4KVYA

Crystal structure of aspergillus terreus aristolochene synthase complexed with (1s,8s,9ar)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
304
structure length
304
Chain Sequence
LEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTSKTAHSEGGILCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase.
pubmed doi rcsb
molecule keywords Aristolochene synthase
molecule tags Lyase/lyase inhibitor
source organism Aspergillus terreus
total genus 130
structure length 304
sequence length 304
chains with identical sequence B, C, D
ec nomenclature ec 4.2.3.9: Aristolochene synthase.
pdb deposition date 2013-05-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4kvyA00
4FJQA 1WL2A 3V66A 3LLWA 4LZ3A 3VJ9A 2Q9YA 4LZ0A 2ZCSA 1UBYA 3NPRA 3DYFA 3ACXA 3P41A 4MC8A 3Q1OA 2H8OA 4DXJA 5E8LA 3BNXA 3NF2A 1N24A 2ZEVA 4QPFA 4F6VA 2Z52A 5E8HA 3TFNA 3VJDA 4QXSF 5AHUB 5DGMF 2EWGA 2F7MF 3KROB 4LA5A 3LMDA 4LOBA 3APZA 4EA1A 3AQBB 1EZFA 5B0IA 3ADZA 3WJOA 2ZY1A 4LPGF 2E8VA 2P1CA 1KIYA 5DJPF 4RXCA 1JFAA 3KRFB 1WY0A 5B0JA 2Z4WA 3SDUA 1WKZA 4KQ5A 4RNQA 3MZVA 5DJVF 3RYEA 3N5HF 5DGNF 4F6XA 4KVYA 2VF6A 5E8KA 1DI1A 4GA3A 4KQSA 5AFXA 4XQTF 5IM1A 1V4JA 3KROA 4E9ZA 1YJ4A 2E95A 3EFQA 3ZL6A 1JFGA 3P8RA 3WCDA 5ILDA 5DHIA 3WCFA 3CC9A 4OGUA 5B01A 5HNAA 3WCIA 3Q2QA 1WMWA 1HX9A 4ZQ8A 2E8WA 2J1OA 4DWBA 3WEHA 4MC0A 5ILIA 4OMHA 3LJIA 4P0WA 5HN7A 3KRFA 1VG3A 4HD1A 3WJKA 2ZCOA 4LA6A 3AE0A 4KQUA 4MC3A 3N46F 1DGPA 3IPIA 4KWDA 3TS7A 4KFAA 3G4DA 5HN8A 3AQCB 5ILKA 4PVXF 4H5EF 2AETA 2J5CA 3LEEA 5C05A 5CG5A 1WL3A 3N3LF 5JV0F 2O1OA 3KRCB 3LG5A 4XQSF 3ACWA 3N5JF 3S9VA 3ICZA 2Z4ZA 4LZCA 2AELA 4DHDA 3N45F 3WCCA 3N0GA 4E9UA 4NFKF 5DGSF 4KPDA 3WCAA 2J1PA 4NFJF 1V4EA 2E8XA 5IK9A 2AZKA 4JZXA 2F92F 3Q2ZA 5EROA 3N1WF 4JZBA 1N1ZA 4DI5A 3LSNA 2Q9ZA 1PS1A 4NKFA 3ZMCA 2F89F 4KKMA 2E91A 5B0LA 3KRCA 1YQ7A 5EAUA 3TC1A 3N49F 3WC9A 1N23A 3KRAB 5DZ2A 3VJAA 4KK2A 3M00A 3LVSA 5IK0A 5A0KA 3OACB 4WK5A 3KB9A 4P0XA 2FTZA 4RXDA 5I1UA 5EATA 1YYRA 2OPMA 4OKMA 3LDWA 3W7FA 2I19A 3CP6A 1YYQA 3WCHA 3WE9A 3ZCDA 3PYAA 5IKHA 2ONGA 5B0KA 4LFVF 1HXAA 3S4JA 3WEIA 3KBKA 5H9DA 5ERMA 5IMPA 5ILYA 1VG6A 4GP1A 4KPJA 1V4IA 4FP4A 3M9UA 3KRAA 3LK5A 3WCJA 2PS6A 1VG7A 3VJ8A 2E90A 3OACA 3PDEA 4LPHF 3N6KF 5IMIA 1RQIA 5JA0F 5JV2F 2AZLA 4E1EA 2PS7A 5ILZA 4KVIA 2ONHA 3MAVA 5IVGA 4DWGA 3M0GA 3VJCA 3OYRA 5A0IA 5IN8A 3PYBA 5B0MA 1FPSA 4LIXA 1YHLA 5JUZF 2E94A 4EA0A 2QISA 1UBWA 2E8UA 4RYPA 4EA2A 1RTRA 1RQJA 3V1XA 2Z7HA 3NPKA 3IBAA 3QKCA 1N1BA 3P5PA 3M02A 3N0FA 1WL0A 4XQRF 3WSBA 4LLSA 3ZMBA 4LTVA 3N1VF 3LZ9A 3WEKA 1YYUA 3SAEA 2OGDA 2AZJA 2Z78A 3LOMA 3SDQA 3V1VA 2PS5A 3BNYA 1HM4A 5IMNA 1N20A 3LGZB 3EZ3A 4GP2A 2DH4A 5EASA 3OABB 3WSAA 2E92A 1VG4A 3DYHA 5IL8A 3WEFA 4DZWA 1YYSA 3RBMA 3P5RA 4JVJF 2Z4VA 3ICNA 2PS8A 3ZOUA 3NRIA 5DHKA 1UBVA 1YYTA 4Q23A 3KRPB 2Q58A 4GAXA 2ZCRA 4K10A 1N21A 3M01A 3ID0A 