4IOAJ

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
136
structure length
136
Chain Sequence
KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 20
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 4ioaJ01
3CCVH 3CPWH 5JVHJ 1YIJH 3CF5J 5JVGJ 3I55H 1YJWH 1K8AJ 3CC4H 1N8RJ 3PIPJ 3CCQH 3CCMH 4WFNJ 1QVGH 1Q82J 1VQ6H 1QVFH 1YJNH 1KQSH 3CCJH 2ZJRJ 1JJ2H 1VQPH 3I56H 1VQOH 1KD1J 2ZJPJ 3CCSH 1KC8J 3CCRH 3CMEH 3J7ZM 1YJ9H 3DLLJ 5GAGN 4IO9J 1NJIJ 3CC2H 4IOAJ 2QEXH 3OW2H 1YI2H 5AN9F 4WCEJ 3G71H 3CD6H 4WFAJ 5H1SO 1VQLH 3CMAH 4WFBJ 3G6EH 3PIOJ 1Y69K 1WKIA 3CCUH 4UY8M 5MLCO 1VQNH 5GAEN 4IOCJ 5DM7J 1M1KJ 5GADN 1M90J 1VQ8H 5GAHN 1VQMH 1S72H 1VQ9H 2OTJH 4WF9J 1K9MJ 1VQ5H 2QA4H 1YITH 3CCEH 3G4SH 1Q86J 1Q81J 2ZJQJ 1VQKH 5DM6J 3CCLH 3CXCH 1W2BH 3CC7H 1VQ4H 1YHQH 2OTLH 2PA2A 5HL7J 1Q7YJ 1VQ7H 4U67J 1K73J
chains in the Genus database with same CATH superfamily
3CCVH 3CPWH 3WO0A 1AZYA 5JVHJ 1UOUA 1YIJH 4USAA 3RPFA 3NVWC 3I55H 3CF5J 5JVGJ 2J0FA 1YJWH 1K8AJ 3B9JC 3H5QA 4YEKA 3CC4H 1N8RJ 3WO1A 3PIPJ 4US9A 3CCQH 3CCMH 3FC4A 4I9AA 4WFNJ 1QVGH 3PAJA 1Q82J 1VQ6H 3C2EA 1QVFH 3AMZA 1YJNH 5AYXA 1FFUB 1KQSH 1V97A 3CCJH 1N5WB 2ZJRJ 2JBMA 5HULA 1JJ2H 2WP4A 1VQPH 4LHMA 2DSJA 3I56H 1VQOH 2W3SB 4GA4A 1KD1J 3GNNA 1QAPA 4US8A 2E3TA 2ZJPJ 2W55B 3CCSH 1K73J 1DGJA 1N5XA 2B7QA 1KC8J 3CCRH 1QPOA 1QPQA 3CMEH 3J7ZM 1JROB 2Q5WE 1YJ9H 1O4UA 1VDVA 3DLLJ 1QPNA 4ZOHA 5GAGN 4IO9J 1N63B 4XR5A 5HUOA 1NJIJ 5MPOC 5AYZA 5HUPA 3CC2H 1YTKA 4IOAJ 2QIEA 2QEXH 3OW2H 1YI2H 3AM9A 2W54B 5AN9F 3L4PA 4WCEJ 4C7YA 3G71H 3CD6H 4WFAJ 5H1SO 1VQLH 1NVIE 3C2VA 3TQVA 1N60B 4WFBJ 3CMAH 5EY3A 1VLBA 3C2OA 1RM6A 3NS1C 4KWVA 3G6EH 2WK6A 4C80A 5AYYA 2WK5A 1NVJA 3PIOJ 1FIQC 1Y69K 1WKIA 2TPTA 3NVZC 1N62B 1FM0E 3CCUH 4UY8M 1YTDA 5MLCO 1VQNH 5GAEN 1FO4A 3NVVC 4IOCJ 3AN1A 4C7ZA 5DM7J 1M1KJ 5GADN 1M90J 1VQ8H 5GAHN 3NVYC 1VQMH 1BRWA 1QPRA 1S72H 2B7NA 1VQ9H 2OTJH 4X46A 3FAHA 4WF9J 1K9MJ 1VQ5H 1YTEA 2QA4H 1FFVB 3BIIE 3WNZA 1YITH 4GA6A 3CCEH 3G4SH 1X1OA 1Q86J 1Q81J 2ZJQJ 4KWWA 2I1OA 1VQKH 4GA5A 5DM6J 3L0GA 1OTPA 3SR6C 3CCLH 3EUB4 4EAFA 2W3RB 3CXCH 1SB3A 1W2BH 3CC7H 1VQ4H 1WYGA 4YYYA 2B7PA 2OMDA 3ETRC 1ZXIB 2PA2A 4AP8A 4EADA 5HL7J 1YHQH 2OTLH 2I14A 1SIJA 1FMAE 3C2FA 1JRPB 3C2RA 1Q7YJ 5EP8A 3NRZC 1VQ7H 4U67J 3VMMA 1N61B
chains in the Genus database with same CATH topology
