4J7GA

Crystal structure of evaa, a 2,3-dehydratase in complex with dtdp-fucose and dtdp-rhamnose
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
458
structure length
448
Chain Sequence
AVRPRDHHDYADRIALSAATTDGVQMRTEDVRAWIAERRDANVFHVERIPFADLDQWWFEGVTGNLVHRSGRFFTIEGLHVIEHDGPHGDGPYREWQQPVIRQPEVGILGILAKEFDGVLHFLMQAKMEPGNPNLVQLSPTVQATRSNYTNVKLIEYFAPPDPERVIVDVLQAEQGSWFFRKSNRNMIVETVDDVPLWDDFCWLTLGQIAELMHEDETINMNSRSVLSCLPYQDITPRALFSDVQLLSWFTNERSRHDVRVRRIPLADVCGWKQGAEEIEHEDGRYFKVLAVAVKGSISWTQPLVESVDLGVVAFLVRKIDGVPHVLVQARVDGGFLDTVELAPTVQCTPLNYAHLPAEEAPPFLDLVQNAPRSRIRYEAIHSEEGGRFLGVRARYLVIDADEAIDPPPGYAWVTPAQLTALTRHGHYVNVEARTLLACINAAAAQPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
pubmed doi rcsb
molecule keywords EvaA 2,3-dehydratase
molecule tags Biosynthetic protein
source organism Amycolatopsis orientalis
total genus 135
structure length 448
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.2.1.159: dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase.
pdb deposition date 2013-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03559 Hexose_dehydrat NDP-hexose 2,3-dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.79.40 Alpha Beta Alpha-Beta Complex Nucleoside Triphosphate Pyrophosphohydrolase Nucleoside Triphosphate Pyrophosphohydrolase 4j7gA02
4J7GA 4J7HA
chains in the Genus database with same CATH superfamily
2A8PA 1NQZA 2A8RA 3GWYA 3SMDA 1NFZA 2AZWA 1PPWA 2QKMB 1V8IA 2B2KA 3I7VA 4JZUA 1RRSA 3Q93A 1XSAA 1PUNA 1VIUA 1V8VA 5FSKA 2J8QA 3QSJA 3FJYA 3X0IA 3SHDA 1JRKA 1Q54A 1X84A 4J7HA 3Q2SA 1X51A 5C7QA 3MDGA 3A6VA 3FK9A 3GG6A 2YVPA 4JZVA 3N9UA 2YVMA 3X0MA 2I8TA 4S2XA 1SZ3A 2GB5A 3X0KA 1V8LA 3X0NA 1JKNA 1V8YA 4NFWA 1V8NA 2FKBA 5I8UA 3X0PA 1MUTA 2DSDA 1MQEA 2A6TA 3EF5A 4S2VA 1NQYA 4V14A 2A8TA 3I9XA 5CFJA 3GZ6A 2B0VA 2Q9PA 2QJTA 4KG3A 2DUKA 4KG4A 1V8SA 4ICKA 5CFIA 1PUQA 2O5WA 3HHJA 5GHIA 5FSIA 3KVHA 1MK1A 3GRNA 1VRLA 3AC9A 1VC8A 4N1TA 1TUMA 3DUPA 3L85A 3O61A 1PVFA 1VCDA 3X0LA 3J7Ye 3BAPA 3BHOA 3X0QA 3N77A 5FSNA 3FFUA 3GZ8A 3MGMA 5ANUA 1RRQA 5FSLA 1KT9A 