4IJDA

Crystal structure of methyltransferase domain of human pr domain-containing protein 9
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
219
structure length
215
Chain Sequence
SEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANNGYSWLITKGRNCYEYVDGKDKSWANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWYGDEYGQELGIKWGSKWKKELMPKPEIHPCPSCCLAFSSQKFLSQHVERNHSS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of methyltransferase domain of human PR domain-containing protein 9
rcsb
molecule keywords Histone-lysine N-methyltransferase PRDM9
molecule tags Transferase
source organism Homo sapiens
total genus 55
structure length 215
sequence length 219
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2012-12-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 4ijdA01
3.30.160.60 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain Classic Zinc Finger 4ijdA02
2YTGA 3S7DA 1ZKKA 2F69A 2EL5A 2A25A 2EMWA 2EMBA 2EMGA 4FMUA 2EPXA 4YPAA 2IGQA 1G2FC 3QWPA 2EM6A 2EOJA 3MO2A 5HI7A 2R1FA 3RIBA 5F5EA 2MKDA 3OS5A 3M54A 2EM2A 4FK5C 3PDNA 4R2EA 5JJ0A 4R2PA 2BB8A 1A1JA 1JK2A 1O9SA 5T0MA 2YRHA 2EL6A 3F9XA 3S7FA 2R3AA 2GLIA 1TF3A 1AAYA 1MVXA 1A1FA 2EN2A 2EN7A 4NVQA 5KL6A 1MT6A 4IJ8A 3OOIA 3EPLA 3UK3C 2WBTA 5KL3A 4J7IA 2EMHA 1B69A 2QPWA 2JV0A 1F2IG 2EOMA 5ARGA 3DB5A 4QEOA 1UN6B 5EG2A 2RPCA 2EM4A 2YSPA 5KL7A 3M55A 1YUJA 3FPDA 2CTDA 2EM0A 5EX0A 4M9VC 2NABA 2EPRA 1X6HA 5JINA 2YTIA 3EPHA 3EP0A 3QWWA 3KMAA 1A1HA 4YNMA 5KJMA 2EN3A 2RFIA 2M9AA 4JLGA 5CCLA 5KL4A 4H12A 3F9YA 2YRMA 2EOSA 2EP3A 4WSGA 1N3JA 1MUFA 1RMDA 4YNPA 3TG4A 3IHXA 1A1KA 2EN1A 5KL5A 5F6LA 4O6FA 2EPUA 3VUZA 2LVHA 2ELYA 2YTEA 3TG5A 2ENCA 1MEYC 2WBUA 2EOXA 4YPUA 3S7JA 5LSZA 1N6AA 3SW9A 2EMZA 1H3IA 4R2AA 4F2JC 2YTJA 2WBSA 4O30A 4R2CA 2DRPA 3KMJA 2EQ1A 4NJ5A 3K5KA 2EM7A 5KJLA 3MHSC 2YTQA 2EOOA 2EOYA 2YRKA 5F59A 3HNAA 5AYFA 5T5GA 3F9ZA 2D9HA 2EPZA 2EMXA 4J83A 3MO0A 3RQ4A 2MKNA 5EX3A 2EORA 1MVHA 1JK1A 2EOQA 1BBOA 4LDGA 3M57A 3EPKA 5KL2A 4RZ0A 2ENAA 2EOHA 4IJDA 1WJPA 1X5WA 2YSOA 5JHNA 4JDSA 4MI5A 5HQ8A 2CSHA 4GZNC 1X3CA 2EMYA 4J8OA 3N71A 3S8PA 2EPPA 3BO5A 3VHTB 2I13A 1DGCA 3KMTA 3MEKA 1G2DC 3CBPA 2HGHA 3CBMA 1X6EA 2DLQA 2PRTA 5CCMA 2LO3A 2LCEA 2EM8A 1N6CA 4F6NA 2EM3A 4YPEA 2VRDA 5KJKA 2EMLA 1LLMC 1BB8A 1A1LA 2EL4A 4C1QA 4YNDA 1ML9A 2EMKA 2JP9A 2EPAA 2YTFA 4X9JA 4BUPA 2EOEA 2EJ4A 2EM5A 4IS1C 2E72A 3M5AA 2CT1A 2W5ZA 2ADRA 1YUIA 1NCSA 2EM9A 2YTNA 2EE8A 1TF6A 4QEPA 4WUYA 5F6KC 2WCC3 5JIYA 4R2QA 3RAYA 2LT7A 3DALA 2O8JA 2RSIA 2YU8A 1ZR9A 4R2DA 3EPJA 5CPRB 1XQHA 1A1IA 3M53A 4QENA 2YU5A 2J7JA 1PEGA 3RU0A 2DLKA 2W5YA 2EOZA 5LSXA 2EN6A 3M56A 3OXFA 3MO5A 1X6FA 4R2SA 2DMIA 5TH7A 2ENHA 1TN9A 2G46A 1A1GA 3CBOA 2EN8A 2ELZA 2EOFA 3MHHC 1UBDC 2EQ3A 2EN4A 2YTOA 1ZAAC 4E47A 1ZU1A 4I51A 3SWCA 2EPCA 2DGCA 3OPEA 2EQ0A 3S7BA 3OXGA 5KJNA 5ARFA 2EMIA 3M59A 2EMCA 2EMAA 3OXLA 2YTPA 3QWVA 1Z1BA 1KJKA 5TEGA 2LV2A 3M58A 2GHFA 2YTDA 3M99B 5T0KA 2JPAA 5TTFA 4Z4PA 1YSAC 2EOIA 1P47A 4AU7A 3F9WA 2MDGA 4F6MA 2EMFA 3RJWA 4J7FA 4MI0A 2BQZA 4R2RA 3VV0A
