4LB2A

X-ray study of human serum albumin complexed with idarubicin
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural studies of several clinically important oncology drugs in complex with human serum albumin.
pubmed doi rcsb
molecule tags Transport protein
total genus 218
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A05
2VUFA 5IJ5A 3JQZA 2YDFA 5IIHA 1E7AA 2BX8A 1E7HA 1HK3A 1TF0A 2BXBA 4LUHA 4G04A 4BKEA 4F5UA 4L9QA 2BXEA 1E7GA 4J2VA 1HA2A 4IW2A 1GNIA 1E7BA 3V03A 1BJ5A 5IJEA 5IIXA 4K71A 5DQFA 1E7EA 2BXGA 3SQJA 2XW1A 5IIUA 1E7CA 4L8UA 4PO0A 2BXDA 1GNJA 5IFOA 1E7FA 1KW2A 5GHKA 2BXHA 5ID7A 2BXFA 4EMXA 1MA9A 4HGMB 4E99A 4LB2A 5IJFA 4F5SA 4IW1A 4LA0A 4LUFA 1J78A 4HGKA 1AO6A 2XSIA 3LU7A 2XW0A 3UIVA 2BXCA 1HK2A 2BXQA 3JRYA 4ZBQA 1UORA 2BXLA 1N5UA 3V09A 4K2CA 1BKEA 1HK1A 4F5VA 3CX9A 4N0FD 4G03A 1KXPD 2BXPA 2BXNA 2XVQA 3LU6A 4ZBRA 2XVUA 5FUOA 1O9XA 2BXIA 3TDLA 4LB9A 1H9ZA 4S1YA 3LU8A 5DBYA 1E78A 2XVVA 4JK4A 2I2ZA 2BXAA 3B9LA 1HK4A 1E7IA 1LOTA 3V08A 2VUEA 2I30A 1J7EA 4L9KA 2BXOA 4OT2A 2BXKA 1HK5A 5ID9A 3A73A 5HOZA 4F5TA 2BXMA 2XVWA 3B9MA 2VDBA 4Z69A 1BM0A 4OR0A 4N0UD
chains in the Genus database with same CATH superfamily
2VUFA 5IJ5A 3JQZA 2YDFA 4Z9OA 5IIHA 1E7AA 1VZSA 1E7HA 1HK3A 1VFIA 2BX8A 1TF0A 2BXBA 2DYOA 2QMCA 2Z8IA 3NVKA 5BPKA 2Z8JA 3WHQA 4WA6B 4LUHA 4G04A 1JNBA 1SB0A 4BKEA 3A75A 4F5UA 2K0NA 3BPJA 4G01A 4L9QA 2BXEA 3NVIA 3NMUA 4DM0A 1E7GA 4J2VA 1HA2A 3GQXA 2OZBB 4IW2A 1GNIA 1E7BA 3V03A 1BJ5A 5IJEA 4TQ1A 5IIXA 2NQOA 4GG2A 4K71A 5DQFA 3FWBC 4FJCB 4D7XA 1E7EA 2BXGA 3SQJA 2XW1A 2DBWA 2EFDA 3M99C 5IIUA 1E7CA 4L8UA 4PO0A 1MM8A 2BXDA 1GNJA 5IFOA 3PLAA 1FOUA 3FWCC 3MHSB 2V36A 4N3ZA 1E7FA 1KW2A 5GHKA 4W4UB 5GINA 2BXHA 2ROHA 5ID7A 3NVMA 2AJEA 3G9KD 2DBXA 4TQ0A 2CKXA 2BXFA 3MHHB 4EMXA 1MIVA 1MA9A 2EFEA 5GIPA 2DBUA 4HGMB 4E99A 4GDKB 2GUTA 4LB2A 5IJFA 4F5SA 4IW1A 4LA0A 4LUFA 3VQIA 4ZC6A 2DG5A 4NAWB 1J78A 3FNMA 1LNSA 1NT2B 4HGKA 1AO6A 2XSIA 4ZBKA 4BY9C 1MUHA 3LU7A 2XW0A 3UIVA 2BXCA 3ICXA 1HK2A 2BXQA 