4LK1A

Crystal structure analysis of the e.coli holoenzyme
Total Genus 40
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase subunit alpha
publication title Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 40
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-07-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4lk1A02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4lk1A01
4NOIA 5C4JC 2JA6C 3H3VD 4BXXK 3GTOC 1ZYRA 4OIOA 4A93C 4KN7A 4XLPA 4A3JC 3HOUC 1I50K 2BE5A 3HOVK 3I4MK 4AYBD 4YFNA 3WODA 3S15K 3M3YC 1XPPA 5M3MK 3S16C 1YNJA 2R7ZK 3HOXC 2JA5C 3GTJK 2VUMK 5M5YK 4A3GC 4KN4A 1TWGK 3RZOC 3S17C 4BBRC 3GTKK 3HKZL 3M4OK 1Y1WC 2YU9C 3I4NC 2A69A 4MQ9A 2O5IA 4A3CC 4BY1C 2NVXK 4OIPA 3HOZC 5C44K 4OINA 3CQZK 4A3FK 5C4XK 4LK0A 1R9TC 4Q5SA 3S2HK 5IYCC 1TWCK 3GTLC 1TWFC 2WAQL 4X6AK 3FKIC 4A3BK 2A6HA 5TMFA 3GTPC 1SFOC 4A3EK 3S1NK 3S1MK 3GTGC 2R93C 4C3HC 3PO3C 4A3LK 2NVTC 1TWHK 3K7AK 4A3MK 4Y52K 4QJVB 5M3FK 4JK1A 1K83C 4C3JC 4C2MC 2JA7C 4G7OA 2PMZL 3H0GK 5C3EK 4Y7NK 4A3KK 3GTMK 4C3IK 3S14K 4Q4ZA 3HOYK 3H3VL 4OIQA 4G7HA 2Y0SD 2NVQC 5IP7K 3RZDK 2WB1D 4A3IC 3M4OC 2R92C 4BBSC 4QIWL 2E2JK 5IYBK 3HOWC 3PO2K 5D4DA 1I6HK 4AYBL 4OIRA 1Y1VK 3S1RK 2B63K 1WCMK 5IP9K 4ZH4A 4A3DC 2PPBA 5IYDK 2E2HC 3S1QC 5C4JK 4BY7C 2JA8C 2JA6K 4YFXA 3GTOK 4A93K 2NVYC 4A3JK 4XSZA 3HOUK 2E2IK 5FLMC 1TWAC 3HKZD 3S2DC 1I3QC 2E2IC 4KMUA 3M3YK 4LK1A 4GZYA 4BXXC 3S16K 3HOVC 1I50C 3I4MC 3HOXK 2JA5K 1BDFA 3S15C 4A3GK 4LLGA 2PA8D 3RZOK 3S17K 4BBRK 4MEXA 2A6EA 4QJVA 1Y1WK 2CW0A 2YU9K 3I4NK 4A3CK 2R7ZC 3EQLA 4BY1K 3GTJC 2VUMC 3HOZK 3GTQC 1TWGC 2E2HK 1R9TK 5IYCK 3GTKC 3GTLK 1TWFK 1SMYA 3FKIK 2NVXC 2A68A 5FJ8K 3GTPK 5C44C 1HQMA 3CQZC 4A3FC 5C4XC 1SFOK 3GTGK 4BBSK 2R93K 3S2HC 2Y0SL 4C3HK 1TWCC 4QIWD 2WB1L 4X6AC 2NVTK 4A3BC 3PO3K 1K83K 4C3JK 4C2MK 2JA7K 1YNNA 4A3EC 3S1NC 1IW7A 3S1MC 4LJZA 4G7ZA 5M5XK 4YFKA 4A3LC 2O5JA 5M5WK 2NVQK 1TWHC 1I6VA 3K7AC 4A3MC 2WAQD 4MEYA 4Y52C 4A3IK 3H0GC 2R92K 3GTQK 5C3EC 3HOWK 4Y7NC 4A3KC 3GTMC 4C3IC 3S14C 3HOYC 4A3DK 5IP7C 4YG2A 3RZDC 3S1QK 4XLNA 2JA8K 2E2JC 5TMCA 5IYBC 3PO2C 1I6HC 4BY7K 3DXJA 2NVYK 1Y1VC 4XSXA 2PMZD 3S1RC 2B63C 1WCMC 2PA8L 1TWAK 5FLMK 3S2DK 1I3QK 5IP9C 5IYDC
chains in the Genus database with same CATH superfamily
