4LK1A

Crystal structure analysis of the e.coli holoenzyme
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase subunit alpha
molecule tags Transferase
source organism Escherichia coli
total genus 40
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-07-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4lk1A02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4lk1A01
1TWHC 3HKZD 1I6VA 3PO2C 1TWGC 2JA7K 3GTPC 3I4MK 3S1NK 4OIPA 3RZOK 1K83K 4XLNA 2E2JK 3CQZK 4A3LK 3HOZC 4BBSK 3HOVC 4G7HA 3GTOC 3GTOK 4X6AC 4XSZA 5FLMK 4XLPA 1HQMA 3HOYK 4BBRC 4C3IK 4GZYA 3DXJA 4AYBD 3FKIK 2B63C 2NVQC 4A3GC 5C3EC 5C44K 1IW7A 4A3JK 2R7ZK 2JA6C 2NVTK 3I4NC 5IYBC 3HOUC 2NVYC 3RZDK 3S1MK 3GTMC 1YNNA 3S1RC 1I6HK 2NVXK 3HKZL 4C3JC 4A3FC 4A3DK 4A3DC 3HOWK 3M3YC 4JK1A 5C4JC 1SFOC 4MEXA 4A3EK 1SMYA 2JA5K 2VUMK 4BXXK 3EQLA 4QJVA 4C2MK 4C2MC 1Y1WK 5M5WK 5IYCK 2JA7C 3I4MC 3S1NC 3S2HK 3GTKK 3RZOC 1K83C 2E2JC 3CQZC 4A3LC 1ZYRA 4AYBL 1I3QK 4BBSC 1TWFK 5FLMC 4BY7K 2WB1L 4YFXA 3HOYC 3GTGK 4C3IC 5M5YK 4Q4ZA 5TMFA 2WAQL 2JA8K 4A3KK 3FKIC 1I50K 5C44C 2R7ZC 4A3JC 5IYDK 2WB1D 1WCMK 2NVTC 2A69A 4OINA 2WAQD 4MEYA 3RZDC 2YU9C 3S1MC 2YU9K 2R93K 4NOIA 1I6HC 3S1QK 4Y52C 2NVXC 1TWCK 5IP9K 4Y52K 3S15K 4G7ZA 4OIRA 4YFNA 3HOWC 3GTJK 3GTLK 4QJVB 5M3MK 3WODA 4A3EC 2JA5C 5TMCA 2VUMC 4BXXC 1R9TK 3GTQK 1Y1WC 4A3MK 5IYCC 2E2HK 2R92C 5M5XK 4LK0A 1TWAK 4A3IK 4A3IC 3S2HC 2R92K 3GTKC 3M4OK 3M4OC 4A93K 4Y7NK 3PO3K 4BY1K 4BY1C 4C3HK 1I3QC 4A3CK 5D4DA 4LK1A 1TWFC 2CW0A 4G7OA 1Y1VK 4BY7C 3GTGC 4A3BK 4MQ9A 3S17K 2JA8C 4Q5SA 4A3KC 3S14K 1I50C 3K7AK 2E2IK 2PA8D 4KN4A 2Y0SD 1WCMC 4YG2A 5IYDC 4KMUA 3HOXK 4ZH4A 3H0GK 3H0GC 2R93C 3S1QC 3S2DK 5IP9C 2A6EA 1TWCC 1TWHK 2A6HA 1BDFA 4QIWD 4LLGA 3S15C 2O5JA 1TWGK 3GTPK 3PO2K 2PMZL 3GTJC 3H3VL 3GTQC 1R9TC 3S16K 3S16C 3HOZK 4A3MC 3HOVK 5C4XK 2E2HC 3GTLC 5C4XC 4X6AK 1TWAC 4A93C 2PMZD 3H3VD 4KN7A 2A68A 1XPPA 4BBRK 4Y7NC 3PO3C 4LJZA 5FJ8K 4A3CC 4C3HC 4OIQA 2B63K 2NVQK 1Y1VC 5C3EK 2PA8L 4A3GK 2Y0SL 2JA6K 4A3BC 5IP7C 2PPBA 5IP7K 5M3FK 3I4NK 3S17C 5IYBK 3HOUK 2NVYK 4XSXA 3S14C 3GTMK 3S1RK 3K7AC 2E2IC 4C3JK 4A3FK 4QIWL 3M3YK 1YNJA 5C4JK 1SFOK 3HOXC 4OIOA 4YFKA 2BE5A 2O5IA 3S2DC
