4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Transferase
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
4YQOA 1K3RA 2EGVA 4YPYA 3KTYA 3N4JA 4YQGA 3QUVA 3ONPA 4JAKA 1O6DA 1NS5A 1VHYA 4YQ4A 3OINA 3L8UA 2I6DA 4L69A 2V3KA 4RG1A 4X3LA 2Z0YA 1VHKA 4YQ8A 4YQNA 3IEFA 2CX8A 3NK7A 3N4KA 4YQ9A 1TO0A 5GM8A 4YQ5A 3O7BA 2V3JA 1NXZA 4YQ2A 4FAKA 4E8BA 1X7PA 4CNDA 4YQAA 1J85A 4YVIA 4YPWA 1UALA 4YVHA 4YQBA 4YQQA 1V6ZA 4YQ6A 3BBHA 4YQJA 4YQPA 3DCMX 3KW2A 3AXZA 4PZKA 4YQ1A 4YQRA 4CNGA 4KDZA 4YVJA 4YVKA 5D9FA 3BBEA 5GMBA 4YQSA 2YY8A 4H3ZA 1OY5A 1UAMA 4YQTA 5FAIA 3OIJA 1UAKA 3KNUA 4CNEA 2HA8A 3NK6A 4YVGA 4YQIA 4YQCA 1X7OA 4MCDA 3ILKA 4YQLA 3OIIA 2EGWA 3GYQA 5CO4A 1GZ0A 4YQ7A 1UAJA 1P9PA 2NWAA 1V2XA 4YQKA 4MCBA 1MXIA 4YQ3A 4YQ0A 3BBDA 1Z85A 2O3AA 3AI9X 4IG6A 4JALA 4H3YA 4KGNA 4X3MA 4CNFA 3IC6A 3KY7A 4J3CA 1ZJRA 3E5YA 1IPAA 2QWVA 4YQDA 4MCCA 4XBOA 4YPXA 5GMCA 1VH0A 2QMMA 3AIAA 4YPZA
chains in the Genus database with same CATH superfamily
4YQOA 1K3RA 1QTQA 2EGVA 4JYZA 1EUQA 4YPYA 3KTYA 1GTRA 3N4JA 3QUVA 1EUYA 3ONPA 4YQGA 4JAKA 1O6DA 4WF9S 1NS5A 2GAEA 1VHYA 4YQ4A 3OINA 5GAGW 3L8UA 5JVHS 2I6DA 5GAHW 4H4KA 5GAEW 4L69A 2V3KA 4RG1A 4JXZA 1B75A 4X3LA 2Z0YA 1VHKA 4YQ8A 4YQNA 3IEFA 2CX8A 4IOAS 3N4KA 3NK7A 4YQ9A 2AE0X 2HZ7A 1TO0A 5GM8A 3J7ZV 4YQ5A 1EXDA 1FEUA 3O7BA 2V3JA 1NXZA 1O0BA 4YQ2A 4FAKA 4V194 4U67S 5BNZA 2ZJQS 2RE8A 4E8BA 1X7PA 3W2WB 4CNDA 2PI8A 4UY88 4YQAA 2ZJPS 1J85A 4YVIA 4YPWA 3DLLS 1UALA 5DM6S 4YVHA 4YQBA 4WFAS 4YQQA 1V6ZA 4YQ6A 2PICA 1DFUP 5HL7S 3BBHA 4YQJA 4P2BA 4YQPA 3DCMX 3KW2A 3AXZA 4PZKA 4YQ1A 4YQRA 3AIIA 4CNGA 2ZJRS 4WFBS 4KDZA 5JVGS 1UDXA 4YVJA 4YVKA 5D9FA 5IZNA 3BBEA 2RD2A 5GMBA 4YQSA 2YY8A 4H3ZA 1OY5A 1UAMA 4YQTA 5FAIA 4JWHA 1NYLA 3OIJA 1UAKA 3KNUA 4CNEA 1ZJWA 1QRSA 2HA8A 3NK6A 4YVGA 4YQIA 3PIPS 4YQCA 4IO9S 1X7OA 4JWFA 4MCDA 3ILKA 4YQLA 1D6KA 3OIIA 2EGWA 3GYQA 5CO4A 1GZ0A 4YQ7A 1UAJA 3CF5S 1P9PA 2NWAA 3X1LB 1V2XA 4H3SA 4JWGA 