4HWJA

Crystal structure of the human c3a desarg anaphylatoxin
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
75
structure length
75
Chain Sequence
VQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Complement C3
publication title Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.
pubmed doi rcsb
source organism Homo sapiens
total genus 26
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2012-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4hwjA00
4P3BA 4HWJA 4HW5A 2A73B 4FXKB 4WB2A 5B4PB 1CFAA 3HQAA 1KJSA 4WB3A 4I6OA 3KLSA 3CU7A 4P3AA 1C5AA 3HQBA 5JPNB 4P39A 2B39A 4UU9C
chains in the Genus database with same CATH superfamily
3VDXA 4P3BA 2Z16A 4PUSA 4HWJA 4HW5A 4IQ4A 5CQEA 4ITVA 2A73B 4FXKB 4WB2A 5B4PB 1CFAA 3HQAA 1AA7A 3MD2A 4D9JA 1KJSA 4WB3A 1EA3A 4I6OA 3KLSA 3CU7A 4P3AA 1C5AA 3HQBA 5JPMB 4FXGB 5JPNB 4P39A 2B39A 4UU9C
chains in the Genus database with same CATH topology
4P3BA 4HWJA 4HW5A 2A73B 4FXKB 4WB2A 5B4PB 1CFAA 3HQAA 1KJSA 4WB3A 4I6OA 3KLSA 3CU7A 4P3AA 1C5AA 3HQBA 5JPNB 4P39A 2B39A 4UU9C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P3B A;  4HWJ A;  4HW5 A;  2A73 B;  4FXK B;  4WB2 A;  5B4P B;  1CFA A;  3HQA A;  1KJS A;  4WB3 A;  4I6O A;  3KLS A;  3CU7 A;  4P3A A;  1C5A A;  3HQB A;  5JPN B;  4P39 A;  2B39 A;  4UU9 C; 
#chains in the Genus database with same CATH topology
 3VDX A;  4P3B A;  2Z16 A;  4PUS A;  4HWJ A;  4HW5 A;  4IQ4 A;  5CQE A;  4ITV A;  2A73 B;  4FXK B;  4WB2 A;  5B4P B;  1CFA A;  3HQA A;  1AA7 A;  3MD2 A;  4D9J A;  1KJS A;  4WB3 A;  1EA3 A;  4I6O A;  3KLS A;  3CU7 A;  4P3A A;  1C5A A;  3HQB A;  5JPM B;  4FXG B;  5JPN B;  4P39 A;  2B39 A;  4UU9 C; 
#chains in the Genus database with same CATH homology
 4P3B A;  4HWJ A;  4HW5 A;  2A73 B;  4FXK B;  4WB2 A;  5B4P B;  1CFA A;  3HQA A;  1KJS A;  4WB3 A;  4I6O A;  3KLS A;  3CU7 A;  4P3A A;  1C5A A;  3HQB A;  5JPN B;  4P39 A;  2B39 A;  4UU9 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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