4LK1A

Crystal structure analysis of the e.coli holoenzyme
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 40
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-07-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4lk1A02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4lk1A01
3GTLC 3HOZC 2B63K 5IP9C 3I4NC 2NVQK 3GTGK 4A3MK 3HOVK 4XLNA 4G7OA 5C44C 4OIQA 3S1NC 1TWCC 5TMFA 4A3FC 2O5JA 2NVYK 3FKIK 5M5YK 4G7ZA 1YNJA 2PA8L 3H0GC 4QIWL 3M4OK 5C4JK 2Y0SL 3GTJC 1ZYRA 1Y1WC 3I4MC 2R92K 3GTOC 3HOYC 2R93K 4BXXC 3S15K 3GTQK 5C3EK 5C4XC 2WB1L 4OIRA 3S2DK 4KN4A 2A6HA 4KN7A 4QIWD 2VUMC 1R9TK 5IYDK 4A3KC 1TWGC 4C3JC 3GTKC 3HOWC 4LK0A 3PO2C 1Y1VK 5M3FK 4A93K 3DXJA 3HOUC 3HOXK 5FJ8K 4Q5SA 3PO2K 4C3HC 1I3QC 3GTPC 2NVTK 3CQZK 4C2MC 4MQ9A 4A3LC 1TWGK 3HOWK 2JA8C 4C3IK 2E2HK 2R7ZK 1TWFK 3GTQC 1TWAC 2BE5A 5FLMK 2PMZL 1IW7A 4BXXK 5M3MK 4X6AK 1TWAK 3HOYK 2WAQD 3M3YK 4X6AC 2R7ZC 2CW0A 2WB1D 4YFNA 4YFKA 5C4JC 3H0GK 4ZH4A 3S1MK 1TWFC 5M5XK 1K83C 2NVTC 3S16C 2PPBA 3RZOC 4A3FK 3GTPK 1I50C 4C3IC 2JA8K 4C3HK 4A3LK 4YG2A 1YNNA 3HOUK 4XLPA 3CQZC 1Y1VC 5D4DA 4C2MK 4A3CK 1I3QK 4NOIA 4LK1A 4OINA 1I50K 5M5WK 4LLGA 2JA6K 3RZOK 1R9TC 1K83K 3PO3K 5C4XK 4LJZA 4Q4ZA 4XSXA 5C3EC 3S1MC 4A93C 2NVXC 4C3JK 4KMUA 4A3KK 3GTKK 2JA5K 3S2DC 2JA7C 4AYBL 3M3YC 2R93C 2E2JC 3EQLA 4JK1A 2R92C 3I4MK 1Y1WK 3GTMK 5FLMC 4AYBD 4MEYA 3S17K 4A3JK 3HKZL 1HQMA 1I6VA 2E2HC 2A69A 3GTJK 4A3GK 3FKIC 2NVYC 2B63C 3M4OC 1TWCK 3WODA 1TWHC 4BBRK 5C44K 3GTLK 3HOZK 3HOXC 3K7AC 2NVQC 3GTGC 5IP9K 4A3BK 2WAQL 2YU9K 5IYBC 1BDFA 2VUMK 5IYDC 1WCMC 2PMZD 1XPPA 3S15C 4A3DC 3HKZD 3RZDC 3S1QK 2PA8D 3PO3C 4A3EK 4OIOA 3GTOK 5IYBK 4XSZA 4MEXA 5IYCC 3S1RC 4Y52K 4A3IK 3S16K 3H3VL 4OIPA 4BY1C 4BBSC 2E2IK 1SFOC 3S1NK 4BBRC 2O5IA 1TWHK 5IP7K 3S14K 2E2IC 4BBSK 3HOVC 2A68A 4A3MC 4A3GC 4A3IC 3I4NK 5IP7C 3S14C 1SFOK 5TMCA 2A6EA 4A3CC 4A3JC 3S17C 4QJVB 4Y52C 4BY1K 3S2HK 5IYCK 3S1RK 4QJVA 4Y7NC 3GTMC 4BY7C 1I6HK 4G7HA 3RZDK 4A3DK 2E2JK 1SMYA 4A3EC 2JA7K 2Y0SD 2JA5C 3H3VD 3S1QC 2YU9C 2NVXK 4GZYA 1I6HC 4Y7NK 4BY7K 4A3BC 1WCMK 4YFXA 3K7AK 3S2HC 2JA6C
chains in the Genus database with same CATH superfamily
