4J7GA

Crystal structure of evaa, a 2,3-dehydratase in complex with dtdp-fucose and dtdp-rhamnose
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
458
structure length
448
Chain Sequence
AVRPRDHHDYADRIALSAATTDGVQMRTEDVRAWIAERRDANVFHVERIPFADLDQWWFEGVTGNLVHRSGRFFTIEGLHVIEHDGPHGDGPYREWQQPVIRQPEVGILGILAKEFDGVLHFLMQAKMEPGNPNLVQLSPTVQATRSNYTNVKLIEYFAPPDPERVIVDVLQAEQGSWFFRKSNRNMIVETVDDVPLWDDFCWLTLGQIAELMHEDETINMNSRSVLSCLPYQDITPRALFSDVQLLSWFTNERSRHDVRVRRIPLADVCGWKQGAEEIEHEDGRYFKVLAVAVKGSISWTQPLVESVDLGVVAFLVRKIDGVPHVLVQARVDGGFLDTVELAPTVQCTPLNYAHLPAEEAPPFLDLVQNAPRSRIRYEAIHSEEGGRFLGVRARYLVIDADEAIDPPPGYAWVTPAQLTALTRHGHYVNVEARTLLACINAAAAQPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords EvaA 2,3-dehydratase
publication title Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
pubmed doi rcsb
source organism Amycolatopsis orientalis
molecule tags Biosynthetic protein
total genus 135
structure length 448
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.2.1.159: dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase.
pdb deposition date 2013-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03559 Hexose_dehydrat NDP-hexose 2,3-dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.79.40 Alpha Beta Alpha-Beta Complex Nucleoside Triphosphate Pyrophosphohydrolase Nucleoside Triphosphate Pyrophosphohydrolase 4j7gA02
4J7HA 4J7GA
chains in the Genus database with same CATH superfamily
1KHZA 3ACAA 5HZXA 3A6VA 5BS6A 5FSMA 3DUPA 3FJYA 3A6TA 2DSBA 3Q93A 3EEUA 4KYXA 1V8UA 3Q2SA 1QVJA 3X0RA 2DUKA 4NFWA 4DYWA 3FFUA 2CZRA 2A8TA 1PUQA 1VC9A 2Q9PA 3BHOA 1MUTA 2A6TA 1V8YA 3O8SA 1JRKA 3KVHA 3P5TA 3E57A 3X0QA 1KTGA 2QJTA 1MQEA 1VC8A 3FCMA 1SU2A 3N77A 3QSJA 4IJXA 4J7HA 1VRLA 3GZ8A 3GZ6A 4YPRA 1PVFA 1GA7A 2O5FA 5IW5A 3FSPA 4N1TA 5DD4A 1X84A 1V8TA 3SMDA 3OGAA 1SJYA 2FVVA 1X83A 2RRKA 2YVNA 2GB5A 3Q4IA 3ZR0A 1HX3A 3O6ZA 2YVMA 3MGMA 5IW4A 3G0QA 1MK1A 4YOQA 3Q1PA 5ANUA 1V8IA 3F6AA 3F13A 3X0IA 1I9AA 2QKMB 1XSAA 1PPWA 3FK9A 2VNQA 3O69A 3X0JA 1MR2A 1NQZA 3X0MA 1G0SA 2B0VA 2KDWA 2KDVA 3ID9A 1RRQA 4ZG0A 