chains in the Genus database with same CATH superfamily
2YTGA 3H09A 3S7DA 1ZKKA 2F69A 2RSMA 1N32E 4J8ZA 2EL5A 3AUZA 2UUCE 2A25A 1NEIA 2EMWA 2EMBA 2EMGA 3K6QA 2EZ6A 3HTXA 4LU9A 2L3JA 4YY3E 4FMUA 2EPXA 2DMYA 4YPAA 2IGQA 5IWAE 4YHHE 1G2FC 3QWPA 2EM6A 2EOJA 3MO2A 5HI7A 1YPNA 2R1FA 2V89A 3RIBA 1N3GA 5F5EA 2MKDA 4LFCE 3OS5A 4N4RB 2EPLX 3M54A 2EM2A 3ZOQB 4FK5C 3PDNA 1EH7A 4R2EA 4LF4E 3ECRA 5JJ0A 2DB2A 3QG5C 4R2PA 2BB8A 1A1JA 4NZVA 1JK2A 1O9SA 5T0MA 4DR1E 2IHR1 2LE2A 4LF9E 2YRHA 2EL6A 5FLXC 3F9XA 3S7FA 3LMLA 2ZM6E 2NUEA 2R3AA 4DV6E 2V83A 1YYKA 5A2QC 2GLIA 1TF3A 1AAYA 1MVXA 1YZ9A 4JI2E 1A1FA 2V88A 2EN2A 1T4OA 2EN7A 5BR8E 4R8OA 4B3SE 1HNXE 4JYAE 4NVQA 5KL6A 1MT6A 1ZBTA 2L33A 4IJ8A 5AE2A 1N34E 3OOIA 2K7IA 3EPLA 1ZBQA 3UK3C 2WBTA 5KL3A 4J7IA 1PKPA 2EMHA 2F4VE 1J26A 4NXNE 1B69A 2L8TA 2VF1A 3C6MA 5LLQA 2QPWA 2JV0A 1F2IG 2YPNA 2B9DA 2EOMA 1DQ3A 1MGTA 4DR3E 5ARGA 3DB5A 4QEOA 1UN6B 1UILA 2L92A 5EG2A 3ADGA 2M1SA 2RPCA 2DIXA 2EM4A 2YSPA 5LL6R 5KL7A 3M55A 4JI4E 2ODRD 1YUJA 1X47A 5IV8B 2M7QA 3FPDA 1O0WA 4JI7E 2CTDA 2EM0A 5EX0A 4M9VC 2NABA 2EPRA 1X6HA 5JINA 2YTIA 3IWCA 4NXME 3EPHA 3EP0A 3QWWA 2EPKX 3KMAA 4WSPA 2LTSA 4HTGA 1A1HA 4BCAA 4YNMA 5KJMA 2EN3A 2RFIA 2YWQA 1IQSA 4MLQA 2NA2A 2VE7C 2DSYA 2UXCE 2M9AA 4LFAE 1IQOA 4JLGA 5CFFE 4BBYA 4LF7E 3ADIA 5CCLA 4LF5E 5KL4A 4H12A 3F9YA 2YRMA 2EOSA 1X48A 2EP3A 3P1XA 1RC7A 4BHCA 4WSGA 3L00A 2HC5A 2LUQA 3TQMA 2GPIA 1N3JA 1MUFA 1RMDA 4GKJE 2V86A 5AE3A 2F8BA 4YNPA 3TG4A 4ZYDA 1DI2A 2VQEE 4ZYGA 1HNZE 3C6KA 2ODRC 3IHXA 3JAMC 4DUZE 1A1KA 2EN1A 5KL5A 5F6LA 4O6FA 2EPUA 3VUZA 3RMPA 4GEQB 2JOBA 2LVHA 4BC7A 4DV0E 1PJSA 4NHRA 2ELYA 2YTEA 3TG5A 2ENCA 1MEYC 4Q28A 3DF6A 5T6JA 2WBUA 2FTXB 4LFBE 2EOXA 4YPUA 4LTYA 2UXDE 3S7JA 5LSZA 3T1YE 1N6AA 3C4BA 3SW9A 2EMZA 1H3IA 4JI8E 4BMJA 4R2AA 3DJWA 4F2JC 2YTJA 2WBSA 4O30A 1WRJA 4R2CA 4DR6E 4X66E 2DRPA 3KMJA 4LF8E 2EQ1A 4LF6E 4B3RE 4NJ5A 3VK6A 3J80C 2UUAE 3K5KA 3HPZA 4P78A 3F6HA 2EM7A 5KJLA 3MHSC 4DV7E 2JYAA 4F9CB 5A6BD 3AV0A 2EPOA 4RH8A 2B3TB 1EKZA 2YTQA 2V87A 2EOOA 1GZ6A 4X62E 2EOYA 2YRKA 4OOGC 5F59A 3HNAA 4F9BB 4DMIA 5A6KA 4WX9A 5AYFA 2N8XA 5T5GA 3F9ZA 1PDAA 1X49A 2UXBE 2D9HA 2EPZA 2EMXA 4J83A 3J7Yp 1T39A 3MO0A 2L2KB 3RQ4A 5DNYA 2MKNA 5EX3A 1YYOA 2EORA 2RS6A 1QNTA 4DV3E 5TSEA 1MVHA 1IBME 4WXDA 4DR4E 1JK1A 5AC4A 2EOQA 3BF2A 2N3GA 2RS7A 1BBOA 2G7HA 2JXPA 4DV1E 4LDGA 3M57A 3EPKA 5KL2A 2LTRA 4RZ0A 5LMNE 2ENAA 2EOHA 2EPNA 2JVAA 2LMZA 2WZOA 4IJDA 1WJPA 5A6BA 1X5WA 4DV5E 2YSOA 5JHNA 1HNWE 4JDSA 4MI5A 2V85A 5HQ8A 1HR0E 2CSHA 4DUYE 4GZNC 3EQ1A 1X3CA 2RQLA 4BHBA 2EMYA 4J8OA 3THOB 3N71A 3OMLA 1IBLE 3S8PA 4O5GA 4BS9A 2EPPA 3BO5A 3VHTB 2I13A 4F9AB 3KMTA 1DGCA 2E5LE 3MEKA 1G2DC 2LJHA 2JR1A 3CBPA 3KZZA 2HGHA 1XNQE 1XMQE 2Q8UA 3CBMA 1X6EA 1GQEA 1T38A 3T1HE 2JOXA 2DLQA 3BGHA 