4HI8B

Structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain collected at high energy, wavelength 0.32800
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
72
structure length
72
Chain Sequence
SENLYFQGSASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Integrin-linked protein kinase
total genus 12
structure length 72
sequence length 72
ec nomenclature
pdb deposition date 2012-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 4hi8B00
1NYPA 1QLIA 4KFZA 2XJZA 2D8YA 2L6YB 2DLOA 2MBVA 2D8XA 1CXXA 3IXEB 3F6QB 2LXDA 2LZUA 2IYBE 1B8TA 1U5SB 1X62A 2XQNT 2L6ZC 1A7IA 2MIUA 1V6GA 4HI8B 2O13A 2DARA 3MMKA 2CUPA 2YPAC 1X6AA 1WYHA 1X3HA 1J2OA 1X4LA 1RUTX 1IMLA 1IBIA 1X64A 2DJ7A 2CURA 1WIGA 2D8ZA 2O10A 4JCJA 2CORA 2JTNA 2XJYA 2L4ZA 2EGQA 1M3VA 1CTLA 1G47A 1X61A 4HI9B 2CO8A 2CUQA 1X68A 2KBXB 1X63A 2EHEA 2CU8A 2DFYC
chains in the Genus database with same CATH superfamily
2D8YA 4BHWA 2D8XA 2LXDA 1U5SB 2XQNT 5FY1A 1A7IA 2MIUA 4HI8B 1J2OA 5LKUA 1IMLA 1X64A 2DJ7A 1WIGA 2CORA 2CUQA 1X68A 1X63A 3ZLIA 5FXXA 1NYPA 5LKXA 5LKZA 4KFZA 3NIMA 5FXZA 5FY7A 4UF0B 2LZUA 3NISA 1V6GA 3NILA 1X3HA 1X4LA 1RUTX 5FP3A 1IBIA 2CURA 2D8ZA 1M3VA 3NIKA 4HI9B 4EYUA 4UF0A 2XJZA 3NIJA 2DLOA 2MBVA 5A1LA 3IXEB 1B8TA 2IYBE 3NIHA 1X62A 2O13A 2DARA 4EZHA 5FYMA 1X6AA 4JCJA 2O10A 2L4ZA 1X61A 2CO8A 5LKTA 1QLIA 3AVSA 2L6YB 2XUEA 1CXXA 3NINA 3F6QB 3ZPOA 2L6ZC 5FXWA 3MMKA 2CUPA 2YPAC 1WYHA 3AVRA 4ASKA 5FY0A 2JTNA 2XJYA 2EGQA 1CTLA 1G47A 2KBXB 4EZ4A 5FXVA 2EHEA 2CU8A 2DFYC
chains in the Genus database with same CATH topology
2D8YA 4BHWA 2D8XA 2LXDA 1U5SB 2XQNT 5FY1A 1A7IA 2MIUA 4HI8B 1J2OA 5LKUA 1IMLA 1X64A 2DJ7A 1WIGA 2CORA 2CUQA 1X68A 1X63A 3ZLIA 5FXXA 1NYPA 5LKXA 5LKZA 4KFZA 3NIMA 5FXZA 5FY7A 4UF0B 2LZUA 3NISA 1V6GA 3NILA 1X3HA 1X4LA 1RUTX 5FP3A 1IBIA 2CURA 2D8ZA 1M3VA 3NIKA 4HI9B 4EYUA 4UF0A 2XJZA 3NIJA 2DLOA 2MBVA 5A1LA 3IXEB 1B8TA 2IYBE 3NIHA 1X62A 2O13A 2DARA 4EZHA 5FYMA 1X6AA 4JCJA 2O10A 2L4ZA 1X61A 2CO8A 5LKTA 1QLIA 3AVSA 2L6YB 2XUEA 1CXXA 3NINA 3F6QB 3ZPOA 2L6ZC 5FXWA 3MMKA 2CUPA 2YPAC 1WYHA 3AVRA 4ASKA 5FY0A 2JTNA 2XJYA 2EGQA 1CTLA 1G47A 2KBXB 4EZ4A 5FXVA 2EHEA 2CU8A 2DFYC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NYP A;  1QLI A;  4KFZ A;  2XJZ A;  2D8Y A;  2L6Y B;  2DLO A;  2MBV A;  2D8X A;  1CXX A;  3IXE B;  3F6Q B;  2LXD A;  2LZU A;  2IYB E;  1B8T A;  1U5S B;  1X62 A;  2XQN T;  2L6Z