1MQWA 2PNYA 1XSBA 1XSCA 5GHJA 5C8LA 1F3YA 3MCFA 4KG4A 5ANTA 5ANSA 4ICKA 5GHPA 2GT4A 2A8SA 1JKNA 1NFSA 3X0KA 3Q2TA 5GHIA 3GG6A 3P6YA 1SZ3A 1Q27A 2A8PA 3I9XA 5FSNA 2O5WA 3RH7A 1MP2A 1U20A 3ZR1A 3J7Ye 3WHWA 3AC9A 1PUNA 4ILQA 4S2WA 3N9UA 2I6KA 2XSQA 2A8RA 5FSOA 1KT9A 2DHOA 3X0LA 4V14A 5DPKA 3EF5A 2I8UA 2DSCA 5FSIA 1RRSA 1G9QA 5GHMA 1V8RA 1R67A 4K6EA 3X0NA 3U53A 1Q54A 1Q33A 2O1CA 3CNGA 3GWYA 2AZWA 4JZVA 4JZUA 1VCDA 1V8MA 4JZSA 2ICKA 5LPGA 3Q91A 4C9XA 3A6SA 5CFJA 1VHGA 2FMLA 2J8QA 2CL3A 5BONA 2W4EA 1VHZA 2ICJA 3X0OA 5FSLA 4YPHA 3SONA 4N1UA 5I8UA 1HZTA 4JZTA 4C9WA 5GHQA 3GRNA 5ANWA 3H95A 1RYAA 2DSDA 4NFXA 5C7TA 4S2XA 2B06A 1V8LA 4S2VA 2I8TA 3O61A 5ANVA 4KG3A 1VIQA 1V8SA 3I7UA 3A6UA 5CFIA 2JVBA 1PPVA 3X0SA 3L85A 4HFQA 1V8WA 1VIUA 1OW2A 2FKBA 4J7GA 3O52A 2QJOA 5FSKA 5GHOA 2YVOA 1VK6A 1X51A 2YYHA 1SOIA 2B2KA 1PPXA 3GZ5A 3I7VA 3MDGA 5ISYA 1V8VA 2G73A 2G74A 3MDIA 3DKUA 4MPOA 1TUMA 3EXQA 3BM4A 3HHJA 5GHNA 4KTBA 4HVYA 1NQYA 2GT2A 2R5WA 3COUA 3HYQA 2YVPA 1IRYA 3BAPA 4S2YA 2VNPA 1K2EA 2PQVA 1K26A 5DEQA 2A8QA 1V8NA 1PUSA 3R03A 5DDGA 3X0PA 5C7QA 3SHDA 1NFZA 3EESA
chains in the Genus database with same CATH topology
1KHZA 3ACAA 5HZXA 3A6VA 5BS6A 5FSMA 3DUPA 3FJYA 3A6TA 2DSBA 3Q93A 3EEUA 4KYXA 1V8UA 3Q2SA 1QVJA 3X0RA 2DUKA 4NFWA 4DYWA 3FFUA 2CZRA 2A8TA 1PUQA 1VC9A 2Q9PA 3BHOA 1MUTA 2A6TA 1V8YA 3O8SA 1JRKA 3KVHA 3P5TA 3E57A 3X0QA 1KTGA 2QJTA 1MQEA 1VC8A 3FCMA 1SU2A 3N77A 3QSJA 4IJXA 4J7HA 1VRLA 3GZ8A 3GZ6A 4YPRA 1PVFA 1GA7A 2O5FA 5IW5A 3FSPA 4N1TA 5DD4A 1X84A 1V8TA 3SMDA 3OGAA 1SJYA 2FVVA 1X83A 2RRKA 2YVNA 2GB5A 3Q4IA 3ZR0A 1HX3A 3O6ZA 2YVMA 3MGMA 5IW4A 3G0QA 1MK1A 4YOQA 3Q1PA 5ANUA 1V8IA 3F6AA 3F13A 3X0IA 1I9AA 2QKMB 1XSAA 1PPWA 3FK9A 2VNQA 3O69A 3X0JA 1MR2A 1NQZA 3X0MA 1G0SA 2B0VA 2KDWA 2KDVA 3ID9A 1RRQA 4ZG0A 1MQWA 2PNYA 1XSBA 1XSCA 5GHJA 5C8LA 1F3YA 3MCFA 4KG4A 5ANTA 5ANSA 4ICKA 5GHPA 2GT4A 2A8SA 1JKNA 1NFSA 3X0KA 3Q2TA 5GHIA 3GG6A 3P6YA 1SZ3A 1Q27A 2A8PA 3I9XA 5FSNA 2O5WA 3RH7A 1MP2A 1U20A 3ZR1A 3J7Ye 3WHWA 3AC9A 1PUNA 4ILQA 4S2WA 3N9UA 2I6KA 2XSQA 2A8RA 5FSOA 1KT9A 2DHOA 3X0LA 4V14A 5DPKA 3EF5A 