5DJRF 4LFEA 4RXAA 1V4HA 3WJNA 2F9KF 3WEGA 5JV1F 2Z4YA 4N9UA 4KUXA 5AYPA 3SDRA 5DW7A 2F8CF 2Z50A 4KVWA 3WCGA 3SDTA 3B7LA 4L2XF 5ILJA 3OABA 3WCEA 4DEMF 3TFPA 5ER8A 2AEKA 4NUAA 4OKZA 3VJEA 3WCBA 4NFIF 1N22A 1V4KA 3RMGA 1UBXA 4NG6A 4LLTA 3ACYA 3WEJA 5B02A 3N3DA 2PS4A 3LGKA 4N1ZF 5IKAA 1ZW5A 1HXGA 3KRPA 3RYWA 3CKEA 3P8LA 4NKEA 5ERNA 3ASXA 4LUUA 1YV5A 2Z7IA 5KSXF 3UCAA 4H5DF 5CG6A 5HN9A 3ICMA 4LXWA 3VJBA 2FORA 4OMGA 1YHKA 1VG2A 4F62A 5IK6A 2E93A 4JXYA 2F8ZF 3PH7A 4RXEA 3WCMA 4PVYF 2ZEUA 4JYXA 3EGTA 3TFVA 4P0VA 3DYGA 1KIZA 2F94F 5B03A 2ZCQA 2E4OA 2Z4XA 5A0JA 5AELA 3G4FA 2RAHA 3QQVA 1WL1A 2Q80A 3ICKA 4UMJA 1HXCA 3PKOA 4H5CF 5ILHA 3WCLA 3SDVA 4JXNA 1HM7A 2OPNA 5DIQF 4LFGA 4KVDA 2E8TA 1YHMA 5IL3A 3AQ0A 5B00A 3Q30A 2OA6A 4LTZA
chains in the Genus database with same CATH superfamily
4FJQA 1WL2A 3V66A 3LLWA 4LZ3A 3VJ9A 2Q9YA 4LZ0A 2ZCSA 1UBYA 3NPRA 3DYFA 3ACXA 3P41A 4MC8A 3Q1OA 2H8OA 4DXJA 5E8LA 3BNXA 3NF2A 1N24A 2ZEVA 4QPFA 4F6VA 2Z52A 5E8HA 3TFNA 3VJDA 4QXSF 5AHUB 5DGMF 2EWGA 2F7MF 3KROB 4LA5A 3LMDA 4LOBA 3APZA 4EA1A 3AQBB 1EZFA 5B0IA 3ADZA 3WJOA 2ZY1A 4LPGF 2E8VA 2P1CA 1KIYA 5DJPF 4RXCA 1JFAA 3KRFB 1WY0A 5B0JA 2Z4WA 3SDUA 1WKZA 4KQ5A 4RNQA 3MZVA 5DJVF 3RYEA 3N5HF 5DGNF 4F6XA 4KVYA 2VF6A 5E8KA 1DI1A 4GA3A 4KQSA 5AFXA 4XQTF 5IM1A 1V4JA 3KROA 4E9ZA 1YJ4A 2E95A 3EFQA 3ZL6A 1JFGA 3P8RA 3WCDA 5ILDA 5DHIA 3WCFA 3CC9A 4OGUA 5B01A 5HNAA 3WCIA 3Q2QA 1WMWA 1HX9A 4ZQ8A 2E8WA 2J1OA 4DWBA 3WEHA 4MC0A 5ILIA 4OMHA 3LJIA 4P0WA 5HN7A 3KRFA 1VG3A 4HD1A 3WJKA 2ZCOA 4LA6A 3AE0A 4KQUA 4MC3A 3N46F 1DGPA 3IPIA 4KWDA 3TS7A 4KFAA 3G4DA 5HN8A 3AQCB 5ILKA 4PVXF 4H5EF 2AETA 2J5CA 3LEEA 5C05A 5CG5A 1WL3A 3N3LF 5JV0F 2O1OA 3KRCB 3LG5A 4XQSF 3ACWA 3N5JF 3S9VA 3ICZA 2Z4ZA 4LZCA 2AELA 4DHDA 3N45F 3WCCA 3N0GA 4E9UA 4NFKF 5DGSF 4KPDA 3WCAA 2J1PA 4NFJF 1V4EA 2E8XA 5IK9A 2AZKA 4JZXA 2F92F 3Q2ZA 5EROA 3N1WF 4JZBA 1N1ZA 4DI5A 3LSNA 2Q9ZA 1PS1A 4NKFA 3ZMCA 2F89F 4KKMA 2E91A 5B0LA 3KRCA 1YQ7A 5EAUA 3TC1A 3N49F 3WC9A 1N23A 3KRAB 5DZ2A 3VJAA 4KK2A 3M00A 3LVSA 5IK0A 5A0KA 3OACB 4WK5A 3KB9A 4P0XA 2FTZA 4RXDA 5I1UA 5EATA 1YYRA 2OPMA 4OKMA 3LDWA 3W7FA 2I19A 3CP6A 1YYQA 3WCHA 3WE9A 3ZCDA 3PYAA 5IKHA 2ONGA 5B0KA 4LFVF 1HXAA 3S4JA 3WEIA 3KBKA 5H9DA 5ERMA 5IMPA 5ILYA 1VG6A 4GP1A 4KPJA 1V4IA 4FP4A 3M9UA 3KRAA 3LK5A 3WCJA 2PS6A 1VG7A 3VJ8A 2E90A 3OACA 3PDEA 4LPHF 3N6KF 5IMIA 1RQIA 5JA0F 5JV2F 2AZLA 4E1EA 2PS7A 5ILZA 4KVIA 2ONHA 3MAVA 5IVGA 4DWGA 3M0GA 3VJCA 3OYRA 5A0IA 5IN8A 3PYBA 5B0MA 1FPSA 4LIXA 1YHLA 5JUZF 2E94A 4EA0A 2QISA 1UBWA 2E8UA 4RYPA 4EA2A 1RTRA 1RQJA 3V1XA 2Z7HA 3NPKA 3IBAA 3QKCA 1N1BA 3P5PA 3M02A 3N0FA 1WL0A 4XQRF 3WSBA 4LLSA 3ZMBA 4LTVA 3N1VF 3LZ9A 3WEKA 1YYUA 3SAEA 2OGDA 2AZJA 2Z78A 3LOMA 3SDQA 3V1VA 2PS5A 3BNYA 1HM4A 5IMNA 1N20A 3LGZB 3EZ3A 4GP2A 2DH4A 5EASA 3OABB 3WSAA 2E92A 1VG4A 3DYHA 5IL8A 3WEFA 4DZWA 1YYSA 3RBMA 3P5RA 4JVJF 2Z4VA 