4L19A

Matrix metalloproteinase-13 complexed with selective inhibitor compound q1
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
166
structure length
166
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Collagenase 3
publication title Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 48
structure length 166
sequence length 166
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2013-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4l19A00
2W12A 1BQOA 4L63A 2X3CA 3L0TA 5L7FA 2OW1A 1UTZA 1KUFA 1WNIA 3OHLA 1G12A 1XFZA 1L6JA 1G05A 1EUBA 1D5JA 2WO9A 3HDAP 3WV2A 1ZTQA 1KAPP 2X7MA 3LQ0A 2D1OA 1SRPA 4WK7A 2OW0A 1C8TA 1GKCA 4JIJA 4DF9A 4H30A 3F15A 5D1SA 1HY7A 4PKWA 2XS3A 1YP1A 3K7LA 5D2BA 4XCTA 966CA 4DPEA 1B8YA 4GR8A 4L19A 1JAOA 1GO7P 2OW2A 5D1UA 1GE5A 3OHOA 2O36A 1JH1A 1QUAA 1D8MA 4JPAA 2J83A 4J4MA 3DPEA 3E8RA 3LIRA 5BOYA 1PWQA 1PWWA 4AUOA 2V4BA 3HY9A 1UMTA 1SLMA 1QJJA 3VI1A 2OVXA 4XBHA 4PKSA 4XM8A 4GWMA 3B2ZA 5CXAA 2Y6CA 2AYKA 1B3DA 1ND1A 1BQQM 5BOTA 1OM8A 3Q2HA 1A85A 3UVCA 1ASTA 1GXDA 4I03A 1ZS0A 1PWPA 5I43A 4PKVA 4DV8A 1QIAA 1JIWP 5I12A 1K7QA 1Z3JA 4G0DA 3LILA 1MMQA 3USNA 3I7GA 3HY7A 1ATLA 1ZP5A 5L79A 3VTGA 3WV3A 1DTHA 3LE9A 3DL1A 1XUCA 3EDGA 3SHIA 3I7IA 4AYKA 3B92A 3DNGA 1UMSA 3TS4A 2DW2A 1SMPA 1UTTA 3F18A 3TSKA 4IN9A 1BIWA 1Y8JA 2SRTA 3Q2GA 1XURA 2YB9A 3EDZA 5I3MA 3LK8A 4ON1A 4WZVA 2QPJA 1PWUA 1D7XA 2FV5A 1IAGA 4I35A 1C7KA 1KUHA 1KUIA 5B5PA 2K9CA 4IJOA 1KUGA 4AXQA 3EDHA 3KEJA 4R3VA 4AIGA 4JP4A 2CKIA 3F17A 2OVZA 1BKCA 3LKAA 4H3XA 3ZVSA 3KECA 3MA2A 2MZIA 2ERPA 1MMBA 3LJZA 5I0LA 1SATA 3ZUKA 2FV9A 4GR3A 1XFUA 4EFSA 3G42A 4HMAA 1HOVA 1YOUA 1SLNA 2RJQA 4CTHA 1RMZA 3DPFA 1G4KA 3K7NA 4GQLA 4H2EA 3EDIA 5CUHA 1HFCA 1XFVA 3KRYA 2OI0A 1JANA 1MMPA 1Y93A 3AYKA 3LJTA 4GWNA 2OY2A 1BUVM 4PKTA 1BZSA 4FXQA 2KRJA 2YIGA 2Z2DA 1MNCA 2JIHA 1H71P 3O64A 1RM8A 4FVLA 2EROA 1G49A 1FM1A 3L0VA 4XM7A 1USNA 2JT5A 2K2GA 2E3XA 2HU6A 3V96B 3WV1A 4ZR5A 4Q1LA 1ZXCA 1IAEA 1S4BP 1FBLA 2O3EA 1JKYA 1GKDA 3HBVP 4PKUA 1KUKA 1OM7A 2USNA 3KHIA 1BM6A 2MZEA 2W13A 3HDBA 1CGEA 2W14A 3DSLA 1MMRA 1ZVXA 3N2VA 3KMEA 2DW0A 1YQYA 1CIZA 1OM6A 2L0RA 1EB6A 2MLRA 4G9LA 1I76A 1JIZA 1QICA 1IADA 1UEAA 1I1IP 4A7BA 3F1AA 1KBCA 3ELMA 2W15A 3HBUP 3LQBA 1CGLA 1DMTA 2D1NA 1SU3A 2CLTA 1Q3AA 2OZRA 1ROSA 830CA 4WKIA 4GF1A 4HX3A 1R1HA 3ZXHA 3F16A 4JQGA 2N8RA 1CXVA 4PKQA 1XFYA 4L6TA 1I73A 5B5OA 1QJIA 4WKEA 5I4OA 4FXYP 1JAQA 1R55A 3KEKA 1XFWA 3HB2P 1CK7A 3LGPA 2OW9A 3AYUA 4H1QA 1BUDA 4H76A 2DDFA 2W0DA 4FU4A 1JK3A 1IACA 3GBOA 1CQRA 3P24A 1IABA 3EHXA 3NX7A 2POJA 2J0TA 3P1VA 1ZXVA 5D7WA 3LEAA 2OY4A 3LUMA 1K7GA 2X3AA 4GUYA 1G9KA 2DDYA 2RJPA 5JMYA 3KWVC 1BKCE 1HTDA 1EAKA 1K7IA 3RTSA 5LABA 2I47A 3LMCA 1XFXA 1OO9A 3CKIA 1GE6A 3EWJA 2X3BA 3EHYA 1OS2A 1A86A 3TVCA 2A8HA 4QKZA 