4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
b'VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Transferase
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
5GM8A 5GMCA 2QMMA 3KTYA 4YQ7A 4CNFA 3OINA 4YQOA 4YQQA 3KW2A 3ILKA 4MCDA 3E5YA 4E8BA 4MCBA 1V2XA 4CNGA 1P9PA 3AXZA 2QWVA 4MCCA 4YQIA 4YQ1A 4YQNA 4JALA 4YQ0A 5CO4A 5D9FA 3OIJA 4YQ8A 2NWAA 4RG1A 4J3CA 2EGWA 4CNDA 4CNEA 1NS5A 4YQTA 4IG6A 3N4JA 1UALA 5GMBA 1UAJA 4YQDA 3ONPA 3AIAA 2I6DA 1NXZA 1GZ0A 3N4KA 3O7BA 4YPYA 1K3RA 4H3ZA 1Z85A 4XBOA 4YQGA 4YVGA 1VHKA 4YPWA 4YQBA 1X7OA 1IPAA 4YQPA 4L69A 2V3KA 4YQSA 3BBDA 1X7PA 2EGVA 4YVIA 4YQ2A 4FAKA 4YQJA 1UAKA 1VH0A 1OY5A 1V6ZA 1TO0A 4YVJA 4YQ6A 2O3AA 2YY8A 4YVHA 3NK7A 4KDZA 1J85A 3DCMX 3QUVA 2CX8A 4KGNA 2Z0YA 4YQ4A 4YQ5A 1ZJRA 4YPXA 4YQ9A 2V3JA 4YQLA 4YQ3A 4YQRA 3KNUA 3KY7A 4YQCA 3BBHA 1O6DA 4PZKA 3NK6A 4YPZA 4YQAA 3OIIA 3IEFA 3IC6A 4X3LA 3BBEA 3GYQA 5FAIA 3L8UA 4X3MA 4H3YA 2HA8A 4YVKA 1VHYA 1MXIA 3AI9X 4JAKA 1UAMA 4YQKA
chains in the Genus database with same CATH superfamily
1B75A 5GM8A 5GMCA 5GADW 2QMMA 2PI8A 3KTYA 4YQ7A 4CNFA 3OINA 4YQOA 4FMWA 4YQQA 3KW2A 3ILKA 1EUQA 2PJJA 4MCDA 3E5YA 4E8BA 2G5DA 3DLLS 1EXDA 4MCBA 5JVGS 1V2XA 4CNGA 1P9PA 3AXZA 2QWVA 4MCCA 4YQIA 3X1LB 4YQ1A 4YQNA 1FEUA 4JALA 4YQ0A 5CO4A 5D9FA 4JXZA 3OIJA 4JWGA 4YQ8A 2NWAA 4RG1A 4J3CA 1GTRA 2RD2A 2EGWA 1DFUP 5GAGW 4CNDA 2HZ7A 4CNEA 1NS5A 4YQTA 5IZNA 1QTQA 4UY88 4IO9S 4IG6A 3N4JA 1UALA 5GMBA 1UAJA 4IOAS 4JWHA 4YQDA 4WFNS 2PICA 4H4KA 3ONPA 3AIAA 2I6DA 1NXZA 1GZ0A 3N4KA 3O7BA 3AIIA 2ZJPS 4YPYA 5DM6S 1K3RA 1ZJWA 4H3ZA 1EUYA 2G6GA 1Z85A 5BNZA 2ZJRS 4XBOA 4WF9S 4YQGA 5GAHW 3CF5S 5HL7S 1NYLA 1VHKA 4YVGA 4YPWA 4YQBA 1X7OA 1IPAA 4YQPA 4L69A 2V3KA 4YQSA 3PIPS 5DM7S 1GTSA 3BBDA 3W2VB 1O0BA 2EGVA 1X7PA 4YVIA 4V194 2PNWA 4YQ2A 4FAKA 4YQJA 1UAKA 1VH0A 5JVHS 4H3SA 3W2WB 1OY5A 1V6ZA 1TO0A 3PIOS 4YVJA 4YQ6A 2O3AA 4JWJA 2YY8A 4YVHA 3NK7A 4WFAS 4KDZA 2RE8A 4WFBS 4WCES 4P2BA 1J85A 3DCMX 