4JN5A

Crystal structures of the first condensation domain of the cda synthetase
Total Genus 141
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
446
structure length
435
Chain Sequence
NSSVRHGLTSAQHEVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords CDA peptide synthetase I
publication title Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
source organism Streptomyces coelicolor
molecule tags Biosynthetic protein
total genus 141
structure length 435
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 4jn5A01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 4jn5A02
1DPCA 5KJVA 2ZBAA 5T3EA 1CLAA 1XL7A 4N72A 1DPBA 1DPDA 1EADA 1QCAA 2IHWA 3L60A 3FP0A 4G0BA 5KJSA 5KJWA 2RKTA 4G22A 1L5AA 3U9BA 2XR7A 5KJTA 1EABA 1XMCA 4JN3A 4CLAA 5KJUA 2I9DA 1XL8A 2BGHA 1PD5A 1EAEA 1SCZA 3MAEA 5DU9A 1Q23A 1XMDA 2II5A 3B30A 4KECA 1C4TA 1NOCB 1EAFA 2E1VA 2E1TA 2II4A 2JGPA 2RKVA 3U9FA 4HVMA 1Q9JA 5FALA 1EACA 2CLAA 2II3A 4KE4A 1E2OA 2E1UA 3CLAA 4JN5A 5DUAA 5FANA 1EAAA 2XHGA 3FOTA 3B2SA 2VSQA 4G2MA 1CIAA
chains in the Genus database with same CATH superfamily
5KJVA 5T3EA 1CLAA 1XL7A 4N72A 1DPBA 3L60A 3FP0A 1XMCA 4CLAA 1S5OA 1XL8A 2FY3A 3MAEA 2FY4A 3B30A 4KECA 1C4TA 1NOCB 4EP9A 2II4A 1T7NA 1Q9JA 2II3A 1E2OA 4JN5A 2DEBA 2XHGA 5DUAA 2ZBAA 1QCAA 4G22A 2RCUA 5KJTA 1EABA 2I9DA 1EAEA 1Q23A 1XMDA 2II5A 4EPHA 1T7QA 2E1TA 4HVMA 4EYWA 5FALA 2CLAA 2E1UA 5FANA 2FYOA 1T7OA 2H3PA 4G2MA 2IHWA 5KJSA 1Q6XA 1L5AA 2XR7A 4JN3A 2H3WA 2H3UA 5KJUA 1NM8A 1PD5A 1SCZA 2FW3A 1EAFA 3U9FA 1T1UA 1EACA 3CLAA 2FY2A 3B2SA 2VSQA 1NDBA 1DPCA 1NDFA 1EADA 1DPDA 4G0BA 5KJWA 2RKTA 3U9BA 2BGHA 2FY5A 5DU9A 2E1VA 2JGPA 2RKVA 4KE4A 2H4TA 1EAAA 1NDIA 3FOTA 1CIAA
chains in the Genus database with same CATH topology
5KJVA 5T3EA 1CLAA 1XL7A 4N72A 1DPBA 3L60A 3FP0A 1XMCA 4CLAA 1S5OA 1XL8A 2FY3A 3MAEA 2FY4A 3B30A 4KECA 1C4TA 1NOCB 4EP9A 2II4A 1T7NA 1Q9JA 2II3A 1E2OA 4JN5A 2DEBA 2XHGA 5DUAA 2ZBAA 1QCAA 4G22A 2RCUA 5KJTA 1EABA 2I9DA 1EAEA 1Q23A 1XMDA 2II5A 4EPHA 1T7QA 2E1TA 4HVMA 4EYWA 5FALA 2CLAA 2E1UA 5FANA 2FYOA 1T7OA 2H3PA 4G2MA 2IHWA 5KJSA 1Q6XA 1L5AA 2XR7A 4JN3A 2H3WA 2H3UA 5KJUA 1NM8A 1PD5A 1SCZA 2FW3A 1EAFA 3U9FA 1T1UA 1EACA 3CLAA 2FY2A 3B2SA 2VSQA 1NDBA 1DPCA 1NDFA 1EADA 1DPDA 4G0BA 5KJWA 2RKTA 3U9BA 2BGHA 2FY5A 5DU9A 2E1VA 2JGPA 2RKVA 4KE4A 2H4TA 1EAAA 1NDIA 3FOTA 1CIAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DPC A;  5KJV A;  2ZBA A;  5T3E A;  1CLA A;  1XL7 A;  4N72 A;  1DPB A;  1DPD A;  1EAD A;  1QCA