4JN5A

Crystal structures of the first condensation domain of the cda synthetase
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
446
structure length
435
Chain Sequence
NSSVRHGLTSAQHEVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Streptomyces coelicolor
molecule keywords CDA peptide synthetase I
total genus 141
structure length 435
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 4jn5A01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 4jn5A02
1EADA 1PD5A 2XR7A 3CLAA 3FOTA 1C4TA 3B30A 5T3EA 1Q23A 5DUAA 1L5AA 5KJSA 2E1TA 4HVMA 2IHWA 2II5A 4KECA 1XMCA 4JN3A 5DU9A 1EABA 2I9DA 1DPDA 4G22A 4KE4A 1EAEA 2RKTA 2VSQA 3U9FA 2RKVA 2CLAA 5KJUA 1XMDA 2BGHA 5KJVA 4N72A 5KJTA 3MAEA 1CIAA 1CLAA 3U9BA 1DPCA 3FP0A 1Q9JA 2ZBAA 4JN5A 1SCZA 4G2MA 2E1VA 2II4A 5FANA 4G0BA 4CLAA 1EAAA 3L60A 1XL8A 2JGPA 5FALA 1E2OA 1NOCB 1EACA 1QCAA 1XL7A 1DPBA 2E1UA 2XHGA 3B2SA 5KJWA 2II3A 1EAFA
chains in the Genus database with same CATH superfamily
1PD5A 3CLAA 1C4TA 1Q23A 2H4TA 5DUAA 1XMCA 1EABA 2I9DA 1NDFA 1EAEA 2VSQA 2BGHA 4N72A 5KJTA 1CLAA 4EP9A 2H3UA 2E1VA 2II4A 4G0BA 2FY3A 1EAAA 2JGPA 2DEBA 5FALA 1NOCB 3B2SA 1T1UA 2II3A 4G2MA 2XR7A 3B30A 4HVMA 2H3PA 1DPDA 4KE4A 1NDBA 2RKVA 5KJUA 1T7OA 2FY5A 4EYWA 3MAEA 1CIAA 3U9BA 1DPCA 4JN5A 1SCZA 5FANA 2FY4A 2RCUA 1E2OA 1Q6XA 1XL7A 1EAFA 1EADA 1L5AA 2IHWA 2II5A 4KECA 4JN3A 5DU9A 1T7QA 1NM8A 1T7NA 3U9FA 2CLAA 4EPHA 5KJVA 2FYOA 2ZBAA 2XHGA 1QCAA 2E1UA 5KJWA 3FOTA 5T3EA 5KJSA 2E1TA 1S5OA 2FW3A 4G22A 2RKTA 1XMDA 3FP0A 1Q9JA 4CLAA 3L60A 2FY2A 1XL8A 2H3WA 1NDIA 1EACA 1DPBA
chains in the Genus database with same CATH topology
1PD5A 3CLAA 1C4TA 1Q23A 5DUAA 2H4TA 1XMCA 1EABA 2I9DA 1NDFA 1EAEA 2VSQA 2BGHA 4N72A 5KJTA 1CLAA 4EP9A 2H3UA 2E1VA 2II4A 4G0BA 2FY3A 1EAAA 2JGPA 2DEBA 5FALA 1NOCB 3B2SA 1T1UA 2II3A 4G2MA 2XR7A 3B30A 4HVMA 2H3PA 1DPDA 4KE4A 1NDBA 2RKVA 5KJUA 1T7OA 2FY5A 4EYWA 3MAEA 1CIAA 3U9BA 1DPCA 4JN5A 1SCZA 5FANA 2FY4A 2RCUA 1E2OA 1Q6XA 1XL7A 1EAFA 1EADA 1L5AA 2IHWA 2II5A 4KECA 4JN3A 5DU9A 1T7QA 1NM8A 1T7NA 3U9FA 2CLAA 4EPHA 5KJVA 2FYOA 2ZBAA 2XHGA 1QCAA 2E1UA 5KJWA 3FOTA 5T3EA 5KJSA 2E1TA 1S5OA 2FW3A 4G22A 2RKTA 1XMDA 3FP0A 1Q9JA 4CLAA 3L60A 2FY2A 1XL8A 2H3WA 1NDIA 1EACA 1DPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAD A;  1PD5 A;  2XR7 A;  3CLA A;  3FOT A;  1C4T A;  3B30 A;  5T3E A;  1Q23 A;  5DUA A;  1L5A A;  5KJS A;  2E1T A;  4HVM A;  2IHW A;  2II5 A;  4KEC A;  1XMC A;  4JN3 A;  5DU9 A;  