4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Transferase
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
2I6DA 4X3MA 2V3KA 4KGNA 2V3JA 1NS5A 5CO4A 1J85A 4YQ2A 4MCDA 1VHKA 3KTYA 4YVGA 3BBDA 4RG1A 4YQKA 1MXIA 4H3ZA 3NK6A 1ZJRA 1V2XA 4JALA 3IC6A 4CNGA 4KDZA 1O6DA 2YY8A 4YPXA 1OY5A 5GMCA 4FAKA 4YQ6A 4MCCA 4YQ8A 4YQDA 5D9FA 4E8BA 1K3RA 3GYQA 3N4KA 2HA8A 4H3YA 4YQOA 1UAMA 4YQ1A 2CX8A 1GZ0A 1X7OA 4YQLA 4YQ7A 4J3CA 4YQBA 4JAKA 4YQ3A 4YQ0A 1UAJA 4PZKA 4YQQA 3O7BA 1UALA 3ONPA 5FAIA 4CNDA 4YVHA 1VHYA 3KW2A 4YQIA 2EGVA 5GM8A 1IPAA 1Z85A 4YQCA 1TO0A 3BBHA 4YVJA 3DCMX 5GMBA 3QUVA 4YVIA 4YQJA 4MCBA 2NWAA 2QWVA 3KNUA 3AIAA 4YPYA 4YQ9A 4YQGA 4YPZA 1V6ZA 2O3AA 4YQ4A 4YQNA 4XBOA 3BBEA 3ILKA 1P9PA 4YQPA 4IG6A 3IEFA 4YQTA 4CNFA 3E5YA 3L8UA 3OIIA 4YQRA 4CNEA 1VH0A 4YQSA 4YQAA 2EGWA 1NXZA 3OIJA 4YPWA 2Z0YA 2QMMA 3AI9X 4X3LA 4YVKA 3AXZA 3KY7A 3OINA 3NK7A 1UAKA 1X7PA 4L69A 4YQ5A 3N4JA
chains in the Genus database with same CATH superfamily
2I6DA 2GAEA 1O0BA 4X3MA 2V3KA 4KGNA 3PIPS 1NS5A 2V3JA 5CO4A 1J85A 4WFBS 4IO9S 4YQ2A 4MCDA 1QRTA 1VHKA 3KTYA 2RE8A 1GTRA 5BNZA 4YVGA 3BBDA 4RG1A 1QRSA 2PI8A 4YQKA 1MXIA 1ZJWA 4H3ZA 4H4KA 1ZJRA 3NK6A 1V2XA 4JALA 2ZJQS 3IC6A 4CNGA 5DM6S 4KDZA 1O6DA 2YY8A 4YPXA 5DM7S 2ZJRS 1OY5A 3W2WB 5JVGS 2HZ7A 5GMCA 4FAKA 1O0CA 4WF9S 4YQ6A 1DFUP 4MCCA 4YQ8A 4YQDA 4WFNS 4UY88 4E8BA 5D9FA 3DLLS 4IOAS 1K3RA 3GYQA 3N4KA 2HA8A 4H3YA 4YQOA 1UAMA 4YQ1A 4WFAS 2CX8A 1GZ0A 1X7OA 4YQLA 1EUYA 5HL7S 4YQ7A 4J3CA 4YQBA 4JAKA 4YQ3A 4YQ0A 3AIIA 1UAJA 4PZKA 4YQQA 3O7BA 1UALA 5JVHS 3ONPA 5FAIA 4CNDA 4YVHA 1VHYA 3KW2A 4YQIA 2EGVA 3W2VB 5GM8A 1IPAA 5IZNA 5GADW 1FEUA 1Z85A 3J7ZV 4YQCA 1TO0A 3BBHA 2PNWA 5GAGW 3DCMX 4JWFA 5GMBA 3QUVA 4YVJA 4YVIA 4YQJA 2RD2A 4MCBA 2NWAA 2QWVA 4FMWA 3CF5S 3KNUA 1D6KA 3AIAA 4JWGA 4V194 4YPYA 4YPZA 1V6ZA 2O3AA 4YQ9A 4YQGA 1B75A 4YQ4A 4YQNA 3CZBA 4XBOA 3BBEA 4IOCS 5GAHW 3ILKA 4JXXA 1P9PA 4YQPA 4WCES 2PJJA 4IG6A 2AE0X 