chains in the Genus database with same CATH superfamily
5JFEA 1WIHA 1USOA 1TWHA 1ZXOA 1I6VA 1TWGA 3GTPC 4XLNA 3HOZC 4XSZA 5FLMK 2D6FC 2GAGC 4C3IK 1FEUA 4WFAS 1ZVUA 3DXJA 3FKIK 2B63C 3LAPA 3GEIA 5IYBC 2NVYA 1PJ7A 3GTMC 1YNNA 2NVXK 1JVIA 5L46A 4A3DC 3HOWK 5C4JC 1SFOC 5TJ3A 1DCHA 4BXXK 1F93A 3TFHA 5M5WK 1O27A 2JA7A 2L5NA 4LR2A 3GTOA 5FLMC 3HXAA 2WB1L 4YFXA 2KWAA 4C3IC 4WILA 4Q4ZA 5TMFA 2JA8K 3FKIC 4BLAA 3OREA 3MMLB 2YU9C 4KM9A 4BKWA 2NVXC 4G7ZA 4OIRA 4YFNA 3HOWC 3AQOA 2GAHC 3GTJK 4QJVB 4WJ3M 3WODA 4BXXC 1O25A 5TMCA 3GTQK 1Y1WA 2RGRA 3GTLK 2FQTA 4A3IC 3M4OC 1VRQC 3TFJA 3PO3K 4A3CK 5D4DA 1B4BA 3S17K 2JA8C 4KMHA 2E2IK 3L4KA 2Y0SD 3G4CA 3HOXK 3H0GK 2R93A 4GFQA 3S2DK 1TWCA 2A6HA 4GTAA 1BJTA 4RMFA 5IOQA 1EFWA 2PMZL 3GTJC 5JVGS 3SZYA 3GTQC 3S16C 3GTLC 4X6AK 1TWAA 1XPPA 2ZJRS 3AH5A 3PO3C 2KXYA 3GEEA 4A3CC 1RU0A 1I3QA 5IORA 3VA7A 1BGWA 2NVQK 4A3GK 1Y1VA 5C3EK 1O2AA 2Y0SL 3BP8C 3AD9C 3I4NK 3S17C 4KAWX 3S1RK 1XXBA 2E2IC 4A3FK 3Q3QA 3M3YK 2PHCB 3A8JA 3HOXC 4OIOA 2CFAA 3S2DC 3HKZD 3I4MK 3S1NK 3GTPA 1WOOA 3ADAC 4X6AC 4U67S 1XZPA 1HQMA 4AYBD 4DDQA 2NVQC 4A3GC 5C3EC 2R7ZK 1IW7A 3N3YA 3ERED 4A3JK 2XCOA 4GTLA 3I4NC 3GTMA 3S1RC 3HKZL 4A3FC 4A3DK 3G4AA 4BLBA 3M3YC 4IOAS 4JK1A 2V6SA 1SFOA 1SMYA 1IBAA 5E68A 2Y3PA 4WFBS 3I4MC 5DM7S 3S1NC 1JQWA 1VLOA 3GTKK 1JOEA 3AQPA 4AYBL 1TWFK 4GT9A 5HQHA 1O26A 3GTGK 1J6VA 5M5YK 2WAQL 1WQFA 3S0XA 1USMA 3FKIA 1I50K 2R7ZC 2XCQA 4A3JC 5IYDK 2WB1D 1WCMK 1XXAA 4FZBA 3V4GA 2JA6A 4OINA 4KASA 2YU9K 4KATA 1B4AA 5IP9K 2NVXA 3PIOS 4G0UA 1R9TK 4XCHA 3A8KA 1DCPA 1X31C 2R92C 2E2HK 4A3IK 3GTKC 3M4OK 1C0AA 4Y7NK 4KC6A 4J3NA 4P9SA 4BY1C 4KARA 1TWFC 4WCES 4G7OA 3GTGC 3BP3A 1XXCA 3S14K 1I50C 3TTGA 4KN4A 5IYDC 1WCMC 2ZFZA 3PIPS 4KMAA 4ZH4A 5IP9C 4KMDA 2GSUA 1WQHA 3GTQA 1R9TC 3S16K 3HOVK 3T02A 2E2HC 5C4XC 1VJEA 3OPFA 3GTLA 1EH1A 1WSRA 2PMZD 4KN7A 2A68A 4BBRK 4Y7NC 4WJ4A 2P5MA 3TFIA 3N0CA 3HOUK 