3ICNA 2PS8A 3ZOUA 3NRIA 5DHKA 1UBVA 1YYTA 4Q23A 3KRPB 2Q58A 4GAXA 2ZCRA 4K10A 1N21A 3M01A 3ID0A 5DJRF 4LFEA 4RXAA 1V4HA 3WJNA 2F9KF 3WEGA 5JV1F 2Z4YA 4N9UA 4KUXA 5AYPA 3SDRA 5DW7A 2F8CF 2Z50A 4KVWA 3WCGA 3SDTA 3B7LA 4L2XF 5ILJA 3OABA 3WCEA 4DEMF 3TFPA 5ER8A 2AEKA 4NUAA 4OKZA 3VJEA 3WCBA 4NFIF 1N22A 1V4KA 3RMGA 1UBXA 4NG6A 4LLTA 3ACYA 3WEJA 5B02A 3N3DA 2PS4A 3LGKA 4N1ZF 5IKAA 1ZW5A 1HXGA 3KRPA 3RYWA 3CKEA 3P8LA 4NKEA 5ERNA 3ASXA 4LUUA 1YV5A 2Z7IA 5KSXF 3UCAA 4H5DF 5CG6A 5HN9A 3ICMA 4LXWA 3VJBA 2FORA 4OMGA 1YHKA 1VG2A 4F62A 5IK6A 2E93A 4JXYA 2F8ZF 3PH7A 4RXEA 3WCMA 4PVYF 2ZEUA 4JYXA 3EGTA 3TFVA 4P0VA 3DYGA 1KIZA 2F94F 5B03A 2ZCQA 2E4OA 2Z4XA 5A0JA 5AELA 3G4FA 2RAHA 3QQVA 1WL1A 2Q80A 3ICKA 4UMJA 1HXCA 3PKOA 4H5CF 5ILHA 3WCLA 3SDVA 4JXNA 1HM7A 2OPNA 5DIQF 4LFGA 4KVDA 2E8TA 1YHMA 5IL3A 3AQ0A 5B00A 3Q30A 2OA6A 4LTZA
chains in the Genus database with same CATH topology
4FJQA 1WL2A 3V66A 3LLWA 4LZ3A 3VJ9A 2Q9YA 4LZ0A 2ZCSA 1UBYA 3NPRA 3DYFA 3ACXA 3P41A 4MC8A 3Q1OA 2H8OA 4DXJA 5E8LA 3BNXA 3NF2A 1N24A 2ZEVA 4QPFA 4F6VA 2Z52A 5E8HA 3TFNA 3VJDA 4QXSF 5AHUB 5DGMF 2EWGA 2F7MF 3KROB 4LA5A 3LMDA 4LOBA 3APZA 4EA1A 3AQBB 1EZFA 5B0IA 3ADZA 3WJOA 2ZY1A 4LPGF 2E8VA 2P1CA 1KIYA 5DJPF 4RXCA 1JFAA 3KRFB 1WY0A 5B0JA 2Z4WA 3SDUA 1WKZA 4KQ5A 4RNQA 3MZVA 5DJVF 3RYEA 3N5HF 5DGNF 4F6XA 4KVYA 2VF6A 5E8KA 1DI1A 4GA3A 4KQSA 5AFXA 4XQTF 5IM1A 1V4JA 3KROA 4E9ZA 1YJ4A 2E95A 3EFQA 3ZL6A 1JFGA 3P8RA 3WCDA 5ILDA 5DHIA 3WCFA 3CC9A 4OGUA 5B01A 5HNAA 3WCIA 3Q2QA 1WMWA 1HX9A 4ZQ8A 2E8WA 2J1OA 4DWBA 3WEHA 4MC0A 5ILIA 4OMHA 3LJIA 4P0WA 5HN7A 3KRFA 1VG3A 4HD1A 3WJKA 2ZCOA 4LA6A 3AE0A 4KQUA 4MC3A 3N46F 1DGPA 3IPIA 4KWDA 3TS7A 4KFAA 3G4DA 5HN8A 3AQCB 5ILKA 4PVXF 4H5EF 2AETA 2J5CA 3LEEA 5C05A 5CG5A 1WL3A 3N3LF 5JV0F 2O1OA 3KRCB 3LG5A 4XQSF 3ACWA 3N5JF 3S9VA 3ICZA 2Z4ZA 4LZCA 2AELA 4DHDA 3N45F 3WCCA 3N0GA 4E9UA 4NFKF 5DGSF 4KPDA 3WCAA 2J1PA 4NFJF 1V4EA 2E8XA 5IK9A 2AZKA 4JZXA 2F92F 3Q2ZA 5EROA 3N1WF 4JZBA 1N1ZA 4DI5A 3LSNA 2Q9ZA 1PS1A 4NKFA 3ZMCA 2F89F 4KKMA 2E91A 5B0LA 3KRCA 1YQ7A 5EAUA 3TC1A 3N49F 3WC9A 1N23A 3KRAB 5DZ2A 3VJAA 4KK2A 3M00A 3LVSA 5IK0A 5A0KA 3OACB 4WK5A 3KB9A 4P0XA 2FTZA 4RXDA 5I1UA 5EATA 1YYRA 2OPMA 4OKMA 3LDWA 3W7FA 2I19A 3CP6A 1YYQA 3WCHA 3WE9A 3ZCDA 3PYAA 5IKHA 2ONGA 5B0KA 4LFVF 1HXAA 3S4JA 3WEIA 3KBKA 5H9DA 5ERMA 5IMPA 5ILYA 1VG6A 4GP1A 4KPJA 1V4IA 4FP4A 3M9UA 3KRAA 3LK5A 3WCJA 2PS6A 1VG7A 3VJ8A 2E90A 3OACA 3PDEA 4LPHF 3N6KF 5IMIA 1RQIA 5JA0F 5JV2F 2AZLA 4E1EA 2PS7A 5ILZA 4KVIA 2ONHA 3MAVA 5IVGA 4DWGA 3M0GA 3VJCA 3OYRA 5A0IA 5IN8A 3PYBA 5B0MA 1FPSA 4LIXA 1YHLA 5JUZF 2E94A 4EA0A 2QISA 1UBWA 2E8UA 4RYPA 4EA2A 1RTRA 1RQJA 3V1XA 2Z7HA 3NPKA 3IBAA 3QKCA 1N1BA 3P5PA 3M02A 3N0FA 1WL0A 4XQRF 3WSBA 4LLSA 3ZMBA 4LTVA 3N1VF 3LZ9A 3WEKA 1YYUA 3SAEA 2OGDA 2AZJA 2Z78A 3LOMA 3SDQA 3V1VA 2PS5A 3BNYA 1HM4A 5IMNA 1N20A 3LGZB 3EZ3A 