4HJQA

Shp-1 catalytic domain wpd loop closed
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
281
structure length
281
Chain Sequence
GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title SHP Family Protein Tyrosine Phosphatases Adopt Canonical Active-Site Conformations in the Apo and Phosphate-Bound States.
pubmed rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 6
total genus 101
structure length 281
sequence length 281
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2012-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4hjqA00
4JMKA 1PTTA 3V0IA 2QDPA 4HJQA 2H4KA 2AZRA 3NMEA 3V0GA 2H4VA 3D1HA 1AAXA 3ZM2A 3O4TA 2JJDA 2QBSA 4J51A 2FJMA 1NZ7A 2HCMA 4WU3A 1P15A 2VEXA 1C83A 3QCMA 4GS0A 1OETA 4ZN5A 1WCHA 2QDCA 4NWGA 2NT2A 2Q47A 5K25A 1ZCKA 2B4PA 3OMHA 3QKPA 2H02A 4DGXA 2HC2A 3QCGA 3QCFA 5KA3A 1Q6PA 1ZCLA 2ESBA 5K9WA 1YWFA 5K23A 2B4OA 5KA9A 1PTUA 1XXVA 1C85A 2I3UA 4AZ1A 2BGEA 2H4GA 4WOHA 5BUGA 3ZM1A 1Q6JA 2DXPA 2F6YA 1R6HA 4NWFA 4HJPA 1WAXA 4OHEA 2I4GA 1G4WR 5MMZB 2QCTA 1G4US 1ZC0A 4ZI4A 1D5RA 4MBBA 5I6VA 2C7SA 5BX1A 3D1OA 2NLKA 1LYVA 3D44A 3V0JA 3H2XA 4ZRTA 2CM2A 4GFVA 2HB1A 2QEPA 2I4EA 3D9CA 2OC3A 1OHCA 4GFUA 4S0GA 1Q1MA 2OOQA 1I9TA 2PSZA 2J17A 2QBPA 1YTWA 2I6JA 1Q6SA 3QCIA 4JNBA 4OHLA 2BZLA 4RHGA 2CM3A 2I3RA 2CMCA 1OHEA 3D1QA 2NV5A 3QCCA 4RH5A 2F71A 3S3EA 5HDEA 1NO6A 2HY3A 1QZ0A 2YDUA 4QAPA 2NZ6A 5GTJA 3D42A 4GRZA 1I57A 3AWEA 2ZMMA 3BRHA 4NYHA 5AWXA 2OUDA 3F9BA 4GWFA 5IBSA 2B49A 3S4EA 3QCLA 1BZJA 1WRMA 2B4SA 2I6OA 4Y14A 5KACA 2QBRA 2VEYA 4QAHA 4R30A 1JLNA 1GFYA 3QCNA 1G1GA 1PTVA 2HXPA 2F46A 2CFVA 3I36A 1T4JA 4WU2A 1NWEA 3S4OA 3BM8A 1NWLA 4YR8B 1A5YA 3F99A 3QCDA 4H1OA 4R0SA 1L8KA 3S3KA 3RGQA 1FPRA 3QCKA 3A5JA 1QXKA 1C88A 4OHDA 2M3VA 3AWFA 1PYNA 3ZMQA 2B3OA 1C84A 2CMBA 5M43A 3RGOA 4GRYA 2WGPA 1ZZWA 2VEWA 4RKKA 2CNHA 2RF6A 1YPTA 2PT0A 5BZXA 2F6VA 2B4UA 3SMEA 4KYQA 3MOWA 4D3QA 3V0DA 4BPCA 1FQ1A 3A5KA 2C46A 3B7OA 4ERCA 1YZ4A 1I9SA 5EHPA 1OHDA 3U96A 1C86A 2H03A 1Q6MA 3CWEA 2FH7A 5KABA 1G1FA 4IKCA 2MBCA 4R0TA 1OESA 3QCHA 2A3KA 4KI9A 5K22A 1ONYA 3EU0A 4Z6BA 1V3AA 1YTNA 1T48A 2GP0A 1YFOA 2F6FA 2F6TA 2PQ5A 4RI5A 3EZZA 2IMGA 4OHHA 5KA7A 2I75A 3V0HA 2CNFA 4RI4A 4H34A 2FJNA 1YGUA 1T49A 3PS5A 2GWOA 1C87A 5K9VA 1KAKA 1PA1A 1Q6TA 2QBQA 2HNPA 4GE6A 2R0BA 1XBOA 3QCBA 2BIJA 4D3RA 3F41A 1NL9A 3ZM0A 3ZV2A 4RDDA 2QDMA 2I5XA 3F9AA 1BZCA 3O4UA 1U24A 4QUMA 2PBNA 2Y96A 4D3PA 1PXHA 3ZMPA 2B07A 5KA4A 5KA8A 1RPMA 5KAAA 4JBCA 4TVVA 1OEMX 2A8BA 3EMUA 2CNEA 1YGRA 3MOZA 2CNIA 1EENA 3SR9A 1OEUA 2I6IA 4NNDA 5KA2A 2E0TA 3CM3A 2BGDA 1OEOX 1VHRA 1XXPA 3O3LA 1G7GA 2VEUA 1PA9A 2CNGA 1JF7A 1NNYA 3V0FA 2NTAA 4ICZA 2HNQA 4QBWA 3RO1A 3S3HA 1KAVA 4OHIA 4KYRA 3S3FA 2CMAA 5KA0A 1FPZA 2I6PA 2VEVA 3BLTA 1YN9A 3M4UA 2AHSA 5KA1A 3N0AA 3QCJA 4WTYA 5EHRA 4BJOA 1PH0A 1MKPA 3LJ8A 3QKQA 2HC1A 2J16B 4QUNA 4B04A 4HRFA 4QBEA 2F70A 2Y2FA 3MMJA 1GWZA 