4JRAC

Crystal structure of the botulinum neurotoxin a receptor-binding domain in complex with the luminal domain of sv2c
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
85
structure length
83
Chain Sequence
b'ANFTITMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFF'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Botulinum neurotoxin type A
publication title Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.
pubmed doi rcsb
source organism Clostridium botulinum
molecule tags Hydrolase
total genus 20
structure length 83
sequence length 85
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF13599 Pentapeptide_4 Pentapeptide repeats (9 copies)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.100 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 4jraC00
2J8IA 2F3LA 4JRAC 2BM4A 2G0YA 2BM5A 5JLVC 2BM6A 3N90A 5JMCB 2BM7A 2W7ZA
chains in the Genus database with same CATH superfamily
3UW0A 4Z06A 1DABA 1TYWA 3EQNA 3LMWA 1OGOX 3TH0A 1K8FA 3B4NA 5C1CA 3GQ9A 4XLFA 3JX8A 3EQOA 3GQAA 4W8TA 3GRHA 4OJOA 1KCDA 2VBMA 1BHEA 1NHCA 4XR6A 2VBKA 1EZGA 2BX6A 2PYHA 2W7ZA 1TYXA 1QRBA 1EA0A 1QRCA 1OFEA 2NT9A 3BH6B 2NTPA 4OJ6A 4XKWA 3B8YA 4XKVA 1KTWA 1O8LA 1O88A 2X85A 4OJ5A 1QA3A 3PSSA 3KRGA 1TYUA 4XMYA 4NK8A 4YDTA 1K4ZA 2NSPA 4C2LA 3N6ZA 3PETA 2EWEA 2VFPA 3SYJA 4XM3A 1XG2A 1TSPA 1QA2A 1BN8A 1O8HA 2X6YA 3SUCA 4MR0A 2Z8GA 4OZZA 2VJIA 4NK6A 2VJJA 4YZXA 1GQ8A 1OFMA 4HWVA 2QYUA 3NAWA 4OJLA 1QQ1A 4U4BA 1AIRA 1JTAA 1IDJA 4I84A 1O8KA 1CZFA 1RMGA 4YEIA 2NT6A 1O8JA 2XC1A 2O0WA 3GQ7A 2X6XA 1DBOA 4XLAA 4YCQA 1H80A 5JMCB 4XONA 4XLEA 4YEJA 4XN3A 4XOPA 3VMVA 1VBLA 1O8GA 2VFNA 3FY3A 4XL9A 2IQ7A 2V5IA 4U49A 3SY2A 2UVEA 1RWRA 2QXZA 2O0VA 1DBGA 4OM9A 1O8FA 1PLUA 1RU4A 2J8KA 3ML3A 4YZQA 2X6WA 5JLVC 2NTBA 2O1DA 1IB4A 2VBEA 2PYGA 4MXNA 2BM7A 2XT4A 2BSPA 3VMWA 1QCXA 1PE9A 3AK5A 1O8MA 4W8RA 4XQFA 1JRGA 2VFMA 3SQVA 3SZEA 4OZYA 2J8IA 5DNSA 3LYCA 1IA5A 2QX3A 2BM5A 1HF2A 4Z05A 3B90A 2NTQA 2O17A 3JURA 4W8SA 4XLHA 4XN0A 1K5CA 1QJVA 1OFLA 4XORA 4YZAA 1LLZA 1OGMX 2B0RA 2QY1A 2XTXA 5C1EA 3N90A 4OPWA 1O8EA 1LM1A 2F3LA 4YELA 2PECA 4EW9A 2O6WA 1L1IA 1EE6A 