4GP2A 2DH4A 5EASA 3OABB 3WSAA 2E92A 1VG4A 3DYHA 5IL8A 3WEFA 4DZWA 1YYSA 3RBMA 3P5RA 4JVJF 2Z4VA 3ICNA 2PS8A 3ZOUA 3NRIA 5DHKA 1UBVA 1YYTA 4Q23A 3KRPB 2Q58A 4GAXA 2ZCRA 4K10A 1N21A 3M01A 3ID0A 5DJRF 4LFEA 4RXAA 1V4HA 3WJNA 2F9KF 3WEGA 5JV1F 2Z4YA 4N9UA 4KUXA 5AYPA 3SDRA 5DW7A 2F8CF 2Z50A 4KVWA 3WCGA 3SDTA 3B7LA 4L2XF 5ILJA 3OABA 3WCEA 4DEMF 3TFPA 5ER8A 2AEKA 4NUAA 4OKZA 3VJEA 3WCBA 4NFIF 1N22A 1V4KA 3RMGA 1UBXA 4NG6A 4LLTA 3ACYA 3WEJA 5B02A 3N3DA 2PS4A 3LGKA 4N1ZF 5IKAA 1ZW5A 1HXGA 3KRPA 3RYWA 3CKEA 3P8LA 4NKEA 5ERNA 3ASXA 4LUUA 1YV5A 2Z7IA 5KSXF 3UCAA 4H5DF 5CG6A 5HN9A 3ICMA 4LXWA 3VJBA 2FORA 4OMGA 1YHKA 1VG2A 4F62A 5IK6A 2E93A 4JXYA 2F8ZF 3PH7A 4RXEA 3WCMA 4PVYF 2ZEUA 4JYXA 3EGTA 3TFVA 4P0VA 3DYGA 1KIZA 2F94F 5B03A 2ZCQA 2E4OA 2Z4XA 5A0JA 5AELA 3G4FA 2RAHA 3QQVA 1WL1A 2Q80A 3ICKA 4UMJA 1HXCA 3PKOA 4H5CF 5ILHA 3WCLA 3SDVA 4JXNA 1HM7A 2OPNA 5DIQF 4LFGA 4KVDA 2E8TA 1YHMA 5IL3A 3AQ0A 5B00A 3Q30A 2OA6A 4LTZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4FJQ A;  1WL2 A;  3V66 A;  3LLW A;  4LZ3 A;  3VJ9 A;  2Q9Y A;  4LZ0 A;  2ZCS A;  1UBY A;  3NPR A;  3DYF A;  3ACX A;  3P41 A;  4MC8 A;  3Q1O A;  2H8O A;  4DXJ A;  5E8L A;  3BNX A;  3NF2 A;  1N24 A;  2ZEV A;  4QPF A;  4F6V A;  2Z52 A;  5E8H A;  3TFN A;  3VJD A;  4QXS F;  5AHU B;  5DGM F;  2EWG A;  2F7M F;  3KRO B;  4LA5 A;  3LMD A;  4LOB A;  3APZ A;  4EA1 A;  3AQB B;  1EZF A;  5B0I A;  3ADZ A;  3WJO A;  2ZY1 A;  4LPG F;  2E8V A;  2P1C A;  1KIY A;  5DJP F;  4RXC A;  1JFA A;  3KRF B;  1WY0 A;  5B0J A;  2Z4W A;  3SDU A;  1WKZ A;  4KQ5 A;  4RNQ A;  3MZV A;  5DJV F;  3RYE A;  3N5H F;  5DGN F;  4F6X A;  4KVY A;  2VF6 A;  5E8K A;  1DI1 A;  4GA3 A;  4KQS A;  5AFX A;  4XQT F;  5IM1 A;  1V4J A;  3KRO A;  4E9Z A;  1YJ4 A;  2E95 A;  3EFQ A;  3ZL6 A;  1JFG A;  3P8R A;  3WCD A;  5ILD A;  5DHI A;  3WCF A;  3CC9 A;  4OGU A;  5B01 A;  5HNA A;  3WCI A;  3Q2Q A;  1WMW A;  1HX9 A;  4ZQ8 A;  2E8W A;  2J1O A;  4DWB A;  3WEH A;  4MC0 A;  5ILI A;  4OMH A;  3LJI A;  4P0W A;  5HN7 A;  3KRF A;  1VG3 A;  4HD1 A;  3WJK A;  2ZCO A;  4LA6 A;  3AE0 A;  4KQU A;  4MC3 A;  3N46 F;  1DGP A;  3IPI A;  4KWD A;  3TS7 A;  4KFA A;  3G4D A;  5HN8 A;  3AQC B;  5ILK A;  4PVX F;  4H5E F;  2AET A;  2J5C A;  3LEE A;  5C05 A;  5CG5 A;  1WL3 A;  3N3L F;  5JV0 F;  2O1O A;  3KRC B;  3LG5 A;  4XQS F;  3ACW A;  3N5J F;  3S9V A;  3ICZ A;  2Z4Z A;  4LZC A;  2AEL A;  4DHD A;  3N45 F;  3WCC A;  3N0G A;  4E9U A;  4NFK F;  5DGS F;  4KPD A;  3WCA A;  2J1P A;  4NFJ F;  1V4E A;  2E8X A;  5IK9 A;  2AZK A;  4JZX A;  2F92 F;  3Q2Z A;  5ERO A;  3N1W F;  4JZB A;  1N1Z A;  4DI5 A;  3LSN A;  2Q9Z A;  1PS1 A;  4NKF A;  3ZMC A;  2F89 F;  4KKM A;  2E91 A;  5B0L A;  3KRC A;  1YQ7 A;  5EAU A;  3TC1 A;  3N49 F;  3WC9 A;  1N23 A;  3KRA B;  5DZ2 A;  3VJA A;  4KK2 A;  3M00 A;  3LVS A;  5IK0 A;  5A0K A;  3OAC B;  4WK5 