4LA0A

X-ray study of human serum albumin complexed with bicalutamide
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
581
structure length
581
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural studies of several clinically important oncology drugs in complex with human serum albumin.
pubmed doi rcsb
molecule keywords SERUM ALBUMIN
molecule tags Transport protein
total genus 226
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A05
2I30A 4F5TA 1E7CA 5DBYA 3A73A 2BX8A 4K71A 1E7EA 4N0UD 5FUOA 4G04A 4Z69A 4JK4A 1J78A 4G03A 4L9KA 2BXIA 2I2ZA 2BXHA 3B9LA 2BXLA 4J2VA 5DQFA 2XVQA 1AO6A 2BXNA 1E7AA 4L9QA 3TDLA 5IJFA 4S1YA 4F5UA 1HK4A 1LOTA 2YDFA 4N0FD 5IJEA 3SQJA 1UORA 2BXOA 1HK2A 2BXEA 1KXPD 4HGKA 2BXGA 1BM0A 1GNIA 1BJ5A 2BXMA 2XVWA 4ZBRA 3V08A 2VDBA 4ZBQA 3JQZA 2XSIA 4LB9A 2VUEA 4E99A 3V09A 3V03A 1KW2A 2XVVA 1E7GA 4LUFA 1HK1A 1TF0A 1E7HA 5IIUA 4LA0A 1E7IA 2BXCA 1MA9A 1E7BA 2BXKA 2BXFA 2BXAA 1GNJA 2BXPA 4EMXA 1O9XA 5IFOA 1BKEA 1E7FA 4OT2A 4K2CA 2BXDA 3LU8A 1HK3A 3LU7A 5HOZA 5ID7A 2XW0A 1H9ZA 1N5UA 2XW1A 4OR0A 4L8UA 3B9MA 5GHKA 3LU6A 2VUFA 4F5SA 5IJ5A 4F5VA 5ID9A 3CX9A 3JRYA 5IIHA 2BXQA 1HA2A 4HGMB 4LB2A 5IIXA 1E78A 4LUHA 2XVUA 4PO0A 2BXBA 1J7EA 4IW2A 1HK5A 3UIVA 4BKEA 4IW1A
chains in the Genus database with same CATH superfamily
2I30A 2LXSA 2KWFA 2DBWA 4F5TA 1E7CA 5DBYA 3A73A 2BX8A 1KDXA 3WHSA 4K71A 1E7EA 4N0UD 1MIVA 3GA9L 5FUOA 4FK5B 4G04A 1H5WA 4NAWB 4Z69A 4JK4A 1J78A 4G03A 4L9KA 2JUHA 3KIKA 3NVIA 2BXIA 2LQIA 2I2ZA 2BXHA 2ROHA 2BXLA 3B9LA 4J2VA 5DQFA 1MUHA 1MIWA 3MHSB 2EFCA 2XVQA 1AO6A 5B5TA 2BXNA 2Z8KA 1E7AA 2DYMA 4L9QA 3TDLA 5IJFA 4MBEC 4S1YA 1MUSA 4F5UA 2LXTA 1HK4A 1LOTA 2YDFA 4N0FD 5IJEA 3ICXA 3SQJA 1UORA 2BXOA 2AJEA 1HK2A 3MHHB 4DHXB 2BXEA 4C31B 1KXPD 3VQIA 1TXUA 4HGKA 2V36A 2BXGA 1BM0A 1GNIA 1BJ5A 1VFIA 4M70B 3NVKA 4WA6B 3G9KD 4N3ZA 2BXMA 2K0NA 2EFHA 4ZUXV 1FOUA 2DBXA 4OTTA 1VZSA 2XVWA 3M99C 1NT2B 2DBUA 4ZBRA 3V08A 2DYOA 2VDBA 3FWCC 5GIPA 4ZBQA 1MIYA 3JQZA 4GDKB 2XSIA 2E0XA 4G01A 4LB9A 2E0YA 2VUEA 3WHQA 