3GTLC 4WJ3M 3GTGK 4GTLA 1O26A 4WFNS 3HOVK 1O25A 1B4BA 4OIQA 3S1NC 2O5JA 4A3FC 5M5YK 2NVYK 4WF9S 3S16K 3H0GC 4P5AA 1BGWA 3JSTA 4KMDA 1USOA 4PAAA 5DM7S 5C3EK 4J3NA 5C4XC 4QIWD 1WSVA 1TWGC 2KWAA 1G51A 3HOUC 1I3QA 5FJ8K 5DM6S 4C2MC 3HOWK 5E68A 4ILDA 1VJEA 3GTQC 4O2DA 2BE5A 1J6WA 4X6AK 2Y3PA 2KPUA 4M1XA 1GE9A 3S1MK 5M5XK 2GAGC 3GTPA 3GTPK 3TFIA 5JVHS 1HI9A 2JA8K 1O2AA 4XLPA 4C2MK 3LAPA 1I3QK 3FKIA 4NOIA 1I50K 2VUMA 5C4XK 4XSXA 4A93C 5C3EC 2JA5K 4IO9S 2JA7C 1PJ6A 4JK1A 4KMAA 3OPFA 2FQOA 1TWAA 1HQMA 2E2HC 1XZPA 3CF5S 2NVYC 3A8JA 1L0WA 3HOXC 3K7AC 3GTGC 4KARA 2E2HA 2ZJRS 2ZFZA 2YU9A 1BDFA 3T00A 1WOOA 2VUMK 1IE0A 2P8TA 4GTDA 1R9TA 3S1RC 1V5VA 4Y52K 3LPXA 1TWHK 5JFEA 2E2IC 4BBSK 2A68A 4A3GC 3I4NK 2V6UA 3AQOA 4G0UA 1WOSA 3S2HK 3GTKA 5IYCK 2ZUFA 4KM8A 4WCES 2YU9C 2NVXK 4GZYA 1I6HC 4Y7NK 1J6XA 3TFJA 4YFXA 3K7AK 1WCMA 3S2HC 1IBAA 2B63K 5IP9C 3A8IA 2NVQK 4XLNA 1ZVUA 5C44C 2E2IA 1O29A 1TWCC 1TWHA 2P5MA 3M4OK 4G7ZA 2Y0SL 3GTJC 3BUEA 1ZYRA 4WILA 1O2FB 3HOYC 3A8KA 2CFAA 1ZQ1C 2WB1L 1XXBA 5IOTA 3S2DK 5IYDK 2VUMC 3V4GA 4C3JC 2ZJQS 5IORA 3HOXK 4Q5SA 3GTPC 3GSIA 1SFOA 2XCOA 4A3LC 4KAWX 5EGEA 1J98A 4C3IK 2E2HK 1TWFK 1F7VA 1TWAC 2JH3A 2PMZL 1IW7A 3N0CA 1BJTA 1O2BA 3AQPA 4BKWA 2WB1D 4YFNA 1EQRA 4YFKA 4ZH4A 4IOAS 2PPBA 1YCLA 1EI6A 4C3HK 4KMHA 4G0WA 3HOUK 1ISEA 4WJ4A 4FZBA 3AD8C 1R9TC 4LJZA 3S1MC 3PO2K 2NVXC 4A3KK 2JA5A 2R93C 1IQ0A 1WQFA 3QX3A 1Y1WK 1EH1A 4KB2A 4MEYA 2GSNA 1I6VA 4A3GK 3CQZA 1DCHA 4BBRK 2B63A 3DLLS 1DCOA 3GTLK 4A3BK 1TWFA 1F9NA 5IYDC 5JVOA 3S0XA 4A3DC 3HKZD 1UV7A 2GSOA 3RZDC 4GTBA 4PABA 3OREA 1B4AA 4C45A 3LAJA 1IL2A 2EBBA 1SFOC 4BBRC 3S14K 1WSRA 4A3IC 3S14C 2JA6C 2CFAB 2XCQA 1SFOK 5TMCA 4QJVB 1I6HK 4Y7NC 1FEUA 2R7ZA 3GDZA 1SMYA 2Y0SD 2JA5C 3H3VD 3S1QC 2NVXA 4LOWA 1WCMK 3HOZC 1C0AA 3GEEA 3I4NC 4A3MK 4G7OA 1JOEA 4GFQA 5EGHA 3FKIK 3I4MC 4P9SA 2L5NA 4OIRA 4KN4A 2A6HA 4KN7A 4A3KC 3HOWC 3GTKC 3PO2C 2L3UA 1WIHA 2NVTK 3CQZK 3GTLA 4MQ9A 1DD5A 1TWGK 1VRQC 2RH6A 4KASA 2R7ZK 1XXAA 3FHZA 1XXCA 4KB4A 2ZJPS 5FLMK 5M3MK 1EK8A 2WAQD 3HOYK 3M3YK 5HL8A 3GTJA 3G4AA 1TWFC 3SZZA 5CJ9A 2NVTC 3S16C 4A3FK 3AD7C 1I50C 4C3IC 1O27A 4YG2A 1YNNA 3CQZC 1Y1VC 5D4DA 4LK1A 4LLGA 3RZOK 3TFHA 1K83A 4Q4ZA 3GTKK 3EQLA 1DCPA 2R92C 4LR2A 3GTMK 3GEIA 4GT9A 3SZYA 4WFBS 2RGRA 3GTJK 3FKIC 1VGXA 1TWCK 1TWHC 1TWCA 5C44K 5L46A 3NUHA 1JVIA 2WAQL 1WCMC 1XPPA 3S1QK 2PA8D 2KXYA 1PJ5A 1IS1A 4OIOA 3MMLB 3GTOK 1USMA 4XSZA 5IYCC 1PJ7A 5IOQA 5JVGS 3S1NK 1ZBSA 3HOVC 4AH6A 1I50A 1J6VA 1RU0A 3GEHA 3N0BA 4A3CC 4A3JC 3IPJA 4BY1K 1VH2A 3S1RK 4BY7C 4G7HA 4A3DK 