A;  3KB9 A;  4P0X A;  2FTZ A;  4RXD A;  5I1U A;  5EAT A;  1YYR A;  2OPM A;  4OKM A;  3LDW A;  3W7F A;  2I19 A;  3CP6 A;  1YYQ A;  3WCH A;  3WE9 A;  3ZCD A;  3PYA A;  5IKH A;  2ONG A;  5B0K A;  4LFV F;  1HXA A;  3S4J A;  3WEI A;  3KBK A;  5H9D A;  5ERM A;  5IMP A;  5ILY A;  1VG6 A;  4GP1 A;  4KPJ A;  1V4I A;  4FP4 A;  3M9U A;  3KRA A;  3LK5 A;  3WCJ A;  2PS6 A;  1VG7 A;  3VJ8 A;  2E90 A;  3OAC A;  3PDE A;  4LPH F;  3N6K F;  5IMI A;  1RQI A;  5JA0 F;  5JV2 F;  2AZL A;  4E1E A;  2PS7 A;  5ILZ A;  4KVI A;  2ONH A;  3MAV A;  5IVG A;  4DWG A;  3M0G A;  3VJC A;  3OYR A;  5A0I A;  5IN8 A;  3PYB A;  5B0M A;  1FPS A;  4LIX A;  1YHL A;  5JUZ F;  2E94 A;  4EA0 A;  2QIS A;  1UBW A;  2E8U A;  4RYP A;  4EA2 A;  1RTR A;  1RQJ A;  3V1X A;  2Z7H A;  3NPK A;  3IBA A;  3QKC A;  1N1B A;  3P5P A;  3M02 A;  3N0F A;  1WL0 A;  4XQR F;  3WSB A;  4LLS A;  3ZMB A;  4LTV A;  3N1V F;  3LZ9 A;  3WEK A;  1YYU A;  3SAE A;  2OGD A;  2AZJ A;  2Z78 A;  3LOM A;  3SDQ A;  3V1V A;  2PS5 A;  3BNY A;  1HM4 A;  5IMN A;  1N20 A;  3LGZ B;  3EZ3 A;  4GP2 A;  2DH4 A;  5EAS A;  3OAB B;  3WSA A;  2E92 A;  1VG4 A;  3DYH A;  5IL8 A;  3WEF A;  4DZW A;  1YYS A;  3RBM A;  3P5R A;  4JVJ F;  2Z4V A;  3ICN A;  2PS8 A;  3ZOU A;  3NRI A;  5DHK A;  1UBV A;  1YYT A;  4Q23 A;  3KRP B;  2Q58 A;  4GAX A;  2ZCR A;  4K10 A;  1N21 A;  3M01 A;  3ID0 A;  5DJR F;  4LFE A;  4RXA A;  1V4H A;  3WJN A;  2F9K F;  3WEG A;  5JV1 F;  2Z4Y A;  4N9U A;  4KUX A;  5AYP A;  3SDR A;  5DW7 A;  2F8C F;  2Z50 A;  4KVW A;  3WCG A;  3SDT A;  3B7L A;  4L2X F;  5ILJ A;  3OAB A;  3WCE A;  4DEM F;  3TFP A;  5ER8 A;  2AEK A;  4NUA A;  4OKZ A;  3VJE A;  3WCB A;  4NFI F;  1N22 A;  1V4K A;  3RMG A;  1UBX A;  4NG6 A;  4LLT A;  3ACY A;  3WEJ A;  5B02 A;  3N3D A;  2PS4 A;  3LGK A;  4N1Z F;  5IKA A;  1ZW5 A;  1HXG A;  3KRP A;  3RYW A;  3CKE A;  3P8L A;  4NKE A;  5ERN A;  3ASX A;  4LUU A;  1YV5 A;  2Z7I A;  5KSX F;  3UCA A;  4H5D F;  5CG6 A;  5HN9 A;  3ICM A;  4LXW A;  3VJB A;  2FOR A;  4OMG A;  1YHK A;  1VG2 A;  4F62 A;  5IK6 A;  2E93 A;  4JXY A;  2F8Z F;  3PH7 A;  4RXE A;  3WCM A;  4PVY F;  2ZEU A;  4JYX A;  3EGT A;  3TFV A;  4P0V A;  3DYG A;  1KIZ A;  2F94 F;  5B03 A;  2ZCQ A;  2E4O A;  2Z4X A;  5A0J A;  5AEL A;  3G4F A;  2RAH A;  3QQV A;  1WL1 A;  2Q80 A;  3ICK A;  4UMJ A;  1HXC A;  3PKO A;  4H5C F;  5ILH A;  3WCL A;  3SDV A;  4JXN A;  1HM7 A;  2OPN A;  5DIQ F;  4LFG A;  4KVD A;  2E8T A;  1YHM A;  5IL3 A;  3AQ0 A;  5B00 A;  3Q30 A;  2OA6 A;  4LTZ A; 
#chains in the Genus database with same CATH topology
