4J7GA

Crystal structure of evaa, a 2,3-dehydratase in complex with dtdp-fucose and dtdp-rhamnose
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
458
structure length
448
Chain Sequence
b'AVRPRDHHDYADRIALSAATTDGVQMRTEDVRAWIAERRDANVFHVERIPFADLDQWWFEGVTGNLVHRSGRFFTIEGLHVIEHDGPHGDGPYREWQQPVIRQPEVGILGILAKEFDGVLHFLMQAKMEPGNPNLVQLSPTVQATRSNYTNVKLIEYFAPPDPERVIVDVLQAEQGSWFFRKSNRNMIVETVDDVPLWDDFCWLTLGQIAELMHEDETINMNSRSVLSCLPYQDITPRALFSDVQLLSWFTNERSRHDVRVRRIPLADVCGWKQGAEEIEHEDGRYFKVLAVAVKGSISWTQPLVESVDLGVVAFLVRKIDGVPHVLVQARVDGGFLDTVELAPTVQCTPLNYAHLPAEEAPPFLDLVQNAPRSRIRYEAIHSEEGGRFLGVRARYLVIDADEAIDPPPGYAWVTPAQLTALTRHGHYVNVEARTLLACINAAAAQPR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords EvaA 2,3-dehydratase
publication title Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
pubmed doi rcsb
source organism Amycolatopsis orientalis
molecule tags Biosynthetic protein
total genus 135
structure length 448
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.2.1.159: dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase.
pdb deposition date 2013-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03559 Hexose_dehydrat NDP-hexose 2,3-dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.79.40 Alpha Beta Alpha-Beta Complex Nucleoside Triphosphate Pyrophosphohydrolase Nucleoside Triphosphate Pyrophosphohydrolase 4j7gA02
4J7HA 4J7GA
chains in the Genus database with same CATH superfamily
3FK9A 2O5FA 3X0RA 3ZR1A 2XSQA 1V8NA 2I8UA 4J7GA 1MP2A 2A8TA 1G0SA 3BAPA 4JZVA 1I9AA 1K26A 3O61A 3R03A 1PPVA 5DD4A 3X0KA 1PUSA 2FKBA 3Q93A 1JRKA 2ICKA 3COUA 3O8SA 5FSLA 5IW4A 5LPGA 2A8RA 5ISYA 2G74A 5CFJA 1VRLA 3I7UA 1HX3A 3X0SA 4J7HA 1VC9A 3Q91A 2B0VA 3BM4A 2GB5A 3OGAA 5GHMA 1V8SA 5GHIA 2QJOA 5FSNA 2W4EA 4N1TA 4HVYA 3MDGA 1Q27A 3GG6A 4MPOA 3Q2TA 1V8TA 5ANWA 1V8IA 1HZTA 1PUQA 1PVFA 1KHZA 1X84A 2VNPA 3FJYA 2YVPA 3E57A 2QKMB 1VIUA 3FSPA 1K2EA 1NQZA 1RRQA 3QSJA 1VCDA 1MQEA 2JVBA 2AZWA 3I9XA 2VNQA 3ID9A 2YVNA 5DEQA 3EEUA 1GA7A 3SMDA 2B2KA 5FSOA 1JKNA 1V8RA 3GZ5A 4DYWA 4HFQA 3HHJA 1V8UA 2A8QA 3BHOA 