2CKXA 4E99A 3V09A 3V03A 1KW2A 5D7GA 2XVVA 1E7GA 4LUFA 3BPJA 3NMUA 4FJCB 1HK1A 1TF0A 1E7HA 4TQ0A 5IIUA 2Z8IA 1E7IA 4GDLB 4GDXA 4LA0A 3WHRA 2DG5A 2BXCA 1MA9A 2EFDA 1E7BA 4ZCGA 2BXKA 2BXFA 2BXAA 1GNJA 3FNMA 2BXPA 1SB0A 4TQ1A 4EMXA 1IJGA 1O9XA 2NNWA 5IFOA 1BKEA 5GIOA 1E7FA 3NVMA 4OT2A 4K2CA 4Z9OA 2BXDA 4D7XA 2QHBA 4OTUA 3W1SA 3GQUA 3ECPA 3LU8A 4W4UB 4ZC6A 1HK3A 2OZBB 3LU7A 3PLAA 3SIUB 5HOZA 5ID7A 5BPKA 2XW0A 1H9ZA 2NQOA 2GUTA 3GQXA 1N5UA 2XW1A 4OR0A 3KJLA 1MM8A 4FIPB 3H37A 4L8UA 4ZBKA 3SIVB 2LOQA 3B9MA 2QM6A 5GHKA 3LU6A 2VUFA 2XMOA 5GINA 2LQHA 3H3AA 2OT3A 4F5SA 5IJ5A 2Z8JA 4BY9C 2EFEA 4F5VA 1JNBA 5ID9A 3CX9A 3JRYA 5IIHA 1LNSA 2BXQA 1HA2A 2QMCA 4HGMB 4GG2A 4LB2A 5IIXA 2AGHB 1E78A 4I9OA 2KBZA 4LUHA 2XVUA 4DM0A 4PO0A 2BXBA 1J7EA 3A75A 4IW2A 1HK5A 3UIVA 4BKEA 4IW1A 3FWBC
chains in the Genus database with same CATH topology
2I30A 2DBWA 4F5TA 1E7CA 5DBYA 3A73A 2BX8A 3WHSA 4K71A 1E7EA 4N0UD 1MIVA 3GA9L 5FUOA 4FK5B 4G04A 1H5WA 4NAWB 4Z69A 4JK4A 1J78A 4G03A 4L9KA 2JUHA 3KIKA 3NVIA 2BXIA 2I2ZA 2BXHA 2ROHA 2BXLA 3B9LA 4J2VA 5DQFA 1MIWA 3MHSB 2EFCA 2XVQA 1AO6A 5B5TA 2BXNA 2Z8KA 1E7AA 2DYMA 4L9QA 3TDLA 5IJFA 4MBEC 4S1YA 4F5UA 1HK4A 1LOTA 2YDFA 4N0FD 5IJEA 3ICXA 3SQJA 1UORA 2BXOA 2AJEA 1HK2A 3MHHB 4DHXB 2BXEA 4C31B 1KXPD 3VQIA 1TXUA 4HGKA 2V36A 2BXGA 1BM0A 1GNIA 1BJ5A 1VFIA 4M70B 3NVKA 4WA6B 3G9KD 4N3ZA 2BXMA 2EFHA 4ZUXV 1FOUA 2DBXA 4OTTA 1VZSA 2XVWA 3M99C 1NT2B 2DBUA 4ZBRA 3V08A 2DYOA 2VDBA 3FWCC 5GIPA 4ZBQA 1MIYA 3JQZA 4GDKB 2XSIA 2E0XA 4G01A 4LB9A 2E0YA 2VUEA 3WHQA 2CKXA 4E99A 3V09A 3V03A 1KW2A 5D7GA 2XVVA 1E7GA 4LUFA 3NMUA 4FJCB 1HK1A 1TF0A 1E7HA 4TQ0A 5IIUA 2Z8IA 1E7IA 4GDLB 4GDXA 4LA0A 3WHRA 2DG5A 2BXCA 1MA9A 2EFDA 1E7BA 4ZCGA 2BXKA 2BXFA 2BXAA 1GNJA 3FNMA 2BXPA 4EMXA 4TQ1A 1IJGA 1O9XA 2NNWA 5IFOA 1BKEA 5GIOA 1E7FA 3NVMA 4OT2A 4K2CA 4Z9OA 2BXDA 2QHBA 4OTUA 3W1SA 3GQUA 3LU8A 4W4UB 4ZC6A 1HK3A 2OZBB 3LU7A 3PLAA 3SIUB 5HOZA 5ID7A 5BPKA 2XW0A 1H9ZA 2NQOA 3GQXA 1N5UA 2XW1A 4OR0A 3KJLA 4FIPB 3H37A 4L8UA 4ZBKA 3SIVB 2LOQA 3B9MA 2QM6A 5GHKA 