4IU8A

Crystal structure of a membrane transporter (selenomethionine derivative)
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
443
structure length
422
Chain Sequence
LLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIALWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGQAHKEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of a nitrate transporter.
pubmed doi rcsb
molecule keywords Nitrite extrusion protein 2
molecule tags Transport protein
source organism Escherichia coli
total genus 121
structure length 422
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4iu8A01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4iu8A02
1PW4A 2CFQA 4APSA 4ZYRA 2XUTA 2Y5YA 4OH3A 5EQIA 4W6VA 4IKVA 4D2DA 5C65A 4PYPA 1PV6A 4OAAA 5D59A 4IKWA 4LDSA 5EQGA 4JR9A 4U4WA 4QIQA 4Q65A 2CFPA 5A2NA 5A2OA 4IKYA 4D2BA 3O7QA 5D6KA 4XNJA 4TPJA 4LEPA 5D58A 2V8NA 4IKZA 4ZW9A 4D2CA 4U4VA 4GBZA 4J05A 4IU9A 4TPGA 5EQHA 4UVMA 1PV7A 4ZWBA 3O7PA 4ZWCA 4YB9D 4TPHA 4YBQA 5GXBA 4IKXA 3WDOA 4GBYA 4IU8A 4JREA 4JA3A 4XNIA 4U4TA 4GC0A
chains in the Genus database with same CATH superfamily
1N1FA 2XUTA 1HZIA 1JLIA 5KNHI 4U4WA 4DOHA 4QIQA 3DI2A 1D9CA 2R93D 2B8ZA 1PW6A 1BGDA 1HWHA 1RHGA 3DLQI 5D72A 2R7ZD 1YKBA 1PVHB 1M4AA 3NCFA 2D48A 1INRA 1FG9A 4U4TA 4BBRD 3D85C 5EQIA 3LB6A 1GNCA 4D2DA 5L6YC 1CYLA 4A3ED 1EXZA 1M4RA 2JA5D 3G9VB 4D2CA 1F45B 1QVNA 1HULA 4FA8E 4UVMA 4BBSD 2CYKA 3LB6B 3OQ3A 3HOVD 5A2OA 5D28B 1EKUA 2IL6A 3H0GD 5IYCD 2JA8D 3UEZE 4GRWA 1ITIA 2LAGA 1EVSA 4J05A 2L3OA 1BGCA 1IRLA 1NBPA 3UF5A 1IK0A 2B90A 1IARA 1BUYA 1EMRA 1HWGA 4XNJA 3HMXB 2C35A 3H3VE 1ALUA 2Z3RA 4A3FD 4PS4A 3L5XA 4GC0A 1I1RB 2CFQA 3DUHC 4A3MD 1A7MA 4O9HA 3PO3D 1PV6A 3WCYI 4OAAA 4LDSA 5LQBA 3I4ND 3G6DA 5IYDD 5D6KA 1HIKA 3I4MD 4ZW9A 4NN5A 2INTA 3O7PA 3QT2C 4YQXA 1Y1WD 1ETEA 4JREA 2B8YA 2PSMA 3HOXD 1FYHA 4IKVA 2JA7D 2O26A 5C7XA 3QB7A 1LK3A 4BXXD 5D70A 4YDYI 2B8UA 4BY1D 5EQHA 5C3ED 1BP3A 3WDOA 1RFBA 5FLMD 3IRHA 3DI3A 3L5WI 1RCBA 1BBNA 3BPNA 4OH3A 4NEJA 1P9MB 4YUEC 4IKWA 2L3YA 3SE3B 5TS9A 3PIWA 1A22A 4IU9A 1PV7A 4IKXA 3OG6A 1CSGA 