4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Tankyrase-2
publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
4L31C 4UI8C 4UI3C 4UVPB 5C5PC 4HKNC 4KZLC 5C5RC 5FPFC 4HLKC 4KZQC 4L32C 5ADQB 4HLGC 4L34C 5C5QC 4L0SC 4UI6C 4KZUC 5ADSB 4UI4C 4HLHC 4HLFC 4HL5C 4UI5C 5ADRB 4HKKB 4L0TC 4L10C 4HKIC 4L09C 5ADTB 4L0BC 4HLMC 4UI7C 4L33C 4L0IC 4L2KC 4HMHC 4L0VC 4L2FC 4L2GC
chains in the Genus database with same CATH superfamily
3HS2A 4L31C 4UI3C 4UI8C 4UVPB 3K33B 5C5PC 3HJ6A 3D55A 3KH2E 4HKNC 4KZLC 3OEIE 3HRYA 5C5RC 4ZM0A 5FPFC 4HLKC 2ODKA 3OEIA 4KZQC 4L32C 4ZLXA 5ADQB 3G5OA 4HLGC 4L34C 5C5QC 4L0SC 4UI6C 4KZUC 5ADSB 4UI4C 4HLHC 2A6QA 4HL5C 4HLFC 4UI5C 3CTOA 3K6QA 5ADRB 4HKKB 4L0TC 4L10C 4HKIC 4L09C 5ADTB 4ZM2A 4L0BC 4HLMC 4UI7C 4L33C 2ZIXB 4L0IC 4L2KC 4HMHC 4L0VC 4L2FC 4L2GC
chains in the Genus database with same CATH topology
4L31C 4UI8C 4UI3C 4UVPB 5C5PC 3HJ6A 4HKNC 4KZLC 5C5RC 5FPFC 4HLKC 4KZQC 4L32C 5ADQB 4HLGC 4L34C 5C5QC 4L0SC 4UI6C 4KZUC 5ADSB 4UI4C 4HLHC 4HLFC 4HL5C 4UI5C 5ADRB 4HKKB 4L0TC 4L10C 4HKIC 4L09C 5ADTB 4L0BC 4HLMC 4UI7C 4L33C 2ZIXB 4L0IC 4L2KC 4HMHC 4L0VC 4L2FC 4L2GC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L31 C;  4UI8 C;  4UI3 C;  4UVP B;  5C5P C;  4HKN C;  4KZL C;  5C5R C;  5FPF C;  4HLK C;  4KZQ C;  4L32 C;  5ADQ B;  4HLG C;  4L34 C;  5C5Q C;  4L0S C;  4UI6 C;  4KZU C;  5ADS B;  4UI4 C;  4HLH C;  4HLF C;  4HL5 C;  4UI5 C;  5ADR B;  4HKK B;  4L0T C;  4L10 C;  4HKI C;  4L09 C;  5ADT B;  4L0B C;  4HLM C;  4UI7 C;  4L33 C;  4L0I C;  4L2K C;  4HMH C;  4L0V C;  4L2F C;  4L2G C; 
#chains in the Genus database with same CATH topology
 3HS2 A;  4L31 C;  4UI3 C;  4UI8 C;  4UVP B;  3K33 B;  5C5P C;  3HJ6 A;  3D55 A;  3KH2 E;  4HKN C;  4KZL C;  3OEI E;  3HRY A;  5C5R C;  4ZM0 A;  5FPF C;  4HLK C;  2ODK A;  3OEI A;  4KZQ C;  4L32 C;  4ZLX A;  5ADQ B;  3G5O A;  4HLG C;  4L34 C;  5C5Q C;  4L0S C;  4UI6 C;  4KZU C;  5ADS B;  4UI4 C;  4HLH C;  2A6Q A;  4HL5 C;  4HLF C;  4UI5 C;  3CTO A;  3K6Q A;  5ADR B;  4HKK B;  4L0T C;  4L10 C;  4HKI C;  4L09 C;  5ADT B;  4ZM2 A;  4L0B C;  4HLM C;  4UI7 C;  4L33 C;  2ZIX B;  4L0I C;  4L2K C;  4HMH C;  4L0V C;  4L2F C;  4L2G C; 
#chains in the Genus database with same CATH homology
 4L31 C;  4UI8 C;  4UI3 C;  4UVP B;  5C5P C;  3HJ6 A;  4HKN C;  4KZL C;  5C5R C;  5FPF C;  4HLK C;  4KZQ C;  4L32 C;  5ADQ B;  4HLG C;  4L34 C;  5C5Q C;  4L0S C;  4UI6 C;  4KZU C;  5ADS B;  4UI4 C;  4HLH C;  4HLF C;  4HL5 C;  4UI5 C;  5ADR B;  4HKK B;  4L0T C;  4L10 C;  4HKI C;  4L09 C;  5ADT B;  4L0B C;  4HLM C;  4UI7 C;  4L33 C;  2ZIX B;  4L0I C;  4L2K C;  4HMH C;  4L0V C;  4L2F C;  4L2G C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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