4HKCA

14-3-3-zeta in complex with s1011 phosphorylated integrin alpha-4 peptide
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
229
structure length
229
Chain Sequence
DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of 14-3-3-zeta Interactions with integrin tails
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords 14-3-3 protein zeta/delta
total genus 101
structure length 229
sequence length 229
ec nomenclature
pdb deposition date 2012-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 4hkcA00
2NPMA 1IB1A 4F7RA 3M51A 4E2EA 4FR3A 3P1PA 3IQJA 3P1OA 4DHUA 4DHQA 4O46A 2C23A 2BQ0A 4DAUA 4GNTA 3P1QA 4Y32A 4FJ3A 2C63A 4HKCA 2C1NA 3O8IA 3EFZA 4DX0A 2BTPA 3M50A 3T0LA 1O9CA 4DHNA 3MHRA 4JDDA 4J6SA 4JC3A 1QJBA 3SMKA 2WH0A 3CU8A 3IQVA 4FL5A 4DHOA 4DATA 4Y5IA 1YZ5A 3LW1A 1A4OA 4N84A 4N7GA 3SP5A 2C1JA 3SMLA 3P1NA 2V7DA 4BG6A 1A37A 3SMMA 4IHLA 4WRQA 3NKXA 5HF3A 4N7YA 4DHSA 2O98A 5BTVA 3AXYC 5D3EA 5LVZA 2C74A 5J31A 4DNKA 1QJAA 5LU2A 5LU1A 2O8PA 3RDHA 4ZQ0A 3UBWA 1A38A 4DHMA 2B05A 3IQUA 4DHRA 4ZDRA 1O9EA 3SMOA 5D3FA 5F74A 5BY9A 5EWZA 3SPRA 3U9XA 3SMNA 2O02A 3UZDA 4DHTA 4IEAA 1YWTA 3UALA 3P1SA 2BR9A 3P1RA 5D2DA 5LHOA 3E6YA 5IQPA 5LX2A 5EXAA 3T0MA 4Y3BA 1O9DA 3UX0A 4DHPA 4QLIA 1O9FA
chains in the Genus database with same CATH superfamily
2NPMA 1IB1A 4F7RA 3M51A 4E2EA 4FR3A 3P1PA 3IQJA 4ARYA 3P1OA 4DHUA 1DLCA 4DHQA 4O46A 2C23A 2BQ0A 4DAUA 3CQGA 4GNTA 3P1QA 4Y32A 4FJ3A 2C63A 1W99A 4HKCA 2C1NA 3O8IA 3EFZA 4D8MA 4DX0A 2BTPA 3M50A 3T0LA 1O9CA 4DHNA 3MHRA 4QX0A 2C9KA 4JDDA 4J6SA 4JC3A 1CIYA 1QJBA 3SMKA 2WH0A 3CU8A 3IQVA 4FL5A 4DHOA 4DATA 4Y5IA 1YZ5A 3LW1A 1A4OA 4QX1A 4N84A 4N7GA 3SP5A 2C1JA 3SMLA 3P1NA 2V7DA 4BG6A 1A37A 3SMMA 4IHLA 3EB7A 4WRQA 3NKXA 5HF3A 4N7YA 4DHSA 2O98A 5BTVA 3AXYC 5D3EA 4MOAA 5LVZA 2C74A 5J31A 4DNKA 1QJAA 5LU2A 5LU1A 4ARXA 1S2XA 2O8PA 3RDHA 4ZQ0A 3UBWA 1A38A 4DHMA 2B05A 3IQUA 1URJA 4DHRA 1JI6A 3CQCA 4ZDRA 1O9EA 3SMOA 5D3FA 5F74A 5BY9A 5EWZA 1I5PA 3SPRA 3U9XA 3SMNA 2O02A 3X0UA 3UZDA 4DHTA 4IEAA 4W8JA 1YWTA 3UALA 3I4RA 3P1SA 2BR9A 3P1RA 5D2DA 5LHOA 3E6YA 5IQPA 5LX2A 5EXAA 3T0MA 4Y3BA 1O9DA 3UX0A 4DHPA 3ZHEB 4QX2A 4QLIA 1O9FA 4QX3A