2JA7A 2JA7K 3L4JA 2D6FC 4A3CK 4WFAS 4U67S 4DDQA 2GSUA 1F93A 5TMFA 3OEPA 5TJ3A 3AH5A 2NVYA 2PA8L 1YNJA 4QIWL 5C4JK 4KDDA 4GTEA 1Y1WC 4KATA 2R92A 2R92K 3GTOC 2R93K 4KC6A 3BP8C 4BXXC 4XCHA 3GTOA 3S15K 1Y1WA 3GTQK 3HXAA 3GTMA 1R9TK 4KM9A 4GTCA 4GTAA 5HQHA 1WQGA 3G4CA 1Y1VA 4LK0A 4A93K 1Y1VK 5M3FK 4IOCS 3DXJA 4C3HC 3VA7A 1I3QC 1INNA 1KQ4A 4FM9A 2JA8C 3GIRA 4BXXK 1TWAK 3FOFA 4X6AC 2R7ZC 1WQHA 4GTFA 1XZPB 2CW0A 4P5BA 3PIOS 5C4JC 3FOEA 3H0GK 1K83C 2GAHC 1YX2A 3ERED 3RZOC 3GTGA 4A3LK 4OINA 5M5WK 2JA6A 2JA6K 3PO3K 1K83K 1BS2A 4C3JK 4KMUA 1TWGA 2W7VA 1VLOA 1WOPA 1WORA 3S2DC 4AYBL 3M3YC 2E2JC 4RMFA 1EFWA 5HL7S 3TTGA 3I4MK 4G0VA 5FLMC 4AYBD 4BLAA 3S17K 2KQ1A 1XZQB 3HKZL 4A3JK 2ZUEA 3Q3QA 2A69A 1F7UA 1X31C 3CAGA 3M4OC 2B63C 3WODA 3BP3A 2V6TA 5CHPA 3HOZK 3L4KA 2NVQC 5IP9K 2FQTA 4BLBA 2YU9K 5IYBC 2V6SA 2PMZD 3S15C 2PHCB 2R93A 4A3EK 2XCRB 5IYBK 3GTQA 3AD9C 4MEXA 4A3IK 4LQYA 3H3VL 4OIPA 4BBSC 2E2IK 1AB4A 2O5IA 1O24A 5IP7K 4A3MC 5IP7C 3PIPS 3N3YA 2A6EA 3T01A 5IOSA 3S17C 1O28A 3LYWA 4Y52C 4QJVA 3GTMC 3RZDK 1ZXOA 2E2JK 4A3EC 1JQWA 3ADAC 3T02A 1XZQA 4BY7K 4A3BC 4BY1C 3H0GA 3PO3C
chains in the Genus database with same CATH topology
3GTLC 3HOZC 2B63K 5IP9C 3I4NC 2NVQK 3GTGK 4A3MK 3HOVK 4XLNA 4G7OA 5C44C 4OIQA 3S1NC 1TWCC 5TMFA 4A3FC 2O5JA 2NVYK 3FKIK 5M5YK 4G7ZA 1YNJA 2PA8L 3H0GC 4QIWL 3M4OK 5C4JK 2Y0SL 3GTJC 1ZYRA 1Y1WC 3I4MC 2R92K 3GTOC 3HOYC 2R93K 4BXXC 3S15K 3GTQK 5C3EK 5C4XC 2WB1L 4OIRA 3S2DK 4KN4A 2A6HA 4KN7A 4QIWD 2VUMC 1R9TK 5IYDK 4A3KC 1TWGC 4C3JC 3GTKC 3HOWC 4LK0A 3PO2C 1Y1VK 5M3FK 4A93K 3DXJA 3HOUC 3HOXK 5FJ8K 4Q5SA 3PO2K 4C3HC 1I3QC 3GTPC 2NVTK 3CQZK 4C2MC 4MQ9A 4A3LC 1TWGK 3HOWK 2JA8C 4C3IK 2E2HK 2R7ZK 1TWFK 3GTQC 1TWAC 2BE5A 5FLMK 2PMZL 1IW7A 4BXXK 5M3MK 4X6AK 1TWAK 3HOYK 2WAQD 3M3YK 4X6AC 2R7ZC 2CW0A 2WB1D 4YFNA 4YFKA 5C4JC 3H0GK 4ZH4A 3S1MK 1TWFC 5M5XK 1K83C 2NVTC 3S16C 2PPBA 3RZOC 4A3FK 3GTPK 1I50C 4C3IC 2JA8K 4C3HK 4A3LK 4YG2A 1YNNA 3HOUK 4XLPA 3CQZC 1Y1VC 5D4DA 4C2MK 4A3CK 1I3QK 4NOIA 4LK1A 4OINA 1I50K 5M5WK 4LLGA 2JA6K 3RZOK 1R9TC 1K83K 3PO3K 5C4XK 4LJZA 4Q4ZA 4XSXA 5C3EC 3S1MC 4A93C 2NVXC 4C3JK 4KMUA 4A3KK 3GTKK 2JA5K 3S2DC 2JA7C 4AYBL 3M3YC 2R93C 2E2JC 3EQLA 4JK1A 2R92C 3I4MK 1Y1WK 3GTMK 5FLMC 4AYBD 4MEYA 3S17K 4A3JK 3HKZL 1HQMA 1I6VA 2E2HC 2A69A 3GTJK 4A3GK 3FKIC 2NVYC 2B63C 3M4OC 1TWCK 3WODA 1TWHC 4BBRK 