4LK1A

Crystal structure analysis of the e.coli holoenzyme
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 40
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-07-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4lk1A02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4lk1A01
1Y1WC 4AYBL 2Y0SL 1SFOK 3S1RK 3HOYK 4OINA 4A3BC 4NOIA 3WODA 3HOWC 2WB1L 2JA6C 4C3HC 5C4XK 4A3KK 4A3LC 2NVXC 4A93K 3K7AC 3RZOK 3HKZD 4QJVB 4C3IC 4KN4A 1IW7A 2R92K 3S1RC 4G7HA 1I3QC 4QIWL 3PO3K 4BY1C 2E2IK 3PO2K 4BXXK 4A3MC 3M4OC 5IP9C 2O5JA 5IYBC 4XLPA 2JA7K 2WAQL 3S1MK 2JA8C 3PO3C 2PA8L 3M3YK 4Q4ZA 4BBSC 1HQMA 5M5XK 4BY1K 5C4JK 4Y52C 4BXXC 5IP9K 4XLNA 4MEXA 3HOUC 4KN7A 5M5YK 1TWAC 3GTOC 3H0GK 4BBRK 3GTKK 4Q5SA 3S14K 2E2JC 4A3DC 5C3EK 5IYCK 3GTMC 2E2HC 4A3FC 2R93C 2NVQC 3I4NC 1K83C 3HOXC 3S1QK 3I4MC 4LK0A 1TWAK 2A6EA 1BDFA 2PA8D 2VUMC 2WB1D 2A69A 1YNNA 2WAQD 1SFOC 3HOYC 4C3JK 2NVYK 4A3KC 5M3MK 2JA6K 3S2DK 4ZH4A 4A93C 4A3BK 1Y1VC 3RZDC 3DXJA 1WCMK 4AYBD 3S1QC 3GTLC 4G7OA 2PMZL 4QIWD 3S16K 3RZOC 3K7AK 1TWCK 4C3JC 5TMCA 5C44K 1I50C 2PMZD 3HKZL 4OIQA 2B63K 3CQZC 3EQLA 3S1NK 2JA5K 4QJVA 3M4OK 4XSXA 5M3FK 3GTLK 1R9TK 3S2HK 5D4DA 2JA8K 2JA7C 3S15C 1TWGC 4G7ZA 3S1MC 5IYBK 3GTOK 3HOZK 2B63C 5IYDK 4KMUA 4YFXA 4A3IK 2R7ZK 4Y7NC 3GTJC 3H3VL 5IP7K 4A3CC 4JK1A 4A3GK 2YU9K 4Y52K 2R92C 3HOUK 1TWHK 2NVTC 3S17C 4C2MC 1Y1WK 3GTKC 2E2HK 4OIOA 4A3DK 2O5IA 3HOWK 2YU9C 4OIPA 3I4MK 4BY7K 2NVQK 4YFKA 3I4NK 2NVTK 3S17K 3FKIK 4YG2A 3GTQK 1SMYA 5FLMC 3S2DC 3HOVK 2NVYC 4A3EK 3S16C 4XSZA 5TMFA 4BY7C 1TWFK 2Y0SD 1TWCC 3H0GC 1ZYRA 3GTQC 3HOVC 4A3JK 1I6HC 5C3EC 5C44C 3GTMK 4A3EC 5C4JC 2PPBA 1K83K 3HOXK 2VUMK 3GTPK 4A3LK 4A3JC 4C3IK 1I6HK 4BBRC 5IYDC 3HOZC 3S14C 4YFNA 3S15K 1I3QK 4LLGA 2E2IC 3PO2C 4LK1A 3GTPC 4Y7NK 3GTJK 5IP7C 4A3GC 4A3MK 4MEYA 4C2MK 4BBSK 1I50K 1TWHC 3H3VD 3M3YC 2JA5C 2CW0A 4MQ9A 1WCMC 1XPPA 1Y1VK 2R7ZC 5M5WK 4OIRA 5FJ8K 3RZDK 3FKIC 4LJZA 4X6AK 1TWGK 3GTGC 4GZYA 5FLMK 5IYCC 4A3IC 2E2JK 3S1NC 3CQZK 4A3CK 2A68A 1YNJA 5C4XC 4C3HK 4X6AC 4A3FK 1R9TC 2NVXK 1TWFC 1I6VA 3S2HC 2R93K 3GTGK 2BE5A 2A6HA
chains in the Genus database with same CATH superfamily
