4IYCA

Structure of the t244a mutant of the panton-valentine leucocidin component from staphylococcus aureus
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
283
structure length
277
Chain Sequence
NNIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords LukS-PV
publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
source organism Staphylococcus phage pvl
total genus 67
structure length 277
sequence length 283
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4iycA00
3M4DA 3LKFA 4IYTA 4P1YB 4P1YA 3M4EA 5K59C 1PVLA 4YHDA 3M2LA 1LKFA 1T5RA 4IZLA 3ROHA 3M3RA 4I0NA 4IYCA 3ANZA 4IDJA 3O44A 5K59A 4H56A 2QK7B 2QK7A 4IYAA 2YGTA 3B07B 3B07A 4P24A 4TW1B 4TW1A 4U6VA 4P1XB 2LKFA 4P1XA 7AHLA 4Q7GA 4J0OA
chains in the Genus database with same CATH superfamily
3M4DA 3LKFA 4IYTA 4P1YB 4P1YA 3M4EA 5K59C 1PVLA 4YHDA 3M2LA 1LKFA 1T5RA 4IZLA 3ROHA 3M3RA 4I0NA 4IYCA 3ANZA 4IDJA 3O44A 5K59A 4H56A 2QK7B 2QK7A 4IYAA 2YGTA 3B07B 3B07A 4P24A 4TW1B 4TW1A 4U6VA 4P1XB 2LKFA 4P1XA 7AHLA 1XEZA 4Q7GA 4J0OA
chains in the Genus database with same CATH topology
3M4DA 3LKFA 4IYTA 4P1YB 4P1YA 3M4EA 5K59C 1PVLA 4YHDA 3M2LA 1LKFA 1T5RA 4IZLA 3ROHA 3M3RA 4I0NA 4IYCA 3ANZA 4IDJA 3O44A 5K59A 4H56A 2QK7B 2QK7A 4IYAA 2YGTA 3B07B 3B07A 4P24A 4TW1B 4TW1A 4U6VA 4P1XB 2LKFA 4P1XA 7AHLA 4Q7GA 4J0OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M4D A;  3LKF A;  4IYT A;  4P1Y B;  4P1Y A;  3M4E A;  5K59 C;  1PVL A;  4YHD A;  3M2L A;  1LKF A;  1T5R A;  4IZL A;  3ROH A;  3M3R A;  4I0N A;  4IYC A;  3ANZ A;  4IDJ A;  3O44 A;  5K59 A;  4H56 A;  2QK7 B;  2QK7 A;  4IYA A;  2YGT A;  3B07 B;  3B07 A;  4P24 A;  4TW1 B;  4TW1 A;  4U6V A;  4P1X B;  2LKF A;  4P1X A;  7AHL A;  4Q7G A;  4J0O A; 
#chains in the Genus database with same CATH topology
 3M4D A;  3LKF A;  4IYT A;  4P1Y B;  4P1Y A;  3M4E A;  5K59 C;  1PVL A;  4YHD A;  3M2L A;  1LKF A;  1T5R A;  4IZL A;  3ROH A;  3M3R A;  4I0N A;  4IYC A;  3ANZ A;  4IDJ A;  3O44 A;  5K59 A;  4H56 A;  2QK7 B;  2QK7 A;  4IYA A;  2YGT A;  3B07 B;  3B07 A;  4P24 A;  4TW1 B;  4TW1 A;  4U6V A;  4P1X B;  2LKF A;  4P1X A;  7AHL A;  1XEZ A;  4Q7G A;  4J0O A; 
#chains in the Genus database with same CATH homology
 3M4D A;  3LKF A;  4IYT A;  4P1Y B;  4P1Y A;  3M4E A;  5K59 C;  1PVL A;  4YHD A;  3M2L A;  1LKF A;  1T5R A;  4IZL A;  3ROH A;  3M3R A;  4I0N A;  4IYC A;  3ANZ A;  4IDJ A;  3O44 A;  5K59 A;  4H56 A;  2QK7 B;  2QK7 A;  4IYA A;  2YGT A;  3B07 B;  3B07 A;  4P24 A;  4TW1 B;  4TW1 A;  4U6V A;  4P1X B;  2LKF A;  4P1X A;  7AHL A;  4Q7G A;  4J0O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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