4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
223
structure length
223
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
molecule tags Transferase/transferase inhibitor
source organism Anaplasma phagocytophilum
total genus 66
structure length 223
sequence length 223
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
3OIJA 3KNUA 3QUVA 1OY5A 4YQQA 4JALA 2V3KA 4MCDA 3O7BA 3IEFA 5GMBA 1ZJRA 3BBDA 1IPAA 3IC6A 2YY8A 4X3MA 4YVGA 4YQTA 1MXIA 4XBOA 1VH0A 4YQPA 4YQ6A 4YQCA 4YVIA 4PZKA 2I6DA 1VHYA 5GMCA 4YQ2A 3GYQA 1UAKA 4YVJA 4J3CA 1Z85A 1J85A 3AI9X 3BBEA 2V3JA 4YQ9A 4X3LA 3L8UA 4YQKA 4YQAA 2QMMA 4H3ZA 1V6ZA 3ONPA 3DCMX 4CNDA 4YPZA 4YQ4A 3N4JA 3OIIA 1X7PA 1UAJA 1X7OA 4YQNA 1GZ0A 4YQRA 4YQOA 2QWVA 4E8BA 4KGNA 3NK7A 4YQSA 3OINA 4YQ5A 4CNGA 4YQDA 4YVHA 1O6DA 1VHKA 1V2XA 3E5YA 1NS5A 4RG1A 4IG6A 4YQBA 4YQIA 4YQGA 4YQ0A 5FAIA 4YQ8A 3KW2A 4YPWA 4MCCA 2Z0YA 4YQ1A 2O3AA 5CO4A 1NXZA 3AIAA 2HA8A 3KTYA 3N4KA 3AXZA 3ILKA 4CNFA 3BBHA 4L69A 4MCBA 4JAKA 5GM8A 4YPYA 2EGWA 5D9FA 4FAKA 1UAMA 4KDZA 4YQLA 2EGVA 2CX8A 3NK6A 1UALA 1K3RA 4H3YA 4YPXA 1P9PA 3KY7A 4YVKA 4YQ3A 4YQJA 4CNEA 1TO0A 4YQ7A
chains in the Genus database with same CATH superfamily
3OIJA 3KNUA 3SSWN 3QUVA 1OY5A 4YQQA 4JALA 2V3KA 1MI7R 4MCDA 1JHGA 3O7BA 3IEFA 5GMBA 1ZJRA 3BBDA 1IPAA 3IC6A 2YY8A 4X3MA 4YVGA 3FRWA 4YQTA 1MXIA 4XBOA 1VH0A 4YQPA 3KORA 4YQ6A 4YQCA 1WRPR 4YVIA 4PZKA 2I6DA 1VHYA 5GMCA 4YQ2A 3GYQA 1UAKA 4YVJA 4J3CA 1Z85A 1J85A 3AI9X 3BBEA 2V3JA 4YQ9A 4X3LA 3L8UA 4YQKA 4YQAA 2QMMA 1WRSR 4H3ZA 1V6ZA 3ONPA 3DCMX 4CNDA 4JWHA 4YPZA 1ZT9A 4JWFA 4YQ4A 3N4JA 3OIIA 1X7PA 1UAJA 1X7OA 4YQNA 2OZ9R 1GZ0A 4YQRA 4YQOA 2QWVA 4E8BA 4KGNA 3NK7A 1TRRA 3G1CA 4YQSA 3OINA 4YQ5A 4CNGA 4YQDA 4YVHA 1O6DA 1TROA 1VHKA 1CO0A 1V2XA 1NS5A 3E5YA 4RG1A 4IG6A 4YQBA 4JWGA 4YQIA 4YQGA 4FMWA 4YQ0A 3SSXN 4YQ8A 5FAIA 3KW2A 4YPWA 4MCCA 2Z0YA 4YQ1A 2O3AA 4JWJA 5CO4A 1NXZA 3AIAA 2HA8A 3KTYA 3N4KA 3AXZA 3ILKA 4CNFA 3BBHA 4L69A 4MCBA 4JAKA 5GM8A 4YPYA 2EGWA 5D9FA 4FAKA 1UAMA 4KDZA 1WRTR 1RCSA 4YQLA 2EGVA 2CX8A 3NK6A 1UALA 1K3RA 4H3YA 4YPXA 1P9PA 3KY7A 4YVKA 2XDIA 4YQ3A 4YQJA 4CNEA 3WRPA 1TO0A 4YQ7A
chains in the Genus database with same CATH topology
