4J3DA

Pseudomonas aeruginosa lpxc in complex with a hydroxamate inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
297
structure length
287
Chain Sequence
b'MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYM'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa
publication title Exploring the UDP pocket of LpxC through amino acid analogs.
pubmed doi rcsb
total genus 84
structure length 287
sequence length 297
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4j3dA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4j3dA02
4MDTA 3U1YA 4FW6A 4LCGA 1YH8A 4U3DA 5DRRA 4OZEA 2VESA 1YHCA 3PS3A 3P3GA 3NZKA 4U3BA 2GO3A 4LCFA 5DROA 5DRQA 3PS1A 2JT2A 5DRPA 3P3CA 4FW4A 4OKGA 4LCHA 2O3ZA 4IS9A 2IESA 4ISAA 4FW7A 4J3DA 2GO4A 4MQYA 2J65A 3P76A 3UHMA 1XXEA 2IERA 4FW3A 1P42A 3PS2A 3P3EA 4FW5A
chains in the Genus database with same CATH superfamily
3M85D 4FW6A 4IZKA 2JEBA 4JI4I 5EL9A 4IFDB 2NPFA 5LMNI 4DPWA 4RPFA 4FWDA 1OYPA 3J81C 2WP8A 4DV7I 2WNRB 4DR4E 4B3RI 5DRPA 1FNMA 4IS9A 4IFDC 3CDJA 2HHHI 1J5EE 2PO0B 2HHHE 3D4JA 4AQYI 4M1KA 2IOPA 4JYAI 1A6FA 5FWKA 1OYRA 2HKJA 4FW3A 4FWGA 3ZM7A 1P42A 1HNWE 4DV4E 2HK3A 4DU8A 1YH8A 5EKWA 1Y4SA 3JAMC 2GS8A 2UUAI 2LJPA 1YHCA 1N36E 1R6LA 2DEIA 2HFUA 3DD6A 5A2QC 2V34A 4JI1I 4YY3E 2VQEI 1EA6A 4UT4A 5LMUI 3M7ND 2UUBE 2DEJA 2E1RA 4DV5E 1Z5AA 1H74A 4J3DA 2NN6D 4LF7E 2UU9I 3PYGA 2O1UA 2J7KA 5C0XE 4B3RE 4DR4I 4P7AA 2BA0G 3U1YA 3ZZUA 5C0XB 4B3MI 2X7IA 4MU0A 2V8PA 1HR0I 3J81Q 1IBLE 4JI4E 4IFDD 4DXLA 2WW4A 2UXCI 1I94I 1FKAE 2PO1B 1FWKA 4YHHE 4DUYE 4Z7YA 2AE8A 3V5RA 4LFAI 4JI3E 3GCMA 4EMDA 3PYDA 4IZJB 1R6MA 2PO2B 1VI7A 4X62I 4P52A 4OO1C 1E3HA 4LCGA 2ZM6I 4LFCE 2PNLA 1N0VC 1HNXE 4LF8I 5IT9C 2PNZB 4OO1F 1Z0WA 3PYEA 4JI0E 4ED4A 5JEAF 4FW9A 1N32E 2VQFE 4DV0I 1ELOA 5BR8I 3HJCA 4DR3E 3H4LA 3Q1QA 4OO1A 4JV5I 1UEKA 1Y4UA 1UDSA 2C37B 1KIJA 4DV5I 2V2QA 4JI5I 2NN6B 1Y5YA 4URLA 5K36A 3ZZTA 3K85A 1Z0GA 2O1WA 4AM3A 2NN6E 3PYFA 4DV1E 1ZM3A 2UXCE 1XHKA 2PNZA 2VESA 1KVKA 4HACB 2IOQA 1RHYA 3K1JA 1IBLI 1IBMI 4DV3I 2BV3A 4XTJA 1PKPA 1XNRI 1H7UA 1QZRA 4PRXA 3B82A 4PRVA 1PVGA 4UTGA 4NXMI 3Q6NA 1XXEA 2JEAA 3KRNA 3P3EA 4BA2A 2C38B 2VQFI 4DR1E 5DNXA 3T1HI 2PO1A 5K36B 5JEAB 3V2UC 4JI6I 4OX9E 1Y60A 3L7ZA 2UUBI 1ZXMA 4BA1B 4DPXA 2JEAB 2UXBI 1HK7A 2JE6A 1H72C 5BR8E 3T1YE 