4LA0A

X-ray study of human serum albumin complexed with bicalutamide
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
581
structure length
581
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural studies of several clinically important oncology drugs in complex with human serum albumin.
pubmed doi rcsb
molecule tags Transport protein
total genus 226
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A05
5IIUA 1HK3A 3B9MA 4N0UD 1N5UA 1BM0A 2BXAA 2XW1A 4ZBRA 4Z69A 4LA0A 4N0FD 5IIHA 1O9XA 4HGMB 1E7CA 1BKEA 5IJFA 4EMXA 1MA9A 5GHKA 1E7IA 4L9KA 2BXQA 2BXHA 4ZBQA 2XVQA 2BXIA 3B9LA 4F5SA 1E7BA 5IFOA 1HK5A 1E7HA 3V09A 1KXPD 1TF0A 4L8UA 1HK2A 2XSIA 3LU6A 2BXNA 2BXMA 2BXFA 4OR0A 2BXPA 2BXOA 2BXEA 2BXCA 2I2ZA 2XVUA 4F5VA 4L9QA 4F5UA 4K71A 4LUHA 2VDBA 2VUEA 5DBYA 2BXGA 3SQJA 1LOTA 3CX9A 2BX8A 1E78A 1AO6A 4E99A 1J78A 5IJEA 3JQZA 4J2VA 2XVWA 5ID7A 3TDLA 5IJ5A 4PO0A 4F5TA 1GNIA 2I30A 2XVVA 3UIVA 3A73A 1J7EA 4IW1A 4S1YA 2BXDA 1HK4A 1GNJA 2VUFA 5HOZA 5IIXA 2BXKA 3JRYA 1BJ5A 1E7EA 1E7FA 4K2CA 4HGKA 1HK1A 4LB9A 3V03A 5FUOA 2YDFA 4G03A 3V08A 4JK4A 4OT2A 3LU8A 3LU7A 1UORA 4G04A 4LUFA 5DQFA 1E7AA 5ID9A 1E7GA 1KW2A 2BXLA 2BXBA 2XW0A 4IW2A 1H9ZA 1HA2A 4LB2A 4BKEA
chains in the Genus database with same CATH superfamily
5IIUA 4OTUA 2GUTA 5GINA 1HK3A 3B9MA 4D7XA 4ZUXV 2AJEA 2DG5A 4N0UD 1N5UA 3ECPA 1BM0A 2BXAA 2XW1A 4ZBRA 1SB0A 2K0NA 1VFIA 3G9KD 3NVMA 4LA0A 4N0FD 4Z69A 5IIHA 1O9XA 2Z8KA 3SIVB 1LNSA 4HGMB 1E7CA 3SIUB 1BKEA 4ZCGA 3M99C 3GQXA 5IJFA 4EMXA 1MA9A 3MHHB 3MHSB 5GHKA 1E7IA 4L9KA 2BXQA 2BXHA 2EFHA 2XVQA 2BXIA 4ZBQA 3B9LA 4DHXB 4F5SA 2DBXA 1E7BA 5IFOA 1HK5A 3BPJA 4NAWB 1E7HA 2V36A 2LXTA 4BY9C 4GG2A 3V09A 1KXPD 1TF0A 3H37A 5GIOA 4L8UA 2Z8JA 1NT2B 3PLAA 2XMOA 2EFCA 1HK2A 3WHSA 2XSIA 3LU6A 2DYMA 5GIPA 2BXNA 1MUSA 2NQOA 2BXMA 2BXFA 4C31B 2LQIA 4OR0A 1IJGA 2BXPA 4TQ1A 2EFEA 3H3AA 2BXOA 4FJCB 2BXEA 2BXCA 2CKXA 2I2ZA 4TQ0A 4W4UB 2LXSA 2XVUA 3VQIA 3ICXA 2KBZA 4F5VA 3NVIA 4L9QA 4F5UA 3FWCC 4K71A 3WHRA 4LUHA 2VDBA 2VUEA 5DBYA 2BXGA 