5C44K 3GTLK 3HOZK 3HOXC 3K7AC 2NVQC 3GTGC 5IP9K 4A3BK 2WAQL 2YU9K 5IYBC 1BDFA 2VUMK 5IYDC 1WCMC 2PMZD 1XPPA 3S15C 4A3DC 3HKZD 3RZDC 3S1QK 2PA8D 3PO3C 4A3EK 4OIOA 3GTOK 5IYBK 4XSZA 4MEXA 5IYCC 3S1RC 4Y52K 4A3IK 3S16K 3H3VL 4OIPA 4BY1C 4BBSC 2E2IK 1SFOC 3S1NK 4BBRC 2O5IA 1TWHK 5IP7K 3S14K 2E2IC 4BBSK 3HOVC 2A68A 4A3MC 4A3GC 4A3IC 3I4NK 5IP7C 3S14C 1SFOK 5TMCA 2A6EA 4A3CC 4A3JC 3S17C 4QJVB 4Y52C 4BY1K 3S2HK 5IYCK 3S1RK 4QJVA 4Y7NC 3GTMC 4BY7C 1I6HK 4G7HA 3RZDK 4A3DK 2E2JK 1SMYA 4A3EC 2JA7K 2Y0SD 2JA5C 3H3VD 3S1QC 2YU9C 2NVXK 4GZYA 1I6HC 4Y7NK 4BY7K 4A3BC 1WCMK 4YFXA 3K7AK 3S2HC 2JA6C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTL C;  3HOZ C;  2B63 K;  5IP9 C;  3I4N C;  2NVQ K;  3GTG K;  4A3M K;  3HOV K;  4XLN A;  4G7O A;  5C44 C;  4OIQ A;  3S1N C;  1TWC C;  5TMF A;  4A3F C;  2O5J A;  2NVY K;  3FKI K;  5M5Y K;  4G7Z A;  1YNJ A;  2PA8 L;  3H0G C;  4QIW L;  3M4O K;  5C4J K;  2Y0S L;  3GTJ C;  1ZYR A;  1Y1W C;  3I4M C;  2R92 K;  3GTO C;  3HOY C;  2R93 K;  4BXX C;  3S15 K;  3GTQ K;  5C3E K;  5C4X C;  2WB1 L;  4OIR A;  3S2D K;  4KN4 A;  2A6H A;  4KN7 A;  4QIW D;  2VUM C;  1R9T K;  5IYD K;  4A3K C;  1TWG C;  4C3J C;  3GTK C;  3HOW C;  4LK0 A;  3PO2 C;  1Y1V K;  5M3F K;  4A93 K;  3DXJ A;  3HOU C;  3HOX K;  5FJ8 K;  4Q5S A;  3PO2 K;  4C3H C;  1I3Q C;  3GTP C;  2NVT K;  3CQZ K;  4C2M C;  4MQ9 A;  4A3L C;  1TWG K;  3HOW K;  2JA8 C;  4C3I K;  2E2H K;  2R7Z K;  1TWF K;  3GTQ C;  1TWA C;  2BE5 A;  5FLM K;  2PMZ L;  1IW7 A;  4BXX K;  5M3M K;  4X6A K;  1TWA K;  3HOY K;  2WAQ D;  3M3Y K;  4X6A C;  2R7Z C;  2CW0 A;  2WB1 D;  4YFN A;  4YFK A;  5C4J C;  3H0G K;  4ZH4 A;  3S1M K;  1TWF C;  5M5X K;  1K83 C;  2NVT C;  3S16 C;  2PPB A;  3RZO C;  4A3F K;  3GTP K;  1I50 C;  4C3I C;  2JA8 K;  4C3H K;  4A3L K;  4YG2 A;  1YNN A;  3HOU K;  4XLP A;  3CQZ C;  1Y1V C;  5D4D A;  4C2M K;  4A3C K;  1I3Q K;  4NOI A;  4LK1 A;  4OIN A;  1I50 K;  5M5W K;  4LLG A;  2JA6 K;  3RZO K;  1R9T C;  1K83 K;  3PO3 K;  5C4X K;  4LJZ A;  4Q4Z A;  4XSX A;  5C3E C;  3S1M C;  4A93 C;  2NVX C;  4C3J K;  4KMU A;  4A3K K;  3GTK K;  2JA5 K;  3S2D C;  2JA7 C;  4AYB L;  3M3Y C;  2R93 C;  2E2J C;  3EQL A;  4JK1 A;  2R92 C;  3I4M K;  1Y1W K;  3GTM K;  5FLM C;  4AYB D;  4MEY A;  3S17 K;  4A3J K;  3HKZ L;  1HQM A;  1I6V A;  2E2H C;  2A69 A;  3GTJ K;  4A3G K;  3FKI