4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Transferase
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
1X7OA 1Z85A 3BBEA 4RG1A 4KDZA 4CNEA 1X7PA 4YQ3A 3KTYA 3L8UA 4YQBA 1VHYA 4YPYA 4YVIA 2V3JA 4YQLA 1GZ0A 4YQPA 4XBOA 3AXZA 3OINA 4YQIA 2I6DA 1P9PA 2EGWA 4JALA 3N4KA 3NK7A 2QMMA 1IPAA 5CO4A 4FAKA 4YQ5A 1UAJA 2V3KA 4YPXA 4KGNA 5D9FA 4H3ZA 4YQSA 3IC6A 4YPWA 4H3YA 4YQ1A 4YQRA 3ONPA 3BBDA 5GMCA 1J85A 4E8BA 4X3LA 2YY8A 2EGVA 1VHKA 3KW2A 1UAKA 4YQTA 4YQGA 3N4JA 2QWVA 1NXZA 4CNGA 4YQ7A 3ILKA 4JAKA 3E5YA 4CNFA 4YVGA 1UALA 4YQ0A 1MXIA 3GYQA 4YQ2A 4CNDA 3KNUA 4YQDA 4YQAA 1K3RA 4PZKA 5GM8A 3DCMX 2HA8A 4YQ6A 4L69A 4YPZA 1TO0A 4IG6A 1VH0A 4YQKA 4YVKA 3OIJA 4YQ4A 3NK6A 4YQ9A 2Z0YA 4X3MA 5FAIA 1V2XA 4YQOA 2O3AA 3AI9X 5GMBA 1ZJRA 4YVHA 1V6ZA 2NWAA 3IEFA 4YQCA 1O6DA 3QUVA 4YQQA 4YQNA 3BBHA 4MCCA 4YVJA 1OY5A 4MCDA 3OIIA 4YQJA 3AIAA 3KY7A 3O7BA 2CX8A 1NS5A 4J3CA 4MCBA 4YQ8A 1UAMA
chains in the Genus database with same CATH superfamily
1X7OA 3X1LB 4IOAS 4IOCS 1UDXA 1Z85A 3BBEA 4RG1A 3CZBA 4KDZA 4CNEA 1X7PA 1QTQA 5JVHS 2HZ7A 5DM7S 4YQ3A 4WFNS 5JVGS 3KTYA 2ZJQS 1O0BA 3L8UA 4YQBA 1VHYA 4YPYA 4YVIA 5IZNA 1FEUA 3PIOS 2V3JA 4YQLA 4IO9S 2RD2A 4WCES 1GZ0A 4YQPA 4H4KA 4JWFA 4XBOA 3AXZA 3OINA 4YQIA 2I6DA 1P9PA 2EGWA 4JALA 2QMMA 1IPAA 3N4KA 3NK7A 5CO4A 4FAKA 4YQ5A 1UAJA 2V3KA 4YPXA 4KGNA 5D9FA 3W2WB 4H3ZA 4YQSA 2AE0X 3PIPS 4JXXA 4H3SA 5GAEW 3IC6A 3W2VB 4YPWA 5HL7S 2PNWA 3AIIA 1EUYA 4H3YA 2PJJA 5GAGW 4YQ1A 2ZJRS 1D6KA 4YQRA 3ONPA 3BBDA 5GMCA 1EUQA 1J85A 2RE8A 4E8BA 4X3LA 2YY8A 2EGVA 1NYLA 1VHKA 3KW2A 2GAEA 2ZJPS 4JWJA 4WFAS 1UAKA 4YQTA 4YQGA 3N4JA 5GADW 2PI8A 2QWVA 1QRTA 4WF9S 1NXZA 5GAHW 4CNGA 4YQ7A 3ILKA 4JAKA 3E5YA 4CNFA 3J7ZV 1UALA 4YVGA 4YQ0A 1MXIA 1DFUP 3GYQA 1QRUA 4YQ2A 4CNDA 3KNUA 4YQDA 4YQAA 1K3RA 1GTRA 2PICA 4JWHA 4PZKA 3DCMX 5GM8A 2HA8A 1EXDA 4YQ6A 4WFBS 4L69A 4YPZA 4V194 1TO0A 4IG6A 1VH0A 4P2BA 4YQKA 4FMWA 3DLLS 4YQ4A 3NK6A 4YVKA 4YQ9A 