C;  1A7I A;  2MIU A;  1V6G A;  4HI8 B;  2O13 A;  2DAR A;  3MMK A;  2CUP A;  2YPA C;  1X6A A;  1WYH A;  1X3H A;  1J2O A;  1X4L A;  1RUT X;  1IML A;  1IBI A;  1X64 A;  2DJ7 A;  2CUR A;  1WIG A;  2D8Z A;  2O10 A;  4JCJ A;  2COR A;  2JTN A;  2XJY A;  2L4Z A;  2EGQ A;  1M3V A;  1CTL A;  1G47 A;  1X61 A;  4HI9 B;  2CO8 A;  2CUQ A;  1X68 A;  2KBX B;  1X63 A;  2EHE A;  2CU8 A;  2DFY C; 
#chains in the Genus database with same CATH topology
 2D8Y A;  4BHW A;  2D8X A;  2LXD A;  1U5S B;  2XQN T;  5FY1 A;  1A7I A;  2MIU A;  4HI8 B;  1J2O A;  5LKU A;  1IML A;  1X64 A;  2DJ7 A;  1WIG A;  2COR A;  2CUQ A;  1X68 A;  1X63 A;  3ZLI A;  5FXX A;  1NYP A;  5LKX A;  5LKZ A;  4KFZ A;  3NIM A;  5FXZ A;  5FY7 A;  4UF0 B;  2LZU A;  3NIS A;  1V6G A;  3NIL A;  1X3H A;  1X4L A;  1RUT X;  5FP3 A;  1IBI A;  2CUR A;  2D8Z A;  1M3V A;  3NIK A;  4HI9 B;  4EYU A;  4UF0 A;  2XJZ A;  3NIJ A;  2DLO A;  2MBV A;  5A1L A;  3IXE B;  1B8T A;  2IYB E;  3NIH A;  1X62 A;  2O13 A;  2DAR A;  4EZH A;  5FYM A;  1X6A A;  4JCJ A;  2O10 A;  2L4Z A;  1X61 A;  2CO8 A;  5LKT A;  1QLI A;  3AVS A;  2L6Y B;  2XUE A;  1CXX A;  3NIN A;  3F6Q B;  3ZPO A;  2L6Z C;  5FXW A;  3MMK A;  2CUP A;  2YPA C;  1WYH A;  3AVR A;  4ASK A;  5FY0 A;  2JTN A;  2XJY A;  2EGQ A;  1CTL A;  1G47 A;  2KBX B;  4EZ4 A;  5FXV A;  2EHE A;  2CU8 A;  2DFY C; 
#chains in the Genus database with same CATH homology
 2D8Y A;  4BHW A;  2D8X A;  2LXD A;  1U5S B;  2XQN T;  5FY1 A;  1A7I A;  2MIU A;  4HI8 B;  1J2O A;  5LKU A;  1IML A;  1X64 A;  2DJ7 A;  1WIG A;  2COR A;  2CUQ A;  1X68 A;  1X63 A;  3ZLI A;  5FXX A;  1NYP A;  5LKX A;  5LKZ A;  4KFZ A;  3NIM A;  5FXZ A;  5FY7 A;  4UF0 B;  2LZU A;  3NIS A;  1V6G A;  3NIL A;  1X3H A;  1X4L A;  1RUT X;  5FP3 A;  1IBI A;  2CUR A;  2D8Z A;  1M3V A;  3NIK A;  4HI9 B;  4EYU A;  4UF0 A;  2XJZ A;  3NIJ A;  2DLO A;  2MBV A;  5A1L A;  3IXE B;  1B8T A;  2IYB E;  3NIH A;  1X62 A;  2O13 A;  2DAR A;  4EZH A;  5FYM A;  1X6A A;  4JCJ A;  2O10 A;  2L4Z A;  1X61 A;  2CO8 A;  5LKT A;  1QLI A;  3AVS A;  2L6Y B;  2XUE A;  1CXX A;  3NIN A;  3F6Q B;  3ZPO A;  2L6Z C;  5FXW A;  3MMK A;  2CUP A;  2YPA C;  1WYH A;  3AVR A;  4ASK A;  5FY0 A;  2JTN A;  2XJY A;  2EGQ A;  1CTL A;  1G47 A;  2KBX B;  4EZ4 A;  5FXV A;  2EHE A;  2CU8 A;  2DFY C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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