4KDLA

Crystal structure of p97/vcp n in complex with otu1 ubxl
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
174
structure length
174
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein/hydrolase
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 53
structure length 174
sequence length 174
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4kdlA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 4kdlA02
1UHEA 1VC3B 1H5NA 2E7ZA 2Y0SA 3QWZA 1DMRA 2JIMA 3HU3A 2VUMA 1Y5IA 1CR5A 2EEOB 3GTOA 2VPYA 2R93A 2B63A 1E18A 1EU1A 3IR6A 2V45A 1KQGA 4CRYG 1E32A 2VPZA 3O5AA 3QQ7A 1TWHA 2WAQA 1PQEA 3GTMA 4QIWA 4DMRA 2JV2A 3GTGA 4AAYA 5FTJA 1WCMA 5EPPA 2PMZA 2R7ZA 2VPXA 3CF2A 1AA6A 1CZ5A 1UHDA 2C45A 1PYQA 4KDLA 1G8JA 4D7ZB 4RV0A 3OUGA 5T5MD 3PLXB 2JIRA 4AZDA 1R27A 1YLEA 2DMRA 4KO8A 5DYGA 3IR7A 4CRZA 1Q16A 5FTLA 5C1BA 3H0GA 1SFOA 2JIQA 1TWAA 4GA5A 1WLFA 5B6CA 3TM7B 2YU9A 3CQZA 5GLFA 1KQFA 1FDIA 2NYAA 1QDNA 5T5ID 1DMSA 1PT1A 1SIWA 3GTKA 3TIWA 1AW8B 1TWGA 2JA7A 1I3QA 2KI8A 2V3VA 5FTMA 1E5VA 1IW7D 4GA6A 2VPWA 3GTPA 1E61A 3HKZA 2E2IA 2YUJA 3QQ8A 2E2HA 5FTKA 1S3SA 5C18A 1TWFA 1FDOA 1PPYA 1PQHA 1ZC1A 1TWCA 1CZ4A 3HU2A 2WB1A 2NVYA 3ML1A 1Y1VA 1H0HA 2IV2X 3GTLA 4KODA 1QCSA 1R9TA 3HU1A 2R92A 3FKIA 5FTNA 2JIPA 4AONB 5DYIA 4CS0A 4KDIA 2NVXA 3GTQA 2PJHB 4KLNA 1Y1WA 1PYUB 1E60A 1I50A 4AYBA 1K83A 2JA5A 1Y4ZA 2NAPA 3QC8A 4AOKB 1PT0A 3IR5A 1TMOA 3DMRA 1G8KA 1OGYA 1R7RA 2JIOA 3GTJA 4C2MA 2JA6A 1PQFA
chains in the Genus database with same CATH superfamily
1UHEA 2G6GA 1VC3B 1H5NA 2GFAA 2E7ZA 2Y0SA 3QWZA 3FPTA 1DMRA 3X2IA 2JIMA 1OA7A 3HU3A 3SUMA 2VUMA 2PI8A 1Y5IA 1CR5A 2A6HD 2EEOB 2VPYA 3GTOA 2R93A 1OA9A 3X2HA 1E18A 1N10A 2B63A 1EU1A 3IR6A 2XDPA 2V45A 1KQGA 4CRYG 1E32A 3X2JA 2VPZA 3O5AA 3QQ7A 1HD5A 1I9GA 2QQSA 1TWHA 2WAQA 1PQEA 3GTMA 4QIWA 2O5JD 2A69D 2PJJA 4DMRA 3GTGA 4AAYA 2JV2A 2LW6A 5FTJA 1WCMA 4FERA 5EPPA 2PMZA 4AVRA 4ARCA 2Q1DX 2R7ZA 5D6YA 2VPXA 3CF2A 4FIBA 1BW4A 1AA6A 1CZ5A 1UHDA 4JP7A 3X2MA 1WC2A 2YVLA 4FFTA 3ZGZA 2C45A 4UC4A 1PYQA 2MM2A 4KDLA 1G8JA 4D7ZB 4ZM7A 4RV0A 3MB5A 4FG4A 3OUGA 5T5MD 3LHDA 5GLXA 4CQNA 3PLXB 2JIRA 4AZDA 3SUKA 1ZYRD 1R27A 2Q19X 1YLEA 2DMRA 4KO8A 3SUJA 2Q1AX 2GAEA 3IR7A 4NOHA 5DYGA 3ZJVA 4CRZA 2AE0X 3FPRA 1Q16A 