4ISAA

Crystal structure of the escherichia coli lpxc/bb-78485 complex
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
300
structure length
300
Chain Sequence
b'MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
publication title Structural Basis of the Promiscuous Inhibitor Susceptibility of Escherichia coli LpxC.
pubmed doi rcsb
total genus 90
structure length 300
sequence length 300
ec nomenclature ec 3.5.1.-:
pdb deposition date 2013-01-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4isaA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4isaA02
2IESA 3P76A 4FW5A 1P42A 4MDTA 3PS3A 5DRPA 1YHCA 4LCHA 4U3BA 4FW7A 4FW3A 4LCFA 4MQYA 4FW4A 5DRQA 2IERA 2J65A 4LCGA 2JT2A 5DROA 3U1YA 4OKGA 4J3DA 3PS2A 5DRRA 2GO3A 1YH8A 4U3DA 2VESA 3P3CA 3UHMA 1XXEA 2GO4A 3P3GA 4FW6A 3NZKA 3P3EA 3PS1A 4ISAA 4IS9A 2O3ZA 4OZEA
chains in the Genus database with same CATH superfamily
5K36E 4DR6E 1MG7A 2UXBE 4B3RI 4LF9E 2ZBKB 1Z0WA 2J65A 4JI1E 3LPSA 3DD6A 1N0VC 2PO1A 2JE6B 2JEAA 3WU6A 4JI4E 4QNKA 4LFBI 3B82A 3J81Q 3J80Q 4OX9E 2BM0A 4R1FA 4JI3E 4DR4I 2F4VI 1ZM3A 2CGEA 4DR1E 1XXEA 1XMOE 2HHHE 3QT6A 2E5LI 1ZM4A 2UUBI 5DNLA 1FWLA 4JI4I 1P42A 4PRXA 4DR5E 1A6FA 4OO1B 2GQ0A 2HFUA 3JAMC 4LFAE 4GKJE 3ZZTA 4OO1D 4DV0E 5C0XC 2NPFA 4B3ME 1USUA 4NXNI 1N33I 3PYGA 1Z5BA 4LOMA 4YY3I 4KHPE 4IZKA 3UHMA 3OTOE 5K36A 3PYFA 1N34I 4FW6A 4JV5I 1XMQE 4DR3E 3V2UC 2HK3A 2IESA 2HKEA 2JEBA 3PS3A 1H73A 4FW3A 4DPYA 4YHHI 4IZJB 2IERA 5GMEA 2X7IA 4LCGA 4B3TI 4LFCE 2CG9A 3J7AG 4OO1A 1Z0CA 4UT4A 4J3DA 2OI2A 1ELOA 4IFDA 3QT5A 4DUYI 2PO1B 3Q6NA 3P3CA 4MYTA 5LMNE 4DV7E 2BA1G 2NN6C 2V2QA 4AIDA 5C0XD 4WUCA 4JG4A 5DRPA 1IBKE 4DV1I 4LCFA 5FLXC 5IWAI 2UXDI 1ZM2A 2Z5BA 2ZM6E 2JEBB 4FW9A 1IBME 4MU3A 4N3OA 4DV3E 1H7SA 2BR2A 1EA6A 5JEAC 4DU8A 3GLLA 1HNZI 2O1TA 3HJCA 2Z5CA 4LF6E 4FN5A 4JI7E 2DEIA 4IS9A 4WUDA 4FW5A 5A2QC 4K0KI 2C37A 1FJGI 2C39A 4UTGA 4JI2E 