5K36F 1HNZI 2BR2B 1ZM2A 3ZKDA 3PS2A 1XMOI 3Q6MA 1Z5CA 3B8HA 5C0XA 1XMOE 5JEAD 1FI4A 2WP8B 4JI5E 2O1VA 1IBKI 1I94E 4JI7I 5JEAA 1XMQI 4HYMA 1N33E 4DV4I 3LTOA 4LCHA 4DUYI 4B3TE 4LF6E 2EFGA 4KHPI 4LFAE 3OTOE 5C0XC 4NBQA 2F4VE 2BM1A 4LFCI 2CG9A 4AIMA 4IZJD 2BA1D 4ZVIA 1UDOA 1USUA 4X66E 2CGEA 4OZEA 3PS3A 4LF7I 4NXME 4HY1A 2CVEA 4LCFA 3CWVA 3H1CA 2VF3A 3K17A 1FJGE 4OKGA 4X64I 4LFBI 4IFDE 5FLXQ 2O3ZA 4DR6E 1VISA 4IZKB 1ZXNA 5JEAC 2Z5EA 5LMUE 3M6AA 2ZITA 1Z0TA 3ZZ0A 1KTVA 4DR7I 1Z5BA 4LF4E 4LFBE 1UDQA 4DR2I 5LL6R 1XNQE 4JI1E 4FW7A 1XMQE 2R3VA 4JV5E 1B62A 4WUCA 1H73A 1UDNA 1RREA 2BR2A 4U3DA 3OTOI 2Q2EB 3LNUA 4KQVA 4PU9A 1IBKE 2R42A 3P3GA 2PNMA 1XNRE 4U3BA 4NXNE 4FWHA 2PO2A 4AQYE 4USKA 3GMEA 4DV3E 3M85G 5C0XF 2V2ZA 5IWAE 4LF9E 3WU4A 5IWAI 4LF9I 2F4VI 4LF8E 3J7AM 2F1DA 4LF6I 1ZM4A 4JI0I 2NN6C 2HK2A 1J5EI 4YHHI 3WU5A 4R1FA 2NN6F 4JI6E 4OX9I 5DRRA 1E3PA 1Z0BA 3HULA 1HNZE 1N34I 1NHIA 1MU5A 2GO3A 3PRYA 2C39A 4DR2E 4B3SI 5FLXC 2XEXA 4JI2E 1BKNA 1NHJA 1RR9A 1U2RA 4MYTA 2BA1G 4X64E 3QT7A 1HNXI 4OO1B 2PO0A 1S16A 1IBME 4OO1E 4N3OA 4B3ME 4MDTA 5DNLA 1S4EA 4IFDA 3J7AG 4MU4A 2HFSA 4BA2B 4DV2I 4DV6E 2C39B 4WUDA 1XNQI 4X65I 4B3TI 4KHPE 4ISAA 2E5LI 4QNKA 2O1TA 3J80C 4GKKI 4GKJE 4B3SE 2BA0D 4LOMA 4K0KE 4AIDA 2WNRA 3QT5A 2ZM6E 4DPUA 1Z0VA 4USMA 1K47A 4GKJI 2UXBE 4JYAE 1OYSA 3PS1A 1KKHA 2HKEA 2Z5BA 4DR6I 4Z7CA 3T1HE 5K36C 4DV1I 4LF4I 4OO1D 4LPFA 2Z5CB 4NXNI 1Y6ZA 4JI8I 2GQ0A 5K36D 4WUBA 3ZKBA 5LMNE 4BA1A 2E5LE 4DV6I 3WU6A 4JI7E 3CDIA 2UU9E 1USVA 3B4TA 2JE6B 5IT9Q 1ZM9A 5DRQA 4FN5A 3P3CA 2Z5BB 4MYUA 3HKMA 4DV2E 4GQUA 3J80Q 4X65E 2GO4A 2IERA 4DPTA 4IFDF 1N0UA 1N36I 5ELWA 4JI2I 1OJ4A 3LPSA 3QT8A 4MU1A 3NZKA 4HACA 4YY3I 2VQEE 5GMEA 4FW4A 4DU7A 1PIEA 2JEBB 1N34E 1NHHA 5K36E 5JEAE 4DUZI 4DPYA 2ZBKB 2J65A 1MX0A 3F0NA 3P76A 1Z0CA 2AJ4A 3GONA 4I3HA 1WUUA 2A2CA 2A2DA 2UUCE 4LF5E 4MU3A 5DROA 1EI1A 2Z5CA 2X36A 3P06A 1N33I 1FWLA 2UUCI 4LF5I 4K0KI 1DARA 4IZJA 2UUAE 4MQYA 3UHMA 1NZ0A 4GKKE 3WU3A 3M7NG 4X62E 4HXZA 4DV7E 2UXDE 2C38A 5GMDA 1H7SA 4FW5A 1N32I 1HNWI 4JI3I 1FJGI 4DR1I 4DUZE 3JAMQ 3QT6A 5L3JA 4DR5E 3U1KA 1Z0EA 2UXDI 3T1YI 2BM0A 4JG4A 4DR7E 2JT2A 3GLLA 5A2QQ 4X66I 4DV0E 2V2VA 2OI2A 4DR5I 1MG7A 2IESA 1HR0E 1D6TA 3B78A 4JI8E 3L7ZB 2NN6A 4QNJA 1B63A 2C37A 5C0XD 2CZ9A 4DR3I 1Z59A