3LU6A 2VUFA 2XMOA 5GINA 3H3AA 2OT3A 4F5SA 5IJ5A 2Z8JA 4BY9C 2EFEA 4F5VA 1JNBA 5ID9A 3CX9A 3JRYA 5IIHA 1LNSA 2BXQA 1HA2A 2QMCA 4HGMB 4GG2A 4LB2A 5IIXA 1E78A 2KBZA 4LUHA 2XVUA 4PO0A 2BXBA 1J7EA 3A75A 4IW2A 1HK5A 3UIVA 4BKEA 4IW1A 3FWBC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I30 A;  4F5T A;  1E7C A;  5DBY A;  3A73 A;  2BX8 A;  4K71 A;  1E7E A;  4N0U D;  5FUO A;  4G04 A;  4Z69 A;  4JK4 A;  1J78 A;  4G03 A;  4L9K A;  2BXI A;  2I2Z A;  2BXH A;  3B9L A;  2BXL A;  4J2V A;  5DQF A;  2XVQ A;  1AO6 A;  2BXN A;  1E7A A;  4L9Q A;  3TDL A;  5IJF A;  4S1Y A;  4F5U A;  1HK4 A;  1LOT A;  2YDF A;  4N0F D;  5IJE A;  3SQJ A;  1UOR A;  2BXO A;  1HK2 A;  2BXE A;  1KXP D;  4HGK A;  2BXG A;  1BM0 A;  1GNI A;  1BJ5 A;  2BXM A;  2XVW A;  4ZBR A;  3V08 A;  2VDB A;  4ZBQ A;  3JQZ A;  2XSI A;  4LB9 A;  2VUE A;  4E99 A;  3V09 A;  3V03 A;  1KW2 A;  2XVV A;  1E7G A;  4LUF A;  1HK1 A;  1TF0 A;  1E7H A;  5IIU A;  4LA0 A;  1E7I A;  2BXC A;  1MA9 A;  1E7B A;  2BXK A;  2BXF A;  2BXA A;  1GNJ A;  2BXP A;  4EMX A;  1O9X A;  5IFO A;  1BKE A;  1E7F A;  4OT2 A;  4K2C A;  2BXD A;  3LU8 A;  1HK3 A;  3LU7 A;  5HOZ A;  5ID7 A;  2XW0 A;  1H9Z A;  1N5U A;  2XW1 A;  4OR0 A;  4L8U A;  3B9M A;  5GHK A;  3LU6 A;  2VUF A;  4F5S A;  5IJ5 A;  4F5V A;  5ID9 A;  3CX9 A;  3JRY A;  5IIH A;  2BXQ A;  1HA2 A;  4HGM B;  4LB2 A;  5IIX A;  1E78 A;  4LUH A;  2XVU A;  4PO0 A;  2BXB A;  1J7E A;  4IW2 A;  1HK5 A;  3UIV A;  4BKE A;  4IW1 A; 
#chains in the Genus database with same CATH topology
 2I30 A;  2LXS A;  2KWF A;  2DBW A;  4F5T A;  1E7C A;  5DBY A;  3A73 A;  2BX8 A;  1KDX A;  3WHS A;  4K71 A;  1E7E A;  4N0U D;  1MIV A;  3GA9 L;  5FUO A;  4FK5 B;  4G04 A;  1H5W A;  4NAW B;  4Z69 A;  4JK4 A;  1J78 A;  4G03 A;  4L9K A;  2JUH A;  3KIK A;  3NVI A;  2BXI A;  2LQI A;  2I2Z A;  2BXH A;  2ROH A;  2BXL A;  3B9L A;  4J2V A;  5DQF A;  1MUH A;  1MIW A;  3MHS B;  2EFC A;  2XVQ A;  1AO6 A;  5B5T A;  2BXN A;  2Z8K A;  1E7A A;  2DYM A;  4L9Q A;  3TDL A;  5IJF A;  4MBE C;  4S1Y A;  1MUS A;  