2QM6A 2E0YA 1LOTA 3SQJA 3CX9A 4ZC6A 3A75A 2BX8A 1E78A 4Z9OA 2KWFA 4WA6B 1AO6A 2DBWA 4GDXA 4FK5B 5BPKA 1MIVA 4E99A 1J78A 2JUHA 5IJEA 2OZBB 2DYOA 3JQZA 4J2VA 2XVWA 5ID7A 5D7GA 5IJ5A 3TDLA 4PO0A 4F5TA 4I9OA 1GNIA 5B5TA 2I30A 4GDLB 4GDKB 2XVVA 3UIVA 3A73A 1MUHA 1MIYA 1TXUA 2Z8IA 3W1SA 3FNMA 3WHQA 3NVKA 1J7EA 4IW1A 4S1YA 2BXDA 1HK4A 1GNJA 2AGHB 2VUFA 2NNWA 5HOZA 5IIXA 1KDXA 2BXKA 3JRYA 2ROHA 2EFDA 1BJ5A 1E7EA 1E7FA 4K2CA 2OT3A 4ZBKA 4HGKA 1FOUA 3FWBC 2LOQA 1HK1A 2QHBA 4LB9A 3V03A 3NMUA 5FUOA 1JNBA 2YDFA 4G03A 3V08A 4DM0A 2DBUA 4JK4A 2QMCA 4OT2A 3LU8A 3GQUA 2LQHA 4N3ZA 3LU7A 1UORA 4G04A 1MM8A 1MIWA 4G01A 3KJLA 1H5WA 4MBEC 4LUFA 2E0XA 5DQFA 1E7AA 5ID9A 1E7GA 3KIKA 1KW2A 2BXLA 2BXBA 4OTTA 2XW0A 4IW2A 1H9ZA 1HA2A 4FIPB 4M70B 4LB2A 1VZSA 3GA9L 4BKEA
chains in the Genus database with same CATH topology
5IIUA 4OTUA 5GINA 1HK3A 3B9MA 4ZUXV 2AJEA 2DG5A 4N0UD 1N5UA 1BM0A 2BXAA 2XW1A 4ZBRA 4Z69A 1VFIA 3G9KD 3NVMA 4LA0A 4N0FD 5IIHA 1O9XA 2Z8KA 3SIVB 1LNSA 4HGMB 1E7CA 3SIUB 1BKEA 4ZCGA 3M99C 3GQXA 5IJFA 4EMXA 1MA9A 3MHHB 3MHSB 5GHKA 1E7IA 4L9KA 2BXQA 2BXHA 2EFHA 2XVQA 2BXIA 4ZBQA 3B9LA 4DHXB 4F5SA 2DBXA 1E7BA 5IFOA 1HK5A 4NAWB 4BY9C 1E7HA 2V36A 4GG2A 3V09A 1KXPD 1TF0A 3H37A 5GIOA 4L8UA 2Z8JA 1NT2B 3PLAA 2XMOA 2EFCA 1HK2A 3WHSA 2XSIA 3LU6A 2DYMA 5GIPA 2BXNA 2NQOA 2BXMA 2BXFA 4C31B 4OR0A 1IJGA 2BXPA 4TQ1A 2EFEA 3H3AA 2BXOA 4FJCB 2BXEA 2BXCA 2CKXA 2I2ZA 4TQ0A 4W4UB 2XVUA 3VQIA 3ICXA 2KBZA 4F5VA 3NVIA 4L9QA 4F5UA 3FWCC 4K71A 3WHRA 4LUHA 2VDBA 2VUEA 5DBYA 2BXGA 2QM6A 2E0YA 1LOTA 3SQJA 3CX9A 4ZC6A 3A75A 2BX8A 1E78A 4Z9OA 4WA6B 1AO6A 2DBWA 4GDXA 4FK5B 5BPKA 1MIVA 4E99A 1J78A 2JUHA 5IJEA 2OZBB 2DYOA 3JQZA 4J2VA 2XVWA 5ID7A 5D7GA 5IJ5A 3TDLA 4PO0A 4F5TA 1GNIA 5B5TA 2I30A 4GDLB 4GDKB 2XVVA 3UIVA 3A73A 1MIYA 1TXUA 2Z8IA 3W1SA 3FNMA 3WHQA 3NVKA 1J7EA 4IW1A 4S1YA 2BXDA 1HK4A 1GNJA 2VUFA 2NNWA 5HOZA 5IIXA 2BXKA 3JRYA 2ROHA 2EFDA 1BJ5A 1E7EA 1E7FA 4K2CA 2OT3A 4ZBKA 4HGKA 1FOUA 3FWBC 2LOQA 1HK1A 2QHBA 4LB9A 3V03A 3NMUA 5FUOA 1JNBA 2YDFA 4G03A 3V08A 