4JNFA

Allosteric opening of the polypeptide-binding site when an hsp70 binds atp
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
213
structure length
213
Chain Sequence
SVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSMGGAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
pubmed doi rcsb
molecule tags Chaperone
source organism Escherichia coli
molecule keywords Hsp70 CHAPERONE DnaK
total genus 64
structure length 213
sequence length 213
ec nomenclature
pdb deposition date 2013-03-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 4jnfA02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 4jnfA01
4R5KA 4E81A 1DKYA 3L3OM 4EZWA 4F00A 2OP6A 4EZPA 3C7NB 4HYBA 3N8EA 4H6HA 2QXLA 1DG4A 4JNFA 4JN4A 4R5GA 4EZRA 4H6IA 1YUWA 2V7YA 4EZNA 2QFFA 4EZVA 3D2EA 4PO2A 2WINM 4JWEA 4R5IA 3T47A 3T48A 7HSCA 1CKRA 4R5JA 5E84A 4B9QA 3DPQA 2KHOA 4HY9A 4R5LA 3T46A 4JWCA 3T4AG 4EZUA 4F01A 4JWDA 2BPRA 4WV7A 3OHXM 3H0XA 3DPPA 4JNEA 5TKYA 3C7NA 4EZYA 1BPRA 1Q5LA 3D2FA 4EZQA 3DQGA 4EZTA 4FL9A 4JWIA 3DOBA 3DPOA 4EZXA 4WV5A 1U00A 3T49A 4EZZA 4EZOA 4EZSA 1DKXA 3QNJA 1DKZA
chains in the Genus database with same CATH superfamily
2JNKA 4H6HA 3EJUA 4FZSA 2Z8YA 3D4YA 1TQSA 3LVTA 3HAIA 4AZGA 4B9QA 2EFKA 1SU6A 4EZZA 3DDFA 4ILIA 2Q12A 3DDGA 5KBPA 3SOGA 3C7NB 3KAWA 2EWFA 1YUWA 1GN9A 2X5CA 2QKWA 4EZYA 3BUPA 2YIBA 4AZ6A 1QX1A 2YL9A 3ER8C 4ILGA 3CZNA 2Q13A 3I01A 3DX4A 4I1QA 1TQVA 3LMFA 4H8SA 2X3WA 3T48A 4WPEA 2X3XA 3PLTA 2PMRA 2F18A 2EFLA 3CV5A 1O7DB 1MJGA 4FZPA 2GA9D 2YL8A 3QNIA 3A98A 1ZYLA 2V0OA 2Z0NA 5C5BB 4H6IA 3GI7A 3CAZA 4ILHB 3BVUA 3L3PA 2WYHA 4JNEA 1SU8A 1URUA 2YKTA 2RAKA 3DOBA 3D52A 2OP6A 3ACOA 4IWOA 2YL5A 3O3MB 3ZEDA 4E3CA 2N3KA 2OBMA 4ATMA 4KIKB 7HSCA 2WYIA 4FM3A 3ERCC 3OK8A 4EZUA 2BPRA 1R33A 2ND0A 1HTYA 2JNSA 2YIAA 3DPOA 3EJQA 3SYVA 3BVWA 4EZOA 2F1AA 3VKHA 2D4CA 3L3OM 1E1DA 4AZ7A 2ZXQA 4IWQA 2QFFA 3T46A 4JWDA 4NPHA 1OA0A 3D2FA 2RT6A 1TQTA 3DX3A 5TKYA 4E81A 2ELBA 3BUDA 4AZCA 1DG4A 5FLEX 2GAFD 1I4DA 5FIGA 2O0I1 2Z0OA 1E9VA 3Q84A 2OW6A 