  1UUC A;  3QTL D;  2A20 A;  1HPT A;  1CT2 I;  1V1H A;  2M5X A;  1W3S A;  1HJA I;  3KY9 A;  4E1P A;  1TBN A;  1X74 A;  2UZ3 A;  3OXG A;  3E2I A;  3SGQ I;  2QQ0 A;  2DIP A;  1PTR A;  4B6D A;  2GKR I;  1UVG A;  5DAE A;  1XBT A;  2KMP A;  5EX3 A;  2N52 A;  2FNF X;  1LR9 A;  2QQE A;  3D00 A;  3UGL A;  1TOT A;  3VDU A;  2E5R A;  2F3C I;  2W0T A;  2BUS A;  2KMR A;  4UXH A;  1OMU A;  2QQD A;  4OVO A;  1TBR R;  1R0R I;  2ERW A;  2DB6 A;  3HH2 C;  3OVO A;  1IW4 A;  1DS3 I;  1BMO A;  1SGY I;  2JYY A;  1FYB A;  1RFH A;  1SGN I;  1LR8 A;  2NU0 I;  2ORV A;  1TUR A;  1Z7K B;  1V1I A;  2B0U C;  2B8T A;  2N1A B;  3BJI A;  1FAR A;  1CT4 I;  1M8B A;  2NU3 I;  4UXJ A;  3OXF A;  1PJU A;  2P6A C;  2J9R A;  1N13 A;  5FUX A;  5CCM A;  1UVF A;  1PPF I;  1BUS A;  1IY6 A;  5FUW A;  2SGQ I;  1HDL A;  2J87 A;  2LEO A;  1CGJ I;  3UGI A;  2GKV A;  1PCE A;  1PTQ A;  3GOX A;  4A24 A;  2GVI A;  5EX0 A;  2KMQ A;  1Y8F A;  2XRC A;  5HQ8 A;  2CJS C;  1FAQ A;  3CXL A;  1XA6 A;  3SGB I;  1X4S A;  4HGU A;  4E1R A;  2JZM A;  1TGS I;  2N71 A;  3OL0 A;  2QPO A;  2N17 A;  1CGI I;  1M8C A;  3UGD A;  3VDP A;  2OVO A;  3FC3 A;  1OYV I;  2KCX A;  1LR7 A;  2WCY A;  5FUV A;  4L9M A;  1TIH A;  2KMO A;  1SGD I;  3TJQ A;  1IY5 A;  2ELI A;  1H0Z A;  1OVO A;  1KBE A;  2JXD A;  1SGR I;  1CT0 I;  3RU0 A;  1KMA A;  2NU4 I;  2SGP I;  1YU6 C;  2ODD A;  2SGF I;  2L7X A;  2SGE I;  2ENZ A;  2SGD I;  5FUY A;  3VE5 A;  1Y1C A;  2LUY A;  1TBO A;  2NU2 I;  1CSO I;  3MEK A;  1YTP A;  3OXL A;  2QQC A;  2YQP A;  1NUB A;  3QWP A;  2ROW A;  2ARP F;  1SGP I;  4JCV E;  5JHW C;  1CHO I;  1AN1 I;  4FKD A;  2V53 A;  1TUS A;  1MT1 A;  2GKT I;  1W4R A;  5HI7 A;  1TBQ R;  3B4V C;  2V1C C;  5CCL A;  4SGB I;  2V1C A;  1R79 A;  3UEY A;  1CE3 A;  1OMT A;  2E73 A;  2NU1 I;  3PDN A;  4GI3 C;  2ENN A;  1DS2 I;  1XX6 A;  3E59 A;  1U5K A;  2JW6 A;  2VRW B;  2ORW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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