3OIJA 3KNUA 3QUVA 1OY5A 4YQQA 4JALA 2V3KA 4MCDA 3O7BA 3IEFA 5GMBA 1ZJRA 3BBDA 1IPAA 3IC6A 2YY8A 4X3MA 4YVGA 4YQTA 1MXIA 4XBOA 1VH0A 4YQPA 4YQ6A 4YQCA 4YVIA 4PZKA 2I6DA 1VHYA 5GMCA 4YQ2A 3GYQA 1UAKA 4YVJA 4J3CA 1Z85A 1J85A 3AI9X 3BBEA 2V3JA 4YQ9A 4X3LA 3L8UA 4YQKA 4YQAA 2QMMA 4H3ZA 1V6ZA 3ONPA 3DCMX 4CNDA 4JWHA 4YPZA 4JWFA 4YQ4A 3N4JA 3OIIA 1X7PA 1UAJA 1X7OA 4YQNA 1GZ0A 4YQRA 4YQOA 2QWVA 4E8BA 4KGNA 3NK7A 4YQSA 3OINA 4YQ5A 4CNGA 4YQDA 4YVHA 1O6DA 1VHKA 1V2XA 3E5YA 1NS5A 4RG1A 4IG6A 4YQBA 4JWGA 4YQIA 4YQGA 4FMWA 4YQ0A 5FAIA 4YQ8A 3KW2A 4YPWA 4MCCA 2Z0YA 4YQ1A 2O3AA 4JWJA 5CO4A 1NXZA 3AIAA 2HA8A 3KTYA 3N4KA 3AXZA 3ILKA 4CNFA 3BBHA 4L69A 4MCBA 4JAKA 5GM8A 4YPYA 2EGWA 5D9FA 4FAKA 1UAMA 4KDZA 4YQLA 2EGVA 2CX8A 3NK6A 1UALA 1K3RA 4H3YA 4YPXA 1P9PA 3KY7A 4YVKA 4YQ3A 4YQJA 4CNEA 1TO0A 4YQ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OIJ A;  3KNU A;  3QUV A;  1OY5 A;  4YQQ A;  4JAL A;  2V3K A;  4MCD A;  3O7B A;  3IEF A;  5GMB A;  1ZJR A;  3BBD A;  1IPA A;  3IC6 A;  2YY8 A;  4X3M A;  4YVG A;  4YQT A;  1MXI A;  4XBO A;  1VH0 A;  4YQP A;  4YQ6 A;  4YQC A;  4YVI A;  4PZK A;  2I6D A;  1VHY A;  5GMC A;  4YQ2 A;  3GYQ A;  1UAK A;  4YVJ A;  4J3C A;  1Z85 A;  1J85 A;  3AI9 X;  3BBE A;  2V3J A;  4YQ9 A;  4X3L A;  3L8U A;  4YQK A;  4YQA A;  2QMM A;  4H3Z A;  1V6Z A;  3ONP A;  3DCM X;  4CND A;  4YPZ A;  4YQ4 A;  3N4J A;  3OII A;  1X7P A;  1UAJ A;  1X7O A;  4YQN A;  1GZ0 A;  4YQR A;  4YQO A;  2QWV A;  4E8B A;  4KGN A;  3NK7 A;  4YQS A;  3OIN A;  4YQ5 A;  4CNG A;  4YQD A;  4YVH A;  1O6D A;  1VHK A;  1V2X A;  3E5Y A;  1NS5 A;  4RG1 A;  4IG6 A;  4YQB A;  4YQI A;  4YQG A;  4YQ0 A;  5FAI A;  4YQ8 A;  3KW2 A;  4YPW A;  4MCC A;  2Z0Y A;  4YQ1 A;  2O3A A;  5CO4 A;  1NXZ A;  3AIA A;  2HA8 A;  3KTY A;  3N4K A;  3AXZ A;  3ILK A;  4CNF A;  3BBH A;  4L69 A;  4MCB A;  4JAK A;  5GM8 A;  4YPY A;  2EGW A;  5D9F A;  4FAK A;  1UAM A;  4KDZ A;  4YQL A;  2EGV A;  2CX8 A;  3NK6 A;  1UAL A;  1K3R A;  4H3Y A;  4YPX A;  1P9P A;  3KY7 A;  4YVK A;  4YQ3 A;  4YQJ A;  4CNE A;  1TO0 A;  4YQ7 A; 
#chains in the Genus database with same CATH topology
 3OIJ A;  3KNU A;  3SSW N;  3QUV A;  1OY5 A;  4YQQ A;  4JAL A;  2V3K A;  1MI7 R;  4MCD A;  1JHG A;  3O7B A;  3IEF A;  5GMB A;  1ZJR A;  3BBD A;  1IPA A;  3IC6 A;  2YY8 A;  4X3M A;  4YVG A;  3FRW A;  4YQT A;  1MXI A;  4XBO A;  1VH0 A;  4YQP A;  3KOR A;  4YQ6 A;  4YQC A;  1WRP R;  4YVI A;  4PZK A;  2I6D A;  1VHY A;  5GMC A;  4YQ2 A;  3GYQ A;  1UAK A;  4YVJ A;  4J3C A;  1Z85 A;  1J85 A;  3AI9 X;  3BBE A;  2V3J A;  