2B8XA 2O6IA 2Q14A 2CFPA 2XQBA 5FHXA 1J7VL 1EERA 5D58A 1M4BA 4A3GD 4IKZA 2D9QA 1Y14A 3BESL 4EXPA 3INKC 2B91A 2VUMD 4APSA 3HHRA 3NPZA 2B63D 1Y6KL 4GS7A 5D59A 2Q7NB 1GA3A 1V7NV 3NCEA 5IYBD 4A3LD 4IKYA 4DKEA 1BGEA 2LMSA 3HOYD 4ZWBA 3HOWD 1Y1VD 5C44D 4NEMA 2OQPA 5IP7D 4WRLB 3D48P 4DKDA 5D22A 3D87A 3MZGA 4A3ID 3SE4B 5EQGA 3QWRB 4JR9A 4Q65A 1WU3I 5D71A 3QAZA 4A3BD 4TPHA 5GXBA 4Z5RD 2Q98A 4IU8A 4XNIA 4ZYRA 3EW3A 1Z7CA 3N0PA 2ILKA 5A2NA 3UF2A 3O7QA 4TPJA 5E4EA 4DKCA 1Y6ML 4TPGA 3TGXB 4GBYA 2H24A 1PY2A 4A3DD 5IP9D 2JA6D 1CD9A 3Q1SI 2B5IA 3BPLA 1BCNA 1IJZA 1ITFA 2HYMB 2Z3QA 4YPGC 3BPOA 4LEPA 1D9GA 4NN6A 3PO2D 4O6KA 4ZWCA 1M47A 3VA2A 1PGRA 3HOZD 1AU1A 4MHLA 1AXIA 4JA3A 3UX9A 1PW4A 3N06A 1CN4C 4X51A 1HIJA 4W6VA 1M48A 1V7MV 1ILKA 1F6FA 4J4LC 2V8NA 1LQSL 4DKFA 3HOUD 4U4VA 1LKIA 4ZS7A 3B5KA 1CNT1 1B5LA 3QB1A 1Y6NL 1ITLA 1M4CA 5C65A 4NKQC 4EXNA 1ITMA 4LRLA 4D2BA 1WCMD 4NI9A 1KF9A 2ERJD 3AYHA 4YBQA 3NCBA 3DGCL 4ZF7A 4A3CD 1VLKA 1RW5A 2O27A 3NCCA 4A3JD 2Y5YA 5C4XD 3PIVA 4NN7A 1SCFA 1AX8A 3OG4A 4GBZA 4CNIC 4A93D 4YB9D 2R92D 1HUWA 1Z92A 3EJJA 3HHCA 1IL6A 2GMFA 1HGUA 4BY7D 4RS1A 4PYPA 2E9WC 3S9DA 5FUCA 4NI7A 2KZ1A 4A3KD 3FKID 4I77Z 1M49A
chains in the Genus database with same CATH topology
1PW4A 2CFQA 4APSA 4ZYRA 2XUTA 2Y5YA 4OH3A 5EQIA 4W6VA 4IKVA 4D2DA 5C65A 4PYPA 1PV6A 4OAAA 5D59A 4IKWA 4LDSA 5EQGA 4JR9A 4U4WA 4QIQA 4Q65A 2CFPA 5A2NA 5A2OA 4IKYA 4D2BA 3O7QA 5D6KA 4XNJA 4TPJA 4LEPA 5D58A 2V8NA 4IKZA 4ZW9A 4D2CA 4U4VA 4GBZA 4J05A 4IU9A 4TPGA 5EQHA 4UVMA 1PV7A 4ZWBA 3O7PA 4ZWCA 4YB9D 4TPHA 4YBQA 5GXBA 4IKXA 3WDOA 4GBYA 4IU8A 4JREA 4JA3A 4XNIA 4U4TA 4GC0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PW4 A;  2CFQ A;  4APS A;  4ZYR A;  2XUT A;  2Y5Y A;  4OH3 A;  5EQI A;  4W6V A;  4IKV A;  4D2D A;  5C65 A;  4PYP A;  1PV6 A;  4OAA A;  5D59 A;  4IKW A;  4LDS A;  5EQG A;  4JR9 A;  4U4W A;  4QIQ A;  4Q65 A;  2CFP A;  5A2N A;  5A2O A;  4IKY A;  4D2B A;  3O7Q A;  5D6K A;  4XNJ A;  4TPJ A;  4LEP A;  5D58 A;  2V8N A;  4IKZ A;  4ZW9 A;  4D2C A;  4U4V A;  4GBZ A;  4J05 A;  4IU9 A;  4TPG A;  5EQH A;  4UVM A;  1PV7 A;  4ZWB A;  3O7P A;  4ZWC A;  4YB9 D;  4TPH A;  4YBQ A;  5GXB A;  4IKX A;  3WDO A;  4GBY A;  4IU8 A;  4JRE A;  4JA3 A;  4XNI A;  4U4T A;  4GC0 A; 