1EAB A;  2I9D A;  1DPD A;  4G22 A;  4KE4 A;  1EAE A;  2RKT A;  2VSQ A;  3U9F A;  2RKV A;  2CLA A;  5KJU A;  1XMD A;  2BGH A;  5KJV A;  4N72 A;  5KJT A;  3MAE A;  1CIA A;  1CLA A;  3U9B A;  1DPC A;  3FP0 A;  1Q9J A;  2ZBA A;  4JN5 A;  1SCZ A;  4G2M A;  2E1V A;  2II4 A;  5FAN A;  4G0B A;  4CLA A;  1EAA A;  3L60 A;  1XL8 A;  2JGP A;  5FAL A;  1E2O A;  1NOC B;  1EAC A;  1QCA A;  1XL7 A;  1DPB A;  2E1U A;  2XHG A;  3B2S A;  5KJW A;  2II3 A;  1EAF A; 
#chains in the Genus database with same CATH topology
 1PD5 A;  3CLA A;  1C4T A;  1Q23 A;  2H4T A;  5DUA A;  1XMC A;  1EAB A;  2I9D A;  1NDF A;  1EAE A;  2VSQ A;  2BGH A;  4N72 A;  5KJT A;  1CLA A;  4EP9 A;  2H3U A;  2E1V A;  2II4 A;  4G0B A;  2FY3 A;  1EAA A;  2JGP A;  2DEB A;  5FAL A;  1NOC B;  3B2S A;  1T1U A;  2II3 A;  4G2M A;  2XR7 A;  3B30 A;  4HVM A;  2H3P A;  1DPD A;  4KE4 A;  1NDB A;  2RKV A;  5KJU A;  1T7O A;  2FY5 A;  4EYW A;  3MAE A;  1CIA A;  3U9B A;  1DPC A;  4JN5 A;  1SCZ A;  5FAN A;  2FY4 A;  2RCU A;  1E2O A;  1Q6X A;  1XL7 A;  1EAF A;  1EAD A;  1L5A A;  2IHW A;  2II5 A;  4KEC A;  4JN3 A;  5DU9 A;  1T7Q A;  1NM8 A;  1T7N A;  3U9F A;  2CLA A;  4EPH A;  5KJV A;  2FYO A;  2ZBA A;  2XHG A;  1QCA A;  2E1U A;  5KJW A;  3FOT A;  5T3E A;  5KJS A;  2E1T A;  1S5O A;  2FW3 A;  4G22 A;  2RKT A;  1XMD A;  3FP0 A;  1Q9J A;  4CLA A;  3L60 A;  2FY2 A;  1XL8 A;  2H3W A;  1NDI A;  1EAC A;  1DPB A; 
#chains in the Genus database with same CATH homology
 1PD5 A;  3CLA A;  1C4T A;  1Q23 A;  5DUA A;  2H4T A;  1XMC A;  1EAB A;  2I9D A;  1NDF A;  1EAE A;  2VSQ A;  2BGH A;  4N72 A;  5KJT A;  1CLA A;  4EP9 A;  2H3U A;  2E1V A;  2II4 A;  4G0B A;  2FY3 A;  1EAA A;  2JGP A;  2DEB A;  5FAL A;  1NOC B;  3B2S A;  1T1U A;  2II3 A;  4G2M A;  2XR7 A;  3B30 A;  4HVM A;  2H3P A;  1DPD A;  4KE4 A;  1NDB A;  2RKV A;  5KJU A;  1T7O A;  2FY5 A;  4EYW A;  3MAE A;  1CIA A;  3U9B A;  1DPC A;  4JN5 A;  1SCZ A;  5FAN A;  2FY4 A;  2RCU A;  1E2O A;  1Q6X A;  1XL7 A;  1EAF A;  1EAD A;  1L5A A;  2IHW A;  2II5 A;  4KEC A;  4JN3 A;  5DU9 A;  1T7Q A;  1NM8 A;  1T7N A;  3U9F A;  2CLA A;  4EPH A;  5KJV A;  2FYO A;  2ZBA A;  2XHG A;  1QCA A;  2E1U A;  5KJW A;  3FOT A;  5T3E A;  5KJS A;  2E1T A;  1S5O A;  2FW3 A;  4G22 A;  2RKT A;  1XMD A;  3FP0 A;  1Q9J A;  4CLA A;  3L60 A;  2FY2 A;  1XL8 A;  2H3W A;  1NDI A;  1EAC A;  1DPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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