2ICJA 1U20A 5ANSA 5C8LA 5BONA 2DSDA 4S2WA 4YPHA 3L85A 3Q4IA 2G73A 2GT2A 3EESA 3O6ZA 5C7QA 5CFIA 4KTBA 1Q33A 5FSIA 4JZUA 3X0QA 2PQVA 5ANTA 3O52A 3Q2SA 4KYXA 3X0NA 1VC8A 4YOQA 2Q9PA 3Q1PA 1X51A 4JZSA 1X83A 2I6KA 2KDVA 5BS6A 3DUPA 4ILQA 4V14A 1V8VA 4ZG0A 3ACAA 1F3YA 5GHJA 2O5WA 1KT9A 3N9UA 1KTGA 4IJXA 1SZ3A 1OW2A 5GHOA 5GHPA 3KVHA 3GZ6A 2CZRA 2DSBA 1XSCA 3GZ8A 3F6AA 4C9XA 5GHQA 4S2XA 3GRNA 2GT4A 3O69A 4YPRA 1PPWA 1XSAA 1G9QA 4S2VA 2YVOA 1RRSA 5ANUA 1PPXA 2I8TA 1MQWA 4NFWA 2A8SA 4NFXA 5GHNA 3U53A 3ZR0A 2J8QA 3N77A 1XSBA 3H95A 5I8UA 1RYAA 1V8LA 4JZTA 2FMLA 2O1CA 3X0PA 1Q54A 3X0IA 1V8WA 5DDGA 2DHOA 5C7TA 3HYQA 1MK1A 4ICKA 3SONA 4C9WA 3AC9A 2CL3A 2A6TA 2YVMA 1V8MA 2YYHA 1MUTA 1NQYA 1NFZA 1VHGA 2A8PA 3EXQA 5FSKA 5FSMA 4S2YA 3GWYA 3A6UA 3DKUA 3X0LA 1V8YA 3MGMA 5IW5A 3A6VA 2FVVA 3MCFA 2DSCA 2PNYA 3FCMA 5ANVA 1MR2A 1VIQA 3CNGA 3WHWA 3X0OA 3X0JA 1IRYA 1QVJA 1SU2A 3P5TA 1VHZA 4KG4A 2RRKA 3X0MA 3J7Ye 4K6EA 3FFUA 3A6TA 2QJTA 5DPKA 3RH7A 3I7VA 1VK6A 1NFSA 2KDWA 1PUNA 3P6YA 4N1UA 3SHDA 1R67A 2B06A 1TUMA 2DUKA 1SOIA 4KG3A 5HZXA 3MDIA 3G0QA 3A6SA 2R5WA 1SJYA 3EF5A 3F13A
chains in the Genus database with same CATH topology
3FK9A 2O5FA 3X0RA 3ZR1A 2XSQA 1V8NA 2I8UA 4J7GA 1MP2A 2A8TA 1G0SA 3BAPA 4JZVA 1I9AA 1K26A 3O61A 3R03A 1PPVA 5DD4A 3X0KA 1PUSA 2FKBA 3Q93A 1JRKA 2ICKA 3COUA 3O8SA 5FSLA 5IW4A 5LPGA 2A8RA 5ISYA 2G74A 5CFJA 1VRLA 3I7UA 1HX3A 3X0SA 4J7HA 1VC9A 3Q91A 2B0VA 3BM4A 2GB5A 3OGAA 5GHMA 1V8SA 5GHIA 2QJOA 5FSNA 2W4EA 4N1TA 4HVYA 3MDGA 1Q27A 3GG6A 4MPOA 3Q2TA 1V8TA 5ANWA 1V8IA 1HZTA 1PUQA 1PVFA 1KHZA 1X84A 2VNPA 3FJYA 2YVPA 3E57A 2QKMB 1VIUA 3FSPA 1K2EA 1NQZA 1RRQA 3QSJA 1VCDA 1MQEA 2JVBA 2AZWA 3I9XA 2VNQA 3ID9A 2YVNA 5DEQA 3EEUA 1GA7A 3SMDA 2B2KA 5FSOA 1JKNA 1V8RA 3GZ5A 4DYWA 4HFQA 3HHJA 1V8UA 2A8QA 3BHOA 2ICJA 1U20A 5ANSA 5C8LA 5BONA 2DSDA 4S2WA 4YPHA 3L85A 3Q4IA 2G73A 2GT2A 3EESA 3O6ZA 5C7QA 5CFIA 4KTBA 1Q33A 5FSIA 4JZUA 3X0QA 2PQVA 5ANTA 3O52A 3Q2SA 4KYXA 3X0NA 1VC8A 4YOQA 2Q9PA 3Q1PA 1X51A 4JZSA 1X83A 2I6KA 2KDVA 5BS6A 3DUPA 4ILQA 4V14A 1V8VA 4ZG0A 3ACAA 1F3YA 5GHJA 2O5WA 1KT9A 3N9UA 1KTGA 4IJXA 