3LYWA 3S14C 1GE9A 2E2IA 2XCRB 3FOEA 1EQRA 3T00A 1YNJA 4LQYA 1IQ0A 1F7UA 3H0GA 2W7VA 4KB4A 1IE0A 2BE5A 2O5IA 4AH6A 4OIPA 3RZOK 1K83K 2E2JK 3CQZK 1V5VA 1J98A 2KPUA 1O2FB 3HOVC 4G7HA 3GTOC 4BBSK 1ISEA 4BBRC 4GZYA 4WFNS 1WSVA 4G0VA 1YX2A 2FQOA 3HOUC 3S1MK 3IPJA 5IOTA 4MEXA 2CFAB 1EI6A 2JA5K 2VUMK 4GTDA 4C2MC 3CF5S 5IYCK 5HL8A 3S2HK 3RZOC 1VGXA 1K83C 2EBBA 2E2JC 3CQZC 3GDZA 1ZYRA 1G51A 4BBSC 1I3QK 1XZPB 4IO9S 3AD7C 4GTBA 4PAAA 3FOFA 2P8TA 4A3KK 2B63A 3AD8C 2R7ZA 1YCLA 3L4JA 1WOSA 3N0BA 2WAQD 3S1MC 3QX3A 4NOIA 4Y52C 1PJ6A 3S15K 4ILDA 3CAGA 4KM8A 5M3MK 2JA5C 2VUMC 2ZUEA 4A3MK 5IYCC 1KQ4A 2R92K 4LK0A 4A93K 3S2HC 3GTKA 1O24A 1XZQA 5CJ9A 4C3HK 1I3QC 4BY1K 2L3UA 2CW0A 1TWFA 4A3BK 3GTGA 4MQ9A 4Q5SA 2JH3A 4A3KC 3K7AK 2PA8D 4YG2A 1WCMA 1EK8A 5EGHA 3JSTA 2YU9A 3LAJA 2A6EA 1TWHK 2GSOA 1BDFA 3S15C 2O5JA 3PO2K 3DLLS 1TWGK 5IOSA 3H3VL 1O28A 3GIRA 3BUEA 1R9TA 4A3MC 5C4XK 2E2HA 1PJ5A 4A93C 5FJ8K 4LJZA 1IS1A 4C3HC 4OIQA 4O2DA 2PA8L 2JA6K 4A3BC 5IP7C 5M3FK 4LOWA 2NVYK 3GSIA 4PABA 3K7AC 2V6UA 4C3JK 3T01A 1WQGA 1O2BA 4YFKA 1L0WA 1TWHC 1ZQ1C 3PO2C 1TWGC 2JA7K 1VH2A 3GTJA 1ZBSA 4A3LK 1O29A 4M1XA 1DD5A 3GTOK 3NUHA 4XLPA 4GTFA 5DM6S 3HOYK 1J6WA 5C44K 2JA6C 2NVTK 1IL2A 3RZDK 2NVYC 4P5AA 1I6HK 4C3JC 2KQ1A 1J6XA 4A3EK 1BS2A 3EQLA 4QJVA 4C2MK 1Y1WK 5HL7S 4KDDA 2JA7C 5CHPA 5JVHS 1K83A 4A3LC 3CQZA 3OEPA 3GEHA 2RH6A 4BY7K 3HOYC 1F7VA 5JVOA 5C44C 2NVTC 2A69A 4MEYA 3RZDC 2ZJPS 4KB2A 2ZUFA 2R93K 1I6HC 3S1QK 1TWCK 4Y52K 3A8IA 1WOPA 3LPXA 3FHZA 4A3EC 2JA5A 4WF9S 2VUMA 1Y1WC 4FM9A 5M5XK 1TWAK 2ZJQS 4IOCS 4G0WA 4LK1A 4GTCA 1Y1VK 4GTEA 4BY7C 4C45A 4KMUA 3H0GC 2R93C 1AB4A 3S1QC 1UV7A 1TWCC 4QIWD 4LLGA 1INNA 3GTPK 2V6TA 3HOZK 2R92A 1TWAC 3H3VD 1XZQB 2GSNA 1DCOA 1HI9A 4P5BA 2B63K 1Y1VC 5IP7K 2PPBA 1F9NA 5EGEA 3SZZA 5IYBK 4XSXA 3GTMK 1I50A 1WORA 4QIWL 5C4JK 1SFOK
chains in the Genus database with same CATH topology
