4LILA

Crystal structure of the catalytic subunit of human primase bound to utp and mn
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
380
structure length
370
Chain Sequence
PTELPELLKLYYRRLFPYSQYYRWLNYIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSDICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDATRDYKKTSLAPYVKVFEHFLENLDKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords DNA primase small subunit
total genus 126
structure length 370
sequence length 380
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01896 DNA_primase_S DNA primase small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.920.30 Alpha Beta Alpha-Beta Complex DNA primase, PRIM domain DNA primase, PRIM domain 4lilA00
2FARA 4MM2A 4RR2A 4BPUA 4LILA 4LIKA 5EXRA 1ZT2A 4BPXA 4BPWA 2FAQA 2FAOA 4LIMA 4MHQA
chains in the Genus database with same CATH superfamily
2FARA 4MM2A 4RR2A 1G71A 4BPUA 4LILA 4LIKA 5EXRA 1ZT2A 4BPXA 1V33A 4BPWA 2FAQA 1V34A 2FAOA 2ATZA 4LIMA 4MHQA
chains in the Genus database with same CATH topology
2FARA 4MM2A 4RR2A 1G71A 4BPUA 4LILA 4LIKA 5EXRA 1ZT2A 4BPXA 1V33A 4BPWA 2FAQA 1V34A 2FAOA 4LIMA 4MHQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FAR A;  4MM2 A;  4RR2 A;  4BPU A;  4LIL A;  4LIK A;  5EXR A;  1ZT2 A;  4BPX A;  4BPW A;  2FAQ A;  2FAO A;  4LIM A;  4MHQ A; 
#chains in the Genus database with same CATH topology
 2FAR A;  4MM2 A;  4RR2 A;  1G71 A;  4BPU A;  4LIL A;  4LIK A;  5EXR A;  1ZT2 A;  4BPX A;  1V33 A;  4BPW A;  2FAQ A;  1V34 A;  2FAO A;  2ATZ A;  4LIM A;  4MHQ A; 
#chains in the Genus database with same CATH homology
 2FAR A;  4MM2 A;  4RR2 A;  1G71 A;  4BPU A;  4LIL A;  4LIK A;  5EXR A;  1ZT2 A;  4BPX A;  1V33 A;  4BPW A;  2FAQ A;  1V34 A;  2FAO A;  4LIM A;  4MHQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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