3IEFA 4YQTA 4CNFA 1QTQA 3E5YA 3L8UA 3OIIA 1QRUA 4YQRA 1UDXA 1GTSA 2G6GA 4CNEA 5GAEW 1EUQA 3X1LB 4P2BA 1VH0A 3PIOS 4H3SA 4JYZA 1EXDA 4JXZA 4YQSA 4YQAA 2EGWA 4JWJA 2ZJPS 1NXZA 4JWHA 2PICA 3OIJA 4YPWA 2Z0YA 2QMMA 3AI9X 2G5DA 4X3LA 3AXZA 4YVKA 3KY7A 3OINA 1NYLA 4U67S 3NK7A 1UAKA 1X7PA 4L69A 4YQ5A 3N4JA
chains in the Genus database with same CATH topology
2I6DA 4X3MA 2V3KA 4KGNA 2V3JA 1NS5A 5CO4A 1J85A 4YQ2A 4MCDA 1VHKA 3KTYA 4YVGA 3BBDA 4RG1A 4YQKA 1MXIA 4H3ZA 3NK6A 1ZJRA 1V2XA 4JALA 3IC6A 4CNGA 4KDZA 1O6DA 2YY8A 4YPXA 1OY5A 5GMCA 4FAKA 4YQ6A 4MCCA 4YQ8A 4YQDA 5D9FA 4E8BA 1K3RA 3GYQA 3N4KA 2HA8A 4H3YA 4YQOA 1UAMA 4YQ1A 2CX8A 1GZ0A 1X7OA 4YQLA 4YQ7A 4J3CA 4YQBA 4JAKA 4YQ3A 4YQ0A 1UAJA 4PZKA 4YQQA 3O7BA 1UALA 3ONPA 5FAIA 4CNDA 4YVHA 1VHYA 3KW2A 4YQIA 2EGVA 5GM8A 1IPAA 1Z85A 4YQCA 1TO0A 3BBHA 4YVJA 3DCMX 4JWFA 5GMBA 3QUVA 4YVIA 4YQJA 4MCBA 2NWAA 2QWVA 4FMWA 3KNUA 3AIAA 4JWGA 4YPYA 4YQ9A 4YPZA 1V6ZA 2O3AA 4YQGA 4YQ4A 4YQNA 4XBOA 3BBEA 3ILKA 1P9PA 4YQPA 4IG6A 3IEFA 4YQTA 4CNFA 3E5YA 3L8UA 3OIIA 4YQRA 4CNEA 1VH0A 4YQSA 4YQAA 2EGWA 4JWJA 4JWHA 1NXZA 3OIJA 4YPWA 2Z0YA 2QMMA 3AI9X 4X3LA 4YVKA 3AXZA 3KY7A 3OINA 3NK7A 1UAKA 1X7PA 4L69A 4YQ5A 3N4JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I6D A;  4X3M A;  2V3K A;  4KGN A;  2V3J A;  1NS5 A;  5CO4 A;  1J85 A;  4YQ2 A;  4MCD A;  1VHK A;  3KTY A;  4YVG A;  3BBD A;  4RG1 A;  4YQK A;  1MXI A;  4H3Z A;  3NK6 A;  1ZJR A;  1V2X A;  4JAL A;  3IC6 A;  4CNG A;  4KDZ A;  1O6D A;  2YY8 A;  4YPX A;  1OY5 A;  5GMC A;  4FAK A;  4YQ6 A;  4MCC A;  4YQ8 A;  4YQD A;  5D9F A;  4E8B A;  1K3R A;  3GYQ A;  3N4K A;  2HA8 A;  4H3Y A;  4YQO A;  1UAM A;  4YQ1 A;  2CX8 A;  1GZ0 A;  1X7O A;  4YQL A;  4YQ7 A;  4J3C A;  4YQB A;  4JAK A;  4YQ3 A;  4YQ0 A;  1UAJ A;  4PZK A;  4YQQ A;  3O7B A;  1UAL A;  3ONP A;  5FAI A;  4CND A;  4YVH A;  1VHY A;  3KW2 A;  4YQI A;  2EGV A;  5GM8 A;  1IPA A;  1Z85 A;  4YQC A;  1TO0 A;  3BBH