4KEEA

Crystal structure of cofilin mutant (cof1-158p)
Total Genus 34
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
139
structure length
132
Chain Sequence
GSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEESKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of Cofilin Mutant (cof1-158p)
rcsb
molecule tags Actin binding protein
source organism Saccharomyces cerevisiae
molecule keywords Cofilin
total genus 34
structure length 132
sequence length 139
ec nomenclature
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 4keeA00
1T2LA 1JHWA 1PCXA 1EQYS 1DEJS 1Q8GA 1WFSA 3FFKA 3EGXA 1T3YA 4LIZA 1YVNG 2LXXA 1CFYA 3EGXB 2FF6G 3L50A 2LLFA 1M4JA 3A5NS 1AHQA 2L72A 2FF3A 1C0FS 3CI5G 3A5MS 1NPHA 1SVRA 1SVQA 3EGDA 3EFOA 4CBWG 1MDUA 1VKKA 1P8XA 1RGIG 1NMDG 4BEX1 3EGDB 1ESVS 3EFOB 2FH3A 1PD0A 2W0IA 5KYXA 1F7SA 2LJ8A 2MP4A 5KYXB 4PKGG 3EH2A 3CIPG 1PD1A 1M2OA 1QPVA 3A5LS 2HD7A 4PKHB 2VIKA 1T3XA 3CJCG 4CBUG 1VFQA 1C0GS 3FFNA 2D8BA 5KYUA 5KYNA 2NUTA 1X67A 4KEDA 2KVKA 4KEEA 5HVKD 1D4XG 5DD2A 3TU5B 2I2QA 5IVUA 2XF1A 2MV2A 4S10C 5KYUB 5HVKB 2NUTB 3DAWB 1NM1G 5FAFA 1WNJA 2FGHA 1KCQA 1COFA 1CNUA 1M2VA 3CJBG 3EH1A 1H1VG 5KYWA 4CBXG 2VACA 1V6FA 4Z94G 1AK7A 3FG7A 2FH1A 1Q8XA 1M2VB 1SVYA 5KYWB 1TMWA 3Q2BA 1D0NA 1NLVG 5KYYA 2QTVA 2VILA 3FG6A 1TVJA 1HQZ1 2NUPA 5L6WC 2XFAA 5KYYB 1J72A 2FH4A 3A5OS 1T44G 3EG9A 2NUPB 1WM4A 1AK6A 5FAEA 3EG9B 4KEFA 4PKIG 5A1MA 1P8ZG 2MOTA 4JD2H 1UDMA 1YAGG 2FH2A
chains in the Genus database with same CATH superfamily
1T2LA 1JHWA 1PCXA 1EQYS 1DEJS 1Q8GA 1WFSA 3FFKA 3EGXA 1T3YA 4LIZA 1YVNG 2LXXA 1CFYA 3EGXB 2FF6G 3L50A 2LLFA 1M4JA 3A5NS 1AHQA 2L72A 2FF3A 1C0FS 3CI5G 3A5MS 1NPHA 1SVRA 1SVQA 3EGDA 3EFOA 4CBWG 1MDUA 1VKKA 3DA7A 1P8XA 1RGIG 1NMDG 4BEX1 3EGDB 1ESVS 3EFOB 2FH3A 1PD0A 2W0IA 5KYXA 1F7SA 2LJ8A 2MP4A 5KYXB 4PKGG 3EH2A 3CIPG 1PD1A 1M2OA 1QPVA 3A5LS 2HD7A 4PKHB 2VIKA 1T3XA 3CJCG 4CBUG 1VFQA 1C0GS 3FFNA 2D8BA 5KYUA 5KYNA 2NUTA 1X67A 4KEDA 2KVKA 4KEEA 5HVKD 1D4XG 5DD2A 3TU5B 2I2QA 5IVUA 2XF1A 2MV2A 4S10C 5KYUB 5HVKB 2NUTB 3DAWB 1NM1G 5FAFA 1WNJA 2FGHA 1KCQA 1COFA 1CNUA 1M2VA 3CJBG 3EH1A 1H1VG 5KYWA 4CBXG 2VACA 1V6FA 4Z94G 1AK7A 3FG7A 2FH1A 1Q8XA 1M2VB 1SVYA 5KYWB 1TMWA 3Q2BA 1D0NA 1NLVG 5KYYA 2QTVA 2VILA 3FG6A 1TVJA 1HQZ1 2NUPA 5L6WC 2XFAA 5KYYB 1J72A 2FH4A 3A5OS 1T44G 3EG9A 2NUPB 1WM4A 1AK6A 5FAEA 3EG9B 4KEFA 4PKIG 5A1MA 1P8ZG 2MOTA 4JD2H 1UDMA 1YAGG 2FH2A
chains in the Genus database with same CATH topology
