4HXIB

Crystal structure of klhl3/cul3 complex
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
354
structure length
346
Chain Sequence
DEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMRTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEDYRQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kelch-like protein 3
publication title Structural and Functional Characterization of KLHL3/Cul3 complex and implications of FHHt mutations in Cul3 binding
rcsb
source organism Homo sapiens
molecule tags Protein binding
total genus 139
structure length 346
sequence length 354
ec nomenclature
pdb deposition date 2012-11-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB03
3DPLC 4P5OA 4APFB 1U6GA 1LDKB 3DQVC 4HXIB 4N9F3 4WQOD 3RTRA 1LDKA 4F52A 4A64A 1LDJA 4AP2B 4JGHD 4EOZB 2WZKA
chains in the Genus database with same CATH superfamily
4APFB 1U6GA 1LDKB 2WAUA 3CMLA 4AP2B 4JGHD 4F52A 2Y8DA 3DPLC 3DQVC 4N9F3 4NUVA 3RRCA 3RTRA 1LDKA 1LDJA 4EOZB 2WZKA 2XU0A 4WQOD 4YFSA 4P5OA 3BQIA 3BQLA 5F3JA 2B1EA 4HXIB 3CPZA 3BQKA 4A64A 2PFVA 4NUUA
chains in the Genus database with same CATH topology
3DPLC 4P5OA 4APFB 1U6GA 1LDKB 3DQVC 4HXIB 4N9F3 4WQOD 3RTRA 1LDKA 4F52A 4A64A 1LDJA 4AP2B 4JGHD 4EOZB 2WZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DPL C;  4P5O A;  4APF B;  1U6G A;  1LDK B;  3DQV C;  4HXI B;  4N9F 3;  4WQO D;  3RTR A;  1LDK A;  4F52 A;  4A64 A;  1LDJ A;  4AP2 B;  4JGH D;  4EOZ B;  2WZK A; 
#chains in the Genus database with same CATH topology
 4APF B;  1U6G A;  1LDK B;  2WAU A;  3CML A;  4AP2 B;  4JGH D;  4F52 A;  2Y8D A;  3DPL C;  3DQV C;  4N9F 3;  4NUV A;  3RRC A;  3RTR A;  1LDK A;  1LDJ A;  4EOZ B;  2WZK A;  2XU0 A;  4WQO D;  4YFS A;  4P5O A;  3BQI A;  3BQL A;  5F3J A;  2B1E A;  4HXI B;  3CPZ A;  3BQK A;  4A64 A;  2PFV A;  4NUU A; 
#chains in the Genus database with same CATH homology
 3DPL C;  4P5O A;  4APF B;  1U6G A;  1LDK B;  3DQV C;  4HXI B;  4N9F 3;  4WQO D;  3RTR A;  1LDK A;  4F52 A;  4A64 A;  1LDJ A;  4AP2 B;  4JGH D;  4EOZ B;  2WZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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