A;  4YVJ A;  3DCM X;  5GMB A;  3QUV A;  4YVI A;  4YQJ A;  4MCB A;  2NWA A;  2QWV A;  3KNU A;  3AIA A;  4YPY A;  4YQ9 A;  4YQG A;  4YPZ A;  1V6Z A;  2O3A A;  4YQ4 A;  4YQN A;  4XBO A;  3BBE A;  3ILK A;  1P9P A;  4YQP A;  4IG6 A;  3IEF A;  4YQT A;  4CNF A;  3E5Y A;  3L8U A;  3OII A;  4YQR A;  4CNE A;  1VH0 A;  4YQS A;  4YQA A;  2EGW A;  1NXZ A;  3OIJ A;  4YPW A;  2Z0Y A;  2QMM A;  3AI9 X;  4X3L A;  4YVK A;  3AXZ A;  3KY7 A;  3OIN A;  3NK7 A;  1UAK A;  1X7P A;  4L69 A;  4YQ5 A;  3N4J A; 
#chains in the Genus database with same CATH topology
 2I6D A;  2GAE A;  1O0B A;  4X3M A;  2V3K A;  4KGN A;  3PIP S;  1NS5 A;  2V3J A;  5CO4 A;  1J85 A;  4WFB S;  4IO9 S;  4YQ2 A;  4MCD A;  1QRT A;  1VHK A;  3KTY A;  2RE8 A;  1GTR A;  5BNZ A;  4YVG A;  3BBD A;  4RG1 A;  1QRS A;  2PI8 A;  4YQK A;  1MXI A;  1ZJW A;  4H3Z A;  4H4K A;  1ZJR A;  3NK6 A;  1V2X A;  4JAL A;  2ZJQ S;  3IC6 A;  4CNG A;  5DM6 S;  4KDZ A;  1O6D A;  2YY8 A;  4YPX A;  5DM7 S;  2ZJR S;  1OY5 A;  3W2W B;  5JVG S;  2HZ7 A;  5GMC A;  4FAK A;  1O0C A;  4WF9 S;  4YQ6 A;  1DFU P;  4MCC A;  4YQ8 A;  4YQD A;  4WFN S;  4UY8 8;  4E8B A;  5D9F A;  3DLL S;  4IOA S;  1K3R A;  3GYQ A;  3N4K A;  2HA8 A;  4H3Y A;  4YQO A;  1UAM A;  4YQ1 A;  4WFA S;  2CX8 A;  1GZ0 A;  1X7O A;  4YQL A;  1EUY A;  5HL7 S;  4YQ7 A;  4J3C A;  4YQB A;  4JAK A;  4YQ3 A;  4YQ0 A;  3AII A;  1UAJ A;  4PZK A;  4YQQ A;  3O7B A;  1UAL A;  5JVH S;  3ONP A;  5FAI A;  4CND A;  4YVH A;  1VHY A;  3KW2 A;  4YQI A;  2EGV A;  3W2V B;  5GM8 A;  1IPA A;  5IZN A;  5GAD W;  1FEU A;  1Z85 A;  3J7Z V;  4YQC A;  1TO0 A;  3BBH A;  2PNW A;  5GAG W;  3DCM X;  4JWF A;  5GMB A;  3QUV A;  4YVJ A;  4YVI A;  4YQJ A;  2RD2 A;  4MCB A;  2NWA A;  2QWV A;  4FMW A;  3CF5 S;  3KNU A;  1D6K A;  3AIA A;  4JWG A;  4V19 4;  4YPY A;  4YPZ A;  1V6Z A;  2O3A A;  4YQ9 A;  4YQG A;  1B75 A;  4YQ4 A;  4YQN A;  3CZB A;  4XBO A;  3BBE A;  4IOC S;  5GAH W;  3ILK A;  4JXX