4X65E 2WW4A 3QT7A 5C0XE 4DV2I 2VQEI 2X36A 5LL6R 1I94I 2PO2A 3PS2A 2C38B 2GO3A 4BA1A 4WUBA 4DV4I 1KKHA 1FJGE 1YH8A 1USVA 2GO4A 2IOQA 4JI1I 3B4TA 4B3MI 2ZITA 1N32E 3KRNA 4NXNE 1N33E 2PO2B 3Q1QA 3V5RA 2PNMA 1B63A 1BKNA 2UUCE 1XNRI 1HNXE 1OYRA 5L3JA 4FW4A 4LPFA 5EL9A 2HHHI 1Z0VA 2PO0B 4JI5E 1N32I 2UUBE 2BV3A 3HULA 3D4JA 4DV6I 1Z5AA 4JI0I 5BR8E 4JI5I 2WP8A 1RR9A 5K36D 3ZM7A 4FWDA 2PO0A 2AJ4A 4FW7A 1NHHA 4LF7I 3J7AM 4JI6E 4X62I 2Z5CB 3U1KA 1KIJA 5DROA 3T1HI 1U2RA 5C0XF 1Y5YA 2UUAE 2WNRB 5C0XB 4X64I 1IBKI 4YHHE 1Z0GA 2UXDE 4DR2I 2Z5BB 1IBMI 2JE6A 5ELWA 3T1HE 4DR7I 1Z0EA 2UUAI 1UDSA 4X64E 3ZZ0A 4DUYE 2IOPA 1MX0A 4DV7I 3H1CA 1Y60A 2VQFI 4JI8I 4XTJA 4K0KE 4B3RE 4DR7E 1S4EA 2PNLA 4DPXA 3P06A 4NXMI 3LTOA 4U3DA 1R6LA 3ZKBA 4I3HA 5IWAE 1HNWE 1UDNA 2C39B 2ZM6I 3J80C 4IZJD 2VQEE 1B62A 3M85D 2O3ZA 3P76A 1N0UA 2NN6F 4MU0A 3GONA 4DUZE 4DV4E 4DPTA 4P52A 4JI3I 2F4VE 4DR4E 5DRQA 1PKPA 4OO1F 4LF4I 4MYUA 1H7UA 4BA2A 2UU9E 1VISA 3WU5A 2UXBI 4LF9I 4DR5I 4RPFA 4HYMA 2UXCE 4DV0I 1Y6ZA 2NN6E 4Z7YA 1J5EI 2UU9I 2HFSA 3K1JA 2R42A 1YHCA 1UDQA 4DPUA 4LF5I 3F0NA 4DV6E 4DR1I 5BR8I 4BA1B 1XMOI 1OJ4A 2E5LE 4AQYI 1Z0TA 1XMQI 1ZXMA 5JEAE 4GQUA 3QT8A 1XNRE 1KVKA 4DV5E 1HNXI 4LF5E 1XNQI 5A2QQ 4AM3A 4JI6I 4X62E 4DU7A 4B3TE 3CDIA 4LF8E 1NZ0A 4DV5I 2BR2B 4KQVA 2BA0D 1XNQE 2BM1A 1XHKA 2DEJA 4NBQA 4DR2E 3WU4A 1Z59A 3ZKDA 4JV5E 3PYDA 5FLXQ 3K17A 1N36E 5K36F 1WUUA 4HY1A 2NN6A 2VESA 4URLA 1IBLI 1S16A 4B3SE 3J81C 1Y4UA 3P3GA 2V2ZA 5LMUE 5DRRA 4DPWA 1Y4SA 4JI8E 2EFGA 4MU4A 3ZZUA 4IFDE 1NHJA 4NXME 2O1WA 2C38A 5IT9Q 1OYSA 1HNZE 4OO1E 2Z5EA 5JEAF 4IFDF 4USMA 4LF6I 5LMUI 3JAMQ 4OKGA 4ED4A 4DUZI 4FWGA 2GS8A 1HR0I 4JYAE 1HK7A 4IZJA 4DV1E 4JI2I 4X65I 3CDJA 4DV2E 4MU1A 4DXLA 4USKA 1PIEA 1FI4A 1ZXNA 3P3EA 2F1DA 1UEKA 1NHIA 1E3HA 1R6MA 4MDTA 1HR0E 4OX9I 4LCHA 4JYAI 4IZKB 2UXCI 2E1RA 1HNWI 5JEAB 2A2CA 2WP8B 4JI7I 4IFDD 2V2VA 2JT2A 4PRVA 3M85G 4DR6I 2V8PA 3U1YA 