3BUBA 3LLLA 4FZOA 1GNLA 3B53X 4I43A 1I49A 2ALWA 1I4LA 3UITA 4EZWA 3HAHA 4IM2A 4JN4A 4AZIA 2LM0A 4PO2A 5E84A 4R5LA 1ZWWA 2YI9A 2FYVA 1PS3A 3EJRA 4JL9A 4EZXA 2GF4A 3KDRA 3QNJA 1GNTA 3BVVA 3BVTA 2F7OA 3B51X 4EZVA 4R5IA 3T47A 3DPQA 3CKDA 3SBTB 2FICA 4HR1A 3H0XA 1BPRA 1TQUA 3ER9B 2X3VA 1E2UA 1U00A 3T49A 2YIVX 1I4TA 4JNFA 2D1LA 1LQ7A 1OA1A 3I39X 3D4ZA 1UPXA 3FD9A 2MI7A 3SBSA 2YI8A 4AZ5A 1Q5LA 4UDYX 4M0MA 2RAIA 4NQIA 4AZBA 4DYLA 2Z0VA 4HYBA 1DKZA 2PY6A 4NSWA 4AVMA 4JWEA 2F1BA 3T4AG 2KHOA 4JWCA 4WV7A 3QE6A 4AZCB 3DQGA 2F7QA 3DX1A 4IM3A 3VEBA 3O3NB 3QWEA 4G6QA 4WV5A 1DKXA 3EJSA 4IWPA 3DX2A 1YWMA 4F00A 3N8EA 2C08A 2RAJA 4EZNA 3I2WA 1WDZA 2OBLA 3M3WA 4HY9A 2EX3B 3EJTA 4JLCA 1SU7A 3KAVA 1W9MA 3RV1A 3B52X 2OZNB 2YL6A 4R5GA 2YLAA 3I04A 1R5EA 3D2EA 1X04A 4F01A 3RPMA 3OHXM 3DPPA 3C7NA 4EZQA 1HXKA 2NCZA 1QWNA 2F7RA 2YLLA 1O7DC 1DKYA 4HR1B 4UDXX 4EZPA 4MQDA 3G9GA 3BVXA 4IM0A 3O3OB 2WINM 1CKRA 2OW7A 3F7WA 4EZTA 4D8JA 4BNEA 1TQWA 4R5KA 2F7PA 4DCNC 2OO2A 2QXLA 1R34A 1QWUA 3RV0A 4EZRA 4AZHA 3ABHA 3BLBA 3HAJA 3Q0KA 3DX0A 3CVRA 1HWWA 1OAOA 5C5BA 3CZSA 4FL9A 1X03A 4JWIA 3DYTA 1SUFA 3D50A 4AKVA 3BUQA 1JQKA 2LXYA 3BUIA 4R5JA 3QA8A 2ND1A 1Y2OA 3EJPA 3D51A 3ZEFA 3VEAA 4IW0A 4KIKA 4WPCA 4EZSA 3OWGA 2V7YA
chains in the Genus database with same CATH topology
4IWOA 3KAVA 1GNTA 1W9MA 3RV1A 3B52X 3O3MB 4H6HA 3ZEDA 4E3CA 2N3KA 2Z8YA 4R5GA 2OBMA 3I04A 3B51X 4KIKB 4EZVA 3D2EA 7HSCA 4R5IA 3T47A 4FM3A 3ERCC 4B9QA 3DPQA 4EZUA 4F01A 2BPRA 3SBTB 4HR1A 3OHXM 3H0XA 2ND0A 3DPPA 1BPRA 3C7NA 4EZQA 3ER9B 2JNSA 2NCZA 2YIAA 1SU6A 3DPOA 1E2UA 1U00A 3T49A 4EZZA 4EZOA 4ILIA 2YIVX 3VKHA 4JNFA 1DKYA 4HR1B 3L3OM 1OA1A 4UDXX 3I39X 4EZPA 3C7NB 4MQDA 1E1DA 1UPXA 3KAWA 2EWFA 1YUWA 1GN9A 3FD9A 4IWQA 4IM0A 2QFFA 3O3OB 2WINM 3SBSA 1CKRA 2YI8A 2X5CA 3T46A 3F7WA 4JWDA 4NPHA 1OA0A 4EZYA 1Q5LA 2YIBA 3D2FA 4M0MA 4UDYX 2RT6A 4EZTA 3DOBA 4D8JA 3ER8C 4ILGA 4HYBA 5TKYA 1DKZA 4R5KA 4E81A 3I01A 2QXLA 1DG4A 5FLEX 2GAFD 4EZRA 3RV0A 2PY6A 3LMFA 5FIGA 1E9VA 4JWEA 3T48A 3T4AG 2KHOA 4JWCA 4WV7A 3DQGA 