3JRYA 4ZBQA 1UORA 2AGHB 2BXLA 3GQUA 4M70B 3SIVB 2LXSA 4MBEC 2DYMA 1N5UA 5B5TA 1IJGA 3V09A 4K2CA 1BKEA 1HK1A 4F5VA 3CX9A 4ZCGA 4N0FD 4OTUA 4DHXB 4G03A 1KXPD 2BXPA 2QHBA 2BXNA 1H5WA 2Z8KA 2KBZA 2XMOA 2XVQA 4FK5B 4GDLB 3LU6A 3WHRA 2EFHA 1TXUA 3KIKA 4ZBRA 1KDXA 2XVUA 2QM6A 1MUSA 5FUOA 1O9XA 2BXIA 3TDLA 4LB9A 1H9ZA 2E0XA 2NNWA 4S1YA 3LU8A 5DBYA 2KWFA 2LQHA 1E78A 4GDXA 4C31B 2XVVA 2OT3A 4JK4A 2I2ZA 3W1SA 2BXAA 5GIOA 3B9LA 1MIYA 2JUHA 1HK4A 2LXTA 1E7IA 1LOTA 3V08A 2VUEA 3SIUB 2I30A 2E0YA 1J7EA 2LQIA 1MIWA 3H37A 4I9OA 2BXOA 4L9KA 3ECPA 4OT2A 2EFCA 2BXKA 3WHSA 1HK5A 4FIPB 5ID9A 3A73A 5HOZA 4F5TA 2BXMA 2LOQA 2XVWA 3GA9L 3B9MA 3H3AA 2VDBA 5D7GA 4Z69A 3KJLA 4OTTA 1BM0A 4ZUXV 4OR0A 4N0UD
chains in the Genus database with same CATH topology
2VUFA 5IJ5A 3JQZA 2YDFA 4Z9OA 5IIHA 1E7AA 1VZSA 1E7HA 1HK3A 1VFIA 2BX8A 1TF0A 2BXBA 2DYOA 2QMCA 2Z8IA 3NVKA 5BPKA 2Z8JA 3WHQA 4WA6B 4LUHA 4G04A 1JNBA 4BKEA 3A75A 4F5UA 4G01A 3NMUA 4L9QA 2BXEA 3NVIA 1E7GA 4J2VA 1HA2A 3GQXA 2OZBB 4IW2A 1GNIA 1E7BA 3V03A 1BJ5A 5IJEA 4TQ1A 5IIXA 2NQOA 4GG2A 4K71A 5DQFA 3FWBC 4FJCB 1E7EA 2BXGA 3SQJA 2XW1A 2DBWA 2EFDA 3M99C 5IIUA 1E7CA 4L8UA 4PO0A 2BXDA 1GNJA 5IFOA 3PLAA 1FOUA 3FWCC 3MHSB 2V36A 4N3ZA 1E7FA 1KW2A 5GHKA 4W4UB 5GINA 2BXHA 2ROHA 5ID7A 3NVMA 2AJEA 3G9KD 2DBXA 4TQ0A 2CKXA 2BXFA 3MHHB 4EMXA 1MIVA 1MA9A 2EFEA 5GIPA 2DBUA 4HGMB 4E99A 4GDKB 4LB2A 5IJFA 4F5SA 4IW1A 4LA0A 4LUFA 3VQIA 4ZC6A 2DG5A 4NAWB 1J78A 3FNMA 1LNSA 1NT2B 4HGKA 1AO6A 2XSIA 4ZBKA 4BY9C 3LU7A 2XW0A 3UIVA 2BXCA 3ICXA 1HK2A 2BXQA 3JRYA 4ZBQA 1UORA 2BXLA 3GQUA 4M70B 3SIVB 4MBEC 2DYMA 1N5UA 5B5TA 1IJGA 3V09A 4K2CA 1BKEA 1HK1A 4F5VA 3CX9A 4ZCGA 4N0FD 4OTUA 4DHXB 4G03A 1KXPD 2BXPA 2QHBA 2BXNA 1H5WA 2Z8KA 2KBZA 2XMOA 2XVQA 4FK5B 4GDLB 3LU6A 3WHRA 2EFHA 1TXUA 3KIKA 4ZBRA 2XVUA 2QM6A 5FUOA 1O9XA 2BXIA 3TDLA 4LB9A 1H9ZA 2E0XA 2NNWA 4S1YA 3LU8A 5DBYA 1E78A 4GDXA 4C31B 2XVVA 2OT3A 4JK4A 2I2ZA 3W1SA 2BXAA 5GIOA 3B9LA 1MIYA 2JUHA 1HK4A 1E7IA 1LOTA 3V08A 2VUEA 3SIUB 2I30A 2E0YA 1J7EA 1MIWA 3H37A 