4F5U A;  2LXT A;  1HK4 A;  1LOT A;  2YDF A;  4N0F D;  5IJE A;  3ICX A;  3SQJ A;  1UOR A;  2BXO A;  2AJE A;  1HK2 A;  3MHH B;  4DHX B;  2BXE A;  4C31 B;  1KXP D;  3VQI A;  1TXU A;  4HGK A;  2V36 A;  2BXG A;  1BM0 A;  1GNI A;  1BJ5 A;  1VFI A;  4M70 B;  3NVK A;  4WA6 B;  3G9K D;  4N3Z A;  2BXM A;  2K0N A;  2EFH A;  4ZUX V;  1FOU A;  2DBX A;  4OTT A;  1VZS A;  2XVW A;  3M99 C;  1NT2 B;  2DBU A;  4ZBR A;  3V08 A;  2DYO A;  2VDB A;  3FWC C;  5GIP A;  4ZBQ A;  1MIY A;  3JQZ A;  4GDK B;  2XSI A;  2E0X A;  4G01 A;  4LB9 A;  2E0Y A;  2VUE A;  3WHQ A;  2CKX A;  4E99 A;  3V09 A;  3V03 A;  1KW2 A;  5D7G A;  2XVV A;  1E7G A;  4LUF A;  3BPJ A;  3NMU A;  4FJC B;  1HK1 A;  1TF0 A;  1E7H A;  4TQ0 A;  5IIU A;  2Z8I A;  1E7I A;  4GDL B;  4GDX A;  4LA0 A;  3WHR A;  2DG5 A;  2BXC A;  1MA9 A;  2EFD A;  1E7B A;  4ZCG A;  2BXK A;  2BXF A;  2BXA A;  1GNJ A;  3FNM A;  2BXP A;  1SB0 A;  4TQ1 A;  4EMX A;  1IJG A;  1O9X A;  2NNW A;  5IFO A;  1BKE A;  5GIO A;  1E7F A;  3NVM A;  4OT2 A;  4K2C A;  4Z9O A;  2BXD A;  4D7X A;  2QHB A;  4OTU A;  3W1S A;  3GQU A;  3ECP A;  3LU8 A;  4W4U B;  4ZC6 A;  1HK3 A;  2OZB B;  3LU7 A;  3PLA A;  3SIU B;  5HOZ A;  5ID7 A;  5BPK A;  2XW0 A;  1H9Z A;  2NQO A;  2GUT A;  3GQX A;  1N5U A;  2XW1 A;  4OR0 A;  3KJL A;  1MM8 A;  4FIP B;  3H37 A;  4L8U A;  4ZBK A;  3SIV B;  2LOQ A;  3B9M A;  2QM6 A;  5GHK A;  3LU6 A;  2VUF A;  2XMO A;  5GIN A;  2LQH A;  3H3A A;  2OT3 A;  4F5S A;  5IJ5 A;  2Z8J A;  4BY9 C;  2EFE A;  4F5V A;  1JNB A;  5ID9 A;  3CX9 A;  3JRY A;  5IIH A;  1LNS A;  2BXQ A;  1HA2 A;  2QMC A;  4HGM B;  4GG2 A;  4LB2 A;  5IIX A;  2AGH B;  1E78 A;  4I9O A;  2KBZ A;  4LUH A;  2XVU A;  4DM0 A;  4PO0 A;  2BXB A;  1J7E A;  3A75 A;  4IW2 A;  1HK5 A;  3UIV A;  4BKE A;  4IW1 A;  3FWB C; 
#chains in the Genus database with same CATH homology