1QRUA 4YQKA 1QRTA 4MCBA 1MXIA 4YQ3A 2G5DA 5DM7S 3CZBA 4WFNS 4JWJA 4JXXA 4YQ0A 3BBDA 1Z85A 2O3AA 3AI9X 4IG6A 4JALA 4H3YA 4KGNA 4X3MA 4CNFA 3IC6A 2G6GA 2PJJA 3KY7A 4J3CA 3PIOS 1ZJRA 3E5YA 1IPAA 2QWVA 4WCES 4YQDA 4FMWA 4MCCA 4XBOA 4IOCS 4YPXA 2PNWA 1O0CA 5GMCA 1VH0A 2QMMA 1GTSA 3W2VB 3AIAA 5GADW 4YPZA
chains in the Genus database with same CATH topology
4YQOA 1K3RA 2EGVA 4YPYA 3KTYA 3N4JA 4YQGA 3QUVA 3ONPA 4JAKA 1O6DA 1NS5A 1VHYA 4YQ4A 3OINA 3L8UA 2I6DA 4L69A 2V3KA 4RG1A 4X3LA 2Z0YA 1VHKA 4YQ8A 4YQNA 3IEFA 2CX8A 3NK7A 3N4KA 4YQ9A 1TO0A 5GM8A 4YQ5A 3O7BA 2V3JA 1NXZA 4YQ2A 4FAKA 4E8BA 1X7PA 4CNDA 4YQAA 1J85A 4YVIA 4YPWA 1UALA 4YVHA 4YQBA 4YQQA 1V6ZA 4YQ6A 3BBHA 4YQJA 4YQPA 3DCMX 3KW2A 3AXZA 4PZKA 4YQ1A 4YQRA 4CNGA 4KDZA 4YVJA 4YVKA 5D9FA 3BBEA 5GMBA 4YQSA 2YY8A 4H3ZA 1OY5A 1UAMA 4YQTA 5FAIA 4JWHA 3OIJA 1UAKA 3KNUA 4CNEA 2HA8A 3NK6A 4YVGA 4YQIA 4YQCA 1X7OA 4JWFA 4MCDA 3ILKA 4YQLA 3OIIA 2EGWA 3GYQA 5CO4A 1GZ0A 4YQ7A 1UAJA 1P9PA 2NWAA 1V2XA 4JWGA 4YQKA 4MCBA 1MXIA 4YQ3A 4JWJA 4YQ0A 3BBDA 1Z85A 2O3AA 3AI9X 4IG6A 4JALA 4H3YA 4KGNA 4X3MA 4CNFA 3IC6A 3KY7A 4J3CA 1ZJRA 3E5YA 1IPAA 2QWVA 4YQDA 4FMWA 4MCCA 4XBOA 4YPXA 5GMCA 1VH0A 2QMMA 3AIAA 4YPZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQO A;  1K3R A;  2EGV A;  4YPY A;  3KTY A;  3N4J A;  4YQG A;  3QUV A;  3ONP A;  4JAK A;  1O6D A;  1NS5 A;  1VHY A;  4YQ4 A;  3OIN A;  3L8U A;  2I6D A;  4L69 A;  2V3K A;  4RG1 A;  4X3L A;  2Z0Y A;  1VHK A;  4YQ8 A;  4YQN A;  3IEF A;  2CX8 A;  3NK7 A;  3N4K A;  4YQ9 A;  1TO0 A;  5GM8 A;  4YQ5 A;  3O7B A;  2V3J A;  1NXZ A;  4YQ2 A;  4FAK A;  4E8B A;  1X7P A;  4CND A;  4YQA A;  1J85 A;  4YVI A;  4YPW A;  1UAL A;  4YVH A;  4YQB A;  4YQQ A;  1V6Z A;  4YQ6 A;  3BBH A;  4YQJ A;  4YQP A;  3DCM X;  3KW2 A;  3AXZ A;  4PZK A;  4YQ1 A;  4YQR A;  4CNG A;  4KDZ A;  4YVJ A;  4YVK A;  5D9F A;  3BBE A;  5GMB A;  4YQS A;  2YY8 A;  4H3Z A;  1OY5 A;  1UAM A;  4YQT A;  5FAI