2PNZB 3WU3A 2NN6D 2CZ9A 4PU9A 1EI1A 3H4LA 4QNJA 4LF4E 4AIMA 3CWVA 4OZEA 5EKWA 3L7ZA 4LFBE 2NN6B 1I94E 4BA2B 2VF3A 1KTVA 3M6AA 5GMDA 2O1VA 1FNMA 3OTOI 1DARA 1N34E 2HKJA 2V34A 4Z7CA 1MU5A 5JEAD 1J5EE 4LF8I 2HK2A 2LJPA 2UUCI 1Z0BA 2C37B 4LFAI 4GKJI 3HKMA 4FWHA 4LF7E 1QZRA 1K47A 1ZM9A 1RHYA 4P7AA 4AQYE 5IT9C 3B78A 5JEAA 4OO1C 2BA0G 1H74A 4IFDC 1N36I 1RREA 4YY3E 4HACB 4MQYA 3PYEA 4KHPI 2WNRA 2A2DA 4JI0E 5LMNI 4DR3I 2CVEA 5FWKA 3M7NG 4GKKI 1PVGA 3GMEA 4X66I 4HACA 3GCMA 3L7ZB 2AE8A 3NZKA 4LFCI 3PS1A 1E3PA 2R3VA 2VQFE 1VI7A 4GKKE 4HXZA 2JEAB 3M7ND 4DV3I 4X66E 2PNZA 4ZVIA 4EMDA 4U3BA 5C0XA 1FKAE 1Z5CA 3T1YI 4IFDB 2Q2EB 1IBLE 3K85A 4B3SI 2BA1D 3Q6MA 3LNUA 3PRYA 5K36B 1H72C 2XEXA 5DNXA 3B8HA 1D6TA 2O1UA 5K36C 3T1YE 2J7KA 1FWKA 1UDOA 1OYPA 4ISAA 4M1KA
chains in the Genus database with same CATH topology
2IESA 3P76A 4FW5A 1P42A 4MDTA 3PS3A 5DRPA 1YHCA 4LCHA 4U3BA 4FW7A 4FW3A 4LCFA 4MQYA 4FW4A 5DRQA 2IERA 2J65A 4LCGA 2JT2A 5DROA 3U1YA 4OKGA 4J3DA 3PS2A 5DRRA 2GO3A 1YH8A 4U3DA 2VESA 3P3CA 3UHMA 1XXEA 2GO4A 3P3GA 4FW6A 3NZKA 3P3EA 3PS1A 4ISAA 4IS9A 2O3ZA 4OZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IES A;  3P76 A;  4FW5 A;  1P42 A;  4MDT A;  3PS3 A;  5DRP A;  1YHC A;  4LCH A;  4U3B A;  4FW7 A;  4FW3 A;  4LCF A;  4MQY A;  4FW4 A;  5DRQ A;  2IER A;  2J65 A;  4LCG A;  2JT2 A;  5DRO A;  3U1Y A;  4OKG A;  4J3D A;  3PS2 A;  5DRR A;  2GO3 A;  1YH8 A;  4U3D A;  2VES A;  3P3C A;  3UHM A;  1XXE A;  2GO4 A;  3P3G A;  4FW6 A;  3NZK A;  3P3E A;  3PS1 A;  4ISA A;  4IS9 A;  2O3Z A;  4OZE A; 
#chains in the Genus database with same CATH topology
 5K36 E;  4DR6 E;  1MG7 A;  2UXB E;  4B3R I;  4LF9 E;  2ZBK B;  1Z0W A;  2J65 A;  4JI1 E;  3LPS A;  3DD6 A;  1N0V C;  2PO1 A;  2JE6 B;  2JEA A;  3WU6 A;  4JI4 E;  4QNK A;  4LFB I;  3B82 A;  3J81 Q;  3J80 Q;  4OX9 E;  2BM0 A;  4R1F A;  4JI3 E;  4DR4 I;  2F4V I;  1ZM3 A;  2CGE A;  4DR1 