4HXIB

Crystal structure of klhl3/cul3 complex
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
354
structure length
346
Chain Sequence
DEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMRTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEDYRQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
molecule keywords Kelch-like protein 3
publication title Structural and Functional Characterization of KLHL3/Cul3 complex and implications of FHHt mutations in Cul3 binding
rcsb
source organism Homo sapiens
total genus 139
structure length 346
sequence length 354
ec nomenclature
pdb deposition date 2012-11-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB03
1LDKB 4WQOD 4JGHD 1LDJA 4HXIB 3DQVC 4P5OA 4AP2B 4A64A 1LDKA 2WZKA 1U6GA 4APFB 4EOZB 4N9F3 3DPLC 3RTRA 4F52A
chains in the Genus database with same CATH superfamily
1LDKB 3BQIA 4JGHD 1LDKA 2B1EA 2Y8DA 4WQOD 4YFSA 4NUVA 4EOZB 3CPZA 3RTRA 3BQKA 2PFVA 1LDJA 2XU0A 3BQLA 4HXIB 4P5OA 4AP2B 4F52A 1U6GA 4APFB 3DQVC 4NUUA 4A64A 2WAUA 2WZKA 5F3JA 3CMLA 4N9F3 3DPLC 3RRCA
chains in the Genus database with same CATH topology
1LDKB 4WQOD 4JGHD 1LDJA 4HXIB 3DQVC 4P5OA 4AP2B 4A64A 1LDKA 2WZKA 1U6GA 4APFB 4EOZB 4N9F3 3DPLC 3RTRA 4F52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LDK B;  4WQO D;  4JGH D;  1LDJ A;  4HXI B;  3DQV C;  4P5O A;  4AP2 B;  4A64 A;  1LDK A;  2WZK A;  1U6G A;  4APF B;  4EOZ B;  4N9F 3;  3DPL C;  3RTR A;  4F52 A; 
#chains in the Genus database with same CATH topology
 1LDK B;  3BQI A;  4JGH D;  1LDK A;  2B1E A;  2Y8D A;  4WQO D;  4YFS A;  4NUV A;  4EOZ B;  3CPZ A;  3RTR A;  3BQK A;  2PFV A;  1LDJ A;  2XU0 A;  3BQL A;  4HXI B;  4P5O A;  4AP2 B;  4F52 A;  1U6G A;  4APF B;  3DQV C;  4NUU A;  4A64 A;  2WAU A;  2WZK A;  5F3J A;  3CML A;  4N9F 3;  3DPL C;  3RRC A; 
#chains in the Genus database with same CATH homology
 1LDK B;  4WQO D;  4JGH D;  1LDJ A;  4HXI B;  3DQV C;  4P5O A;  4AP2 B;  4A64 A;  1LDK A;  2WZK A;  1U6G A;  4APF B;  4EOZ B;  4N9F 3;  3DPL C;  3RTR A;  4F52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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