4L9KA 2BXOA 4OT2A 2EFCA 2BXKA 3WHSA 1HK5A 4FIPB 5ID9A 3A73A 5HOZA 4F5TA 2BXMA 2LOQA 2XVWA 3GA9L 3B9MA 3H3AA 2VDBA 5D7GA 4Z69A 3KJLA 4OTTA 1BM0A 4ZUXV 4OR0A 4N0UD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VUF A;  5IJ5 A;  3JQZ A;  2YDF A;  5IIH A;  1E7A A;  2BX8 A;  1E7H A;  1HK3 A;  1TF0 A;  2BXB A;  4LUH A;  4G04 A;  4BKE A;  4F5U A;  4L9Q A;  2BXE A;  1E7G A;  4J2V A;  1HA2 A;  4IW2 A;  1GNI A;  1E7B A;  3V03 A;  1BJ5 A;  5IJE A;  5IIX A;  4K71 A;  5DQF A;  1E7E A;  2BXG A;  3SQJ A;  2XW1 A;  5IIU A;  1E7C A;  4L8U A;  4PO0 A;  2BXD A;  1GNJ A;  5IFO A;  1E7F A;  1KW2 A;  5GHK A;  2BXH A;  5ID7 A;  2BXF A;  4EMX A;  1MA9 A;  4HGM B;  4E99 A;  4LB2 A;  5IJF A;  4F5S A;  4IW1 A;  4LA0 A;  4LUF A;  1J78 A;  4HGK A;  1AO6 A;  2XSI A;  3LU7 A;  2XW0 A;  3UIV A;  2BXC A;  1HK2 A;  2BXQ A;  3JRY A;  4ZBQ A;  1UOR A;  2BXL A;  1N5U A;  3V09 A;  4K2C A;  1BKE A;  1HK1 A;  4F5V A;  3CX9 A;  4N0F D;  4G03 A;  1KXP D;  2BXP A;  2BXN A;  2XVQ A;  3LU6 A;  4ZBR A;  2XVU A;  5FUO A;  1O9X A;  2BXI A;  3TDL A;  4LB9 A;  1H9Z A;  4S1Y A;  3LU8 A;  5DBY A;  1E78 A;  2XVV A;  4JK4 A;  2I2Z A;  2BXA A;  3B9L A;  1HK4 A;  1E7I A;  1LOT A;  3V08 A;  2VUE A;  2I30 A;  1J7E A;  4L9K A;  2BXO A;  4OT2 A;  2BXK A;  1HK5 A;  5ID9 A;  3A73 A;  5HOZ A;  4F5T A;  2BXM A;  2XVW A;  3B9M A;  2VDB A;  4Z69 A;  1BM0 A;  4OR0 A;  4N0U D; 
#chains in the Genus database with same CATH topology
 2VUF A;  5IJ5 A;  3JQZ A;  2YDF A;  4Z9O A;  5IIH A;  1E7A A;  1VZS A;  1E7H A;  1HK3 A;  1VFI A;  2BX8 A;  1TF0 A;  2BXB A;  2DYO A;  2QMC A;  2Z8I A;  3NVK A;  5BPK A;  2Z8J A;  3WHQ A;  4WA6 B;  4LUH A;  4G04 A;  1JNB A;  1SB0 A;  4BKE A;  3A75 A;  4F5U A;  2K0N A;  3BPJ A;  4G01 A;  4L9Q A;  2BXE A;  3NVI A;  3NMU A;  4DM0 A;  1E7G A;  4J2V A;  1HA2 A;  3GQX A;  2OZB B;  4IW2 A;  1GNI A;  1E7B A;  3V03 A;  1BJ5 A;  5IJE A;  4TQ1 A;  5IIX A;  2NQO A;  4GG2 A;  4K71 A;  5DQF A;  3FWB C;  4FJC B;  4D7X A;  1E7E A;  2BXG A;  3SQJ A;  