chains in the Genus database with same CATH topology
2NPMA 1IB1A 4F7RA 3M51A 4E2EA 4FR3A 3P1PA 3IQJA 3P1OA 4DHUA 4DHQA 4O46A 2C23A 2BQ0A 4DAUA 4GNTA 3P1QA 4Y32A 4FJ3A 2C63A 4HKCA 2C1NA 3O8IA 3EFZA 4DX0A 2BTPA 3M50A 3T0LA 1O9CA 4DHNA 3MHRA 4JDDA 4J6SA 4JC3A 1QJBA 3SMKA 2WH0A 3CU8A 3IQVA 4FL5A 4DHOA 4DATA 4Y5IA 1YZ5A 3LW1A 1A4OA 4N84A 4N7GA 3SP5A 2C1JA 3SMLA 3P1NA 2V7DA 4BG6A 1A37A 3SMMA 4IHLA 4WRQA 3NKXA 5HF3A 4N7YA 4DHSA 2O98A 5BTVA 3AXYC 5D3EA 5LVZA 2C74A 5J31A 4DNKA 1QJAA 5LU2A 5LU1A 2O8PA 3RDHA 4ZQ0A 3UBWA 1A38A 4DHMA 2B05A 3IQUA 4DHRA 4ZDRA 1O9EA 3SMOA 5D3FA 5F74A 5BY9A 5EWZA 3SPRA 3U9XA 3SMNA 2O02A 3UZDA 4DHTA 4IEAA 1YWTA 3UALA 3P1SA 2BR9A 3P1RA 5D2DA 5LHOA 3E6YA 5IQPA 5LX2A 5EXAA 3T0MA 4Y3BA 1O9DA 3UX0A 4DHPA 4QLIA 1O9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NPM A;  1IB1 A;  4F7R A;  3M51 A;  4E2E A;  4FR3 A;  3P1P A;  3IQJ A;  3P1O A;  4DHU A;  4DHQ A;  4O46 A;  2C23 A;  2BQ0 A;  4DAU A;  4GNT A;  3P1Q A;  4Y32 A;  4FJ3 A;  2C63 A;  4HKC A;  2C1N A;  3O8I A;  3EFZ A;  4DX0 A;  2BTP A;  3M50 A;  3T0L A;  1O9C A;  4DHN A;  3MHR A;  4JDD A;  4J6S A;  4JC3 A;  1QJB A;  3SMK A;  2WH0 A;  3CU8 A;  3IQV A;  4FL5 A;  4DHO A;  4DAT A;  4Y5I A;  1YZ5 A;  3LW1 A;  1A4O A;  4N84 A;  4N7G A;  3SP5 A;  2C1J A;  3SML A;  3P1N A;  2V7D A;  4BG6 A;  1A37 A;  3SMM A;  4IHL A;  4WRQ A;  3NKX A;  5HF3 A;  4N7Y A;  4DHS A;  2O98 A;  5BTV A;  3AXY C;  5D3E A;  5LVZ A;  2C74 A;  5J31 A;  4DNK A;  1QJA A;  5LU2 A;  5LU1 A;  2O8P A;  3RDH A;  4ZQ0 A;  3UBW A;  1A38 A;  4DHM A;  2B05 A;  3IQU A;  4DHR A;  4ZDR A;  1O9E A;  3SMO A;  5D3F A;  5F74 A;  5BY9 A;  5EWZ A;  3SPR A;  3U9X A;  3SMN A;  2O02 A;  3UZD A;  4DHT A;  4IEA A;  1YWT A;  3UAL A;  3P1S A;  2BR9 A;  3P1R A;  5D2D A;  5LHO A;  3E6Y A;  5IQP A;  5LX2 A;  5EXA A;  3T0M A;  4Y3B A;  1O9D A;  3UX0 A;  4DHP A;  4QLI A;  1O9F A; 
#chains in the Genus database with same CATH topology