1B4AA 4GT9A 1F7UA 3GTOC 3I4MK 3GTPA 3S15K 3WODA 3SZZA 1PJ7A 4AH6A 4PABA 5JVOA 3TTGA 1YNJA 2R7ZK 4IOCS 1XZPA 3LAPA 2Y3PA 3S17C 4P5AA 1O2AA 4A3CC 4KC6A 4BY1C 5E68A 1VJEA 4OINA 4LK0A 5IYCC 1TWFC 1DD5A 3FKIC 1B4BA 2E2IA 3PO3C 4O2DA 3FOEA 4A3MK 4Y52K 4QJVB 3H0GK 4C3JC 4G7OA 3GTMK 2ZUFA 2GSUA 4KMAA 1O27A 2GAHC 1K83A 1BS2A 1F9NA 4KB4A 5IP7K 1IL2A 3LYWA 2WB1D 3M4OC 4QIWL 3GEHA 3S1RK 1WORA 1INNA 3GSIA 5IP9K 2PPBA 1O26A 2JA6K 4BY7C 2JA8C 1YCLA 5TJ3A 1ZQ1C 3CAGA 3M3YK 5IOQA 4KASA 3S16K 3I4MC 2CFAA 1BDFA 3T00A 3PIOS 3S15C 3AQPA 4KM9A 1I50A 2L3UA 3LAJA 4BBRK 2A6EA 1O24A 2R7ZC 3A8KA 1C0AA 1IQ0A 4GTFA 3NUHA 3GTLK 1ZXOA 1SMYA 1J6VA 1FEUA 1DCOA 5IOTA 1Y1VA 3V4GA 5FJ8K 1SFOK 1XXCA 2WB1L 4C3HK 3CQZA 4GTCA 1K83K 5DM6S 2D6FC 1YNNA 4PAAA 4YFKA 3S0XA 3T02A 4A3MC 2WAQD 4Y52C 3H0GC 3HOWK 3GTMC 5IP7C 3S1QK 2YU9A 2W7VA 4GTBA 4XSXA 2PMZD 3S1RC 5FLMK 1IBAA 1VH2A 1I3QK 5IP9C 3S2DK 2JA6C 1O2FB 3ERED 4G0WA 1ZYRA 4OIOA 1I50K 2XCQA 4P5BA 1WQFA 3TFJA 4AYBD 4YFNA 2PHCB 3M3YC 3GEEA 4KB2A 3S16C 2L5NA 2JA7A 1TWGK 4LOWA 4BBRC 2R92A 2A69A 4MQ9A 3AD9C 2KQ1A 5C44K 3CQZK 5C4XK 4Q5SA 4XCHA 3GTLC 2WAQL 3AQOA 2E2HA 1VGXA 2NVYA 3GIRA 1SFOC 4A3EK 1TWAA 2FQTA 4C3HC 1O29A 2P8TA 4A3LK 1TWHK 2V6UA 3N3YA 3GTGA 5M3FK 4JK1A 1K83C 2PMZL 4Y7NK 4A3KK 4C3IK 3S14K 1XXBA 2Y0SD 3RZDK 2E2JK 1I6HK 5IYBK 3HOWC 5D4DA 4AYBL 4M1XA 2JH3A 3GTQA 3Q3QA 3S1QC 4FZBA 1WQGA 2NVXA 4A3JK 3OREA 5FLMC 2ZJRS 3HKZD 3S2DC 1I3QC 4LK1A 4G0VA 3QX3A 1I50C 1UV7A 3HOXK 2JA5K 4KMDA 4A3GK 1KQ4A 1XZQB 2PA8D 1Y1WK 2CW0A 4BKWA 3GDZA 3EQLA 3HOZK 1TWGC 1XXAA 2E2HK 4KDDA 1R9TK 1JQWA 3GTJA 2VUMA 5EGHA 1EQRA 1EH1A 2A68A 3GTPK 5C44C 3CQZC 5C4XC 1WCMA 3GTGK 2Y0SL 1WOSA 2NVTK 3G4AA 1F93A 5CJ9A 1TWCA 4C2MK 1G51A 4A3EC 4WJ3M 4A3LC 1TWHC 4A3IK 4LQYA 1GE9A 3GTQK 4BBSK 3FHZA 1USMA 4Y7NC 4A3KC 1F7VA 3JSTA 4C3IC 3S14C 4J3NA 2KPUA 3RZDC 1JOEA 2E2JC 5TMCA 5IYBC 1I6HC 3L4JA 3DXJA 3N0CA 2PA8L 3TFHA 2E2IK 3FKIA 4BXXK 4XLPA 4A3JC 2BE5A 1JVIA 1XPPA 1HI9A 1V5VA 3HOXC 2ZJQS 2JA5C 4U67S 3GTJK 2VUMK 4A3GC 1J98A 1Y1WC 2RGRA 3HOZC 1R9TC 1TWCK 2XCOA 1YX2A 3G4CA 5TMFA 3GTPC 4P9SA 3S1NK 5L46A 3GTGC 1WSRA 4IO9S 2NVTC 4G0UA 3K7AK 2R93A 4WFAS 4C2MC 5C3EK 3AD7C 3OPFA 2KXYA 2GSNA 4A3IC 4ILDA 4BBSC 5JFEA 3PO2K 2R7ZA 4OIRA 1Y1VK 1WOOA 1PJ5A 4ZH4A 1DCPA 5C4JK 1RU0A 4YFXA 4A93K 3HOUK 4XSZA 2E2IC 4KMUA 4BXXC 4GTEA 3VA7A 4WFBS 4LLGA 3MMLB 3RZOK 2ZFZA 5HL7S 4MEXA 4QJVA 1XZQA 2YU9K 3I4NK 3H0GA 2KWAA 1WOPA 3LPXA 3GTMA 4KARA 3GTJC 2VUMC 4LR2A 4WJ4A 1VRQC 