E;  1XXE A;  1XMO E;  2HHH E;  3QT6 A;  2E5L I;  1ZM4 A;  2UUB I;  5DNL A;  1FWL A;  4JI4 I;  1P42 A;  4PRX A;  4DR5 E;  1A6F A;  4OO1 B;  2GQ0 A;  2HFU A;  3JAM C;  4LFA E;  4GKJ E;  3ZZT A;  4OO1 D;  4DV0 E;  5C0X C;  2NPF A;  4B3M E;  1USU A;  4NXN I;  1N33 I;  3PYG A;  1Z5B A;  4LOM A;  4YY3 I;  4KHP E;  4IZK A;  3UHM A;  3OTO E;  5K36 A;  3PYF A;  1N34 I;  4FW6 A;  4JV5 I;  1XMQ E;  4DR3 E;  3V2U C;  2HK3 A;  2IES A;  2HKE A;  2JEB A;  3PS3 A;  1H73 A;  4FW3 A;  4DPY A;  4YHH I;  4IZJ B;  2IER A;  5GME A;  2X7I A;  4LCG A;  4B3T I;  4LFC E;  2CG9 A;  3J7A G;  4OO1 A;  1Z0C A;  4UT4 A;  4J3D A;  2OI2 A;  1ELO A;  4IFD A;  3QT5 A;  4DUY I;  2PO1 B;  3Q6N A;  3P3C A;  4MYT A;  5LMN E;  4DV7 E;  2BA1 G;  2NN6 C;  2V2Q A;  4AID A;  5C0X D;  4WUC A;  4JG4 A;  5DRP A;  1IBK E;  4DV1 I;  4LCF A;  5FLX C;  5IWA I;  2UXD I;  1ZM2 A;  2Z5B A;  2ZM6 E;  2JEB B;  4FW9 A;  1IBM E;  4MU3 A;  4N3O A;  4DV3 E;  1H7S A;  2BR2 A;  1EA6 A;  5JEA C;  4DU8 A;  3GLL A;  1HNZ I;  2O1T A;  3HJC A;  2Z5C A;  4LF6 E;  4FN5 A;  4JI7 E;  2DEI A;  4IS9 A;  4WUD A;  4FW5 A;  5A2Q C;  4K0K I;  2C37 A;  1FJG I;  2C39 A;  4UTG A;  4JI2 E;  4X65 E;  2WW4 A;  3QT7 A;  5C0X E;  4DV2 I;  2VQE I;  2X36 A;  5LL6 R;  1I94 I;  2PO2 A;  3PS2 A;  2C38 B;  2GO3 A;  4BA1 A;  4WUB A;  4DV4 I;  1KKH A;  1FJG E;  1YH8 A;  1USV A;  2GO4 A;  2IOQ A;  4JI1 I;  3B4T A;  4B3M I;  2ZIT A;  1N32 E;  3KRN A;  4NXN E;  1N33 E;  2PO2 B;  3Q1Q A;  3V5R A;  2PNM A;  1B63 A;  1BKN A;  2UUC E;  1XNR I;  1HNX E;  1OYR A;  5L3J A;  4FW4 A;  4LPF A;  5EL9 A;  2HHH I;  1Z0V A;  2PO0 B;  4JI5 E;  1N32 I;  2UUB E;  2BV3 A;  3HUL A;  3D4J A;  4DV6 I;  1Z5A A;  4JI0 I;  5BR8 E;  4JI5 I;  2WP8 A;  1RR9 A;  5K36 D;  3ZM7 A;  4FWD A;  2PO0 A;  2AJ4 A;  4FW7 A;  1NHH A;  4LF7 I;  3J7A M;  4JI6 E;  4X62 I;  2Z5C B;  3U1K A;  1KIJ A;  5DRO A;  3T1H I;  1U2R A;  5C0X F;  