4YQ9 A;  4X3L A;  3L8U A;  4YQK A;  4YQA A;  2QMM A;  1WRS R;  4H3Z A;  1V6Z A;  3ONP A;  3DCM X;  4CND A;  4JWH A;  4YPZ A;  1ZT9 A;  4JWF A;  4YQ4 A;  3N4J A;  3OII A;  1X7P A;  1UAJ A;  1X7O A;  4YQN A;  2OZ9 R;  1GZ0 A;  4YQR A;  4YQO A;  2QWV A;  4E8B A;  4KGN A;  3NK7 A;  1TRR A;  3G1C A;  4YQS A;  3OIN A;  4YQ5 A;  4CNG A;  4YQD A;  4YVH A;  1O6D A;  1TRO A;  1VHK A;  1CO0 A;  1V2X A;  1NS5 A;  3E5Y A;  4RG1 A;  4IG6 A;  4YQB A;  4JWG A;  4YQI A;  4YQG A;  4FMW A;  4YQ0 A;  3SSX N;  4YQ8 A;  5FAI A;  3KW2 A;  4YPW A;  4MCC A;  2Z0Y A;  4YQ1 A;  2O3A A;  4JWJ A;  5CO4 A;  1NXZ A;  3AIA A;  2HA8 A;  3KTY A;  3N4K A;  3AXZ A;  3ILK A;  4CNF A;  3BBH A;  4L69 A;  4MCB A;  4JAK A;  5GM8 A;  4YPY A;  2EGW A;  5D9F A;  4FAK A;  1UAM A;  4KDZ A;  1WRT R;  1RCS A;  4YQL A;  2EGV A;  2CX8 A;  3NK6 A;  1UAL A;  1K3R A;  4H3Y A;  4YPX A;  1P9P A;  3KY7 A;  4YVK A;  2XDI A;  4YQ3 A;  4YQJ A;  4CNE A;  3WRP A;  1TO0 A;  4YQ7 A; 
#chains in the Genus database with same CATH homology
 3OIJ A;  3KNU A;  3QUV A;  1OY5 A;  4YQQ A;  4JAL A;  2V3K A;  4MCD A;  3O7B A;  3IEF A;  5GMB A;  1ZJR A;  3BBD A;  1IPA A;  3IC6 A;  2YY8 A;  4X3M A;  4YVG A;  4YQT A;  1MXI A;  4XBO A;  1VH0 A;  4YQP A;  4YQ6 A;  4YQC A;  4YVI A;  4PZK A;  2I6D A;  1VHY A;  5GMC A;  4YQ2 A;  3GYQ A;  1UAK A;  4YVJ A;  4J3C A;  1Z85 A;  1J85 A;  3AI9 X;  3BBE A;  2V3J A;  4YQ9 A;  4X3L A;  3L8U A;  4YQK A;  4YQA A;  2QMM A;  4H3Z A;  1V6Z A;  3ONP A;  3DCM X;  4CND A;  4JWH A;  4YPZ A;  4JWF A;  4YQ4 A;  3N4J A;  3OII A;  1X7P A;  1UAJ A;  1X7O A;  4YQN A;  1GZ0 A;  4YQR A;  4YQO A;  2QWV A;  4E8B A;  4KGN A;  3NK7 A;  4YQS A;  3OIN A;  4YQ5 A;  4CNG A;  4YQD A;  4YVH A;  1O6D A;  1VHK A;  1V2X A;  3E5Y A;  1NS5 A;  4RG1 A;  4IG6 A;  4YQB A;  4JWG A;  4YQI A;  4YQG A;  4FMW A;  4YQ0 A;  5FAI A;  4YQ8 A;  3KW2 A;  4YPW A;  4MCC A;  2Z0Y A;  4YQ1 A;  2O3A A;  4JWJ A;  5CO4 A;  1NXZ A;  3AIA A;  2HA8 A;  3KTY A;  3N4K A;  3AXZ A;  3ILK A;  4CNF A;  3BBH A;  4L69 A;  4MCB A;  4JAK A;  5GM8 A;  4YPY A;  2EGW A;  5D9F A;  4FAK A;  1UAM A;  4KDZ A;  4YQL A;  2EGV A;  2CX8 A;  3NK6 A;  1UAL A;  1K3R A;  4H3Y A;  4YPX A;  1P9P A;  3KY7 A;  4YVK A;  4YQ3 A;  4YQJ A;  4CNE A;  1TO0 A;  4YQ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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