1EFWA 3CF5S 4WCES 3GTKA 1WQHA 2R93K 1TWCC 4QIWD 1BJTA 4RMFA 2JA6A 2RH6A 3BP3A 2JA7K 5JVGS 1ZVUA 3S1NC 1IW7A 4LJZA 4G7ZA 1EK8A 2O5JA 3L4KA 3OEPA 2NVQK 1I6VA 3K7AC 4MEYA 2R92K 5C3EC 4IOAS 5IORA 4A3DK 4YG2A 3AD8C 4XLNA 4GTAA 3PO2C 4BLAA 2NVYK 1Y1VC 1O25A 1TWAK 3GTLA 4NOIA 5C4JC 3H3VD 2B63A 1IS1A 4A93C 4KN7A 3HOUC 3HOVK 1SFOA 3GTOA 1XZPB 5M3MK 3DLLS 2EBBA 1VLOA 3GEIA 3BP8C 5M5YK 4KN4A 1WSVA 3RZOC 4WILA 3GTKK 4C45A 3HKZL 2YU9C 3I4NC 2O5IA 4WF9S 1ZBSA 5HL8A 2NVXK 4OIPA 2GAGC 3PIPS 3BUEA 4A3FK 2ZUEA 3S2HK 5CHPA 4X6AK 4A3BK 4GTDA 2A6HA 1TWFA 3AH5A 3S1MK 2R93C 1I3QA 1DCHA 4KMHA 2P5MA 2JA7C 3FOFA 4Q4ZA 2FQOA 3HOYK 3H3VL 4OIQA 4G7HA 4KM8A 2NVQC 3TFIA 2R92C 1X31C 1PJ6A 5EGEA 3A8JA 1TWGA 3A8IA 2B63K 1J6WA 1WCMK 2GSOA 1L0WA 4A3DC 1IE0A 5IYDK 2E2HC 3HXAA 1O2BA 3GTOK 2NVYC 2V6TA 1TWAC 2CFAB 4GZYA 4KAWX 5JVHS 3HOVC 3SZYA 4KATA 4DDQA 3S17K 4FM9A 1TWHA 4A3CK 1O28A 2XCRB 4BY1K 1AB4A 4GFQA 3GTQC 5IYCK 3GTKC 1TWFK 3FKIK 3ADAC 2NVXC 1WIHA 1HQMA 4A3FC 3S2HC 3PO3K 1USOA 3N0BA 4X6AC 4A3BC 4BLBA 1BGWA 4GTLA 4C3JK 3S1MC 5M5XK 1EI6A 5M5WK 3M4OK 5HQHA 2JA5A 2ZJPS 1J6XA 5IOSA 4WFNS 3HOYC 1Y1WA 4BY7K 2JA8K 3T01A 1ISEA 5DM7S 2B63C 1WCMC 2V6SA 1R9TA 5IYDC 3IPJA
chains in the Genus database with same CATH topology
4NOIA 5C4JC 2JA6C 3H3VD 4BXXK 3GTOC 1ZYRA 4OIOA 4A93C 4KN7A 4XLPA 4A3JC 3HOUC 1I50K 2BE5A 3HOVK 3I4MK 4AYBD 4YFNA 3WODA 3S15K 3M3YC 1XPPA 5M3MK 3S16C 1YNJA 2R7ZK 3HOXC 2JA5C 3GTJK 2VUMK 5M5YK 4A3GC 4KN4A 1TWGK 3RZOC 3S17C 4BBRC 3GTKK 3HKZL 3M4OK 1Y1WC 2YU9C 3I4NC 2A69A 4MQ9A 2O5IA 4A3CC 4BY1C 2NVXK 4OIPA 3HOZC 5C44K 4OINA 3CQZK 4A3FK 5C4XK 4LK0A 1R9TC 4Q5SA 3S2HK 5IYCC 1TWCK 3GTLC 1TWFC 2WAQL 4X6AK 3FKIC 4A3BK 2A6HA 5TMFA 3GTPC 1SFOC 4A3EK 3S1NK 3S1MK 3GTGC 2R93C 4C3HC 3PO3C 4A3LK 2NVTC 1TWHK 3K7AK 4A3MK 4Y52K 4QJVB 5M3FK 4JK1A 1K83C 4C3JC 4C2MC 2JA7C 4G7OA 2PMZL 3H0GK 5C3EK 4Y7NK 4A3KK 3GTMK 4C3IK 3S14K 4Q4ZA 3HOYK 3H3VL 4OIQA 4G7HA 2Y0SD 2NVQC 5IP7K 3RZDK 2WB1D 4A3IC 3M4OC 2R92C 4BBSC 4QIWL 2E2JK 5IYBK 3HOWC 3PO2K 5D4DA 1I6HK 4AYBL 4OIRA 1Y1VK 3S1RK 2B63K 1WCMK 5IP9K 4ZH4A 4A3DC 2PPBA 5IYDK 2E2HC 3S1QC 5C4JK 4BY7C 2JA8C 2JA6K 4YFXA 3GTOK 4A93K 2NVYC 4A3JK 4XSZA 3HOUK 2E2IK 5FLMC 1TWAC 3HKZD 3S2DC 1I3QC 2E2IC 4KMUA 3M3YK 4LK1A 4GZYA 4BXXC 3S16K 3HOVC 1I50C 3I4MC 3HOXK 2JA5K 1BDFA 3S15C 4A3GK 4LLGA 2PA8D 3RZOK 3S17K 4BBRK 4MEXA 2A6EA 4QJVA 