1TWHC 3HKZD 1I6VA 3PO2C 1TWGC 2JA7K 3GTPC 3I4MK 3S1NK 4OIPA 3RZOK 1K83K 4XLNA 2E2JK 3CQZK 4A3LK 3HOZC 4BBSK 3HOVC 4G7HA 3GTOC 3GTOK 4X6AC 4XSZA 5FLMK 4XLPA 1HQMA 3HOYK 4BBRC 4C3IK 4GZYA 3DXJA 4AYBD 3FKIK 2B63C 2NVQC 4A3GC 5C3EC 5C44K 1IW7A 4A3JK 2R7ZK 2JA6C 2NVTK 3I4NC 5IYBC 3HOUC 2NVYC 3RZDK 3S1MK 3GTMC 1YNNA 3S1RC 1I6HK 2NVXK 3HKZL 4C3JC 4A3FC 4A3DK 4A3DC 3HOWK 3M3YC 4JK1A 5C4JC 1SFOC 4MEXA 4A3EK 1SMYA 2JA5K 2VUMK 4BXXK 3EQLA 4QJVA 4C2MK 4C2MC 1Y1WK 5M5WK 5IYCK 2JA7C 3I4MC 3S1NC 3S2HK 3GTKK 3RZOC 1K83C 2E2JC 3CQZC 4A3LC 1ZYRA 4AYBL 1I3QK 4BBSC 1TWFK 5FLMC 4BY7K 2WB1L 4YFXA 3HOYC 3GTGK 4C3IC 5M5YK 4Q4ZA 5TMFA 2WAQL 2JA8K 4A3KK 3FKIC 1I50K 5C44C 2R7ZC 4A3JC 5IYDK 2WB1D 1WCMK 2NVTC 2A69A 4OINA 2WAQD 4MEYA 3RZDC 2YU9C 3S1MC 2YU9K 2R93K 4NOIA 1I6HC 3S1QK 4Y52C 2NVXC 1TWCK 5IP9K 4Y52K 3S15K 4G7ZA 4OIRA 4YFNA 3HOWC 3GTJK 3GTLK 4QJVB 5M3MK 3WODA 4A3EC 2JA5C 5TMCA 2VUMC 4BXXC 1R9TK 3GTQK 1Y1WC 4A3MK 5IYCC 2E2HK 2R92C 5M5XK 4LK0A 1TWAK 4A3IK 4A3IC 3S2HC 2R92K 3GTKC 3M4OK 3M4OC 4A93K 4Y7NK 3PO3K 4BY1K 4BY1C 4C3HK 1I3QC 4A3CK 5D4DA 4LK1A 1TWFC 2CW0A 4G7OA 1Y1VK 4BY7C 3GTGC 4A3BK 4MQ9A 3S17K 2JA8C 4Q5SA 4A3KC 3S14K 1I50C 3K7AK 2E2IK 2PA8D 4KN4A 2Y0SD 1WCMC 4YG2A 5IYDC 4KMUA 3HOXK 4ZH4A 3H0GK 3H0GC 2R93C 3S1QC 3S2DK 5IP9C 2A6EA 1TWCC 1TWHK 2A6HA 1BDFA 4QIWD 4LLGA 3S15C 2O5JA 1TWGK 3GTPK 3PO2K 2PMZL 3GTJC 3H3VL 3GTQC 1R9TC 3S16K 3S16C 3HOZK 4A3MC 3HOVK 5C4XK 2E2HC 3GTLC 5C4XC 4X6AK 1TWAC 4A93C 2PMZD 3H3VD 4KN7A 2A68A 1XPPA 4BBRK 4Y7NC 3PO3C 4LJZA 5FJ8K 4A3CC 4C3HC 4OIQA 2B63K 2NVQK 1Y1VC 5C3EK 2PA8L 4A3GK 2Y0SL 2JA6K 4A3BC 5IP7C 2PPBA 5IP7K 5M3FK 3I4NK 3S17C 5IYBK 3HOUK 2NVYK 4XSXA 3S14C 3GTMK 3S1RK 3K7AC 2E2IC 4C3JK 4A3FK 4QIWL 3M3YK 1YNJA 5C4JK 1SFOK 3HOXC 4OIOA 4YFKA 2BE5A 2O5IA 3S2DC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWH C;  3HKZ D;  1I6V A;  3PO2 C;  1TWG C;  2JA7 K;  3GTP C;  3I4M K;  3S1N K;  4OIP A;  3RZO K;  1K83 K;  4XLN A;  2E2J K;  3CQZ K;  4A3L K;  3HOZ C;  4BBS K;  3HOV C;  4G7H A;  3GTO C;  3GTO K;  4X6A C;  4XSZ A;  5FLM K;  4XLP A;  1HQM A;  3HOY K;  4BBR C;  4C3I K;  4GZY A;  3DXJ A;  4AYB D;  3FKI K;  2B63 C;  2NVQ C;  4A3G C;  5C3E C;  5C44 