2KPUA 3HOYK 3WODA 4XCHA 4QJVB 3S1RC 3PO3K 4QIWL 3GTLA 3TTGA 4BY1C 1TWHA 1I3QA 4BXXK 5IYBC 3S1MK 3CF5S 2XCOA 4G0WA 3M3YK 1HQMA 5M5XK 4BKWA 5IOQA 4PAAA 4KMDA 4MEXA 3HOUC 4P5BA 1K83A 3SZZA 3GTOC 3GIRA 1WORA 5C3EK 4A3FC 4RMFA 1K83C 2PA8D 2VUMC 4C3JK 3HOYC 1WQHA 2L5NA 5HL7S 4WF9S 3JSTA 3GTLC 1BS2A 4LOWA 3T01A 3HKZL 2B63K 4WFAS 3AD7C 1R9TK 1XZQB 3Q3QA 3S2HK 3OPFA 3S1MC 3S15C 4G7ZA 5IYBK 3HOZK 3AQPA 5HL8A 1TWGA 2FQTA 2ZFZA 5IP7K 3HOUK 2E2IA 3S17C 1Y1WK 5E68A 4OIOA 4A3DK 2O5IA 1VGXA 4BY7K 3A8JA 3FKIK 1I50A 3TFIA 3GTQK 3IPJA 4LR2A 4C45A 4A3EK 3FOEA 5TMFA 3CAGA 1TWCC 5C3EC 5C44C 2P8TA 1F93A 1K83K 1BJTA 4DDQA 1USMA 3HOZC 1TWAA 3S15K 1I3QK 3GEEA 1HI9A 1JVIA 4KMAA 5IP7C 4A3MK 2JA5A 4BBSK 3H3VD 1VH2A 1EK8A 4MQ9A 3RZDK 1XPPA 1WSRA 3DLLS 4GZYA 1ZBSA 5JVGS 1F7UA 4A3IC 4J3NA 2R7ZK 1I6VA 4KM8A 1Y1WC 5DM6S 4A3KK 4C3HC 1J6WA 4IOCS 4WCES 4A93K 3K7AC 3HKZD 5IOTA 3AH5A 4KN4A 1WIHA 1G51A 1I3QC 2JA6A 1V5VA 2GAGC 1O26A 4KASA 3M4OC 2O5JA 3GTQA 1TWFA 3HXAA 3PO3C 2JH3A 2V6TA 1EFWA 4BY1K 3FOFA 3NUHA 4KARA 1TWAC 3H0GK 4G0UA 1WOPA 3GTKK 1GE9A 3GTMC 1F7VA 3I4NC 3G4CA 4P5AA 4A3LC 2WB1D 2WAQD 4GTEA 5EGHA 2NVYK 2JA6K 1IE0A 1X31C 4ZH4A 2ZUFA 3RZDC 4AYBD 4G7OA 4QIWD 3RZOC 1I50C 4OIQA 3CQZC 3S1NK 1XZQA 4QJVA 3M4OK 1EQRA 1ZVUA 2JA8K 1DD5A 2JA7C 4WJ3M 2B63C 2CFAB 4KMUA 1DCOA 3GTJC 1XZPB 4Y52K 2KWAA 4A3CC 4JK1A 4GTDA 5L46A 3GTKC 4WJ4A 2YU9C 4OIPA 2NVQK 3S17K 3BUEA 3HOVK 1SMYA 3S2DC 4KMHA 3S16C 4BY7C 1ZYRA 1EI6A 3S0XA 1TWCA 2R7ZA 3HOXK 2YU9A 4A3LK 3PIOS 4C3IK 1J6XA 1I6HK 4BBRC 3GTOA 1PJ6A 4LLGA 3T00A 4LK1A 1XXBA 3L4KA 3GTJK 1B4BA 3L4JA 4MEYA 2EBBA 4WILA 4C2MK 2GSUA 3M3YC 3PIPS 1O24A 5FJ8K 4OIRA 3ERED 4LJZA 3AQOA 2L3UA 5FLMK 4ILDA 4A3CK 2A68A 5C4XC 1IQ0A 4A3FK 4WFNS 2KQ1A 1R9TC 1XZPA 2VUMK 3GTGK 2NVYA 2BE5A 2A6HA 3G4AA 1SFOK 3LAPA 4A3BC 2KXYA 4NOIA 2NVXC 4BLBA 4C3IC 3GTPA 4KB4A 1IW7A 1O2BA 2R92K 2V6UA 1R9TA 1WCMA 3LPXA 3PO2K 4GTLA 3MMLB 3OEPA 4XLPA 2RGRA 2WAQL 4Q4ZA 1O25A 1INNA 4U67S 5HQHA 5IP9K 4XLNA 3GEIA 4GT9A 3TFHA 4BBRK 3S14K 2E2JC 4A3DC 3GEHA 1O2FB 1TWAK 4LK0A 5JVHS 1BDFA 1SFOC 2A69A 1YNNA 2R92A 1PJ7A 1ZXOA 5M3MK 4A3BK 1WCMK 3S1QC 2PMZL 1FEUA 5EGEA 1TWCK 5TMCA 2CFAA 1VLOA 5C44K 1C0AA 3EQLA 2JA5K 1O29A 2ZJQS 4XSXA 2V6SA 5M3FK 1WQGA 3N3YA 5IYDK 1TWGC 4YFXA 4A3IK 1BGWA 4BLAA 4A3GK 2YU9K 2R92C 3LYWA 1ISEA 1TWHK 1SFOA 3AD9C 4FM9A 1JQWA 3HOWK 1IL2A 2ZJRS 4YFKA 2P5MA 4GTBA 2NVTK 4YG2A 2JA7A 1VJEA 1WQFA 3SZYA 4G0VA 1IS1A 2VUMA 1TWFK 4GTCA 3T02A 3HOVC 1YCLA 5IOSA 3GDZA 1I6HC 2XCRB 5C4JC 2Y3PA 4A3JC 1O2AA 5IYDC 4YFNA 3V4GA 2E2IC 4KAWX 