2DBUA 4JK4A 2QMCA 4OT2A 3LU8A 3GQUA 4N3ZA 3LU7A 1UORA 4G04A 1MIWA 4G01A 3KJLA 1H5WA 4MBEC 4LUFA 2E0XA 5DQFA 1E7AA 5ID9A 1E7GA 3KIKA 1KW2A 2BXLA 2BXBA 4OTTA 2XW0A 4IW2A 1H9ZA 1HA2A 4FIPB 4M70B 4LB2A 1VZSA 3GA9L 4BKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IIU A;  1HK3 A;  3B9M A;  4N0U D;  1N5U A;  1BM0 A;  2BXA A;  2XW1 A;  4ZBR A;  4Z69 A;  4LA0 A;  4N0F D;  5IIH A;  1O9X A;  4HGM B;  1E7C A;  1BKE A;  5IJF A;  4EMX A;  1MA9 A;  5GHK A;  1E7I A;  4L9K A;  2BXQ A;  2BXH A;  4ZBQ A;  2XVQ A;  2BXI A;  3B9L A;  4F5S A;  1E7B A;  5IFO A;  1HK5 A;  1E7H A;  3V09 A;  1KXP D;  1TF0 A;  4L8U A;  1HK2 A;  2XSI A;  3LU6 A;  2BXN A;  2BXM A;  2BXF A;  4OR0 A;  2BXP A;  2BXO A;  2BXE A;  2BXC A;  2I2Z A;  2XVU A;  4F5V A;  4L9Q A;  4F5U A;  4K71 A;  4LUH A;  2VDB A;  2VUE A;  5DBY A;  2BXG A;  3SQJ A;  1LOT A;  3CX9 A;  2BX8 A;  1E78 A;  1AO6 A;  4E99 A;  1J78 A;  5IJE A;  3JQZ A;  4J2V A;  2XVW A;  5ID7 A;  3TDL A;  5IJ5 A;  4PO0 A;  4F5T A;  1GNI A;  2I30 A;  2XVV A;  3UIV A;  3A73 A;  1J7E A;  4IW1 A;  4S1Y A;  2BXD A;  1HK4 A;  1GNJ A;  2VUF A;  5HOZ A;  5IIX A;  2BXK A;  3JRY A;  1BJ5 A;  1E7E A;  1E7F A;  4K2C A;  4HGK A;  1HK1 A;  4LB9 A;  3V03 A;  5FUO A;  2YDF A;  4G03 A;  3V08 A;  4JK4 A;  4OT2 A;  3LU8 A;  3LU7 A;  1UOR A;  4G04 A;  4LUF A;  5DQF A;  1E7A A;  5ID9 A;  1E7G A;  1KW2 A;  2BXL A;  2BXB A;  2XW0 A;  4IW2 A;  1H9Z A;  1HA2 A;  4LB2 A;  4BKE A; 
#chains in the Genus database with same CATH topology
 5IIU A;  4OTU A;  2GUT A;  5GIN A;  1HK3 A;  3B9M A;  4D7X A;  4ZUX V;  2AJE A;  2DG5 A;  4N0U D;  1N5U A;  3ECP A;  1BM0 A;  2BXA A;  2XW1 A;  4ZBR A;  1SB0 A;  2K0N A;  1VFI A;  3G9K D;  3NVM A;  4LA0 A;  4N0F D;  4Z69 A;  5IIH A;  1O9X A;  2Z8K A;  3SIV B;  1LNS A;  4HGM B;  1E7C A;  3SIU B;  1BKE A;  4ZCG A;  3M99 C;  3GQX A;  5IJF A;  4EMX A;  1MA9 A;  3MHH B;  3MHS B;  5GHK A;  1E7I A;  4L9K A;  2BXQ A;  2BXH A;  2EFH A;  2XVQ A;  2BXI A;  4ZBQ A;  3B9L A;  4DHX B;  4F5S A;  2DBX A;  1E7B A;  