K;  1IW7 A;  4A3J K;  2R7Z K;  2JA6 C;  2NVT K;  3I4N C;  5IYB C;  3HOU C;  2NVY C;  3RZD K;  3S1M K;  3GTM C;  1YNN A;  3S1R C;  1I6H K;  2NVX K;  3HKZ L;  4C3J C;  4A3F C;  4A3D K;  4A3D C;  3HOW K;  3M3Y C;  4JK1 A;  5C4J C;  1SFO C;  4MEX A;  4A3E K;  1SMY A;  2JA5 K;  2VUM K;  4BXX K;  3EQL A;  4QJV A;  4C2M K;  4C2M C;  1Y1W K;  5M5W K;  5IYC K;  2JA7 C;  3I4M C;  3S1N C;  3S2H K;  3GTK K;  3RZO C;  1K83 C;  2E2J C;  3CQZ C;  4A3L C;  1ZYR A;  4AYB L;  1I3Q K;  4BBS C;  1TWF K;  5FLM C;  4BY7 K;  2WB1 L;  4YFX A;  3HOY C;  3GTG K;  4C3I C;  5M5Y K;  4Q4Z A;  5TMF A;  2WAQ L;  2JA8 K;  4A3K K;  3FKI C;  1I50 K;  5C44 C;  2R7Z C;  4A3J C;  5IYD K;  2WB1 D;  1WCM K;  2NVT C;  2A69 A;  4OIN A;  2WAQ D;  4MEY A;  3RZD C;  2YU9 C;  3S1M C;  2YU9 K;  2R93 K;  4NOI A;  1I6H C;  3S1Q K;  4Y52 C;  2NVX C;  1TWC K;  5IP9 K;  4Y52 K;  3S15 K;  4G7Z A;  4OIR A;  4YFN A;  3HOW C;  3GTJ K;  3GTL K;  4QJV B;  5M3M K;  3WOD A;  4A3E C;  2JA5 C;  5TMC A;  2VUM C;  4BXX C;  1R9T K;  3GTQ K;  1Y1W C;  4A3M K;  5IYC C;  2E2H K;  2R92 C;  5M5X K;  4LK0 A;  1TWA K;  4A3I K;  4A3I C;  3S2H C;  2R92 K;  3GTK C;  3M4O K;  3M4O C;  4A93 K;  4Y7N K;  3PO3 K;  4BY1 K;  4BY1 C;  4C3H K;  1I3Q C;  4A3C K;  5D4D A;  4LK1 A;  1TWF C;  2CW0 A;  4G7O A;  1Y1V K;  4BY7 C;  3GTG C;  4A3B K;  4MQ9 A;  3S17 K;  2JA8 C;  4Q5S A;  4A3K C;  3S14 K;  1I50 C;  3K7A K;  2E2I K;  2PA8 D;  4KN4 A;  2Y0S D;  1WCM C;  4YG2 A;  5IYD C;  4KMU A;  3HOX K;  4ZH4 A;  3H0G K;  3H0G C;  2R93 C;  3S1Q C;  3S2D K;  5IP9 C;  2A6E A;  1TWC C;  1TWH K;  2A6H A;  1BDF A;  4QIW D;  4LLG A;  3S15 C;  2O5J A;  1TWG K;  3GTP K;  3PO2 K;  2PMZ L;  3GTJ C;  3H3V L;  3GTQ C;  1R9T C;  3S16 K;  3S16 C;  3HOZ K;  4A3M C;  3HOV K;  5C4X K;  2E2H C;  3GTL C;  5C4X C;  4X6A K;  1TWA C;  4A93 C;  2PMZ D;  3H3V D;  4KN7 A;  2A68 A;  1XPP A;  4BBR K;  4Y7N C;  3PO3 C;  4LJZ A;  5FJ8 K;  4A3C C;  4C3H C;  4OIQ A;  2B63 K;  2NVQ K;  1Y1V C;  5C3E K;  2PA8 L;  4A3G K;  2Y0S L;  2JA6 K;  4A3B C;  5IP7 C;  2PPB A;  5IP7 K;  5M3F K;  3I4N K;  3S17 C;  5IYB K;  3HOU K;  2NVY K;  4XSX A;  3S14 C;  3GTM K;  3S1R K;  3K7A C;  2E2I C;  4C3J K;  4A3F K;  4QIW L;  3M3Y K;  1YNJ A;  5C4J K;  1SFO K;  3HOX C;  4OIO A;  4YFK A;  2BE5 A;  2O5I A;  3S2D C; 