3C4TA 2PRTA 5CCMA 2LO3A 2LCEA 2EM8A 1N6CA 4F6NA 2EM3A 2NUFA 4P7DA 3ADJA 3JTZA 2V8QB 4L5NC 2JWOA 2R76A 4YPEA 2VRDA 2UU9E 2LJUA 4K0KE 4O43A 5KJKA 2EMLA 1LLMC 1BB8A 1A1LA 4DR7E 2EL4A 4C1QA 2I9IA 4YNDA 4TUGA 4DR2E 5IT9C 1T4LB 5IXMB 2N3HA 1L4SA 1ML9A 1WHQA 3BBGA 5AC5A 2EMKA 2L2NA 4KHPE 2JP9A 3OTOE 4GKKE 1GTKA 2EPAA 2YTFA 1UHZA 4X9JA 4JV5E 3MSWA 4BUPA 2EOEA 1BBGA 2EJ4A 2EM5A 2L3CA 4DR5E 3J81C 1J5EE 4F54A 4IS1C 4HEIA 2E72A 4M0VA 2KOUA 4JI6E 4MLVA 4I8OA 2UUBE 3FIGA 2YZTA 3M5AA 2CT1A 2YT4A 2W5ZA 2ADRA 1YUIA 2E1MA 1NCSA 2EM9A 4JI0E 2YTNA 2EE8A 1TF6A 5F3WA 4QEPA 4DV4E 4WUYA 2VQFE 5F6KC 4B3TE 2CPNA 4WPYA 2WCC3 5JIYA 4R2QA 3RAYA 1FJGE 2LT7A 1XNRE 3DALA 2LRSA 2LBSB 4JI5E 1WHNA 3VYYA 1STUA 2O8JA 3HPSA 2MDRA 2RSIA 2YU8A 1ZR9A 4R2DA 1QU6A 2B7TA 3EPJA 2FV4B 5CPRB 3KWRA 2K4VA 3BIDA 1XQHA 1A1IA 1KYQA 3M53A 4QENA 2YU5A 2J7JA 3IWBA 2BBGA 2M4IA 4M30A 4R03A 2MC5A 1PEGA 1SR9A 3RU0A 3IWDA 2DLKA 2W5YA 2L6MA 2EOZA 4O4KA 1SFEA 4L8NA 5LSXA 2KONA 2KHXA 3J7AG 2EN6A 3THNA 5ADZA 3M56A 3LLHA 3OXFA 3MO5A 1X6FA 4R2SA 4WFTA 2DMIA 5TH7A 4OX9E 1RQ0A 2ENHA 4TUIA 1WXRA 4DV2E 2HHHE 3JU0A 1TN9A 2G46A 1A1GA 1IMUA 2EPMX 3CBOA 3HQ1A 5LMUE 2NUGA 4B3ME 2EN8A 2ELZA 2EOFA 4WXCA 1I94E 3MHHC 5AASA 3F6GA 1UBDC 4WYQB 1FKAE 2EQ3A 4JI1E 4JI3E 2EN4A 4M2ZA 2YTOA 1ZAAC 4E47A 1ZU1A 3ADLA 4I51A 3SWCA 4X64E 2EPCA 2DGCA 3HXLA 4X8WA 3OPEA 2H36X 2EQ0A 4KWYA 3S7BA 1EH6A 1N33E 5A6JA 4Q35B 3OXGA 5KJNA 4AQYE 2JY9A 5ARFA 2HJJA 2EMIA 4ZYHA 4KZSA 4BC9A 3M59A 4O24A 2EMCA 2EMAA 5AE1A 3OXLA 2RTXA 2YTPA 3QWVA 4DKKA 2EWLA 1IBKE 1Z1BA 1KJKA 5TEGA 2LV2A 3M58A 2GHFA 2YTDA 3M99B 5T0KA 2JPAA 1EH8A 5TTFA 2L2MA 4Z4PA 1XMOE 1YSAC 1AH5A 2EOIA 3KZYA 2LUPB 1P47A 4AU7A 3F9WA 5A69A 2MDGA 1YYWA 2B7VA 3VYXA 4F6MA 1T4NA 2EMFA 3RJWA 1PJTA 4J7FA 2FGGA 4ZYEA 4MI0A 2BQZA 1YFHA 1N36E 2MC6A 4RHBB 4R2RA 1PJQA 5A6AA 3VV0A 4X65E
chains in the Genus database with same CATH topology
2YTGA 3S7DA 1ZKKA 2F69A 2EL5A 2A25A 2EMWA 2EMBA 2EMGA 4FMUA 2EPXA 4YPAA 2IGQA 1G2FC 3QWPA 2EM6A 2EOJA 3MO2A 5HI7A 2R1FA 3RIBA 5F5EA 2MKDA 3OS5A 3M54A 2EM2A 4FK5C 3PDNA 4R2EA 5JJ0A 4R2PA 2BB8A 1A1JA 1JK2A 1O9SA 5T0MA 2YRHA 2EL6A 3F9XA 3S7FA 2R3AA 2GLIA 1TF3A 1AAYA 1MVXA 1A1FA 2EN2A 2EN7A 4NVQA 5KL6A 1MT6A 4IJ8A 3OOIA 3EPLA 3UK3C 2WBTA 5KL3A 4J7IA 2EMHA 1B69A 2QPWA 2JV0A 1F2IG 2EOMA 5ARGA 3DB5A 4QEOA 1UN6B 5EG2A 2RPCA 2EM4A 2YSPA 5KL7A 3M55A 1YUJA 3FPDA 2CTDA 2EM0A 5EX0A 4M9VC 2NABA 2EPRA 1X6HA 5JINA 2YTIA 3EPHA 3EP0A 3QWWA 3KMAA 1A1HA 4YNMA 5KJMA 2EN3A 2RFIA 2M9AA 4JLGA 5CCLA 5KL4A 4H12A 3F9YA 2YRMA 2EOSA 2EP3A 4WSGA 1N3JA 1MUFA 1RMDA 4YNPA 3TG4A 3IHXA 1A1KA 2EN1A 5KL5A 5F6LA 4O6FA 2EPUA 3VUZA 2LVHA 2ELYA 2YTEA 3TG5A 2ENCA 1MEYC 2WBUA 2EOXA 4YPUA 3S7JA 5LSZA 1N6AA 3SW9A 2EMZA 1H3IA 4R2AA 4F2JC 2YTJA 2WBSA 4O30A 4R2CA 2DRPA 3KMJA 2EQ1A 4NJ5A 3K5KA 2EM7A 5KJLA 3MHSC 2YTQA 2EOOA 2EOYA 2YRKA 5F59A 3HNAA 5AYFA 5T5GA 3F9ZA 2D9HA 2EPZA 2EMXA 4J83A 3MO0A 3RQ4A 2MKNA 