2MLSA 1OS9A 3KMCA 1PWVA 1C3IA 1JAPA 1BKCI 4ILWD 3TT4A 2WOAA 5D1TA 5H8XA 4WF6A 3G5CA 1IAAA 4JA1A 2ERQA 5BPAA 2JSDA 1JJ9A 2E2DA 2WO8A 3LIKA 2AIGP 5D3CA 1FLSA 2XS4A 4DD8A 1HFSA 3B8ZA 3BA0A 456CA 1YCMA 1O0QA 1AKLA 2Y6DA 3U1RA 3O2XA 1BSWA 1R1IA 1QIBA 2OXUA 3LUNA 3LJGA 2PJTA 1AF0A 4H82A 5CZMA 1Y0VA 1GE7A 1CGFA 3RTTA 1HV5A 4A3WA 1CAQA 1GO8P 4XM6A 4PKRA 3F19A 4GR0A 3N2UA 5I2ZA 2OXZA 2OXWA 3AIGA 1XUDA 1R54A 1O0TA 2JT6A 1J7NA 4H49A 4H84A 3HYGA 2DW1A 1R1JA 2TCLA 3DWBA 1D8FA 4IUWA 2JNPA 2MZHA 1OMJA 1AYKA
chains in the Genus database with same CATH superfamily
2W12A 1OZ9A 1BQOA 4L63A 2X3CA 3L0TA 5L7FA 2OW1A 1UTZA 1KUFA 1WNIA 3OHLA 1G12A 1XFZA 1L6JA 1G05A 1EUBA 1D5JA 2WO9A 3HDAP 3WV2A 1ZTQA 1KAPP 2X7MA 3LQ0A 2D1OA 1SRPA 4WK7A 2OW0A 1C8TA 1GKCA 4JIJA 4DF9A 4H30A 3F15A 5D1SA 1HY7A 4PKWA 2XS3A 1YP1A 3K7LA 5D2BA 4XCTA 966CA 4DPEA 1B8YA 4GR8A 4L19A 1JAOA 1GO7P 2OW2A 5D1UA 1GE5A 3OHOA 2O36A 1JH1A 1QUAA 1D8MA 4JPAA 2J83A 4J4MA 3DPEA 3E8RA 3LIRA 5BOYA 1PWQA 1PWWA 4AUOA 2V4BA 3HY9A 1UMTA 1SLMA 1QJJA 3VI1A 2OVXA 4XBHA 4PKSA 4XM8A 4GWMA 3B2ZA 5CXAA 2Y6CA 2AYKA 1B3DA 1ND1A 1BQQM 5BOTA 1OM8A 3Q2HA 1A85A 3UVCA 1ASTA 1GXDA 4I03A 1ZS0A 1PWPA 5I43A 4PKVA 4DV8A 1QIAA 2YUFA 1JIWP 5I12A 1K7QA 1Z3JA 4G0DA 3LILA 1MMQA 3USNA 3I7GA 3HY7A 1ATLA 1ZP5A 5L79A 3VTGA 3WV3A 1DTHA 3LE9A 3DL1A 1XUCA 3EDGA 3SHIA 3I7IA 4AYKA 3B92A 3DNGA 1UMSA 3TS4A 2DW2A 1SMPA 1UTTA 3F18A 3TSKA 4IN9A 1BIWA 1Y8JA 2SRTA 3Q2GA 1XURA 2YB9A 3EDZA 5I3MA 3LK8A 4ON1A 4WZVA 2QPJA 1PWUA 1D7XA 2FV5A 1IAGA 4I35A 1C7KA 1KUHA 1KUIA 5B5PA 2K9CA 4IJOA 1KUGA 4AXQA 3EDHA 3KEJA 4R3VA 4AIGA 4JP4A 2CKIA 3F17A 2OVZA 1BKCA 3LKAA 4H3XA 3ZVSA 3KECA 3MA2A 2MZIA 2ERPA 1MMBA 3LJZA 5I0LA 1SATA 3ZUKA 2FV9A 4GR3A 1XFUA 4EFSA 3G42A 4HMAA 1HOVA 1YOUA 1SLNA 2RJQA 4CTHA 1RMZA 3DPFA 1G4KA 3K7NA 4GQLA 4H2EA 3EDIA 5CUHA 1HFCA 1XFVA 3KRYA 2OI0A 1JANA 1MMPA 1Y93A 3AYKA 3LJTA 4GWNA 2OY2A 1BUVM 4PKTA 1BZSA 4FXQA 2KRJA 2YIGA 2Z2DA 1MNCA 2JIHA 1H71P 3O64A 1RM8A 4FVLA 2EROA 1G49A 1FM1A 3L0VA 4XM7A 1USNA 2JT5A 2K2GA 2E3XA 2HU6A 3V96B 3WV1A 4ZR5A 4Q1LA 1ZXCA 1IAEA 1XM5A 1S4BP 1FBLA 3DTIA 2O3EA 1JKYA 1GKDA 3HBVP 4PKUA 1KUKA 1OM7A 2USNA 3KHIA 1BM6A 2MZEA 2W13A 3HDBA 1CGEA 2W14A 3DTEA 3DSLA 1MMRA 1ZVXA 3N2VA 3KMEA 2DW0A 1YQYA 1CIZA 1OM6A 2L0RA 1EB6A 2MLRA 4G9LA 1I76A 1JIZA 1QICA 1IADA 1UEAA 1I1IP 1TVIA 4A7BA 3F1AA 1KBCA 3ELMA 2W15A 3HBUP 3LQBA 1CGLA 1DMTA 2D1NA 1SU3A 2CLTA 1Q3AA 2OZRA 1ROSA 830CA 4WKIA 4GF1A 4HX3A 1R1HA 3ZXHA 3F16A 4JQGA 2N8RA 1CXVA 4PKQA 1XFYA 4L6TA 1I73A 5B5OA 1QJIA 4WKEA 5I4OA 4FXYP 1JAQA 1R55A 3KEKA 1XFWA 3HB2P 1CK7A 3LGPA 2OW9A 3AYUA 4H1QA 1BUDA 4H76A 2DDFA 2W0DA 4FU4A 1JK3A 1IACA 3GBOA 1CQRA 3P24A 1IABA 3EHXA 3NX7A 2POJA 2J0TA 3P1VA 1ZXVA 5D7WA 3LEAA 2OY4A 3LUMA 1K7GA 2X3AA 4GUYA 1G9KA 2DDYA 2RJPA 