4J3DA

Pseudomonas aeruginosa lpxc in complex with a hydroxamate inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
297
structure length
287
Chain Sequence
b'MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYM'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Exploring the UDP pocket of LpxC through amino acid analogs.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
total genus 84
structure length 287
sequence length 297
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4j3dA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4j3dA02
1P42A 4FW6A 5DROA 4IS9A 4U3DA 3P76A 4FW3A 4U3BA 5DRPA 4FW5A 2GO4A 2JT2A 2IERA 3UHMA 4MDTA 3P3GA 3PS2A 4LCFA 4ISAA 3P3EA 4FW7A 3PS3A 3PS1A 2O3ZA 4J3DA 4LCHA 1XXEA 4FW4A 1YHCA 5DRQA 4OZEA 4LCGA 3NZKA 5DRRA 3P3CA 1YH8A 2GO3A 2J65A 2VESA 4MQYA 2IESA 3U1YA 4OKGA
chains in the Genus database with same CATH superfamily
1KTVA 2XEXA 1ZXNA 3K1JA 4FN5A 2UXDE 1EI1A 4MYTA 1HNXI 3PS2A 2O1TA 1FJGE 1N0UA 2O1WA 2WW4A 5C0XC 5LMNE 4DUZI 4DR1I 4X62E 1XHKA 4LF8E 4JI1I 1E3PA 3H1CA 2IOPA 2CGEA 2PO2B 1J5EI 2BA0D 5DRRA 3P3CA 4DU8A 4JI2I 4JV5I 4DPYA 1VISA 2J65A 1R6MA 1H72C 4DPWA 1KKHA 4FWDA 1S16A 4OO1B 4QNJA 4FW6A 3M85G 1PIEA 4URLA 4DR7E 2HFUA 5IWAE 4DV6E 2C39B 1R6LA 3M85D 4K0KI 1K47A 5K36C 2Z5EA 5DNXA 4JI5I 2PO1A 4OO1F 1ZM9A 3B8HA 4M1KA 1Z0GA 4X64E 1I94E 5GMDA 2BM0A 4MU4A 4DV0E 5LMUE 4BA2A 4JI4E 4OO1E 2UUCI 3QT5A 2Z5BA 3ZKDA 4DXLA 3GCMA 4N3OA 4NBQA 2V2ZA 1HNZE 4HY1A 5LL6R 3ZM7A 4DPUA 4DV6I 4MDTA 4MU0A 3ZZ0A 4JI6I 3P3EA 3JAMQ 4IFDD 4LF6I 1UEKA 5JEAB 2UU9E 4YHHI 2PNMA 1XMOE 4X64I 1Z59A 2VQFE 4DV0I 1FKAE 4HACB 2GS8A 4B3RE 4P7AA 4LFCE 4DR6I 3WU6A 5JEAF 4AM3A 2HK3A 4ZVIA 4DR2E 1HNZI 3J7AG 1Z5BA 4LF4E 4PRXA 5BR8E 1N34I 2UUBE 2F1DA 1NHJA 1USUA 4DV7E 2IERA 5JEAE 3T1YE 4DV2I 1Z0VA 4DV3E 3PYEA 2EFGA 5C0XA 4LFBE 4DV4I 4JI8I 2VQFI 3U1KA 4KQVA 4B3RI 1YHCA 1UDOA 2F4VE 4R1FA 2V8PA 2PO0A 2PNLA 4USKA 2V34A 3CDJA 4DR3E 3LPSA 4B3SE 2V2VA 4AQYE 1XNQE 4YY3I 4I3HA 1Z0CA 2UUAE 2BA1D 2R42A 2NN6B 1RR9A 4HYMA 4LF7I 4OX9I 4X65E 2NN6F 3J7AM 2AE8A 3OTOE 1EA6A 2IOQA 1Y4SA 2Z5CA 2R3VA 3CDIA 4B3SI 1B63A 4UTGA 4LF9E 1FI4A 2PNZA 2NN6E 4X66I 2IESA 1HR0E 4BA1A 4DR5E 1P42A 3LTOA 1OYSA 5DROA 2BR2B 1VI7A 3PRYA 5GMEA 3QT7A 2X7IA 3H4LA 3Q6NA 4PRVA 4FW7A 4FWGA 3ZZTA 4UT4A 2V2QA 2JEBA 