1VC9A 1XSBA 3EESA 2A8QA 1RYAA 5DD4A 3E57A 3I7UA 3X0SA 3X0RA 2XSQA 5FSMA 2FMLA 2DHOA 2O5FA 3H95A 1V8RA 1V8WA 5C7TA 1IRYA 2JVBA 3SONA 2FVVA 5DPKA 3ACAA 2I8UA 3WHWA 4HFQA 3ZR0A 1X83A 3Q1PA 3MDIA 2ICKA 2PNYA 2YYHA 4JZTA 4N1UA 2G74A 5ANSA 1SOIA 3FCMA 3P5TA 3F13A 4HVYA 1F3YA 5ANWA 3RH7A 4KYXA 1Q33A 3BM4A 1K2EA 3O8SA 2VNPA 3EEUA 1MR2A 1SU2A 1PUSA 4YPRA 1KTGA 1MQWA 5GHMA 4C9XA 3DKUA 5GHOA 1VIQA 5DEQA 4DYWA 1PPXA 2O1CA 2DSBA 3ZR1A 3A6SA 3ID9A 2GT4A 3X0JA 1GA7A 1SJYA 3R03A 4K6EA 1U20A 5ANVA 3A6UA 2G73A 4ZG0A 5DDGA 5LPGA 4S2YA 3COUA 5GHPA 3Q2TA 2R5WA 5C8LA 5GHNA 1KHZA 3GZ5A 3O69A 2YVNA 3FSPA 5GHQA 1OW2A 2W4EA 5BS6A 1HX3A 1VK6A 3P6YA 5IW4A 1XSCA 4MPOA 1QVJA 1NFSA 3MCFA 3U53A 1R67A 1HZTA 2I6KA 2B06A 4ILQA 4NFXA 3Q91A 1V8UA 2YVOA 4S2WA 3X0OA 4C9WA 4JZSA 3A6TA 3HYQA 3O52A 3G0QA 1VHZA 4KTBA 3Q4IA 2CL3A 4J7GA 5GHJA 2KDWA 2QJOA 1I9AA 3O6ZA 1K26A 4YOQA 1VHGA 1MP2A 3CNGA 5ANTA 2PQVA 3F6AA 2DSCA 3OGAA 4IJXA 5IW5A 5FSOA 2RRKA 5ISYA 2CZRA 5BONA 4YPHA 1V8MA 2A8SA 5HZXA 1PPVA 2KDVA 1V8TA 2GT2A 1G9QA 1G0SA 2ICJA 2VNQA 1Q27A 3EXQA
chains in the Genus database with same CATH topology
2A8PA 1NQZA 2A8RA 3GWYA 3SMDA 1NFZA 2AZWA 1PPWA 2QKMB 1V8IA 2B2KA 3I7VA 4JZUA 1RRSA 3Q93A 1XSAA 1PUNA 1VIUA 1V8VA 5FSKA 2J8QA 3QSJA 3FJYA 3X0IA 3SHDA 1JRKA 1Q54A 1X84A 4J7HA 3Q2SA 1X51A 5C7QA 3MDGA 3A6VA 3FK9A 3GG6A 2YVPA 4JZVA 3N9UA 2YVMA 3X0MA 2I8TA 4S2XA 1SZ3A 2GB5A 3X0KA 1V8LA 3X0NA 1JKNA 1V8YA 4NFWA 1V8NA 2FKBA 5I8UA 3X0PA 1MUTA 2DSDA 1MQEA 2A6TA 3EF5A 4S2VA 1NQYA 4V14A 2A8TA 3I9XA 5CFJA 3GZ6A 2B0VA 2Q9PA 2QJTA 4KG3A 2DUKA 4KG4A 1V8SA 4ICKA 5CFIA 1PUQA 2O5WA 3HHJA 5GHIA 5FSIA 3KVHA 1MK1A 3GRNA 1VRLA 3AC9A 1VC8A 4N1TA 1TUMA 3DUPA 3L85A 3O61A 1PVFA 1VCDA 3X0LA 3J7Ye 3BAPA 3BHOA 3X0QA 3N77A 5FSNA 3FFUA 3GZ8A 3MGMA 5ANUA 1RRQA 5FSLA 1KT9A 1VC9A 1XSBA 3EESA 2A8QA 1RYAA 5DD4A 3E57A 3I7UA 3X0SA 3X0RA 2XSQA 5FSMA 2FMLA 2DHOA 2O5FA 3H95A 1V8RA 1V8WA 5C7TA 1IRYA 2JVBA 3SONA 2FVVA 5DPKA 3ACAA 2I8UA 3WHWA 4HFQA 3ZR0A 1X83A 3Q1PA 3MDIA 2ICKA 2PNYA 2YYHA 4JZTA 4N1UA 2G74A 5ANSA 1SOIA 3FCMA 3P5TA 3F13A 4HVYA 1F3YA 5ANWA 3RH7A 4KYXA 