1SZ3A 1OW2A 5GHOA 5GHPA 3KVHA 3GZ6A 2CZRA 2DSBA 1XSCA 3GZ8A 3F6AA 4C9XA 5GHQA 4S2XA 3GRNA 2GT4A 3O69A 4YPRA 1PPWA 1XSAA 1G9QA 4S2VA 2YVOA 1RRSA 5ANUA 1PPXA 2I8TA 1MQWA 4NFWA 2A8SA 4NFXA 5GHNA 3U53A 3ZR0A 2J8QA 3N77A 1XSBA 3H95A 5I8UA 1RYAA 1V8LA 4JZTA 2FMLA 2O1CA 3X0PA 1Q54A 3X0IA 1V8WA 5DDGA 2DHOA 5C7TA 3HYQA 1MK1A 4ICKA 3SONA 4C9WA 3AC9A 2CL3A 2A6TA 2YVMA 1V8MA 2YYHA 1MUTA 1NQYA 1NFZA 1VHGA 2A8PA 3EXQA 5FSKA 5FSMA 4S2YA 3GWYA 3A6UA 3DKUA 3X0LA 1V8YA 3MGMA 5IW5A 3A6VA 2FVVA 3MCFA 2DSCA 2PNYA 3FCMA 5ANVA 1MR2A 1VIQA 3CNGA 3WHWA 3X0OA 3X0JA 1IRYA 1QVJA 1SU2A 3P5TA 1VHZA 4KG4A 2RRKA 3X0MA 3J7Ye 4K6EA 3FFUA 3A6TA 2QJTA 5DPKA 3RH7A 3I7VA 1VK6A 1NFSA 2KDWA 1PUNA 3P6YA 4N1UA 3SHDA 1R67A 2B06A 1TUMA 2DUKA 1SOIA 4KG3A 5HZXA 3MDIA 3G0QA 3A6SA 2R5WA 1SJYA 3EF5A 3F13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J7H A;  4J7G A; 
#chains in the Genus database with same CATH topology
 3FK9 A;  2O5F A;  3X0R A;  3ZR1 A;  2XSQ A;  1V8N A;  2I8U A;  4J7G A;  1MP2 A;  2A8T A;  1G0S A;  3BAP A;  4JZV A;  1I9A A;  1K26 A;  3O61 A;  3R03 A;  1PPV A;  5DD4 A;  3X0K A;  1PUS A;  2FKB A;  3Q93 A;  1JRK A;  2ICK A;  3COU A;  3O8S A;  5FSL A;  5IW4 A;  5LPG A;  2A8R A;  5ISY A;  2G74 A;  5CFJ A;  1VRL A;  3I7U A;  1HX3 A;  3X0S A;  4J7H A;  1VC9 A;  3Q91 A;  2B0V A;  3BM4 A;  2GB5 A;  3OGA A;  5GHM A;  1V8S A;  5GHI A;  2QJO A;  5FSN A;  2W4E A;  4N1T A;  4HVY A;  3MDG A;  1Q27 A;  3GG6 A;  4MPO A;  3Q2T A;  1V8T A;  5ANW A;  1V8I A;  1HZT A;  1PUQ A;  1PVF A;  1KHZ A;  1X84 A;  2VNP A;  3FJY A;  2YVP A;  3E57 A;  2QKM B;  1VIU A;  3FSP A;  1K2E A;  1NQZ A;  1RRQ A;  3QSJ A;  1VCD A;  1MQE A;  2JVB A;  2AZW A;  3I9X A;  2VNQ A;  3ID9 A;  2YVN A;  5DEQ A;  3EEU A;  1GA7 A;  3SMD A;  2B2K A;  5FSO A;  1JKN A;  1V8R A;  3GZ5 A;  4DYW A;  4HFQ A;  3HHJ A;  1V8U A;  2A8Q A;  3BHO A;  2ICJ A;  1U20 A;  5ANS A;  5C8L A;  5BON A;  2DSD A;  4S2W A;  4YPH A;  3L85 A;  3Q4I A;  2G73 A;  2GT2 A;  3EES A;  3O6Z A;  5C7Q A;  5CFI A;  4KTB A;  1Q33 A;  5FSI A;  4JZU A;  3X0Q A;  2PQV A;  5ANT A;  3O52 A;  3Q2S A;  