5EX3A 2EORA 1MVHA 1JK1A 2EOQA 1BBOA 4LDGA 3M57A 3EPKA 5KL2A 4RZ0A 2ENAA 2EOHA 4IJDA 1WJPA 1X5WA 2YSOA 5JHNA 4JDSA 4MI5A 5HQ8A 2CSHA 4GZNC 1X3CA 2EMYA 4J8OA 3N71A 3S8PA 2EPPA 3BO5A 3VHTB 2I13A 1DGCA 3KMTA 3MEKA 1G2DC 3CBPA 2HGHA 3CBMA 1X6EA 2DLQA 2PRTA 5CCMA 2LO3A 2LCEA 2EM8A 1N6CA 4F6NA 2EM3A 4YPEA 2VRDA 5KJKA 2EMLA 1LLMC 1BB8A 1A1LA 2EL4A 4C1QA 4YNDA 1ML9A 2EMKA 2JP9A 2EPAA 2YTFA 4X9JA 4BUPA 2EOEA 2EJ4A 2EM5A 4IS1C 2E72A 3M5AA 2CT1A 2W5ZA 2ADRA 1YUIA 1NCSA 2EM9A 2YTNA 2EE8A 1TF6A 4QEPA 4WUYA 5F6KC 2WCC3 5JIYA 4R2QA 3RAYA 2LT7A 3DALA 2O8JA 2RSIA 2YU8A 1ZR9A 4R2DA 3EPJA 5CPRB 1XQHA 1A1IA 3M53A 4QENA 2YU5A 2J7JA 1PEGA 3RU0A 2DLKA 2W5YA 2EOZA 5LSXA 2EN6A 3M56A 3OXFA 3MO5A 1X6FA 4R2SA 2DMIA 5TH7A 2ENHA 1TN9A 2G46A 1A1GA 3CBOA 2EN8A 2ELZA 2EOFA 3MHHC 1UBDC 2EQ3A 2EN4A 2YTOA 1ZAAC 4E47A 1ZU1A 4I51A 3SWCA 2EPCA 2DGCA 3OPEA 2EQ0A 3S7BA 3OXGA 5KJNA 5ARFA 2EMIA 3M59A 2EMCA 2EMAA 3OXLA 2YTPA 3QWVA 1Z1BA 1KJKA 5TEGA 2LV2A 3M58A 2GHFA 2YTDA 3M99B 5T0KA 2JPAA 5TTFA 4Z4PA 1YSAC 2EOIA 1P47A 4AU7A 3F9WA 2MDGA 4F6MA 2EMFA 3RJWA 4J7FA 4MI0A 2BQZA 4R2RA 3VV0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YTG A;  3S7D A;  1ZKK A;  2F69 A;  2EL5 A;  2A25 A;  2EMW A;  2EMB A;  2EMG A;  4FMU A;  2EPX A;  4YPA A;  2IGQ A;  1G2F C;  3QWP A;  2EM6 A;  2EOJ A;  3MO2 A;  5HI7 A;  2R1F A;  3RIB A;  5F5E A;  2MKD A;  3OS5 A;  3M54 A;  2EM2 A;  4FK5 C;  3PDN A;  4R2E A;  5JJ0 A;  4R2P A;  2BB8 A;  1A1J A;  1JK2 A;  1O9S A;  5T0M A;  2YRH A;  2EL6 A;  3F9X A;  3S7F A;  2R3A A;  2GLI A;  1TF3 A;  1AAY A;  1MVX A;  1A1F A;  2EN2 A;  2EN7 A;  4NVQ A;  5KL6 A;  1MT6 A;  4IJ8 A;  3OOI A;  3EPL A;  3UK3 C;  2WBT A;  5KL3 A;  4J7I A;  2EMH A;  1B69 A;  2QPW A;  2JV0 A;  1F2I G;  2EOM A;  5ARG A;  3DB5 A;  4QEO A;  1UN6 B;  5EG2 A;  2RPC A;  2EM4 A;  2YSP A;  5KL7 A;  3M55 A;  1YUJ A;  3FPD A;  2CTD A;  2EM0 A;  5EX0 A;  4M9V C;  2NAB A;  2EPR A;  1X6H A;  5JIN A;  2YTI A;  3EPH A;  3EP0 A;  3QWW A;  3KMA A;  1A1H A;  4YNM A;  5KJM A;  2EN3 A;  2RFI A;  2M9A A;  4JLG A;  5CCL A;  5KL4 A;  4H12 A;  3F9Y A;  2YRM A;  2EOS A;  2EP3 A;  4WSG A;  1N3J A;  1MUF A;  1RMD A;  4YNP A;  3TG4 A;  3IHX A;  1A1K A;  2EN1 A;  5KL5 A;  5F6L A;  4O6F A;  2EPU A;  3VUZ A;  2LVH A;  2ELY A;  2YTE A;  3TG5 A;  2ENC A;  1MEY C;  2WBU A;  2EOX A;  4YPU A;  3S7J A;  5LSZ A;  1N6A A;  3SW9 A;  2EMZ A;  1H3I A;  4R2A A;  4F2J C;  2YTJ A;  2WBS A;  4O30 A;  4R2C A;  2DRP A;  3KMJ A;  2EQ1 A;  4NJ5 A;  3K5K A;  2EM7 A;  5KJL A;  3MHS C;  2YTQ A;  2EOO A;  2EOY A;  2YRK A;  5F59 A;  3HNA A;  5AYF A;  5T5G A;  3F9Z A;  2D9H A;  2EPZ A;  2EMX A;  4J83 A;  3MO0 A;  3RQ4 A;  2MKN A;  5EX3 A;  2EOR A;  1MVH A;  1JK1 A;  2EOQ A;  1BBO A;  4LDG A;  3M57 A;  3EPK A;  5KL2 A;  4RZ0 A;  2ENA A;  2EOH A;  4IJD A;  1WJP A;  1X5W A;  2YSO A;  5JHN A;  4JDS A;  4MI5 A;  5HQ8 A;  2CSH A;  4GZN C;  1X3C A;  2EMY