1Q33A 3BM4A 1K2EA 3O8SA 2VNPA 3EEUA 1MR2A 1SU2A 1PUSA 4YPRA 1KTGA 1MQWA 5GHMA 4C9XA 3DKUA 5GHOA 1VIQA 5DEQA 4DYWA 1PPXA 2O1CA 2DSBA 3ZR1A 3A6SA 3ID9A 2GT4A 3X0JA 1GA7A 1SJYA 3R03A 4K6EA 1U20A 5ANVA 3A6UA 2G73A 4ZG0A 5DDGA 5LPGA 4S2YA 3COUA 5GHPA 3Q2TA 2R5WA 5C8LA 5GHNA 1KHZA 3GZ5A 3O69A 2YVNA 3FSPA 5GHQA 1OW2A 2W4EA 5BS6A 1HX3A 1VK6A 3P6YA 5IW4A 1XSCA 4MPOA 1QVJA 1NFSA 3MCFA 3U53A 1R67A 1HZTA 2I6KA 2B06A 4ILQA 4NFXA 3Q91A 1V8UA 2YVOA 4S2WA 3X0OA 4C9WA 4JZSA 3A6TA 3HYQA 3O52A 3G0QA 1VHZA 4KTBA 3Q4IA 2CL3A 4J7GA 5GHJA 2KDWA 2QJOA 1I9AA 3O6ZA 1K26A 4YOQA 1VHGA 1MP2A 3CNGA 5ANTA 2PQVA 3F6AA 2DSCA 3OGAA 4IJXA 5IW5A 5FSOA 2RRKA 5ISYA 2CZRA 5BONA 4YPHA 1V8MA 2A8SA 5HZXA 1PPVA 2KDVA 1V8TA 2GT2A 1G9QA 1G0SA 2ICJA 2VNQA 1Q27A 3EXQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J7G A;  4J7H A; 
#chains in the Genus database with same CATH topology
 2A8P A;  1NQZ A;  2A8R A;  3GWY A;  3SMD A;  1NFZ A;  2AZW A;  1PPW A;  2QKM B;  1V8I A;  2B2K A;  3I7V A;  4JZU A;  1RRS A;  3Q93 A;  1XSA A;  1PUN A;  1VIU A;  1V8V A;  5FSK A;  2J8Q A;  3QSJ A;  3FJY A;  3X0I A;  3SHD A;  1JRK A;  1Q54 A;  1X84 A;  4J7H A;  3Q2S A;  1X51 A;  5C7Q A;  3MDG A;  3A6V A;  3FK9 A;  3GG6 A;  2YVP A;  4JZV A;  3N9U A;  2YVM A;  3X0M A;  2I8T A;  4S2X A;  1SZ3 A;  2GB5 A;  3X0K A;  1V8L A;  3X0N A;  1JKN A;  1V8Y A;  4NFW A;  1V8N A;  2FKB A;  5I8U A;  3X0P A;  1MUT A;  2DSD A;  1MQE A;  2A6T A;  3EF5 A;  4S2V A;  1NQY A;  4V14 A;  2A8T A;  3I9X A;  5CFJ A;  3GZ6 A;  2B0V A;  2Q9P A;  2QJT A;  4KG3 A;  2DUK A;  4KG4 A;  1V8S A;  4ICK A;  5CFI A;  1PUQ A;  2O5W A;  3HHJ A;  5GHI A;  5FSI A;  3KVH A;  1MK1 A;  3GRN A;  1VRL A;  3AC9 A;  1VC8 A;  4N1T A;  1TUM A;  3DUP A;  3L85 A;  3O61 A;  1PVF A;  1VCD A;  3X0L A;  3J7Y e;  3BAP A;  3BHO A;  3X0Q A;  3N77 A;  5FSN A;  3FFU A;  3GZ8 A;  3MGM A;  5ANU A;  1RRQ A;  5FSL A;  1KT9 A;  1VC9 A;  1XSB A;  3EES A;  2A8Q A;  1RYA A;  5DD4 A;  3E57 A;  3I7U A;  3X0S A;  3X0R A;  2XSQ A;  5FSM A;  2FML A;  2DHO A;  2O5F A;  3H95 A;  1V8R A;  1V8W A;  5C7T A;  1IRY