4K6VA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0407
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
184
structure length
184
Chain Sequence
DTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber protein
total genus 45
structure length 184
sequence length 184
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6vA00
4WYJA 3F0YA 2WSTA 2J12A 2W9LC 4K6UA 3BQ4A 3EXWA 3N0IA 4K6TA 1QHVA 3CNCA 4K6VA 2WBWA 2QLKA 3L88A 4K6WA 1KACA 4LIYA 1P6AA 1NOBA 1P69A 2J1KC 2O39A 1UXBA 1KNBA 2WGTA 4XQBA 1UXEA 3L89A 4ZDGA 4XQAA 2BZUA 1QIUA 1UXAA 3EXVA 3QNDA 2BZVA 2J2JA 4XL8A 4ATZA 2WBVA 3O8EA 1H7ZA 2WGUA
chains in the Genus database with same CATH superfamily
4WYJA 3F0YA 1KKEA 2WSTA 2J12A 2W9LC 4K6UA 4GU4A 3BQ4A 3EXWA 5MHSA 3N0IA 4K6TA 1QHVA 2IUNA 2IUMA 3CNCA 4K6VA 2WBWA 4ODBA 2QLKA 3L88A 2BT8A 2VRSA 4K6WA 1KACA 4LIYA 4XC5A 3ZPEA 1P6AA 1NOBA 1P69A 2J1KC 2O39A 1UXBA 4D63A 1KNBA 2WGTA 2OJ5A 4XQBA 1UXEA 2JJLA 3L89A 4ZDGA 4XQAA 2BZUA 4GU3A 3S6XA 3ZPFA 1QIUA 2BSFA 1UXAA 2VTWA 2OJ6A 3EXVA 3EOYA 2BZVA 2J2JA 3QNDA 4XL8A 4ATZA 2WBVA 3O8EA 4D62A 1H7ZA 2WGUA 2BT7A 4CW8A
chains in the Genus database with same CATH topology
4WYJA 3F0YA 2WSTA 2J12A 2W9LC 4K6UA 3BQ4A 3EXWA 3N0IA 4K6TA 1QHVA 3CNCA 4K6VA 2WBWA 2QLKA 3L88A 4K6WA 1KACA 4LIYA 1P6AA 1NOBA 1P69A 2J1KC 2O39A 1UXBA 1KNBA 2WGTA 4XQBA 1UXEA 3L89A 4ZDGA 4XQAA 2BZUA 1QIUA 1UXAA 3EXVA 3QNDA 2BZVA 2J2JA 4XL8A 4ATZA 2WBVA 3O8EA 1H7ZA 2WGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WYJ A;  3F0Y A;  2WST A;  2J12 A;  2W9L C;  4K6U A;  3BQ4 A;  3EXW A;  3N0I A;  4K6T A;  1QHV A;  3CNC A;  4K6V A;  2WBW A;  2QLK A;  3L88 A;  4K6W A;  1KAC A;  4LIY A;  1P6A A;  1NOB A;  1P69 A;  2J1K C;  2O39 A;  1UXB A;  1KNB A;  2WGT A;  4XQB A;  1UXE A;  3L89 A;  4ZDG A;  4XQA A;  2BZU A;  1QIU A;  1UXA A;  3EXV A;  3QND A;  2BZV A;  2J2J A;  4XL8 A;  4ATZ A;  2WBV A;  3O8E A;  1H7Z A;  2WGU A; 
#chains in the Genus database with same CATH topology
 4WYJ A;  3F0Y A;  1KKE A;  2WST A;  2J12 A;  2W9L C;  4K6U A;  4GU4 A;  3BQ4 A;  3EXW A;  5MHS A;  3N0I A;  4K6T A;  1QHV A;  2IUN A;  2IUM A;  3CNC A;  4K6V A;  2WBW A;  4ODB A;  2QLK A;  3L88 A;  2BT8 A;  2VRS A;  4K6W A;  1KAC A;  4LIY A;  4XC5 A;  3ZPE A;  1P6A A;  1NOB A;  1P69 A;  2J1K C;  2O39 A;  1UXB A;  4D63 A;  1KNB A;  2WGT A;  2OJ5 A;  4XQB A;  1UXE A;  2JJL A;  3L89 A;  4ZDG A;  4XQA A;  2BZU A;  4GU3 A;  3S6X A;  3ZPF A;  1QIU A;  2BSF A;  1UXA A;  2VTW A;  2OJ6 A;  3EXV A;  3EOY A;  2BZV A;  2J2J A;  3QND A;  4XL8 A;  4ATZ A;  2WBV A;  3O8E A;  4D62 A;  1H7Z A;  2WGU A;  2BT7 A;  4CW8 A; 
#chains in the Genus database with same CATH homology
 4WYJ A;  3F0Y A;  2WST A;  2J12 A;  2W9L C;  4K6U A;  3BQ4 A;  3EXW A;  3N0I A;  4K6T A;  1QHV A;  3CNC A;  4K6V A;  2WBW A;  2QLK A;  3L88 A;  4K6W A;  1KAC A;  4LIY A;  1P6A A;  1NOB A;  1P69 A;  2J1K C;  2O39 A;  1UXB A;  1KNB A;  2WGT A;  4XQB A;  1UXE A;  3L89 A;  4ZDG A;  4XQA A;  2BZU A;  1QIU A;  1UXA A;  3EXV A;  3QND A;  2BZV A;  2J2J A;  4XL8 A;  4ATZ A;  2WBV A;  3O8E A;  1H7Z A;  2WGU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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