C;  2NVY C;  2B63 C;  3M4O C;  1TWC K;  3WOD A;  1TWH C;  4BBR K;  5C44 K;  3GTL K;  3HOZ K;  3HOX C;  3K7A C;  2NVQ C;  3GTG C;  5IP9 K;  4A3B K;  2WAQ L;  2YU9 K;  5IYB C;  1BDF A;  2VUM K;  5IYD C;  1WCM C;  2PMZ D;  1XPP A;  3S15 C;  4A3D C;  3HKZ D;  3RZD C;  3S1Q K;  2PA8 D;  3PO3 C;  4A3E K;  4OIO A;  3GTO K;  5IYB K;  4XSZ A;  4MEX A;  5IYC C;  3S1R C;  4Y52 K;  4A3I K;  3S16 K;  3H3V L;  4OIP A;  4BY1 C;  4BBS C;  2E2I K;  1SFO C;  3S1N K;  4BBR C;  2O5I A;  1TWH K;  5IP7 K;  3S14 K;  2E2I C;  4BBS K;  3HOV C;  2A68 A;  4A3M C;  4A3G C;  4A3I C;  3I4N K;  5IP7 C;  3S14 C;  1SFO K;  5TMC A;  2A6E A;  4A3C C;  4A3J C;  3S17 C;  4QJV B;  4Y52 C;  4BY1 K;  3S2H K;  5IYC K;  3S1R K;  4QJV A;  4Y7N C;  3GTM C;  4BY7 C;  1I6H K;  4G7H A;  3RZD K;  4A3D K;  2E2J K;  1SMY A;  4A3E C;  2JA7 K;  2Y0S D;  2JA5 C;  3H3V D;  3S1Q C;  2YU9 C;  2NVX K;  4GZY A;  1I6H C;  4Y7N K;  4BY7 K;  4A3B C;  1WCM K;  4YFX A;  3K7A K;  3S2H C;  2JA6 C; 
#chains in the Genus database with same CATH topology
 3GTL C;  4WJ3 M;  3GTG K;  4GTL A;  1O26 A;  4WFN S;  3HOV K;  1O25 A;  1B4B A;  4OIQ A;  3S1N C;  2O5J A;  4A3F C;  5M5Y K;  2NVY K;  4WF9 S;  3S16 K;  3H0G C;  4P5A A;  1BGW A;  3JST A;  4KMD A;  1USO A;  4PAA A;  5DM7 S;  5C3E K;  4J3N A;  5C4X C;  4QIW D;  1WSV A;  1TWG C;  2KWA A;  1G51 A;  3HOU C;  1I3Q A;  5FJ8 K;  5DM6 S;  4C2M C;  3HOW K;  5E68 A;  4ILD A;  1VJE A;  3GTQ C;  4O2D A;  2BE5 A;  1J6W A;  4X6A K;  2Y3P A;  2KPU A;  4M1X A;  1GE9 A;  3S1M K;  5M5X K;  2GAG C;  3GTP A;  3GTP K;  3TFI A;  5JVH S;  1HI9 A;  2JA8 K;  1O2A A;  4XLP A;  4C2M K;  3LAP A;  1I3Q K;  3FKI A;  4NOI A;  1I50 K;  2VUM A;  5C4X K;  4XSX A;  4A93 C;  5C3E C;  2JA5 K;  4IO9 S;  2JA7 C;  1PJ6 A;  4JK1 A;  4KMA A;  3OPF A;  2FQO A;  1TWA A;  1HQM A;  2E2H C;  1XZP A;  3CF5 S;  2NVY C;  3A8J A;  1L0W A;  3HOX C;  3K7A C;  3GTG C;  4KAR A;  2E2H A;  2ZJR S;  2ZFZ A;  2YU9 A;  1BDF A;  3T00 A;  1WOO A;  2VUM K;  1IE0 A;  2P8T A;  4GTD A;  1R9T A;  3S1R C;  1V5V A;  4Y52 K;  3LPX A;  1TWH K;  5JFE A;  2E2I C;  4BBS K;  2A68 A;  4A3G C;  3I4N K;  2V6U A;  3AQO A;  4G0U A;  1WOS A;  3S2H K;  3GTK A;  5IYC K;  2ZUF A;  4KM8 A;  4WCE S;  2YU9 C;  2NVX K;  4GZY A;  1I6H C;  4Y7N K;  1J6X A;  3TFJ A;  4YFX A;  3K7A K;  1WCM A;  3S2H C;  1IBA