A;  2JVB A;  3SON A;  2FVV A;  5DPK A;  3ACA A;  2I8U A;  3WHW A;  4HFQ A;  3ZR0 A;  1X83 A;  3Q1P A;  3MDI A;  2ICK A;  2PNY A;  2YYH A;  4JZT A;  4N1U A;  2G74 A;  5ANS A;  1SOI A;  3FCM A;  3P5T A;  3F13 A;  4HVY A;  1F3Y A;  5ANW A;  3RH7 A;  4KYX A;  1Q33 A;  3BM4 A;  1K2E A;  3O8S A;  2VNP A;  3EEU A;  1MR2 A;  1SU2 A;  1PUS A;  4YPR A;  1KTG A;  1MQW A;  5GHM A;  4C9X A;  3DKU A;  5GHO A;  1VIQ A;  5DEQ A;  4DYW A;  1PPX A;  2O1C A;  2DSB A;  3ZR1 A;  3A6S A;  3ID9 A;  2GT4 A;  3X0J A;  1GA7 A;  1SJY A;  3R03 A;  4K6E A;  1U20 A;  5ANV A;  3A6U A;  2G73 A;  4ZG0 A;  5DDG A;  5LPG A;  4S2Y A;  3COU A;  5GHP A;  3Q2T A;  2R5W A;  5C8L A;  5GHN A;  1KHZ A;  3GZ5 A;  3O69 A;  2YVN A;  3FSP A;  5GHQ A;  1OW2 A;  2W4E A;  5BS6 A;  1HX3 A;  1VK6 A;  3P6Y A;  5IW4 A;  1XSC A;  4MPO A;  1QVJ A;  1NFS A;  3MCF A;  3U53 A;  1R67 A;  1HZT A;  2I6K A;  2B06 A;  4ILQ A;  4NFX A;  3Q91 A;  1V8U A;  2YVO A;  4S2W A;  3X0O A;  4C9W A;  4JZS A;  3A6T A;  3HYQ A;  3O52 A;  3G0Q A;  1VHZ A;  4KTB A;  3Q4I A;  2CL3 A;  4J7G A;  5GHJ A;  2KDW A;  2QJO A;  1I9A A;  3O6Z A;  1K26 A;  4YOQ A;  1VHG A;  1MP2 A;  3CNG A;  5ANT A;  2PQV A;  3F6A A;  2DSC A;  3OGA A;  4IJX A;  5IW5 A;  5FSO A;  2RRK A;  5ISY A;  2CZR A;  5BON A;  4YPH A;  1V8M A;  2A8S A;  5HZX A;  1PPV A;  2KDV A;  1V8T A;  2GT2 A;  1G9Q A;  1G0S A;  2ICJ A;  2VNQ A;  1Q27 A;  3EXQ A; 
#chains in the Genus database with same CATH homology
 2A8P A;  1NQZ A;  2A8R A;  3GWY A;  3SMD A;  1NFZ A;  2AZW A;  1PPW A;  2QKM B;  1V8I A;  2B2K A;  3I7V A;  4JZU A;  1RRS A;  3Q93 A;  1XSA A;  1PUN A;  1VIU A;  1V8V A;  5FSK A;  2J8Q A;  3QSJ A;  3FJY A;  3X0I A;  3SHD A;  1JRK A;  1Q54 A;  1X84 A;  4J7H A;  3Q2S A;  1X51 A;  5C7Q A;  3MDG A;  3A6V A;  3FK9 A;  3GG6 A;  2YVP A;  4JZV A;  3N9U A;  2YVM A;  3X0M A;  2I8T A;  4S2X A;  1SZ3 A;  2GB5 A;  3X0K A;  1V8L A;  3X0N A;  1JKN A;  1V8Y A;  4NFW A;  1V8N A;  2FKB A;  5I8U A;  3X0P A;  1MUT A;  2DSD A;  1MQE A;  2A6T A;  3EF5 A;  4S2V A;  1NQY A;  4V14 A;  2A8T A;  3I9X A;  5CFJ A;  3GZ6 