1Y1WK 2CW0A 2YU9K 3I4NK 4A3CK 2R7ZC 3EQLA 4BY1K 3GTJC 2VUMC 3HOZK 3GTQC 1TWGC 2E2HK 1R9TK 5IYCK 3GTKC 3GTLK 1TWFK 1SMYA 3FKIK 2NVXC 2A68A 5FJ8K 3GTPK 5C44C 1HQMA 3CQZC 4A3FC 5C4XC 1SFOK 3GTGK 4BBSK 2R93K 3S2HC 2Y0SL 4C3HK 1TWCC 4QIWD 2WB1L 4X6AC 2NVTK 4A3BC 3PO3K 1K83K 4C3JK 4C2MK 2JA7K 1YNNA 4A3EC 3S1NC 1IW7A 3S1MC 4LJZA 4G7ZA 5M5XK 4YFKA 4A3LC 2O5JA 5M5WK 2NVQK 1TWHC 1I6VA 3K7AC 4A3MC 2WAQD 4MEYA 4Y52C 4A3IK 3H0GC 2R92K 3GTQK 5C3EC 3HOWK 4Y7NC 4A3KC 3GTMC 4C3IC 3S14C 3HOYC 4A3DK 5IP7C 4YG2A 3RZDC 3S1QK 4XLNA 2JA8K 2E2JC 5TMCA 5IYBC 3PO2C 1I6HC 4BY7K 3DXJA 2NVYK 1Y1VC 4XSXA 2PMZD 3S1RC 2B63C 1WCMC 2PA8L 1TWAK 5FLMK 3S2DK 1I3QK 5IP9C 5IYDC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NOI A;  5C4J C;  2JA6 C;  3H3V D;  4BXX K;  3GTO C;  1ZYR A;  4OIO A;  4A93 C;  4KN7 A;  4XLP A;  4A3J C;  3HOU C;  1I50 K;  2BE5 A;  3HOV K;  3I4M K;  4AYB D;  4YFN A;  3WOD A;  3S15 K;  3M3Y C;  1XPP A;  5M3M K;  3S16 C;  1YNJ A;  2R7Z K;  3HOX C;  2JA5 C;  3GTJ K;  2VUM K;  5M5Y K;  4A3G C;  4KN4 A;  1TWG K;  3RZO C;  3S17 C;  4BBR C;  3GTK K;  3HKZ L;  3M4O K;  1Y1W C;  2YU9 C;  3I4N C;  2A69 A;  4MQ9 A;  2O5I A;  4A3C C;  4BY1 C;  2NVX K;  4OIP A;  3HOZ C;  5C44 K;  4OIN A;  3CQZ K;  4A3F K;  5C4X K;  4LK0 A;  1R9T C;  4Q5S A;  3S2H K;  5IYC C;  1TWC K;  3GTL C;  1TWF C;  2WAQ L;  4X6A K;  3FKI C;  4A3B K;  2A6H A;  5TMF A;  3GTP C;  1SFO C;  4A3E K;  3S1N K;  3S1M K;  3GTG C;  2R93 C;  4C3H C;  3PO3 C;  4A3L K;  2NVT C;  1TWH K;  3K7A K;  4A3M K;  4Y52 K;  4QJV B;  5M3F K;  4JK1 A;  1K83 C;  4C3J C;  4C2M C;  2JA7 C;  4G7O A;  2PMZ L;  3H0G K;  5C3E K;  4Y7N K;  4A3K K;  3GTM K;  4C3I K;  3S14 K;  4Q4Z A;  3HOY K;  3H3V L;  4OIQ A;  4G7H A;  2Y0S D;  2NVQ C;  5IP7 K;  3RZD K;  2WB1 D;  4A3I C;  3M4O C;  2R92 C;  4BBS C;  4QIW L;  2E2J K;  5IYB K;  3HOW C;  3PO2 K;  5D4D A;  1I6H K;  4AYB L;  4OIR A;  1Y1V K;  3S1R K;  2B63 K;  1WCM K;  5IP9 K;  4ZH4 A;  4A3D C;  2PPB A;  5IYD K;  2E2H C;  3S1Q C;  5C4J K;  4BY7 C;  2JA8 C;  2JA6 K;  4YFX A;  3GTO K;  4A93 K;  2NVY C;  4A3J K;  4XSZ A;  3HOU K;  2E2I K;  5FLM C;  1TWA C;  3HKZ D;  3S2D C;  1I3Q C;  2E2I C;  4KMU A;  3M3Y K;  4LK1 A;  4GZY A;  4BXX C;  3S16 K;  3HOV C;  1I50 C;  3I4M C;  3HOX K;  2JA5 K;  1BDF A;  3S15 C;  4A3G K;  4LLG A;  2PA8 D;  3RZO K;  3S17 K;  4BBR K;  