1Y5Y A;  2UUA E;  2WNR B;  5C0X B;  4X64 I;  1IBK I;  4YHH E;  1Z0G A;  2UXD E;  4DR2 I;  2Z5B B;  1IBM I;  2JE6 A;  5ELW A;  3T1H E;  4DR7 I;  1Z0E A;  2UUA I;  1UDS A;  4X64 E;  3ZZ0 A;  4DUY E;  2IOP A;  1MX0 A;  4DV7 I;  3H1C A;  1Y60 A;  2VQF I;  4JI8 I;  4XTJ A;  4K0K E;  4B3R E;  4DR7 E;  1S4E A;  2PNL A;  4DPX A;  3P06 A;  4NXM I;  3LTO A;  4U3D A;  1R6L A;  3ZKB A;  4I3H A;  5IWA E;  1HNW E;  1UDN A;  2C39 B;  2ZM6 I;  3J80 C;  4IZJ D;  2VQE E;  1B62 A;  3M85 D;  2O3Z A;  3P76 A;  1N0U A;  2NN6 F;  4MU0 A;  3GON A;  4DUZ E;  4DV4 E;  4DPT A;  4P52 A;  4JI3 I;  2F4V E;  4DR4 E;  5DRQ A;  1PKP A;  4OO1 F;  4LF4 I;  4MYU A;  1H7U A;  4BA2 A;  2UU9 E;  1VIS A;  3WU5 A;  2UXB I;  4LF9 I;  4DR5 I;  4RPF A;  4HYM A;  2UXC E;  4DV0 I;  1Y6Z A;  2NN6 E;  4Z7Y A;  1J5E I;  2UU9 I;  2HFS A;  3K1J A;  2R42 A;  1YHC A;  1UDQ A;  4DPU A;  4LF5 I;  3F0N A;  4DV6 E;  4DR1 I;  5BR8 I;  4BA1 B;  1XMO I;  1OJ4 A;  2E5L E;  4AQY I;  1Z0T A;  1XMQ I;  1ZXM A;  5JEA E;  4GQU A;  3QT8 A;  1XNR E;  1KVK A;  4DV5 E;  1HNX I;  4LF5 E;  1XNQ I;  5A2Q Q;  4AM3 A;  4JI6 I;  4X62 E;  4DU7 A;  4B3T E;  3CDI A;  4LF8 E;  1NZ0 A;  4DV5 I;  2BR2 B;  4KQV A;  2BA0 D;  1XNQ E;  2BM1 A;  1XHK A;  2DEJ A;  4NBQ A;  4DR2 E;  3WU4 A;  1Z59 A;  3ZKD A;  4JV5 E;  3PYD A;  5FLX Q;  3K17 A;  1N36 E;  5K36 F;  1WUU A;  4HY1 A;  2NN6 A;  2VES A;  4URL A;  1IBL I;  1S16 A;  4B3S E;  3J81 C;  1Y4U A;  3P3G A;  2V2Z A;  5LMU E;  5DRR A;  4DPW A;  1Y4S A;  4JI8 E;  2EFG A;  4MU4 A;  3ZZU A;  4IFD E;  1NHJ A;  4NXM E;  2O1W A;  2C38 A;  5IT9 Q;  1OYS A;  1HNZ E;  4OO1 E;  2Z5E A;  5JEA F;  4IFD F;  4USM A;  4LF6 I;  5LMU I;  3JAM Q;  4OKG A;  4ED4 A;  4DUZ I;  4FWG A;  2GS8 A;  1HR0 I;  4JYA E;  1HK7 A;  4IZJ A;  4DV1 E;  4JI2 I;  4X65 I;  3CDJ A;  4DV2 E;  4MU1 A;  4DXL A;  4USK A;  1PIE A;  1FI4 A;  1ZXN A;  3P3E A;  2F1D A;  1UEK A;  1NHI