3OIJA 2Z0YA 4X3MA 5FAIA 1V2XA 4YQOA 4JXZA 2G5DA 4JWGA 2O3AA 1B75A 3AI9X 5GMBA 5BNZA 1ZJRA 5DM6S 4UY88 1QRSA 1ZJWA 4YVHA 1V6ZA 2NWAA 3IEFA 4YQCA 1O6DA 3QUVA 1GTSA 4JYZA 4YQQA 4U67S 2G6GA 3CF5S 4YQNA 3BBHA 4MCCA 4YVJA 1OY5A 4MCDA 3OIIA 4YQJA 1O0CA 3AIAA 3KY7A 3O7BA 2CX8A 1NS5A 4J3CA 4MCBA 4YQ8A 1UAMA
chains in the Genus database with same CATH topology
1X7OA 1Z85A 3BBEA 4RG1A 4KDZA 4CNEA 1X7PA 4YQ3A 3KTYA 3L8UA 4YQBA 1VHYA 4YPYA 4YVIA 2V3JA 4YQLA 1GZ0A 4YQPA 4JWFA 4XBOA 3AXZA 3OINA 4YQIA 2I6DA 1P9PA 2EGWA 4JALA 3N4KA 3NK7A 2QMMA 1IPAA 5CO4A 4FAKA 4YQ5A 1UAJA 2V3KA 4YPXA 4KGNA 5D9FA 4H3ZA 4YQSA 3IC6A 4YPWA 4H3YA 4YQ1A 4YQRA 3ONPA 3BBDA 5GMCA 1J85A 4E8BA 4X3LA 2YY8A 2EGVA 1VHKA 3KW2A 4JWJA 1UAKA 4YQTA 4YQGA 3N4JA 2QWVA 1NXZA 4CNGA 4YQ7A 3ILKA 4JAKA 3E5YA 4CNFA 4YVGA 1UALA 4YQ0A 1MXIA 3GYQA 4YQ2A 4CNDA 3KNUA 4YQDA 4YQAA 1K3RA 4JWHA 4PZKA 3DCMX 5GM8A 2HA8A 4YQ6A 4L69A 4YPZA 1TO0A 4IG6A 1VH0A 4YQKA 4FMWA 4YVKA 4YQ4A 3NK6A 3OIJA 4YQ9A 2Z0YA 4X3MA 5FAIA 1V2XA 4YQOA 4JWGA 2O3AA 3AI9X 5GMBA 1ZJRA 4YVHA 1V6ZA 2NWAA 3IEFA 4YQCA 1O6DA 3QUVA 4YQQA 4YQNA 3BBHA 4MCCA 4YVJA 1OY5A 4MCDA 3OIIA 4YQJA 3AIAA 3KY7A 3O7BA 2CX8A 1NS5A 4J3CA 4MCBA 4YQ8A 1UAMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X7O A;  1Z85 A;  3BBE A;  4RG1 A;  4KDZ A;  4CNE A;  1X7P A;  4YQ3 A;  3KTY A;  3L8U A;  4YQB A;  1VHY A;  4YPY A;  4YVI A;  2V3J A;  4YQL A;  1GZ0 A;  4YQP A;  4XBO A;  3AXZ A;  3OIN A;  4YQI A;  2I6D A;  1P9P A;  2EGW A;  4JAL A;  3N4K A;  3NK7 A;  2QMM A;  1IPA A;  5CO4 A;  4FAK A;  4YQ5 A;  1UAJ A;  2V3K A;  4YPX A;  4KGN A;  5D9F A;  4H3Z A;  4YQS A;  3IC6 A;  4YPW A;  4H3Y A;  4YQ1 A;  4YQR A;  3ONP A;  3BBD A;  5GMC A;  1J85 A;  4E8B A;  4X3L A;  2YY8 A;  2EGV A;  1VHK A;  3KW2 A;  1UAK A;  4YQT A;  4YQG A;  3N4J A;  2QWV A;  1NXZ A;  4CNG A;  4YQ7 A;  3ILK A;  4JAK A;  3E5Y A;  4CNF A;  4YVG A;  1UAL A;  4YQ0 A;  1MXI A;  3GYQ A;  4YQ2 A;  4CND