 2I30 A;  2DBW A;  4F5T A;  1E7C A;  5DBY A;  3A73 A;  2BX8 A;  3WHS A;  4K71 A;  1E7E A;  4N0U D;  1MIV A;  3GA9 L;  5FUO A;  4FK5 B;  4G04 A;  1H5W A;  4NAW B;  4Z69 A;  4JK4 A;  1J78 A;  4G03 A;  4L9K A;  2JUH A;  3KIK A;  3NVI A;  2BXI A;  2I2Z A;  2BXH A;  2ROH A;  2BXL A;  3B9L A;  4J2V A;  5DQF A;  1MIW A;  3MHS B;  2EFC A;  2XVQ A;  1AO6 A;  5B5T A;  2BXN A;  2Z8K A;  1E7A A;  2DYM A;  4L9Q A;  3TDL A;  5IJF A;  4MBE C;  4S1Y A;  4F5U A;  1HK4 A;  1LOT A;  2YDF A;  4N0F D;  5IJE A;  3ICX A;  3SQJ A;  1UOR A;  2BXO A;  2AJE A;  1HK2 A;  3MHH B;  4DHX B;  2BXE A;  4C31 B;  1KXP D;  3VQI A;  1TXU A;  4HGK A;  2V36 A;  2BXG A;  1BM0 A;  1GNI A;  1BJ5 A;  1VFI A;  4M70 B;  3NVK A;  4WA6 B;  3G9K D;  4N3Z A;  2BXM A;  2EFH A;  4ZUX V;  1FOU A;  2DBX A;  4OTT A;  1VZS A;  2XVW A;  3M99 C;  1NT2 B;  2DBU A;  4ZBR A;  3V08 A;  2DYO A;  2VDB A;  3FWC C;  5GIP A;  4ZBQ A;  1MIY A;  3JQZ A;  4GDK B;  2XSI A;  2E0X A;  4G01 A;  4LB9 A;  2E0Y A;  2VUE A;  3WHQ A;  2CKX A;  4E99 A;  3V09 A;  3V03 A;  1KW2 A;  5D7G A;  2XVV A;  1E7G A;  4LUF A;  3NMU A;  4FJC B;  1HK1 A;  1TF0 A;  1E7H A;  4TQ0 A;  5IIU A;  2Z8I A;  1E7I A;  4GDL B;  4GDX A;  4LA0 A;  3WHR A;  2DG5 A;  2BXC A;  1MA9 A;  2EFD A;  1E7B A;  4ZCG A;  2BXK A;  2BXF A;  2BXA A;  1GNJ A;  3FNM A;  2BXP A;  4EMX A;  4TQ1 A;  1IJG A;  1O9X A;  2NNW A;  5IFO A;  1BKE A;  5GIO A;  1E7F A;  3NVM A;  4OT2 A;  4K2C A;  4Z9O A;  2BXD A;  2QHB A;  4OTU A;  3W1S A;  3GQU A;  3LU8 A;  4W4U B;  4ZC6 A;  1HK3 A;  2OZB B;  3LU7 A;  3PLA A;  3SIU B;  5HOZ A;  5ID7 A;  5BPK A;  2XW0 A;  1H9Z A;  2NQO A;  3GQX A;  1N5U A;  2XW1 A;  4OR0 A;  3KJL A;  4FIP B;  3H37 A;  4L8U A;  4ZBK A;  3SIV B;  2LOQ A;  3B9M A;  2QM6 A;  5GHK A;  3LU6 A;  2VUF A;  2XMO A;  5GIN A;  3H3A A;  2OT3 A;  4F5S A;  5IJ5 A;  2Z8J A;  4BY9 C;  2EFE A;  4F5V A;  1JNB A;  5ID9 A;  3CX9 A;  3JRY A;  5IIH A;  1LNS A;  2BXQ A;  1HA2 A;  2QMC A;  4HGM B;  4GG2 A;  4LB2 A;  5IIX A;  1E78 A;  2KBZ A;  4LUH A;  2XVU A;  4PO0 A;  2BXB A;  1J7E A;  3A75 A;  4IW2 A;  1HK5 A;  3UIV A;  4BKE A;  4IW1 A;  3FWB C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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