5C0XB 4DPTA 1PKPA 2BA0G 1KVKA 2UXCE 4WUDA 1HR0I 4DV5E 1MU5A 3L7ZA 4LOMA 2HHHE 3D4JA 2UXDI 2C37B 3P06A 3JAMC 3P3GA 1Z0WA 5C0XE 5K36B 4P52A 4ISAA 1FJGI 4AIMA 5LMNI 3B4TA 5EKWA 1XNRE 1B62A 4X62I 1U2RA 4MU1A 4LF8I 1FWLA 3V5RA 4DPXA 5K36F 2O1UA 4MU3A 4LCGA 2JEAB 4IZJA 5FLXC 3DD6A 2DEJA 2WP8A 4JI3E 2LJPA 1OYRA 5K36E 1S4EA 4DR7I 5IWAI 4B3ME 4OO1D 4IFDC 2WNRA 1WUUA 4JI0E 2E5LE 1Y5YA 1MX0A 2O1VA 2C38A 4DR4E 1I94I 1ZM4A 5LMUI 4DV1E 4OZEA 4JI4I 2GO3A 2NPFA 4NXNE 2BM1A 4AIDA 1N32E 3GLLA 3U1YA 2ZM6E 3L7ZB 1Z0TA 1N0VC 5FLXQ 4B3MI 4JYAE 4IS9A 4U3DA 3B78A 1BKNA 3P76A 2JT2A 4DUYE 2X36A 1ZXMA 1HNWE 1ELOA 1Y4UA 2E5LI 2UU9I 2HK2A 5IT9Q 1XMOI 4DR4I 2PO1B 4J3DA 3K17A 4LCHA 4JI7E 5JEAD 4DV1I 1N33E 1E3HA 4LFCI 4NXNI 3HULA 1Y60A 4FW9A 2BA1G 4DR2I 4IZJB 4BA2B 4LF4I 3V2UC 4OKGA 1KIJA 5BR8I 2UUBI 2AJ4A 4GKJE 2Z5BB 3GONA 4DV7I 3KRNA 2VQEE 4WUBA 1USVA 3T1YI 1HNWI 4DV3I 3F0NA 3LNUA 3WU3A 4LFBI 2WNRB 2Q2EB 1RREA 5A2QC 2O3ZA 2F4VI 1XMQE 1HK7A 1Y6ZA 1ZM2A 2C38B 4DR3I 5L3JA 2CG9A 4LF5E 4OO1A 4AQYI 4B3TE 1N36E 1XNQI 2GQ0A 2HFSA 4MQYA 1IBKE 5EL9A 1UDNA 2UUAI 2C39A 3WU5A 4KHPE 2HKJA 4IFDA 5DRPA 4NXME 4FW5A 4PU9A 3J81C 3UHMA 2NN6D 4X65I 1HNXE 3Q1QA 4LCFA 3PS3A 3M7ND 3QT8A 2JE6A 4LPFA 3OTOI 1QZRA 4DR1E 1UDSA 1Z5CA 5DRQA 4JI1E 4HXZA 5A2QQ 1J5EE 4LF9I 4RPFA 1UDQA 4JI2E 4JV5E 2PO0B 4DR5I 5C0XF 1DARA 2OI2A 4XTJA 4NXMI 4QNKA 1ZM3A 1OYPA 3ZZUA 3PYGA 5JEAA 3T1HE 4Z7CA 4K0KE 3B82A 4JI5E 3J81Q 4HACA 3ZKBA 2HKEA 1FNMA 4MYUA 2UXCI 4FW4A 5C0XD 2BV3A 4DV5I 3PYDA 2Z5CB 1H7SA 1NHIA 2UUCE 4OO1C 2DEIA 2HHHI 2PNZB 2CZ9A 4BA1B 3T1HI 4IFDB 5IT9C 2ZBKB 4GKKE 4IZKA 4JI6E 1XNRI 3HKMA 4LF6E 5K36D 3J80C 4YHHE 3M6AA 4IFDF 2JE6B 4Z7YA 2JEBB 1IBLE 4DR6E 2NN6A 4EMDA 4JI3I 4IFDE 3WU4A 4FW3A 4JG4A 1N34E 4GKKI 4DV2E 4JI0I 5JEAC 4DV4E 3GMEA 4JI8E 1IBLI 1XXEA 4GQUA 1H73A 3PYFA 1NHHA 3NZKA 3J80Q 1YH8A 2A2DA 2VF3A 2BR2A 1N32I 2ZM6I 4YY3E 4JYAI 2CVEA 1IBME 2WP8B 1A6FA 4U3BA 4DUYI 4LF7E 4OX9E 1Z5AA 1MG7A 1D6TA 3CWVA 1OJ4A 4DU7A 1NZ0A 4IZKB 4JI7I 1H74A 2PO2A 1N33I 3QT6A 3HJCA 4WUCA 1RHYA 1Z0BA 2J7KA 4FWHA 5FWKA 4LFAE 2E1RA 1IBMI 4X66E 2C37A 3Q6MA 2UXBE 4ED4A 4GKJI 4IZJD 2NN6C 2VQEI 5K36A 2GO4A 1H7UA 3M7NG 5ELWA 2ZITA 3PS1A 3K85A 2JEAA 4DUZE 1XMQI 5DNLA 4LFAI 1Z0EA 1FWKA 4LF5I 2A2CA 4B3TI 1N36I 4USMA 1IBKI 2UXBI 2VESA 1PVGA 4KHPI