A;  1E3H A;  1R6M A;  4MDT A;  1HR0 E;  4OX9 I;  4LCH A;  4JYA I;  4IZK B;  2UXC I;  2E1R A;  1HNW I;  5JEA B;  2A2C A;  2WP8 B;  4JI7 I;  4IFD D;  2V2V A;  2JT2 A;  4PRV A;  3M85 G;  4DR6 I;  2V8P A;  3U1Y A;  2PNZ B;  3WU3 A;  2NN6 D;  2CZ9 A;  4PU9 A;  1EI1 A;  3H4L A;  4QNJ A;  4LF4 E;  4AIM A;  3CWV A;  4OZE A;  5EKW A;  3L7Z A;  4LFB E;  2NN6 B;  1I94 E;  4BA2 B;  2VF3 A;  1KTV A;  3M6A A;  5GMD A;  2O1V A;  1FNM A;  3OTO I;  1DAR A;  1N34 E;  2HKJ A;  2V34 A;  4Z7C A;  1MU5 A;  5JEA D;  1J5E E;  4LF8 I;  2HK2 A;  2LJP A;  2UUC I;  1Z0B A;  2C37 B;  4LFA I;  4GKJ I;  3HKM A;  4FWH A;  4LF7 E;  1QZR A;  1K47 A;  1ZM9 A;  1RHY A;  4P7A A;  4AQY E;  5IT9 C;  3B78 A;  5JEA A;  4OO1 C;  2BA0 G;  1H74 A;  4IFD C;  1N36 I;  1RRE A;  4YY3 E;  4HAC B;  4MQY A;  3PYE A;  4KHP I;  2WNR A;  2A2D A;  4JI0 E;  5LMN I;  4DR3 I;  2CVE A;  5FWK A;  3M7N G;  4GKK I;  1PVG A;  3GME A;  4X66 I;  4HAC A;  3GCM A;  3L7Z B;  2AE8 A;  3NZK A;  4LFC I;  3PS1 A;  1E3P A;  2R3V A;  2VQF E;  1VI7 A;  4GKK E;  4HXZ A;  2JEA B;  3M7N D;  4DV3 I;  4X66 E;  2PNZ A;  4ZVI A;  4EMD A;  4U3B A;  5C0X A;  1FKA E;  1Z5C A;  3T1Y I;  4IFD B;  2Q2E B;  1IBL E;  3K85 A;  4B3S I;  2BA1 D;  3Q6M A;  3LNU A;  3PRY A;  5K36 B;  1H72 C;  2XEX A;  5DNX A;  3B8H A;  1D6T A;  2O1U A;  5K36 C;  3T1Y E;  2J7K A;  1FWK A;  1UDO A;  1OYP A;  4ISA A;  4M1K A; 
#chains in the Genus database with same CATH homology
 2IES A;  3P76 A;  4FW5 A;  1P42 A;  4MDT A;  3PS3 A;  5DRP A;  1YHC A;  4LCH A;  4U3B A;  4FW7 A;  4FW3 A;  4LCF A;  4MQY A;  4FW4 A;  5DRQ A;  2IER A;  2J65 A;  4LCG A;  2JT2 A;  5DRO A;  3U1Y A;  4OKG A;  4J3D A;  3PS2 A;  5DRR A;  2GO3 A;  1YH8 A;  4U3D A;  2VES A;  3P3C A;  3UHM A;  1XXE A;  2GO4 A;  3P3G A;  4FW6 A;  3NZK A;  3P3E A;  3PS1 A;  4ISA A;  4IS9 A;  2O3Z A;  4OZE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...