4INBA

Crystal structure of the n-terminal domain of hiv-1 capsid in complex with benzodiazepine inhibitor
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monitoring Binding of HIV-1 Capsid Assembly Inhibitors Using (19) F Ligand-and (15) N Protein-Based NMR and X-ray Crystallography: Early Hit Validation of a Benzodiazepine Series.
pubmed doi rcsb
molecule tags Viral protein/viral protein inhibitor
source organism Human immunodeficiency virus 1
molecule keywords Gag protein
total genus 47
structure length 146
sequence length 146
ec nomenclature
pdb deposition date 2013-01-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4inbA00
4WYMA 4B4NA 3H47A 1G03A 4U0CA 4PH2A 4DGEC 4XFYA 1M9YC 2GOLB 2M8PA 4E91A 1D1DA 4U0DA 2XGUA 2WLVA 2V4XA 2Y4ZA 2M8LA 3P05A 4QNBA 1EIAA 3MGEA 4U0FA 2PXRC 4U0BA 1AFVA 1U7KA 1GWPA 1AK4C 1E6JP 5HGLA 2JPRA 4LQWC 2X83A 4INBA 4PH3A 4XFZA 4XFXA 2X2DD 1M9EC 4NX4C 1P7NA 2EIAA 1M9CC 3BP9A 4E92A 4DGAC 5HGOA 2GONA 1M9XC 4U0EA 2X82A 2LF4A 2M8NA 4XRQA 1L6NA 2PWMA 2XGVA 1EM9A 5HGNA 2XDEA 1M9DC 5HGKA 4U0AA 2PWOA 4HTWA 5HGMA 2XGYA 2WLVB 4PH0A 3H4EA 3NTEA 1QRJA 2KGFA 4J93A 1M9FC 4XROA 5JPAA
chains in the Genus database with same CATH superfamily
4WYMA 4B4NA 3H47A 1G03A 4U0CA 4PH2A 4DGEC 4XFYA 1M9YC 2GOLB 2M8PA 4E91A 1D1DA 4U0DA 2XGUA 2WLVA 2V4XA 2Y4ZA 2M8LA 3P05A 4QNBA 1EIAA 3MGEA 4U0FA 2PXRC 4U0BA 1AFVA 1U7KA 1GWPA 1AK4C 1E6JP 5HGLA 2JPRA 4LQWC 2X83A 4INBA 4PH3A 4XFZA 4XFXA 2X2DD 1M9EC 4NX4C 1P7NA 2EIAA 1M9CC 3BP9A 4E92A 4DGAC 5HGOA 2GONA 1M9XC 4U0EA 2X82A 2LF4A 2M8NA 4XRQA 1L6NA 2PWMA 2XGVA 1EM9A 5HGNA 2XDEA 1M9DC 5HGKA 4U0AA 2PWOA 4HTWA 5HGMA 2XGYA 2WLVB 4PH0A 3H4EA 3NTEA 1QRJA 2KGFA 4J93A 1M9FC 4XROA 5JPAA
chains in the Genus database with same CATH topology
4WYMA 4B4NA 3H47A 1G03A 4U0CA 4PH2A 4DGEC 4XFYA 1M9YC 2GOLB 2M8PA 4E91A 1D1DA 4U0DA 2XGUA 2WLVA 2V4XA 2Y4ZA 2M8LA 3P05A 4QNBA 1EIAA 3MGEA 4U0FA 2PXRC 4U0BA 1AFVA 1U7KA 1GWPA 1AK4C 1E6JP 5HGLA 2JPRA 4LQWC 2X83A 4INBA 4PH3A 4XFZA 4XFXA 2X2DD 1M9EC 4NX4C 1P7NA 2EIAA 1M9CC 3BP9A 4E92A 4DGAC 5HGOA 2GONA 1M9XC 4U0EA 2X82A 2LF4A 2M8NA 4XRQA 1L6NA 2PWMA 2XGVA 1EM9A 5HGNA 2XDEA 1M9DC 5HGKA 4U0AA 2PWOA 4HTWA 5HGMA 2XGYA 2WLVB 4PH0A 3H4EA 3NTEA 1QRJA 2KGFA 4J93A 1M9FC 4XROA 5JPAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WYM A;  4B4N A;  3H47 A;  1G03 A;  