chains in the Genus database with same CATH topology
4MDTA 3U1YA 4FW6A 4LCGA 1YH8A 4U3DA 5DRRA 4OZEA 2VESA 1YHCA 3PS3A 3P3GA 3NZKA 4U3BA 2GO3A 4LCFA 5DROA 5DRQA 3PS1A 2JT2A 5DRPA 3P3CA 4FW4A 4OKGA 4LCHA 2O3ZA 4IS9A 2IESA 4ISAA 4FW7A 4J3DA 2GO4A 4MQYA 2J65A 3P76A 3UHMA 1XXEA 2IERA 4FW3A 1P42A 3PS2A 3P3EA 4FW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MDT A;  3U1Y A;  4FW6 A;  4LCG A;  1YH8 A;  4U3D A;  5DRR A;  4OZE A;  2VES A;  1YHC A;  3PS3 A;  3P3G A;  3NZK A;  4U3B A;  2GO3 A;  4LCF A;  5DRO A;  5DRQ A;  3PS1 A;  2JT2 A;  5DRP A;  3P3C A;  4FW4 A;  4OKG A;  4LCH A;  2O3Z A;  4IS9 A;  2IES A;  4ISA A;  4FW7 A;  4J3D A;  2GO4 A;  4MQY A;  2J65 A;  3P76 A;  3UHM A;  1XXE A;  2IER A;  4FW3 A;  1P42 A;  3PS2 A;  3P3E A;  4FW5 A; 
#chains in the Genus database with same CATH topology
 3M85 D;  4FW6 A;  4IZK A;  2JEB A;  4JI4 I;  5EL9 A;  4IFD B;  2NPF A;  5LMN I;  4DPW A;  4RPF A;  4FWD A;  1OYP A;  3J81 C;  2WP8 A;  4DV7 I;  2WNR B;  4DR4 E;  4B3R I;  5DRP A;  1FNM A;  4IS9 A;  4IFD C;  3CDJ A;  2HHH I;  1J5E E;  2PO0 B;  2HHH E;  3D4J A;  4AQY I;  4M1K A;  2IOP A;  4JYA I;  1A6F A;  5FWK A;  1OYR A;  2HKJ A;  4FW3 A;  4FWG A;  3ZM7 A;  1P42 A;  1HNW E;  4DV4 E;  2HK3 A;  4DU8 A;  1YH8 A;  5EKW A;  1Y4S A;  3JAM C;  2GS8 A;  2UUA I;  2LJP A;  1YHC A;  1N36 E;  1R6L A;  2DEI A;  2HFU A;  3DD6 A;  5A2Q C;  2V34 A;  4JI1 I;  4YY3 E;  2VQE I;  1EA6 A;  4UT4 A;  5LMU I;  3M7N D;  2UUB E;  2DEJ A;  2E1R A;  4DV5 E;  1Z5A A;  1H74 A;  4J3D A;  2NN6 D;  4LF7 E;  2UU9 I;  3PYG A;  2O1U A;  2J7K A;  5C0X E;  4B3R E;  4DR4 I;  4P7A A;  2BA0 G;  3U1Y A;  3ZZU A;  5C0X B;  4B3M I;  2X7I A;  4MU0 A;  2V8P A;  1HR0 I;  3J81 Q;  1IBL E;  4JI4 E;  4IFD D;  4DXL A;  2WW4 A;  2UXC I;  1I94 I;  1FKA E;  2PO1 B;  1FWK A;  4YHH E;  4DUY E;  4Z7Y A;  2AE8 A;  3V5R A;  4LFA I;  4JI3 E;  3GCM A;  4EMD A;  3PYD A;  4IZJ B;  1R6M A;  2PO2 B;  1VI7 A;  4X62 I;  4P52 A;  4OO1 C;  1E3H A;  4LCG A;  2ZM6 I;  4LFC E;  2PNL A;  1N0V C;  1HNX E;  4LF8 I;  5IT9 C;  2PNZ B;  4OO1 F;  1Z0W A;  3PYE A;  4JI0 E;  4ED4 A;  5JEA F;  4FW9 A;  1N32 E;  2VQF E;  4DV0 I;  1ELO A;  5BR8 I;  3HJC A;  4DR3 E;  3H4L A;  3Q1Q A;  4OO1 A;  4JV5 I;  1UEK A;  1Y4U A;  1UDS A;  2C37 B;  1KIJ A;  4DV5 I;  2V2Q A;  4JI5 I;  2NN6 B;  