3QUVA 2CX8A 5GAEW 4KGNA 2Z0YA 4YQ4A 4YQ5A 1ZJRA 4YPXA 3J7ZV 4YQ9A 2V3JA 3CZBA 2ZJQS 4YQLA 4YQ3A 4YQRA 3KNUA 4U67S 2GAEA 1QRTA 3KY7A 1UDXA 4YQCA 4JYZA 3BBHA 1O6DA 4PZKA 3NK6A 4YPZA 4YQAA 3OIIA 3IEFA 1QRUA 4JWFA 3IC6A 4X3LA 3BBEA 1O0CA 3GYQA 4IOCS 5FAIA 3L8UA 4X3MA 4H3YA 4JXXA 1D6KA 2HA8A 1QRSA 4YVKA 1VHYA 2AE0X 1MXIA 3AI9X 4JAKA 1UAMA 4YQKA
chains in the Genus database with same CATH topology
5GM8A 5GMCA 2QMMA 3KTYA 4YQ7A 4CNFA 3OINA 4YQOA 4FMWA 4YQQA 3KW2A 3ILKA 4MCDA 3E5YA 4E8BA 4MCBA 1V2XA 4CNGA 1P9PA 3AXZA 2QWVA 4MCCA 4YQIA 4YQ1A 4YQNA 4JALA 4YQ0A 5CO4A 5D9FA 3OIJA 4JWGA 4YQ8A 2NWAA 4RG1A 4J3CA 2EGWA 4CNDA 4CNEA 1NS5A 4YQTA 4IG6A 3N4JA 1UALA 5GMBA 1UAJA 4JWHA 4YQDA 3ONPA 3AIAA 2I6DA 1NXZA 1GZ0A 3N4KA 3O7BA 4YPYA 1K3RA 4H3ZA 1Z85A 4XBOA 4YQGA 4YVGA 1VHKA 4YPWA 4YQBA 1X7OA 1IPAA 4YQPA 4L69A 2V3KA 4YQSA 3BBDA 1X7PA 2EGVA 4YVIA 4YQ2A 4FAKA 4YQJA 1UAKA 1VH0A 1OY5A 1V6ZA 1TO0A 4YVJA 4YQ6A 2O3AA 4JWJA 2YY8A 4YVHA 3NK7A 4KDZA 1J85A 3DCMX 3QUVA 2CX8A 4KGNA 2Z0YA 4YQ4A 4YQ5A 1ZJRA 4YPXA 4YQ9A 2V3JA 4YQLA 4YQ3A 4YQRA 3KNUA 3KY7A 4YQCA 3BBHA 1O6DA 4PZKA 3NK6A 4YPZA 4YQAA 3OIIA 3IEFA 4JWFA 3IC6A 4X3LA 3BBEA 3GYQA 5FAIA 3L8UA 4X3MA 4H3YA 2HA8A 4YVKA 1VHYA 1MXIA 3AI9X 4JAKA 1UAMA 4YQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GM8 A;  5GMC A;  2QMM A;  3KTY A;  4YQ7 A;  4CNF A;  3OIN A;  4YQO A;  4YQQ A;  3KW2 A;  3ILK A;  4MCD A;  3E5Y A;  4E8B A;  4MCB A;  1V2X A;  4CNG A;  1P9P A;  3AXZ A;  2QWV A;  4MCC A;  4YQI A;  4YQ1 A;  4YQN A;  4JAL A;  4YQ0 A;  5CO4 A;  5D9F A;  3OIJ A;  4YQ8 A;  2NWA A;  4RG1 A;  4J3C A;  2EGW A;  4CND A;  4CNE A;  1NS5 A;  4YQT A;  4IG6 A;  3N4J A;  1UAL A;  5GMB A;  1UAJ A;  4YQD A;  3ONP A;  3AIA A;  2I6D A;  1NXZ A;  1GZ0 A;  3N4K A;  3O7B A;  4YPY A;  1K3R A;  4H3Z A;  1Z85 A;  4XBO A;  4YQG A;  4YVG A;  1VHK A;  4YPW A;  4YQB A;  1X7O A;  1IPA A;  4YQP A;  4L69 A;  2V3K A;  4YQS A;  3BBD A;  1X7P A;  2EGV A;  4YVI