2I8UA 2DSCA 5FSIA 1RRSA 1G9QA 5GHMA 1V8RA 1R67A 4K6EA 3X0NA 3U53A 1Q54A 1Q33A 2O1CA 3CNGA 3GWYA 2AZWA 4JZVA 4JZUA 1VCDA 1V8MA 4JZSA 2ICKA 5LPGA 3Q91A 4C9XA 3A6SA 5CFJA 1VHGA 2FMLA 2J8QA 2CL3A 5BONA 2W4EA 1VHZA 2ICJA 3X0OA 5FSLA 4YPHA 3SONA 4N1UA 5I8UA 1HZTA 4JZTA 4C9WA 5GHQA 3GRNA 5ANWA 3H95A 1RYAA 2DSDA 4NFXA 5C7TA 4S2XA 2B06A 1V8LA 4S2VA 2I8TA 3O61A 5ANVA 4KG3A 1VIQA 1V8SA 3I7UA 3A6UA 5CFIA 2JVBA 1PPVA 3X0SA 3L85A 4HFQA 1V8WA 1VIUA 1OW2A 2FKBA 4J7GA 3O52A 2QJOA 5FSKA 5GHOA 2YVOA 1VK6A 1X51A 2YYHA 1SOIA 2B2KA 1PPXA 3GZ5A 3I7VA 3MDGA 5ISYA 1V8VA 2G73A 2G74A 3MDIA 3DKUA 4MPOA 1TUMA 3EXQA 3BM4A 3HHJA 5GHNA 4KTBA 4HVYA 1NQYA 2GT2A 2R5WA 3COUA 3HYQA 2YVPA 1IRYA 3BAPA 4S2YA 2VNPA 1K2EA 2PQVA 1K26A 5DEQA 2A8QA 1V8NA 1PUSA 3R03A 5DDGA 3X0PA 5C7QA 3SHDA 1NFZA 3EESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J7H A;  4J7G A; 
#chains in the Genus database with same CATH topology
 1KHZ A;  3ACA A;  5HZX A;  3A6V A;  5BS6 A;  5FSM A;  3DUP A;  3FJY A;  3A6T A;  2DSB A;  3Q93 A;  3EEU A;  4KYX A;  1V8U A;  3Q2S A;  1QVJ A;  3X0R A;  2DUK A;  4NFW A;  4DYW A;  3FFU A;  2CZR A;  2A8T A;  1PUQ A;  1VC9 A;  2Q9P A;  3BHO A;  1MUT A;  2A6T A;  1V8Y A;  3O8S A;  1JRK A;  3KVH A;  3P5T A;  3E57 A;  3X0Q A;  1KTG A;  2QJT A;  1MQE A;  1VC8 A;  3FCM A;  1SU2 A;  3N77 A;  3QSJ A;  4IJX A;  4J7H A;  1VRL A;  3GZ8 A;  3GZ6 A;  4YPR A;  1PVF A;  1GA7 A;  2O5F A;  5IW5 A;  3FSP A;  4N1T A;  5DD4 A;  1X84 A;  1V8T A;  3SMD A;  3OGA A;  1SJY A;  2FVV A;  1X83 A;  2RRK A;  2YVN A;  2GB5 A;  3Q4I A;  3ZR0 A;  1HX3 A;  3O6Z A;  2YVM A;  3MGM A;  5IW4 A;  3G0Q A;  1MK1 A;  4YOQ A;  3Q1P A;  5ANU A;  1V8I A;  3F6A A;  3F13 A;  3X0I A;  1I9A A;  2QKM B;  1XSA A;  1PPW A;  3FK9 A;  2VNQ A;  3O69 A;  3X0J A;  1MR2 A;  1NQZ A;  3X0M A;  1G0S A;  2B0V A;  2KDW A;  2KDV A;  3ID9 A;  1RRQ A;  4ZG0 A;  1MQW A;  2PNY A;  1XSB A;  1XSC A;  5GHJ A;  5C8L A;  1F3Y A;  3MCF A;  4KG4 A;  5ANT A;  5ANS A;  4ICK A;  5GHP A;  2GT4 A;  2A8S A;  1JKN A;  1NFS A;  3X0K A;  3Q2T A;  5GHI A;  3GG6 A;  3P6Y A;  1SZ3 A;  1Q27 A;  