3AWGA 3GXGA 1BZHA 2OZ5A 4Y2EA 4GE2A 2CJZA 3ZM3A 2CM8A 2GJTA 2PI7A 5J8RA 2H04A 1ECVA 5K24A 2G59A 3OLRA 1X24A 1U26A 2NT7A 4JMJA 4PYHA 3O5XA 3BLUA 1RXDA 2G6ZA 2PA5A 1LQFA 4YAAA 2I1YA 2F6WA 5BZZA 4NX8A 1LARA 4GE5A 5LXQB 3QCEA 2P6XA 2I42A 2QCJA 1PTYA 2Q05A 3EB1A 1G1HA 2BV5A 3EAXA 2I4HA 1EEOA 4I8NA 3V0EA 4DGPA 4RH9A 2P4DA 5IBMA 3F81A 2SHPA 3I80A 3I7ZA 1ONZA 1L8GA 1G7FA 1U25A 2ZN7A 2CM7A 1M3GA 3O4SA 1J4XA 3GXHA 2F6ZA 1SUGA 1YTSA 1XRIA 4PVGA 2I6MA 3RZ2A 5KADA 2HVLA 1XM2A 1OEVA 2J16A 1Q6NA
chains in the Genus database with same CATH superfamily
4JMKA 1PTTA 3V0IA 2QDPA 4HJQA 2H4KA 2AZRA 3NMEA 3V0GA 2H4VA 3D1HA 1AAXA 3ZM2A 3O4TA 2JJDA 2QBSA 2F00A 4J51A 2FJMA 1NZ7A 2HCMA 4WU3A 1P15A 2VEXA 1C83A 2UAGA 3QCMA 2XJAA 2Y67A 4GS0A 1OETA 4CVKA 4ZN5A 1WCHA 2QDCA 4NWGA 1UAGA 2NT2A 2Q47A 2Y1OA 5K25A 1ZCKA 2B4PA 3OMHA 3QKPA 2H02A 4DGXA 2HC2A 3QCGA 3QCFA 5KA3A 1Q6PA 1ZCLA 2ESBA 5K9WA 1YWFA 1P3DA 5K23A 2B4OA 5KA9A 1W78A 1PTUA 1XXVA 1C85A 2I3UA 4AZ1A 2BGEA 2H4GA 4WOHA 5BUGA 3ZM1A 1Q6JA 2DXPA 2F6YA 1R6HA 4NWFA 4HJPA 1WAXA 4OHEA 4BUBA 2GC5A 2I4GA 2WTZA 1G4WR 5MMZB 2QCTA 1G4US 1ZC0A 4ZI4A 1D5RA 4MBBA 5A5FA 5I6VA 2C7SA 4C13A 5BX1A 3D1OA 2NLKA 1LYVA 3D44A 1P31A 3V0JA 3H2XA 5A5EA 2AM2A 4ZRTA 2CM2A 3NRSA 3ZM5A 4GFVA 2HB1A 2QEPA 1GQQA 2I4EA 2Y66A 3D9CA 2OC3A 1OHCA 4GFUA 4S0GA 1Q1MA 2OOQA 1I9TA 2PSZA 2J17A 2QBPA 1YTWA 2I6JA 1Q6SA 3QCIA 4JNBA 1E8CA 2BZLA 4OHLA 4RHGA 2CM3A 2I3RA 2CMCA 3HN7A 1OHEA 3D1QA 2NV5A 3QCCA 4RH5A 2F71A 3S3EA 5HDEA 1NO6A 2HY3A 1QZ0A 2YDUA 4QAPA 2NZ6A 5GTJA 2JFHA 3D42A 4GRZA 1I57A 3AWEA 2ZMMA 3BRHA 4NYHA 5AWXA 2OUDA 1J6UA 3F9BA 4GWFA 5IBSA 2B49A 3S4EA 3QCLA 1E0DA 1BZJA 1WRMA 2B4SA 2I6OA 4Y14A 3MVNA 5KACA 2QBRA 2VEYA 4QAHA 4R30A 1JLNA 2X5OA 1GFYA 3QCNA 2JFFA 1GQYA 1G1GA 2GC6A 1PTVA 2HXPA 2UUPA 2F46A 4HV4A 2CFVA 3I36A 1T4JA 4WU2A 2UUOA 4QF5A 1NWEA 3S4OA 3BM8A 1NWLA 4YR8B 1A5YA 3ZM6A 3F99A 3QCDA 4H1OA 4R0SA 1L8KA 3S3KA 3RGQA 1FPRA 4CVLA 4UAGA 3QCKA 3A5JA 1QXKA 1C88A 4OHDA 2M3VA 3AWFA 1PYNA 3ZMQA 2B3OA 1C84A 2CMBA 5M43A 3RGOA 4GRYA 2WGPA 1ZZWA 2VEWA 4RKKA 2CNHA 2RF6A 2VORA 1YPTA 2PT0A 2VTEA 5BZXA 2F6VA 3UAGA 2B4UA 3SMEA 4KYQA 2VTDA 3MOWA 4D3QA 3V0DA 4BPCA 4QDIA 1FQ1A 3A5KA 2C46A 3B7OA 4ERCA 1YZ4A 4BUCA 1I9SA 5EHPA 1OHDA 3U96A 1JBWA 2XPCA 3ZL8A 1C86A 2H03A 1Q6MA 3CWEA 2FH7A 5KABA 1G1FA 4IKCA 2MBCA 4R0TA 1OESA 3QCHA 2A3KA 4KI9A 5K22A 1ONYA 3EU0A 4Z6BA 1V3AA 1YTNA 1T48A 2GP0A 1YFOA 2F6FA 2AM1A 2F6TA 2PQ5A 2Y68A 4RI5A 3EZZA 2IMGA 4OHHA 5KA7A 2I75A 3V0HA 2CNFA 4RI4A 4H34A 2FJNA 1YGUA 1T49A 3PS5A 2GWOA 1C87A 1EEHA 5K9VA 1KAKA 1PA1A 1Q6TA 2QBQA 2HNPA 4GE6A 2R0BA 1XBOA 3QCBA 2BIJA 4D3RA 3F41A 1NL9A 3ZM0A 3ZV2A 4RDDA 2QDMA 2I5XA 3F9AA 1BZCA 3O4UA 1U24A 4QUMA 2PBNA 2Y96A 4D3PA 1PXHA 3ZMPA 2B07A 5KA4A 5KA8A 1RPMA 5KAAA 4JBCA 4TVVA 1OEMX 2A8BA 3EMUA 2CNEA 1YGRA 3MOZA 2CNIA 1EENA 1W7KA 3SR9A 1O5ZA 1OEUA 2I6IA 4NNDA 5KA2A 2E0TA 3CM3A 2BGDA 1OEOX 