2XW1 A;  2DBW A;  2EFD A;  3M99 C;  5IIU A;  1E7C A;  4L8U A;  4PO0 A;  1MM8 A;  2BXD A;  1GNJ A;  5IFO A;  3PLA A;  1FOU A;  3FWC C;  3MHS B;  2V36 A;  4N3Z A;  1E7F A;  1KW2 A;  5GHK A;  4W4U B;  5GIN A;  2BXH A;  2ROH A;  5ID7 A;  3NVM A;  2AJE A;  3G9K D;  2DBX A;  4TQ0 A;  2CKX A;  2BXF A;  3MHH B;  4EMX A;  1MIV A;  1MA9 A;  2EFE A;  5GIP A;  2DBU A;  4HGM B;  4E99 A;  4GDK B;  2GUT A;  4LB2 A;  5IJF A;  4F5S A;  4IW1 A;  4LA0 A;  4LUF A;  3VQI A;  4ZC6 A;  2DG5 A;  4NAW B;  1J78 A;  3FNM A;  1LNS A;  1NT2 B;  4HGK A;  1AO6 A;  2XSI A;  4ZBK A;  4BY9 C;  1MUH A;  3LU7 A;  2XW0 A;  3UIV A;  2BXC A;  3ICX A;  1HK2 A;  2BXQ A;  3JRY A;  4ZBQ A;  1UOR A;  2AGH B;  2BXL A;  3GQU A;  4M70 B;  3SIV B;  2LXS A;  4MBE C;  2DYM A;  1N5U A;  5B5T A;  1IJG A;  3V09 A;  4K2C A;  1BKE A;  1HK1 A;  4F5V A;  3CX9 A;  4ZCG A;  4N0F D;  4OTU A;  4DHX B;  4G03 A;  1KXP D;  2BXP A;  2QHB A;  2BXN A;  1H5W A;  2Z8K A;  2KBZ A;  2XMO A;  2XVQ A;  4FK5 B;  4GDL B;  3LU6 A;  3WHR A;  2EFH A;  1TXU A;  3KIK A;  4ZBR A;  1KDX A;  2XVU A;  2QM6 A;  1MUS A;  5FUO A;  1O9X A;  2BXI A;  3TDL A;  4LB9 A;  1H9Z A;  2E0X A;  2NNW A;  4S1Y A;  3LU8 A;  5DBY A;  2KWF A;  2LQH A;  1E78 A;  4GDX A;  4C31 B;  2XVV A;  2OT3 A;  4JK4 A;  2I2Z A;  3W1S A;  2BXA A;  5GIO A;  3B9L A;  1MIY A;  2JUH A;  1HK4 A;  2LXT A;  1E7I A;  1LOT A;  3V08 A;  2VUE A;  3SIU B;  2I30 A;  2E0Y A;  1J7E A;  2LQI A;  1MIW A;  3H37 A;  4I9O A;  2BXO A;  4L9K A;  3ECP A;  4OT2 A;  2EFC A;  2BXK A;  3WHS A;  1HK5 A;  4FIP B;  5ID9 A;  3A73 A;  5HOZ A;  4F5T A;  2BXM A;  2LOQ A;  2XVW A;  3GA9 L;  3B9M A;  3H3A A;  2VDB A;  5D7G A;  4Z69 A;  3KJL A;  4OTT A;  1BM0 A;  4ZUX V;  4OR0 A;  4N0U D; 
#chains in the Genus database with same CATH homology