A;  1P9P A;  4YQP A;  4WCE S;  2PJJ A;  4IG6 A;  2AE0 X;  3IEF A;  4YQT A;  4CNF A;  1QTQ A;  3E5Y A;  3L8U A;  3OII A;  1QRU A;  4YQR A;  1UDX A;  1GTS A;  2G6G A;  4CNE A;  5GAE W;  1EUQ A;  3X1L B;  4P2B A;  1VH0 A;  3PIO S;  4H3S A;  4JYZ A;  1EXD A;  4JXZ A;  4YQS A;  4YQA A;  2EGW A;  4JWJ A;  2ZJP S;  1NXZ A;  4JWH A;  2PIC A;  3OIJ A;  4YPW A;  2Z0Y A;  2QMM A;  3AI9 X;  2G5D A;  4X3L A;  3AXZ A;  4YVK A;  3KY7 A;  3OIN A;  1NYL A;  4U67 S;  3NK7 A;  1UAK A;  1X7P A;  4L69 A;  4YQ5 A;  3N4J A; 
#chains in the Genus database with same CATH homology
 2I6D A;  4X3M A;  2V3K A;  4KGN A;  2V3J A;  1NS5 A;  5CO4 A;  1J85 A;  4YQ2 A;  4MCD A;  1VHK A;  3KTY A;  4YVG A;  3BBD A;  4RG1 A;  4YQK A;  1MXI A;  4H3Z A;  3NK6 A;  1ZJR A;  1V2X A;  4JAL A;  3IC6 A;  4CNG A;  4KDZ A;  1O6D A;  2YY8 A;  4YPX A;  1OY5 A;  5GMC A;  4FAK A;  4YQ6 A;  4MCC A;  4YQ8 A;  4YQD A;  5D9F A;  4E8B A;  1K3R A;  3GYQ A;  3N4K A;  2HA8 A;  4H3Y A;  4YQO A;  1UAM A;  4YQ1 A;  2CX8 A;  1GZ0 A;  1X7O A;  4YQL A;  4YQ7 A;  4J3C A;  4YQB A;  4JAK A;  4YQ3 A;  4YQ0 A;  1UAJ A;  4PZK A;  4YQQ A;  3O7B A;  1UAL A;  3ONP A;  5FAI A;  4CND A;  4YVH A;  1VHY A;  3KW2 A;  4YQI A;  2EGV A;  5GM8 A;  1IPA A;  1Z85 A;  4YQC A;  1TO0 A;  3BBH A;  4YVJ A;  3DCM X;  4JWF A;  5GMB A;  3QUV A;  4YVI A;  4YQJ A;  4MCB A;  2NWA A;  2QWV A;  4FMW A;  3KNU A;  3AIA A;  4JWG A;  4YPY A;  4YQ9 A;  4YPZ A;  1V6Z A;  2O3A A;  4YQG A;  4YQ4 A;  4YQN A;  4XBO A;  3BBE A;  3ILK A;  1P9P A;  4YQP A;  4IG6 A;  3IEF A;  4YQT A;  4CNF A;  3E5Y A;  3L8U A;  3OII A;  4YQR A;  4CNE A;  1VH0 A;  4YQS A;  4YQA A;  2EGW A;  4JWJ A;  4JWH A;  1NXZ A;  3OIJ A;  4YPW A;  2Z0Y A;  2QMM A;  3AI9 X;  4X3L A;  4YVK A;  3AXZ A;  3KY7 A;  3OIN A;  3NK7 A;  1UAK A;  1X7P A;  4L69 A;  4YQ5 A;  3N4J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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