1T2LA 1JHWA 1PCXA 1EQYS 1DEJS 1Q8GA 1WFSA 3FFKA 3EGXA 1T3YA 4LIZA 1YVNG 2LXXA 1CFYA 3EGXB 2FF6G 3L50A 2LLFA 1M4JA 3A5NS 1AHQA 2L72A 2FF3A 1C0FS 3CI5G 3A5MS 1NPHA 1SVRA 1SVQA 3EGDA 3EFOA 4CBWG 1MDUA 1VKKA 3DA7A 1P8XA 1RGIG 1NMDG 4BEX1 3EGDB 1ESVS 3EFOB 2FH3A 1PD0A 2W0IA 5KYXA 1F7SA 2LJ8A 2MP4A 5KYXB 4PKGG 3EH2A 3CIPG 1PD1A 1M2OA 1QPVA 3A5LS 2HD7A 4PKHB 2VIKA 1T3XA 3CJCG 4CBUG 1VFQA 1C0GS 3FFNA 2D8BA 5KYUA 5KYNA 2NUTA 1X67A 4KEDA 2KVKA 4KEEA 5HVKD 1D4XG 5DD2A 3TU5B 2I2QA 5IVUA 2XF1A 2MV2A 4S10C 5KYUB 5HVKB 2NUTB 3DAWB 1NM1G 5FAFA 1WNJA 2FGHA 1KCQA 1COFA 1CNUA 1M2VA 3CJBG 3EH1A 1H1VG 5KYWA 4CBXG 2VACA 1V6FA 4Z94G 1AK7A 3FG7A 2FH1A 1Q8XA 1M2VB 1SVYA 5KYWB 1TMWA 3Q2BA 1D0NA 1NLVG 5KYYA 2QTVA 2VILA 3FG6A 1TVJA 1HQZ1 2NUPA 5L6WC 2XFAA 5KYYB 1J72A 2FH4A 3A5OS 1T44G 3EG9A 2NUPB 1WM4A 1AK6A 5FAEA 3EG9B 4KEFA 4PKIG 5A1MA 1P8ZG 2MOTA 4JD2H 1UDMA 1YAGG 2FH2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T2L A;  1JHW A;  1PCX A;  1EQY S;  1DEJ S;  1Q8G A;  1WFS A;  3FFK A;  3EGX A;  1T3Y A;  4LIZ A;  1YVN G;  2LXX A;  1CFY A;  3EGX B;  2FF6 G;  3L50 A;  2LLF A;  1M4J A;  3A5N S;  1AHQ A;  2L72 A;  2FF3 A;  1C0F S;  3CI5 G;  3A5M S;  1NPH A;  1SVR A;  1SVQ A;  3EGD A;  3EFO A;  4CBW G;  1MDU A;  1VKK A;  1P8X A;  1RGI G;  1NMD G;  4BEX 1;  3EGD B;  1ESV S;  3EFO B;  2FH3 A;  1PD0 A;  2W0I A;  5KYX A;  1F7S A;  2LJ8 A;  2MP4 A;  5KYX B;  4PKG G;  3EH2 A;  3CIP G;  1PD1 A;  1M2O A;  1QPV A;  3A5L S;  2HD7 A;  4PKH B;  2VIK A;  1T3X A;  3CJC G;  4CBU G;  1VFQ A;  1C0G S;  3FFN A;  2D8B A;  5KYU A;  5KYN A;  2NUT A;  1X67 A;  4KED A;  2KVK A;  4KEE A;  5HVK D;  1D4X G;  5DD2 A;  3TU5 B;  2I2Q A;  5IVU A;  2XF1 A;  2MV2 A;  4S10 C;  5KYU B;  5HVK B;  2NUT B;  3DAW B;  1NM1 G;  5FAF A;  1WNJ A;  2FGH A;  1KCQ A;  1COF A;  1CNU A;  1M2V A;  3CJB G;  3EH1 A;  1H1V G;  5KYW A;  4CBX G;  2VAC A;  1V6F A;  4Z94 G;  1AK7 A;  3FG7 A;  2FH1 A;  1Q8X A;  1M2V B;  1SVY A;  5KYW B;  1TMW A;  3Q2B A;  1D0N A;  1NLV G;  5KYY A;  2QTV A;  2VIL A;  3FG6 A;  1TVJ A;  1HQZ 1;  2NUP A;  5L6W C;  2XFA A;  5KYY B;  1J72 A;  2FH4 A;  3A5O S;  1T44 G;  3EG9 A;  2NUP B;  1WM4 A;  1AK6 A;  5FAE A;  3EG9 B;  4KEF A;  4PKI G;  5A1M A;  1P8Z G;  2MOT A;  4JD2 H;  1UDM A;  1YAG G;  2FH2 A; 
#chains in the Genus database with same CATH topology