3GTPC 4A3GC 2D6FC 1AB4A 5DM7S 3GSIA 1F9NA 1DCPA 1TWHC 1JOEA 2JA5C 1Y1VK 3BP8C 2XCQA 3GTKA 3FKIC 4X6AK 1TWGK 1USOA 3GTGC 3OREA 5IYCC 4KM9A 3S1NC 3CQZK 2R93K 2NVXK 1TWFC 4FZBA 4AYBL 2Y0SL 3S1RK 2FQOA 4GTFA 4OINA 3HOWC 2WB1L 2JA6C 5C4XK 1WOSA 3RZOK 2W7VA 4G7HA 2E2IK 3VA7A 4A3MC 5IP9C 2JA7K 4IOAS 2JA8C 2PA8L 1DCHA 4BBSC 3QX3A 2PHCB 5C4JK 4Y52C 4BXXC 3ADAC 2GSOA 3GTMA 2NVXA 4GFQA 4KN7A 5M5YK 3TFJA 5IYCK 2E2HC 2R93C 2NVQC 3HOXC 2GAHC 2GSNA 3S1QK 3I4MC 3GTOK 2A6EA 1RU0A 3N0CA 2E2HA 5JVOA 4A3KC 3S2DK 3GTJA 4A93C 4IO9S 1Y1VC 3DXJA 4PABA 3S16K 3K7AK 4C3JC 2PMZD 5IORA 1Y1VA 1ZQ1C 4GTAA 1IBAA 3GTLK 1PJ5A 5D4DA 1XXCA 2ZUEA 3CQZA 1KQ4A 2R93A 4Y7NC 3H3VL 3A8KA 5CJ9A 2NVTC 3BP3A 4C2MC 5TJ3A 1J98A 1XXAA 2ZJPS 2E2HK 1WOOA 4KB2A 3I4MK 3I4NK 1O28A 5FLMC 4M1XA 2NVYC 3H0GA 4XSZA 4KDDA 3GTGA 2Y0SD 1EH1A 3AD8C 3H0GC 4P9SA 4LQYA 3GTQC 4A3JK 4WFBS 3GTMK 4A3EC 4O2DA 2PPBA 2B63A 3GTPK 1O27A 1UV7A 1YX2A 4KC6A 3S14C 4AH6A 3PO2C 5JFEA 4Y7NK 5CHPA 2RH6A 3A8IA 3LAJA 1I50K 3FKIA 3FHZA 1Y1WA 1VRQC 2CW0A 1WCMC 5M5WK 2R7ZC 1B4AA 3N0BA 4KATA 1J6VA 2E2JK 1L0WA 1YNJA 4C3HK 1WSVA 4X6AC 3S2HC 4Q5SA
chains in the Genus database with same CATH topology
1Y1WC 4AYBL 2Y0SL 1SFOK 3S1RK 3HOYK 4OINA 4A3BC 4NOIA 3WODA 3HOWC 2WB1L 2JA6C 4C3HC 5C4XK 4A3KK 4A3LC 2NVXC 4A93K 3K7AC 3RZOK 3HKZD 4QJVB 4C3IC 4KN4A 1IW7A 2R92K 3S1RC 4G7HA 1I3QC 4QIWL 3PO3K 4BY1C 2E2IK 3PO2K 4BXXK 4A3MC 3M4OC 5IP9C 2O5JA 5IYBC 4XLPA 2JA7K 2WAQL 3S1MK 2JA8C 3PO3C 2PA8L 3M3YK 4Q4ZA 4BBSC 1HQMA 5M5XK 4BY1K 5C4JK 4Y52C 4BXXC 5IP9K 4XLNA 4MEXA 3HOUC 4KN7A 5M5YK 1TWAC 3GTOC 3H0GK 4BBRK 3GTKK 4Q5SA 3S14K 2E2JC 4A3DC 5C3EK 5IYCK 3GTMC 2E2HC 4A3FC 2R93C 2NVQC 3I4NC 1K83C 3HOXC 3S1QK 3I4MC 4LK0A 1TWAK 2A6EA 1BDFA 2PA8D 2VUMC 2WB1D 2A69A 1YNNA 2WAQD 1SFOC 3HOYC 4C3JK 2NVYK 4A3KC 5M3MK 2JA6K 3S2DK 4ZH4A 4A93C 4A3BK 1Y1VC 3RZDC 3DXJA 1WCMK 4AYBD 3S1QC 3GTLC 4G7OA 2PMZL 4QIWD 3S16K 3RZOC 3K7AK 1TWCK 4C3JC 5TMCA 5C44K 1I50C 2PMZD 3HKZL 4OIQA 2B63K 3CQZC 3EQLA 3S1NK 2JA5K 4QJVA 3M4OK 4XSXA 5M3FK 3GTLK 1R9TK 3S2HK 5D4DA 2JA8K 2JA7C 3S15C 1TWGC 4G7ZA 3S1MC 5IYBK 3GTOK 3HOZK 2B63C 5IYDK 4KMUA 4YFXA 4A3IK 2R7ZK 4Y7NC 3GTJC 3H3VL 5IP7K 4A3CC 4JK1A 4A3GK 2YU9K 4Y52K 2R92C 3HOUK 1TWHK 2NVTC 3S17C 4C2MC 1Y1WK 3GTKC 2E2HK 4OIOA 4A3DK 2O5IA 3HOWK 2YU9C 4OIPA 3I4MK 4BY7K 2NVQK 4YFKA 3I4NK 2NVTK 3S17K 3FKIK 