A;  2IHW A;  3L60 A;  3FP0 A;  4G0B A;  5KJS A;  5KJW A;  2RKT A;  4G22 A;  1L5A A;  3U9B A;  2XR7 A;  5KJT A;  1EAB A;  1XMC A;  4JN3 A;  4CLA A;  5KJU A;  2I9D A;  1XL8 A;  2BGH A;  1PD5 A;  1EAE A;  1SCZ A;  3MAE A;  5DU9 A;  1Q23 A;  1XMD A;  2II5 A;  3B30 A;  4KEC A;  1C4T A;  1NOC B;  1EAF A;  2E1V A;  2E1T A;  2II4 A;  2JGP A;  2RKV A;  3U9F A;  4HVM A;  1Q9J A;  5FAL A;  1EAC A;  2CLA A;  2II3 A;  4KE4 A;  1E2O A;  2E1U A;  3CLA A;  4JN5 A;  5DUA A;  5FAN A;  1EAA A;  2XHG A;  3FOT A;  3B2S A;  2VSQ A;  4G2M A;  1CIA A; 
#chains in the Genus database with same CATH topology
 5KJV A;  5T3E A;  1CLA A;  1XL7 A;  4N72 A;  1DPB A;  3L60 A;  3FP0 A;  1XMC A;  4CLA A;  1S5O A;  1XL8 A;  2FY3 A;  3MAE A;  2FY4 A;  3B30 A;  4KEC A;  1C4T A;  1NOC B;  4EP9 A;  2II4 A;  1T7N A;  1Q9J A;  2II3 A;  1E2O A;  4JN5 A;  2DEB A;  2XHG A;  5DUA A;  2ZBA A;  1QCA A;  4G22 A;  2RCU A;  5KJT A;  1EAB A;  2I9D A;  1EAE A;  1Q23 A;  1XMD A;  2II5 A;  4EPH A;  1T7Q A;  2E1T A;  4HVM A;  4EYW A;  5FAL A;  2CLA A;  2E1U A;  5FAN A;  2FYO A;  1T7O A;  2H3P A;  4G2M A;  2IHW A;  5KJS A;  1Q6X A;  1L5A A;  2XR7 A;  4JN3 A;  2H3W A;  2H3U A;  5KJU A;  1NM8 A;  1PD5 A;  1SCZ A;  2FW3 A;  1EAF A;  3U9F A;  1T1U A;  1EAC A;  3CLA A;  2FY2 A;  3B2S A;  2VSQ A;  1NDB A;  1DPC A;  1NDF A;  1EAD A;  1DPD A;  4G0B A;  5KJW A;  2RKT A;  3U9B A;  2BGH A;  2FY5 A;  5DU9 A;  2E1V A;  2JGP A;  2RKV A;  4KE4 A;  2H4T A;  1EAA A;  1NDI A;  3FOT A;  1CIA A; 
#chains in the Genus database with same CATH homology
 5KJV A;  5T3E A;  1CLA A;  1XL7 A;  4N72 A;  1DPB A;  3L60 A;  3FP0 A;  1XMC A;  4CLA A;  1S5O A;  1XL8 A;  2FY3 A;  3MAE A;  2FY4 A;  3B30 A;  4KEC A;  1C4T A;  1NOC B;  4EP9 A;  2II4 A;  1T7N A;  1Q9J A;  2II3 A;  1E2O A;  4JN5 A;  2DEB A;  2XHG A;  5DUA A;  2ZBA A;  1QCA A;  4G22 A;  2RCU A;  5KJT A;  1EAB A;  2I9D A;  1EAE A;  1Q23 A;  1XMD A;  2II5 A;  4EPH A;  1T7Q A;  2E1T A;  4HVM A;  4EYW A;  5FAL A;  2CLA A;  2E1U A;  5FAN A;  2FYO A;  1T7O A;  2H3P A;  4G2M A;  2IHW A;  5KJS A;  1Q6X A;  1L5A A;  2XR7 A;  4JN3 A;  2H3W A;  2H3U A;  5KJU A;  1NM8 A;  1PD5 A;  1SCZ A;  2FW3 A;  1EAF A;  3U9F A;  1T1U A;  1EAC A;  3CLA A;  2FY2 A;  3B2S A;  2VSQ A;  1NDB A;  1DPC A;  1NDF A;  1EAD A;  1DPD A;  4G0B A;  5KJW A;  2RKT A;  3U9B A;  2BGH A;  2FY5 A;  5DU9 A;  2E1V A;  2JGP A;  2RKV A;  4KE4 A;  2H4T A;  1EAA A;  1NDI A;  3FOT A;  1CIA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...