A;  3OIJ A;  1UAK A;  3KNU A;  4CNE A;  2HA8 A;  3NK6 A;  4YVG A;  4YQI A;  4YQC A;  1X7O A;  4MCD A;  3ILK A;  4YQL A;  3OII A;  2EGW A;  3GYQ A;  5CO4 A;  1GZ0 A;  4YQ7 A;  1UAJ A;  1P9P A;  2NWA A;  1V2X A;  4YQK A;  4MCB A;  1MXI A;  4YQ3 A;  4YQ0 A;  3BBD A;  1Z85 A;  2O3A A;  3AI9 X;  4IG6 A;  4JAL A;  4H3Y A;  4KGN A;  4X3M A;  4CNF A;  3IC6 A;  3KY7 A;  4J3C A;  1ZJR A;  3E5Y A;  1IPA A;  2QWV A;  4YQD A;  4MCC A;  4XBO A;  4YPX A;  5GMC A;  1VH0 A;  2QMM A;  3AIA A;  4YPZ A; 
#chains in the Genus database with same CATH topology
 4YQO A;  1K3R A;  1QTQ A;  2EGV A;  4JYZ A;  1EUQ A;  4YPY A;  3KTY A;  1GTR A;  3N4J A;  3QUV A;  1EUY A;  3ONP A;  4YQG A;  4JAK A;  1O6D A;  4WF9 S;  1NS5 A;  2GAE A;  1VHY A;  4YQ4 A;  3OIN A;  5GAG W;  3L8U A;  5JVH S;  2I6D A;  5GAH W;  4H4K A;  5GAE W;  4L69 A;  2V3K A;  4RG1 A;  4JXZ A;  1B75 A;  4X3L A;  2Z0Y A;  1VHK A;  4YQ8 A;  4YQN A;  3IEF A;  2CX8 A;  4IOA S;  3N4K A;  3NK7 A;  4YQ9 A;  2AE0 X;  2HZ7 A;  1TO0 A;  5GM8 A;  3J7Z V;  4YQ5 A;  1EXD A;  1FEU A;  3O7B A;  2V3J A;  1NXZ A;  1O0B A;  4YQ2 A;  4FAK A;  4V19 4;  4U67 S;  5BNZ A;  2ZJQ S;  2RE8 A;  4E8B A;  1X7P A;  3W2W B;  4CND A;  2PI8 A;  4UY8 8;  4YQA A;  2ZJP S;  1J85 A;  4YVI A;  4YPW A;  3DLL S;  1UAL A;  5DM6 S;  4YVH A;  4YQB A;  4WFA S;  4YQQ A;  1V6Z A;  4YQ6 A;  2PIC A;  1DFU P;  5HL7 S;  3BBH A;  4YQJ A;  4P2B A;  4YQP A;  3DCM X;  3KW2 A;  3AXZ A;  4PZK A;  4YQ1 A;  4YQR A;  3AII A;  4CNG A;  2ZJR S;  4WFB S;  4KDZ A;  5JVG S;  1UDX A;  4YVJ A;  4YVK A;  5D9F A;  5IZN A;  3BBE A;  2RD2 A;  5GMB A;  4YQS A;  2YY8 A;  4H3Z A;  1OY5 A;  1UAM A;  4YQT A;  5FAI A;  4JWH A;  1NYL A;  3OIJ A;  1UAK A;  3KNU A;  4CNE A;  1ZJW A;  1QRS A;  2HA8 A;  3NK6 A;  4YVG A;  4YQI A;  3PIP S;  4YQC A;  4IO9 S;  1X7O A;  4JWF A;  4MCD A;  3ILK A;  4YQL A;  1D6K A;  3OII A;  2EGW A;  3GYQ A;  5CO4 A;  1GZ0 A;  4YQ7 A;  1UAJ A;  3CF5 