4J93A

Crystal structure of the n-terminal domain of hiv-1 capsid in complex with inhibitor bi-1
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes.
pubmed doi rcsb
molecule tags Viral protein/viral protein inhibitor
source organism Human immunodeficiency virus 1
molecule keywords Gag protein
total genus 50
structure length 146
sequence length 146
ec nomenclature
pdb deposition date 2013-02-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4j93A00
1QRJA 2XDEA 4J93A 4QNBA 4E92A 1G03A 4PH2A 2M8PA 4U0DA 1D1DA 2JPRA 4XROA 5HGLA 4B4NA 2Y4ZA 1GWPA 1M9EC 5HGNA 4INBA 1P7NA 2LF4A 1EM9A 1AFVA 2KGFA 1U7KA 2WLVB 3NTEA 2X2DD 4NX4C 4PH3A 2V4XA 1M9DC 4DGAC 2WLVA 2M8NA 1E6JP 1AK4C 4XFZA 3H47A 4XFYA 4DGEC 1M9YC 5HGKA 4E91A 1EIAA 4U0CA 2XGVA 1M9CC 2PWOA 4XRQA 2PWMA 1L6NA 4LQWC 3BP9A 4U0FA 5HGMA 4PH0A 2M8LA 2GOLB 4U0EA 1M9FC 2GONA 4HTWA 3P05A 2XGYA 2PXRC 4U0BA 2X82A 1M9XC 2X83A 4XFXA 5JPAA 2EIAA 3H4EA 5HGOA 3MGEA 4WYMA 4U0AA 2XGUA
chains in the Genus database with same CATH superfamily
1QRJA 2XDEA 4J93A 4QNBA 4E92A 1G03A 4PH2A 2M8PA 4U0DA 1D1DA 2JPRA 4XROA 5HGLA 4B4NA 2Y4ZA 1GWPA 1M9EC 5HGNA 4INBA 1P7NA 2LF4A 1EM9A 1AFVA 2KGFA 1U7KA 2WLVB 3NTEA 2X2DD 4NX4C 4PH3A 2V4XA 1M9DC 4DGAC 2WLVA 2M8NA 1E6JP 1AK4C 4XFZA 3H47A 4XFYA 4DGEC 1M9YC 5HGKA 4E91A 1EIAA 4U0CA 2XGVA 1M9CC 2PWOA 4XRQA 2PWMA 1L6NA 4LQWC 3BP9A 4U0FA 5HGMA 4PH0A 2M8LA 2GOLB 4U0EA 1M9FC 2GONA 4HTWA 3P05A 2XGYA 2PXRC 4U0BA 2X82A 1M9XC 2X83A 4XFXA 5JPAA 2EIAA 3H4EA 5HGOA 3MGEA 4WYMA 4U0AA 2XGUA
chains in the Genus database with same CATH topology
1QRJA 2XDEA 4J93A 4QNBA 4E92A 1G03A 4PH2A 2M8PA 4U0DA 1D1DA 2JPRA 4XROA 5HGLA 4B4NA 2Y4ZA 1GWPA 1M9EC 5HGNA 4INBA 1P7NA 2LF4A 1EM9A 1AFVA 2KGFA 1U7KA 2WLVB 3NTEA 2X2DD 4NX4C 4PH3A 2V4XA 1M9DC 4DGAC 2WLVA 2M8NA 1E6JP 1AK4C 4XFZA 3H47A 4XFYA 4DGEC 1M9YC 5HGKA 4E91A 1EIAA 4U0CA 2XGVA 1M9CC 2PWOA 4XRQA 2PWMA 1L6NA 4LQWC 3BP9A 4U0FA 5HGMA 4PH0A 2M8LA 2GOLB 4U0EA 1M9FC 2GONA 4HTWA 3P05A 2XGYA 2PXRC 4U0BA 2X82A 1M9XC 2X83A 4XFXA 5JPAA 2EIAA 3H4EA 5HGOA 3MGEA 4WYMA 4U0AA 2XGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QRJ A;  2XDE A;  4J93 A;  4QNB A;  4E92 A;  1G03 A;  4PH2 A;  2M8P A;  4U0D A;  1D1D A;  2JPR A;  4XRO A;  5HGL A;  4B4N A;  2Y4Z A;  1GWP A;  1M9E C;  