A;  3KNU A;  4YQD A;  4YQA A;  1K3R A;  4PZK A;  5GM8 A;  3DCM X;  2HA8 A;  4YQ6 A;  4L69 A;  4YPZ A;  1TO0 A;  4IG6 A;  1VH0 A;  4YQK A;  4YVK A;  3OIJ A;  4YQ4 A;  3NK6 A;  4YQ9 A;  2Z0Y A;  4X3M A;  5FAI A;  1V2X A;  4YQO A;  2O3A A;  3AI9 X;  5GMB A;  1ZJR A;  4YVH A;  1V6Z A;  2NWA A;  3IEF A;  4YQC A;  1O6D A;  3QUV A;  4YQQ A;  4YQN A;  3BBH A;  4MCC A;  4YVJ A;  1OY5 A;  4MCD A;  3OII A;  4YQJ A;  3AIA A;  3KY7 A;  3O7B A;  2CX8 A;  1NS5 A;  4J3C A;  4MCB A;  4YQ8 A;  1UAM A; 
#chains in the Genus database with same CATH topology
 1X7O A;  3X1L B;  4IOA S;  4IOC S;  1UDX A;  1Z85 A;  3BBE A;  4RG1 A;  3CZB A;  4KDZ A;  4CNE A;  1X7P A;  1QTQ A;  5JVH S;  2HZ7 A;  5DM7 S;  4YQ3 A;  4WFN S;  5JVG S;  3KTY A;  2ZJQ S;  1O0B A;  3L8U A;  4YQB A;  1VHY A;  4YPY A;  4YVI A;  5IZN A;  1FEU A;  3PIO S;  2V3J A;  4YQL A;  4IO9 S;  2RD2 A;  4WCE S;  1GZ0 A;  4YQP A;  4H4K A;  4JWF A;  4XBO A;  3AXZ A;  3OIN A;  4YQI A;  2I6D A;  1P9P A;  2EGW A;  4JAL A;  2QMM A;  1IPA A;  3N4K A;  3NK7 A;  5CO4 A;  4FAK A;  4YQ5 A;  1UAJ A;  2V3K A;  4YPX A;  4KGN A;  5D9F A;  3W2W B;  4H3Z A;  4YQS A;  2AE0 X;  3PIP S;  4JXX A;  4H3S A;  5GAE W;  3IC6 A;  3W2V B;  4YPW A;  5HL7 S;  2PNW A;  3AII A;  1EUY A;  4H3Y A;  2PJJ A;  5GAG W;  4YQ1 A;  2ZJR S;  1D6K A;  4YQR A;  3ONP A;  3BBD A;  5GMC A;  1EUQ A;  1J85 A;  2RE8 A;  4E8B A;  4X3L A;  2YY8 A;  2EGV A;  1NYL A;  1VHK A;  3KW2 A;  2GAE A;  2ZJP S;  4JWJ A;  4WFA S;  1UAK A;  4YQT A;  4YQG A;  3N4J A;  5GAD W;  2PI8 A;  2QWV A;  1QRT A;  4WF9 S;  1NXZ A;  5GAH W;  4CNG A;  4YQ7 A;  3ILK A;  4JAK A;  3E5Y A;  4CNF A;  3J7Z V;  1UAL A;  4YVG A;  4YQ0 A;  1MXI A;  1DFU P;  3GYQ A;  1QRU A;  4YQ2 A;  4CND A;  3KNU A;  4YQD A;  4YQA A;  1K3R A;  1GTR A;  2PIC A;  4JWH A;  4PZK A;  3DCM X;  5GM8 A;  2HA8 A;  1EXD A;  4YQ6 A;  4WFB S;  4L69 A;  4YPZ A;  4V19 4;  1TO0 A;  4IG6 A;  1VH0 A;  4P2B A;  4YQK