A;  2B63 K;  5IP9 C;  3A8I A;  2NVQ K;  4XLN A;  1ZVU A;  5C44 C;  2E2I A;  1O29 A;  1TWC C;  1TWH A;  2P5M A;  3M4O K;  4G7Z A;  2Y0S L;  3GTJ C;  3BUE A;  1ZYR A;  4WIL A;  1O2F B;  3HOY C;  3A8K A;  2CFA A;  1ZQ1 C;  2WB1 L;  1XXB A;  5IOT A;  3S2D K;  5IYD K;  2VUM C;  3V4G A;  4C3J C;  2ZJQ S;  5IOR A;  3HOX K;  4Q5S A;  3GTP C;  3GSI A;  1SFO A;  2XCO A;  4A3L C;  4KAW X;  5EGE A;  1J98 A;  4C3I K;  2E2H K;  1TWF K;  1F7V A;  1TWA C;  2JH3 A;  2PMZ L;  1IW7 A;  3N0C A;  1BJT A;  1O2B A;  3AQP A;  4BKW A;  2WB1 D;  4YFN A;  1EQR A;  4YFK A;  4ZH4 A;  4IOA S;  2PPB A;  1YCL A;  1EI6 A;  4C3H K;  4KMH A;  4G0W A;  3HOU K;  1ISE A;  4WJ4 A;  4FZB A;  3AD8 C;  1R9T C;  4LJZ A;  3S1M C;  3PO2 K;  2NVX C;  4A3K K;  2JA5 A;  2R93 C;  1IQ0 A;  1WQF A;  3QX3 A;  1Y1W K;  1EH1 A;  4KB2 A;  4MEY A;  2GSN A;  1I6V A;  4A3G K;  3CQZ A;  1DCH A;  4BBR K;  2B63 A;  3DLL S;  1DCO A;  3GTL K;  4A3B K;  1TWF A;  1F9N A;  5IYD C;  5JVO A;  3S0X A;  4A3D C;  3HKZ D;  1UV7 A;  2GSO A;  3RZD C;  4GTB A;  4PAB A;  3ORE A;  1B4A A;  4C45 A;  3LAJ A;  1IL2 A;  2EBB A;  1SFO C;  4BBR C;  3S14 K;  1WSR A;  4A3I C;  3S14 C;  2JA6 C;  2CFA B;  2XCQ A;  1SFO K;  5TMC A;  4QJV B;  1I6H K;  4Y7N C;  1FEU A;  2R7Z A;  3GDZ A;  1SMY A;  2Y0S D;  2JA5 C;  3H3V D;  3S1Q C;  2NVX A;  4LOW A;  1WCM K;  3HOZ C;  1C0A A;  3GEE A;  3I4N C;  4A3M K;  4G7O A;  1JOE A;  4GFQ A;  5EGH A;  3FKI K;  3I4M C;  4P9S A;  2L5N A;  4OIR A;  4KN4 A;  2A6H A;  4KN7 A;  4A3K C;  3HOW C;  3GTK C;  3PO2 C;  2L3U A;  1WIH A;  2NVT K;  3CQZ K;  3GTL A;  4MQ9 A;  1DD5 A;  1TWG K;  1VRQ C;  2RH6 A;  4KAS A;  2R7Z K;  1XXA A;  3FHZ A;  1XXC A;  4KB4 A;  2ZJP S;  5FLM K;  5M3M K;  1EK8 A;  2WAQ D;  3HOY K;  3M3Y K;  5HL8 A;  3GTJ A;  3G4A A;  1TWF C;  3SZZ A;  5CJ9 A;  2NVT C;  3S16 C;  4A3F K;  3AD7 C;  1I50 C;  4C3I C;  1O27 A;  4YG2 A;  1YNN A;  3CQZ C;  1Y1V C;  5D4D A;  4LK1 A;  4LLG A;  3RZO K;  3TFH A;  1K83 A;  4Q4Z A;  3GTK K;  3EQL A;  1DCP A;  2R92 C;  4LR2 A;  3GTM K;  3GEI A;  4GT9 A;  3SZY A;  4WFB S;  2RGR A;  3GTJ K;  3FKI C;  1VGX A;  1TWC K;  1TWH C;  1TWC A;  5C44 K;  5L46 A;  3NUH A;  1JVI A;  2WAQ L;  1WCM C;  1XPP A;  3S1Q K;  2PA8 D;  2KXY A;  1PJ5 A;  1IS1 A;  4OIO A;  3MML B;  3GTO K;  1USM A;  4XSZ A;  5IYC C;  1PJ7 A;  5IOQ A;  5JVG S;  