5JMYA 3KWVC 1BKCE 1HTDA 1EAKA 1K7IA 3RTSA 5LABA 2I47A 3LMCA 1XFXA 1OO9A 3CKIA 1GE6A 3EWJA 2X3BA 3EHYA 1OS2A 1A86A 3TVCA 2A8HA 4QKZA 2MLSA 1OS9A 3KMCA 1PWVA 1C3IA 1JAPA 1BKCI 4ILWD 3TT4A 2WOAA 5D1TA 5H8XA 4WF6A 3G5CA 1IAAA 4JA1A 2ERQA 5BPAA 2JSDA 1JJ9A 2E2DA 2WO8A 3LIKA 3DTKA 2AIGP 5D3CA 1FLSA 2XS4A 4DD8A 1HFSA 3B8ZA 3BA0A 456CA 1YCMA 1O0QA 1AKLA 2Y6DA 3U1RA 3O2XA 1BSWA 1R1IA 1QIBA 2OXUA 3LUNA 1XAXA 3LJGA 2PJTA 1AF0A 4H82A 5CZMA 1Y0VA 1GE7A 1CGFA 3RTTA 1HV5A 4A3WA 1CAQA 4L7AA 1GO8P 4XM6A 4PKRA 3F19A 4GR0A 3N2UA 5I2ZA 2OXZA 2OXWA 3AIGA 1XUDA 1R54A 1O0TA 2JT6A 1J7NA 4H49A 4H84A 3HYGA 2DW1A 1R1JA 2TCLA 3DWBA 1D8FA 4IUWA 2JNPA 2MZHA 1OMJA 1AYKA
chains in the Genus database with same CATH topology
2W12A 1BQOA 4L63A 2X3CA 3L0TA 5L7FA 2OW1A 1UTZA 1KUFA 1WNIA 3OHLA 1G12A 1XFZA 1L6JA 1G05A 1EUBA 1D5JA 2WO9A 3HDAP 3WV2A 1ZTQA 1KAPP 2X7MA 3LQ0A 2D1OA 1SRPA 4WK7A 2OW0A 1C8TA 1GKCA 4JIJA 4DF9A 4H30A 3F15A 5D1SA 1HY7A 4PKWA 2XS3A 1YP1A 3K7LA 5D2BA 4XCTA 966CA 4DPEA 1B8YA 4GR8A 4L19A 1JAOA 1GO7P 2OW2A 5D1UA 1GE5A 3OHOA 2O36A 1JH1A 1QUAA 1D8MA 4JPAA 2J83A 4J4MA 3DPEA 3E8RA 3LIRA 5BOYA 1PWQA 1PWWA 4AUOA 2V4BA 3HY9A 1UMTA 1SLMA 1QJJA 3VI1A 2OVXA 4XBHA 4PKSA 4XM8A 4GWMA 3B2ZA 5CXAA 2Y6CA 2AYKA 1B3DA 1ND1A 1BQQM 5BOTA 1OM8A 3Q2HA 1A85A 3UVCA 1ASTA 1GXDA 4I03A 1ZS0A 1PWPA 5I43A 4PKVA 4DV8A 1QIAA 2YUFA 1JIWP 5I12A 1K7QA 1Z3JA 4G0DA 3LILA 1MMQA 3USNA 3I7GA 3HY7A 1ATLA 1ZP5A 5L79A 3VTGA 3WV3A 1DTHA 3LE9A 3DL1A 1XUCA 3EDGA 3SHIA 3I7IA 4AYKA 3B92A 3DNGA 1UMSA 3TS4A 2DW2A 1SMPA 1UTTA 3F18A 3TSKA 4IN9A 1BIWA 1Y8JA 2SRTA 3Q2GA 1XURA 2YB9A 3EDZA 5I3MA 3LK8A 4ON1A 4WZVA 2QPJA 1PWUA 1D7XA 2FV5A 1IAGA 4I35A 1C7KA 1KUHA 1KUIA 5B5PA 2K9CA 4IJOA 1KUGA 4AXQA 3EDHA 3KEJA 4R3VA 4AIGA 4JP4A 2CKIA 3F17A 2OVZA 1BKCA 3LKAA 4H3XA 3ZVSA 3KECA 3MA2A 2MZIA 2ERPA 1MMBA 3LJZA 5I0LA 1SATA 3ZUKA 2FV9A 4GR3A 1XFUA 4EFSA 3G42A 4HMAA 1HOVA 1YOUA 1SLNA 2RJQA 4CTHA 1RMZA 3DPFA 1G4KA 3K7NA 4GQLA 4H2EA 3EDIA 5CUHA 1HFCA 1XFVA 3KRYA 2OI0A 1JANA 1MMPA 1Y93A 3AYKA 3LJTA 4GWNA 2OY2A 1BUVM 4PKTA 1BZSA 4FXQA 2KRJA 2YIGA 2Z2DA 1MNCA 2JIHA 1H71P 3O64A 1RM8A 4FVLA 2EROA 1G49A 1FM1A 3L0VA 4XM7A 1USNA 2JT5A 2K2GA 2E3XA 2HU6A 3V96B 3WV1A 4ZR5A 4Q1LA 1ZXCA 1IAEA 1S4BP 1FBLA 3DTIA 2O3EA 1JKYA 1GKDA 3HBVP 4PKUA 1KUKA 1OM7A 2USNA 3KHIA 1BM6A 2MZEA 2W13A 3HDBA 1CGEA 2W14A 3DTEA 3DSLA 1MMRA 1ZVXA 3N2VA 3KMEA 2DW0A 1YQYA 1CIZA 1OM6A 2L0RA 1EB6A 2MLRA 4G9LA 1I76A 1JIZA 1QICA 1IADA 1UEAA 1I1IP 4A7BA 3F1AA 1KBCA 3ELMA 2W15A 3HBUP 3LQBA 1CGLA 1DMTA 2D1NA 1SU3A 2CLTA 1Q3AA 2OZRA 1ROSA 830CA 4WKIA 4GF1A 4HX3A 1R1HA 3ZXHA 3F16A 4JQGA 2N8RA 1CXVA 4PKQA 1XFYA 4L6TA 1I73A 5B5OA 1QJIA 4WKEA 5I4OA 4FXYP 1JAQA 1R55A 3KEKA 1XFWA 3HB2P 1CK7A 3LGPA 2OW9A 3AYUA 4H1QA 1BUDA 4H76A 2DDFA 2W0DA 4FU4A 1JK3A 