#chains in the Genus database with same CATH topology
 5JFE A;  1WIH A;  1USO A;  1TWH A;  1ZXO A;  1I6V A;  1TWG A;  3GTP C;  4XLN A;  3HOZ C;  4XSZ A;  5FLM K;  2D6F C;  2GAG C;  4C3I K;  1FEU A;  4WFA S;  1ZVU A;  3DXJ A;  3FKI K;  2B63 C;  3LAP A;  3GEI A;  5IYB C;  2NVY A;  1PJ7 A;  3GTM C;  1YNN A;  2NVX K;  1JVI A;  5L46 A;  4A3D C;  3HOW K;  5C4J C;  1SFO C;  5TJ3 A;  1DCH A;  4BXX K;  1F93 A;  3TFH A;  5M5W K;  1O27 A;  2JA7 A;  2L5N A;  4LR2 A;  3GTO A;  5FLM C;  3HXA A;  2WB1 L;  4YFX A;  2KWA A;  4C3I C;  4WIL A;  4Q4Z A;  5TMF A;  2JA8 K;  3FKI C;  4BLA A;  3ORE A;  3MML B;  2YU9 C;  4KM9 A;  4BKW A;  2NVX C;  4G7Z A;  4OIR A;  4YFN A;  3HOW C;  3AQO A;  2GAH C;  3GTJ K;  4QJV B;  4WJ3 M;  3WOD A;  4BXX C;  1O25 A;  5TMC A;  3GTQ K;  1Y1W A;  2RGR A;  3GTL K;  2FQT A;  4A3I C;  3M4O C;  1VRQ C;  3TFJ A;  3PO3 K;  4A3C K;  5D4D A;  1B4B A;  3S17 K;  2JA8 C;  4KMH A;  2E2I K;  3L4K A;  2Y0S D;  3G4C A;  3HOX K;  3H0G K;  2R93 A;  4GFQ A;  3S2D K;  1TWC A;  2A6H A;  4GTA A;  1BJT A;  4RMF A;  5IOQ A;  1EFW A;  2PMZ L;  3GTJ C;  5JVG S;  3SZY A;  3GTQ C;  3S16 C;  3GTL C;  4X6A K;  1TWA A;  1XPP A;  2ZJR S;  3AH5 A;  3PO3 C;  2KXY A;  3GEE A;  4A3C C;  1RU0 A;  1I3Q A;  5IOR A;  3VA7 A;  1BGW A;  2NVQ K;  4A3G K;  1Y1V A;  5C3E K;  1O2A A;  2Y0S L;  3BP8 C;  3AD9 C;  3I4N K;  3S17 C;  4KAW X;  3S1R K;  1XXB A;  2E2I C;  4A3F K;  3Q3Q A;  3M3Y K;  2PHC B;  3A8J A;  3HOX C;  4OIO A;  2CFA A;  3S2D C;  3HKZ D;  3I4M K;  3S1N K;  3GTP A;  1WOO A;  3ADA C;  4X6A C;  4U67 S;  1XZP A;  1HQM A;  4AYB D;  4DDQ A;  2NVQ C;  4A3G C;  5C3E C;  2R7Z K;  1IW7 A;  3N3Y A;  3ERE D;  4A3J K;  2XCO A;  4GTL A;  3I4N C;  3GTM A;  3S1R C;  3HKZ L;  4A3F C;  4A3D K;  3G4A