4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
223
structure length
223
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords tRNA (guanine-N(1)-)-methyltransferase
publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
source organism Anaplasma phagocytophilum
molecule tags Transferase/transferase inhibitor
total genus 66
structure length 223
sequence length 223
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
2CX8A 4YPXA 2EGWA 4X3LA 4L69A 1VHKA 4RG1A 1VHYA 3BBHA 4X3MA 4YVIA 4YQDA 5FAIA 2QWVA 1X7OA 1IPAA 4YVGA 1UAKA 4PZKA 5D9FA 1O6DA 3OIJA 3ONPA 1OY5A 3O7BA 4YQTA 4MCBA 2YY8A 3KTYA 3DCMX 4YQ9A 2EGVA 1GZ0A 3NK6A 3IC6A 4YQPA 1UAJA 4YQGA 4YQIA 4YQBA 4YQ3A 1NXZA 1ZJRA 4YQ4A 3KY7A 2O3AA 4MCCA 4H3ZA 3IEFA 4YPZA 4J3CA 1X7PA 3BBDA 3L8UA 3OINA 3AXZA 1V6ZA 3OIIA 3AIAA 3ILKA 3N4KA 4JALA 3GYQA 3NK7A 4YQCA 1NS5A 1J85A 2QMMA 1Z85A 3E5YA 5GM8A 3AI9X 1VH0A 4YQLA 4YQSA 3KNUA 2V3JA 1K3RA 4YPWA 2V3KA 4YVKA 3N4JA 4YQ1A 4CNGA 4E8BA 4XBOA 4YQOA 4YQKA 1TO0A 4KGNA 4YQ7A 2Z0YA 4IG6A 4JAKA 2HA8A 5GMBA 4H3YA 1MXIA 4YQRA 5GMCA 4KDZA 4CNDA 4YQ8A 1V2XA 4YQ6A 4YVJA 3KW2A 1P9PA 5CO4A 4YPYA 4FAKA 4YQ0A 4YQ5A 3QUVA 4YQJA 3BBEA 4YQNA 4YQ2A 4MCDA 4CNFA 4YVHA 1UAMA 4CNEA 4YQAA 1UALA 2I6DA 4YQQA
chains in the Genus database with same CATH superfamily
2CX8A 4YPXA 2EGWA 4X3LA 1JHGA 4L69A 1VHKA 4RG1A 1VHYA 3BBHA 4X3MA 4YVIA 1WRTR 4YQDA 5FAIA 2QWVA 1X7OA 1IPAA 1UAKA 4YVGA 4PZKA 5D9FA 3WRPA 1O6DA 3OIJA 3ONPA 1OY5A 3O7BA 4YQTA 4MCBA 4JWGA 2YY8A 3KTYA 3DCMX 4YQ9A 2EGVA 1GZ0A 3NK6A 3IC6A 4YQPA 1WRPR 1UAJA 4YQGA 4YQIA 4YQBA 4YQ3A 1NXZA 1ZJRA 4YQ4A 3KY7A 2O3AA 4JWFA 4MCCA 4H3ZA 3IEFA 2OZ9R 4YPZA 4JWJA 4J3CA 1X7PA 3BBDA 3L8UA 3OINA 3KORA 3AXZA 1V6ZA 3OIIA 3AIAA 3ILKA 1CO0A 3N4KA 4JALA 3GYQA 3NK7A 4YQCA 1NS5A 1J85A 2QMMA 1Z85A 3E5YA 5GM8A 1WRSR 3FRWA 3AI9X 1VH0A 3G1CA 4YQLA 4YQSA 3KNUA 1ZT9A 2V3JA 1K3RA 3SSXN 4YPWA 2V3KA 4YVKA 3N4JA 4YQ1A 4CNGA 4E8BA 4XBOA 4YQOA 4YQKA 1TO0A 4KGNA 4YQ7A 2Z0YA 4IG6A 4JAKA 4JWHA 2HA8A 5GMBA 4H3YA 1MXIA 4YQRA 5GMCA 4KDZA 4CNDA 4YQ8A 1V2XA 2XDIA 4YQ6A 4YVJA 3KW2A 1P9PA 5CO4A 4YPYA 1MI7R 4FAKA 4YQ0A 4YQ5A 3QUVA 4YQJA 3BBEA 4YQNA 4YQ2A 3SSWN 1RCSA 4MCDA 4CNFA 4YVHA 1TROA 1UAMA 4CNEA 4YQAA 1UALA 1TRRA 2I6DA 4YQQA 4FMWA
chains in the Genus database with same CATH topology