4MEX A;  2A6E A;  4QJV A;  1Y1W K;  2CW0 A;  2YU9 K;  3I4N K;  4A3C K;  2R7Z C;  3EQL A;  4BY1 K;  3GTJ C;  2VUM C;  3HOZ K;  3GTQ C;  1TWG C;  2E2H K;  1R9T K;  5IYC K;  3GTK C;  3GTL K;  1TWF K;  1SMY A;  3FKI K;  2NVX C;  2A68 A;  5FJ8 K;  3GTP K;  5C44 C;  1HQM A;  3CQZ C;  4A3F C;  5C4X C;  1SFO K;  3GTG K;  4BBS K;  2R93 K;  3S2H C;  2Y0S L;  4C3H K;  1TWC C;  4QIW D;  2WB1 L;  4X6A C;  2NVT K;  4A3B C;  3PO3 K;  1K83 K;  4C3J K;  4C2M K;  2JA7 K;  1YNN A;  4A3E C;  3S1N C;  1IW7 A;  3S1M C;  4LJZ A;  4G7Z A;  5M5X K;  4YFK A;  4A3L C;  2O5J A;  5M5W K;  2NVQ K;  1TWH C;  1I6V A;  3K7A C;  4A3M C;  2WAQ D;  4MEY A;  4Y52 C;  4A3I K;  3H0G C;  2R92 K;  3GTQ K;  5C3E C;  3HOW K;  4Y7N C;  4A3K C;  3GTM C;  4C3I C;  3S14 C;  3HOY C;  4A3D K;  5IP7 C;  4YG2 A;  3RZD C;  3S1Q K;  4XLN A;  2JA8 K;  2E2J C;  5TMC A;  5IYB C;  3PO2 C;  1I6H C;  4BY7 K;  3DXJ A;  2NVY K;  1Y1V C;  4XSX A;  2PMZ D;  3S1R C;  2B63 C;  1WCM C;  2PA8 L;  1TWA K;  5FLM K;  3S2D K;  1I3Q K;  5IP9 C;  5IYD C; 
#chains in the Genus database with same CATH topology
 1B4A A;  4GT9 A;  1F7U A;  3GTO C;  3I4M K;  3GTP A;  3S15 K;  3WOD A;  3SZZ A;  1PJ7 A;  4AH6 A;  4PAB A;  5JVO A;  3TTG A;  1YNJ A;  2R7Z K;  4IOC S;  1XZP A;  3LAP A;  2Y3P A;  3S17 C;  4P5A A;  1O2A A;  4A3C C;  4KC6 A;  4BY1 C;  5E68 A;  1VJE A;  4OIN A;  4LK0 A;  5IYC C;  1TWF C;  1DD5 A;  3FKI C;  1B4B A;  2E2I A;  3PO3 C;  4O2D A;  3FOE A;  4A3M K;  4Y52 K;  4QJV B;  3H0G K;  4C3J C;  4G7O A;  3GTM K;  2ZUF A;  2GSU A;  4KMA A;  1O27 A;  2GAH C;  1K83 A;  1BS2 A;  1F9N A;  4KB4 A;  5IP7 K;  1IL2 A;  3LYW A;  2WB1 D;  3M4O C;  4QIW L;  3GEH A;  3S1R K;  1WOR A;  1INN A;  3GSI A;  5IP9 K;  2PPB A;  1O26 A;  2JA6 K;  4BY7 C;  2JA8 C;  1YCL A;  5TJ3 A;  1ZQ1 C;  3CAG A;  3M3Y K;  5IOQ A;  4KAS A;  3S16 K;  3I4M C;  2CFA A;  1BDF A;  3T00 A;  3PIO S;  3S15 C;  3AQP A;  4KM9 A;  1I50 A;  2L3U A;  3LAJ A;  4BBR K;  2A6E A;  1O24 A;  2R7Z C;  3A8K A;  1C0A A;  1IQ0 A;  4GTF A;  3NUH A;  3GTL K;  1ZXO A;  1SMY A;  1J6V A;  1FEU A;  1DCO A;  5IOT A;  1Y1V A;  3V4G A;  5FJ8 K;  1SFO K;  1XXC A;  2WB1 L;  4C3H K;  3CQZ A;  4GTC A;  1K83 K;  5DM6 S;  2D6F C;  1YNN A;  4PAA A;  4YFK A;  3S0X A;  3T02 A;  4A3M C;  2WAQ D;  4Y52 C;  3H0G C;  3HOW K;  3GTM C;  5IP7 C;  3S1Q K;  2YU9 A;  2W7V