4K6WA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0408
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
183
structure length
183
Chain Sequence
TRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber protein
total genus 42
structure length 183
sequence length 183
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6wA00
3BQ4A 1UXAA 2BZVA 4WYJA 1P69A 2BZUA 1UXBA 4K6WA 1P6AA 2W9LC 3L89A 1KACA 2WGUA 4K6VA 1QIUA 4K6TA 4XQBA 4K6UA 3O8EA 2O39A 4ATZA 4LIYA 4XQAA 3EXWA 1NOBA 2J1KC 1KNBA 3N0IA 2J2JA 3L88A 2WBWA 1UXEA 2WBVA 3QNDA 2J12A 1QHVA 3CNCA 2QLKA 2WSTA 2WGTA 3F0YA 1H7ZA 3EXVA 4ZDGA 4XL8A
chains in the Genus database with same CATH superfamily
2IUNA 2BT8A 3BQ4A 1UXAA 2BZVA 4WYJA 4CW8A 1P69A 2BZUA 3EOYA 1UXBA 4K6WA 4GU3A 2OJ5A 2IUMA 1P6AA 2JJLA 2W9LC 3L89A 1KACA 2WGUA 4K6VA 1QIUA 4K6TA 2VTWA 3ZPEA 4XQBA 4GU4A 4K6UA 3O8EA 2O39A 4ATZA 4LIYA 4XQAA 3EXWA 5MHSA 1NOBA 2J1KC 1KNBA 3N0IA 4D63A 1KKEA 3S6XA 2BT7A 2BSFA 2J2JA 3L88A 2WBWA 4D62A 3ZPFA 4ODBA 1UXEA 2WBVA 3QNDA 2J12A 1QHVA 3CNCA 2QLKA 2WSTA 2WGTA 2VRSA 3F0YA 1H7ZA 3EXVA 4ZDGA 4XL8A 4XC5A 2OJ6A
chains in the Genus database with same CATH topology
3BQ4A 1UXAA 2BZVA 4WYJA 1P69A 2BZUA 1UXBA 4K6WA 1P6AA 2W9LC 3L89A 1KACA 2WGUA 4K6VA 1QIUA 4K6TA 4XQBA 4K6UA 3O8EA 2O39A 4ATZA 4LIYA 4XQAA 3EXWA 1NOBA 2J1KC 1KNBA 3N0IA 2J2JA 3L88A 2WBWA 1UXEA 2WBVA 3QNDA 2J12A 1QHVA 3CNCA 2QLKA 2WSTA 2WGTA 3F0YA 1H7ZA 3EXVA 4ZDGA 4XL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BQ4 A;  1UXA A;  2BZV A;  4WYJ A;  1P69 A;  2BZU A;  1UXB A;  4K6W A;  1P6A A;  2W9L C;  3L89 A;  1KAC A;  2WGU A;  4K6V A;  1QIU A;  4K6T A;  4XQB A;  4K6U A;  3O8E A;  2O39 A;  4ATZ A;  4LIY A;  4XQA A;  3EXW A;  1NOB A;  2J1K C;  1KNB A;  3N0I A;  2J2J A;  3L88 A;  2WBW A;  1UXE A;  2WBV A;  3QND A;  2J12 A;  1QHV A;  3CNC A;  2QLK A;  2WST A;  2WGT A;  3F0Y A;  1H7Z A;  3EXV A;  4ZDG A;  4XL8 A; 
#chains in the Genus database with same CATH topology
 2IUN A;  2BT8 A;  3BQ4 A;  1UXA A;  2BZV A;  4WYJ A;  4CW8 A;  1P69 A;  2BZU A;  3EOY A;  1UXB A;  4K6W A;  4GU3 A;  2OJ5 A;  2IUM A;  1P6A A;  2JJL A;  2W9L C;  3L89 A;  1KAC A;  2WGU A;  4K6V A;  1QIU A;  4K6T A;  2VTW A;  3ZPE A;  4XQB A;  4GU4 A;  4K6U A;  3O8E A;  2O39 A;  4ATZ A;  4LIY A;  4XQA A;  3EXW A;  5MHS A;  1NOB A;  2J1K C;  1KNB A;  3N0I A;  4D63 A;  1KKE A;  3S6X A;  2BT7 A;  2BSF A;  2J2J A;  3L88 A;  2WBW A;  4D62 A;  3ZPF A;  4ODB A;  1UXE A;  2WBV A;  3QND A;  2J12 A;  1QHV A;  3CNC A;  2QLK A;  2WST A;  2WGT A;  2VRS A;  3F0Y A;  1H7Z A;  3EXV A;  4ZDG A;  4XL8 A;  4XC5 A;  2OJ6 A; 
#chains in the Genus database with same CATH homology
 3BQ4 A;  1UXA A;  2BZV A;  4WYJ A;  1P69 A;  2BZU A;  1UXB A;  4K6W A;  1P6A A;  2W9L C;  3L89 A;  1KAC A;  2WGU A;  4K6V A;  1QIU A;  4K6T A;  4XQB A;  4K6U A;  3O8E A;  2O39 A;  4ATZ A;  4LIY A;  4XQA A;  3EXW A;  1NOB A;  2J1K C;  1KNB A;  3N0I A;  2J2J A;  3L88 A;  2WBW A;  1UXE A;  2WBV A;  3QND A;  2J12 A;  1QHV A;  3CNC A;  2QLK A;  2WST A;  2WGT A;  3F0Y A;  1H7Z A;  3EXV A;  4ZDG A;  4XL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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