 2VUF A;  5IJ5 A;  3JQZ A;  2YDF A;  4Z9O A;  5IIH A;  1E7A A;  1VZS A;  1E7H A;  1HK3 A;  1VFI A;  2BX8 A;  1TF0 A;  2BXB A;  2DYO A;  2QMC A;  2Z8I A;  3NVK A;  5BPK A;  2Z8J A;  3WHQ A;  4WA6 B;  4LUH A;  4G04 A;  1JNB A;  4BKE A;  3A75 A;  4F5U A;  4G01 A;  3NMU A;  4L9Q A;  2BXE A;  3NVI A;  1E7G A;  4J2V A;  1HA2 A;  3GQX A;  2OZB B;  4IW2 A;  1GNI A;  1E7B A;  3V03 A;  1BJ5 A;  5IJE A;  4TQ1 A;  5IIX A;  2NQO A;  4GG2 A;  4K71 A;  5DQF A;  3FWB C;  4FJC B;  1E7E A;  2BXG A;  3SQJ A;  2XW1 A;  2DBW A;  2EFD A;  3M99 C;  5IIU A;  1E7C A;  4L8U A;  4PO0 A;  2BXD A;  1GNJ A;  5IFO A;  3PLA A;  1FOU A;  3FWC C;  3MHS B;  2V36 A;  4N3Z A;  1E7F A;  1KW2 A;  5GHK A;  4W4U B;  5GIN A;  2BXH A;  2ROH A;  5ID7 A;  3NVM A;  2AJE A;  3G9K D;  2DBX A;  4TQ0 A;  2CKX A;  2BXF A;  3MHH B;  4EMX A;  1MIV A;  1MA9 A;  2EFE A;  5GIP A;  2DBU A;  4HGM B;  4E99 A;  4GDK B;  4LB2 A;  5IJF A;  4F5S A;  4IW1 A;  4LA0 A;  4LUF A;  3VQI A;  4ZC6 A;  2DG5 A;  4NAW B;  1J78 A;  3FNM A;  1LNS A;  1NT2 B;  4HGK A;  1AO6 A;  2XSI A;  4ZBK A;  4BY9 C;  3LU7 A;  2XW0 A;  3UIV A;  2BXC A;  3ICX A;  1HK2 A;  2BXQ A;  3JRY A;  4ZBQ A;  1UOR A;  2BXL A;  3GQU A;  4M70 B;  3SIV B;  4MBE C;  2DYM A;  1N5U A;  5B5T A;  1IJG A;  3V09 A;  4K2C A;  1BKE A;  1HK1 A;  4F5V A;  3CX9 A;  4ZCG A;  4N0F D;  4OTU A;  4DHX B;  4G03 A;  1KXP D;  2BXP A;  2QHB A;  2BXN A;  1H5W A;  2Z8K A;  2KBZ A;  2XMO A;  2XVQ A;  4FK5 B;  4GDL B;  3LU6 A;  3WHR A;  2EFH A;  1TXU A;  3KIK A;  4ZBR A;  2XVU A;  2QM6 A;  5FUO A;  1O9X A;  2BXI A;  3TDL A;  4LB9 A;  1H9Z A;  2E0X A;  2NNW A;  4S1Y A;  3LU8 A;  5DBY A;  1E78 A;  4GDX A;  4C31 B;  2XVV A;  2OT3 A;  4JK4 A;  2I2Z A;  3W1S A;  2BXA A;  5GIO A;  3B9L A;  1MIY A;  2JUH A;  1HK4 A;  1E7I A;  1LOT A;  3V08 A;  2VUE A;  3SIU B;  2I30 A;  2E0Y A;  1J7E A;  1MIW A;  3H37 A;  4L9K A;  2BXO A;  4OT2 A;  2EFC A;  2BXK A;  3WHS A;  1HK5 A;  4FIP B;  5ID9 A;  3A73 A;  5HOZ A;  4F5T A;  2BXM A;  2LOQ A;  2XVW A;  3GA9 L;  3B9M A;  3H3A A;  2VDB A;  5D7G A;  4Z69 A;  3KJL A;  4OTT A;  1BM0 A;  4ZUX V;  4OR0 A;  4N0U D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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