1VHRA 1XXPA 3O3LA 1G7GA 2VEUA 4C12A 1PA9A 2CNGA 1JF7A 3N2AA 1NNYA 3V0FA 2NTAA 4ICZA 2HNQA 4QBWA 3RO1A 3S3HA 1KAVA 4OHIA 1JBVA 4KYRA 3S3FA 2CMAA 5KA0A 1FPZA 2I6PA 4ZIYA 2VEVA 3BLTA 1YN9A 3M4UA 2AHSA 5KA1A 3N0AA 3QCJA 4WTYA 5EHRA 4BJOA 1PH0A 1MKPA 3LJ8A 3QKQA 2HC1A 2J16B 4QUNA 4B04A 4HRFA 4QBEA 2F70A 2Y2FA 3MMJA 2JFGA 1GWZA 3AWGA 2WJPA 3GXGA 1BZHA 2OZ5A 4Y2EA 4GE2A 2CJZA 3LK7A 3ZM3A 2CM8A 2GJTA 2PI7A 5J8RA 2H04A 1ECVA 5K24A 2G59A 3OLRA 1X24A 4CVMA 1U26A 2NT7A 4JMJA 4PYHA 3O5XA 2VOSA 3BLUA 1RXDA 2G6ZA 2PA5A 1LQFA 4YAAA 2I1YA 2F6WA 5BZZA 4NX8A 1LARA 4GE5A 5LXQB 3QCEA 2P6XA 2I42A 2QCJA 1PTYA 2Q05A 3EB1A 2GCAA 1G1HA 2BV5A 3PYZA 3EAXA 2I4HA 2GCBA 1EEOA 4I8NA 3V0EA 4DGPA 4RH9A 2P4DA 5IBMA 1GG4A 3F81A 3QCZA 2SHPA 3I80A 3I7ZA 1ONZA 1L8GA 1G7FA 1U25A 2ZN7A 2CM7A 1M3GA 3O4SA 1J4XA 1FGSA 3GXHA 2F6ZA 1SUGA 1YTSA 1XRIA 4PVGA 2I6MA 3RZ2A 5KADA 2HVLA 1XM2A 1OEVA 2J16A 1Q6NA
chains in the Genus database with same CATH topology
4JMKA 1PTTA 3V0IA 2QDPA 4HJQA 2H4KA 2AZRA 3NMEA 3V0GA 2H4VA 3D1HA 1AAXA 3ZM2A 3O4TA 2JJDA 2QBSA 4J51A 2FJMA 1NZ7A 2HCMA 4WU3A 1P15A 2VEXA 1C83A 3QCMA 4GS0A 1OETA 4ZN5A 1WCHA 2QDCA 4NWGA 2NT2A 2Q47A 5K25A 1ZCKA 2B4PA 3OMHA 3QKPA 2H02A 4DGXA 2HC2A 3QCGA 3QCFA 5KA3A 1Q6PA 1ZCLA 2ESBA 5K9WA 1YWFA 5K23A 2B4OA 5KA9A 1PTUA 1XXVA 1C85A 2I3UA 4AZ1A 2BGEA 2H4GA 4WOHA 5BUGA 3ZM1A 1Q6JA 2DXPA 2F6YA 1R6HA 4NWFA 4HJPA 1WAXA 4OHEA 2I4GA 1G4WR 5MMZB 2QCTA 1G4US 1ZC0A 4ZI4A 1D5RA 4MBBA 5I6VA 2C7SA 5BX1A 3D1OA 2NLKA 1LYVA 3D44A 3V0JA 3H2XA 4ZRTA 2CM2A 4GFVA 2HB1A 2QEPA 2I4EA 3D9CA 2OC3A 1OHCA 4GFUA 4S0GA 1Q1MA 2OOQA 1I9TA 2PSZA 2J17A 2QBPA 1YTWA 2I6JA 1Q6SA 3QCIA 4JNBA 4OHLA 2BZLA 4RHGA 2CM3A 2I3RA 2CMCA 1OHEA 3D1QA 2NV5A 3QCCA 4RH5A 2F71A 3S3EA 5HDEA 1NO6A 2HY3A 1QZ0A 2YDUA 4QAPA 2NZ6A 5GTJA 3D42A 4GRZA 1I57A 3AWEA 2ZMMA 3BRHA 4NYHA 5AWXA 2OUDA 3F9BA 4GWFA 5IBSA 2B49A 3S4EA 3QCLA 1BZJA 1WRMA 2B4SA 2I6OA 4Y14A 5KACA 2QBRA 2VEYA 4QAHA 4R30A 1JLNA 1GFYA 3QCNA 1G1GA 1PTVA 2HXPA 2F46A 2CFVA 3I36A 1T4JA 4WU2A 1NWEA 3S4OA 3BM8A 1NWLA 4YR8B 1A5YA 3F99A 3QCDA 4H1OA 4R0SA 1L8KA 3S3KA 3RGQA 1FPRA 3QCKA 3A5JA 1QXKA 1C88A 4OHDA 2M3VA 3AWFA 1PYNA 3ZMQA 2B3OA 1C84A 2CMBA 5M43A 3RGOA 4GRYA 2WGPA 1ZZWA 2VEWA 4RKKA 2CNHA 2RF6A 1YPTA 2PT0A 5BZXA 2F6VA 2B4UA 3SMEA 4KYQA 3MOWA 4D3QA 3V0DA 4BPCA 1FQ1A 3A5KA 2C46A 3B7OA 4ERCA 1YZ4A 1I9SA 5EHPA 1OHDA 3U96A 1C86A 2H03A 1Q6MA 3CWEA 2FH7A 5KABA 1G1FA 4IKCA 2MBCA 4R0TA 1OESA 3QCHA 2A3KA 4KI9A 5K22A 1ONYA 3EU0A 4Z6BA 1V3AA 1YTNA 1T48A 2GP0A 1YFOA 2F6FA 2F6TA 2PQ5A 4RI5A 3EZZA 2IMGA 4OHHA 5KA7A 2I75A 3V0HA 2CNFA 4RI4A 4H34A 2FJNA 1YGUA 1T49A 3PS5A 2GWOA 1C87A 5K9VA 1KAKA 1PA1A 1Q6TA 2QBQA 2HNPA 4GE6A 2R0BA 1XBOA 3QCBA 2BIJA 4D3RA 3F41A 1NL9A 3ZM0A 3ZV2A 4RDDA 2QDMA 2I5XA 3F9AA 1BZCA 3O4UA 1U24A 4QUMA 2PBNA 2Y96A 4D3PA 1PXHA 3ZMPA 2B07A 5KA4A 5KA8A 1RPMA 5KAAA 4JBCA 4TVVA 1OEMX 2A8BA 3EMUA 2CNEA 1YGRA 