chains in the Genus database with same CATH topology
1P42A 4FW6A 5DROA 4IS9A 4U3DA 3P76A 4FW3A 4U3BA 5DRPA 4FW5A 2GO4A 2JT2A 2IERA 3UHMA 4MDTA 3P3GA 3PS2A 4LCFA 4ISAA 3P3EA 4FW7A 3PS3A 3PS1A 2O3ZA 4J3DA 4LCHA 1XXEA 4FW4A 1YHCA 5DRQA 4OZEA 4LCGA 3NZKA 5DRRA 3P3CA 1YH8A 2GO3A 2J65A 2VESA 4MQYA 2IESA 3U1YA 4OKGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P42 A;  4FW6 A;  5DRO A;  4IS9 A;  4U3D A;  3P76 A;  4FW3 A;  4U3B A;  5DRP A;  4FW5 A;  2GO4 A;  2JT2 A;  2IER A;  3UHM A;  4MDT A;  3P3G A;  3PS2 A;  4LCF A;  4ISA A;  3P3E A;  4FW7 A;  3PS3 A;  3PS1 A;  2O3Z A;  4J3D A;  4LCH A;  1XXE A;  4FW4 A;  1YHC A;  5DRQ A;  4OZE A;  4LCG A;  3NZK A;  5DRR A;  3P3C A;  1YH8 A;  2GO3 A;  2J65 A;  2VES A;  4MQY A;  2IES A;  3U1Y A;  4OKG A; 
#chains in the Genus database with same CATH topology
 1KTV A;  2XEX A;  1ZXN A;  3K1J A;  4FN5 A;  2UXD E;  1EI1 A;  4MYT A;  1HNX I;  3PS2 A;  2O1T A;  1FJG E;  1N0U A;  2O1W A;  2WW4 A;  5C0X C;  5LMN E;  4DUZ I;  4DR1 I;  4X62 E;  1XHK A;  4LF8 E;  4JI1 I;  1E3P A;  3H1C A;  2IOP A;  2CGE A;  2PO2 B;  1J5E I;  2BA0 D;  5DRR A;  3P3C A;  4DU8 A;  4JI2 I;  4JV5 I;  4DPY A;  1VIS A;  2J65 A;  1R6M A;  1H72 C;  4DPW A;  1KKH A;  4FWD A;  1S16 A;  4OO1 B;  4QNJ A;  4FW6 A;  3M85 G;  1PIE A;  4URL A;  4DR7 E;  2HFU A;  5IWA E;  4DV6 E;  2C39 B;  1R6L A;  3M85 D;  4K0K I;  1K47 A;  5K36 C;  2Z5E A;  5DNX A;  4JI5 I;  2PO1 A;  4OO1 F;  1ZM9 A;  3B8H A;  4M1K A;  1Z0G A;  4X64 E;  1I94 E;  5GMD A;  2BM0 A;  4MU4 A;  4DV0 E;  5LMU E;  4BA2 A;  4JI4 E;  4OO1 E;  2UUC I;  3QT5 A;  2Z5B A;  3ZKD A;  4DXL A;  3GCM A;  4N3O A;  4NBQ A;  2V2Z A;  1HNZ E;  4HY1 A;  5LL6 R;  3ZM7 A;  4DPU A;  4DV6 I;  4MDT A;  4MU0 A;  3ZZ0 A;  4JI6 I;  3P3E A;  3JAM Q;  4IFD D;  4LF6 I;  1UEK A;  5JEA B;  2UU9 E;  4YHH I;  2PNM A;  1XMO E;  4X64 I;  1Z59 A;  2VQF E;  4DV0 I;  1FKA E;  4HAC B;  2GS8 A;  4B3R E;  4P7A A;  4LFC E;  4DR6 I;  3WU6 A;  5JEA F;  4AM3 A;  2HK3 A;  4ZVI A;  4DR2 E;  1HNZ I;  3J7A G;  1Z5B A;  4LF4 E;  4PRX A;  5BR8 E;  1N34 I;  2UUB E;  2F1D A;  1NHJ A;  1USU A;  4DV7 E;  2IER A;  5JEA E;  3T1Y E;  4DV2 I;  1Z0V A;  4DV3 E;  3PYE A;  2EFG A;  5C0X A;  4LFB E;  4DV4 I;  4JI8 I;  2VQF I;  3U1K A;  4KQV A;  4B3R I;  1YHC A;  1UDO A;  2F4V E;  4R1F A;  