5FTLA 5ERGB 5C1BA 2BH0A 3H0GA 3X2NA 1SFOA 2KY9A 2JIQA 1TWAA 4GA5A 3ZJTA 2KQAA 1WLFA 5B6CA 3TM7B 2YU9A 3CQZA 5GLFA 4L48A 2ENGA 1KQFA 1FDIA 2NYAA 1QDNA 5D6XA 5H4UA 5T5ID 1DMSA 1PT1A 1SIWA 1YNND 3TIWA 3GTKA 1AW8B 1TWGA 3X2OA 1I3QA 2KI8A 3ENGA 2V3VA 2JA7A 5GLYA 5FTMA 1E5VA 1IW7D 5EQJB 3BQBA 3LGAA 4GA6A 2CW0D 5GM9A 1YNJD 2VPWA 1E61A 3GTPA 2YUJA 3HKZA 2E2IA 3D30A 3QQ8A 2E2HA 2PWYA 2BE5D 3SULA 1O54A 5FTKA 1S3SA 2B25A 5D6WA 2HCZX 2A6ED 5C18A 1TWFA 4AS1A 1FDOA 1PPYA 1PQHA 1ZC1A 3X2LA 5CCXA 4JP6A 4JCWA 1TWCA 4JJOA 1CZ4A 2Q1CX 2WB1A 2NVYA 3HU2A 3ML1A 3ZJUA 1Y1VA 1H0HA 2IV2X 3GTLA 4KODA 3FPUA 1L8FA 1QCSA 1R9TA 5CCBA 3HU1A 3X2KA 2PNWA 1BW3A 2R92A 2A68D 3FKIA 3CZBA 4FG2A 2GF7A 2G5DA 2PICA 5FTNA 4AQ7A 2JIPA 4AONB 2MM0A 5DYIA 5CD1A 3M3GA 1SMYD 4CS0A 3X2PA 4ENGA 4ARIA 4KDIA 2NVXA 3GTQA 2PJHB 4JS7A 4KLNA 1Y1WA 1PYUB 1E60A 1I50A 4AYBA 3X2GA 1K83A 1Y4ZA 2NAPA 3QC8A 2JA5A 4AOKB 1PT0A 1TMOA 3IR5A 3DMRA 1G8KA 1OGYA 1R7RA 2JIOA 3GTJA 2Q18X 4C2MA 2QQRA 2JA6A 1PQFA
chains in the Genus database with same CATH topology
1UHEA 2G6GA 1VC3B 1H5NA 2GFAA 2E7ZA 2Y0SA 3QWZA 3FPTA 1DMRA 2JIMA 3HU3A 2VUMA 2PI8A 1Y5IA 1CR5A 2A6HD 2EEOB 2VPYA 3GTOA 2R93A 2B63A 1E18A 1EU1A 3IR6A 2XDPA 2V45A 1KQGA 4CRYG 1E32A 2VPZA 3O5AA 3QQ7A 1I9GA 2QQSA 1TWHA 2WAQA 1PQEA 3GTMA 4QIWA 2O5JD 2A69D 2PJJA 4DMRA 3GTGA 4AAYA 2JV2A 2LW6A 5FTJA 1WCMA 5EPPA 2PMZA 4ARCA 2Q1DX 2R7ZA 5D6YA 2VPXA 3CF2A 4FIBA 1AA6A 1CZ5A 1UHDA 2YVLA 3ZGZA 2C45A 4UC4A 1PYQA 2MM2A 4KDLA 1G8JA 4D7ZB 4RV0A 3MB5A 3OUGA 5T5MD 3LHDA 4CQNA 3PLXB 2JIRA 4AZDA 1ZYRD 1R27A 2Q19X 1YLEA 2DMRA 4KO8A 3ZJVA 2Q1AX 2GAEA 3IR7A 4NOHA 5DYGA 4CRZA 2AE0X 3FPRA 1Q16A 5FTLA 5ERGB 5C1BA 2KY9A 3H0GA 1SFOA 2JIQA 1TWAA 4GA5A 3ZJTA 1WLFA 5B6CA 3TM7B 2YU9A 3CQZA 5GLFA 5D6XA 1KQFA 1FDIA 2NYAA 1QDNA 5T5ID 1DMSA 1PT1A 1SIWA 1YNND 3TIWA 3GTKA 1AW8B 1TWGA 2JA7A 1I3QA 2KI8A 2V3VA 5FTMA 1E5VA 1IW7D 5EQJB 3BQBA 3LGAA 4GA6A 2CW0D 1YNJD 2VPWA 1E61A 3GTPA 2YUJA 3HKZA 2E2IA 3QQ8A 2E2HA 2PWYA 2BE5D 1O54A 5FTKA 1S3SA 2B25A 5D6WA 2A6ED 5C18A 1TWFA 4AS1A 1FDOA 1PPYA 1PQHA 1ZC1A 5CCXA 1TWCA 1CZ4A 2Q1CX 2WB1A 2NVYA 3HU2A 3ML1A 3ZJUA 1Y1VA 1H0HA 2IV2X 3GTLA 4KODA 3FPUA 1QCSA 1R9TA 5CCBA 3HU1A 2PNWA 2R92A 2A68D 3FKIA 3CZBA 2GF7A 2G5DA 2PICA 5FTNA 4AQ7A 2JIPA 4AONB 