 1T2L A;  1JHW A;  1PCX A;  1EQY S;  1DEJ S;  1Q8G A;  1WFS A;  3FFK A;  3EGX A;  1T3Y A;  4LIZ A;  1YVN G;  2LXX A;  1CFY A;  3EGX B;  2FF6 G;  3L50 A;  2LLF A;  1M4J A;  3A5N S;  1AHQ A;  2L72 A;  2FF3 A;  1C0F S;  3CI5 G;  3A5M S;  1NPH A;  1SVR A;  1SVQ A;  3EGD A;  3EFO A;  4CBW G;  1MDU A;  1VKK A;  3DA7 A;  1P8X A;  1RGI G;  1NMD G;  4BEX 1;  3EGD B;  1ESV S;  3EFO B;  2FH3 A;  1PD0 A;  2W0I A;  5KYX A;  1F7S A;  2LJ8 A;  2MP4 A;  5KYX B;  4PKG G;  3EH2 A;  3CIP G;  1PD1 A;  1M2O A;  1QPV A;  3A5L S;  2HD7 A;  4PKH B;  2VIK A;  1T3X A;  3CJC G;  4CBU G;  1VFQ A;  1C0G S;  3FFN A;  2D8B A;  5KYU A;  5KYN A;  2NUT A;  1X67 A;  4KED A;  2KVK A;  4KEE A;  5HVK D;  1D4X G;  5DD2 A;  3TU5 B;  2I2Q A;  5IVU A;  2XF1 A;  2MV2 A;  4S10 C;  5KYU B;  5HVK B;  2NUT B;  3DAW B;  1NM1 G;  5FAF A;  1WNJ A;  2FGH A;  1KCQ A;  1COF A;  1CNU A;  1M2V A;  3CJB G;  3EH1 A;  1H1V G;  5KYW A;  4CBX G;  2VAC A;  1V6F A;  4Z94 G;  1AK7 A;  3FG7 A;  2FH1 A;  1Q8X A;  1M2V B;  1SVY A;  5KYW B;  1TMW A;  3Q2B A;  1D0N A;  1NLV G;  5KYY A;  2QTV A;  2VIL A;  3FG6 A;  1TVJ A;  1HQZ 1;  2NUP A;  5L6W C;  2XFA A;  5KYY B;  1J72 A;  2FH4 A;  3A5O S;  1T44 G;  3EG9 A;  2NUP B;  1WM4 A;  1AK6 A;  5FAE A;  3EG9 B;  4KEF A;  4PKI G;  5A1M A;  1P8Z G;  2MOT A;  4JD2 H;  1UDM A;  1YAG G;  2FH2 A; 
#chains in the Genus database with same CATH homology
 1T2L A;  1JHW A;  1PCX A;  1EQY S;  1DEJ S;  1Q8G A;  1WFS A;  3FFK A;  3EGX A;  1T3Y A;  4LIZ A;  1YVN G;  2LXX A;  1CFY A;  3EGX B;  2FF6 G;  3L50 A;  2LLF A;  1M4J A;  3A5N S;  1AHQ A;  2L72 A;  2FF3 A;  1C0F S;  3CI5 G;  3A5M S;  1NPH A;  1SVR A;  1SVQ A;  3EGD A;  3EFO A;  4CBW G;  1MDU A;  1VKK A;  3DA7 A;  1P8X A;  1RGI G;  1NMD G;  4BEX 1;  3EGD B;  1ESV S;  3EFO B;  2FH3 A;  1PD0 A;  2W0I A;  5KYX A;  1F7S A;  2LJ8 A;  2MP4 A;  5KYX B;  4PKG G;  3EH2 A;  3CIP G;  1PD1 A;  1M2O A;  1QPV A;  3A5L S;  2HD7 A;  4PKH B;  2VIK A;  1T3X A;  3CJC G;  4CBU G;  1VFQ A;  1C0G S;  3FFN A;  2D8B A;  5KYU A;  5KYN A;  2NUT A;  1X67 A;  4KED A;  2KVK A;  4KEE A;  5HVK D;  1D4X G;  5DD2 A;  3TU5 B;  2I2Q A;  5IVU A;  2XF1 A;  2MV2 A;  4S10 C;  5KYU B;  5HVK B;  2NUT B;  3DAW B;  1NM1 G;  5FAF A;  1WNJ A;  2FGH A;  1KCQ A;  1COF A;  1CNU A;  1M2V A;  3CJB G;  3EH1 A;  1H1V G;  5KYW A;  4CBX G;  2VAC A;  1V6F A;  4Z94 G;  1AK7 A;  3FG7 A;  2FH1 A;  1Q8X A;  1M2V B;  1SVY A;  5KYW B;  1TMW A;  3Q2B A;  1D0N A;  1NLV G;  5KYY A;  2QTV A;  2VIL A;  3FG6 A;  1TVJ A;  1HQZ 1;  2NUP A;  5L6W C;  2XFA A;  5KYY B;  1J72 A;  2FH4 A;  3A5O S;  1T44 G;  3EG9 A;  2NUP B;  1WM4 A;  1AK6 A;  5FAE A;  3EG9 B;  4KEF A;  4PKI G;  5A1M A;  1P8Z G;  2MOT A;  4JD2 H;  1UDM A;  1YAG G;  2FH2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...