3MOZA 2CNIA 1EENA 3SR9A 1OEUA 2I6IA 4NNDA 5KA2A 2E0TA 3CM3A 2BGDA 1OEOX 1VHRA 1XXPA 3O3LA 1G7GA 2VEUA 1PA9A 2CNGA 1JF7A 1NNYA 3V0FA 2NTAA 4ICZA 2HNQA 4QBWA 3RO1A 3S3HA 1KAVA 4OHIA 4KYRA 3S3FA 2CMAA 5KA0A 1FPZA 2I6PA 2VEVA 3BLTA 1YN9A 3M4UA 2AHSA 5KA1A 3N0AA 3QCJA 4WTYA 5EHRA 4BJOA 1PH0A 1MKPA 3LJ8A 3QKQA 2HC1A 2J16B 4QUNA 4B04A 4HRFA 4QBEA 2F70A 2Y2FA 3MMJA 1GWZA 3AWGA 3GXGA 1BZHA 2OZ5A 4Y2EA 4GE2A 2CJZA 3ZM3A 2CM8A 2GJTA 2PI7A 5J8RA 2H04A 1ECVA 5K24A 2G59A 3OLRA 1X24A 1U26A 2NT7A 4JMJA 4PYHA 3O5XA 3BLUA 1RXDA 2G6ZA 2PA5A 1LQFA 4YAAA 2I1YA 2F6WA 5BZZA 4NX8A 1LARA 4GE5A 5LXQB 3QCEA 2P6XA 2I42A 2QCJA 1PTYA 2Q05A 3EB1A 1G1HA 2BV5A 3EAXA 2I4HA 1EEOA 4I8NA 3V0EA 4DGPA 4RH9A 2P4DA 5IBMA 3F81A 2SHPA 3I80A 3I7ZA 1ONZA 1L8GA 1G7FA 1U25A 2ZN7A 2CM7A 1M3GA 3O4SA 1J4XA 3GXHA 2F6ZA 1SUGA 1YTSA 1XRIA 4PVGA 2I6MA 3RZ2A 5KADA 2HVLA 1XM2A 1OEVA 2J16A 1Q6NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JMK A;  1PTT A;  3V0I A;  2QDP A;  4HJQ A;  2H4K A;  2AZR A;  3NME A;  3V0G A;  2H4V A;  3D1H A;  1AAX A;  3ZM2 A;  3O4T A;  2JJD A;  2QBS A;  4J51 A;  2FJM A;  1NZ7 A;  2HCM A;  4WU3 A;  1P15 A;  2VEX A;  1C83 A;  3QCM A;  4GS0 A;  1OET A;  4ZN5 A;  1WCH A;  2QDC A;  4NWG A;  2NT2 A;  2Q47 A;  5K25 A;  1ZCK A;  2B4P A;  3OMH A;  3QKP A;  2H02 A;  4DGX A;  2HC2 A;  3QCG A;  3QCF A;  5KA3 A;  1Q6P A;  1ZCL A;  2ESB A;  5K9W A;  1YWF A;  5K23 A;  2B4O A;  5KA9 A;  1PTU A;  1XXV A;  1C85 A;  2I3U A;  4AZ1 A;  2BGE A;  2H4G A;  4WOH A;  5BUG A;  3ZM1 A;  1Q6J A;  2DXP A;  2F6Y A;  1R6H A;  4NWF A;  4HJP A;  1WAX A;  4OHE A;  2I4G A;  1G4W R;  5MMZ B;  2QCT A;  1G4U S;  1ZC0 A;  4ZI4 A;  1D5R A;  4MBB A;  5I6V A;  2C7S A;  5BX1 A;  3D1O A;  2NLK A;  1LYV A;  3D44 A;  3V0J A;  3H2X A;  4ZRT A;  2CM2 A;  4GFV A;  2HB1 A;  2QEP A;  2I4E A;  3D9C A;  2OC3 A;  1OHC A;  4GFU A;  4S0G A;  1Q1M A;  2OOQ A;  1I9T A;  2PSZ A;  2J17 A;  2QBP A;  1YTW A;  2I6J A;  1Q6S A;  3QCI A;  4JNB A;  4OHL A;  2BZL A;  4RHG A;  2CM3 A;  2I3R A;  2CMC A;  1OHE A;  3D1Q A;  2NV5 A;  3QCC A;  4RH5 A;  2F71 A;  3S3E A;  5HDE A;  1NO6 A;  2HY3 A;  1QZ0 A;  2YDU A;  4QAP A;  2NZ6 A;  5GTJ A;  3D42 A;  4GRZ A;  1I57 A;  3AWE A;  2ZMM A;  3BRH A;  4NYH A;  5AWX A;  2OUD A;  3F9B A;  4GWF A;  5IBS A;  2B49 A;  3S4E A;  3QCL A;  1BZJ A;  1WRM A;  2B4S A;  2I6O A;  4Y14 A;  5KAC A;  2QBR A;  2VEY A;  4QAH A;  4R30 A;  1JLN A;  1GFY A;  3QCN A;  1G1G A;  1PTV A;  2HXP A;  2F46 A;  2CFV A;  3I36 A;  1T4J A;  4WU2 A;  1NWE A;  3S4O A;  3BM8 A;  1NWL A;  4YR8 B;  1A5Y A;  3F99 A;  3QCD A;  4H1O A;  4R0S A;  1L8K A;  3S3K A;  3RGQ A;  1FPR A;  3QCK A;  3A5J A;  1QXK A;  1C88 A;  4OHD A;  2M3V A;  3AWF A;  1PYN A;  3ZMQ A;  2B3O A;  1C84 A;  2CMB A;  5M43 A;  3RGO A;  4GRY A;  2WGP A;  1ZZW A;  2VEW A;  4RKK A;  2CNH A;  2RF6 A;  1YPT A;  2PT0 A;  5BZX A;  2F6V A;  2B4U A;  