3CCVH 3CPWH 5JVHJ 1YIJH 3CF5J 5JVGJ 3I55H 1YJWH 1K8AJ 3CC4H 1N8RJ 3PIPJ 3CCQH 3CCMH 4WFNJ 1QVGH 1Q82J 1VQ6H 1QVFH 1YJNH 1KQSH 3CCJH 2ZJRJ 1JJ2H 1VQPH 3I56H 1VQOH 1KD1J 2ZJPJ 3CCSH 1KC8J 3CCRH 3CMEH 3J7ZM 1YJ9H 3DLLJ 5GAGN 4IO9J 1NJIJ 3CC2H 4IOAJ 2QEXH 3OW2H 1YI2H 5AN9F 4WCEJ 3G71H 3CD6H 4WFAJ 5H1SO 1VQLH 3CMAH 4WFBJ 3G6EH 3PIOJ 1Y69K 1WKIA 3CCUH 4UY8M 5MLCO 1VQNH 5GAEN 4IOCJ 5DM7J 1M1KJ 5GADN 1M90J 1VQ8H 5GAHN 1VQMH 1S72H 1VQ9H 2OTJH 4WF9J 1K9MJ 1VQ5H 2QA4H 1YITH 3CCEH 3G4SH 1Q86J 1Q81J 2ZJQJ 1VQKH 5DM6J 3CCLH 3CXCH 1W2BH 3CC7H 1VQ4H 1YHQH 2OTLH 2PA2A 5HL7J 1Q7YJ 1VQ7H 4U67J 1K73J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCV H;  3CPW H;  5JVH J;  1YIJ H;  3CF5 J;  5JVG J;  3I55 H;  1YJW H;  1K8A J;  3CC4 H;  1N8R J;  3PIP J;  3CCQ H;  3CCM H;  4WFN J;  1QVG H;  1Q82 J;  1VQ6 H;  1QVF H;  1YJN H;  1KQS H;  3CCJ H;  2ZJR J;  1JJ2 H;  1VQP H;  3I56 H;  1VQO H;  1KD1 J;  2ZJP J;  3CCS H;  1KC8 J;  3CCR H;  3CME H;  3J7Z M;  1YJ9 H;  3DLL J;  5GAG N;  4IO9 J;  1NJI J;  3CC2 H;  4IOA J;  2QEX H;  3OW2 H;  1YI2 H;  5AN9 F;  4WCE J;  3G71 H;  3CD6 H;  4WFA J;  5H1S O;  1VQL H;  3CMA H;  4WFB J;  3G6E H;  3PIO J;  1Y69 K;  1WKI A;  3CCU H;  4UY8 M;  5MLC O;  1VQN H;  5GAE N;  4IOC J;  5DM7 J;  1M1K J;  5GAD N;  1M90 J;  1VQ8 H;  5GAH N;  1VQM H;  1S72 H;  1VQ9 H;  2OTJ H;  4WF9 J;  1K9M J;  1VQ5 H;  2QA4 H;  1YIT H;  3CCE H;  3G4S H;  1Q86 J;  1Q81 J;  2ZJQ J;  1VQK H;  5DM6 J;  3CCL H;  3CXC H;  1W2B H;  3CC7 H;  1VQ4 H;  1YHQ H;  2OTL H;  2PA2 A;  5HL7 J;  1Q7Y J;  1VQ7 H;  4U67 J;  1K73 J; 
#chains in the Genus database with same CATH topology
 3CCV H;  3CPW H;  3WO0 A;  1AZY A;  5JVH J;  1UOU A;  1YIJ H;  4USA A;  3RPF A;  3NVW C;  3I55 H;  3CF5 J;  5JVG J;  2J0F A;  1YJW H;  1K8A J;  3B9J C;  3H5Q A;  4YEK A;  3CC4 H;  1N8R J;  3WO1 A;  3PIP J;  4US9 A;  3CCQ H;  3CCM H;  3FC4 A;  4I9A A;  4WFN J;  1QVG H;  3PAJ A;  1Q82 J;  1VQ6 H;  3C2E A;  1QVF H;  3AMZ A;  1YJN H;  5AYX A;  1FFU B;  1KQS H;  1V97 A;  3CCJ H;  1N5W B;  2ZJR J;  2JBM A;  5HUL A;  1JJ2 H;  2WP4 A;  1VQP H;  4LHM A;  2DSJ A;  3I56 H;  1VQO H;  2W3S B;  4GA4 A;  1KD1 J;  3GNN A;  1QAP A;  4US8 A;  2E3T A;  2ZJP J;  2W55 B;  3CCS H;  1K73 J;  1DGJ A;  1N5X A;  2B7Q A;  1KC8 J;  3CCR H;  1QPO A;  1QPQ A;  3CME H;  3J7Z M;  1JRO B;  2Q5W E;  1YJ9 H;  1O4U A;  1VDV A;  3DLL J;  1QPN A;  4ZOH A;  5GAG N;  