4IDJA

S.aureus a-hemolysin monomer in complex with fab
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
287
structure length
276
Chain Sequence
IKTGTTDIGSNTTVKTGDLVTYDKENGMLKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Alpha-hemolysin
publication title Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 63
structure length 276
sequence length 287
ec nomenclature
pdb deposition date 2012-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4idjA00
3M3RA 4P1YA 4H56A 4J0OA 4IYTA 4P1XB 4U6VA 2YGTA 3B07A 3O44A 4IZLA 4IDJA 3LKFA 4P1YB 3ROHA 5K59C 3ANZA 3B07B 3M2LA 1PVLA 3M4EA 3M4DA 4YHDA 2QK7A 4TW1A 4Q7GA 5K59A 4P24A 7AHLA 1T5RA 2QK7B 4IYAA 1LKFA 4TW1B 4IYCA 2LKFA 4I0NA 4P1XA
chains in the Genus database with same CATH superfamily
3M3RA 4P1YA 4H56A 4J0OA 4IYTA 4P1XB 4U6VA 2YGTA 3B07A 3O44A 4IZLA 4IDJA 3LKFA 4P1YB 3ROHA 5K59C 3ANZA 3B07B 3M2LA 1PVLA 3M4EA 3M4DA 4YHDA 2QK7A 4TW1A 4Q7GA 5K59A 4P24A 7AHLA 1XEZA 1T5RA 2QK7B 4IYAA 1LKFA 4TW1B 4IYCA 2LKFA 4I0NA 4P1XA
chains in the Genus database with same CATH topology
3M3RA 4P1YA 4H56A 4J0OA 4IYTA 4P1XB 4U6VA 2YGTA 3B07A 3O44A 4IZLA 4IDJA 3LKFA 4P1YB 3ROHA 5K59C 3ANZA 3B07B 3M2LA 1PVLA 3M4EA 3M4DA 4YHDA 2QK7A 4TW1A 4Q7GA 5K59A 4P24A 7AHLA 1T5RA 2QK7B 4IYAA 1LKFA 4TW1B 4IYCA 2LKFA 4I0NA 4P1XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M3R A;  4P1Y A;  4H56 A;  4J0O A;  4IYT A;  4P1X B;  4U6V A;  2YGT A;  3B07 A;  3O44 A;  4IZL A;  4IDJ A;  3LKF A;  4P1Y B;  3ROH A;  5K59 C;  3ANZ A;  3B07 B;  3M2L A;  1PVL A;  3M4E A;  3M4D A;  4YHD A;  2QK7 A;  4TW1 A;  4Q7G A;  5K59 A;  4P24 A;  7AHL A;  1T5R A;  2QK7 B;  4IYA A;  1LKF A;  4TW1 B;  4IYC A;  2LKF A;  4I0N A;  4P1X A; 
#chains in the Genus database with same CATH topology
 3M3R A;  4P1Y A;  4H56 A;  4J0O A;  4IYT A;  4P1X B;  4U6V A;  2YGT A;  3B07 A;  3O44 A;  4IZL A;  4IDJ A;  3LKF A;  4P1Y B;  3ROH A;  5K59 C;  3ANZ A;  3B07 B;  3M2L A;  1PVL A;  3M4E A;  3M4D A;  4YHD A;  2QK7 A;  4TW1 A;  4Q7G A;  5K59 A;  4P24 A;  7AHL A;  1XEZ A;  1T5R A;  2QK7 B;  4IYA A;  1LKF A;  4TW1 B;  4IYC A;  2LKF A;  4I0N A;  4P1X A; 
#chains in the Genus database with same CATH homology
 3M3R A;  4P1Y A;  4H56 A;  4J0O A;  4IYT A;  4P1X B;  4U6V A;  2YGT A;  3B07 A;  3O44 A;  4IZL A;  4IDJ A;  3LKF A;  4P1Y B;  3ROH A;  5K59 C;  3ANZ A;  3B07 B;  3M2L A;  1PVL A;  3M4E A;  3M4D A;  4YHD A;  2QK7 A;  4TW1 A;  4Q7G A;  5K59 A;  4P24 A;  7AHL A;  1T5R A;  2QK7 B;  4IYA A;  1LKF A;  4TW1 B;  4IYC A;  2LKF A;  4I0N A;  4P1X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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