4YG2A 3GTQK 1SMYA 5FLMC 3S2DC 3HOVK 2NVYC 4A3EK 3S16C 4XSZA 5TMFA 4BY7C 1TWFK 2Y0SD 1TWCC 3H0GC 1ZYRA 3GTQC 3HOVC 4A3JK 1I6HC 5C3EC 5C44C 3GTMK 4A3EC 5C4JC 2PPBA 1K83K 3HOXK 2VUMK 3GTPK 4A3LK 4A3JC 4C3IK 1I6HK 4BBRC 5IYDC 3HOZC 3S14C 4YFNA 3S15K 1I3QK 4LLGA 2E2IC 3PO2C 4LK1A 3GTPC 4Y7NK 3GTJK 5IP7C 4A3GC 4A3MK 4MEYA 4C2MK 4BBSK 1I50K 1TWHC 3H3VD 3M3YC 2JA5C 2CW0A 4MQ9A 1WCMC 1XPPA 1Y1VK 2R7ZC 5M5WK 4OIRA 5FJ8K 3RZDK 3FKIC 4LJZA 4X6AK 1TWGK 3GTGC 4GZYA 5FLMK 5IYCC 4A3IC 2E2JK 3S1NC 3CQZK 4A3CK 2A68A 1YNJA 5C4XC 4C3HK 4X6AC 4A3FK 1R9TC 2NVXK 1TWFC 1I6VA 3S2HC 2R93K 3GTGK 2BE5A 2A6HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1W C;  4AYB L;  2Y0S L;  1SFO K;  3S1R K;  3HOY K;  4OIN A;  4A3B C;  4NOI A;  3WOD A;  3HOW C;  2WB1 L;  2JA6 C;  4C3H C;  5C4X K;  4A3K K;  4A3L C;  2NVX C;  4A93 K;  3K7A C;  3RZO K;  3HKZ D;  4QJV B;  4C3I C;  4KN4 A;  1IW7 A;  2R92 K;  3S1R C;  4G7H A;  1I3Q C;  4QIW L;  3PO3 K;  4BY1 C;  2E2I K;  3PO2 K;  4BXX K;  4A3M C;  3M4O C;  5IP9 C;  2O5J A;  5IYB C;  4XLP A;  2JA7 K;  2WAQ L;  3S1M K;  2JA8 C;  3PO3 C;  2PA8 L;  3M3Y K;  4Q4Z A;  4BBS C;  1HQM A;  5M5X K;  4BY1 K;  5C4J K;  4Y52 C;  4BXX C;  5IP9 K;  4XLN A;  4MEX A;  3HOU C;  4KN7 A;  5M5Y K;  1TWA C;  3GTO C;  3H0G K;  4BBR K;  3GTK K;  4Q5S A;  3S14 K;  2E2J C;  4A3D C;  5C3E K;  5IYC K;  3GTM C;  2E2H C;  4A3F C;  2R93 C;  2NVQ C;  3I4N C;  1K83 C;  3HOX C;  3S1Q K;  3I4M C;  4LK0 A;  1TWA K;  2A6E A;  1BDF A;  2PA8 D;  2VUM C;  2WB1 D;  2A69 A;  1YNN A;  2WAQ D;  1SFO C;  3HOY C;  4C3J K;  2NVY K;  4A3K C;  5M3M K;  2JA6 K;  3S2D K;  4ZH4 A;  4A93 C;  4A3B K;  1Y1V C;  3RZD C;  3DXJ A;  1WCM K;  4AYB D;  3S1Q C;  3GTL C;  4G7O A;  2PMZ L;  4QIW D;  3S16 K;  3RZO C;  3K7A K;  1TWC K;  4C3J C;  5TMC A;  5C44 K;  1I50 C;  2PMZ D;  3HKZ L;  4OIQ A;  2B63 K;  3CQZ C;  3EQL A;  3S1N K;  2JA5 K;  4QJV A;  3M4O K;  4XSX A;  5M3F K;  3GTL K;  1R9T K;  3S2H K;  5D4D A;  2JA8 K;  2JA7 C;  3S15 C;  1TWG C;  4G7Z A;  3S1M C;  5IYB K;  3GTO K;  3HOZ K;  2B63 C;  5IYD K;  4KMU A;  4YFX A;  4A3I K;  2R7Z K;  4Y7N C;  3GTJ C;  3H3V L;  5IP7 K;  4A3C C;  4JK1 A;  4A3G K;  2YU9 K;  4Y52 K;  2R92 C;  3HOU K;  1TWH K;  2NVT C;  3S17 C;  4C2M C;  1Y1W K;  3GTK C;  2E2H K;  4OIO A;  4A3D K;  2O5I A;  3HOW K;  2YU9 C;  4OIP A;  3I4M