4KFZA

Crystal structure of lmo2 and anti-lmo2 vh complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
146
structure length
146
Chain Sequence
DPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKING
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords LMO-2
total genus 20
structure length 146
sequence length 146
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 4kfzA02
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 4kfzA01
1X61A 1U5SB 1CXXA 2MBVA 2CUPA 2MIUA 3MMKA 1IBIA 1M3VA 2KBXB 2XJYA 1WYHA 1X4LA 1G47A 2CUQA 1X3HA 2CORA 1X62A 2DARA 1CTLA 4JCJA 2DJ7A 2CO8A 2DLOA 4HI9B 2EHEA 2D8ZA 2D8YA 2O10A 2O13A 1X68A 2JTNA 2EGQA 2LXDA 2LZUA 2XQNT 3F6QB 2L6YB 2XJZA 3IXEB 1RUTX 1X6AA 1A7IA 1IMLA 1X63A 1X64A 1WIGA 1QLIA 2D8XA 2DFYC 1J2OA 2CURA 2L6ZC 1NYPA 2IYBE 1V6GA 4HI8B 2L4ZA 4KFZA 2YPAC 1B8TA 2CU8A
chains in the Genus database with same CATH superfamily
1X61A 2MBVA 3MMKA 1M3VA 2XJYA 1WYHA 1X4LA 2CORA 5FY0A 1X62A 2DARA 1CTLA 2DJ7A 4HI9B 2EHEA 5FXXA 3NIHA 2O13A 3AVSA 4ASKA 5A1LA 3ZPOA 1NYPA 5LKUA 4EZ4A 3NIJA 1B8TA 1J2OA 5FXVA 2CUPA 2MIUA 2KBXB 3ZLIA 5LKXA 2CO8A 2DLOA 4EYUA 2D8YA 2O10A 1X68A 2JTNA 5FXWA 3IXEB 1RUTX 1X63A 4EZHA 5FP3A 2L6ZC 3NILA 4HI8B 4KFZA 5FXZA 5LKTA 2CU8A 1U5SB 1IBIA 1G47A 2CUQA 1X3HA 3NISA 3NINA 4JCJA 5FYMA 2D8ZA 2LXDA 3F6QB 2LZUA 2L6YB 2XJZA 1X6AA 1IMLA 3NIKA 2D8XA 5FY1A 1V6GA 4UF0B 2YPAC 3AVRA 1CXXA 5FY7A 2XUEA 2EGQA 3NIMA 2XQNT 1A7IA 1WIGA 1X64A 1QLIA 2DFYC 2CURA 4UF0A 5LKZA 2IYBE 2L4ZA 4BHWA
chains in the Genus database with same CATH topology
1X61A 2MBVA 3MMKA 1M3VA 2XJYA 1WYHA 1X4LA 2CORA 5FY0A 1X62A 2DARA 1CTLA 2DJ7A 4HI9B 2EHEA 5FXXA 3NIHA 2O13A 3AVSA 4ASKA 5A1LA 3ZPOA 1NYPA 5LKUA 4EZ4A 3NIJA 1B8TA 1J2OA 5FXVA 2CUPA 2MIUA 2KBXB 3ZLIA 5LKXA 2CO8A 2DLOA 4EYUA 2D8YA 2O10A 1X68A 2JTNA 5FXWA 3IXEB 1RUTX 1X63A 4EZHA 5FP3A 2L6ZC 3NILA 4HI8B 4KFZA 5FXZA 5LKTA 2CU8A 1U5SB 1IBIA 1G47A 2CUQA 1X3HA 3NISA 3NINA 4JCJA 5FYMA 2D8ZA 2LXDA 3F6QB 2LZUA 2L6YB 2XJZA 1X6AA 1IMLA 3NIKA 2D8XA 5FY1A 1V6GA 4UF0B 2YPAC 3AVRA 1CXXA 5FY7A 2XUEA 2EGQA 3NIMA 2XQNT 1A7IA 1WIGA 1X64A 1QLIA 2DFYC 2CURA 4UF0A 5LKZA 2IYBE 2L4ZA 4BHWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X61 A;  1U5S B;  1CXX A;  2MBV A;  2CUP A;  2MIU A;  3MMK A;  1IBI A;  1M3V A;  2KBX B;  2XJY A;  1WYH A;  1X4L A;  1G47 A;  2CUQ A;  1X3H A;  2COR A;  1X62 A;  2DAR A;  1CTL A;  4JCJ A;  2DJ7 A;  2CO8 A;  2DLO A;  4HI9 B;  2EHE A;  2D8Z A;  2D8Y A;  2O10 A;  2O13 A;  1X68 A;  2JTN A;  2EGQ A;  2LXD A;  2LZU A;  2XQN T;  3F6Q B;  2L6Y B;  2XJZ A;  3IXE B;  1RUT X;  1X6A A;  1A7I A;  1IML A;  1X63 A;  1X64 A;  1WIG A;  1QLI A;  2D8X A;  2DFY C;  1J2O A;  2CUR A;  2L6Z C;  1NYP A;  2IYB E;  1V6G A;  4HI8 B;  2L4Z A;  4KFZ A;  2YPA C;  1B8T A;  2CU8 A; 