2CX8A 4YPXA 2EGWA 4X3LA 4L69A 1VHKA 4RG1A 1VHYA 3BBHA 4X3MA 4YVIA 4YQDA 5FAIA 2QWVA 1X7OA 1IPAA 4YVGA 1UAKA 4PZKA 5D9FA 1O6DA 3OIJA 3ONPA 1OY5A 3O7BA 4YQTA 4MCBA 4JWGA 2YY8A 3KTYA 3DCMX 4YQ9A 2EGVA 1GZ0A 3NK6A 3IC6A 4YQPA 1UAJA 4YQGA 4YQIA 4YQBA 4YQ3A 1NXZA 1ZJRA 4YQ4A 3KY7A 2O3AA 4JWFA 4MCCA 4H3ZA 3IEFA 4YPZA 4JWJA 4J3CA 1X7PA 3BBDA 3L8UA 3OINA 3AXZA 1V6ZA 3OIIA 3AIAA 3ILKA 3N4KA 4JALA 3GYQA 3NK7A 4YQCA 1NS5A 1J85A 2QMMA 1Z85A 3E5YA 5GM8A 3AI9X 1VH0A 4YQLA 4YQSA 3KNUA 2V3JA 1K3RA 4YPWA 2V3KA 4YVKA 3N4JA 4YQ1A 4CNGA 4E8BA 4XBOA 4YQOA 4YQKA 1TO0A 4KGNA 4YQ7A 2Z0YA 4IG6A 4JAKA 4JWHA 2HA8A 5GMBA 4H3YA 1MXIA 4YQRA 5GMCA 4KDZA 4CNDA 4YQ8A 1V2XA 4YQ6A 4YVJA 3KW2A 1P9PA 5CO4A 4YPYA 4FAKA 4YQ0A 4YQ5A 3QUVA 4YQJA 3BBEA 4YQNA 4YQ2A 4MCDA 4CNFA 4YVHA 1UAMA 4CNEA 4YQAA 1UALA 2I6DA 4YQQA 4FMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CX8 A;  4YPX A;  2EGW A;  4X3L A;  4L69 A;  1VHK A;  4RG1 A;  1VHY A;  3BBH A;  4X3M A;  4YVI A;  4YQD A;  5FAI A;  2QWV A;  1X7O A;  1IPA A;  4YVG A;  1UAK A;  4PZK A;  5D9F A;  1O6D A;  3OIJ A;  3ONP A;  1OY5 A;  3O7B A;  4YQT A;  4MCB A;  2YY8 A;  3KTY A;  3DCM X;  4YQ9 A;  2EGV A;  1GZ0 A;  3NK6 A;  3IC6 A;  4YQP A;  1UAJ A;  4YQG A;  4YQI A;  4YQB A;  4YQ3 A;  1NXZ A;  1ZJR A;  4YQ4 A;  3KY7 A;  2O3A A;  4MCC A;  4H3Z A;  3IEF A;  4YPZ A;  4J3C A;  1X7P A;  3BBD A;  3L8U A;  3OIN A;  3AXZ A;  1V6Z A;  3OII A;  3AIA A;  3ILK A;  3N4K A;  4JAL A;  3GYQ A;  3NK7 A;  4YQC A;  1NS5 A;  1J85 A;  2QMM A;  1Z85 A;  3E5Y A;  5GM8 A;  3AI9 X;  1VH0 A;  4YQL A;  4YQS A;  3KNU A;  2V3J A;  1K3R A;  4YPW A;  2V3K A;  4YVK A;  3N4J A;  4YQ1 A;  4CNG A;  4E8B A;  4XBO A;  4YQO A;  4YQK A;  1TO0 A;  4KGN A;  4YQ7 A;  2Z0Y A;  4IG6 A;  4JAK A;  2HA8 A;  5GMB A;  4H3Y A;  1MXI A;  4YQR A;  5GMC A;  4KDZ A;  4CND A;  4YQ8 A;  1V2X A;  4YQ6 A;  4YVJ A;  3KW2 A;  1P9P A;  5CO4 A;  4YPY A;  4FAK A;  4YQ0 A;  4YQ5 A;  3QUV A;  4YQJ A;  3BBE A;  4YQN A;  4YQ2 A;  4MCD A;  4CNF A;  4YVH A;  1UAM A;  4CNE A;  4YQA A;  1UAL A;  2I6D A;  4YQQ A; 
#chains in the Genus database with same CATH topology
 2CX8 A;  4YPX A;  2EGW A;  4X3L A;  1JHG A;  4L69 A;  1VHK A;  4RG1 A;  1VHY A;  3BBH A;  4X3M A;  4YVI A;  1WRT R;  4YQD A;  5FAI A;  2QWV A;  1X7O A;  1IPA A;  1UAK A;  4YVG A;  4PZK A;  5D9F A;  3WRP A;  1O6D A;  3OIJ A;  3ONP A;  1OY5 A;  3O7B A;  4YQT A;  4MCB A;  4JWG A;  2YY8 A;  3KTY A;  3DCM X;  4YQ9 A;  2EGV A;  1GZ0 A;  3NK6 A;  3IC6 A;  4YQP A;  1WRP R;  1UAJ A;  