A;  4GTB A;  4XSX A;  2PMZ D;  3S1R C;  5FLM K;  1IBA A;  1VH2 A;  1I3Q K;  5IP9 C;  3S2D K;  2JA6 C;  1O2F B;  3ERE D;  4G0W A;  1ZYR A;  4OIO A;  1I50 K;  2XCQ A;  4P5B A;  1WQF A;  3TFJ A;  4AYB D;  4YFN A;  2PHC B;  3M3Y C;  3GEE A;  4KB2 A;  3S16 C;  2L5N A;  2JA7 A;  1TWG K;  4LOW A;  4BBR C;  2R92 A;  2A69 A;  4MQ9 A;  3AD9 C;  2KQ1 A;  5C44 K;  3CQZ K;  5C4X K;  4Q5S A;  4XCH A;  3GTL C;  2WAQ L;  3AQO A;  2E2H A;  1VGX A;  2NVY A;  3GIR A;  1SFO C;  4A3E K;  1TWA A;  2FQT A;  4C3H C;  1O29 A;  2P8T A;  4A3L K;  1TWH K;  2V6U A;  3N3Y A;  3GTG A;  5M3F K;  4JK1 A;  1K83 C;  2PMZ L;  4Y7N K;  4A3K K;  4C3I K;  3S14 K;  1XXB A;  2Y0S D;  3RZD K;  2E2J K;  1I6H K;  5IYB K;  3HOW C;  5D4D A;  4AYB L;  4M1X A;  2JH3 A;  3GTQ A;  3Q3Q A;  3S1Q C;  4FZB A;  1WQG A;  2NVX A;  4A3J K;  3ORE A;  5FLM C;  2ZJR S;  3HKZ D;  3S2D C;  1I3Q C;  4LK1 A;  4G0V A;  3QX3 A;  1I50 C;  1UV7 A;  3HOX K;  2JA5 K;  4KMD A;  4A3G K;  1KQ4 A;  1XZQ B;  2PA8 D;  1Y1W K;  2CW0 A;  4BKW A;  3GDZ A;  3EQL A;  3HOZ K;  1TWG C;  1XXA A;  2E2H K;  4KDD A;  1R9T K;  1JQW A;  3GTJ A;  2VUM A;  5EGH A;  1EQR A;  1EH1 A;  2A68 A;  3GTP K;  5C44 C;  3CQZ C;  5C4X C;  1WCM A;  3GTG K;  2Y0S L;  1WOS A;  2NVT K;  3G4A A;  1F93 A;  5CJ9 A;  1TWC A;  4C2M K;  1G51 A;  4A3E C;  4WJ3 M;  4A3L C;  1TWH C;  4A3I K;  4LQY A;  1GE9 A;  3GTQ K;  4BBS K;  3FHZ A;  1USM A;  4Y7N C;  4A3K C;  1F7V A;  3JST A;  4C3I C;  3S14 C;  4J3N A;  2KPU A;  3RZD C;  1JOE A;  2E2J C;  5TMC A;  5IYB C;  1I6H C;  3L4J A;  3DXJ A;  3N0C A;  2PA8 L;  3TFH A;  2E2I K;  3FKI A;  4BXX K;  4XLP A;  4A3J C;  2BE5 A;  1JVI A;  1XPP A;  1HI9 A;  1V5V A;  3HOX C;  2ZJQ S;  2JA5 C;  4U67 S;  3GTJ K;  2VUM K;  4A3G C;  1J98 A;  1Y1W C;  2RGR A;  3HOZ C;  1R9T C;  1TWC K;  2XCO A;  1YX2 A;  3G4C A;  5TMF A;  3GTP C;  4P9S A;  3S1N K;  5L46 A;  3GTG C;  1WSR A;  4IO9 S;  2NVT C;  4G0U A;  3K7A K;  2R93 A;  4WFA S;  4C2M C;  5C3E K;  3AD7 C;  3OPF A;  2KXY A;  2GSN A;  4A3I C;  4ILD A;  4BBS C;  5JFE A;  3PO2 K;  2R7Z A;  4OIR A;  1Y1V K;  1WOO A;  1PJ5 A;  4ZH4 A;  1DCP A;  5C4J K;  1RU0 A;  4YFX A;  4A93 K;  3HOU K;  4XSZ A;  2E2I C;  4KMU A;  4BXX C;  4GTE A;  3VA7 A;  4WFB S;  4LLG A;  3MML B;  3RZO K;  2ZFZ A;  5HL7 S;  4MEX A;  4QJV A;  1XZQ A;  2YU9 K;  3I4N K;  3H0G A;  2KWA A;  