 4FJQ A;  1WL2 A;  3V66 A;  3LLW A;  4LZ3 A;  3VJ9 A;  2Q9Y A;  4LZ0 A;  2ZCS A;  1UBY A;  3NPR A;  3DYF A;  3ACX A;  3P41 A;  4MC8 A;  3Q1O A;  2H8O A;  4DXJ A;  5E8L A;  3BNX A;  3NF2 A;  1N24 A;  2ZEV A;  4QPF A;  4F6V A;  2Z52 A;  5E8H A;  3TFN A;  3VJD A;  4QXS F;  5AHU B;  5DGM F;  2EWG A;  2F7M F;  3KRO B;  4LA5 A;  3LMD A;  4LOB A;  3APZ A;  4EA1 A;  3AQB B;  1EZF A;  5B0I A;  3ADZ A;  3WJO A;  2ZY1 A;  4LPG F;  2E8V A;  2P1C A;  1KIY A;  5DJP F;  4RXC A;  1JFA A;  3KRF B;  1WY0 A;  5B0J A;  2Z4W A;  3SDU A;  1WKZ A;  4KQ5 A;  4RNQ A;  3MZV A;  5DJV F;  3RYE A;  3N5H F;  5DGN F;  4F6X A;  4KVY A;  2VF6 A;  5E8K A;  1DI1 A;  4GA3 A;  4KQS A;  5AFX A;  4XQT F;  5IM1 A;  1V4J A;  3KRO A;  4E9Z A;  1YJ4 A;  2E95 A;  3EFQ A;  3ZL6 A;  1JFG A;  3P8R A;  3WCD A;  5ILD A;  5DHI A;  3WCF A;  3CC9 A;  4OGU A;  5B01 A;  5HNA A;  3WCI A;  3Q2Q A;  1WMW A;  1HX9 A;  4ZQ8 A;  2E8W A;  2J1O A;  4DWB A;  3WEH A;  4MC0 A;  5ILI A;  4OMH A;  3LJI A;  4P0W A;  5HN7 A;  3KRF A;  1VG3 A;  4HD1 A;  3WJK A;  2ZCO A;  4LA6 A;  3AE0 A;  4KQU A;  4MC3 A;  3N46 F;  1DGP A;  3IPI A;  4KWD A;  3TS7 A;  4KFA A;  3G4D A;  5HN8 A;  3AQC B;  5ILK A;  4PVX F;  4H5E F;  2AET A;  2J5C A;  3LEE A;  5C05 A;  5CG5 A;  1WL3 A;  3N3L F;  5JV0 F;  2O1O A;  3KRC B;  3LG5 A;  4XQS F;  3ACW A;  3N5J F;  3S9V A;  3ICZ A;  2Z4Z A;  4LZC A;  2AEL A;  4DHD A;  3N45 F;  3WCC A;  3N0G A;  4E9U A;  4NFK F;  5DGS F;  4KPD A;  3WCA A;  2J1P A;  4NFJ F;  1V4E A;  2E8X A;  5IK9 A;  2AZK A;  4JZX A;  2F92 F;  3Q2Z A;  5ERO A;  3N1W F;  4JZB A;  1N1Z A;  4DI5 A;  3LSN A;  2Q9Z A;  1PS1 A;  4NKF A;  3ZMC A;  2F89 F;  4KKM A;  2E91 A;  5B0L A;  3KRC A;  1YQ7 A;  5EAU A;  3TC1 A;  3N49 F;  3WC9 A;  1N23 A;  3KRA B;  5DZ2 A;  3VJA A;  4KK2 A;  3M00 A;  3LVS A;  5IK0 A;  5A0K A;  3OAC B;  4WK5 A;  3KB9 A;  4P0X A;  2FTZ A;  4RXD A;  5I1U A;  5EAT A;  1YYR A;  2OPM A;  4OKM A;  3LDW A;  3W7F A;  2I19 A;  3CP6 A;  1YYQ A;  3WCH A;  3WE9 A;  3ZCD A;  3PYA A;  5IKH A;  2ONG A;  5B0K A;  4LFV F;  1HXA A;  3S4J A;  3WEI A;  3KBK A;  5H9D A;  5ERM A;  5IMP A;  5ILY A;  1VG6 A;  4GP1 A;  4KPJ A;  1V4I A;  4FP4 A;  3M9U A;  3KRA A;  3LK5 A;  3WCJ A;  2PS6 A;  1VG7 A;  3VJ8 A;  2E90 A;  3OAC A;  3PDE A;  4LPH F;  3N6K F;  5IMI A;  1RQI A;  5JA0 F;  5JV2 F;  2AZL A;  4E1E A;  2PS7 A;  5ILZ A;  4KVI A;  2ONH A;  3MAV A;  5IVG A;  4DWG A;  3M0G A;  3VJC A;  3OYR A;  5A0I A;  5IN8 A;  3PYB A;  5B0M A;  1FPS A;  4LIX A;  1YHL A;  5JUZ F;  2E94 A;  4EA0 A;  2QIS A;  1UBW A;  2E8U A;  4RYP A;  4EA2 A;  1RTR A;  1RQJ A;  3V1X A;  2Z7H A;  3NPK A;  3IBA A;  3QKC A;  1N1B A;  3P5P A;  3M02 A;  3N0F A;  1WL0 A;  4XQR F;  3WSB A;  4LLS A;  3ZMB A;  4LTV A;  3N1V F;  3LZ9 A;  3WEK A;  1YYU A;  3SAE A;  2OGD A;  2AZJ A;  2Z78 A;  3LOM A;  3SDQ A;  3V1V A;  2PS5 A;  3BNY A;  1HM4 A;  5IMN A;  1N20 A;  3LGZ B;  3EZ3 A;  4GP2 A;  2DH4 A;  5EAS A;  3OAB B;  3WSA A;  2E92 A;  1VG4 A;  3DYH A;  5IL8 A;  3WEF A;  4DZW A;  1YYS A;  3RBM A;  3P5R A;  4JVJ F;  2Z4V A;  3ICN A;  2PS8 A;  3ZOU A;  3NRI A;  5DHK A;  1UBV A;  1YYT A;  4Q23 A;  3KRP B;  2Q58 