4KYX A;  3X0N A;  1VC8 A;  4YOQ A;  2Q9P A;  3Q1P A;  1X51 A;  4JZS A;  1X83 A;  2I6K A;  2KDV A;  5BS6 A;  3DUP A;  4ILQ A;  4V14 A;  1V8V A;  4ZG0 A;  3ACA A;  1F3Y A;  5GHJ A;  2O5W A;  1KT9 A;  3N9U A;  1KTG A;  4IJX A;  1SZ3 A;  1OW2 A;  5GHO A;  5GHP A;  3KVH A;  3GZ6 A;  2CZR A;  2DSB A;  1XSC A;  3GZ8 A;  3F6A A;  4C9X A;  5GHQ A;  4S2X A;  3GRN A;  2GT4 A;  3O69 A;  4YPR A;  1PPW A;  1XSA A;  1G9Q A;  4S2V A;  2YVO A;  1RRS A;  5ANU A;  1PPX A;  2I8T A;  1MQW A;  4NFW A;  2A8S A;  4NFX A;  5GHN A;  3U53 A;  3ZR0 A;  2J8Q A;  3N77 A;  1XSB A;  3H95 A;  5I8U A;  1RYA A;  1V8L A;  4JZT A;  2FML A;  2O1C A;  3X0P A;  1Q54 A;  3X0I A;  1V8W A;  5DDG A;  2DHO A;  5C7T A;  3HYQ A;  1MK1 A;  4ICK A;  3SON A;  4C9W A;  3AC9 A;  2CL3 A;  2A6T A;  2YVM A;  1V8M A;  2YYH A;  1MUT A;  1NQY A;  1NFZ A;  1VHG A;  2A8P A;  3EXQ A;  5FSK A;  5FSM A;  4S2Y A;  3GWY A;  3A6U A;  3DKU A;  3X0L A;  1V8Y A;  3MGM A;  5IW5 A;  3A6V A;  2FVV A;  3MCF A;  2DSC A;  2PNY A;  3FCM A;  5ANV A;  1MR2 A;  1VIQ A;  3CNG A;  3WHW A;  3X0O A;  3X0J A;  1IRY A;  1QVJ A;  1SU2 A;  3P5T A;  1VHZ A;  4KG4 A;  2RRK A;  3X0M A;  3J7Y e;  4K6E A;  3FFU A;  3A6T A;  2QJT A;  5DPK A;  3RH7 A;  3I7V A;  1VK6 A;  1NFS A;  2KDW A;  1PUN A;  3P6Y A;  4N1U A;  3SHD A;  1R67 A;  2B06 A;  1TUM A;  2DUK A;  1SOI A;  4KG3 A;  5HZX A;  3MDI A;  3G0Q A;  3A6S A;  2R5W A;  1SJY A;  3EF5 A;  3F13 A; 
#chains in the Genus database with same CATH homology
 3FK9 A;  2O5F A;  3X0R A;  3ZR1 A;  2XSQ A;  1V8N A;  2I8U A;  4J7G A;  1MP2 A;  2A8T A;  1G0S A;  3BAP A;  4JZV A;  1I9A A;  1K26 A;  3O61 A;  3R03 A;  1PPV A;  5DD4 A;  3X0K A;  1PUS A;  2FKB A;  3Q93 A;  1JRK A;  2ICK A;  3COU A;  3O8S A;  5FSL A;  5IW4 A;  5LPG A;  2A8R A;  5ISY A;  2G74 A;  5CFJ A;  1VRL A;  3I7U A;  1HX3 A;  3X0S A;  4J7H A;  1VC9 A;  3Q91 A;  2B0V A;  3BM4 A;  2GB5 A;  3OGA A;  5GHM A;  1V8S A;  5GHI A;  2QJO A;  5FSN A;  2W4E A;  4N1T A;  4HVY A;  3MDG A;  1Q27 A;  3GG6 A;  4MPO A;  3Q2T A;  1V8T A;  5ANW A;  1V8I A;  1HZT A;  1PUQ A;  1PVF A;  1KHZ A;  