4KGHA

Crystal structure of human splunc1 lacking the secretion signal sequence
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
212
structure length
193
Chain Sequence
SPTGLAGSLTNALSNGLLSGGLLGILENLPLLDILLGKVTSVIPGLNNVIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords BPI fold-containing family A member 1
publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
source organism Homo sapiens
total genus 39
structure length 193
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kghA00
5I7LA 5I7JA 1EWFA 4M4DA 4F2AA 1BP1A 2OBDA 3ZPMA 4KGOA 4EWSA 5I7KA 4KGHA
chains in the Genus database with same CATH superfamily
2RQFA 3AOSA 3E8TA 4M4DA 4F2AA 2OBDA 2RCKA 4EWSA 1USVB 1EWFA 4KGOA 4G0SA 4KGHA 5I7LA 5I7JA 3ZPMA 3E8WA 1USUB 3H4ZA 5I7KA 3A1ZA 3UV1A 1BP1A 3N72A 3AOTA 3L6IA
chains in the Genus database with same CATH topology
2RQFA 3AOSA 3E8TA 4M4DA 4F2AA 2OBDA 2RCKA 4EWSA 1USVB 1EWFA 4KGOA 4G0SA 4KGHA 5I7LA 5I7JA 3ZPMA 3E8WA 1USUB 3H4ZA 5I7KA 3A1ZA 3UV1A 1BP1A 3N72A 3AOTA 3L6IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I7L A;  5I7J A;  1EWF A;  4M4D A;  4F2A A;  1BP1 A;  2OBD A;  3ZPM A;  4KGO A;  4EWS A;  5I7K A;  4KGH A; 
#chains in the Genus database with same CATH topology
 2RQF A;  3AOS A;  3E8T A;  4M4D A;  4F2A A;  2OBD A;  2RCK A;  4EWS A;  1USV B;  1EWF A;  4KGO A;  4G0S A;  4KGH A;  5I7L A;  5I7J A;  3ZPM A;  3E8W A;  1USU B;  3H4Z A;  5I7K A;  3A1Z A;  3UV1 A;  1BP1 A;  3N72 A;  3AOT A;  3L6I A; 
#chains in the Genus database with same CATH homology
 2RQF A;  3AOS A;  3E8T A;  4M4D A;  4F2A A;  2OBD A;  2RCK A;  4EWS A;  1USV B;  1EWF A;  4KGO A;  4G0S A;  4KGH A;  5I7L A;  5I7J A;  3ZPM A;  3E8W A;  1USU B;  3H4Z A;  5I7K A;  3A1Z A;  3UV1 A;  1BP1 A;  3N72 A;  3AOT A;  3L6I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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