A;  4FMW A;  3DLL S;  4YQ4 A;  3NK6 A;  4YVK A;  4YQ9 A;  3OIJ A;  2Z0Y A;  4X3M A;  5FAI A;  1V2X A;  4YQO A;  4JXZ A;  2G5D A;  4JWG A;  2O3A A;  1B75 A;  3AI9 X;  5GMB A;  5BNZ A;  1ZJR A;  5DM6 S;  4UY8 8;  1QRS A;  1ZJW A;  4YVH A;  1V6Z A;  2NWA A;  3IEF A;  4YQC A;  1O6D A;  3QUV A;  1GTS A;  4JYZ A;  4YQQ A;  4U67 S;  2G6G A;  3CF5 S;  4YQN A;  3BBH A;  4MCC A;  4YVJ A;  1OY5 A;  4MCD A;  3OII A;  4YQJ A;  1O0C A;  3AIA A;  3KY7 A;  3O7B A;  2CX8 A;  1NS5 A;  4J3C A;  4MCB A;  4YQ8 A;  1UAM A; 
#chains in the Genus database with same CATH homology
 1X7O A;  1Z85 A;  3BBE A;  4RG1 A;  4KDZ A;  4CNE A;  1X7P A;  4YQ3 A;  3KTY A;  3L8U A;  4YQB A;  1VHY A;  4YPY A;  4YVI A;  2V3J A;  4YQL A;  1GZ0 A;  4YQP A;  4JWF A;  4XBO A;  3AXZ A;  3OIN A;  4YQI A;  2I6D A;  1P9P A;  2EGW A;  4JAL A;  3N4K A;  3NK7 A;  2QMM A;  1IPA A;  5CO4 A;  4FAK A;  4YQ5 A;  1UAJ A;  2V3K A;  4YPX A;  4KGN A;  5D9F A;  4H3Z A;  4YQS A;  3IC6 A;  4YPW A;  4H3Y A;  4YQ1 A;  4YQR A;  3ONP A;  3BBD A;  5GMC A;  1J85 A;  4E8B A;  4X3L A;  2YY8 A;  2EGV A;  1VHK A;  3KW2 A;  4JWJ A;  1UAK A;  4YQT A;  4YQG A;  3N4J A;  2QWV A;  1NXZ A;  4CNG A;  4YQ7 A;  3ILK A;  4JAK A;  3E5Y A;  4CNF A;  4YVG A;  1UAL A;  4YQ0 A;  1MXI A;  3GYQ A;  4YQ2 A;  4CND A;  3KNU A;  4YQD A;  4YQA A;  1K3R A;  4JWH A;  4PZK A;  3DCM X;  5GM8 A;  2HA8 A;  4YQ6 A;  4L69 A;  4YPZ A;  1TO0 A;  4IG6 A;  1VH0 A;  4YQK A;  4FMW A;  4YVK A;  4YQ4 A;  3NK6 A;  3OIJ A;  4YQ9 A;  2Z0Y A;  4X3M A;  5FAI A;  1V2X A;  4YQO A;  4JWG A;  2O3A A;  3AI9 X;  5GMB A;  1ZJR A;  4YVH A;  1V6Z A;  2NWA A;  3IEF A;  4YQC A;  1O6D A;  3QUV A;  4YQQ A;  4YQN A;  3BBH A;  4MCC A;  4YVJ A;  1OY5 A;  4MCD A;  3OII A;  4YQJ A;  3AIA A;  3KY7 A;  3O7B A;  2CX8 A;  1NS5 A;  4J3C A;  4MCB A;  4YQ8 A;  1UAM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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