1IACA 3GBOA 1CQRA 3P24A 1IABA 3EHXA 3NX7A 2POJA 2J0TA 3P1VA 1ZXVA 5D7WA 3LEAA 2OY4A 3LUMA 1K7GA 2X3AA 4GUYA 1G9KA 2DDYA 2RJPA 5JMYA 3KWVC 1BKCE 1HTDA 1EAKA 1K7IA 3RTSA 5LABA 2I47A 3LMCA 1XFXA 1OO9A 3CKIA 1GE6A 3EWJA 2X3BA 3EHYA 1OS2A 1A86A 3TVCA 2A8HA 4QKZA 2MLSA 1OS9A 3KMCA 1PWVA 1C3IA 1JAPA 1BKCI 4ILWD 3TT4A 2WOAA 5D1TA 5H8XA 4WF6A 3G5CA 1IAAA 4JA1A 2ERQA 5BPAA 2JSDA 1JJ9A 2E2DA 2WO8A 3LIKA 3DTKA 2AIGP 5D3CA 1FLSA 2XS4A 4DD8A 1HFSA 3B8ZA 3BA0A 456CA 1YCMA 1O0QA 1AKLA 2Y6DA 3U1RA 3O2XA 1BSWA 1R1IA 1QIBA 2OXUA 3LUNA 3LJGA 2PJTA 1AF0A 4H82A 5CZMA 1Y0VA 1GE7A 1CGFA 3RTTA 1HV5A 4A3WA 1CAQA 4L7AA 1GO8P 4XM6A 4PKRA 3F19A 4GR0A 3N2UA 5I2ZA 2OXZA 2OXWA 3AIGA 1XUDA 1R54A 1O0TA 2JT6A 1J7NA 4H49A 4H84A 3HYGA 2DW1A 1R1JA 2TCLA 3DWBA 1D8FA 4IUWA 2JNPA 2MZHA 1OMJA 1AYKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W12 A;  1BQO A;  4L63 A;  2X3C A;  3L0T A;  5L7F A;  2OW1 A;  1UTZ A;  1KUF A;  1WNI A;  3OHL A;  1G12 A;  1XFZ A;  1L6J A;  1G05 A;  1EUB A;  1D5J A;  2WO9 A;  3HDA P;  3WV2 A;  1ZTQ A;  1KAP P;  2X7M A;  3LQ0 A;  2D1O A;  1SRP A;  4WK7 A;  2OW0 A;  1C8T A;  1GKC A;  4JIJ A;  4DF9 A;  4H30 A;  3F15 A;  5D1S A;  1HY7 A;  4PKW A;  2XS3 A;  1YP1 A;  3K7L A;  5D2B A;  4XCT A;  966C A;  4DPE A;  1B8Y A;  4GR8 A;  4L19 A;  1JAO A;  1GO7 P;  2OW2 A;  5D1U A;  1GE5 A;  3OHO A;  2O36 A;  1JH1 A;  1QUA A;  1D8M A;  4JPA A;  2J83 A;  4J4M A;  3DPE A;  3E8R A;  3LIR A;  5BOY A;  1PWQ A;  1PWW A;  4AUO A;  2V4B A;  3HY9 A;  1UMT A;  1SLM A;  1QJJ A;  3VI1 A;  2OVX A;  4XBH A;  4PKS A;  4XM8 A;  4GWM A;  3B2Z A;  5CXA A;  2Y6C A;  2AYK A;  1B3D A;  1ND1 A;  1BQQ M;  5BOT A;  1OM8 A;  3Q2H A;  1A85 A;  3UVC A;  1AST A;  1GXD A;  4I03 A;  1ZS0 A;  1PWP A;  5I43 A;  4PKV A;  4DV8 A;  1QIA A;  1JIW P;  5I12 A;  1K7Q A;  1Z3J A;  4G0D A;  3LIL A;  1MMQ A;  3USN A;  3I7G A;  3HY7 A;  1ATL A;  1ZP5 A;  5L79 A;  3VTG A;  3WV3 A;  1DTH A;  3LE9 A;  3DL1 A;  1XUC A;  3EDG A;  3SHI A;  3I7I A;  4AYK A;  3B92 A;  3DNG A;  1UMS A;  3TS4 A;  2DW2 A;  1SMP A;  1UTT A;  3F18 A;  3TSK A;  4IN9 A;  1BIW A;  1Y8J A;  2SRT A;  3Q2G A;  1XUR A;  2YB9 A;  3EDZ A;  5I3M A;  3LK8 A;  4ON1 A;  4WZV A;  2QPJ A;  1PWU A;  1D7X A;  2FV5 A;  1IAG A;  4I35 A;  1C7K A;  1KUH A;  1KUI A;  5B5P A;  2K9C A;  4IJO A;  1KUG A;  4AXQ A;  3EDH A;  3KEJ A;  4R3V A;  4AIG A;  4JP4 A;  2CKI A;  3F17 A;  2OVZ A;  1BKC A;  3LKA A;  4H3X A;  3ZVS A;  3KEC A;  3MA2 A;  2MZI A;  2ERP A;  1MMB A;  3LJZ A;  5I0L A;  1SAT A;  3ZUK A;  2FV9 A;  4GR3 A;  1XFU A;  4EFS A;  3G42 A;  4HMA A;  1HOV A;  1YOU A;  1SLN A;  2RJQ A;  4CTH A;  1RMZ A;  3DPF A;  1G4K A;  3K7N A;  4GQL A;  4H2E A;  3EDI A;  5CUH A;  1HFC A;  1XFV A;  3KRY A;  2OI0 A;  1JAN A;  1MMP A;  1Y93 A;  