5IFO A;  1HK5 A;  3BPJ A;  4NAW B;  1E7H A;  2V36 A;  2LXT A;  4BY9 C;  4GG2 A;  3V09 A;  1KXP D;  1TF0 A;  3H37 A;  5GIO A;  4L8U A;  2Z8J A;  1NT2 B;  3PLA A;  2XMO A;  2EFC A;  1HK2 A;  3WHS A;  2XSI A;  3LU6 A;  2DYM A;  5GIP A;  2BXN A;  1MUS A;  2NQO A;  2BXM A;  2BXF A;  4C31 B;  2LQI A;  4OR0 A;  1IJG A;  2BXP A;  4TQ1 A;  2EFE A;  3H3A A;  2BXO A;  4FJC B;  2BXE A;  2BXC A;  2CKX A;  2I2Z A;  4TQ0 A;  4W4U B;  2LXS A;  2XVU A;  3VQI A;  3ICX A;  2KBZ A;  4F5V A;  3NVI A;  4L9Q A;  4F5U A;  3FWC C;  4K71 A;  3WHR A;  4LUH A;  2VDB A;  2VUE A;  5DBY A;  2BXG A;  2QM6 A;  2E0Y A;  1LOT A;  3SQJ A;  3CX9 A;  4ZC6 A;  3A75 A;  2BX8 A;  1E78 A;  4Z9O A;  2KWF A;  4WA6 B;  1AO6 A;  2DBW A;  4GDX A;  4FK5 B;  5BPK A;  1MIV A;  4E99 A;  1J78 A;  2JUH A;  5IJE A;  2OZB B;  2DYO A;  3JQZ A;  4J2V A;  2XVW A;  5ID7 A;  5D7G A;  5IJ5 A;  3TDL A;  4PO0 A;  4F5T A;  4I9O A;  1GNI A;  5B5T A;  2I30 A;  4GDL B;  4GDK B;  2XVV A;  3UIV A;  3A73 A;  1MUH A;  1MIY A;  1TXU A;  2Z8I A;  3W1S A;  3FNM A;  3WHQ A;  3NVK A;  1J7E A;  4IW1 A;  4S1Y A;  2BXD A;  1HK4 A;  1GNJ A;  2AGH B;  2VUF A;  2NNW A;  5HOZ A;  5IIX A;  1KDX A;  2BXK A;  3JRY A;  2ROH A;  2EFD A;  1BJ5 A;  1E7E A;  1E7F A;  4K2C A;  2OT3 A;  4ZBK A;  4HGK A;  1FOU A;  3FWB C;  2LOQ A;  1HK1 A;  2QHB A;  4LB9 A;  3V03 A;  3NMU A;  5FUO A;  1JNB A;  2YDF A;  4G03 A;  3V08 A;  4DM0 A;  2DBU A;  4JK4 A;  2QMC A;  4OT2 A;  3LU8 A;  3GQU A;  2LQH A;  4N3Z A;  3LU7 A;  1UOR A;  4G04 A;  1MM8 A;  1MIW A;  4G01 A;  3KJL A;  1H5W A;  4MBE C;  4LUF A;  2E0X A;  5DQF A;  1E7A A;  5ID9 A;  1E7G A;  3KIK A;  1KW2 A;  2BXL A;  2BXB A;  4OTT A;  2XW0 A;  4IW2 A;  1H9Z A;  1HA2 A;  4FIP B;  4M70 B;  4LB2 A;  1VZS A;  3GA9 L;  4BKE A; 
#chains in the Genus database with same CATH homology
