4K6TA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0385
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
186
structure length
186
Chain Sequence
KYDTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber protein
total genus 44
structure length 186
sequence length 186
chains with identical sequence B, C, E, F, G
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6tA00
4LIYA 4ZDGA 2J12A 1KACA 2WGTA 3CNCA 2QLKA 4XL8A 4ATZA 3QNDA 1UXAA 2WGUA 3EXVA 1QIUA 2O39A 4K6VA 2WBVA 4K6UA 2BZVA 1UXBA 2J1KC 2BZUA 1P69A 3N0IA 1H7ZA 1QHVA 3BQ4A 4XQBA 1KNBA 4XQAA 4K6WA 3O8EA 2WBWA 3L89A 1P6AA 1UXEA 3EXWA 2WSTA 3L88A 2J2JA 1NOBA 2W9LC 4WYJA 3F0YA 4K6TA
chains in the Genus database with same CATH superfamily
3ZPFA 4LIYA 4ZDGA 4XC5A 2J12A 1KACA 2WGTA 3CNCA 2QLKA 4XL8A 3ZPEA 4ATZA 3QNDA 3S6XA 2OJ5A 1UXAA 2WGUA 3EXVA 4D63A 4D62A 1QIUA 2IUNA 2O39A 2BT8A 4K6VA 2VTWA 2WBVA 4K6UA 2BZVA 1KKEA 1UXBA 2J1KC 2BZUA 1P69A 3N0IA 1H7ZA 1QHVA 3BQ4A 2BT7A 4XQBA 1KNBA 4XQAA 4K6WA 3O8EA 2WBWA 2VRSA 4ODBA 5MHSA 3L89A 1P6AA 1UXEA 2BSFA 4GU3A 4CW8A 3EOYA 3EXWA 2OJ6A 2WSTA 3L88A 2J2JA 4GU4A 1NOBA 2W9LC 2JJLA 2IUMA 4WYJA 3F0YA 4K6TA
chains in the Genus database with same CATH topology
4LIYA 4ZDGA 2J12A 1KACA 2WGTA 3CNCA 2QLKA 4XL8A 4ATZA 3QNDA 1UXAA 2WGUA 3EXVA 1QIUA 2O39A 4K6VA 2WBVA 4K6UA 2BZVA 1UXBA 2J1KC 2BZUA 1P69A 3N0IA 1H7ZA 1QHVA 3BQ4A 4XQBA 1KNBA 4XQAA 4K6WA 3O8EA 2WBWA 3L89A 1P6AA 1UXEA 3EXWA 2WSTA 3L88A 2J2JA 1NOBA 2W9LC 4WYJA 3F0YA 4K6TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LIY A;  4ZDG A;  2J12 A;  1KAC A;  2WGT A;  3CNC A;  2QLK A;  4XL8 A;  4ATZ A;  3QND A;  1UXA A;  2WGU A;  3EXV A;  1QIU A;  2O39 A;  4K6V A;  2WBV A;  4K6U A;  2BZV A;  1UXB A;  2J1K C;  2BZU A;  1P69 A;  3N0I A;  1H7Z A;  1QHV A;  3BQ4 A;  4XQB A;  1KNB A;  4XQA A;  4K6W A;  3O8E A;  2WBW A;  3L89 A;  1P6A A;  1UXE A;  3EXW A;  2WST A;  3L88 A;  2J2J A;  1NOB A;  2W9L C;  4WYJ A;  3F0Y A;  4K6T A; 
#chains in the Genus database with same CATH topology
 3ZPF A;  4LIY A;  4ZDG A;  4XC5 A;  2J12 A;  1KAC A;  2WGT A;  3CNC A;  2QLK A;  4XL8 A;  3ZPE A;  4ATZ A;  3QND A;  3S6X A;  2OJ5 A;  1UXA A;  2WGU A;  3EXV A;  4D63 A;  4D62 A;  1QIU A;  2IUN A;  2O39 A;  2BT8 A;  4K6V A;  2VTW A;  2WBV A;  4K6U A;  2BZV A;  1KKE A;  1UXB A;  2J1K C;  2BZU A;  1P69 A;  3N0I A;  1H7Z A;  1QHV A;  3BQ4 A;  2BT7 A;  4XQB A;  1KNB A;  4XQA A;  4K6W A;  3O8E A;  2WBW A;  2VRS A;  4ODB A;  5MHS A;  3L89 A;  1P6A A;  1UXE A;  2BSF A;  4GU3 A;  4CW8 A;  3EOY A;  3EXW A;  2OJ6 A;  2WST A;  3L88 A;  2J2J A;  4GU4 A;  1NOB A;  2W9L C;  2JJL A;  2IUM A;  4WYJ A;  3F0Y A;  4K6T A; 
#chains in the Genus database with same CATH homology
 4LIY A;  4ZDG A;  2J12 A;  1KAC A;  2WGT A;  3CNC A;  2QLK A;  4XL8 A;  4ATZ A;  3QND A;  1UXA A;  2WGU A;  3EXV A;  1QIU A;  2O39 A;  4K6V A;  2WBV A;  4K6U A;  2BZV A;  1UXB A;  2J1K C;  2BZU A;  1P69 A;  3N0I A;  1H7Z A;  1QHV A;  3BQ4 A;  4XQB A;  1KNB A;  4XQA A;  4K6W A;  3O8E A;  2WBW A;  3L89 A;  1P6A A;  1UXE A;  3EXW A;  2WST A;  3L88 A;  2J2J A;  1NOB A;  2W9L C;  4WYJ A;  3F0Y A;  4K6T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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