#chains in the Genus database with same CATH topology
 1N1F A;  2XUT A;  1HZI A;  1JLI A;  5KNH I;  4U4W A;  4DOH A;  4QIQ A;  3DI2 A;  1D9C A;  2R93 D;  2B8Z A;  1PW6 A;  1BGD A;  1HWH A;  1RHG A;  3DLQ I;  5D72 A;  2R7Z D;  1YKB A;  1PVH B;  1M4A A;  3NCF A;  2D48 A;  1INR A;  1FG9 A;  4U4T A;  4BBR D;  3D85 C;  5EQI A;  3LB6 A;  1GNC A;  4D2D A;  5L6Y C;  1CYL A;  4A3E D;  1EXZ A;  1M4R A;  2JA5 D;  3G9V B;  4D2C A;  1F45 B;  1QVN A;  1HUL A;  4FA8 E;  4UVM A;  4BBS D;  2CYK A;  3LB6 B;  3OQ3 A;  3HOV D;  5A2O A;  5D28 B;  1EKU A;  2IL6 A;  3H0G D;  5IYC D;  2JA8 D;  3UEZ E;  4GRW A;  1ITI A;  2LAG A;  1EVS A;  4J05 A;  2L3O A;  1BGC A;  1IRL A;  1NBP A;  3UF5 A;  1IK0 A;  2B90 A;  1IAR A;  1BUY A;  1EMR A;  1HWG A;  4XNJ A;  3HMX B;  2C35 A;  3H3V E;  1ALU A;  2Z3R A;  4A3F D;  4PS4 A;  3L5X A;  4GC0 A;  1I1R B;  2CFQ A;  3DUH C;  4A3M D;  1A7M A;  4O9H A;  3PO3 D;  1PV6 A;  3WCY I;  4OAA A;  4LDS A;  5LQB A;  3I4N D;  3G6D A;  5IYD D;  5D6K A;  1HIK A;  3I4M D;  4ZW9 A;  4NN5 A;  2INT A;  3O7P A;  3QT2 C;  4YQX A;  1Y1W D;  1ETE A;  4JRE A;  2B8Y A;  2PSM A;  3HOX D;  1FYH A;  4IKV A;  2JA7 D;  2O26 A;  5C7X A;  3QB7 A;  1LK3 A;  4BXX D;  5D70 A;  4YDY I;  2B8U A;  4BY1 D;  5EQH A;  5C3E D;  1BP3 A;  3WDO A;  1RFB A;  5FLM D;  3IRH A;  3DI3 A;  3L5W I;  1RCB A;  1BBN A;  3BPN A;  4OH3 A;  4NEJ A;  1P9M B;  4YUE C;  4IKW A;  2L3Y A;  3SE3 B;  5TS9 A;  3PIW A;  1A22 A;  4IU9 A;  1PV7 A;  4IKX A;  3OG6 A;  1CSG A;  2B8X A;  2O6I A;  2Q14 A;  2CFP A;  2XQB A;  5FHX A;  1J7V L;  1EER A;  5D58 A;  1M4B A;  4A3G D;  4IKZ A;  2D9Q A;  1Y14 A;  3BES L;  4EXP A;  3INK C;  2B91 A;  2VUM D;  4APS A;  3HHR A;  3NPZ A;  2B63 D;  1Y6K L;  4GS7 A;  5D59 A;  2Q7N B;  1GA3 A;  1V7N V;  3NCE A;  5IYB D;  4A3L D;  4IKY A;  4DKE A;  1BGE A;  2LMS A;  3HOY D;  4ZWB A;  3HOW D;  1Y1V D;  5C44 D;  4NEM A;  2OQP A;  5IP7 D;  4WRL B;  