4IHEA

Crystal structure of uncleaved thnt t282a
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
372
structure length
358
Chain Sequence
GGVPGPHNGLTDVPGVRVGHAGRTGDGWLTGVTVVLAPPGGAVAAVDVRGGGPGTRETDALDPRNLVQTIDAVVLTGGSAFGLDAAGGVAAWLEEQGRGFPVGADPSQVVPVVPAAALFDLGRGGTWRARPDAALGRAAVEAAAARPEGDPVEQGGVGAGTGAVVGGLKGGIGTASVVLDSGATVAALAAVNAAGSAVDPATGVLYGARTGLPGEFAGYGVPDAIGADTHARARARLAEAAEETARRRAGGAATLNATLAVVATDATLTRAQAQKLAGTAHDGLARAVRPVHLLSDGDTVFALSTGRRPLLHLEAGALNEVLAAGADVLTRAVVHAVLAATGVDTPGGVHPSYRELYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords ThnT protein
publication title Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT.
pubmed doi rcsb
source organism Streptomyces cattleya
total genus 117
structure length 358
sequence length 372
chains with identical sequence B
ec nomenclature ec 3.5.1.92: Pantetheine hydrolase.
pdb deposition date 2012-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03576 Peptidase_S58 Peptidase family S58
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.70.12 Alpha Beta 4-Layer Sandwich L-amino peptidase D-ALA esterase/amidase L-amino peptidase D-ALA esterase/amidase 4iheA00
2DRHA 3AXGA 1B65A 3NFBA 3N5IA 3N2WA 3IT4A 1VZ6A 4IHDA 3IT6A 3NDVA 2YEPA 3N33A 1VZ8A 1VZ7A 3S3UA 4IHEA 1VRAA 3TM1A 3TM2A 2V4IA 2VZKA
chains in the Genus database with same CATH superfamily
2DRHA 3AXGA 1B65A 3NFBA 3N5IA 3N2WA 3IT4A 1VZ6A 4IHDA 3IT6A 3NDVA 2YEPA 3N33A 1VZ8A 1VZ7A 3S3UA 4IHEA 1VRAA 3TM1A 3TM2A 2V4IA 2VZKA
chains in the Genus database with same CATH topology
2DRHA 3AXGA 1B65A 3NFBA 3N5IA 3N2WA 3IT4A 1VZ6A 4IHDA 3IT6A 3NDVA 2YEPA 3N33A 1VZ8A 1VZ7A 3S3UA 4IHEA 1VRAA 3TM1A 3TM2A 2V4IA 2VZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DRH A;  3AXG A;  1B65 A;  3NFB A;  3N5I A;  3N2W A;  3IT4 A;  1VZ6 A;  4IHD A;  3IT6 A;  3NDV A;  2YEP A;  3N33 A;  1VZ8 A;  1VZ7 A;  3S3U A;  4IHE A;  1VRA A;  3TM1 A;  3TM2 A;  2V4I A;  2VZK A; 
#chains in the Genus database with same CATH topology
 2DRH A;  3AXG A;  1B65 A;  3NFB A;  3N5I A;  3N2W A;  3IT4 A;  1VZ6 A;  4IHD A;  3IT6 A;  3NDV A;  2YEP A;  3N33 A;  1VZ8 A;  1VZ7 A;  3S3U A;  4IHE A;  1VRA A;  3TM1 A;  3TM2 A;  2V4I A;  2VZK A; 
#chains in the Genus database with same CATH homology
 2DRH A;  3AXG A;  1B65 A;  3NFB A;  3N5I A;  3N2W A;  3IT4 A;  1VZ6 A;  4IHD A;  3IT6 A;  3NDV A;  2YEP A;  3N33 A;  1VZ8 A;  1VZ7 A;  3S3U A;  4IHE A;  1VRA A;  3TM1 A;  3TM2 A;  2V4I A;  2VZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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