K;  4BY7 K;  2NVQ K;  4YFK A;  3I4N K;  2NVT K;  3S17 K;  3FKI K;  4YG2 A;  3GTQ K;  1SMY A;  5FLM C;  3S2D C;  3HOV K;  2NVY C;  4A3E K;  3S16 C;  4XSZ A;  5TMF A;  4BY7 C;  1TWF K;  2Y0S D;  1TWC C;  3H0G C;  1ZYR A;  3GTQ C;  3HOV C;  4A3J K;  1I6H C;  5C3E C;  5C44 C;  3GTM K;  4A3E C;  5C4J C;  2PPB A;  1K83 K;  3HOX K;  2VUM K;  3GTP K;  4A3L K;  4A3J C;  4C3I K;  1I6H K;  4BBR C;  5IYD C;  3HOZ C;  3S14 C;  4YFN A;  3S15 K;  1I3Q K;  4LLG A;  2E2I C;  3PO2 C;  4LK1 A;  3GTP C;  4Y7N K;  3GTJ K;  5IP7 C;  4A3G C;  4A3M K;  4MEY A;  4C2M K;  4BBS K;  1I50 K;  1TWH C;  3H3V D;  3M3Y C;  2JA5 C;  2CW0 A;  4MQ9 A;  1WCM C;  1XPP A;  1Y1V K;  2R7Z C;  5M5W K;  4OIR A;  5FJ8 K;  3RZD K;  3FKI C;  4LJZ A;  4X6A K;  1TWG K;  3GTG C;  4GZY A;  5FLM K;  5IYC C;  4A3I C;  2E2J K;  3S1N C;  3CQZ K;  4A3C K;  2A68 A;  1YNJ A;  5C4X C;  4C3H K;  4X6A C;  4A3F K;  1R9T C;  2NVX K;  1TWF C;  1I6V A;  3S2H C;  2R93 K;  3GTG K;  2BE5 A;  2A6H A; 
#chains in the Genus database with same CATH topology
 2KPU A;  3HOY K;  3WOD A;  4XCH A;  4QJV B;  3S1R C;  3PO3 K;  4QIW L;  3GTL A;  3TTG A;  4BY1 C;  1TWH A;  1I3Q A;  4BXX K;  5IYB C;  3S1M K;  3CF5 S;  2XCO A;  4G0W A;  3M3Y K;  1HQM A;  5M5X K;  4BKW A;  5IOQ A;  4PAA A;  4KMD A;  4MEX A;  3HOU C;  4P5B A;  1K83 A;  3SZZ A;  3GTO C;  3GIR A;  1WOR A;  5C3E K;  4A3F C;  4RMF A;  1K83 C;  2PA8 D;  2VUM C;  4C3J K;  3HOY C;  1WQH A;  2L5N A;  5HL7 S;  4WF9 S;  3JST A;  3GTL C;  1BS2 A;  4LOW A;  3T01 A;  3HKZ L;  2B63 K;  4WFA S;  3AD7 C;  1R9T K;  1XZQ B;  3Q3Q A;  3S2H K;  3OPF A;  3S1M C;  3S15 C;  4G7Z A;  5IYB K;  3HOZ K;  3AQP A;  5HL8 A;  1TWG A;  2FQT A;  2ZFZ A;  5IP7 K;  3HOU K;  2E2I A;  3S17 C;  1Y1W K;  5E68 A;  4OIO A;  4A3D K;  2O5I A;  1VGX A;  4BY7 K;  3A8J A;  3FKI K;  1I50 A;  3TFI A;  3GTQ K;  3IPJ A;  4LR2 A;  4C45 A;  4A3E K;  3FOE A;  5TMF A;  3CAG A;  1TWC C;  5C3E C;  5C44 C;  2P8T A;  1F93 A;  1K83 K;  1BJT A;  4DDQ A;  1USM A;  3HOZ C;  1TWA A;  3S15 K;  1I3Q K;  3GEE A;  1HI9 A;  1JVI A;  4KMA A;  5IP7 C;  4A3M K;  2JA5 A;  4BBS K;  3H3V D;  1VH2 A;  1EK8 A;  4MQ9 A;  3RZD K;  1XPP A;  1WSR A;  3DLL S;  4GZY A;  1ZBS A;  5JVG S;  1F7U A;  4A3I C;  4J3N A;  2R7Z K;  1I6V A;  4KM8 A;  1Y1W C;  5DM6 S;  4A3K K;  4C3H C;  1J6W A;  4IOC S;  4WCE