1WOP A;  3LPX A;  3GTM A;  4KAR A;  3GTJ C;  2VUM C;  4LR2 A;  4WJ4 A;  1VRQ C;  1EFW A;  3CF5 S;  4WCE S;  3GTK A;  1WQH A;  2R93 K;  1TWC C;  4QIW D;  1BJT A;  4RMF A;  2JA6 A;  2RH6 A;  3BP3 A;  2JA7 K;  5JVG S;  1ZVU A;  3S1N C;  1IW7 A;  4LJZ A;  4G7Z A;  1EK8 A;  2O5J A;  3L4K A;  3OEP A;  2NVQ K;  1I6V A;  3K7A C;  4MEY A;  2R92 K;  5C3E C;  4IOA S;  5IOR A;  4A3D K;  4YG2 A;  3AD8 C;  4XLN A;  4GTA A;  3PO2 C;  4BLA A;  2NVY K;  1Y1V C;  1O25 A;  1TWA K;  3GTL A;  4NOI A;  5C4J C;  3H3V D;  2B63 A;  1IS1 A;  4A93 C;  4KN7 A;  3HOU C;  3HOV K;  1SFO A;  3GTO A;  1XZP B;  5M3M K;  3DLL S;  2EBB A;  1VLO A;  3GEI A;  3BP8 C;  5M5Y K;  4KN4 A;  1WSV A;  3RZO C;  4WIL A;  3GTK K;  4C45 A;  3HKZ L;  2YU9 C;  3I4N C;  2O5I A;  4WF9 S;  1ZBS A;  5HL8 A;  2NVX K;  4OIP A;  2GAG C;  3PIP S;  3BUE A;  4A3F K;  2ZUE A;  3S2H K;  5CHP A;  4X6A K;  4A3B K;  4GTD A;  2A6H A;  1TWF A;  3AH5 A;  3S1M K;  2R93 C;  1I3Q A;  1DCH A;  4KMH A;  2P5M A;  2JA7 C;  3FOF A;  4Q4Z A;  2FQO A;  3HOY K;  3H3V L;  4OIQ A;  4G7H A;  4KM8 A;  2NVQ C;  3TFI A;  2R92 C;  1X31 C;  1PJ6 A;  5EGE A;  3A8J A;  1TWG A;  3A8I A;  2B63 K;  1J6W A;  1WCM K;  2GSO A;  1L0W A;  4A3D C;  1IE0 A;  5IYD K;  2E2H C;  3HXA A;  1O2B A;  3GTO K;  2NVY C;  2V6T A;  1TWA C;  2CFA B;  4GZY A;  4KAW X;  5JVH S;  3HOV C;  3SZY A;  4KAT A;  4DDQ A;  3S17 K;  4FM9 A;  1TWH A;  4A3C K;  1O28 A;  2XCR B;  4BY1 K;  1AB4 A;  4GFQ A;  3GTQ C;  5IYC K;  3GTK C;  1TWF K;  3FKI K;  3ADA C;  2NVX C;  1WIH A;  1HQM A;  4A3F C;  3S2H C;  3PO3 K;  1USO A;  3N0B A;  4X6A C;  4A3B C;  4BLB A;  1BGW A;  4GTL A;  4C3J K;  3S1M C;  5M5X K;  1EI6 A;  5M5W K;  3M4O K;  5HQH A;  2JA5 A;  2ZJP S;  1J6X A;  5IOS A;  4WFN S;  3HOY C;  1Y1W A;  4BY7 K;  2JA8 K;  3T01 A;  1ISE A;  5DM7 S;  2B63 C;  1WCM C;  2V6S A;  1R9T A;  5IYD C;  3IPJ A; 
#chains in the Genus database with same CATH homology
 4NOI A;  5C4J C;  2JA6 C;  3H3V D;  4BXX K;  3GTO C;  1ZYR A;  4OIO A;  4A93 C;  4KN7 A;  4XLP A;  4A3J C;  3HOU C;  1I50 K;  2BE5 A;  3HOV K;  3I4M K;  4AYB D;  4YFN A;  3WOD A;  3S15 K;  3M3Y C;  1XPP A;  5M3M K;  3S16 C;  1YNJ A;  2R7Z K;  3HOX C;  2JA5 C;  3GTJ K;  2VUM K;  5M5Y K;  4A3G C;  4KN4 A;  1TWG K;  3RZO C;  3S17 C;  4BBR C;  3GTK K;  3HKZ L;  3M4O K;  1Y1W C;  2YU9 C;  3I4N C;  2A69 