4YQG A;  4YQI A;  4YQB A;  4YQ3 A;  1NXZ A;  1ZJR A;  4YQ4 A;  3KY7 A;  2O3A A;  4JWF A;  4MCC A;  4H3Z A;  3IEF A;  2OZ9 R;  4YPZ A;  4JWJ A;  4J3C A;  1X7P A;  3BBD A;  3L8U A;  3OIN A;  3KOR A;  3AXZ A;  1V6Z A;  3OII A;  3AIA A;  3ILK A;  1CO0 A;  3N4K A;  4JAL A;  3GYQ A;  3NK7 A;  4YQC A;  1NS5 A;  1J85 A;  2QMM A;  1Z85 A;  3E5Y A;  5GM8 A;  1WRS R;  3FRW A;  3AI9 X;  1VH0 A;  3G1C A;  4YQL A;  4YQS A;  3KNU A;  1ZT9 A;  2V3J A;  1K3R A;  3SSX N;  4YPW A;  2V3K A;  4YVK A;  3N4J A;  4YQ1 A;  4CNG A;  4E8B A;  4XBO A;  4YQO A;  4YQK A;  1TO0 A;  4KGN A;  4YQ7 A;  2Z0Y A;  4IG6 A;  4JAK A;  4JWH A;  2HA8 A;  5GMB A;  4H3Y A;  1MXI A;  4YQR A;  5GMC A;  4KDZ A;  4CND A;  4YQ8 A;  1V2X A;  2XDI A;  4YQ6 A;  4YVJ A;  3KW2 A;  1P9P A;  5CO4 A;  4YPY A;  1MI7 R;  4FAK A;  4YQ0 A;  4YQ5 A;  3QUV A;  4YQJ A;  3BBE A;  4YQN A;  4YQ2 A;  3SSW N;  1RCS A;  4MCD A;  4CNF A;  4YVH A;  1TRO A;  1UAM A;  4CNE A;  4YQA A;  1UAL A;  1TRR A;  2I6D A;  4YQQ A;  4FMW A; 
#chains in the Genus database with same CATH homology
 2CX8 A;  4YPX A;  2EGW A;  4X3L A;  4L69 A;  1VHK A;  4RG1 A;  1VHY A;  3BBH A;  4X3M A;  4YVI A;  4YQD A;  5FAI A;  2QWV A;  1X7O A;  1IPA A;  4YVG A;  1UAK A;  4PZK A;  5D9F A;  1O6D A;  3OIJ A;  3ONP A;  1OY5 A;  3O7B A;  4YQT A;  4MCB A;  4JWG A;  2YY8 A;  3KTY A;  3DCM X;  4YQ9 A;  2EGV A;  1GZ0 A;  3NK6 A;  3IC6 A;  4YQP A;  1UAJ A;  4YQG A;  4YQI A;  4YQB A;  4YQ3 A;  1NXZ A;  1ZJR A;  4YQ4 A;  3KY7 A;  2O3A A;  4JWF A;  4MCC A;  4H3Z A;  3IEF A;  4YPZ A;  4JWJ A;  4J3C A;  1X7P A;  3BBD A;  3L8U A;  3OIN A;  3AXZ A;  1V6Z A;  3OII A;  3AIA A;  3ILK A;  3N4K A;  4JAL A;  3GYQ A;  3NK7 A;  4YQC A;  1NS5 A;  1J85 A;  2QMM A;  1Z85 A;  3E5Y A;  5GM8 A;  3AI9 X;  1VH0 A;  4YQL A;  4YQS A;  3KNU A;  2V3J A;  1K3R A;  4YPW A;  2V3K A;  4YVK A;  3N4J A;  4YQ1 A;  4CNG A;  4E8B A;  4XBO A;  4YQO A;  4YQK A;  1TO0 A;  4KGN A;  4YQ7 A;  2Z0Y A;  4IG6 A;  4JAK A;  4JWH A;  2HA8 A;  5GMB A;  4H3Y A;  1MXI A;  4YQR A;  5GMC A;  4KDZ A;  4CND A;  4YQ8 A;  1V2X A;  4YQ6 A;  4YVJ A;  3KW2 A;  1P9P A;  5CO4 A;  4YPY A;  4FAK A;  4YQ0 A;  4YQ5 A;  3QUV A;  4YQJ A;  3BBE A;  4YQN A;  4YQ2 A;  4MCD A;  4CNF A;  4YVH A;  1UAM A;  4CNE A;  4YQA A;  1UAL A;  2I6D A;  4YQQ A;  4FMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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