S;  4A93 K;  3K7A C;  3HKZ D;  5IOT A;  3AH5 A;  4KN4 A;  1WIH A;  1G51 A;  1I3Q C;  2JA6 A;  1V5V A;  2GAG C;  1O26 A;  4KAS A;  3M4O C;  2O5J A;  3GTQ A;  1TWF A;  3HXA A;  3PO3 C;  2JH3 A;  2V6T A;  1EFW A;  4BY1 K;  3FOF A;  3NUH A;  4KAR A;  1TWA C;  3H0G K;  4G0U A;  1WOP A;  3GTK K;  1GE9 A;  3GTM C;  1F7V A;  3I4N C;  3G4C A;  4P5A A;  4A3L C;  2WB1 D;  2WAQ D;  4GTE A;  5EGH A;  2NVY K;  2JA6 K;  1IE0 A;  1X31 C;  4ZH4 A;  2ZUF A;  3RZD C;  4AYB D;  4G7O A;  4QIW D;  3RZO C;  1I50 C;  4OIQ A;  3CQZ C;  3S1N K;  1XZQ A;  4QJV A;  3M4O K;  1EQR A;  1ZVU A;  2JA8 K;  1DD5 A;  2JA7 C;  4WJ3 M;  2B63 C;  2CFA B;  4KMU A;  1DCO A;  3GTJ C;  1XZP B;  4Y52 K;  2KWA A;  4A3C C;  4JK1 A;  4GTD A;  5L46 A;  3GTK C;  4WJ4 A;  2YU9 C;  4OIP A;  2NVQ K;  3S17 K;  3BUE A;  3HOV K;  1SMY A;  3S2D C;  4KMH A;  3S16 C;  4BY7 C;  1ZYR A;  1EI6 A;  3S0X A;  1TWC A;  2R7Z A;  3HOX K;  2YU9 A;  4A3L K;  3PIO S;  4C3I K;  1J6X A;  1I6H K;  4BBR C;  3GTO A;  1PJ6 A;  4LLG A;  3T00 A;  4LK1 A;  1XXB A;  3L4K A;  3GTJ K;  1B4B A;  3L4J A;  4MEY A;  2EBB A;  4WIL A;  4C2M K;  2GSU A;  3M3Y C;  3PIP S;  1O24 A;  5FJ8 K;  4OIR A;  3ERE D;  4LJZ A;  3AQO A;  2L3U A;  5FLM K;  4ILD A;  4A3C K;  2A68 A;  5C4X C;  1IQ0 A;  4A3F K;  4WFN S;  2KQ1 A;  1R9T C;  1XZP A;  2VUM K;  3GTG K;  2NVY A;  2BE5 A;  2A6H A;  3G4A A;  1SFO K;  3LAP A;  4A3B C;  2KXY A;  4NOI A;  2NVX C;  4BLB A;  4C3I C;  3GTP A;  4KB4 A;  1IW7 A;  1O2B A;  2R92 K;  2V6U A;  1R9T A;  1WCM A;  3LPX A;  3PO2 K;  4GTL A;  3MML B;  3OEP A;  4XLP A;  2RGR A;  2WAQ L;  4Q4Z A;  1O25 A;  1INN A;  4U67 S;  5HQH A;  5IP9 K;  4XLN A;  3GEI A;  4GT9 A;  3TFH A;  4BBR K;  3S14 K;  2E2J C;  4A3D C;  3GEH A;  1O2F B;  1TWA K;  4LK0 A;  5JVH S;  1BDF A;  1SFO C;  2A69 A;  1YNN A;  2R92 A;  1PJ7 A;  1ZXO A;  5M3M K;  4A3B K;  1WCM K;  3S1Q C;  2PMZ L;  1FEU A;  5EGE A;  1TWC K;  5TMC A;  2CFA A;  1VLO A;  5C44 K;  1C0A A;  3EQL A;  2JA5 K;  1O29 A;  2ZJQ S;  4XSX A;  2V6S A;  5M3F K;  1WQG A;  3N3Y A;  5IYD K;  1TWG C;  4YFX A;  4A3I K;  1BGW A;  4BLA A;  4A3G K;  2YU9 K;  2R92 C;  3LYW A;  1ISE A;  1TWH K;  1SFO A;  3AD9 C;  4FM9 A;  1JQW A;  3HOW K;  1IL2 A;  2ZJR S;  4YFK A;  2P5M A;  4GTB A;  2NVT K;  4YG2 A;  2JA7 A;  1VJE A;  1WQF A;  3SZY A;  4G0V A;  1IS1 A;  2VUM A;  