1Y5Y A;  4URL A;  5K36 A;  3ZZT A;  3K85 A;  1Z0G A;  2O1W A;  4AM3 A;  2NN6 E;  3PYF A;  4DV1 E;  1ZM3 A;  2UXC E;  1XHK A;  2PNZ A;  2VES A;  1KVK A;  4HAC B;  2IOQ A;  1RHY A;  3K1J A;  1IBL I;  1IBM I;  4DV3 I;  2BV3 A;  4XTJ A;  1PKP A;  1XNR I;  1H7U A;  1QZR A;  4PRX A;  3B82 A;  4PRV A;  1PVG A;  4UTG A;  4NXM I;  3Q6N A;  1XXE A;  2JEA A;  3KRN A;  3P3E A;  4BA2 A;  2C38 B;  2VQF I;  4DR1 E;  5DNX A;  3T1H I;  2PO1 A;  5K36 B;  5JEA B;  3V2U C;  4JI6 I;  4OX9 E;  1Y60 A;  3L7Z A;  2UUB I;  1ZXM A;  4BA1 B;  4DPX A;  2JEA B;  2UXB I;  1HK7 A;  2JE6 A;  1H72 C;  5BR8 E;  3T1Y E;  5K36 F;  1HNZ I;  2BR2 B;  1ZM2 A;  3ZKD A;  3PS2 A;  1XMO I;  3Q6M A;  1Z5C A;  3B8H A;  5C0X A;  1XMO E;  5JEA D;  1FI4 A;  2WP8 B;  4JI5 E;  2O1V A;  1IBK I;  1I94 E;  4JI7 I;  5JEA A;  1XMQ I;  4HYM A;  1N33 E;  4DV4 I;  3LTO A;  4LCH A;  4DUY I;  4B3T E;  4LF6 E;  2EFG A;  4KHP I;  4LFA E;  3OTO E;  5C0X C;  4NBQ A;  2F4V E;  2BM1 A;  4LFC I;  2CG9 A;  4AIM A;  4IZJ D;  2BA1 D;  4ZVI A;  1UDO A;  1USU A;  4X66 E;  2CGE A;  4OZE A;  3PS3 A;  4LF7 I;  4NXM E;  4HY1 A;  2CVE A;  4LCF A;  3CWV A;  3H1C A;  2VF3 A;  3K17 A;  1FJG E;  4OKG A;  4X64 I;  4LFB I;  4IFD E;  5FLX Q;  2O3Z A;  4DR6 E;  1VIS A;  4IZK B;  1ZXN A;  5JEA C;  2Z5E A;  5LMU E;  3M6A A;  2ZIT A;  1Z0T A;  3ZZ0 A;  1KTV A;  4DR7 I;  1Z5B A;  4LF4 E;  4LFB E;  1UDQ A;  4DR2 I;  5LL6 R;  1XNQ E;  4JI1 E;  4FW7 A;  1XMQ E;  2R3V A;  4JV5 E;  1B62 A;  4WUC A;  1H73 A;  1UDN A;  1RRE A;  2BR2 A;  4U3D A;  3OTO I;  2Q2E B;  3LNU A;  4KQV A;  4PU9 A;  1IBK E;  2R42 A;  3P3G A;  2PNM A;  1XNR E;  4U3B A;  4NXN E;  4FWH A;  2PO2 A;  4AQY E;  4USK A;  3GME A;  4DV3 E;  3M85 G;  5C0X F;  2V2Z A;  5IWA E;  4LF9 E;  3WU4 A;  5IWA I;  4LF9 I;  2F4V I;  4LF8 E;  3J7A M;  2F1D A;  4LF6 I;  1ZM4 A;  4JI0 I;  2NN6 C;  2HK2 A;  1J5E I;  4YHH I;  3WU5 A;  4R1F A;  2NN6 F;  4JI6 E;  4OX9 I;  5DRR A;  1E3P A;  1Z0B A;  3HUL A;  1HNZ E;  1N34 I;  1NHI A;  1MU5 A;  2GO3 A;  3PRY A;  2C39 A;  4DR2 E;  4B3S I;  5FLX C;  2XEX A;  4JI2 E;  1BKN A;  1NHJ A;  1RR9 A;  1U2R A;  4MYT A;  2BA1 G;  4X64 E;  3QT7 A;  1HNX I;  4OO1 B;  2PO0 A;  1S16 A;  1IBM E;  4OO1 E;  4N3O A;  4B3M E;  4MDT A;  5DNL A;  1S4E A;  4IFD A;  3J7A G;  4MU4 A;  2HFS