A;  4J8O A;  3N71 A;  3S8P A;  2EPP A;  3BO5 A;  3VHT B;  2I13 A;  1DGC A;  3KMT A;  3MEK A;  1G2D C;  3CBP A;  2HGH A;  3CBM A;  1X6E A;  2DLQ A;  2PRT A;  5CCM A;  2LO3 A;  2LCE A;  2EM8 A;  1N6C A;  4F6N A;  2EM3 A;  4YPE A;  2VRD A;  5KJK A;  2EML A;  1LLM C;  1BB8 A;  1A1L A;  2EL4 A;  4C1Q A;  4YND A;  1ML9 A;  2EMK A;  2JP9 A;  2EPA A;  2YTF A;  4X9J A;  4BUP A;  2EOE A;  2EJ4 A;  2EM5 A;  4IS1 C;  2E72 A;  3M5A A;  2CT1 A;  2W5Z A;  2ADR A;  1YUI A;  1NCS A;  2EM9 A;  2YTN A;  2EE8 A;  1TF6 A;  4QEP A;  4WUY A;  5F6K C;  2WCC 3;  5JIY A;  4R2Q A;  3RAY A;  2LT7 A;  3DAL A;  2O8J A;  2RSI A;  2YU8 A;  1ZR9 A;  4R2D A;  3EPJ A;  5CPR B;  1XQH A;  1A1I A;  3M53 A;  4QEN A;  2YU5 A;  2J7J A;  1PEG A;  3RU0 A;  2DLK A;  2W5Y A;  2EOZ A;  5LSX A;  2EN6 A;  3M56 A;  3OXF A;  3MO5 A;  1X6F A;  4R2S A;  2DMI A;  5TH7 A;  2ENH A;  1TN9 A;  2G46 A;  1A1G A;  3CBO A;  2EN8 A;  2ELZ A;  2EOF A;  3MHH C;  1UBD C;  2EQ3 A;  2EN4 A;  2YTO A;  1ZAA C;  4E47 A;  1ZU1 A;  4I51 A;  3SWC A;  2EPC A;  2DGC A;  3OPE A;  2EQ0 A;  3S7B A;  3OXG A;  5KJN A;  5ARF A;  2EMI A;  3M59 A;  2EMC A;  2EMA A;  3OXL A;  2YTP A;  3QWV A;  1Z1B A;  1KJK A;  5TEG A;  2LV2 A;  3M58 A;  2GHF A;  2YTD A;  3M99 B;  5T0K A;  2JPA A;  5TTF A;  4Z4P A;  1YSA C;  2EOI A;  1P47 A;  4AU7 A;  3F9W A;  2MDG A;  4F6M A;  2EMF A;  3RJW A;  4J7F A;  4MI0 A;  2BQZ A;  4R2R A;  3VV0 A; 
#chains in the Genus database with same CATH topology
 2YTG A;  3H09 A;  3S7D A;  1ZKK A;  2F69 A;  2RSM A;  1N32 E;  4J8Z A;  2EL5 A;  3AUZ A;  2UUC E;  2A25 A;  1NEI A;  2EMW A;  2EMB A;  2EMG A;  3K6Q A;  2EZ6 A;  3HTX A;  4LU9 A;  2L3J A;  4YY3 E;  4FMU A;  2EPX A;  2DMY A;  4YPA A;  2IGQ A;  5IWA E;  4YHH E;  1G2F C;  3QWP A;  2EM6 A;  2EOJ A;  3MO2 A;  5HI7 A;  1YPN A;  2R1F A;  2V89 A;  3RIB A;  1N3G A;  5F5E A;  2MKD A;  4LFC E;  3OS5 A;  4N4R B;  2EPL X;  3M54 A;  2EM2 A;  3ZOQ B;  4FK5 C;  3PDN A;  1EH7 A;  4R2E A;  4LF4 E;  3ECR A;  5JJ0 A;  2DB2 A;  3QG5 C;  4R2P A;  2BB8 A;  1A1J A;  4NZV A;  1JK2 A;  1O9S A;  5T0M A;  4DR1 E;  2IHR 1;  2LE2 A;  4LF9 E;  2YRH A;  2EL6 A;  5FLX C;  3F9X A;  3S7F A;  3LML A;  2ZM6 E;  2NUE A;  2R3A A;  4DV6 E;  2V83 A;  1YYK A;  5A2Q C;  2GLI A;  1TF3 A;  1AAY A;  1MVX A;  1YZ9 A;  4JI2 E;  1A1F A;  2V88 A;  2EN2 A;  1T4O A;  2EN7 A;  5BR8 E;  4R8O A;  4B3S E;  1HNX E;  4JYA E;  4NVQ A;  5KL6 A;  1MT6 A;  1ZBT A;  2L33 A;  4IJ8 A;  5AE2 A;  1N34 E;  3OOI A;  2K7I A;  3EPL A;  1ZBQ A;  3UK3 C;  2WBT A;  5KL3 A;  4J7I A;  1PKP A;  2EMH A;  2F4V E;  1J26 A;  4NXN E;  1B69 A;  2L8T A;  2VF1 A;  3C6M A;  5LLQ A;  2QPW A;  2JV0 A;  1F2I G;  2YPN A;  2B9D A;  2EOM A;  1DQ3 A;  1MGT A;  4DR3 E;  5ARG A;  3DB5 A;  4QEO A;  1UN6 B;  1UIL A;  2L92 A;  5EG2 A;  3ADG A;  2M1S A;  2RPC A;  2DIX A;  2EM4 A;  2YSP A;  5LL6 R;  5KL7 A;  3M55 A;  4JI4 E;  2ODR D;  1YUJ A;  