A;  4YQ2 A;  4FAK A;  4YQJ A;  1UAK A;  1VH0 A;  1OY5 A;  1V6Z A;  1TO0 A;  4YVJ A;  4YQ6 A;  2O3A A;  2YY8 A;  4YVH A;  3NK7 A;  4KDZ A;  1J85 A;  3DCM X;  3QUV A;  2CX8 A;  4KGN A;  2Z0Y A;  4YQ4 A;  4YQ5 A;  1ZJR A;  4YPX A;  4YQ9 A;  2V3J A;  4YQL A;  4YQ3 A;  4YQR A;  3KNU A;  3KY7 A;  4YQC A;  3BBH A;  1O6D A;  4PZK A;  3NK6 A;  4YPZ A;  4YQA A;  3OII A;  3IEF A;  3IC6 A;  4X3L A;  3BBE A;  3GYQ A;  5FAI A;  3L8U A;  4X3M A;  4H3Y A;  2HA8 A;  4YVK A;  1VHY A;  1MXI A;  3AI9 X;  4JAK A;  1UAM A;  4YQK A; 
#chains in the Genus database with same CATH topology
 1B75 A;  5GM8 A;  5GMC A;  5GAD W;  2QMM A;  2PI8 A;  3KTY A;  4YQ7 A;  4CNF A;  3OIN A;  4YQO A;  4FMW A;  4YQQ A;  3KW2 A;  3ILK A;  1EUQ A;  2PJJ A;  4MCD A;  3E5Y A;  4E8B A;  2G5D A;  3DLL S;  1EXD A;  4MCB A;  5JVG S;  1V2X A;  4CNG A;  1P9P A;  3AXZ A;  2QWV A;  4MCC A;  4YQI A;  3X1L B;  4YQ1 A;  4YQN A;  1FEU A;  4JAL A;  4YQ0 A;  5CO4 A;  5D9F A;  4JXZ A;  3OIJ A;  4JWG A;  4YQ8 A;  2NWA A;  4RG1 A;  4J3C A;  1GTR A;  2RD2 A;  2EGW A;  1DFU P;  5GAG W;  4CND A;  2HZ7 A;  4CNE A;  1NS5 A;  4YQT A;  5IZN A;  1QTQ A;  4UY8 8;  4IO9 S;  4IG6 A;  3N4J A;  1UAL A;  5GMB A;  1UAJ A;  4IOA S;  4JWH A;  4YQD A;  4WFN S;  2PIC A;  4H4K A;  3ONP A;  3AIA A;  2I6D A;  1NXZ A;  1GZ0 A;  3N4K A;  3O7B A;  3AII A;  2ZJP S;  4YPY A;  5DM6 S;  1K3R A;  1ZJW A;  4H3Z A;  1EUY A;  2G6G A;  1Z85 A;  5BNZ A;  2ZJR S;  4XBO A;  4WF9 S;  4YQG A;  5GAH W;  3CF5 S;  5HL7 S;  1NYL A;  1VHK A;  4YVG A;  4YPW A;  4YQB A;  1X7O A;  1IPA A;  4YQP A;  4L69 A;  2V3K A;  4YQS A;  3PIP S;  5DM7 S;  1GTS A;  3BBD A;  3W2V B;  1O0B A;  2EGV A;  1X7P A;  4YVI A;  4V19 4;  2PNW A;  4YQ2 A;  4FAK A;  4YQJ A;  1UAK A;  1VH0 A;  5JVH S;  4H3S A;  3W2W B;  1OY5 A;  1V6Z A;  1TO0 A;  3PIO S;  4YVJ A;  4YQ6 A;  2O3A A;  4JWJ A;  2YY8 A;  4YVH A;  3NK7 A;  4WFA S;  4KDZ A;  2RE8 A;  4WFB S;  4WCE S;  4P2B A;  1J85 