 5IIU A;  4OTU A;  5GIN A;  1HK3 A;  3B9M A;  4ZUX V;  2AJE A;  2DG5 A;  4N0U D;  1N5U A;  1BM0 A;  2BXA A;  2XW1 A;  4ZBR A;  4Z69 A;  1VFI A;  3G9K D;  3NVM A;  4LA0 A;  4N0F D;  5IIH A;  1O9X A;  2Z8K A;  3SIV B;  1LNS A;  4HGM B;  1E7C A;  3SIU B;  1BKE A;  4ZCG A;  3M99 C;  3GQX A;  5IJF A;  4EMX A;  1MA9 A;  3MHH B;  3MHS B;  5GHK A;  1E7I A;  4L9K A;  2BXQ A;  2BXH A;  2EFH A;  2XVQ A;  2BXI A;  4ZBQ A;  3B9L A;  4DHX B;  4F5S A;  2DBX A;  1E7B A;  5IFO A;  1HK5 A;  4NAW B;  4BY9 C;  1E7H A;  2V36 A;  4GG2 A;  3V09 A;  1KXP D;  1TF0 A;  3H37 A;  5GIO A;  4L8U A;  2Z8J A;  1NT2 B;  3PLA A;  2XMO A;  2EFC A;  1HK2 A;  3WHS A;  2XSI A;  3LU6 A;  2DYM A;  5GIP A;  2BXN A;  2NQO A;  2BXM A;  2BXF A;  4C31 B;  4OR0 A;  1IJG A;  2BXP A;  4TQ1 A;  2EFE A;  3H3A A;  2BXO A;  4FJC B;  2BXE A;  2BXC A;  2CKX A;  2I2Z A;  4TQ0 A;  4W4U B;  2XVU A;  3VQI A;  3ICX A;  2KBZ A;  4F5V A;  3NVI A;  4L9Q A;  4F5U A;  3FWC C;  4K71 A;  3WHR A;  4LUH A;  2VDB A;  2VUE A;  5DBY A;  2BXG A;  2QM6 A;  2E0Y A;  1LOT A;  3SQJ A;  3CX9 A;  4ZC6 A;  3A75 A;  2BX8 A;  1E78 A;  4Z9O A;  4WA6 B;  1AO6 A;  2DBW A;  4GDX A;  4FK5 B;  5BPK A;  1MIV A;  4E99 A;  1J78 A;  2JUH A;  5IJE A;  2OZB B;  2DYO A;  3JQZ A;  4J2V A;  2XVW A;  5ID7 A;  5D7G A;  5IJ5 A;  3TDL A;  4PO0 A;  4F5T A;  1GNI A;  5B5T A;  2I30 A;  4GDL B;  4GDK B;  2XVV A;  3UIV A;  3A73 A;  1MIY A;  1TXU A;  2Z8I A;  3W1S A;  3FNM A;  3WHQ A;  3NVK A;  1J7E A;  4IW1 A;  4S1Y A;  2BXD A;  1HK4 A;  1GNJ A;  2VUF A;  2NNW A;  5HOZ A;  5IIX A;  2BXK A;  3JRY A;  2ROH A;  2EFD A;  1BJ5 A;  1E7E A;  1E7F A;  4K2C A;  2OT3 A;  4ZBK A;  4HGK A;  1FOU A;  3FWB C;  2LOQ A;  1HK1 A;  2QHB A;  4LB9 A;  3V03 A;  3NMU A;  5FUO A;  1JNB A;  2YDF A;  4G03 A;  3V08 A;  2DBU A;  4JK4 A;  2QMC A;  4OT2 A;  3LU8 A;  3GQU A;  4N3Z A;  3LU7 A;  1UOR A;  4G04 A;  1MIW A;  4G01 A;  3KJL A;  1H5W A;  4MBE C;  4LUF A;  2E0X A;  5DQF A;  1E7A A;  5ID9 A;  1E7G A;  3KIK A;  1KW2 A;  2BXL A;  2BXB A;  4OTT A;  2XW0 A;  4IW2 A;  1H9Z A;  1HA2 A;  4FIP B;  4M70 B;  4LB2 A;  1VZS A;  3GA9 L;  4BKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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