1MJGA 1OAOA 2GA9D 1GNLA 4IM3A 3VEBA 3B53X 4JWIA 4FL9A 3O3NB 4I43A 4G6QA 4WV5A 3A98A 1SUFA 1DKXA 4IWPA 1ZYLA 3UITA 4EZWA 4F00A 4IM2A 3N8EA 1JQKA 4JN4A 4H6IA 3GI7A 4EZNA 2LM0A 4PO2A 4R5JA 5E84A 2OBLA 3QA8A 2ND1A 4HY9A 4R5LA 4ILHB 2EX3B 2YI9A 4JNEA 1SU8A 4JL9A 4JLCA 3ZEFA 4EZXA 3VEAA 4IW0A 4KIKA 1SU7A 4EZSA 3OWGA 2V7YA 3KDRA 3QNJA 2OP6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R5K A;  4E81 A;  1DKY A;  3L3O M;  4EZW A;  4F00 A;  2OP6 A;  4EZP A;  3C7N B;  4HYB A;  3N8E A;  4H6H A;  2QXL A;  1DG4 A;  4JNF A;  4JN4 A;  4R5G A;  4EZR A;  4H6I A;  1YUW A;  2V7Y A;  4EZN A;  2QFF A;  4EZV A;  3D2E A;  4PO2 A;  2WIN M;  4JWE A;  4R5I A;  3T47 A;  3T48 A;  7HSC A;  1CKR A;  4R5J A;  5E84 A;  4B9Q A;  3DPQ A;  2KHO A;  4HY9 A;  4R5L A;  3T46 A;  4JWC A;  3T4A G;  4EZU A;  4F01 A;  4JWD A;  2BPR A;  4WV7 A;  3OHX M;  3H0X A;  3DPP A;  4JNE A;  5TKY A;  3C7N A;  4EZY A;  1BPR A;  1Q5L A;  3D2F A;  4EZQ A;  3DQG A;  4EZT A;  4FL9 A;  4JWI A;  3DOB A;  3DPO A;  4EZX A;  4WV5 A;  1U00 A;  3T49 A;  4EZZ A;  4EZO A;  4EZS A;  1DKX A;  3QNJ A;  1DKZ A; 
#chains in the Genus database with same CATH topology
 2JNK A;  4H6H A;  3EJU A;  4FZS A;  2Z8Y A;  3D4Y A;  1TQS A;  3LVT A;  3HAI A;  4AZG A;  4B9Q A;  2EFK A;  1SU6 A;  4EZZ A;  3DDF A;  4ILI A;  2Q12 A;  3DDG A;  5KBP A;  3SOG A;  3C7N B;  3KAW A;  2EWF A;  1YUW A;  1GN9 A;  2X5C A;  2QKW A;  4EZY A;  3BUP A;  2YIB A;  4AZ6 A;  1QX1 A;  2YL9 A;  3ER8 C;  4ILG A;  3CZN A;  2Q13 A;  3I01 A;  3DX4 A;  4I1Q A;  1TQV A;  3LMF A;  4H8S A;  2X3W A;  3T48 A;  4WPE A;  2X3X A;  3PLT A;  2PMR A;  2F18 A;  2EFL A;  3CV5 A;  1O7D B;  1MJG A;  4FZP A;  2GA9 D;  2YL8 A;  3QNI A;  3A98 A;  1ZYL A;  2V0O A;  2Z0N A;  5C5B B;  4H6I A;  3GI7 A;  3CAZ A;  4ILH B;  3BVU A;  3L3P A;  2WYH A;  4JNE A;  1SU8 A;  1URU A;  2YKT A;  2RAK A;  3DOB A;  3D52 A;  2OP6 A;  3ACO A;  4IWO A;  2YL5 A;  3O3M B;  3ZED A;  4E3C A;  2N3K A;  2OBM A;  4ATM A;  4KIK B;  7HSC A;  2WYI A;  4FM3 A;  3ERC C;  3OK8 A;  