A;  4BA2 B;  4DV2 I;  4DV6 E;  2C39 B;  4WUD A;  1XNQ I;  4X65 I;  4B3T I;  4KHP E;  4ISA A;  2E5L I;  4QNK A;  2O1T A;  3J80 C;  4GKK I;  4GKJ E;  4B3S E;  2BA0 D;  4LOM A;  4K0K E;  4AID A;  2WNR A;  3QT5 A;  2ZM6 E;  4DPU A;  1Z0V A;  4USM A;  1K47 A;  4GKJ I;  2UXB E;  4JYA E;  1OYS A;  3PS1 A;  1KKH A;  2HKE A;  2Z5B A;  4DR6 I;  4Z7C A;  3T1H E;  5K36 C;  4DV1 I;  4LF4 I;  4OO1 D;  4LPF A;  2Z5C B;  4NXN I;  1Y6Z A;  4JI8 I;  2GQ0 A;  5K36 D;  4WUB A;  3ZKB A;  5LMN E;  4BA1 A;  2E5L E;  4DV6 I;  3WU6 A;  4JI7 E;  3CDI A;  2UU9 E;  1USV A;  3B4T A;  2JE6 B;  5IT9 Q;  1ZM9 A;  5DRQ A;  4FN5 A;  3P3C A;  2Z5B B;  4MYU A;  3HKM A;  4DV2 E;  4GQU A;  3J80 Q;  4X65 E;  2GO4 A;  2IER A;  4DPT A;  4IFD F;  1N0U A;  1N36 I;  5ELW A;  4JI2 I;  1OJ4 A;  3LPS A;  3QT8 A;  4MU1 A;  3NZK A;  4HAC A;  4YY3 I;  2VQE E;  5GME A;  4FW4 A;  4DU7 A;  1PIE A;  2JEB B;  1N34 E;  1NHH A;  5K36 E;  5JEA E;  4DUZ I;  4DPY A;  2ZBK B;  2J65 A;  1MX0 A;  3F0N A;  3P76 A;  1Z0C A;  2AJ4 A;  3GON A;  4I3H A;  1WUU A;  2A2C A;  2A2D A;  2UUC E;  4LF5 E;  4MU3 A;  5DRO A;  1EI1 A;  2Z5C A;  2X36 A;  3P06 A;  1N33 I;  1FWL A;  2UUC I;  4LF5 I;  4K0K I;  1DAR A;  4IZJ A;  2UUA E;  4MQY A;  3UHM A;  1NZ0 A;  4GKK E;  3WU3 A;  3M7N G;  4X62 E;  4HXZ A;  4DV7 E;  2UXD E;  2C38 A;  5GMD A;  1H7S A;  4FW5 A;  1N32 I;  1HNW I;  4JI3 I;  1FJG I;  4DR1 I;  4DUZ E;  3JAM Q;  3QT6 A;  5L3J A;  4DR5 E;  3U1K A;  1Z0E A;  2UXD I;  3T1Y I;  2BM0 A;  4JG4 A;  4DR7 E;  2JT2 A;  3GLL A;  5A2Q Q;  4X66 I;  4DV0 E;  2V2V A;  2OI2 A;  4DR5 I;  1MG7 A;  2IES A;  1HR0 E;  1D6T A;  3B78 A;  4JI8 E;  3L7Z B;  2NN6 A;  4QNJ A;  1B63 A;  2C37 A;  5C0X D;  2CZ9 A;  4DR3 I;  1Z59 A; 
#chains in the Genus database with same CATH homology
 4MDT A;  3U1Y A;  4FW6 A;  4LCG A;  1YH8 A;  4U3D A;  5DRR A;  4OZE A;  2VES A;  1YHC A;  3PS3 A;  3P3G A;  3NZK A;  4U3B A;  2GO3 A;  4LCF A;  5DRO A;  5DRQ A;  3PS1 A;  2JT2 A;  5DRP A;  3P3C A;  4FW4 A;  4OKG A;  4LCH A;  2O3Z A;  4IS9 A;  2IES A;  4ISA A;  4FW7 A;  4J3D A;  2GO4 A;  4MQY A;  2J65 A;  3P76 A;  3UHM A;  1XXE A;  2IER A;  4FW3 A;  1P42 A;  3PS2 A;  3P3E A;  4FW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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