A;  2B0V A;  2Q9P A;  2QJT A;  4KG3 A;  2DUK A;  4KG4 A;  1V8S A;  4ICK A;  5CFI A;  1PUQ A;  2O5W A;  3HHJ A;  5GHI A;  5FSI A;  3KVH A;  1MK1 A;  3GRN A;  1VRL A;  3AC9 A;  1VC8 A;  4N1T A;  1TUM A;  3DUP A;  3L85 A;  3O61 A;  1PVF A;  1VCD A;  3X0L A;  3J7Y e;  3BAP A;  3BHO A;  3X0Q A;  3N77 A;  5FSN A;  3FFU A;  3GZ8 A;  3MGM A;  5ANU A;  1RRQ A;  5FSL A;  1KT9 A;  1VC9 A;  1XSB A;  3EES A;  2A8Q A;  1RYA A;  5DD4 A;  3E57 A;  3I7U A;  3X0S A;  3X0R A;  2XSQ A;  5FSM A;  2FML A;  2DHO A;  2O5F A;  3H95 A;  1V8R A;  1V8W A;  5C7T A;  1IRY A;  2JVB A;  3SON A;  2FVV A;  5DPK A;  3ACA A;  2I8U A;  3WHW A;  4HFQ A;  3ZR0 A;  1X83 A;  3Q1P A;  3MDI A;  2ICK A;  2PNY A;  2YYH A;  4JZT A;  4N1U A;  2G74 A;  5ANS A;  1SOI A;  3FCM A;  3P5T A;  3F13 A;  4HVY A;  1F3Y A;  5ANW A;  3RH7 A;  4KYX A;  1Q33 A;  3BM4 A;  1K2E A;  3O8S A;  2VNP A;  3EEU A;  1MR2 A;  1SU2 A;  1PUS A;  4YPR A;  1KTG A;  1MQW A;  5GHM A;  4C9X A;  3DKU A;  5GHO A;  1VIQ A;  5DEQ A;  4DYW A;  1PPX A;  2O1C A;  2DSB A;  3ZR1 A;  3A6S A;  3ID9 A;  2GT4 A;  3X0J A;  1GA7 A;  1SJY A;  3R03 A;  4K6E A;  1U20 A;  5ANV A;  3A6U A;  2G73 A;  4ZG0 A;  5DDG A;  5LPG A;  4S2Y A;  3COU A;  5GHP A;  3Q2T A;  2R5W A;  5C8L A;  5GHN A;  1KHZ A;  3GZ5 A;  3O69 A;  2YVN A;  3FSP A;  5GHQ A;  1OW2 A;  2W4E A;  5BS6 A;  1HX3 A;  1VK6 A;  3P6Y A;  5IW4 A;  1XSC A;  4MPO A;  1QVJ A;  1NFS A;  3MCF A;  3U53 A;  1R67 A;  1HZT A;  2I6K A;  2B06 A;  4ILQ A;  4NFX A;  3Q91 A;  1V8U A;  2YVO A;  4S2W A;  3X0O A;  4C9W A;  4JZS A;  3A6T A;  3HYQ A;  3O52 A;  3G0Q A;  1VHZ A;  4KTB A;  3Q4I A;  2CL3 A;  4J7G A;  5GHJ A;  2KDW A;  2QJO A;  1I9A A;  3O6Z A;  1K26 A;  4YOQ A;  1VHG A;  1MP2 A;  3CNG A;  5ANT A;  2PQV A;  3F6A A;  2DSC A;  3OGA A;  4IJX A;  5IW5 A;  5FSO A;  2RRK A;  5ISY A;  2CZR A;  5BON A;  4YPH A;  1V8M A;  2A8S A;  5HZX A;  1PPV A;  2KDV A;  1V8T A;  2GT2 A;  1G9Q A;  1G0S A;  2ICJ A;  2VNQ A;  1Q27 A;  3EXQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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