 2NPM A;  1IB1 A;  4F7R A;  3M51 A;  4E2E A;  4FR3 A;  3P1P A;  3IQJ A;  4ARY A;  3P1O A;  4DHU A;  1DLC A;  4DHQ A;  4O46 A;  2C23 A;  2BQ0 A;  4DAU A;  3CQG A;  4GNT A;  3P1Q A;  4Y32 A;  4FJ3 A;  2C63 A;  1W99 A;  4HKC A;  2C1N A;  3O8I A;  3EFZ A;  4D8M A;  4DX0 A;  2BTP A;  3M50 A;  3T0L A;  1O9C A;  4DHN A;  3MHR A;  4QX0 A;  2C9K A;  4JDD A;  4J6S A;  4JC3 A;  1CIY A;  1QJB A;  3SMK A;  2WH0 A;  3CU8 A;  3IQV A;  4FL5 A;  4DHO A;  4DAT A;  4Y5I A;  1YZ5 A;  3LW1 A;  1A4O A;  4QX1 A;  4N84 A;  4N7G A;  3SP5 A;  2C1J A;  3SML A;  3P1N A;  2V7D A;  4BG6 A;  1A37 A;  3SMM A;  4IHL A;  3EB7 A;  4WRQ A;  3NKX A;  5HF3 A;  4N7Y A;  4DHS A;  2O98 A;  5BTV A;  3AXY C;  5D3E A;  4MOA A;  5LVZ A;  2C74 A;  5J31 A;  4DNK A;  1QJA A;  5LU2 A;  5LU1 A;  4ARX A;  1S2X A;  2O8P A;  3RDH A;  4ZQ0 A;  3UBW A;  1A38 A;  4DHM A;  2B05 A;  3IQU A;  1URJ A;  4DHR A;  1JI6 A;  3CQC A;  4ZDR A;  1O9E A;  3SMO A;  5D3F A;  5F74 A;  5BY9 A;  5EWZ A;  1I5P A;  3SPR A;  3U9X A;  3SMN A;  2O02 A;  3X0U A;  3UZD A;  4DHT A;  4IEA A;  4W8J A;  1YWT A;  3UAL A;  3I4R A;  3P1S A;  2BR9 A;  3P1R A;  5D2D A;  5LHO A;  3E6Y A;  5IQP A;  5LX2 A;  5EXA A;  3T0M A;  4Y3B A;  1O9D A;  3UX0 A;  4DHP A;  3ZHE B;  4QX2 A;  4QLI A;  1O9F A;  4QX3 A; 
#chains in the Genus database with same CATH homology
 2NPM A;  1IB1 A;  4F7R A;  3M51 A;  4E2E A;  4FR3 A;  3P1P A;  3IQJ A;  3P1O A;  4DHU A;  4DHQ A;  4O46 A;  2C23 A;  2BQ0 A;  4DAU A;  4GNT A;  3P1Q A;  4Y32 A;  4FJ3 A;  2C63 A;  4HKC A;  2C1N A;  3O8I A;  3EFZ A;  4DX0 A;  2BTP A;  3M50 A;  3T0L A;  1O9C A;  4DHN A;  3MHR A;  4JDD A;  4J6S A;  4JC3 A;  1QJB A;  3SMK A;  2WH0 A;  3CU8 A;  3IQV A;  4FL5 A;  4DHO A;  4DAT A;  4Y5I A;  1YZ5 A;  3LW1 A;  1A4O A;  4N84 A;  4N7G A;  3SP5 A;  2C1J A;  3SML A;  3P1N A;  2V7D A;  4BG6 A;  1A37 A;  3SMM A;  4IHL A;  4WRQ A;  3NKX A;  5HF3 A;  4N7Y A;  4DHS A;  2O98 A;  5BTV A;  3AXY C;  5D3E A;  5LVZ A;  2C74 A;  5J31 A;  4DNK A;  1QJA A;  5LU2 A;  5LU1 A;  2O8P A;  3RDH A;  4ZQ0 A;  3UBW A;  1A38 A;  4DHM A;  2B05 A;  3IQU A;  4DHR A;  4ZDR A;  1O9E A;  3SMO A;  5D3F A;  5F74 A;  5BY9 A;  5EWZ A;  3SPR A;  3U9X A;  3SMN A;  2O02 A;  3UZD A;  4DHT A;  4IEA A;  1YWT A;  3UAL A;  3P1S A;  2BR9 A;  3P1R A;  5D2D A;  5LHO A;  3E6Y A;  5IQP A;  5LX2 A;  5EXA A;  3T0M A;  4Y3B A;  1O9D A;  3UX0 A;  4DHP A;  4QLI A;  1O9F A; 
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