3AYK A;  3LJT A;  4GWN A;  2OY2 A;  1BUV M;  4PKT A;  1BZS A;  4FXQ A;  2KRJ A;  2YIG A;  2Z2D A;  1MNC A;  2JIH A;  1H71 P;  3O64 A;  1RM8 A;  4FVL A;  2ERO A;  1G49 A;  1FM1 A;  3L0V A;  4XM7 A;  1USN A;  2JT5 A;  2K2G A;  2E3X A;  2HU6 A;  3V96 B;  3WV1 A;  4ZR5 A;  4Q1L A;  1ZXC A;  1IAE A;  1S4B P;  1FBL A;  2O3E A;  1JKY A;  1GKD A;  3HBV P;  4PKU A;  1KUK A;  1OM7 A;  2USN A;  3KHI A;  1BM6 A;  2MZE A;  2W13 A;  3HDB A;  1CGE A;  2W14 A;  3DSL A;  1MMR A;  1ZVX A;  3N2V A;  3KME A;  2DW0 A;  1YQY A;  1CIZ A;  1OM6 A;  2L0R A;  1EB6 A;  2MLR A;  4G9L A;  1I76 A;  1JIZ A;  1QIC A;  1IAD A;  1UEA A;  1I1I P;  4A7B A;  3F1A A;  1KBC A;  3ELM A;  2W15 A;  3HBU P;  3LQB A;  1CGL A;  1DMT A;  2D1N A;  1SU3 A;  2CLT A;  1Q3A A;  2OZR A;  1ROS A;  830C A;  4WKI A;  4GF1 A;  4HX3 A;  1R1H A;  3ZXH A;  3F16 A;  4JQG A;  2N8R A;  1CXV A;  4PKQ A;  1XFY A;  4L6T A;  1I73 A;  5B5O A;  1QJI A;  4WKE A;  5I4O A;  4FXY P;  1JAQ A;  1R55 A;  3KEK A;  1XFW A;  3HB2 P;  1CK7 A;  3LGP A;  2OW9 A;  3AYU A;  4H1Q A;  1BUD A;  4H76 A;  2DDF A;  2W0D A;  4FU4 A;  1JK3 A;  1IAC A;  3GBO A;  1CQR A;  3P24 A;  1IAB A;  3EHX A;  3NX7 A;  2POJ A;  2J0T A;  3P1V A;  1ZXV A;  5D7W A;  3LEA A;  2OY4 A;  3LUM A;  1K7G A;  2X3A A;  4GUY A;  1G9K A;  2DDY A;  2RJP A;  5JMY A;  3KWV C;  1BKC E;  1HTD A;  1EAK A;  1K7I A;  3RTS A;  5LAB A;  2I47 A;  3LMC A;  1XFX A;  1OO9 A;  3CKI A;  1GE6 A;  3EWJ A;  2X3B A;  3EHY A;  1OS2 A;  1A86 A;  3TVC A;  2A8H A;  4QKZ A;  2MLS A;  1OS9 A;  3KMC A;  1PWV A;  1C3I A;  1JAP A;  1BKC I;  4ILW D;  3TT4 A;  2WOA A;  5D1T A;  5H8X A;  4WF6 A;  3G5C A;  1IAA A;  4JA1 A;  2ERQ A;  5BPA A;  2JSD A;  1JJ9 A;  2E2D A;  2WO8 A;  3LIK A;  2AIG P;  5D3C A;  1FLS A;  2XS4 A;  4DD8 A;  1HFS A;  3B8Z A;  3BA0 A;  456C A;  1YCM A;  1O0Q A;  1AKL A;  2Y6D A;  3U1R A;  3O2X A;  1BSW A;  1R1I A;  1QIB A;  2OXU A;  3LUN A;  3LJG A;  2PJT A;  1AF0 A;  4H82 A;  5CZM A;  1Y0V A;  1GE7 A;  1CGF A;  3RTT A;  1HV5 A;  4A3W A;  1CAQ A;  1GO8 P;  4XM6 A;  4PKR A;  3F19 A;  4GR0 A;  3N2U A;  5I2Z A;  2OXZ A;  2OXW A;  3AIG A;  1XUD A;  1R54 A;  1O0T A;  2JT6 A;  1J7N A;  4H49 A;  4H84 A;  3HYG A;  2DW1 A;  1R1J A;  2TCL A;  3DWB A;  1D8F A;  4IUW A;  2JNP A;  2MZH A;  1OMJ A;  1AYK A; 
#chains in the Genus database with same CATH topology