4IO9 J;  1N63 B;  4XR5 A;  5HUO A;  1NJI J;  5MPO C;  5AYZ A;  5HUP A;  3CC2 H;  1YTK A;  4IOA J;  2QIE A;  2QEX H;  3OW2 H;  1YI2 H;  3AM9 A;  2W54 B;  5AN9 F;  3L4P A;  4WCE J;  4C7Y A;  3G71 H;  3CD6 H;  4WFA J;  5H1S O;  1VQL H;  1NVI E;  3C2V A;  3TQV A;  1N60 B;  4WFB J;  3CMA H;  5EY3 A;  1VLB A;  3C2O A;  1RM6 A;  3NS1 C;  4KWV A;  3G6E H;  2WK6 A;  4C80 A;  5AYY A;  2WK5 A;  1NVJ A;  3PIO J;  1FIQ C;  1Y69 K;  1WKI A;  2TPT A;  3NVZ C;  1N62 B;  1FM0 E;  3CCU H;  4UY8 M;  1YTD A;  5MLC O;  1VQN H;  5GAE N;  1FO4 A;  3NVV C;  4IOC J;  3AN1 A;  4C7Z A;  5DM7 J;  1M1K J;  5GAD N;  1M90 J;  1VQ8 H;  5GAH N;  3NVY C;  1VQM H;  1BRW A;  1QPR A;  1S72 H;  2B7N A;  1VQ9 H;  2OTJ H;  4X46 A;  3FAH A;  4WF9 J;  1K9M J;  1VQ5 H;  1YTE A;  2QA4 H;  1FFV B;  3BII E;  3WNZ A;  1YIT H;  4GA6 A;  3CCE H;  3G4S H;  1X1O A;  1Q86 J;  1Q81 J;  2ZJQ J;  4KWW A;  2I1O A;  1VQK H;  4GA5 A;  5DM6 J;  3L0G A;  1OTP A;  3SR6 C;  3CCL H;  3EUB 4;  4EAF A;  2W3R B;  3CXC H;  1SB3 A;  1W2B H;  3CC7 H;  1VQ4 H;  1WYG A;  4YYY A;  2B7P A;  2OMD A;  3ETR C;  1ZXI B;  2PA2 A;  4AP8 A;  4EAD A;  5HL7 J;  1YHQ H;  2OTL H;  2I14 A;  1SIJ A;  1FMA E;  3C2F A;  1JRP B;  3C2R A;  1Q7Y J;  5EP8 A;  3NRZ C;  1VQ7 H;  4U67 J;  3VMM A;  1N61 B; 
#chains in the Genus database with same CATH homology
 3CCV H;  3CPW H;  5JVH J;  1YIJ H;  3CF5 J;  5JVG J;  3I55 H;  1YJW H;  1K8A J;  3CC4 H;  1N8R J;  3PIP J;  3CCQ H;  3CCM H;  4WFN J;  1QVG H;  1Q82 J;  1VQ6 H;  1QVF H;  1YJN H;  1KQS H;  3CCJ H;  2ZJR J;  1JJ2 H;  1VQP H;  3I56 H;  1VQO H;  1KD1 J;  2ZJP J;  3CCS H;  1KC8 J;  3CCR H;  3CME H;  3J7Z M;  1YJ9 H;  3DLL J;  5GAG N;  4IO9 J;  1NJI J;  3CC2 H;  4IOA J;  2QEX H;  3OW2 H;  1YI2 H;  5AN9 F;  4WCE J;  3G71 H;  3CD6 H;  4WFA J;  5H1S O;  1VQL H;  3CMA H;  4WFB J;  3G6E H;  3PIO J;  1Y69 K;  1WKI A;  3CCU H;  4UY8 M;  5MLC O;  1VQN H;  5GAE N;  4IOC J;  5DM7 J;  1M1K J;  5GAD N;  1M90 J;  1VQ8 H;  5GAH N;  1VQM H;  1S72 H;  1VQ9 H;  2OTJ H;  4WF9 J;  1K9M J;  1VQ5 H;  2QA4 H;  1YIT H;  3CCE H;  3G4S H;  1Q86 J;  1Q81 J;  2ZJQ J;  1VQK H;  5DM6 J;  3CCL H;  3CXC H;  1W2B H;  3CC7 H;  1VQ4 H;  1YHQ H;  2OTL H;  2PA2 A;  5HL7 J;  1Q7Y J;  1VQ7 H;  4U67 J;  1K73 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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