2MM0A 5DYIA 5CD1A 1SMYD 4CS0A 4ARIA 4KDIA 2NVXA 3GTQA 2PJHB 4KLNA 1Y1WA 1PYUB 1E60A 1I50A 4AYBA 1K83A 2JA5A 1Y4ZA 2NAPA 3QC8A 4AOKB 1PT0A 1TMOA 3IR5A 3DMRA 1G8KA 1OGYA 1R7RA 2JIOA 3GTJA 2Q18X 4C2MA 2QQRA 2JA6A 1PQFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UHE A;  1VC3 B;  1H5N A;  2E7Z A;  2Y0S A;  3QWZ A;  1DMR A;  2JIM A;  3HU3 A;  2VUM A;  1Y5I A;  1CR5 A;  2EEO B;  3GTO A;  2VPY A;  2R93 A;  2B63 A;  1E18 A;  1EU1 A;  3IR6 A;  2V45 A;  1KQG A;  4CRY G;  1E32 A;  2VPZ A;  3O5A A;  3QQ7 A;  1TWH A;  2WAQ A;  1PQE A;  3GTM A;  4QIW A;  4DMR A;  2JV2 A;  3GTG A;  4AAY A;  5FTJ A;  1WCM A;  5EPP A;  2PMZ A;  2R7Z A;  2VPX A;  3CF2 A;  1AA6 A;  1CZ5 A;  1UHD A;  2C45 A;  1PYQ A;  4KDL A;  1G8J A;  4D7Z B;  4RV0 A;  3OUG A;  5T5M D;  3PLX B;  2JIR A;  4AZD A;  1R27 A;  1YLE A;  2DMR A;  4KO8 A;  5DYG A;  3IR7 A;  4CRZ A;  1Q16 A;  5FTL A;  5C1B A;  3H0G A;  1SFO A;  2JIQ A;  1TWA A;  4GA5 A;  1WLF A;  5B6C A;  3TM7 B;  2YU9 A;  3CQZ A;  5GLF A;  1KQF A;  1FDI A;  2NYA A;  1QDN A;  5T5I D;  1DMS A;  1PT1 A;  1SIW A;  3GTK A;  3TIW A;  1AW8 B;  1TWG A;  2JA7 A;  1I3Q A;  2KI8 A;  2V3V A;  5FTM A;  1E5V A;  1IW7 D;  4GA6 A;  2VPW A;  3GTP A;  1E61 A;  3HKZ A;  2E2I A;  2YUJ A;  3QQ8 A;  2E2H A;  5FTK A;  1S3S A;  5C18 A;  1TWF A;  1FDO A;  1PPY A;  1PQH A;  1ZC1 A;  1TWC A;  1CZ4 A;  3HU2 A;  2WB1 A;  2NVY A;  3ML1 A;  1Y1V A;  1H0H A;  2IV2 X;  3GTL A;  4KOD A;  1QCS A;  1R9T A;  3HU1 A;  2R92 A;  3FKI A;  5FTN A;  2JIP A;  4AON B;  5DYI A;  4CS0 A;  4KDI A;  2NVX A;  3GTQ A;  2PJH B;  4KLN A;  1Y1W A;  1PYU B;  1E60 A;  1I50 A;  4AYB A;  1K83 A;  2JA5 A;  1Y4Z A;  2NAP A;  3QC8 A;  4AOK B;  1PT0 A;  3IR5 A;  1TMO A;  3DMR A;  1G8K A;  1OGY A;  1R7R A;  2JIO A;  3GTJ A;  4C2M A;  2JA6 A;  1PQF A; 
#chains in the Genus database with same CATH topology
 1UHE A;  2G6G A;  1VC3 B;  1H5N A;  2GFA A;  2E7Z A;  2Y0S A;  3QWZ A;  3FPT A;  1DMR A;  3X2I A;  2JIM A;  1OA7 A;  3HU3 A;  3SUM A;  2VUM A;  2PI8 A;  1Y5I A;  1CR5 A;  2A6H D;  2EEO B;  2VPY A;  3GTO A;  2R93 A;  1OA9 A;  3X2H A;  1E18 A;  1N10 A;  2B63 A;  1EU1 A;  3IR6 A;  2XDP A;  2V45 A;  1KQG A;  4CRY G;  1E32 A;  3X2J A;  2VPZ A;  3O5A A;  3QQ7 A;  1HD5 A;  