4J0OA

Structure of the y246a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
282
structure length
275
Chain Sequence
NIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTAGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords LukS-PV
publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
source organism Staphylococcus phage pvl
total genus 72
structure length 275
sequence length 282
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4j0oA00
1PVLA 4IYTA 4P1XB 5K59C 4YHDA 3B07B 1T5RA 3ANZA 2YGTA 1LKFA 4P24A 4TW1A 2QK7A 4I0NA 4IYAA 4Q7GA 4J0OA 3LKFA 4IYCA 4U6VA 4P1YA 4IDJA 3O44A 4TW1B 2QK7B 4IZLA 2LKFA 4P1XA 3M4DA 3ROHA 3B07A 4H56A 5K59A 3M4EA 3M2LA 4P1YB 3M3RA 7AHLA
chains in the Genus database with same CATH superfamily
1PVLA 4IYTA 4P1XB 5K59C 4YHDA 3B07B 1T5RA 3ANZA 2YGTA 1LKFA 4P24A 4TW1A 2QK7A 4I0NA 4IYAA 4Q7GA 4J0OA 1XEZA 3LKFA 4IYCA 4U6VA 4P1YA 4IDJA 3O44A 4TW1B 2QK7B 4IZLA 2LKFA 4P1XA 3M4DA 3ROHA 3B07A 4H56A 5K59A 3M4EA 3M2LA 4P1YB 3M3RA 7AHLA
chains in the Genus database with same CATH topology
1PVLA 4IYTA 4P1XB 5K59C 4YHDA 3B07B 1T5RA 3ANZA 2YGTA 1LKFA 4P24A 4TW1A 2QK7A 4I0NA 4IYAA 4Q7GA 4J0OA 3LKFA 4IYCA 4U6VA 4P1YA 4IDJA 3O44A 4TW1B 2QK7B 4IZLA 2LKFA 4P1XA 3M4DA 3ROHA 3B07A 4H56A 5K59A 3M4EA 3M2LA 4P1YB 3M3RA 7AHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVL A;  4IYT A;  4P1X B;  5K59 C;  4YHD A;  3B07 B;  1T5R A;  3ANZ A;  2YGT A;  1LKF A;  4P24 A;  4TW1 A;  2QK7 A;  4I0N A;  4IYA A;  4Q7G A;  4J0O A;  3LKF A;  4IYC A;  4U6V A;  4P1Y A;  4IDJ A;  3O44 A;  4TW1 B;  2QK7 B;  4IZL A;  2LKF A;  4P1X A;  3M4D A;  3ROH A;  3B07 A;  4H56 A;  5K59 A;  3M4E A;  3M2L A;  4P1Y B;  3M3R A;  7AHL A; 
#chains in the Genus database with same CATH topology
 1PVL A;  4IYT A;  4P1X B;  5K59 C;  4YHD A;  3B07 B;  1T5R A;  3ANZ A;  2YGT A;  1LKF A;  4P24 A;  4TW1 A;  2QK7 A;  4I0N A;  4IYA A;  4Q7G A;  4J0O A;  1XEZ A;  3LKF A;  4IYC A;  4U6V A;  4P1Y A;  4IDJ A;  3O44 A;  4TW1 B;  2QK7 B;  4IZL A;  2LKF A;  4P1X A;  3M4D A;  3ROH A;  3B07 A;  4H56 A;  5K59 A;  3M4E A;  3M2L A;  4P1Y B;  3M3R A;  7AHL A; 
#chains in the Genus database with same CATH homology
 1PVL A;  4IYT A;  4P1X B;  5K59 C;  4YHD A;  3B07 B;  1T5R A;  3ANZ A;  2YGT A;  1LKF A;  4P24 A;  4TW1 A;  2QK7 A;  4I0N A;  4IYA A;  4Q7G A;  4J0O A;  3LKF A;  4IYC A;  4U6V A;  4P1Y A;  4IDJ A;  3O44 A;  4TW1 B;  2QK7 B;  4IZL A;  2LKF A;  4P1X A;  3M4D A;  3ROH A;  3B07 A;  4H56 A;  5K59 A;  3M4E A;  3M2L A;  4P1Y B;  3M3R A;  7AHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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