3D48 P;  4DKD A;  5D22 A;  3D87 A;  3MZG A;  4A3I D;  3SE4 B;  5EQG A;  3QWR B;  4JR9 A;  4Q65 A;  1WU3 I;  5D71 A;  3QAZ A;  4A3B D;  4TPH A;  5GXB A;  4Z5R D;  2Q98 A;  4IU8 A;  4XNI A;  4ZYR A;  3EW3 A;  1Z7C A;  3N0P A;  2ILK A;  5A2N A;  3UF2 A;  3O7Q A;  4TPJ A;  5E4E A;  4DKC A;  1Y6M L;  4TPG A;  3TGX B;  4GBY A;  2H24 A;  1PY2 A;  4A3D D;  5IP9 D;  2JA6 D;  1CD9 A;  3Q1S I;  2B5I A;  3BPL A;  1BCN A;  1IJZ A;  1ITF A;  2HYM B;  2Z3Q A;  4YPG C;  3BPO A;  4LEP A;  1D9G A;  4NN6 A;  3PO2 D;  4O6K A;  4ZWC A;  1M47 A;  3VA2 A;  1PGR A;  3HOZ D;  1AU1 A;  4MHL A;  1AXI A;  4JA3 A;  3UX9 A;  1PW4 A;  3N06 A;  1CN4 C;  4X51 A;  1HIJ A;  4W6V A;  1M48 A;  1V7M V;  1ILK A;  1F6F A;  4J4L C;  2V8N A;  1LQS L;  4DKF A;  3HOU D;  4U4V A;  1LKI A;  4ZS7 A;  3B5K A;  1CNT 1;  1B5L A;  3QB1 A;  1Y6N L;  1ITL A;  1M4C A;  5C65 A;  4NKQ C;  4EXN A;  1ITM A;  4LRL A;  4D2B A;  1WCM D;  4NI9 A;  1KF9 A;  2ERJ D;  3AYH A;  4YBQ A;  3NCB A;  3DGC L;  4ZF7 A;  4A3C D;  1VLK A;  1RW5 A;  2O27 A;  3NCC A;  4A3J D;  2Y5Y A;  5C4X D;  3PIV A;  4NN7 A;  1SCF A;  1AX8 A;  3OG4 A;  4GBZ A;  4CNI C;  4A93 D;  4YB9 D;  2R92 D;  1HUW A;  1Z92 A;  3EJJ A;  3HHC A;  1IL6 A;  2GMF A;  1HGU A;  4BY7 D;  4RS1 A;  4PYP A;  2E9W C;  3S9D A;  5FUC A;  4NI7 A;  2KZ1 A;  4A3K D;  3FKI D;  4I77 Z;  1M49 A; 
#chains in the Genus database with same CATH homology
 1PW4 A;  2CFQ A;  4APS A;  4ZYR A;  2XUT A;  2Y5Y A;  4OH3 A;  5EQI A;  4W6V A;  4IKV A;  4D2D A;  5C65 A;  4PYP A;  1PV6 A;  4OAA A;  5D59 A;  4IKW A;  4LDS A;  5EQG A;  4JR9 A;  4U4W A;  4QIQ A;  4Q65 A;  2CFP A;  5A2N A;  5A2O A;  4IKY A;  4D2B A;  3O7Q A;  5D6K A;  4XNJ A;  4TPJ A;  4LEP A;  5D58 A;  2V8N A;  4IKZ A;  4ZW9 A;  4D2C A;  4U4V A;  4GBZ A;  4J05 A;  4IU9 A;  4TPG A;  5EQH A;  4UVM A;  1PV7 A;  4ZWB A;  3O7P A;  4ZWC A;  4YB9 D;  4TPH A;  4YBQ A;  5GXB A;  4IKX A;  3WDO A;  4GBY A;  4IU8 A;  4JRE A;  4JA3 A;  4XNI A;  4U4T A;  4GC0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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