2A8P A;  3I9X A;  5FSN A;  2O5W A;  3RH7 A;  1MP2 A;  1U20 A;  3ZR1 A;  3J7Y e;  3WHW A;  3AC9 A;  1PUN A;  4ILQ A;  4S2W A;  3N9U A;  2I6K A;  2XSQ A;  2A8R A;  5FSO A;  1KT9 A;  2DHO A;  3X0L A;  4V14 A;  5DPK A;  3EF5 A;  2I8U A;  2DSC A;  5FSI A;  1RRS A;  1G9Q A;  5GHM A;  1V8R A;  1R67 A;  4K6E A;  3X0N A;  3U53 A;  1Q54 A;  1Q33 A;  2O1C A;  3CNG A;  3GWY A;  2AZW A;  4JZV A;  4JZU A;  1VCD A;  1V8M A;  4JZS A;  2ICK A;  5LPG A;  3Q91 A;  4C9X A;  3A6S A;  5CFJ A;  1VHG A;  2FML A;  2J8Q A;  2CL3 A;  5BON A;  2W4E A;  1VHZ A;  2ICJ A;  3X0O A;  5FSL A;  4YPH A;  3SON A;  4N1U A;  5I8U A;  1HZT A;  4JZT A;  4C9W A;  5GHQ A;  3GRN A;  5ANW A;  3H95 A;  1RYA A;  2DSD A;  4NFX A;  5C7T A;  4S2X A;  2B06 A;  1V8L A;  4S2V A;  2I8T A;  3O61 A;  5ANV A;  4KG3 A;  1VIQ A;  1V8S A;  3I7U A;  3A6U A;  5CFI A;  2JVB A;  1PPV A;  3X0S A;  3L85 A;  4HFQ A;  1V8W A;  1VIU A;  1OW2 A;  2FKB A;  4J7G A;  3O52 A;  2QJO A;  5FSK A;  5GHO A;  2YVO A;  1VK6 A;  1X51 A;  2YYH A;  1SOI A;  2B2K A;  1PPX A;  3GZ5 A;  3I7V A;  3MDG A;  5ISY A;  1V8V A;  2G73 A;  2G74 A;  3MDI A;  3DKU A;  4MPO A;  1TUM A;  3EXQ A;  3BM4 A;  3HHJ A;  5GHN A;  4KTB A;  4HVY A;  1NQY A;  2GT2 A;  2R5W A;  3COU A;  3HYQ A;  2YVP A;  1IRY A;  3BAP A;  4S2Y A;  2VNP A;  1K2E A;  2PQV A;  1K26 A;  5DEQ A;  2A8Q A;  1V8N A;  1PUS A;  3R03 A;  5DDG A;  3X0P A;  5C7Q A;  3SHD A;  1NFZ A;  3EES A; 
#chains in the Genus database with same CATH homology
 1KHZ A;  3ACA A;  5HZX A;  3A6V A;  5BS6 A;  5FSM A;  3DUP A;  3FJY A;  3A6T A;  2DSB A;  3Q93 A;  3EEU A;  4KYX A;  1V8U A;  3Q2S A;  1QVJ A;  3X0R A;  2DUK A;  4NFW A;  4DYW A;  3FFU A;  2CZR A;  2A8T A;  1PUQ A;  1VC9 A;  2Q9P A;  3BHO A;  1MUT A;  2A6T A;  1V8Y A;  3O8S A;  1JRK A;  3KVH A;  3P5T A;  3E57 A;  3X0Q A;  1KTG A;  2QJT A;  1MQE A;  1VC8 A;  3FCM A;  1SU2 A;  3N77 A;  3QSJ A;  4IJX A;  4J7H A;  1VRL A;  3GZ8 A;  3GZ6 A;  4YPR A;  1PVF A;  1GA7 A;  2O5F A;  5IW5 A;  3FSP A;  4N1T A;  5DD4 A;  1X84 A;  1V8T A;  3SMD A;  3OGA A;  1SJY A;  2FVV A;  1X83 A;  2RRK A;  