4LILA

Crystal structure of the catalytic subunit of human primase bound to utp and mn
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
380
structure length
370
Chain Sequence
PTELPELLKLYYRRLFPYSQYYRWLNYIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSDICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDATRDYKKTSLAPYVKVFEHFLENLDKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA primase small subunit
publication title Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
pubmed doi rcsb
source organism Homo sapiens
total genus 126
structure length 370
sequence length 380
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01896 DNA_primase_S DNA primase small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.920.30 Alpha Beta Alpha-Beta Complex DNA primase, PRIM domain DNA primase, PRIM domain 4lilA00
4LIMA 4BPXA 4MM2A 4LILA 2FARA 4LIKA 4BPWA 4BPUA 4RR2A 4MHQA 2FAOA 5EXRA 1ZT2A 2FAQA
chains in the Genus database with same CATH superfamily
4LIMA 1V33A 1G71A 4BPXA 4MM2A 4LILA 2FARA 4LIKA 4BPWA 4BPUA 4RR2A 5EXRA 4MHQA 2FAOA 1V34A 2ATZA 1ZT2A 2FAQA
chains in the Genus database with same CATH topology
4LIMA 1V33A 1G71A 4BPXA 4MM2A 4LILA 2FARA 4LIKA 4BPWA 4BPUA 4RR2A 5EXRA 4MHQA 2FAOA 1V34A 1ZT2A 2FAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LIM A;  4BPX A;  4MM2 A;  4LIL A;  2FAR A;  4LIK A;  4BPW A;  4BPU A;  4RR2 A;  4MHQ A;  2FAO A;  5EXR A;  1ZT2 A;  2FAQ A; 
#chains in the Genus database with same CATH topology
 4LIM A;  1V33 A;  1G71 A;  4BPX A;  4MM2 A;  4LIL A;  2FAR A;  4LIK A;  4BPW A;  4BPU A;  4RR2 A;  5EXR A;  4MHQ A;  2FAO A;  1V34 A;  2ATZ A;  1ZT2 A;  2FAQ A; 
#chains in the Genus database with same CATH homology
 4LIM A;  1V33 A;  1G71 A;  4BPX A;  4MM2 A;  4LIL A;  2FAR A;  4LIK A;  4BPW A;  4BPU A;  4RR2 A;  5EXR A;  4MHQ A;  2FAO A;  1V34 A;  1ZT2 A;  2FAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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