 2W12 A;  1OZ9 A;  1BQO A;  4L63 A;  2X3C A;  3L0T A;  5L7F A;  2OW1 A;  1UTZ A;  1KUF A;  1WNI A;  3OHL A;  1G12 A;  1XFZ A;  1L6J A;  1G05 A;  1EUB A;  1D5J A;  2WO9 A;  3HDA P;  3WV2 A;  1ZTQ A;  1KAP P;  2X7M A;  3LQ0 A;  2D1O A;  1SRP A;  4WK7 A;  2OW0 A;  1C8T A;  1GKC A;  4JIJ A;  4DF9 A;  4H30 A;  3F15 A;  5D1S A;  1HY7 A;  4PKW A;  2XS3 A;  1YP1 A;  3K7L A;  5D2B A;  4XCT A;  966C A;  4DPE A;  1B8Y A;  4GR8 A;  4L19 A;  1JAO A;  1GO7 P;  2OW2 A;  5D1U A;  1GE5 A;  3OHO A;  2O36 A;  1JH1 A;  1QUA A;  1D8M A;  4JPA A;  2J83 A;  4J4M A;  3DPE A;  3E8R A;  3LIR A;  5BOY A;  1PWQ A;  1PWW A;  4AUO A;  2V4B A;  3HY9 A;  1UMT A;  1SLM A;  1QJJ A;  3VI1 A;  2OVX A;  4XBH A;  4PKS A;  4XM8 A;  4GWM A;  3B2Z A;  5CXA A;  2Y6C A;  2AYK A;  1B3D A;  1ND1 A;  1BQQ M;  5BOT A;  1OM8 A;  3Q2H A;  1A85 A;  3UVC A;  1AST A;  1GXD A;  4I03 A;  1ZS0 A;  1PWP A;  5I43 A;  4PKV A;  4DV8 A;  1QIA A;  2YUF A;  1JIW P;  5I12 A;  1K7Q A;  1Z3J A;  4G0D A;  3LIL A;  1MMQ A;  3USN A;  3I7G A;  3HY7 A;  1ATL A;  1ZP5 A;  5L79 A;  3VTG A;  3WV3 A;  1DTH A;  3LE9 A;  3DL1 A;  1XUC A;  3EDG A;  3SHI A;  3I7I A;  4AYK A;  3B92 A;  3DNG A;  1UMS A;  3TS4 A;  2DW2 A;  1SMP A;  1UTT A;  3F18 A;  3TSK A;  4IN9 A;  1BIW A;  1Y8J A;  2SRT A;  3Q2G A;  1XUR A;  2YB9 A;  3EDZ A;  5I3M A;  3LK8 A;  4ON1 A;  4WZV A;  2QPJ A;  1PWU A;  1D7X A;  2FV5 A;  1IAG A;  4I35 A;  1C7K A;  1KUH A;  1KUI A;  5B5P A;  2K9C A;  4IJO A;  1KUG A;  4AXQ A;  3EDH A;  3KEJ A;  4R3V A;  4AIG A;  4JP4 A;  2CKI A;  3F17 A;  2OVZ A;  1BKC A;  3LKA A;  4H3X A;  3ZVS A;  3KEC A;  3MA2 A;  2MZI A;  2ERP A;  1MMB A;  3LJZ A;  5I0L A;  1SAT A;  3ZUK A;  2FV9 A;  4GR3 A;  1XFU A;  4EFS A;  3G42 A;  4HMA A;  1HOV A;  1YOU A;  1SLN A;  2RJQ A;  4CTH A;  1RMZ A;  3DPF A;  1G4K A;  3K7N A;  4GQL A;  4H2E A;  3EDI A;  5CUH A;  1HFC A;  1XFV A;  3KRY A;  2OI0 A;  1JAN A;  1MMP A;  1Y93 A;  3AYK A;  3LJT A;  4GWN A;  2OY2 A;  1BUV M;  4PKT A;  1BZS A;  4FXQ A;  2KRJ A;  2YIG A;  2Z2D A;  1MNC A;  2JIH A;  1H71 P;  3O64 A;  1RM8 A;  4FVL A;  2ERO A;  1G49 A;  1FM1 A;  3L0V A;  4XM7 A;  1USN A;  2JT5 A;  2K2G A;  2E3X A;  2HU6 A;  3V96 B;  3WV1 A;  4ZR5 A;  4Q1L A;  1ZXC A;  1IAE A;  1XM5 A;  1S4B P;  1FBL A;  3DTI A;  2O3E A;  1JKY A;  1GKD A;  3HBV P;  4PKU A;  1KUK A;  1OM7 A;  2USN A;  3KHI A;  1BM6 A;  2MZE A;  2W13 A;  3HDB A;  1CGE A;  2W14 A;  3DTE A;  3DSL A;  1MMR A;  1ZVX A;  3N2V A;  3KME A;  2DW0 A;  1YQY A;  1CIZ A;  1OM6 A;  2L0R A;  1EB6 A;  2MLR A;  4G9L A;  1I76 A;  1JIZ A;  1QIC A;  1IAD A;  1UEA A;  1I1I P;  1TVI A;  4A7B A;  3F1A A;  1KBC A;  3ELM A;  2W15 A;  3HBU P;  3LQB A;  1CGL A;  1DMT A;  2D1N A;  1SU3 A;  2CLT A;  1Q3A A;  2OZR A;  1ROS A;  830C A;  4WKI A;  4GF1 A;  4HX3 A;  1R1H A;  3ZXH A;  3F16 A;  4JQG A;  2N8R A;  1CXV A;  4PKQ A;  1XFY A;  4L6T A;  1I73 A;  5B5O A;  1QJI A;  4WKE A;  5I4O A;  4FXY P;  1JAQ A;  1R55 A;  3KEK A;  1XFW A;  3HB2 P;  1CK7 A;  3LGP A;  2OW9 A;  3AYU A;  4H1Q A;  1BUD A;  4H76 A;  2DDF A;  2W0D A;  4FU4 A;  1JK3 A;  1IAC A;  3GBO A;  1CQR A;  3P24 A;  1IAB A;  3EHX A;  3NX7 A;  2POJ A;  2J0T A;  3P1V A;  