1X47 A;  5IV8 B;  2M7Q A;  3FPD A;  1O0W A;  4JI7 E;  2CTD A;  2EM0 A;  5EX0 A;  4M9V C;  2NAB A;  2EPR A;  1X6H A;  5JIN A;  2YTI A;  3IWC A;  4NXM E;  3EPH A;  3EP0 A;  3QWW A;  2EPK X;  3KMA A;  4WSP A;  2LTS A;  4HTG A;  1A1H A;  4BCA A;  4YNM A;  5KJM A;  2EN3 A;  2RFI A;  2YWQ A;  1IQS A;  4MLQ A;  2NA2 A;  2VE7 C;  2DSY A;  2UXC E;  2M9A A;  4LFA E;  1IQO A;  4JLG A;  5CFF E;  4BBY A;  4LF7 E;  3ADI A;  5CCL A;  4LF5 E;  5KL4 A;  4H12 A;  3F9Y A;  2YRM A;  2EOS A;  1X48 A;  2EP3 A;  3P1X A;  1RC7 A;  4BHC A;  4WSG A;  3L00 A;  2HC5 A;  2LUQ A;  3TQM A;  2GPI A;  1N3J A;  1MUF A;  1RMD A;  4GKJ E;  2V86 A;  5AE3 A;  2F8B A;  4YNP A;  3TG4 A;  4ZYD A;  1DI2 A;  2VQE E;  4ZYG A;  1HNZ E;  3C6K A;  2ODR C;  3IHX A;  3JAM C;  4DUZ E;  1A1K A;  2EN1 A;  5KL5 A;  5F6L A;  4O6F A;  2EPU A;  3VUZ A;  3RMP A;  4GEQ B;  2JOB A;  2LVH A;  4BC7 A;  4DV0 E;  1PJS A;  4NHR A;  2ELY A;  2YTE A;  3TG5 A;  2ENC A;  1MEY C;  4Q28 A;  3DF6 A;  5T6J A;  2WBU A;  2FTX B;  4LFB E;  2EOX A;  4YPU A;  4LTY A;  2UXD E;  3S7J A;  5LSZ A;  3T1Y E;  1N6A A;  3C4B A;  3SW9 A;  2EMZ A;  1H3I A;  4JI8 E;  4BMJ A;  4R2A A;  3DJW A;  4F2J C;  2YTJ A;  2WBS A;  4O30 A;  1WRJ A;  4R2C A;  4DR6 E;  4X66 E;  2DRP A;  3KMJ A;  4LF8 E;  2EQ1 A;  4LF6 E;  4B3R E;  4NJ5 A;  3VK6 A;  3J80 C;  2UUA E;  3K5K A;  3HPZ A;  4P78 A;  3F6H A;  2EM7 A;  5KJL A;  3MHS C;  4DV7 E;  2JYA A;  4F9C B;  5A6B D;  3AV0 A;  2EPO A;  4RH8 A;  2B3T B;  1EKZ A;  2YTQ A;  2V87 A;  2EOO A;  1GZ6 A;  4X62 E;  2EOY A;  2YRK A;  4OOG C;  5F59 A;  3HNA A;  4F9B B;  4DMI A;  5A6K A;  4WX9 A;  5AYF A;  2N8X A;  5T5G A;  3F9Z A;  1PDA A;  1X49 A;  2UXB E;  2D9H A;  2EPZ A;  2EMX A;  4J83 A;  3J7Y p;  1T39 A;  3MO0 A;  2L2K B;  3RQ4 A;  5DNY A;  2MKN A;  5EX3 A;  1YYO A;  2EOR A;  2RS6 A;  1QNT A;  4DV3 E;  5TSE A;  1MVH A;  1IBM E;  4WXD A;  4DR4 E;  1JK1 A;  5AC4 A;  2EOQ A;  3BF2 A;  2N3G A;  2RS7 A;  1BBO A;  2G7H A;  2JXP A;  4DV1 E;  4LDG A;  3M57 A;  3EPK A;  5KL2 A;  2LTR A;  4RZ0 A;  5LMN E;  2ENA A;  2EOH A;  2EPN A;  2JVA A;  2LMZ A;  2WZO A;  4IJD A;  1WJP A;  5A6B A;  1X5W A;  4DV5 E;  2YSO A;  5JHN A;  1HNW E;  4JDS A;  4MI5 A;  2V85 A;  5HQ8 A;  1HR0 E;  2CSH A;  4DUY E;  4GZN C;  3EQ1 A;  1X3C A;  2RQL A;  4BHB A;  2EMY A;  4J8O A;  3THO B;  3N71 A;  3OML A;  1IBL E;  3S8P A;  4O5G A;  4BS9 A;  2EPP A;  3BO5 A;  3VHT B;  2I13 A;  4F9A B;  3KMT A;  1DGC A;  2E5L E;  3MEK A;  1G2D C;  2LJH A;  2JR1 A;  3CBP A;  3KZZ A;  2HGH A;  1XNQ E;  1XMQ E;  2Q8U A;  3CBM A;  1X6E A;  1GQE A;  1T38 A;  3T1H E;  2JOX A;  2DLQ A;  3BGH A;  3C4T A;  2PRT A;  5CCM A;  2LO3 A;  2LCE A;  2EM8 A;  1N6C A;  4F6N A;  2EM3 A;  2NUF A;  4P7D A;  3ADJ A;  3JTZ A;  2V8Q B;  4L5N C;  2JWO A;  2R76 A;  4YPE A;  2VRD A;  2UU9 E;  2LJU A;  4K0K E;  4O43 A;  5KJK A;  2EML A;  1LLM C;  1BB8 A;  1A1L A;  4DR7 E;  2EL4 