1I9G A;  2QQS A;  1TWH A;  2WAQ A;  1PQE A;  3GTM A;  4QIW A;  2O5J D;  2A69 D;  2PJJ A;  4DMR A;  3GTG A;  4AAY A;  2JV2 A;  2LW6 A;  5FTJ A;  1WCM A;  4FER A;  5EPP A;  2PMZ A;  4AVR A;  4ARC A;  2Q1D X;  2R7Z A;  5D6Y A;  2VPX A;  3CF2 A;  4FIB A;  1BW4 A;  1AA6 A;  1CZ5 A;  1UHD A;  4JP7 A;  3X2M A;  1WC2 A;  2YVL A;  4FFT A;  3ZGZ A;  2C45 A;  4UC4 A;  1PYQ A;  2MM2 A;  4KDL A;  1G8J A;  4D7Z B;  4ZM7 A;  4RV0 A;  3MB5 A;  4FG4 A;  3OUG A;  5T5M D;  3LHD A;  5GLX A;  4CQN A;  3PLX B;  2JIR A;  4AZD A;  3SUK A;  1ZYR D;  1R27 A;  2Q19 X;  1YLE A;  2DMR A;  4KO8 A;  3SUJ A;  2Q1A X;  2GAE A;  3IR7 A;  4NOH A;  5DYG A;  3ZJV A;  4CRZ A;  2AE0 X;  3FPR A;  1Q16 A;  5FTL A;  5ERG B;  5C1B A;  2BH0 A;  3H0G A;  3X2N A;  1SFO A;  2KY9 A;  2JIQ A;  1TWA A;  4GA5 A;  3ZJT A;  2KQA A;  1WLF A;  5B6C A;  3TM7 B;  2YU9 A;  3CQZ A;  5GLF A;  4L48 A;  2ENG A;  1KQF A;  1FDI A;  2NYA A;  1QDN A;  5D6X A;  5H4U A;  5T5I D;  1DMS A;  1PT1 A;  1SIW A;  1YNN D;  3TIW A;  3GTK A;  1AW8 B;  1TWG A;  3X2O A;  1I3Q A;  2KI8 A;  3ENG A;  2V3V A;  2JA7 A;  5GLY A;  5FTM A;  1E5V A;  1IW7 D;  5EQJ B;  3BQB A;  3LGA A;  4GA6 A;  2CW0 D;  5GM9 A;  1YNJ D;  2VPW A;  1E61 A;  3GTP A;  2YUJ A;  3HKZ A;  2E2I A;  3D30 A;  3QQ8 A;  2E2H A;  2PWY A;  2BE5 D;  3SUL A;  1O54 A;  5FTK A;  1S3S A;  2B25 A;  5D6W A;  2HCZ X;  2A6E D;  5C18 A;  1TWF A;  4AS1 A;  1FDO A;  1PPY A;  1PQH A;  1ZC1 A;  3X2L A;  5CCX A;  4JP6 A;  4JCW A;  1TWC A;  4JJO A;  1CZ4 A;  2Q1C X;  2WB1 A;  2NVY A;  3HU2 A;  3ML1 A;  3ZJU A;  1Y1V A;  1H0H A;  2IV2 X;  3GTL A;  4KOD A;  3FPU A;  1L8F A;  1QCS A;  1R9T A;  5CCB A;  3HU1 A;  3X2K A;  2PNW A;  1BW3 A;  2R92 A;  2A68 D;  3FKI A;  3CZB A;  4FG2 A;  2GF7 A;  2G5D A;  2PIC A;  5FTN A;  4AQ7 A;  2JIP A;  4AON B;  2MM0 A;  5DYI A;  5CD1 A;  3M3G A;  1SMY D;  4CS0 A;  3X2P A;  4ENG A;  4ARI A;  4KDI A;  2NVX A;  3GTQ A;  2PJH B;  4JS7 A;  4KLN A;  1Y1W A;  1PYU B;  1E60 A;  1I50 A;  4AYB A;  3X2G A;  1K83 A;  1Y4Z A;  2NAP A;  3QC8 A;  2JA5 A;  4AOK B;  1PT0 A;  1TMO A;  3IR5 A;  3DMR A;  1G8K A;  1OGY A;  1R7R A;  2JIO A;  3GTJ A;  2Q18 X;  4C2M A;  2QQR A;  2JA6 A;  1PQF A; 
#chains in the Genus database with same CATH homology