1ZXV A;  5D7W A;  3LEA A;  2OY4 A;  3LUM A;  1K7G A;  2X3A A;  4GUY A;  1G9K A;  2DDY A;  2RJP A;  5JMY A;  3KWV C;  1BKC E;  1HTD A;  1EAK A;  1K7I A;  3RTS A;  5LAB A;  2I47 A;  3LMC A;  1XFX A;  1OO9 A;  3CKI A;  1GE6 A;  3EWJ A;  2X3B A;  3EHY A;  1OS2 A;  1A86 A;  3TVC A;  2A8H A;  4QKZ A;  2MLS A;  1OS9 A;  3KMC A;  1PWV A;  1C3I A;  1JAP A;  1BKC I;  4ILW D;  3TT4 A;  2WOA A;  5D1T A;  5H8X A;  4WF6 A;  3G5C A;  1IAA A;  4JA1 A;  2ERQ A;  5BPA A;  2JSD A;  1JJ9 A;  2E2D A;  2WO8 A;  3LIK A;  3DTK A;  2AIG P;  5D3C A;  1FLS A;  2XS4 A;  4DD8 A;  1HFS A;  3B8Z A;  3BA0 A;  456C A;  1YCM A;  1O0Q A;  1AKL A;  2Y6D A;  3U1R A;  3O2X A;  1BSW A;  1R1I A;  1QIB A;  2OXU A;  3LUN A;  1XAX A;  3LJG A;  2PJT A;  1AF0 A;  4H82 A;  5CZM A;  1Y0V A;  1GE7 A;  1CGF A;  3RTT A;  1HV5 A;  4A3W A;  1CAQ A;  4L7A A;  1GO8 P;  4XM6 A;  4PKR A;  3F19 A;  4GR0 A;  3N2U A;  5I2Z A;  2OXZ A;  2OXW A;  3AIG A;  1XUD A;  1R54 A;  1O0T A;  2JT6 A;  1J7N A;  4H49 A;  4H84 A;  3HYG A;  2DW1 A;  1R1J A;  2TCL A;  3DWB A;  1D8F A;  4IUW A;  2JNP A;  2MZH A;  1OMJ A;  1AYK A; 
#chains in the Genus database with same CATH homology
 2W12 A;  1BQO A;  4L63 A;  2X3C A;  3L0T A;  5L7F A;  2OW1 A;  1UTZ A;  1KUF A;  1WNI A;  3OHL A;  1G12 A;  1XFZ A;  1L6J A;  1G05 A;  1EUB A;  1D5J A;  2WO9 A;  3HDA P;  3WV2 A;  1ZTQ A;  1KAP P;  2X7M A;  3LQ0 A;  2D1O A;  1SRP A;  4WK7 A;  2OW0 A;  1C8T A;  1GKC A;  4JIJ A;  4DF9 A;  4H30 A;  3F15 A;  5D1S A;  1HY7 A;  4PKW A;  2XS3 A;  1YP1 A;  3K7L A;  5D2B A;  4XCT A;  966C A;  4DPE A;  1B8Y A;  4GR8 A;  4L19 A;  1JAO A;  1GO7 P;  2OW2 A;  5D1U A;  1GE5 A;  3OHO A;  2O36 A;  1JH1 A;  1QUA A;  1D8M A;  4JPA A;  2J83 A;  4J4M A;  3DPE A;  3E8R A;  3LIR A;  5BOY A;  1PWQ A;  1PWW A;  4AUO A;  2V4B A;  3HY9 A;  1UMT A;  1SLM A;  1QJJ A;  3VI1 A;  2OVX A;  4XBH A;  4PKS A;  4XM8 A;  4GWM A;  3B2Z A;  5CXA A;  2Y6C A;  2AYK A;  1B3D A;  1ND1 A;  1BQQ M;  5BOT A;  1OM8 A;  3Q2H A;  1A85 A;  3UVC A;  1AST A;  1GXD A;  4I03 A;  1ZS0 A;  1PWP A;  5I43 A;  4PKV A;  4DV8 A;  1QIA A;  2YUF A;  1JIW P;  5I12 A;  1K7Q A;  1Z3J A;  4G0D A;  3LIL A;  1MMQ A;  3USN A;  3I7G A;  3HY7 A;  1ATL A;  1ZP5 A;  5L79 A;  3VTG A;  3WV3 A;  1DTH A;  3LE9 A;  3DL1 A;  1XUC A;  3EDG A;  3SHI A;  3I7I A;  4AYK A;  3B92 A;  3DNG A;  1UMS A;  3TS4 A;  2DW2 A;  1SMP A;  1UTT A;  3F18 A;  3TSK A;  4IN9 A;  1BIW A;  1Y8J A;  2SRT A;  3Q2G A;  1XUR A;  2YB9 A;  3EDZ A;  5I3M A;  3LK8 A;  4ON1 A;  4WZV A;  2QPJ A;  1PWU A;  1D7X A;  2FV5 A;  1IAG A;  4I35 A;  1C7K A;  1KUH A;  1KUI A;  5B5P A;  2K9C A;  4IJO A;  1KUG A;  4AXQ A;  3EDH A;  3KEJ A;  4R3V A;  4AIG A;  4JP4 A;  2CKI A;  3F17 A;  2OVZ A;  1BKC A;  3LKA A;  4H3X A;  3ZVS A;  