4KGOA

Crystal structure of double leucine to methionine mutant human splunc1 lacking the secretion signal sequence
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
212
structure length
183
Chain Sequence
SPTGLAGSLTNALSNGLLSGGLLGIMENLPLLDIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKMDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords BPI fold-containing family A member 1
publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
source organism Homo sapiens
total genus 38
structure length 183
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kgoA00
5I7JA 4F2AA 1EWFA 4M4DA 4KGHA 5I7LA 1BP1A 2OBDA 4KGOA 3ZPMA 5I7KA 4EWSA
chains in the Genus database with same CATH superfamily
1USVB 4G0SA 2OBDA 1USUB 3ZPMA 4EWSA 5I7JA 4KGHA 4KGOA 2RCKA 5I7KA 3H4ZA 1EWFA 4M4DA 2RQFA 3A1ZA 3N72A 3UV1A 3AOTA 3L6IA 4F2AA 5I7LA 1BP1A 3AOSA 3E8WA 3E8TA
chains in the Genus database with same CATH topology
1USVB 4G0SA 2OBDA 1USUB 3ZPMA 4EWSA 5I7JA 4KGHA 4KGOA 2RCKA 5I7KA 3H4ZA 1EWFA 4M4DA 2RQFA 3A1ZA 3N72A 3UV1A 3AOTA 3L6IA 4F2AA 5I7LA 1BP1A 3AOSA 3E8WA 3E8TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I7J A;  4F2A A;  1EWF A;  4M4D A;  4KGH A;  5I7L A;  1BP1 A;  2OBD A;  4KGO A;  3ZPM A;  5I7K A;  4EWS A; 
#chains in the Genus database with same CATH topology
 1USV B;  4G0S A;  2OBD A;  1USU B;  3ZPM A;  4EWS A;  5I7J A;  4KGH A;  4KGO A;  2RCK A;  5I7K A;  3H4Z A;  1EWF A;  4M4D A;  2RQF A;  3A1Z A;  3N72 A;  3UV1 A;  3AOT A;  3L6I A;  4F2A A;  5I7L A;  1BP1 A;  3AOS A;  3E8W A;  3E8T A; 
#chains in the Genus database with same CATH homology
 1USV B;  4G0S A;  2OBD A;  1USU B;  3ZPM A;  4EWS A;  5I7J A;  4KGH A;  4KGO A;  2RCK A;  5I7K A;  3H4Z A;  1EWF A;  4M4D A;  2RQF A;  3A1Z A;  3N72 A;  3UV1 A;  3AOT A;  3L6I A;  4F2A A;  5I7L A;  1BP1 A;  3AOS A;  3E8W A;  3E8T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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