4EZU A;  2BPR A;  1R33 A;  2ND0 A;  1HTY A;  2JNS A;  2YIA A;  3DPO A;  3EJQ A;  3SYV A;  3BVW A;  4EZO A;  2F1A A;  3VKH A;  2D4C A;  3L3O M;  1E1D A;  4AZ7 A;  2ZXQ A;  4IWQ A;  2QFF A;  3T46 A;  4JWD A;  4NPH A;  1OA0 A;  3D2F A;  2RT6 A;  1TQT A;  3DX3 A;  5TKY A;  4E81 A;  2ELB A;  3BUD A;  4AZC A;  1DG4 A;  5FLE X;  2GAF D;  1I4D A;  5FIG A;  2O0I 1;  2Z0O A;  1E9V A;  3Q84 A;  2OW6 A;  3BUB A;  3LLL A;  4FZO A;  1GNL A;  3B53 X;  4I43 A;  1I49 A;  2ALW A;  1I4L A;  3UIT A;  4EZW A;  3HAH A;  4IM2 A;  4JN4 A;  4AZI A;  2LM0 A;  4PO2 A;  5E84 A;  4R5L A;  1ZWW A;  2YI9 A;  2FYV A;  1PS3 A;  3EJR A;  4JL9 A;  4EZX A;  2GF4 A;  3KDR A;  3QNJ A;  1GNT A;  3BVV A;  3BVT A;  2F7O A;  3B51 X;  4EZV A;  4R5I A;  3T47 A;  3DPQ A;  3CKD A;  3SBT B;  2FIC A;  4HR1 A;  3H0X A;  1BPR A;  1TQU A;  3ER9 B;  2X3V A;  1E2U A;  1U00 A;  3T49 A;  2YIV X;  1I4T A;  4JNF A;  2D1L A;  1LQ7 A;  1OA1 A;  3I39 X;  3D4Z A;  1UPX A;  3FD9 A;  2MI7 A;  3SBS A;  2YI8 A;  4AZ5 A;  1Q5L A;  4UDY X;  4M0M A;  2RAI A;  4NQI A;  4AZB A;  4DYL A;  2Z0V A;  4HYB A;  1DKZ A;  2PY6 A;  4NSW A;  4AVM A;  4JWE A;  2F1B A;  3T4A G;  2KHO A;  4JWC A;  4WV7 A;  3QE6 A;  4AZC B;  3DQG A;  2F7Q A;  3DX1 A;  4IM3 A;  3VEB A;  3O3N B;  3QWE A;  4G6Q A;  4WV5 A;  1DKX A;  3EJS A;  4IWP A;  3DX2 A;  1YWM A;  4F00 A;  3N8E A;  2C08 A;  2RAJ A;  4EZN A;  3I2W A;  1WDZ A;  2OBL A;  3M3W A;  4HY9 A;  2EX3 B;  3EJT A;  4JLC A;  1SU7 A;  3KAV A;  1W9M A;  3RV1 A;  3B52 X;  2OZN B;  2YL6 A;  4R5G A;  2YLA A;  3I04 A;  1R5E A;  3D2E A;  1X04 A;  4F01 A;  3RPM A;  3OHX M;  3DPP A;  3C7N A;  4EZQ A;  1HXK A;  2NCZ A;  1QWN A;  2F7R A;  2YLL A;  1O7D C;  1DKY A;  4HR1 B;  4UDX X;  4EZP A;  4MQD A;  3G9G A;  3BVX A;  4IM0 A;  3O3O B;  2WIN M;  1CKR A;  2OW7 A;  3F7W A;  4EZT A;  4D8J A;  4BNE A;  1TQW A;  4R5K A;  2F7P A;  4DCN C;  2OO2 A;  2QXL A;  1R34 A;  1QWU A;  3RV0 A;  4EZR A;  4AZH A;  3ABH A;  3BLB A;  3HAJ A;  3Q0K A;  3DX0 A;  3CVR A;  1HWW A;  1OAO A;  5C5B A;  3CZS A;  4FL9 A;  1X03 A;  4JWI A;  3DYT A;  1SUF A;  3D50 A;  4AKV A;  3BUQ A;  1JQK A;  2LXY A;  3BUI A;  4R5J A;  3QA8 A;  2ND1 A;  1Y2O A;  3EJP A;  3D51 A;  3ZEF A;  3VEA A;  4IW0 A;  4KIK A;  4WPC A;  4EZS A;  3OWG A;  2V7Y A; 