2V8P A;  2PO0 A;  2PNL A;  4USK A;  2V34 A;  3CDJ A;  4DR3 E;  3LPS A;  4B3S E;  2V2V A;  4AQY E;  1XNQ E;  4YY3 I;  4I3H A;  1Z0C A;  2UUA E;  2BA1 D;  2R42 A;  2NN6 B;  1RR9 A;  4HYM A;  4LF7 I;  4OX9 I;  4X65 E;  2NN6 F;  3J7A M;  2AE8 A;  3OTO E;  1EA6 A;  2IOQ A;  1Y4S A;  2Z5C A;  2R3V A;  3CDI A;  4B3S I;  1B63 A;  4UTG A;  4LF9 E;  1FI4 A;  2PNZ A;  2NN6 E;  4X66 I;  2IES A;  1HR0 E;  4BA1 A;  4DR5 E;  1P42 A;  3LTO A;  1OYS A;  5DRO A;  2BR2 B;  1VI7 A;  3PRY A;  5GME A;  3QT7 A;  2X7I A;  3H4L A;  3Q6N A;  4PRV A;  4FW7 A;  4FWG A;  3ZZT A;  4UT4 A;  2V2Q A;  2JEB A;  5C0X B;  4DPT A;  1PKP A;  2BA0 G;  1KVK A;  2UXC E;  4WUD A;  1HR0 I;  4DV5 E;  1MU5 A;  3L7Z A;  4LOM A;  2HHH E;  3D4J A;  2UXD I;  2C37 B;  3P06 A;  3JAM C;  3P3G A;  1Z0W A;  5C0X E;  5K36 B;  4P52 A;  4ISA A;  1FJG I;  4AIM A;  5LMN I;  3B4T A;  5EKW A;  1XNR E;  1B62 A;  4X62 I;  1U2R A;  4MU1 A;  4LF8 I;  1FWL A;  3V5R A;  4DPX A;  5K36 F;  2O1U A;  4MU3 A;  4LCG A;  2JEA B;  4IZJ A;  5FLX C;  3DD6 A;  2DEJ A;  2WP8 A;  4JI3 E;  2LJP A;  1OYR A;  5K36 E;  1S4E A;  4DR7 I;  5IWA I;  4B3M E;  4OO1 D;  4IFD C;  2WNR A;  1WUU A;  4JI0 E;  2E5L E;  1Y5Y A;  1MX0 A;  2O1V A;  2C38 A;  4DR4 E;  1I94 I;  1ZM4 A;  5LMU I;  4DV1 E;  4OZE A;  4JI4 I;  2GO3 A;  2NPF A;  4NXN E;  2BM1 A;  4AID A;  1N32 E;  3GLL A;  3U1Y A;  2ZM6 E;  3L7Z B;  1Z0T A;  1N0V C;  5FLX Q;  4B3M I;  4JYA E;  4IS9 A;  4U3D A;  3B78 A;  1BKN A;  3P76 A;  2JT2 A;  4DUY E;  2X36 A;  1ZXM A;  1HNW E;  1ELO A;  1Y4U A;  2E5L I;  2UU9 I;  2HK2 A;  5IT9 Q;  1XMO I;  4DR4 I;  2PO1 B;  4J3D A;  3K17 A;  4LCH A;  4JI7 E;  5JEA D;  4DV1 I;  1N33 E;  1E3H A;  4LFC I;  4NXN I;  3HUL A;  1Y60 A;  4FW9 A;  2BA1 G;  4DR2 I;  4IZJ B;  4BA2 B;  4LF4 I;  3V2U C;  4OKG A;  1KIJ A;  5BR8 I;  2UUB I;  2AJ4 A;  4GKJ E;  2Z5B B;  3GON A;  4DV7 I;  3KRN A;  2VQE E;  4WUB A;  1USV A;  3T1Y I;  1HNW I;  4DV3 I;  3F0N A;  3LNU A;  3WU3 A;  4LFB I;  2WNR B;  2Q2E B;  1RRE A;  5A2Q C;  2O3Z A;  2F4V I;  1XMQ E;  1HK7 A;  1Y6Z A;  1ZM2 A;  2C38 B;  4DR3 I;  5L3J A;  2CG9 A;  4LF5 E;  4OO1 A;  4AQY I;  4B3T E;  1N36 E;  1XNQ I;  2GQ0 A;  2HFS A;  4MQY A;  1IBK E;  5EL9 A;  1UDN A;  2UUA I;  2C39 A;  3WU5 A;  4KHP E;  2HKJ A;  4IFD A;  5DRP A;  4NXM E;  4FW5 