A;  4C1Q A;  2I9I A;  4YND A;  4TUG A;  4DR2 E;  5IT9 C;  1T4L B;  5IXM B;  2N3H A;  1L4S A;  1ML9 A;  1WHQ A;  3BBG A;  5AC5 A;  2EMK A;  2L2N A;  4KHP E;  2JP9 A;  3OTO E;  4GKK E;  1GTK A;  2EPA A;  2YTF A;  1UHZ A;  4X9J A;  4JV5 E;  3MSW A;  4BUP A;  2EOE A;  1BBG A;  2EJ4 A;  2EM5 A;  2L3C A;  4DR5 E;  3J81 C;  1J5E E;  4F54 A;  4IS1 C;  4HEI A;  2E72 A;  4M0V A;  2KOU A;  4JI6 E;  4MLV A;  4I8O A;  2UUB E;  3FIG A;  2YZT A;  3M5A A;  2CT1 A;  2YT4 A;  2W5Z A;  2ADR A;  1YUI A;  2E1M A;  1NCS A;  2EM9 A;  4JI0 E;  2YTN A;  2EE8 A;  1TF6 A;  5F3W A;  4QEP A;  4DV4 E;  4WUY A;  2VQF E;  5F6K C;  4B3T E;  2CPN A;  4WPY A;  2WCC 3;  5JIY A;  4R2Q A;  3RAY A;  1FJG E;  2LT7 A;  1XNR E;  3DAL A;  2LRS A;  2LBS B;  4JI5 E;  1WHN A;  3VYY A;  1STU A;  2O8J A;  3HPS A;  2MDR A;  2RSI A;  2YU8 A;  1ZR9 A;  4R2D A;  1QU6 A;  2B7T A;  3EPJ A;  2FV4 B;  5CPR B;  3KWR A;  2K4V A;  3BID A;  1XQH A;  1A1I A;  1KYQ A;  3M53 A;  4QEN A;  2YU5 A;  2J7J A;  3IWB A;  2BBG A;  2M4I A;  4M30 A;  4R03 A;  2MC5 A;  1PEG A;  1SR9 A;  3RU0 A;  3IWD A;  2DLK A;  2W5Y A;  2L6M A;  2EOZ A;  4O4K A;  1SFE A;  4L8N A;  5LSX A;  2KON A;  2KHX A;  3J7A G;  2EN6 A;  3THN A;  5ADZ A;  3M56 A;  3LLH A;  3OXF A;  3MO5 A;  1X6F A;  4R2S A;  4WFT A;  2DMI A;  5TH7 A;  4OX9 E;  1RQ0 A;  2ENH A;  4TUI A;  1WXR A;  4DV2 E;  2HHH E;  3JU0 A;  1TN9 A;  2G46 A;  1A1G A;  1IMU A;  2EPM X;  3CBO A;  3HQ1 A;  5LMU E;  2NUG A;  4B3M E;  2EN8 A;  2ELZ A;  2EOF A;  4WXC A;  1I94 E;  3MHH C;  5AAS A;  3F6G A;  1UBD C;  4WYQ B;  1FKA E;  2EQ3 A;  4JI1 E;  4JI3 E;  2EN4 A;  4M2Z A;  2YTO A;  1ZAA C;  4E47 A;  1ZU1 A;  3ADL A;  4I51 A;  3SWC A;  4X64 E;  2EPC A;  2DGC A;  3HXL A;  4X8W A;  3OPE A;  2H36 X;  2EQ0 A;  4KWY A;  3S7B A;  1EH6 A;  1N33 E;  5A6J A;  4Q35 B;  3OXG A;  5KJN A;  4AQY E;  2JY9 A;  5ARF A;  2HJJ A;  2EMI A;  4ZYH A;  4KZS A;  4BC9 A;  3M59 A;  4O24 A;  2EMC A;  2EMA A;  5AE1 A;  3OXL A;  2RTX A;  2YTP A;  3QWV A;  4DKK A;  2EWL A;  1IBK E;  1Z1B A;  1KJK A;  5TEG A;  2LV2 A;  3M58 A;  2GHF A;  2YTD A;  3M99 B;  5T0K A;  2JPA A;  1EH8 A;  5TTF A;  2L2M A;  4Z4P A;  1XMO E;  1YSA C;  1AH5 A;  2EOI A;  3KZY A;  2LUP B;  1P47 A;  4AU7 A;  3F9W A;  5A69 A;  2MDG A;  1YYW A;  2B7V A;  3VYX A;  4F6M A;  1T4N A;  2EMF A;  3RJW A;  1PJT A;  4J7F A;  2FGG A;  4ZYE A;  4MI0 A;  2BQZ A;  1YFH A;  1N36 E;  2MC6 A;  4RHB B;  4R2R A;  1PJQ A;  5A6A A;  3VV0 A;  4X65 E; 
#chains in the Genus database with same CATH homology