 1UHE A;  2G6G A;  1VC3 B;  1H5N A;  2GFA A;  2E7Z A;  2Y0S A;  3QWZ A;  3FPT A;  1DMR A;  2JIM A;  3HU3 A;  2VUM A;  2PI8 A;  1Y5I A;  1CR5 A;  2A6H D;  2EEO B;  2VPY A;  3GTO A;  2R93 A;  2B63 A;  1E18 A;  1EU1 A;  3IR6 A;  2XDP A;  2V45 A;  1KQG A;  4CRY G;  1E32 A;  2VPZ A;  3O5A A;  3QQ7 A;  1I9G A;  2QQS A;  1TWH A;  2WAQ A;  1PQE A;  3GTM A;  4QIW A;  2O5J D;  2A69 D;  2PJJ A;  4DMR A;  3GTG A;  4AAY A;  2JV2 A;  2LW6 A;  5FTJ A;  1WCM A;  5EPP A;  2PMZ A;  4ARC A;  2Q1D X;  2R7Z A;  5D6Y A;  2VPX A;  3CF2 A;  4FIB A;  1AA6 A;  1CZ5 A;  1UHD A;  2YVL A;  3ZGZ A;  2C45 A;  4UC4 A;  1PYQ A;  2MM2 A;  4KDL A;  1G8J A;  4D7Z B;  4RV0 A;  3MB5 A;  3OUG A;  5T5M D;  3LHD A;  4CQN A;  3PLX B;  2JIR A;  4AZD A;  1ZYR D;  1R27 A;  2Q19 X;  1YLE A;  2DMR A;  4KO8 A;  3ZJV A;  2Q1A X;  2GAE A;  3IR7 A;  4NOH A;  5DYG A;  4CRZ A;  2AE0 X;  3FPR A;  1Q16 A;  5FTL A;  5ERG B;  5C1B A;  2KY9 A;  3H0G A;  1SFO A;  2JIQ A;  1TWA A;  4GA5 A;  3ZJT A;  1WLF A;  5B6C A;  3TM7 B;  2YU9 A;  3CQZ A;  5GLF A;  5D6X A;  1KQF A;  1FDI A;  2NYA A;  1QDN A;  5T5I D;  1DMS A;  1PT1 A;  1SIW A;  1YNN D;  3TIW A;  3GTK A;  1AW8 B;  1TWG A;  2JA7 A;  1I3Q A;  2KI8 A;  2V3V A;  5FTM A;  1E5V A;  1IW7 D;  5EQJ B;  3BQB A;  3LGA A;  4GA6 A;  2CW0 D;  1YNJ D;  2VPW A;  1E61 A;  3GTP A;  2YUJ A;  3HKZ A;  2E2I A;  3QQ8 A;  2E2H A;  2PWY A;  2BE5 D;  1O54 A;  5FTK A;  1S3S A;  2B25 A;  5D6W A;  2A6E D;  5C18 A;  1TWF A;  4AS1 A;  1FDO A;  1PPY A;  1PQH A;  1ZC1 A;  5CCX A;  1TWC A;  1CZ4 A;  2Q1C X;  2WB1 A;  2NVY A;  3HU2 A;  3ML1 A;  3ZJU A;  1Y1V A;  1H0H A;  2IV2 X;  3GTL A;  4KOD A;  3FPU A;  1QCS A;  1R9T A;  5CCB A;  3HU1 A;  2PNW A;  2R92 A;  2A68 D;  3FKI A;  3CZB A;  2GF7 A;  2G5D A;  2PIC A;  5FTN A;  4AQ7 A;  2JIP A;  4AON B;  2MM0 A;  5DYI A;  5CD1 A;  1SMY D;  4CS0 A;  4ARI A;  4KDI A;  2NVX A;  3GTQ A;  2PJH B;  4KLN A;  1Y1W A;  1PYU B;  1E60 A;  1I50 A;  4AYB A;  1K83 A;  2JA5 A;  1Y4Z A;  2NAP A;  3QC8 A;  4AOK B;  1PT0 A;  1TMO A;  3IR5 A;  3DMR A;  1G8K A;  1OGY A;  1R7R A;  2JIO A;  3GTJ A;  2Q18 X;  4C2M A;  2QQR A;  2JA6 A;  1PQF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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