A;  4GAX A;  2ZCR A;  4K10 A;  1N21 A;  3M01 A;  3ID0 A;  5DJR F;  4LFE A;  4RXA A;  1V4H A;  3WJN A;  2F9K F;  3WEG A;  5JV1 F;  2Z4Y A;  4N9U A;  4KUX A;  5AYP A;  3SDR A;  5DW7 A;  2F8C F;  2Z50 A;  4KVW A;  3WCG A;  3SDT A;  3B7L A;  4L2X F;  5ILJ A;  3OAB A;  3WCE A;  4DEM F;  3TFP A;  5ER8 A;  2AEK A;  4NUA A;  4OKZ A;  3VJE A;  3WCB A;  4NFI F;  1N22 A;  1V4K A;  3RMG A;  1UBX A;  4NG6 A;  4LLT A;  3ACY A;  3WEJ A;  5B02 A;  3N3D A;  2PS4 A;  3LGK A;  4N1Z F;  5IKA A;  1ZW5 A;  1HXG A;  3KRP A;  3RYW A;  3CKE A;  3P8L A;  4NKE A;  5ERN A;  3ASX A;  4LUU A;  1YV5 A;  2Z7I A;  5KSX F;  3UCA A;  4H5D F;  5CG6 A;  5HN9 A;  3ICM A;  4LXW A;  3VJB A;  2FOR A;  4OMG A;  1YHK A;  1VG2 A;  4F62 A;  5IK6 A;  2E93 A;  4JXY A;  2F8Z F;  3PH7 A;  4RXE A;  3WCM A;  4PVY F;  2ZEU A;  4JYX A;  3EGT A;  3TFV A;  4P0V A;  3DYG A;  1KIZ A;  2F94 F;  5B03 A;  2ZCQ A;  2E4O A;  2Z4X A;  5A0J A;  5AEL A;  3G4F A;  2RAH A;  3QQV A;  1WL1 A;  2Q80 A;  3ICK A;  4UMJ A;  1HXC A;  3PKO A;  4H5C F;  5ILH A;  3WCL A;  3SDV A;  4JXN A;  1HM7 A;  2OPN A;  5DIQ F;  4LFG A;  4KVD A;  2E8T A;  1YHM A;  5IL3 A;  3AQ0 A;  5B00 A;  3Q30 A;  2OA6 A;  4LTZ A; 
#chains in the Genus database with same CATH homology
 4FJQ A;  1WL2 A;  3V66 A;  3LLW A;  4LZ3 A;  3VJ9 A;  2Q9Y A;  4LZ0 A;  2ZCS A;  1UBY A;  3NPR A;  3DYF A;  3ACX A;  3P41 A;  4MC8 A;  3Q1O A;  2H8O A;  4DXJ A;  5E8L A;  3BNX A;  3NF2 A;  1N24 A;  2ZEV A;  4QPF A;  4F6V A;  2Z52 A;  5E8H A;  3TFN A;  3VJD A;  4QXS F;  5AHU B;  5DGM F;  2EWG A;  2F7M F;  3KRO B;  4LA5 A;  3LMD A;  4LOB A;  3APZ A;  4EA1 A;  3AQB B;  1EZF A;  5B0I A;  3ADZ A;  3WJO A;  2ZY1 A;  4LPG F;  2E8V A;  2P1C A;  1KIY A;  5DJP F;  4RXC A;  1JFA A;  3KRF B;  1WY0 A;  5B0J A;  2Z4W A;  3SDU A;  1WKZ A;  4KQ5 A;  4RNQ A;  3MZV A;  5DJV F;  3RYE A;  3N5H F;  5DGN F;  4F6X A;  4KVY A;  2VF6 A;  5E8K A;  1DI1 A;  4GA3 A;  4KQS A;  5AFX A;  4XQT F;  5IM1 A;  1V4J A;  3KRO A;  4E9Z A;  1YJ4 A;  2E95 A;  3EFQ A;  3ZL6 A;  1JFG A;  3P8R A;  3WCD A;  5ILD A;  5DHI A;  3WCF A;  3CC9 A;  4OGU A;  5B01 A;  5HNA A;  3WCI A;  3Q2Q A;  1WMW A;  1HX9 A;  4ZQ8 A;  2E8W A;  2J1O A;  4DWB A;  3WEH A;  4MC0 A;  5ILI A;  4OMH A;  3LJI A;  4P0W A;  5HN7 A;  3KRF A;  1VG3 A;  4HD1 A;  3WJK A;  2ZCO A;  4LA6 A;  3AE0 A;  4KQU A;  4MC3 A;  3N46 F;  1DGP A;  3IPI A;  4KWD A;  3TS7 A;  4KFA A;  3G4D A;  5HN8 A;  3AQC B;  5ILK A;  4PVX F;  4H5E F;  2AET A;  2J5C A;  3LEE A;  5C05 A;  5CG5 A;  1WL3 A;  3N3L F;  5JV0 F;  2O1O A;  3KRC B;  3LG5 A;  4XQS F;  3ACW A;  3N5J F;  3S9V A;  3ICZ A;  2Z4Z A;  4LZC A;  2AEL A;  4DHD A;  3N45 F;  3WCC A;  3N0G A;  4E9U A;  4NFK F;  5DGS F;  4KPD A;  3WCA A;  2J1P A;  4NFJ F;  1V4E A;  2E8X A;  5IK9 A;  2AZK A;  4JZX A;  2F92 F;  3Q2Z A;  5ERO A;  3N1W F;  4JZB A;  1N1Z A;  