#chains in the Genus database with same CATH homology
 4IWO A;  3KAV A;  1GNT A;  1W9M A;  3RV1 A;  3B52 X;  3O3M B;  4H6H A;  3ZED A;  4E3C A;  2N3K A;  2Z8Y A;  4R5G A;  2OBM A;  3I04 A;  3B51 X;  4KIK B;  4EZV A;  3D2E A;  7HSC A;  4R5I A;  3T47 A;  4FM3 A;  3ERC C;  4B9Q A;  3DPQ A;  4EZU A;  4F01 A;  2BPR A;  3SBT B;  4HR1 A;  3OHX M;  3H0X A;  2ND0 A;  3DPP A;  1BPR A;  3C7N A;  4EZQ A;  3ER9 B;  2JNS A;  2NCZ A;  2YIA A;  1SU6 A;  3DPO A;  1E2U A;  1U00 A;  3T49 A;  4EZZ A;  4EZO A;  4ILI A;  2YIV X;  3VKH A;  4JNF A;  1DKY A;  4HR1 B;  3L3O M;  1OA1 A;  4UDX X;  3I39 X;  4EZP A;  3C7N B;  4MQD A;  1E1D A;  1UPX A;  3KAW A;  2EWF A;  1YUW A;  1GN9 A;  3FD9 A;  4IWQ A;  4IM0 A;  2QFF A;  3O3O B;  2WIN M;  3SBS A;  1CKR A;  2YI8 A;  2X5C A;  3T46 A;  3F7W A;  4JWD A;  4NPH A;  1OA0 A;  4EZY A;  1Q5L A;  2YIB A;  3D2F A;  4M0M A;  4UDY X;  2RT6 A;  4EZT A;  3DOB A;  4D8J A;  3ER8 C;  4ILG A;  4HYB A;  5TKY A;  1DKZ A;  4R5K A;  4E81 A;  3I01 A;  2QXL A;  1DG4 A;  5FLE X;  2GAF D;  4EZR A;  3RV0 A;  2PY6 A;  3LMF A;  5FIG A;  1E9V A;  4JWE A;  3T48 A;  3T4A G;  2KHO A;  4JWC A;  4WV7 A;  3DQG A;  1MJG A;  1OAO A;  2GA9 D;  1GNL A;  4IM3 A;  3VEB A;  3B53 X;  4JWI A;  4FL9 A;  3O3N B;  4I43 A;  4G6Q A;  4WV5 A;  3A98 A;  1SUF A;  1DKX A;  4IWP A;  1ZYL A;  3UIT A;  4EZW A;  4F00 A;  4IM2 A;  3N8E A;  1JQK A;  4JN4 A;  4H6I A;  3GI7 A;  4EZN A;  2LM0 A;  4PO2 A;  4R5J A;  5E84 A;  2OBL A;  3QA8 A;  2ND1 A;  4HY9 A;  4R5L A;  4ILH B;  2EX3 B;  2YI9 A;  4JNE A;  1SU8 A;  4JL9 A;  4JLC A;  3ZEF A;  4EZX A;  3VEA A;  4IW0 A;  4KIK A;  1SU7 A;  4EZS A;  3OWG A;  2V7Y A;  3KDR A;  3QNJ A;  2OP6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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