4HL5C

Complex structure of human tankyrase 2 with 7-hydroxy -4'-methoxyflavone
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Tankyrase-2
publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hl5C00
4UI6C 4L09C 4HMHC 4KZUC 4L0VC 4UI7C 4HL5C 5ADRB 4L0BC 4L2FC 4UI5C 4KZQC 4HKNC 4L0SC 5ADTB 5ADSB 4UVPB 4L2GC 4HKIC 4UI3C 4UI4C 5C5RC 5C5PC 4KZLC 4L32C 4L10C 4L33C 4L0TC 4L2KC 5FPFC 4HLKC 5C5QC 4HKKB 4HLMC 4HLHC 4HLFC 4L31C 5ADQB 4L34C 4HLGC 4L0IC 4UI8C
chains in the Genus database with same CATH superfamily
3OEIE 4UI6C 4L09C 4HMHC 4KZUC 3D55A 4L0VC 4HL5C 4UI7C 5ADRB 4L0BC 4L2FC 3K6QA 4UI5C 4ZLXA 4KZQC 4HKNC 4L0SC 4ZM0A 5ADTB 2ODKA 5ADSB 3HS2A 2A6QA 4UVPB 4L2GC 4HKIC 2ZIXB 3CTOA 3K33B 4UI3C 4UI4C 5C5RC 5C5PC 4KZLC 3OEIA 4L32C 4L10C 3G5OA 4L33C 4L0TC 4L2KC 5FPFC 4HLKC 5C5QC 4HKKB 4HLMC 4HLHC 4HLFC 4L31C 5ADQB 4L34C 4ZM2A 4HLGC 3KH2E 3HJ6A 4L0IC 4UI8C 3HRYA
chains in the Genus database with same CATH topology
4UI6C 4L09C 4HMHC 4KZUC 4L0VC 4UI7C 4HL5C 5ADRB 4L0BC 4L2FC 4UI5C 4KZQC 4HKNC 4L0SC 5ADTB 5ADSB 4UVPB 4L2GC 4HKIC 2ZIXB 4UI3C 4UI4C 5C5RC 5C5PC 4KZLC 4L32C 4L10C 4L33C 4L0TC 4L2KC 5FPFC 4HLKC 5C5QC 4HKKB 4HLMC 4HLHC 4HLFC 4L31C 5ADQB 4L34C 4HLGC 4L0IC 3HJ6A 4UI8C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UI6 C;  4L09 C;  4HMH C;  4KZU C;  4L0V C;  4UI7 C;  4HL5 C;  5ADR B;  4L0B C;  4L2F C;  4UI5 C;  4KZQ C;  4HKN C;  4L0S C;  5ADT B;  5ADS B;  4UVP B;  4L2G C;  4HKI C;  4UI3 C;  4UI4 C;  5C5R C;  5C5P C;  4KZL C;  4L32 C;  4L10 C;  4L33 C;  4L0T C;  4L2K C;  5FPF C;  4HLK C;  5C5Q C;  4HKK B;  4HLM C;  4HLH C;  4HLF C;  4L31 C;  5ADQ B;  4L34 C;  4HLG C;  4L0I C;  4UI8 C; 
#chains in the Genus database with same CATH topology
 3OEI E;  4UI6 C;  4L09 C;  4HMH C;  4KZU C;  3D55 A;  4L0V C;  4HL5 C;  4UI7 C;  5ADR B;  4L0B C;  4L2F C;  3K6Q A;  4UI5 C;  4ZLX A;  4KZQ C;  4HKN C;  4L0S C;  4ZM0 A;  5ADT B;  2ODK A;  5ADS B;  3HS2 A;  2A6Q A;  4UVP B;  4L2G C;  4HKI C;  2ZIX B;  3CTO A;  3K33 B;  4UI3 C;  4UI4 C;  5C5R C;  5C5P C;  4KZL C;  3OEI A;  4L32 C;  4L10 C;  3G5O A;  4L33 C;  4L0T C;  4L2K C;  5FPF C;  4HLK C;  5C5Q C;  4HKK B;  4HLM C;  4HLH C;  4HLF C;  4L31 C;  5ADQ B;  4L34 C;  4ZM2 A;  4HLG C;  3KH2 E;  3HJ6 A;  4L0I C;  4UI8 C;  3HRY A; 
#chains in the Genus database with same CATH homology
 4UI6 C;  4L09 C;  4HMH C;  4KZU C;  4L0V C;  4UI7 C;  4HL5 C;  5ADR B;  4L0B C;  4L2F C;  4UI5 C;  4KZQ C;  4HKN C;  4L0S C;  5ADT B;  5ADS B;  4UVP B;  4L2G C;  4HKI C;  2ZIX B;  4UI3 C;  4UI4 C;  5C5R C;  5C5P C;  4KZL C;  4L32 C;  4L10 C;  4L33 C;  4L0T C;  4L2K C;  5FPF C;  4HLK C;  5C5Q C;  4HKK B;  4HLM C;  4HLH C;  4HLF C;  4L31 C;  5ADQ B;  4L34 C;  4HLG C;  4L0I C;  3HJ6 A;  4UI8 C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...