4DI5 A;  3LSN A;  2Q9Z A;  1PS1 A;  4NKF A;  3ZMC A;  2F89 F;  4KKM A;  2E91 A;  5B0L A;  3KRC A;  1YQ7 A;  5EAU A;  3TC1 A;  3N49 F;  3WC9 A;  1N23 A;  3KRA B;  5DZ2 A;  3VJA A;  4KK2 A;  3M00 A;  3LVS A;  5IK0 A;  5A0K A;  3OAC B;  4WK5 A;  3KB9 A;  4P0X A;  2FTZ A;  4RXD A;  5I1U A;  5EAT A;  1YYR A;  2OPM A;  4OKM A;  3LDW A;  3W7F A;  2I19 A;  3CP6 A;  1YYQ A;  3WCH A;  3WE9 A;  3ZCD A;  3PYA A;  5IKH A;  2ONG A;  5B0K A;  4LFV F;  1HXA A;  3S4J A;  3WEI A;  3KBK A;  5H9D A;  5ERM A;  5IMP A;  5ILY A;  1VG6 A;  4GP1 A;  4KPJ A;  1V4I A;  4FP4 A;  3M9U A;  3KRA A;  3LK5 A;  3WCJ A;  2PS6 A;  1VG7 A;  3VJ8 A;  2E90 A;  3OAC A;  3PDE A;  4LPH F;  3N6K F;  5IMI A;  1RQI A;  5JA0 F;  5JV2 F;  2AZL A;  4E1E A;  2PS7 A;  5ILZ A;  4KVI A;  2ONH A;  3MAV A;  5IVG A;  4DWG A;  3M0G A;  3VJC A;  3OYR A;  5A0I A;  5IN8 A;  3PYB A;  5B0M A;  1FPS A;  4LIX A;  1YHL A;  5JUZ F;  2E94 A;  4EA0 A;  2QIS A;  1UBW A;  2E8U A;  4RYP A;  4EA2 A;  1RTR A;  1RQJ A;  3V1X A;  2Z7H A;  3NPK A;  3IBA A;  3QKC A;  1N1B A;  3P5P A;  3M02 A;  3N0F A;  1WL0 A;  4XQR F;  3WSB A;  4LLS A;  3ZMB A;  4LTV A;  3N1V F;  3LZ9 A;  3WEK A;  1YYU A;  3SAE A;  2OGD A;  2AZJ A;  2Z78 A;  3LOM A;  3SDQ A;  3V1V A;  2PS5 A;  3BNY A;  1HM4 A;  5IMN A;  1N20 A;  3LGZ B;  3EZ3 A;  4GP2 A;  2DH4 A;  5EAS A;  3OAB B;  3WSA A;  2E92 A;  1VG4 A;  3DYH A;  5IL8 A;  3WEF A;  4DZW A;  1YYS A;  3RBM A;  3P5R A;  4JVJ F;  2Z4V A;  3ICN A;  2PS8 A;  3ZOU A;  3NRI A;  5DHK A;  1UBV A;  1YYT A;  4Q23 A;  3KRP B;  2Q58 A;  4GAX A;  2ZCR A;  4K10 A;  1N21 A;  3M01 A;  3ID0 A;  5DJR F;  4LFE A;  4RXA A;  1V4H A;  3WJN A;  2F9K F;  3WEG A;  5JV1 F;  2Z4Y A;  4N9U A;  4KUX A;  5AYP A;  3SDR A;  5DW7 A;  2F8C F;  2Z50 A;  4KVW A;  3WCG A;  3SDT A;  3B7L A;  4L2X F;  5ILJ A;  3OAB A;  3WCE A;  4DEM F;  3TFP A;  5ER8 A;  2AEK A;  4NUA A;  4OKZ A;  3VJE A;  3WCB A;  4NFI F;  1N22 A;  1V4K A;  3RMG A;  1UBX A;  4NG6 A;  4LLT A;  3ACY A;  3WEJ A;  5B02 A;  3N3D A;  2PS4 A;  3LGK A;  4N1Z F;  5IKA A;  1ZW5 A;  1HXG A;  3KRP A;  3RYW A;  3CKE A;  3P8L A;  4NKE A;  5ERN A;  3ASX A;  4LUU A;  1YV5 A;  2Z7I A;  5KSX F;  3UCA A;  4H5D F;  5CG6 A;  5HN9 A;  3ICM A;  4LXW A;  3VJB A;  2FOR A;  4OMG A;  1YHK A;  1VG2 A;  4F62 A;  5IK6 A;  2E93 A;  4JXY A;  2F8Z F;  3PH7 A;  4RXE A;  3WCM A;  4PVY F;  2ZEU A;  4JYX A;  3EGT A;  3TFV A;  4P0V A;  3DYG A;  1KIZ A;  2F94 F;  5B03 A;  2ZCQ A;  2E4O A;  2Z4X A;  5A0J A;  5AEL A;  3G4F A;  2RAH A;  3QQV A;  1WL1 A;  2Q80 A;  3ICK A;  4UMJ A;  1HXC A;  3PKO A;  4H5C F;  5ILH A;  3WCL A;  3SDV A;  4JXN A;  1HM7 A;  2OPN A;  5DIQ F;  4LFG A;  4KVD A;  2E8T A;  1YHM A;  5IL3 A;  3AQ0 A;  5B00 A;  3Q30 A;  2OA6 A;  4LTZ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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