2VFQA 2XTYA 2UVFA 1KCCA 4XNFA 3ZPPA 4YFOA 4YC5A 1O8DA 4XLCA 1O8IA 3P4GA 5AMVA 2BM6A 2XTWA 3T9GA 2INVA 2X3HA 4V02C 3BH7B 3RIQA 2XT2A 3VSTA 4AVZA 2YUHA 2G0YA 1QA1A 3ZSCA 1PXZA 2VFOA 4Z03A 4KH3A 3VSVA 4YZ0A 3WWGA 3H09A 4XOTA 1CLWA 2NSTA 3LJYA 1X0CA 2INUA 1OFDA 1WXRA 1KQ5A 3DU1X 2QZAA 4W8QA 1IDKA 2NZMA 1TYVA 1OOCA 4JRAC 2BM4A 4URRA 1LLWA 1HG8A 3PSZA 3VSUA 4OJPA 2ODLA 1WMRA 2O04A 3GQ8A 2IOUG 3NB2A 4PMHA
chains in the Genus database with same CATH topology
3AK5A 1DABA 1TYWA 3TH0A 1K8FA 3P4GA 4OJLA 1QQ1A 2BM6A 2VFMA 3SZEA 3JX8A 4V02C 2J8IA 3BH7B 3RIQA 3LYCA 2YUHA 2G0YA 4OJOA 2XC1A 1QA1A 2BM5A 1HF2A 2VFOA 4KH3A 2BX6A 5JMCB 2W7ZA 1TYXA 1QRBA 3H09A 1QRCA 3BH6B 1CLWA 3LJYA 4OJ6A 2B0RA 1WXRA 2VFNA 4OJ5A 1KQ5A 3N90A 2V5IA 1QA3A 4OPWA 1TYUA 1K4ZA 1TYVA 2F3LA 4JRAC 3N6ZA 2BM4A 3ML3A 3PETA 4OM9A 2VFQA 2VFPA 3SYJA 5JLVC 4OJPA 1TSPA 1QA2A 2IOUG 2BM7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J8I A;  2F3L A;  4JRA C;  2BM4 A;  2G0Y A;  2BM5 A;  5JLV C;  2BM6 A;  3N90 A;  5JMC B;  2BM7 A;  2W7Z A; 
#chains in the Genus database with same CATH topology
 3UW0 A;  4Z06 A;  1DAB A;  1TYW A;  3EQN A;  3LMW A;  1OGO X;  3TH0 A;  1K8F A;  3B4N A;  5C1C A;  3GQ9 A;  4XLF A;  3JX8 A;  3EQO A;  3GQA A;  4W8T A;  3GRH A;  4OJO A;  1KCD A;  2VBM A;  1BHE A;  1NHC A;  4XR6 A;  2VBK A;  1EZG A;  2BX6 A;  2PYH A;  2W7Z A;  1TYX A;  1QRB A;  1EA0 A;  1QRC A;  1OFE A;  2NT9 A;  3BH6 B;  2NTP A;  4OJ6 A;  4XKW A;  3B8Y A;  4XKV A;  1KTW A;  1O8L A;  1O88 A;  2X85 A;  4OJ5 A;  1QA3 A;  3PSS A;  3KRG A;  1TYU A;  4XMY A;  4NK8 A;  4YDT A;  1K4Z A;  2NSP A;  4C2L A;  3N6Z A;  3PET A;  2EWE A;  2VFP A;  3SYJ A;  4XM3 A;  1XG2 A;  1TSP A;  1QA2 A;  1BN8 A;  1O8H A;  2X6Y A;  3SUC A;  4MR0 A;  2Z8G A;  4OZZ A;  2VJI A;  4NK6 A;  2VJJ A;  4YZX A;  1GQ8 A;  1OFM A;  4HWV A;  2QYU A;  3NAW A;  4OJL A;  1QQ1 A;  4U4B A;  1AIR A;  1JTA A;  1IDJ A;  4I84 A;  1O8K A;  1CZF A;  1RMG A;  4YEI A;  2NT6 A;  1O8J A;  2XC1 A;  2O0W A;  3GQ7 A;  2X6X A;  1DBO A;  4XLA A;  4YCQ A;  1H80 A;  5JMC B;  4XON A;  4XLE A;  4YEJ A;  4XN3 A;  4XOP A;  3VMV A;  1VBL A;  1O8G A;  