 2YTG A;  3S7D A;  1ZKK A;  2F69 A;  2EL5 A;  2A25 A;  2EMW A;  2EMB A;  2EMG A;  4FMU A;  2EPX A;  4YPA A;  2IGQ A;  1G2F C;  3QWP A;  2EM6 A;  2EOJ A;  3MO2 A;  5HI7 A;  2R1F A;  3RIB A;  5F5E A;  2MKD A;  3OS5 A;  3M54 A;  2EM2 A;  4FK5 C;  3PDN A;  4R2E A;  5JJ0 A;  4R2P A;  2BB8 A;  1A1J A;  1JK2 A;  1O9S A;  5T0M A;  2YRH A;  2EL6 A;  3F9X A;  3S7F A;  2R3A A;  2GLI A;  1TF3 A;  1AAY A;  1MVX A;  1A1F A;  2EN2 A;  2EN7 A;  4NVQ A;  5KL6 A;  1MT6 A;  4IJ8 A;  3OOI A;  3EPL A;  3UK3 C;  2WBT A;  5KL3 A;  4J7I A;  2EMH A;  1B69 A;  2QPW A;  2JV0 A;  1F2I G;  2EOM A;  5ARG A;  3DB5 A;  4QEO A;  1UN6 B;  5EG2 A;  2RPC A;  2EM4 A;  2YSP A;  5KL7 A;  3M55 A;  1YUJ A;  3FPD A;  2CTD A;  2EM0 A;  5EX0 A;  4M9V C;  2NAB A;  2EPR A;  1X6H A;  5JIN A;  2YTI A;  3EPH A;  3EP0 A;  3QWW A;  3KMA A;  1A1H A;  4YNM A;  5KJM A;  2EN3 A;  2RFI A;  2M9A A;  4JLG A;  5CCL A;  5KL4 A;  4H12 A;  3F9Y A;  2YRM A;  2EOS A;  2EP3 A;  4WSG A;  1N3J A;  1MUF A;  1RMD A;  4YNP A;  3TG4 A;  3IHX A;  1A1K A;  2EN1 A;  5KL5 A;  5F6L A;  4O6F A;  2EPU A;  3VUZ A;  2LVH A;  2ELY A;  2YTE A;  3TG5 A;  2ENC A;  1MEY C;  2WBU A;  2EOX A;  4YPU A;  3S7J A;  5LSZ A;  1N6A A;  3SW9 A;  2EMZ A;  1H3I A;  4R2A A;  4F2J C;  2YTJ A;  2WBS A;  4O30 A;  4R2C A;  2DRP A;  3KMJ A;  2EQ1 A;  4NJ5 A;  3K5K A;  2EM7 A;  5KJL A;  3MHS C;  2YTQ A;  2EOO A;  2EOY A;  2YRK A;  5F59 A;  3HNA A;  5AYF A;  5T5G A;  3F9Z A;  2D9H A;  2EPZ A;  2EMX A;  4J83 A;  3MO0 A;  3RQ4 A;  2MKN A;  5EX3 A;  2EOR A;  1MVH A;  1JK1 A;  2EOQ A;  1BBO A;  4LDG A;  3M57 A;  3EPK A;  5KL2 A;  4RZ0 A;  2ENA A;  2EOH A;  4IJD A;  1WJP A;  1X5W A;  2YSO A;  5JHN A;  4JDS A;  4MI5 A;  5HQ8 A;  2CSH A;  4GZN C;  1X3C A;  2EMY A;  4J8O A;  3N71 A;  3S8P A;  2EPP A;  3BO5 A;  3VHT B;  2I13 A;  1DGC A;  3KMT A;  3MEK A;  1G2D C;  3CBP A;  2HGH A;  3CBM A;  1X6E A;  2DLQ A;  2PRT A;  5CCM A;  2LO3 A;  2LCE A;  2EM8 A;  1N6C A;  4F6N A;  2EM3 A;  4YPE A;  2VRD A;  5KJK A;  2EML A;  1LLM C;  1BB8 A;  1A1L A;  2EL4 A;  4C1Q A;  4YND A;  1ML9 A;  2EMK A;  2JP9 A;  2EPA A;  2YTF A;  4X9J A;  4BUP A;  2EOE A;  2EJ4 A;  2EM5 A;  4IS1 C;  2E72 A;  3M5A A;  2CT1 A;  2W5Z A;  2ADR A;  1YUI A;  1NCS A;  2EM9 A;  2YTN A;  2EE8 A;  1TF6 A;  4QEP A;  4WUY A;  5F6K C;  2WCC 3;  5JIY A;  4R2Q A;  3RAY A;  2LT7 A;  3DAL A;  2O8J A;  2RSI A;  2YU8 A;  1ZR9 A;  4R2D A;  3EPJ A;  5CPR B;  1XQH A;  1A1I A;  3M53 A;  4QEN A;  2YU5 A;  2J7J A;  1PEG A;  3RU0 A;  2DLK A;  2W5Y A;  2EOZ A;  5LSX A;  2EN6 A;  3M56 A;  3OXF A;  3MO5 A;  1X6F A;  4R2S A;  2DMI A;  5TH7 A;  2ENH A;  1TN9 A;  2G46 A;  1A1G A;  3CBO A;  2EN8 A;  2ELZ A;  2EOF A;  3MHH C;  1UBD C;  2EQ3 A;  2EN4 A;  2YTO A;  1ZAA C;  4E47 A;  1ZU1 A;  4I51 A;  3SWC A;  2EPC A;  2DGC A;  3OPE A;  2EQ0 A;  3S7B A;  3OXG A;  5KJN A;  5ARF A;  2EMI A;  3M59 A;  2EMC A;  2EMA A;  3OXL A;  2YTP A;  3QWV A;  1Z1B A;  1KJK A;  5TEG A;  2LV2 A;  3M58 A;  2GHF A;  2YTD A;  3M99 B;  5T0K A;  2JPA A;  5TTF A;  4Z4P A;  1YSA C;  2EOI A;  1P47 A;  4AU7 A;  3F9W A;  2MDG A;  4F6M A;  2EMF A;  3RJW A;  4J7F A;  4MI0 A;  2BQZ A;  4R2R A;  3VV0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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