3SME A;  4KYQ A;  3MOW A;  4D3Q A;  3V0D A;  4BPC A;  1FQ1 A;  3A5K A;  2C46 A;  3B7O A;  4ERC A;  1YZ4 A;  1I9S A;  5EHP A;  1OHD A;  3U96 A;  1C86 A;  2H03 A;  1Q6M A;  3CWE A;  2FH7 A;  5KAB A;  1G1F A;  4IKC A;  2MBC A;  4R0T A;  1OES A;  3QCH A;  2A3K A;  4KI9 A;  5K22 A;  1ONY A;  3EU0 A;  4Z6B A;  1V3A A;  1YTN A;  1T48 A;  2GP0 A;  1YFO A;  2F6F A;  2F6T A;  2PQ5 A;  4RI5 A;  3EZZ A;  2IMG A;  4OHH A;  5KA7 A;  2I75 A;  3V0H A;  2CNF A;  4RI4 A;  4H34 A;  2FJN A;  1YGU A;  1T49 A;  3PS5 A;  2GWO A;  1C87 A;  5K9V A;  1KAK A;  1PA1 A;  1Q6T A;  2QBQ A;  2HNP A;  4GE6 A;  2R0B A;  1XBO A;  3QCB A;  2BIJ A;  4D3R A;  3F41 A;  1NL9 A;  3ZM0 A;  3ZV2 A;  4RDD A;  2QDM A;  2I5X A;  3F9A A;  1BZC A;  3O4U A;  1U24 A;  4QUM A;  2PBN A;  2Y96 A;  4D3P A;  1PXH A;  3ZMP A;  2B07 A;  5KA4 A;  5KA8 A;  1RPM A;  5KAA A;  4JBC A;  4TVV A;  1OEM X;  2A8B A;  3EMU A;  2CNE A;  1YGR A;  3MOZ A;  2CNI A;  1EEN A;  3SR9 A;  1OEU A;  2I6I A;  4NND A;  5KA2 A;  2E0T A;  3CM3 A;  2BGD A;  1OEO X;  1VHR A;  1XXP A;  3O3L A;  1G7G A;  2VEU A;  1PA9 A;  2CNG A;  1JF7 A;  1NNY A;  3V0F A;  2NTA A;  4ICZ A;  2HNQ A;  4QBW A;  3RO1 A;  3S3H A;  1KAV A;  4OHI A;  4KYR A;  3S3F A;  2CMA A;  5KA0 A;  1FPZ A;  2I6P A;  2VEV A;  3BLT A;  1YN9 A;  3M4U A;  2AHS A;  5KA1 A;  3N0A A;  3QCJ A;  4WTY A;  5EHR A;  4BJO A;  1PH0 A;  1MKP A;  3LJ8 A;  3QKQ A;  2HC1 A;  2J16 B;  4QUN A;  4B04 A;  4HRF A;  4QBE A;  2F70 A;  2Y2F A;  3MMJ A;  1GWZ A;  3AWG A;  3GXG A;  1BZH A;  2OZ5 A;  4Y2E A;  4GE2 A;  2CJZ A;  3ZM3 A;  2CM8 A;  2GJT A;  2PI7 A;  5J8R A;  2H04 A;  1ECV A;  5K24 A;  2G59 A;  3OLR A;  1X24 A;  1U26 A;  2NT7 A;  4JMJ A;  4PYH A;  3O5X A;  3BLU A;  1RXD A;  2G6Z A;  2PA5 A;  1LQF A;  4YAA A;  2I1Y A;  2F6W A;  5BZZ A;  4NX8 A;  1LAR A;  4GE5 A;  5LXQ B;  3QCE A;  2P6X A;  2I42 A;  2QCJ A;  1PTY A;  2Q05 A;  3EB1 A;  1G1H A;  2BV5 A;  3EAX A;  2I4H A;  1EEO A;  4I8N A;  3V0E A;  4DGP A;  4RH9 A;  2P4D A;  5IBM A;  3F81 A;  2SHP A;  3I80 A;  3I7Z A;  1ONZ A;  1L8G A;  1G7F A;  1U25 A;  2ZN7 A;  2CM7 A;  1M3G A;  3O4S A;  1J4X A;  3GXH A;  2F6Z A;  1SUG A;  1YTS A;  1XRI A;  4PVG A;  2I6M A;  3RZ2 A;  5KAD A;  2HVL A;  1XM2 A;  1OEV A;  2J16 A;  1Q6N A; 
#chains in the Genus database with same CATH topology
 4JMK A;  1PTT A;  3V0I A;  2QDP A;  4HJQ A;  2H4K A;  2AZR A;  3NME A;  3V0G A;  2H4V A;  3D1H A;  1AAX A;  3ZM2 A;  3O4T A;  2JJD A;  2QBS A;  2F00 A;  4J51 A;  2FJM A;  1NZ7 A;  2HCM A;  4WU3 A;  1P15 A;  2VEX A;  1C83 A;  2UAG A;  3QCM A;  2XJA A;  2Y67 A;  4GS0 A;  1OET A;  4CVK A;  4ZN5 A;  1WCH A;  2QDC A;  4NWG A;  1UAG A;  2NT2 A;  2Q47 A;  2Y1O A;  5K25 A;  1ZCK A;  2B4P A;  3OMH A;  3QKP A;  2H02 A;  4DGX A;  2HC2 A;  3QCG A;  3QCF A;  5KA3 A;  1Q6P A;  1ZCL A;  2ESB A;  5K9W A;  1YWF A;  1P3D A;  5K23 A;  2B4O A;  5KA9 