1TWF K;  4GTC A;  3T02 A;  3HOV C;  1YCL A;  5IOS A;  3GDZ A;  1I6H C;  2XCR B;  5C4J C;  2Y3P A;  4A3J C;  1O2A A;  5IYD C;  4YFN A;  3V4G A;  2E2I C;  4KAW X;  3GTP C;  4A3G C;  2D6F C;  1AB4 A;  5DM7 S;  3GSI A;  1F9N A;  1DCP A;  1TWH C;  1JOE A;  2JA5 C;  1Y1V K;  3BP8 C;  2XCQ A;  3GTK A;  3FKI C;  4X6A K;  1TWG K;  1USO A;  3GTG C;  3ORE A;  5IYC C;  4KM9 A;  3S1N C;  3CQZ K;  2R93 K;  2NVX K;  1TWF C;  4FZB A;  4AYB L;  2Y0S L;  3S1R K;  2FQO A;  4GTF A;  4OIN A;  3HOW C;  2WB1 L;  2JA6 C;  5C4X K;  1WOS A;  3RZO K;  2W7V A;  4G7H A;  2E2I K;  3VA7 A;  4A3M C;  5IP9 C;  2JA7 K;  4IOA S;  2JA8 C;  2PA8 L;  1DCH A;  4BBS C;  3QX3 A;  2PHC B;  5C4J K;  4Y52 C;  4BXX C;  3ADA C;  2GSO A;  3GTM A;  2NVX A;  4GFQ A;  4KN7 A;  5M5Y K;  3TFJ A;  5IYC K;  2E2H C;  2R93 C;  2NVQ C;  3HOX C;  2GAH C;  2GSN A;  3S1Q K;  3I4M C;  3GTO K;  2A6E A;  1RU0 A;  3N0C A;  2E2H A;  5JVO A;  4A3K C;  3S2D K;  3GTJ A;  4A93 C;  4IO9 S;  1Y1V C;  3DXJ A;  4PAB A;  3S16 K;  3K7A K;  4C3J C;  2PMZ D;  5IOR A;  1Y1V A;  1ZQ1 C;  4GTA A;  1IBA A;  3GTL K;  1PJ5 A;  5D4D A;  1XXC A;  2ZUE A;  3CQZ A;  1KQ4 A;  2R93 A;  4Y7N C;  3H3V L;  3A8K A;  5CJ9 A;  2NVT C;  3BP3 A;  4C2M C;  5TJ3 A;  1J98 A;  1XXA A;  2ZJP S;  2E2H K;  1WOO A;  4KB2 A;  3I4M K;  3I4N K;  1O28 A;  5FLM C;  4M1X A;  2NVY C;  3H0G A;  4XSZ A;  4KDD A;  3GTG A;  2Y0S D;  1EH1 A;  3AD8 C;  3H0G C;  4P9S A;  4LQY A;  3GTQ C;  4A3J K;  4WFB S;  3GTM K;  4A3E C;  4O2D A;  2PPB A;  2B63 A;  3GTP K;  1O27 A;  1UV7 A;  1YX2 A;  4KC6 A;  3S14 C;  4AH6 A;  3PO2 C;  5JFE A;  4Y7N K;  5CHP A;  2RH6 A;  3A8I A;  3LAJ A;  1I50 K;  3FKI A;  3FHZ A;  1Y1W A;  1VRQ C;  2CW0 A;  1WCM C;  5M5W K;  2R7Z C;  1B4A A;  3N0B A;  4KAT A;  1J6V A;  2E2J K;  1L0W A;  1YNJ A;  4C3H K;  1WSV A;  4X6A C;  3S2H C;  4Q5S A; 
#chains in the Genus database with same CATH homology
 1Y1W C;  4AYB L;  2Y0S L;  1SFO K;  3S1R K;  3HOY K;  4OIN A;  4A3B C;  4NOI A;  3WOD A;  3HOW C;  2WB1 L;  2JA6 C;  4C3H C;  5C4X K;  4A3K K;  4A3L C;  2NVX C;  4A93 K;  3K7A C;  3RZO K;  3HKZ D;  4QJV B;  4C3I C;  4KN4 A;  1IW7 A;  2R92 K;  3S1R C;  4G7H A;  1I3Q C;  4QIW L;  3PO3 K;  4BY1 C;  2E2I K;  3PO2 K;  4BXX K;  4A3M C;  3M4O C;  5IP9 C;  2O5J A;  5IYB C;  4XLP A;  2JA7 K;  2WAQ L;  3S1M K;  2JA8 C;  