A;  3DCM X;  3QUV A;  2CX8 A;  5GAE W;  4KGN A;  2Z0Y A;  4YQ4 A;  4YQ5 A;  1ZJR A;  4YPX A;  3J7Z V;  4YQ9 A;  2V3J A;  3CZB A;  2ZJQ S;  4YQL A;  4YQ3 A;  4YQR A;  3KNU A;  4U67 S;  2GAE A;  1QRT A;  3KY7 A;  1UDX A;  4YQC A;  4JYZ A;  3BBH A;  1O6D A;  4PZK A;  3NK6 A;  4YPZ A;  4YQA A;  3OII A;  3IEF A;  1QRU A;  4JWF A;  3IC6 A;  4X3L A;  3BBE A;  1O0C A;  3GYQ A;  4IOC S;  5FAI A;  3L8U A;  4X3M A;  4H3Y A;  4JXX A;  1D6K A;  2HA8 A;  1QRS A;  4YVK A;  1VHY A;  2AE0 X;  1MXI A;  3AI9 X;  4JAK A;  1UAM A;  4YQK A; 
#chains in the Genus database with same CATH homology
 5GM8 A;  5GMC A;  2QMM A;  3KTY A;  4YQ7 A;  4CNF A;  3OIN A;  4YQO A;  4FMW A;  4YQQ A;  3KW2 A;  3ILK A;  4MCD A;  3E5Y A;  4E8B A;  4MCB A;  1V2X A;  4CNG A;  1P9P A;  3AXZ A;  2QWV A;  4MCC A;  4YQI A;  4YQ1 A;  4YQN A;  4JAL A;  4YQ0 A;  5CO4 A;  5D9F A;  3OIJ A;  4JWG A;  4YQ8 A;  2NWA A;  4RG1 A;  4J3C A;  2EGW A;  4CND A;  4CNE A;  1NS5 A;  4YQT A;  4IG6 A;  3N4J A;  1UAL A;  5GMB A;  1UAJ A;  4JWH A;  4YQD A;  3ONP A;  3AIA A;  2I6D A;  1NXZ A;  1GZ0 A;  3N4K A;  3O7B A;  4YPY A;  1K3R A;  4H3Z A;  1Z85 A;  4XBO A;  4YQG A;  4YVG A;  1VHK A;  4YPW A;  4YQB A;  1X7O A;  1IPA A;  4YQP A;  4L69 A;  2V3K A;  4YQS A;  3BBD A;  1X7P A;  2EGV A;  4YVI A;  4YQ2 A;  4FAK A;  4YQJ A;  1UAK A;  1VH0 A;  1OY5 A;  1V6Z A;  1TO0 A;  4YVJ A;  4YQ6 A;  2O3A A;  4JWJ A;  2YY8 A;  4YVH A;  3NK7 A;  4KDZ A;  1J85 A;  3DCM X;  3QUV A;  2CX8 A;  4KGN A;  2Z0Y A;  4YQ4 A;  4YQ5 A;  1ZJR A;  4YPX A;  4YQ9 A;  2V3J A;  4YQL A;  4YQ3 A;  4YQR A;  3KNU A;  3KY7 A;  4YQC A;  3BBH A;  1O6D A;  4PZK A;  3NK6 A;  4YPZ A;  4YQA A;  3OII A;  3IEF A;  4JWF A;  3IC6 A;  4X3L A;  3BBE A;  3GYQ A;  5FAI A;  3L8U A;  4X3M A;  4H3Y A;  2HA8 A;  4YVK A;  1VHY A;  1MXI A;  3AI9 X;  4JAK A;  1UAM A;  4YQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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