S;  1P9P A;  2NWA A;  3X1L B;  1V2X A;  4H3S A;  4JWG A;  1QRU A;  4YQK A;  1QRT A;  4MCB A;  1MXI A;  4YQ3 A;  2G5D A;  5DM7 S;  3CZB A;  4WFN S;  4JWJ A;  4JXX A;  4YQ0 A;  3BBD A;  1Z85 A;  2O3A A;  3AI9 X;  4IG6 A;  4JAL A;  4H3Y A;  4KGN A;  4X3M A;  4CNF A;  3IC6 A;  2G6G A;  2PJJ A;  3KY7 A;  4J3C A;  3PIO S;  1ZJR A;  3E5Y A;  1IPA A;  2QWV A;  4WCE S;  4YQD A;  4FMW A;  4MCC A;  4XBO A;  4IOC S;  4YPX A;  2PNW A;  1O0C A;  5GMC A;  1VH0 A;  2QMM A;  1GTS A;  3W2V B;  3AIA A;  5GAD W;  4YPZ A; 
#chains in the Genus database with same CATH homology
 4YQO A;  1K3R A;  2EGV A;  4YPY A;  3KTY A;  3N4J A;  4YQG A;  3QUV A;  3ONP A;  4JAK A;  1O6D A;  1NS5 A;  1VHY A;  4YQ4 A;  3OIN A;  3L8U A;  2I6D A;  4L69 A;  2V3K A;  4RG1 A;  4X3L A;  2Z0Y A;  1VHK A;  4YQ8 A;  4YQN A;  3IEF A;  2CX8 A;  3NK7 A;  3N4K A;  4YQ9 A;  1TO0 A;  5GM8 A;  4YQ5 A;  3O7B A;  2V3J A;  1NXZ A;  4YQ2 A;  4FAK A;  4E8B A;  1X7P A;  4CND A;  4YQA A;  1J85 A;  4YVI A;  4YPW A;  1UAL A;  4YVH A;  4YQB A;  4YQQ A;  1V6Z A;  4YQ6 A;  3BBH A;  4YQJ A;  4YQP A;  3DCM X;  3KW2 A;  3AXZ A;  4PZK A;  4YQ1 A;  4YQR A;  4CNG A;  4KDZ A;  4YVJ A;  4YVK A;  5D9F A;  3BBE A;  5GMB A;  4YQS A;  2YY8 A;  4H3Z A;  1OY5 A;  1UAM A;  4YQT A;  5FAI A;  4JWH A;  3OIJ A;  1UAK A;  3KNU A;  4CNE A;  2HA8 A;  3NK6 A;  4YVG A;  4YQI A;  4YQC A;  1X7O A;  4JWF A;  4MCD A;  3ILK A;  4YQL A;  3OII A;  2EGW A;  3GYQ A;  5CO4 A;  1GZ0 A;  4YQ7 A;  1UAJ A;  1P9P A;  2NWA A;  1V2X A;  4JWG A;  4YQK A;  4MCB A;  1MXI A;  4YQ3 A;  4JWJ A;  4YQ0 A;  3BBD A;  1Z85 A;  2O3A A;  3AI9 X;  4IG6 A;  4JAL A;  4H3Y A;  4KGN A;  4X3M A;  4CNF A;  3IC6 A;  3KY7 A;  4J3C A;  1ZJR A;  3E5Y A;  1IPA A;  2QWV A;  4YQD A;  4FMW A;  4MCC A;  4XBO A;  4YPX A;  5GMC A;  1VH0 A;  2QMM A;  3AIA A;  4YPZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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