A;  1W78 A;  1PTU A;  1XXV A;  1C85 A;  2I3U A;  4AZ1 A;  2BGE A;  2H4G A;  4WOH A;  5BUG A;  3ZM1 A;  1Q6J A;  2DXP A;  2F6Y A;  1R6H A;  4NWF A;  4HJP A;  1WAX A;  4OHE A;  4BUB A;  2GC5 A;  2I4G A;  2WTZ A;  1G4W R;  5MMZ B;  2QCT A;  1G4U S;  1ZC0 A;  4ZI4 A;  1D5R A;  4MBB A;  5A5F A;  5I6V A;  2C7S A;  4C13 A;  5BX1 A;  3D1O A;  2NLK A;  1LYV A;  3D44 A;  1P31 A;  3V0J A;  3H2X A;  5A5E A;  2AM2 A;  4ZRT A;  2CM2 A;  3NRS A;  3ZM5 A;  4GFV A;  2HB1 A;  2QEP A;  1GQQ A;  2I4E A;  2Y66 A;  3D9C A;  2OC3 A;  1OHC A;  4GFU A;  4S0G A;  1Q1M A;  2OOQ A;  1I9T A;  2PSZ A;  2J17 A;  2QBP A;  1YTW A;  2I6J A;  1Q6S A;  3QCI A;  4JNB A;  1E8C A;  2BZL A;  4OHL A;  4RHG A;  2CM3 A;  2I3R A;  2CMC A;  3HN7 A;  1OHE A;  3D1Q A;  2NV5 A;  3QCC A;  4RH5 A;  2F71 A;  3S3E A;  5HDE A;  1NO6 A;  2HY3 A;  1QZ0 A;  2YDU A;  4QAP A;  2NZ6 A;  5GTJ A;  2JFH A;  3D42 A;  4GRZ A;  1I57 A;  3AWE A;  2ZMM A;  3BRH A;  4NYH A;  5AWX A;  2OUD A;  1J6U A;  3F9B A;  4GWF A;  5IBS A;  2B49 A;  3S4E A;  3QCL A;  1E0D A;  1BZJ A;  1WRM A;  2B4S A;  2I6O A;  4Y14 A;  3MVN A;  5KAC A;  2QBR A;  2VEY A;  4QAH A;  4R30 A;  1JLN A;  2X5O A;  1GFY A;  3QCN A;  2JFF A;  1GQY A;  1G1G A;  2GC6 A;  1PTV A;  2HXP A;  2UUP A;  2F46 A;  4HV4 A;  2CFV A;  3I36 A;  1T4J A;  4WU2 A;  2UUO A;  4QF5 A;  1NWE A;  3S4O A;  3BM8 A;  1NWL A;  4YR8 B;  1A5Y A;  3ZM6 A;  3F99 A;  3QCD A;  4H1O A;  4R0S A;  1L8K A;  3S3K A;  3RGQ A;  1FPR A;  4CVL A;  4UAG A;  3QCK A;  3A5J A;  1QXK A;  1C88 A;  4OHD A;  2M3V A;  3AWF A;  1PYN A;  3ZMQ A;  2B3O A;  1C84 A;  2CMB A;  5M43 A;  3RGO A;  4GRY A;  2WGP A;  1ZZW A;  2VEW A;  4RKK A;  2CNH A;  2RF6 A;  2VOR A;  1YPT A;  2PT0 A;  2VTE A;  5BZX A;  2F6V A;  3UAG A;  2B4U A;  3SME A;  4KYQ A;  2VTD A;  3MOW A;  4D3Q A;  3V0D A;  4BPC A;  4QDI A;  1FQ1 A;  3A5K A;  2C46 A;  3B7O A;  4ERC A;  1YZ4 A;  4BUC A;  1I9S A;  5EHP A;  1OHD A;  3U96 A;  1JBW A;  2XPC A;  3ZL8 A;  1C86 A;  2H03 A;  1Q6M A;  3CWE A;  2FH7 A;  5KAB A;  1G1F A;  4IKC A;  2MBC A;  4R0T A;  1OES A;  3QCH A;  2A3K A;  4KI9 A;  5K22 A;  1ONY A;  3EU0 A;  4Z6B A;  1V3A A;  1YTN A;  1T48 A;  2GP0 A;  1YFO A;  2F6F A;  2AM1 A;  2F6T A;  2PQ5 A;  2Y68 A;  4RI5 A;  3EZZ A;  2IMG A;  4OHH A;  5KA7 A;  2I75 A;  3V0H A;  2CNF A;  4RI4 A;  4H34 A;  2FJN A;  1YGU A;  1T49 A;  3PS5 A;  2GWO A;  1C87 A;  1EEH A;  5K9V A;  1KAK A;  1PA1 A;  1Q6T A;  2QBQ A;  2HNP A;  4GE6 A;  2R0B A;  1XBO A;  3QCB A;  2BIJ A;  4D3R A;  3F41 A;  1NL9 A;  3ZM0 A;  3ZV2 A;  4RDD A;  2QDM A;  2I5X A;  3F9A A;  1BZC A;  3O4U A;  1U24 A;  4QUM A;  2PBN A;  2Y96 A;  4D3P A;  1PXH A;  3ZMP A;  2B07 A;  5KA4 A;  5KA8 A;  1RPM A;  5KAA A;  4JBC A;  4TVV A;  1OEM X;  2A8B A;  3EMU A;  2CNE A;  1YGR A;  3MOZ A;  2CNI A;  1EEN A;  1W7K A;  3SR9 A;  1O5Z A;  1OEU A;  2I6I A;  4NND A;  5KA2 A;  2E0T