A;  4MQ9 A;  2O5I A;  4A3C C;  4BY1 C;  2NVX K;  4OIP A;  3HOZ C;  5C44 K;  4OIN A;  3CQZ K;  4A3F K;  5C4X K;  4LK0 A;  1R9T C;  4Q5S A;  3S2H K;  5IYC C;  1TWC K;  3GTL C;  1TWF C;  2WAQ L;  4X6A K;  3FKI C;  4A3B K;  2A6H A;  5TMF A;  3GTP C;  1SFO C;  4A3E K;  3S1N K;  3S1M K;  3GTG C;  2R93 C;  4C3H C;  3PO3 C;  4A3L K;  2NVT C;  1TWH K;  3K7A K;  4A3M K;  4Y52 K;  4QJV B;  5M3F K;  4JK1 A;  1K83 C;  4C3J C;  4C2M C;  2JA7 C;  4G7O A;  2PMZ L;  3H0G K;  5C3E K;  4Y7N K;  4A3K K;  3GTM K;  4C3I K;  3S14 K;  4Q4Z A;  3HOY K;  3H3V L;  4OIQ A;  4G7H A;  2Y0S D;  2NVQ C;  5IP7 K;  3RZD K;  2WB1 D;  4A3I C;  3M4O C;  2R92 C;  4BBS C;  4QIW L;  2E2J K;  5IYB K;  3HOW C;  3PO2 K;  5D4D A;  1I6H K;  4AYB L;  4OIR A;  1Y1V K;  3S1R K;  2B63 K;  1WCM K;  5IP9 K;  4ZH4 A;  4A3D C;  2PPB A;  5IYD K;  2E2H C;  3S1Q C;  5C4J K;  4BY7 C;  2JA8 C;  2JA6 K;  4YFX A;  3GTO K;  4A93 K;  2NVY C;  4A3J K;  4XSZ A;  3HOU K;  2E2I K;  5FLM C;  1TWA C;  3HKZ D;  3S2D C;  1I3Q C;  2E2I C;  4KMU A;  3M3Y K;  4LK1 A;  4GZY A;  4BXX C;  3S16 K;  3HOV C;  1I50 C;  3I4M C;  3HOX K;  2JA5 K;  1BDF A;  3S15 C;  4A3G K;  4LLG A;  2PA8 D;  3RZO K;  3S17 K;  4BBR K;  4MEX A;  2A6E A;  4QJV A;  1Y1W K;  2CW0 A;  2YU9 K;  3I4N K;  4A3C K;  2R7Z C;  3EQL A;  4BY1 K;  3GTJ C;  2VUM C;  3HOZ K;  3GTQ C;  1TWG C;  2E2H K;  1R9T K;  5IYC K;  3GTK C;  3GTL K;  1TWF K;  1SMY A;  3FKI K;  2NVX C;  2A68 A;  5FJ8 K;  3GTP K;  5C44 C;  1HQM A;  3CQZ C;  4A3F C;  5C4X C;  1SFO K;  3GTG K;  4BBS K;  2R93 K;  3S2H C;  2Y0S L;  4C3H K;  1TWC C;  4QIW D;  2WB1 L;  4X6A C;  2NVT K;  4A3B C;  3PO3 K;  1K83 K;  4C3J K;  4C2M K;  2JA7 K;  1YNN A;  4A3E C;  3S1N C;  1IW7 A;  3S1M C;  4LJZ A;  4G7Z A;  5M5X K;  4YFK A;  4A3L C;  2O5J A;  5M5W K;  2NVQ K;  1TWH C;  1I6V A;  3K7A C;  4A3M C;  2WAQ D;  4MEY A;  4Y52 C;  4A3I K;  3H0G C;  2R92 K;  3GTQ K;  5C3E C;  3HOW K;  4Y7N C;  4A3K C;  3GTM C;  4C3I C;  3S14 C;  3HOY C;  4A3D K;  5IP7 C;  4YG2 A;  3RZD C;  3S1Q K;  4XLN A;  2JA8 K;  2E2J C;  5TMC A;  5IYB C;  3PO2 C;  1I6H C;  4BY7 K;  3DXJ A;  2NVY K;  1Y1V C;  4XSX A;  2PMZ D;  3S1R C;  2B63 C;  1WCM C;  2PA8 L;  1TWA K;  5FLM K;  3S2D K;  1I3Q K;  5IP9 C;  5IYD C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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