2YVN A;  2GB5 A;  3Q4I A;  3ZR0 A;  1HX3 A;  3O6Z A;  2YVM A;  3MGM A;  5IW4 A;  3G0Q A;  1MK1 A;  4YOQ A;  3Q1P A;  5ANU A;  1V8I A;  3F6A A;  3F13 A;  3X0I A;  1I9A A;  2QKM B;  1XSA A;  1PPW A;  3FK9 A;  2VNQ A;  3O69 A;  3X0J A;  1MR2 A;  1NQZ A;  3X0M A;  1G0S A;  2B0V A;  2KDW A;  2KDV A;  3ID9 A;  1RRQ A;  4ZG0 A;  1MQW A;  2PNY A;  1XSB A;  1XSC A;  5GHJ A;  5C8L A;  1F3Y A;  3MCF A;  4KG4 A;  5ANT A;  5ANS A;  4ICK A;  5GHP A;  2GT4 A;  2A8S A;  1JKN A;  1NFS A;  3X0K A;  3Q2T A;  5GHI A;  3GG6 A;  3P6Y A;  1SZ3 A;  1Q27 A;  2A8P A;  3I9X A;  5FSN A;  2O5W A;  3RH7 A;  1MP2 A;  1U20 A;  3ZR1 A;  3J7Y e;  3WHW A;  3AC9 A;  1PUN A;  4ILQ A;  4S2W A;  3N9U A;  2I6K A;  2XSQ A;  2A8R A;  5FSO A;  1KT9 A;  2DHO A;  3X0L A;  4V14 A;  5DPK A;  3EF5 A;  2I8U A;  2DSC A;  5FSI A;  1RRS A;  1G9Q A;  5GHM A;  1V8R A;  1R67 A;  4K6E A;  3X0N A;  3U53 A;  1Q54 A;  1Q33 A;  2O1C A;  3CNG A;  3GWY A;  2AZW A;  4JZV A;  4JZU A;  1VCD A;  1V8M A;  4JZS A;  2ICK A;  5LPG A;  3Q91 A;  4C9X A;  3A6S A;  5CFJ A;  1VHG A;  2FML A;  2J8Q A;  2CL3 A;  5BON A;  2W4E A;  1VHZ A;  2ICJ A;  3X0O A;  5FSL A;  4YPH A;  3SON A;  4N1U A;  5I8U A;  1HZT A;  4JZT A;  4C9W A;  5GHQ A;  3GRN A;  5ANW A;  3H95 A;  1RYA A;  2DSD A;  4NFX A;  5C7T A;  4S2X A;  2B06 A;  1V8L A;  4S2V A;  2I8T A;  3O61 A;  5ANV A;  4KG3 A;  1VIQ A;  1V8S A;  3I7U A;  3A6U A;  5CFI A;  2JVB A;  1PPV A;  3X0S A;  3L85 A;  4HFQ A;  1V8W A;  1VIU A;  1OW2 A;  2FKB A;  4J7G A;  3O52 A;  2QJO A;  5FSK A;  5GHO A;  2YVO A;  1VK6 A;  1X51 A;  2YYH A;  1SOI A;  2B2K A;  1PPX A;  3GZ5 A;  3I7V A;  3MDG A;  5ISY A;  1V8V A;  2G73 A;  2G74 A;  3MDI A;  3DKU A;  4MPO A;  1TUM A;  3EXQ A;  3BM4 A;  3HHJ A;  5GHN A;  4KTB A;  4HVY A;  1NQY A;  2GT2 A;  2R5W A;  3COU A;  3HYQ A;  2YVP A;  1IRY A;  3BAP A;  4S2Y A;  2VNP A;  1K2E A;  2PQV A;  1K26 A;  5DEQ A;  2A8Q A;  1V8N A;  1PUS A;  3R03 A;  5DDG A;  3X0P A;  5C7Q A;  3SHD A;  1NFZ A;  3EES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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