#chains in the Genus database with same CATH topology
 1X61 A;  2MBV A;  3MMK A;  1M3V A;  2XJY A;  1WYH A;  1X4L A;  2COR A;  5FY0 A;  1X62 A;  2DAR A;  1CTL A;  2DJ7 A;  4HI9 B;  2EHE A;  5FXX A;  3NIH A;  2O13 A;  3AVS A;  4ASK A;  5A1L A;  3ZPO A;  1NYP A;  5LKU A;  4EZ4 A;  3NIJ A;  1B8T A;  1J2O A;  5FXV A;  2CUP A;  2MIU A;  2KBX B;  3ZLI A;  5LKX A;  2CO8 A;  2DLO A;  4EYU A;  2D8Y A;  2O10 A;  1X68 A;  2JTN A;  5FXW A;  3IXE B;  1RUT X;  1X63 A;  4EZH A;  5FP3 A;  2L6Z C;  3NIL A;  4HI8 B;  4KFZ A;  5FXZ A;  5LKT A;  2CU8 A;  1U5S B;  1IBI A;  1G47 A;  2CUQ A;  1X3H A;  3NIS A;  3NIN A;  4JCJ A;  5FYM A;  2D8Z A;  2LXD A;  3F6Q B;  2LZU A;  2L6Y B;  2XJZ A;  1X6A A;  1IML A;  3NIK A;  2D8X A;  5FY1 A;  1V6G A;  4UF0 B;  2YPA C;  3AVR A;  1CXX A;  5FY7 A;  2XUE A;  2EGQ A;  3NIM A;  2XQN T;  1A7I A;  1WIG A;  1X64 A;  1QLI A;  2DFY C;  2CUR A;  4UF0 A;  5LKZ A;  2IYB E;  2L4Z A;  4BHW A; 
#chains in the Genus database with same CATH homology
 1X61 A;  2MBV A;  3MMK A;  1M3V A;  2XJY A;  1WYH A;  1X4L A;  2COR A;  5FY0 A;  1X62 A;  2DAR A;  1CTL A;  2DJ7 A;  4HI9 B;  2EHE A;  5FXX A;  3NIH A;  2O13 A;  3AVS A;  4ASK A;  5A1L A;  3ZPO A;  1NYP A;  5LKU A;  4EZ4 A;  3NIJ A;  1B8T A;  1J2O A;  5FXV A;  2CUP A;  2MIU A;  2KBX B;  3ZLI A;  5LKX A;  2CO8 A;  2DLO A;  4EYU A;  2D8Y A;  2O10 A;  1X68 A;  2JTN A;  5FXW A;  3IXE B;  1RUT X;  1X63 A;  4EZH A;  5FP3 A;  2L6Z C;  3NIL A;  4HI8 B;  4KFZ A;  5FXZ A;  5LKT A;  2CU8 A;  1U5S B;  1IBI A;  1G47 A;  2CUQ A;  1X3H A;  3NIS A;  3NIN A;  4JCJ A;  5FYM A;  2D8Z A;  2LXD A;  3F6Q B;  2LZU A;  2L6Y B;  2XJZ A;  1X6A A;  1IML A;  3NIK A;  2D8X A;  5FY1 A;  1V6G A;  4UF0 B;  2YPA C;  3AVR A;  1CXX A;  5FY7 A;  2XUE A;  2EGQ A;  3NIM A;  2XQN T;  1A7I A;  1WIG A;  1X64 A;  1QLI A;  2DFY C;  2CUR A;  4UF0 A;  5LKZ A;  2IYB E;  2L4Z A;  4BHW A; 
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similar chains in the Genus database (?% sequence similarity)
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