3PO3 C;  2PA8 L;  3M3Y K;  4Q4Z A;  4BBS C;  1HQM A;  5M5X K;  4BY1 K;  5C4J K;  4Y52 C;  4BXX C;  5IP9 K;  4XLN A;  4MEX A;  3HOU C;  4KN7 A;  5M5Y K;  1TWA C;  3GTO C;  3H0G K;  4BBR K;  3GTK K;  4Q5S A;  3S14 K;  2E2J C;  4A3D C;  5C3E K;  5IYC K;  3GTM C;  2E2H C;  4A3F C;  2R93 C;  2NVQ C;  3I4N C;  1K83 C;  3HOX C;  3S1Q K;  3I4M C;  4LK0 A;  1TWA K;  2A6E A;  1BDF A;  2PA8 D;  2VUM C;  2WB1 D;  2A69 A;  1YNN A;  2WAQ D;  1SFO C;  3HOY C;  4C3J K;  2NVY K;  4A3K C;  5M3M K;  2JA6 K;  3S2D K;  4ZH4 A;  4A93 C;  4A3B K;  1Y1V C;  3RZD C;  3DXJ A;  1WCM K;  4AYB D;  3S1Q C;  3GTL C;  4G7O A;  2PMZ L;  4QIW D;  3S16 K;  3RZO C;  3K7A K;  1TWC K;  4C3J C;  5TMC A;  5C44 K;  1I50 C;  2PMZ D;  3HKZ L;  4OIQ A;  2B63 K;  3CQZ C;  3EQL A;  3S1N K;  2JA5 K;  4QJV A;  3M4O K;  4XSX A;  5M3F K;  3GTL K;  1R9T K;  3S2H K;  5D4D A;  2JA8 K;  2JA7 C;  3S15 C;  1TWG C;  4G7Z A;  3S1M C;  5IYB K;  3GTO K;  3HOZ K;  2B63 C;  5IYD K;  4KMU A;  4YFX A;  4A3I K;  2R7Z K;  4Y7N C;  3GTJ C;  3H3V L;  5IP7 K;  4A3C C;  4JK1 A;  4A3G K;  2YU9 K;  4Y52 K;  2R92 C;  3HOU K;  1TWH K;  2NVT C;  3S17 C;  4C2M C;  1Y1W K;  3GTK C;  2E2H K;  4OIO A;  4A3D K;  2O5I A;  3HOW K;  2YU9 C;  4OIP A;  3I4M K;  4BY7 K;  2NVQ K;  4YFK A;  3I4N K;  2NVT K;  3S17 K;  3FKI K;  4YG2 A;  3GTQ K;  1SMY A;  5FLM C;  3S2D C;  3HOV K;  2NVY C;  4A3E K;  3S16 C;  4XSZ A;  5TMF A;  4BY7 C;  1TWF K;  2Y0S D;  1TWC C;  3H0G C;  1ZYR A;  3GTQ C;  3HOV C;  4A3J K;  1I6H C;  5C3E C;  5C44 C;  3GTM K;  4A3E C;  5C4J C;  2PPB A;  1K83 K;  3HOX K;  2VUM K;  3GTP K;  4A3L K;  4A3J C;  4C3I K;  1I6H K;  4BBR C;  5IYD C;  3HOZ C;  3S14 C;  4YFN A;  3S15 K;  1I3Q K;  4LLG A;  2E2I C;  3PO2 C;  4LK1 A;  3GTP C;  4Y7N K;  3GTJ K;  5IP7 C;  4A3G C;  4A3M K;  4MEY A;  4C2M K;  4BBS K;  1I50 K;  1TWH C;  3H3V D;  3M3Y C;  2JA5 C;  2CW0 A;  4MQ9 A;  1WCM C;  1XPP A;  1Y1V K;  2R7Z C;  5M5W K;  4OIR A;  5FJ8 K;  3RZD K;  3FKI C;  4LJZ A;  4X6A K;  1TWG K;  3GTG C;  4GZY A;  5FLM K;  5IYC C;  4A3I C;  2E2J K;  3S1N C;  3CQZ K;  4A3C K;  2A68 A;  1YNJ A;  5C4X C;  4C3H K;  4X6A C;  4A3F K;  1R9T C;  2NVX K;  1TWF C;  1I6V A;  3S2H C;  2R93 K;  3GTG K;  2BE5 A;  2A6H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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