3KEC A;  3MA2 A;  2MZI A;  2ERP A;  1MMB A;  3LJZ A;  5I0L A;  1SAT A;  3ZUK A;  2FV9 A;  4GR3 A;  1XFU A;  4EFS A;  3G42 A;  4HMA A;  1HOV A;  1YOU A;  1SLN A;  2RJQ A;  4CTH A;  1RMZ A;  3DPF A;  1G4K A;  3K7N A;  4GQL A;  4H2E A;  3EDI A;  5CUH A;  1HFC A;  1XFV A;  3KRY A;  2OI0 A;  1JAN A;  1MMP A;  1Y93 A;  3AYK A;  3LJT A;  4GWN A;  2OY2 A;  1BUV M;  4PKT A;  1BZS A;  4FXQ A;  2KRJ A;  2YIG A;  2Z2D A;  1MNC A;  2JIH A;  1H71 P;  3O64 A;  1RM8 A;  4FVL A;  2ERO A;  1G49 A;  1FM1 A;  3L0V A;  4XM7 A;  1USN A;  2JT5 A;  2K2G A;  2E3X A;  2HU6 A;  3V96 B;  3WV1 A;  4ZR5 A;  4Q1L A;  1ZXC A;  1IAE A;  1S4B P;  1FBL A;  3DTI A;  2O3E A;  1JKY A;  1GKD A;  3HBV P;  4PKU A;  1KUK A;  1OM7 A;  2USN A;  3KHI A;  1BM6 A;  2MZE A;  2W13 A;  3HDB A;  1CGE A;  2W14 A;  3DTE A;  3DSL A;  1MMR A;  1ZVX A;  3N2V A;  3KME A;  2DW0 A;  1YQY A;  1CIZ A;  1OM6 A;  2L0R A;  1EB6 A;  2MLR A;  4G9L A;  1I76 A;  1JIZ A;  1QIC A;  1IAD A;  1UEA A;  1I1I P;  4A7B A;  3F1A A;  1KBC A;  3ELM A;  2W15 A;  3HBU P;  3LQB A;  1CGL A;  1DMT A;  2D1N A;  1SU3 A;  2CLT A;  1Q3A A;  2OZR A;  1ROS A;  830C A;  4WKI A;  4GF1 A;  4HX3 A;  1R1H A;  3ZXH A;  3F16 A;  4JQG A;  2N8R A;  1CXV A;  4PKQ A;  1XFY A;  4L6T A;  1I73 A;  5B5O A;  1QJI A;  4WKE A;  5I4O A;  4FXY P;  1JAQ A;  1R55 A;  3KEK A;  1XFW A;  3HB2 P;  1CK7 A;  3LGP A;  2OW9 A;  3AYU A;  4H1Q A;  1BUD A;  4H76 A;  2DDF A;  2W0D A;  4FU4 A;  1JK3 A;  1IAC A;  3GBO A;  1CQR A;  3P24 A;  1IAB A;  3EHX A;  3NX7 A;  2POJ A;  2J0T A;  3P1V A;  1ZXV A;  5D7W A;  3LEA A;  2OY4 A;  3LUM A;  1K7G A;  2X3A A;  4GUY A;  1G9K A;  2DDY A;  2RJP A;  5JMY A;  3KWV C;  1BKC E;  1HTD A;  1EAK A;  1K7I A;  3RTS A;  5LAB A;  2I47 A;  3LMC A;  1XFX A;  1OO9 A;  3CKI A;  1GE6 A;  3EWJ A;  2X3B A;  3EHY A;  1OS2 A;  1A86 A;  3TVC A;  2A8H A;  4QKZ A;  2MLS A;  1OS9 A;  3KMC A;  1PWV A;  1C3I A;  1JAP A;  1BKC I;  4ILW D;  3TT4 A;  2WOA A;  5D1T A;  5H8X A;  4WF6 A;  3G5C A;  1IAA A;  4JA1 A;  2ERQ A;  5BPA A;  2JSD A;  1JJ9 A;  2E2D A;  2WO8 A;  3LIK A;  3DTK A;  2AIG P;  5D3C A;  1FLS A;  2XS4 A;  4DD8 A;  1HFS A;  3B8Z A;  3BA0 A;  456C A;  1YCM A;  1O0Q A;  1AKL A;  2Y6D A;  3U1R A;  3O2X A;  1BSW A;  1R1I A;  1QIB A;  2OXU A;  3LUN A;  3LJG A;  2PJT A;  1AF0 A;  4H82 A;  5CZM A;  1Y0V A;  1GE7 A;  1CGF A;  3RTT A;  1HV5 A;  4A3W A;  1CAQ A;  4L7A A;  1GO8 P;  4XM6 A;  4PKR A;  3F19 A;  4GR0 A;  3N2U A;  5I2Z A;  2OXZ A;  2OXW A;  3AIG A;  1XUD A;  1R54 A;  1O0T A;  2JT6 A;  1J7N A;  4H49 A;  4H84 A;  3HYG A;  2DW1 A;  1R1J A;  2TCL A;  3DWB A;  1D8F A;  4IUW A;  2JNP A;  2MZH A;  1OMJ A;  1AYK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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