A;  4PU9 A;  3J81 C;  3UHM A;  2NN6 D;  4X65 I;  1HNX E;  3Q1Q A;  4LCF A;  3PS3 A;  3M7N D;  3QT8 A;  2JE6 A;  4LPF A;  3OTO I;  1QZR A;  4DR1 E;  1UDS A;  1Z5C A;  5DRQ A;  4JI1 E;  4HXZ A;  5A2Q Q;  1J5E E;  4LF9 I;  4RPF A;  1UDQ A;  4JI2 E;  4JV5 E;  2PO0 B;  4DR5 I;  5C0X F;  1DAR A;  2OI2 A;  4XTJ A;  4NXM I;  4QNK A;  1ZM3 A;  1OYP A;  3ZZU A;  3PYG A;  5JEA A;  3T1H E;  4Z7C A;  4K0K E;  3B82 A;  4JI5 E;  3J81 Q;  4HAC A;  3ZKB A;  2HKE A;  1FNM A;  4MYU A;  2UXC I;  4FW4 A;  5C0X D;  2BV3 A;  4DV5 I;  3PYD A;  2Z5C B;  1H7S A;  1NHI A;  2UUC E;  4OO1 C;  2DEI A;  2HHH I;  2PNZ B;  2CZ9 A;  4BA1 B;  3T1H I;  4IFD B;  5IT9 C;  2ZBK B;  4GKK E;  4IZK A;  4JI6 E;  1XNR I;  3HKM A;  4LF6 E;  5K36 D;  3J80 C;  4YHH E;  3M6A A;  4IFD F;  2JE6 B;  4Z7Y A;  2JEB B;  1IBL E;  4DR6 E;  2NN6 A;  4EMD A;  4JI3 I;  4IFD E;  3WU4 A;  4FW3 A;  4JG4 A;  1N34 E;  4GKK I;  4DV2 E;  4JI0 I;  5JEA C;  4DV4 E;  3GME A;  4JI8 E;  1IBL I;  1XXE A;  4GQU A;  1H73 A;  3PYF A;  1NHH A;  3NZK A;  3J80 Q;  1YH8 A;  2A2D A;  2VF3 A;  2BR2 A;  1N32 I;  2ZM6 I;  4YY3 E;  4JYA I;  2CVE A;  1IBM E;  2WP8 B;  1A6F A;  4U3B A;  4DUY I;  4LF7 E;  4OX9 E;  1Z5A A;  1MG7 A;  1D6T A;  3CWV A;  1OJ4 A;  4DU7 A;  1NZ0 A;  4IZK B;  4JI7 I;  1H74 A;  2PO2 A;  1N33 I;  3QT6 A;  3HJC A;  4WUC A;  1RHY A;  1Z0B A;  2J7K A;  4FWH A;  5FWK A;  4LFA E;  2E1R A;  1IBM I;  4X66 E;  2C37 A;  3Q6M A;  2UXB E;  4ED4 A;  4GKJ I;  4IZJ D;  2NN6 C;  2VQE I;  5K36 A;  2GO4 A;  1H7U A;  3M7N G;  5ELW A;  2ZIT A;  3PS1 A;  3K85 A;  2JEA A;  4DUZ E;  1XMQ I;  5DNL A;  4LFA I;  1Z0E A;  1FWK A;  4LF5 I;  2A2C A;  4B3T I;  1N36 I;  4USM A;  1IBK I;  2UXB I;  2VES A;  1PVG A;  4KHP I; 
#chains in the Genus database with same CATH homology
 1P42 A;  4FW6 A;  5DRO A;  4IS9 A;  4U3D A;  3P76 A;  4FW3 A;  4U3B A;  5DRP A;  4FW5 A;  2GO4 A;  2JT2 A;  2IER A;  3UHM A;  4MDT A;  3P3G A;  3PS2 A;  4LCF A;  4ISA A;  3P3E A;  4FW7 A;  3PS3 A;  3PS1 A;  2O3Z A;  4J3D A;  4LCH A;  1XXE A;  4FW4 A;  1YHC A;  5DRQ A;  4OZE A;  4LCG A;  3NZK A;  5DRR A;  3P3C A;  1YH8 A;  2GO3 A;  2J65 A;  2VES A;  4MQY A;  2IES A;  3U1Y A;  4OKG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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