5HGN A;  4INB A;  1P7N A;  2LF4 A;  1EM9 A;  1AFV A;  2KGF A;  1U7K A;  2WLV B;  3NTE A;  2X2D D;  4NX4 C;  4PH3 A;  2V4X A;  1M9D C;  4DGA C;  2WLV A;  2M8N A;  1E6J P;  1AK4 C;  4XFZ A;  3H47 A;  4XFY A;  4DGE C;  1M9Y C;  5HGK A;  4E91 A;  1EIA A;  4U0C A;  2XGV A;  1M9C C;  2PWO A;  4XRQ A;  2PWM A;  1L6N A;  4LQW C;  3BP9 A;  4U0F A;  5HGM A;  4PH0 A;  2M8L A;  2GOL B;  4U0E A;  1M9F C;  2GON A;  4HTW A;  3P05 A;  2XGY A;  2PXR C;  4U0B A;  2X82 A;  1M9X C;  2X83 A;  4XFX A;  5JPA A;  2EIA A;  3H4E A;  5HGO A;  3MGE A;  4WYM A;  4U0A A;  2XGU A; 
#chains in the Genus database with same CATH topology
 1QRJ A;  2XDE A;  4J93 A;  4QNB A;  4E92 A;  1G03 A;  4PH2 A;  2M8P A;  4U0D A;  1D1D A;  2JPR A;  4XRO A;  5HGL A;  4B4N A;  2Y4Z A;  1GWP A;  1M9E C;  5HGN A;  4INB A;  1P7N A;  2LF4 A;  1EM9 A;  1AFV A;  2KGF A;  1U7K A;  2WLV B;  3NTE A;  2X2D D;  4NX4 C;  4PH3 A;  2V4X A;  1M9D C;  4DGA C;  2WLV A;  2M8N A;  1E6J P;  1AK4 C;  4XFZ A;  3H47 A;  4XFY A;  4DGE C;  1M9Y C;  5HGK A;  4E91 A;  1EIA A;  4U0C A;  2XGV A;  1M9C C;  2PWO A;  4XRQ A;  2PWM A;  1L6N A;  4LQW C;  3BP9 A;  4U0F A;  5HGM A;  4PH0 A;  2M8L A;  2GOL B;  4U0E A;  1M9F C;  2GON A;  4HTW A;  3P05 A;  2XGY A;  2PXR C;  4U0B A;  2X82 A;  1M9X C;  2X83 A;  4XFX A;  5JPA A;  2EIA A;  3H4E A;  5HGO A;  3MGE A;  4WYM A;  4U0A A;  2XGU A; 
#chains in the Genus database with same CATH homology
 1QRJ A;  2XDE A;  4J93 A;  4QNB A;  4E92 A;  1G03 A;  4PH2 A;  2M8P A;  4U0D A;  1D1D A;  2JPR A;  4XRO A;  5HGL A;  4B4N A;  2Y4Z A;  1GWP A;  1M9E C;  5HGN A;  4INB A;  1P7N A;  2LF4 A;  1EM9 A;  1AFV A;  2KGF A;  1U7K A;  2WLV B;  3NTE A;  2X2D D;  4NX4 C;  4PH3 A;  2V4X A;  1M9D C;  4DGA C;  2WLV A;  2M8N A;  1E6J P;  1AK4 C;  4XFZ A;  3H47 A;  4XFY A;  4DGE C;  1M9Y C;  5HGK A;  4E91 A;  1EIA A;  4U0C A;  2XGV A;  1M9C C;  2PWO A;  4XRQ A;  2PWM A;  1L6N A;  4LQW C;  3BP9 A;  4U0F A;  5HGM A;  4PH0 A;  2M8L A;  2GOL B;  4U0E A;  1M9F C;  2GON A;  4HTW A;  3P05 A;  2XGY A;  2PXR C;  4U0B A;  2X82 A;  1M9X C;  2X83 A;  4XFX A;  5JPA A;  2EIA A;  3H4E A;  5HGO A;  3MGE A;  4WYM A;  4U0A A;  2XGU A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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