A;  3CM3 A;  2BGD A;  1OEO X;  1VHR A;  1XXP A;  3O3L A;  1G7G A;  2VEU A;  4C12 A;  1PA9 A;  2CNG A;  1JF7 A;  3N2A A;  1NNY A;  3V0F A;  2NTA A;  4ICZ A;  2HNQ A;  4QBW A;  3RO1 A;  3S3H A;  1KAV A;  4OHI A;  1JBV A;  4KYR A;  3S3F A;  2CMA A;  5KA0 A;  1FPZ A;  2I6P A;  4ZIY A;  2VEV A;  3BLT A;  1YN9 A;  3M4U A;  2AHS A;  5KA1 A;  3N0A A;  3QCJ A;  4WTY A;  5EHR A;  4BJO A;  1PH0 A;  1MKP A;  3LJ8 A;  3QKQ A;  2HC1 A;  2J16 B;  4QUN A;  4B04 A;  4HRF A;  4QBE A;  2F70 A;  2Y2F A;  3MMJ A;  2JFG A;  1GWZ A;  3AWG A;  2WJP A;  3GXG A;  1BZH A;  2OZ5 A;  4Y2E A;  4GE2 A;  2CJZ A;  3LK7 A;  3ZM3 A;  2CM8 A;  2GJT A;  2PI7 A;  5J8R A;  2H04 A;  1ECV A;  5K24 A;  2G59 A;  3OLR A;  1X24 A;  4CVM A;  1U26 A;  2NT7 A;  4JMJ A;  4PYH A;  3O5X A;  2VOS A;  3BLU A;  1RXD A;  2G6Z A;  2PA5 A;  1LQF A;  4YAA A;  2I1Y A;  2F6W A;  5BZZ A;  4NX8 A;  1LAR A;  4GE5 A;  5LXQ B;  3QCE A;  2P6X A;  2I42 A;  2QCJ A;  1PTY A;  2Q05 A;  3EB1 A;  2GCA A;  1G1H A;  2BV5 A;  3PYZ A;  3EAX A;  2I4H A;  2GCB A;  1EEO A;  4I8N A;  3V0E A;  4DGP A;  4RH9 A;  2P4D A;  5IBM A;  1GG4 A;  3F81 A;  3QCZ A;  2SHP A;  3I80 A;  3I7Z A;  1ONZ A;  1L8G A;  1G7F A;  1U25 A;  2ZN7 A;  2CM7 A;  1M3G A;  3O4S A;  1J4X A;  1FGS A;  3GXH A;  2F6Z A;  1SUG A;  1YTS A;  1XRI A;  4PVG A;  2I6M A;  3RZ2 A;  5KAD A;  2HVL A;  1XM2 A;  1OEV A;  2J16 A;  1Q6N A; 
#chains in the Genus database with same CATH homology
 4JMK A;  1PTT A;  3V0I A;  2QDP A;  4HJQ A;  2H4K A;  2AZR A;  3NME A;  3V0G A;  2H4V A;  3D1H A;  1AAX A;  3ZM2 A;  3O4T A;  2JJD A;  2QBS A;  4J51 A;  2FJM A;  1NZ7 A;  2HCM A;  4WU3 A;  1P15 A;  2VEX A;  1C83 A;  3QCM A;  4GS0 A;  1OET A;  4ZN5 A;  1WCH A;  2QDC A;  4NWG A;  2NT2 A;  2Q47 A;  5K25 A;  1ZCK A;  2B4P A;  3OMH A;  3QKP A;  2H02 A;  4DGX A;  2HC2 A;  3QCG A;  3QCF A;  5KA3 A;  1Q6P A;  1ZCL A;  2ESB A;  5K9W A;  1YWF A;  5K23 A;  2B4O A;  5KA9 A;  1PTU A;  1XXV A;  1C85 A;  2I3U A;  4AZ1 A;  2BGE A;  2H4G A;  4WOH A;  5BUG A;  3ZM1 A;  1Q6J A;  2DXP A;  2F6Y A;  1R6H A;  4NWF A;  4HJP A;  1WAX A;  4OHE A;  2I4G A;  1G4W R;  5MMZ B;  2QCT A;  1G4U S;  1ZC0 A;  4ZI4 A;  1D5R A;  4MBB A;  5I6V A;  2C7S A;  5BX1 A;  3D1O A;  2NLK A;  1LYV A;  3D44 A;  3V0J A;  3H2X A;  4ZRT A;  2CM2 A;  4GFV A;  2HB1 A;  2QEP A;  2I4E A;  3D9C A;  2OC3 A;  1OHC A;  4GFU A;  4S0G A;  1Q1M A;  2OOQ A;  1I9T A;  2PSZ A;  2J17 A;  2QBP A;  1YTW A;  2I6J A;  1Q6S A;  3QCI A;  4JNB A;  4OHL A;  2BZL A;  4RHG A;  2CM3 A;  2I3R A;  2CMC A;  1OHE A;  3D1Q A;  2NV5 A;  3QCC A;  4RH5 A;  2F71 A;  3S3E A;  5HDE A;  1NO6 A;  2HY3 A;  1QZ0 A;  2YDU A;  4QAP A;  2NZ6 A;  5GTJ A;  3D42 A;  4GRZ A;  1I57 A;  3AWE A;  2ZMM A;  3BRH A;  4NYH A;  5AWX A;  2OUD A;  3F9B A;  4GWF A;  5IBS A;  2B49 A;  3S4E A;  3QCL A;  1BZJ A;  1WRM A;  2B4S A;  2I6O A;  4Y14 A;  5KAC A;  2QBR