4K47A

Structure of the streptococcus pneumoniae leucyl-trna synthetase editing domain bound to a benzoxaborole-amp adduct
Total Genus 52
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
183
structure length
183
Chain Sequence
TGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVASLEEKGCGQEKV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Ligase/ligase inhibitor
molecule keywords Leucine--tRNA ligase
total genus 52
structure length 183
sequence length 183
ec nomenclature ec 6.1.1.4: Leucine--tRNA ligase.
pdb deposition date 2013-04-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 4k47A00
1JZQA 4ARIA 1WKBA 2AJHA 4AS1A 4CQNA 3ZJTA 1FFYA 2WFGA 4K48A 1WNYA 2BTEA 1OBHA 1UDZA 4AQ7A 1WZ2A 3ZJVA 5AGJA 5AGTA 1UE0A 1IVSA 2WFDA 2WFEA 4ARCA 3PZ6A 2V0CA 5AGIA 1QU2A 2AJIA 1OBCA 1WK8A 3ZJUA 1WK9A 1QU3A 1GAXA 1WKAA 1ILEA 2V0GA 4K47A 2BYTA 3O0AA 1JZSA 5AGRA 3ZGZA 1WNZA 3PZ5A 2AJGA 1H3NA 3PZ0A 5AGHA 5AGSA
chains in the Genus database with same CATH superfamily
1JZQA 4ARIA 1WKBA 2AJHA 4AS1A 4CQNA 3ZJTA 1FFYA 2WFGA 4K48A 1WNYA 2BTEA 1OBHA 1UDZA 4AQ7A 1WZ2A 3ZJVA 5AGJA 5AGTA 1UE0A 1IVSA 2WFDA 2WFEA 4ARCA 3PZ6A 2V0CA 5AGIA 1QU2A 2AJIA 1OBCA 1WK8A 3ZJUA 1WK9A 1QU3A 1GAXA 1WKAA 1ILEA 2V0GA 4K47A 2BYTA 3O0AA 1JZSA 5AGRA 3ZGZA 1WNZA 3PZ5A 2AJGA 1H3NA 3PZ0A 5AGHA 5AGSA
chains in the Genus database with same CATH topology
1JZQA 4ARIA 1WKBA 2AJHA 4AS1A 4CQNA 3ZJTA 1FFYA 2WFGA 4K48A 1WNYA 2BTEA 1OBHA 1UDZA 4AQ7A 1WZ2A 3ZJVA 5AGJA 5AGTA 1UE0A 1IVSA 2WFDA 2WFEA 4ARCA 3PZ6A 2V0CA 5AGIA 1QU2A 2AJIA 1OBCA 1WK8A 3ZJUA 1WK9A 1QU3A 1GAXA 1WKAA 1ILEA 2V0GA 4K47A 2BYTA 3O0AA 1JZSA 5AGRA 3ZGZA 1WNZA 3PZ5A 2AJGA 1H3NA 3PZ0A 5AGHA 5AGSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JZQ A;  4ARI A;  1WKB A;  2AJH A;  4AS1 A;  4CQN A;  3ZJT A;  1FFY A;  2WFG A;  4K48 A;  1WNY A;  2BTE A;  1OBH A;  1UDZ A;  4AQ7 A;  1WZ2 A;  3ZJV A;  5AGJ A;  5AGT A;  1UE0 A;  1IVS A;  2WFD A;  2WFE A;  4ARC A;  3PZ6 A;  2V0C A;  5AGI A;  1QU2 A;  2AJI A;  1OBC A;  1WK8 A;  3ZJU A;  1WK9 A;  1QU3 A;  1GAX A;  1WKA A;  1ILE A;  2V0G A;  4K47 A;  2BYT A;  3O0A A;  1JZS A;  5AGR A;  3ZGZ A;  1WNZ A;  3PZ5 A;  2AJG A;  1H3N A;  3PZ0 A;  5AGH A;  5AGS A; 
#chains in the Genus database with same CATH topology
 1JZQ A;  4ARI A;  1WKB A;  2AJH A;  4AS1 A;  4CQN A;  3ZJT A;  1FFY A;  2WFG A;  4K48 A;  1WNY A;  2BTE A;  1OBH A;  1UDZ A;  4AQ7 A;  1WZ2 A;  3ZJV A;  5AGJ A;  5AGT A;  1UE0 A;  1IVS A;  2WFD A;  2WFE A;  4ARC A;  3PZ6 A;  2V0C A;  5AGI A;  1QU2 A;  2AJI A;  1OBC A;  1WK8 A;  3ZJU A;  1WK9 A;  1QU3 A;  1GAX A;  1WKA A;  1ILE A;  2V0G A;  4K47 A;  2BYT A;  3O0A A;  1JZS A;  5AGR A;  3ZGZ A;  1WNZ A;  3PZ5 A;  2AJG A;  1H3N A;  3PZ0 A;  5AGH A;  5AGS A; 
#chains in the Genus database with same CATH homology
 1JZQ A;  4ARI A;  1WKB A;  2AJH A;  4AS1 A;  4CQN A;  3ZJT A;  1FFY A;  2WFG A;  4K48 A;  1WNY A;  2BTE A;  1OBH A;  1UDZ A;  4AQ7 A;  1WZ2 A;  3ZJV A;  5AGJ A;  5AGT A;  1UE0 A;  1IVS A;  2WFD A;  2WFE A;  4ARC A;  3PZ6 A;  2V0C A;  5AGI A;  1QU2 A;  2AJI A;  1OBC A;  1WK8 A;  3ZJU A;  1WK9 A;  1QU3 A;  1GAX A;  1WKA A;  1ILE A;  2V0G A;  4K47 A;  2BYT A;  3O0A A;  1JZS A;  5AGR A;  3ZGZ A;  1WNZ A;  3PZ5 A;  2AJG A;  1H3N A;  3PZ0 A;  5AGH A;  5AGS A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...