3S1N K;  1ZBS A;  3HOV C;  4AH6 A;  1I50 A;  1J6V A;  1RU0 A;  3GEH A;  3N0B A;  4A3C C;  4A3J C;  3IPJ A;  4BY1 K;  1VH2 A;  3S1R K;  4BY7 C;  4G7H A;  4A3D K;  2JA7 A;  2JA7 K;  3L4J A;  2D6F C;  4A3C K;  4WFA S;  4U67 S;  4DDQ A;  2GSU A;  1F93 A;  5TMF A;  3OEP A;  5TJ3 A;  3AH5 A;  2NVY A;  2PA8 L;  1YNJ A;  4QIW L;  5C4J K;  4KDD A;  4GTE A;  1Y1W C;  4KAT A;  2R92 A;  2R92 K;  3GTO C;  2R93 K;  4KC6 A;  3BP8 C;  4BXX C;  4XCH A;  3GTO A;  3S15 K;  1Y1W A;  3GTQ K;  3HXA A;  3GTM A;  1R9T K;  4KM9 A;  4GTC A;  4GTA A;  5HQH A;  1WQG A;  3G4C A;  1Y1V A;  4LK0 A;  4A93 K;  1Y1V K;  5M3F K;  4IOC S;  3DXJ A;  4C3H C;  3VA7 A;  1I3Q C;  1INN A;  1KQ4 A;  4FM9 A;  2JA8 C;  3GIR A;  4BXX K;  1TWA K;  3FOF A;  4X6A C;  2R7Z C;  1WQH A;  4GTF A;  1XZP B;  2CW0 A;  4P5B A;  3PIO S;  5C4J C;  3FOE A;  3H0G K;  1K83 C;  2GAH C;  1YX2 A;  3ERE D;  3RZO C;  3GTG A;  4A3L K;  4OIN A;  5M5W K;  2JA6 A;  2JA6 K;  3PO3 K;  1K83 K;  1BS2 A;  4C3J K;  4KMU A;  1TWG A;  2W7V A;  1VLO A;  1WOP A;  1WOR A;  3S2D C;  4AYB L;  3M3Y C;  2E2J C;  4RMF A;  1EFW A;  5HL7 S;  3TTG A;  3I4M K;  4G0V A;  5FLM C;  4AYB D;  4BLA A;  3S17 K;  2KQ1 A;  1XZQ B;  3HKZ L;  4A3J K;  2ZUE A;  3Q3Q A;  2A69 A;  1F7U A;  1X31 C;  3CAG A;  3M4O C;  2B63 C;  3WOD A;  3BP3 A;  2V6T A;  5CHP A;  3HOZ K;  3L4K A;  2NVQ C;  5IP9 K;  2FQT A;  4BLB A;  2YU9 K;  5IYB C;  2V6S A;  2PMZ D;  3S15 C;  2PHC B;  2R93 A;  4A3E K;  2XCR B;  5IYB K;  3GTQ A;  3AD9 C;  4MEX A;  4A3I K;  4LQY A;  3H3V L;  4OIP A;  4BBS C;  2E2I K;  1AB4 A;  2O5I A;  1O24 A;  5IP7 K;  4A3M C;  5IP7 C;  3PIP S;  3N3Y A;  2A6E A;  3T01 A;  5IOS A;  3S17 C;  1O28 A;  3LYW A;  4Y52 C;  4QJV A;  3GTM C;  3RZD K;  1ZXO A;  2E2J K;  4A3E C;  1JQW A;  3ADA C;  3T02 A;  1XZQ A;  4BY7 K;  4A3B C;  4BY1 C;  3H0G A;  3PO3 C; 
#chains in the Genus database with same CATH homology
 3GTL C;  3HOZ C;  2B63 K;  5IP9 C;  3I4N C;  2NVQ K;  3GTG K;  4A3M K;  3HOV K;  4XLN A;  4G7O A;  5C44 C;  4OIQ A;  3S1N C;  1TWC C;  5TMF A;  4A3F C;  2O5J A;  2NVY K;  3FKI K;  5M5Y K;  4G7Z A;  1YNJ A;  2PA8 L;  3H0G C;  4QIW L;  3M4O K;  5C4J K;  2Y0S L;  3GTJ C;  1ZYR A;  1Y1W C;  3I4M C;  2R92 K;  3GTO C;  3HOY C;  2R93 K;  4BXX C;  3S15 K;  3GTQ K;  5C3E K;  5C4X C;  2WB1 L;  4OIR A;  3S2D K;  4KN4 A;  