A;  2VEY A;  4QAH A;  4R30 A;  1JLN A;  1GFY A;  3QCN A;  1G1G A;  1PTV A;  2HXP A;  2F46 A;  2CFV A;  3I36 A;  1T4J A;  4WU2 A;  1NWE A;  3S4O A;  3BM8 A;  1NWL A;  4YR8 B;  1A5Y A;  3F99 A;  3QCD A;  4H1O A;  4R0S A;  1L8K A;  3S3K A;  3RGQ A;  1FPR A;  3QCK A;  3A5J A;  1QXK A;  1C88 A;  4OHD A;  2M3V A;  3AWF A;  1PYN A;  3ZMQ A;  2B3O A;  1C84 A;  2CMB A;  5M43 A;  3RGO A;  4GRY A;  2WGP A;  1ZZW A;  2VEW A;  4RKK A;  2CNH A;  2RF6 A;  1YPT A;  2PT0 A;  5BZX A;  2F6V A;  2B4U A;  3SME A;  4KYQ A;  3MOW A;  4D3Q A;  3V0D A;  4BPC A;  1FQ1 A;  3A5K A;  2C46 A;  3B7O A;  4ERC A;  1YZ4 A;  1I9S A;  5EHP A;  1OHD A;  3U96 A;  1C86 A;  2H03 A;  1Q6M A;  3CWE A;  2FH7 A;  5KAB A;  1G1F A;  4IKC A;  2MBC A;  4R0T A;  1OES A;  3QCH A;  2A3K A;  4KI9 A;  5K22 A;  1ONY A;  3EU0 A;  4Z6B A;  1V3A A;  1YTN A;  1T48 A;  2GP0 A;  1YFO A;  2F6F A;  2F6T A;  2PQ5 A;  4RI5 A;  3EZZ A;  2IMG A;  4OHH A;  5KA7 A;  2I75 A;  3V0H A;  2CNF A;  4RI4 A;  4H34 A;  2FJN A;  1YGU A;  1T49 A;  3PS5 A;  2GWO A;  1C87 A;  5K9V A;  1KAK A;  1PA1 A;  1Q6T A;  2QBQ A;  2HNP A;  4GE6 A;  2R0B A;  1XBO A;  3QCB A;  2BIJ A;  4D3R A;  3F41 A;  1NL9 A;  3ZM0 A;  3ZV2 A;  4RDD A;  2QDM A;  2I5X A;  3F9A A;  1BZC A;  3O4U A;  1U24 A;  4QUM A;  2PBN A;  2Y96 A;  4D3P A;  1PXH A;  3ZMP A;  2B07 A;  5KA4 A;  5KA8 A;  1RPM A;  5KAA A;  4JBC A;  4TVV A;  1OEM X;  2A8B A;  3EMU A;  2CNE A;  1YGR A;  3MOZ A;  2CNI A;  1EEN A;  3SR9 A;  1OEU A;  2I6I A;  4NND A;  5KA2 A;  2E0T A;  3CM3 A;  2BGD A;  1OEO X;  1VHR A;  1XXP A;  3O3L A;  1G7G A;  2VEU A;  1PA9 A;  2CNG A;  1JF7 A;  1NNY A;  3V0F A;  2NTA A;  4ICZ A;  2HNQ A;  4QBW A;  3RO1 A;  3S3H A;  1KAV A;  4OHI A;  4KYR A;  3S3F A;  2CMA A;  5KA0 A;  1FPZ A;  2I6P A;  2VEV A;  3BLT A;  1YN9 A;  3M4U A;  2AHS A;  5KA1 A;  3N0A A;  3QCJ A;  4WTY A;  5EHR A;  4BJO A;  1PH0 A;  1MKP A;  3LJ8 A;  3QKQ A;  2HC1 A;  2J16 B;  4QUN A;  4B04 A;  4HRF A;  4QBE A;  2F70 A;  2Y2F A;  3MMJ A;  1GWZ A;  3AWG A;  3GXG A;  1BZH A;  2OZ5 A;  4Y2E A;  4GE2 A;  2CJZ A;  3ZM3 A;  2CM8 A;  2GJT A;  2PI7 A;  5J8R A;  2H04 A;  1ECV A;  5K24 A;  2G59 A;  3OLR A;  1X24 A;  1U26 A;  2NT7 A;  4JMJ A;  4PYH A;  3O5X A;  3BLU A;  1RXD A;  2G6Z A;  2PA5 A;  1LQF A;  4YAA A;  2I1Y A;  2F6W A;  5BZZ A;  4NX8 A;  1LAR A;  4GE5 A;  5LXQ B;  3QCE A;  2P6X A;  2I42 A;  2QCJ A;  1PTY A;  2Q05 A;  3EB1 A;  1G1H A;  2BV5 A;  3EAX A;  2I4H A;  1EEO A;  4I8N A;  3V0E A;  4DGP A;  4RH9 A;  2P4D A;  5IBM A;  3F81 A;  2SHP A;  3I80 A;  3I7Z A;  1ONZ A;  1L8G A;  1G7F A;  1U25 A;  2ZN7 A;  2CM7 A;  1M3G A;  3O4S A;  1J4X A;  3GXH A;  2F6Z A;  1SUG A;  1YTS A;  1XRI A;  4PVG A;  2I6M A;  3RZ2 A;  5KAD A;  2HVL A;  1XM2 A;  1OEV A;  2J16 A;  1Q6N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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