1X84 A;  2VNP A;  3FJY A;  2YVP A;  3E57 A;  2QKM B;  1VIU A;  3FSP A;  1K2E A;  1NQZ A;  1RRQ A;  3QSJ A;  1VCD A;  1MQE A;  2JVB A;  2AZW A;  3I9X A;  2VNQ A;  3ID9 A;  2YVN A;  5DEQ A;  3EEU A;  1GA7 A;  3SMD A;  2B2K A;  5FSO A;  1JKN A;  1V8R A;  3GZ5 A;  4DYW A;  4HFQ A;  3HHJ A;  1V8U A;  2A8Q A;  3BHO A;  2ICJ A;  1U20 A;  5ANS A;  5C8L A;  5BON A;  2DSD A;  4S2W A;  4YPH A;  3L85 A;  3Q4I A;  2G73 A;  2GT2 A;  3EES A;  3O6Z A;  5C7Q A;  5CFI A;  4KTB A;  1Q33 A;  5FSI A;  4JZU A;  3X0Q A;  2PQV A;  5ANT A;  3O52 A;  3Q2S A;  4KYX A;  3X0N A;  1VC8 A;  4YOQ A;  2Q9P A;  3Q1P A;  1X51 A;  4JZS A;  1X83 A;  2I6K A;  2KDV A;  5BS6 A;  3DUP A;  4ILQ A;  4V14 A;  1V8V A;  4ZG0 A;  3ACA A;  1F3Y A;  5GHJ A;  2O5W A;  1KT9 A;  3N9U A;  1KTG A;  4IJX A;  1SZ3 A;  1OW2 A;  5GHO A;  5GHP A;  3KVH A;  3GZ6 A;  2CZR A;  2DSB A;  1XSC A;  3GZ8 A;  3F6A A;  4C9X A;  5GHQ A;  4S2X A;  3GRN A;  2GT4 A;  3O69 A;  4YPR A;  1PPW A;  1XSA A;  1G9Q A;  4S2V A;  2YVO A;  1RRS A;  5ANU A;  1PPX A;  2I8T A;  1MQW A;  4NFW A;  2A8S A;  4NFX A;  5GHN A;  3U53 A;  3ZR0 A;  2J8Q A;  3N77 A;  1XSB A;  3H95 A;  5I8U A;  1RYA A;  1V8L A;  4JZT A;  2FML A;  2O1C A;  3X0P A;  1Q54 A;  3X0I A;  1V8W A;  5DDG A;  2DHO A;  5C7T A;  3HYQ A;  1MK1 A;  4ICK A;  3SON A;  4C9W A;  3AC9 A;  2CL3 A;  2A6T A;  2YVM A;  1V8M A;  2YYH A;  1MUT A;  1NQY A;  1NFZ A;  1VHG A;  2A8P A;  3EXQ A;  5FSK A;  5FSM A;  4S2Y A;  3GWY A;  3A6U A;  3DKU A;  3X0L A;  1V8Y A;  3MGM A;  5IW5 A;  3A6V A;  2FVV A;  3MCF A;  2DSC A;  2PNY A;  3FCM A;  5ANV A;  1MR2 A;  1VIQ A;  3CNG A;  3WHW A;  3X0O A;  3X0J A;  1IRY A;  1QVJ A;  1SU2 A;  3P5T A;  1VHZ A;  4KG4 A;  2RRK A;  3X0M A;  3J7Y e;  4K6E A;  3FFU A;  3A6T A;  2QJT A;  5DPK A;  3RH7 A;  3I7V A;  1VK6 A;  1NFS A;  2KDW A;  1PUN A;  3P6Y A;  4N1U A;  3SHD A;  1R67 A;  2B06 A;  1TUM A;  2DUK A;  1SOI A;  4KG3 A;  5HZX A;  3MDI A;  3G0Q A;  3A6S A;  2R5W A;  1SJY A;  3EF5 A;  3F13 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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