2A6H A;  4KN7 A;  4QIW D;  2VUM C;  1R9T K;  5IYD K;  4A3K C;  1TWG C;  4C3J C;  3GTK C;  3HOW C;  4LK0 A;  3PO2 C;  1Y1V K;  5M3F K;  4A93 K;  3DXJ A;  3HOU C;  3HOX K;  5FJ8 K;  4Q5S A;  3PO2 K;  4C3H C;  1I3Q C;  3GTP C;  2NVT K;  3CQZ K;  4C2M C;  4MQ9 A;  4A3L C;  1TWG K;  3HOW K;  2JA8 C;  4C3I K;  2E2H K;  2R7Z K;  1TWF K;  3GTQ C;  1TWA C;  2BE5 A;  5FLM K;  2PMZ L;  1IW7 A;  4BXX K;  5M3M K;  4X6A K;  1TWA K;  3HOY K;  2WAQ D;  3M3Y K;  4X6A C;  2R7Z C;  2CW0 A;  2WB1 D;  4YFN A;  4YFK A;  5C4J C;  3H0G K;  4ZH4 A;  3S1M K;  1TWF C;  5M5X K;  1K83 C;  2NVT C;  3S16 C;  2PPB A;  3RZO C;  4A3F K;  3GTP K;  1I50 C;  4C3I C;  2JA8 K;  4C3H K;  4A3L K;  4YG2 A;  1YNN A;  3HOU K;  4XLP A;  3CQZ C;  1Y1V C;  5D4D A;  4C2M K;  4A3C K;  1I3Q K;  4NOI A;  4LK1 A;  4OIN A;  1I50 K;  5M5W K;  4LLG A;  2JA6 K;  3RZO K;  1R9T C;  1K83 K;  3PO3 K;  5C4X K;  4LJZ A;  4Q4Z A;  4XSX A;  5C3E C;  3S1M C;  4A93 C;  2NVX C;  4C3J K;  4KMU A;  4A3K K;  3GTK K;  2JA5 K;  3S2D C;  2JA7 C;  4AYB L;  3M3Y C;  2R93 C;  2E2J C;  3EQL A;  4JK1 A;  2R92 C;  3I4M K;  1Y1W K;  3GTM K;  5FLM C;  4AYB D;  4MEY A;  3S17 K;  4A3J K;  3HKZ L;  1HQM A;  1I6V A;  2E2H C;  2A69 A;  3GTJ K;  4A3G K;  3FKI C;  2NVY C;  2B63 C;  3M4O C;  1TWC K;  3WOD A;  1TWH C;  4BBR K;  5C44 K;  3GTL K;  3HOZ K;  3HOX C;  3K7A C;  2NVQ C;  3GTG C;  5IP9 K;  4A3B K;  2WAQ L;  2YU9 K;  5IYB C;  1BDF A;  2VUM K;  5IYD C;  1WCM C;  2PMZ D;  1XPP A;  3S15 C;  4A3D C;  3HKZ D;  3RZD C;  3S1Q K;  2PA8 D;  3PO3 C;  4A3E K;  4OIO A;  3GTO K;  5IYB K;  4XSZ A;  4MEX A;  5IYC C;  3S1R C;  4Y52 K;  4A3I K;  3S16 K;  3H3V L;  4OIP A;  4BY1 C;  4BBS C;  2E2I K;  1SFO C;  3S1N K;  4BBR C;  2O5I A;  1TWH K;  5IP7 K;  3S14 K;  2E2I C;  4BBS K;  3HOV C;  2A68 A;  4A3M C;  4A3G C;  4A3I C;  3I4N K;  5IP7 C;  3S14 C;  1SFO K;  5TMC A;  2A6E A;  4A3C C;  4A3J C;  3S17 C;  4QJV B;  4Y52 C;  4BY1 K;  3S2H K;  5IYC K;  3S1R K;  4QJV A;  4Y7N C;  3GTM C;  4BY7 C;  1I6H K;  4G7H A;  3RZD K;  4A3D K;  2E2J K;  1SMY A;  4A3E C;  2JA7 K;  2Y0S D;  2JA5 C;  3H3V D;  3S1Q C;  2YU9 C;  2NVX K;  4GZY A;  1I6H C;  4Y7N K;  4BY7 K;  4A3B C;  1WCM K;  4YFX A;  3K7A K;  3S2H C;  2JA6 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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