2VFN A;  3FY3 A;  4XL9 A;  2IQ7 A;  2V5I A;  4U49 A;  3SY2 A;  2UVE A;  1RWR A;  2QXZ A;  2O0V A;  1DBG A;  4OM9 A;  1O8F A;  1PLU A;  1RU4 A;  2J8K A;  3ML3 A;  4YZQ A;  2X6W A;  5JLV C;  2NTB A;  2O1D A;  1IB4 A;  2VBE A;  2PYG A;  4MXN A;  2BM7 A;  2XT4 A;  2BSP A;  3VMW A;  1QCX A;  1PE9 A;  3AK5 A;  1O8M A;  4W8R A;  4XQF A;  1JRG A;  2VFM A;  3SQV A;  3SZE A;  4OZY A;  2J8I A;  5DNS A;  3LYC A;  1IA5 A;  2QX3 A;  2BM5 A;  1HF2 A;  4Z05 A;  3B90 A;  2NTQ A;  2O17 A;  3JUR A;  4W8S A;  4XLH A;  4XN0 A;  1K5C A;  1QJV A;  1OFL A;  4XOR A;  4YZA A;  1LLZ A;  1OGM X;  2B0R A;  2QY1 A;  2XTX A;  5C1E A;  3N90 A;  4OPW A;  1O8E A;  1LM1 A;  2F3L A;  4YEL A;  2PEC A;  4EW9 A;  2O6W A;  1L1I A;  1EE6 A;  2VFQ A;  2XTY A;  2UVF A;  1KCC A;  4XNF A;  3ZPP A;  4YFO A;  4YC5 A;  1O8D A;  4XLC A;  1O8I A;  3P4G A;  5AMV A;  2BM6 A;  2XTW A;  3T9G A;  2INV A;  2X3H A;  4V02 C;  3BH7 B;  3RIQ A;  2XT2 A;  3VST A;  4AVZ A;  2YUH A;  2G0Y A;  1QA1 A;  3ZSC A;  1PXZ A;  2VFO A;  4Z03 A;  4KH3 A;  3VSV A;  4YZ0 A;  3WWG A;  3H09 A;  4XOT A;  1CLW A;  2NST A;  3LJY A;  1X0C A;  2INU A;  1OFD A;  1WXR A;  1KQ5 A;  3DU1 X;  2QZA A;  4W8Q A;  1IDK A;  2NZM A;  1TYV A;  1OOC A;  4JRA C;  2BM4 A;  4URR A;  1LLW A;  1HG8 A;  3PSZ A;  3VSU A;  4OJP A;  2ODL A;  1WMR A;  2O04 A;  3GQ8 A;  2IOU G;  3NB2 A;  4PMH A; 
#chains in the Genus database with same CATH homology
 3AK5 A;  1DAB A;  1TYW A;  3TH0 A;  1K8F A;  3P4G A;  4OJL A;  1QQ1 A;  2BM6 A;  2VFM A;  3SZE A;  3JX8 A;  4V02 C;  2J8I A;  3BH7 B;  3RIQ A;  3LYC A;  2YUH A;  2G0Y A;  4OJO A;  2XC1 A;  1QA1 A;  2BM5 A;  1HF2 A;  2VFO A;  4KH3 A;  2BX6 A;  5JMC B;  2W7Z A;  1TYX A;  1QRB A;  3H09 A;  1QRC A;  3BH6 B;  1CLW A;  3LJY A;  4OJ6 A;  2B0R A;  1WXR A;  2VFN A;  4OJ5 A;  1KQ5 A;  3N90 A;  2V5I A;  1QA3 A;  4OPW A;  1TYU A;  1K4Z A;  1TYV A;  2F3L A;  4JRA C;  3N6Z A;  2BM4 A;  3ML3 A;  3PET A;  4OM9 A;  2VFQ A;  2VFP A;  3SYJ A;  5JLV C;  4OJP A;  1TSP A;  1QA2 A;  2IOU G;  2BM7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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