4U0C A;  4PH2 A;  4DGE C;  4XFY A;  1M9Y C;  2GOL B;  2M8P A;  4E91 A;  1D1D A;  4U0D A;  2XGU A;  2WLV A;  2V4X A;  2Y4Z A;  2M8L A;  3P05 A;  4QNB A;  1EIA A;  3MGE A;  4U0F A;  2PXR C;  4U0B A;  1AFV A;  1U7K A;  1GWP A;  1AK4 C;  1E6J P;  5HGL A;  2JPR A;  4LQW C;  2X83 A;  4INB A;  4PH3 A;  4XFZ A;  4XFX A;  2X2D D;  1M9E C;  4NX4 C;  1P7N A;  2EIA A;  1M9C C;  3BP9 A;  4E92 A;  4DGA C;  5HGO A;  2GON A;  1M9X C;  4U0E A;  2X82 A;  2LF4 A;  2M8N A;  4XRQ A;  1L6N A;  2PWM A;  2XGV A;  1EM9 A;  5HGN A;  2XDE A;  1M9D C;  5HGK A;  4U0A A;  2PWO A;  4HTW A;  5HGM A;  2XGY A;  2WLV B;  4PH0 A;  3H4E A;  3NTE A;  1QRJ A;  2KGF A;  4J93 A;  1M9F C;  4XRO A;  5JPA A; 
#chains in the Genus database with same CATH topology
 4WYM A;  4B4N A;  3H47 A;  1G03 A;  4U0C A;  4PH2 A;  4DGE C;  4XFY A;  1M9Y C;  2GOL B;  2M8P A;  4E91 A;  1D1D A;  4U0D A;  2XGU A;  2WLV A;  2V4X A;  2Y4Z A;  2M8L A;  3P05 A;  4QNB A;  1EIA A;  3MGE A;  4U0F A;  2PXR C;  4U0B A;  1AFV A;  1U7K A;  1GWP A;  1AK4 C;  1E6J P;  5HGL A;  2JPR A;  4LQW C;  2X83 A;  4INB A;  4PH3 A;  4XFZ A;  4XFX A;  2X2D D;  1M9E C;  4NX4 C;  1P7N A;  2EIA A;  1M9C C;  3BP9 A;  4E92 A;  4DGA C;  5HGO A;  2GON A;  1M9X C;  4U0E A;  2X82 A;  2LF4 A;  2M8N A;  4XRQ A;  1L6N A;  2PWM A;  2XGV A;  1EM9 A;  5HGN A;  2XDE A;  1M9D C;  5HGK A;  4U0A A;  2PWO A;  4HTW A;  5HGM A;  2XGY A;  2WLV B;  4PH0 A;  3H4E A;  3NTE A;  1QRJ A;  2KGF A;  4J93 A;  1M9F C;  4XRO A;  5JPA A; 
#chains in the Genus database with same CATH homology
 4WYM A;  4B4N A;  3H47 A;  1G03 A;  4U0C A;  4PH2 A;  4DGE C;  4XFY A;  1M9Y C;  2GOL B;  2M8P A;  4E91 A;  1D1D A;  4U0D A;  2XGU A;  2WLV A;  2V4X A;  2Y4Z A;  2M8L A;  3P05 A;  4QNB A;  1EIA A;  3MGE A;  4U0F A;  2PXR C;  4U0B A;  1AFV A;  1U7K A;  1GWP A;  1AK4 C;  1E6J P;  5HGL A;  2JPR A;  4LQW C;  2X83 A;  4INB A;  4PH3 A;  4XFZ A;  4XFX A;  2X2D D;  1M9E C;  4NX4 C;  1P7N A;  2EIA A;  1M9C C;  3BP9 A;  4E92 A;  4DGA C;  5HGO A;  2GON A;  1M9X C;  4U0E A;  2X82 A;  2LF4 A;  2M8N A;  4XRQ A;  1L6N A;  2PWM A;  2XGV A;  1EM9 A;  5HGN A;  2XDE A;  1M9D C;  5HGK A;  4U0A A;  2PWO A;  4HTW A;  5HGM A;  2XGY A;  2WLV B;  4PH0 A;  3H4E A;  3NTE A;  1QRJ A;  2KGF A;  4J93 A;  1M9F C;  4XRO A;  5JPA A; 
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