A;  4BLB A;  3M3Y C;  4IOA S;  4JK1 A;  2V6S A;  1SFO A;  1SMY A;  1IBA A;  5E68 A;  2Y3P A;  4WFB S;  3I4M C;  5DM7 S;  3S1N C;  1JQW A;  1VLO A;  3GTK K;  1JOE A;  3AQP A;  4AYB L;  1TWF K;  4GT9 A;  5HQH A;  1O26 A;  3GTG K;  1J6V A;  5M5Y K;  2WAQ L;  1WQF A;  3S0X A;  1USM A;  3FKI A;  1I50 K;  2R7Z C;  2XCQ A;  4A3J C;  5IYD K;  2WB1 D;  1WCM K;  1XXA A;  4FZB A;  3V4G A;  2JA6 A;  4OIN A;  4KAS A;  2YU9 K;  4KAT A;  1B4A A;  5IP9 K;  2NVX A;  3PIO S;  4G0U A;  1R9T K;  4XCH A;  3A8K A;  1DCP A;  1X31 C;  2R92 C;  2E2H K;  4A3I K;  3GTK C;  3M4O K;  1C0A A;  4Y7N K;  4KC6 A;  4J3N A;  4P9S A;  4BY1 C;  4KAR A;  1TWF C;  4WCE S;  4G7O A;  3GTG C;  3BP3 A;  1XXC A;  3S14 K;  1I50 C;  3TTG A;  4KN4 A;  5IYD C;  1WCM C;  2ZFZ A;  3PIP S;  4KMA A;  4ZH4 A;  5IP9 C;  4KMD A;  2GSU A;  1WQH A;  3GTQ A;  1R9T C;  3S16 K;  3HOV K;  3T02 A;  2E2H C;  5C4X C;  1VJE A;  3OPF A;  3GTL A;  1EH1 A;  1WSR A;  2PMZ D;  4KN7 A;  2A68 A;  4BBR K;  4Y7N C;  4WJ4 A;  2P5M A;  3TFI A;  3N0C A;  3HOU K;  3LYW A;  3S14 C;  1GE9 A;  2E2I A;  2XCR B;  3FOE A;  1EQR A;  3T00 A;  1YNJ A;  4LQY A;  1IQ0 A;  1F7U A;  3H0G A;  2W7V A;  4KB4 A;  1IE0 A;  2BE5 A;  2O5I A;  4AH6 A;  4OIP A;  3RZO K;  1K83 K;  2E2J K;  3CQZ K;  1V5V A;  1J98 A;  2KPU A;  1O2F B;  3HOV C;  4G7H A;  3GTO C;  4BBS K;  1ISE A;  4BBR C;  4GZY A;  4WFN S;  1WSV A;  4G0V A;  1YX2 A;  2FQO A;  3HOU C;  3S1M K;  3IPJ A;  5IOT A;  4MEX A;  2CFA B;  1EI6 A;  2JA5 K;  2VUM K;  4GTD A;  4C2M C;  3CF5 S;  5IYC K;  5HL8 A;  3S2H K;  3RZO C;  1VGX A;  1K83 C;  2EBB A;  2E2J C;  3CQZ C;  3GDZ A;  1ZYR A;  1G51 A;  4BBS C;  1I3Q K;  1XZP B;  4IO9 S;  3AD7 C;  4GTB A;  4PAA A;  3FOF A;  2P8T A;  4A3K K;  2B63 A;  3AD8 C;  2R7Z A;  1YCL A;  3L4J A;  1WOS A;  3N0B A;  2WAQ D;  3S1M C;  3QX3 A;  4NOI A;  4Y52 C;  1PJ6 A;  3S15 K;  4ILD A;  3CAG A;  4KM8 A;  5M3M K;  2JA5 C;  2VUM C;  2ZUE A;  4A3M K;  5IYC C;  1KQ4 A;  2R92 K;  4LK0 A;  4A93 K;  3S2H C;  3GTK A;  1O24 A;  1XZQ A;  5CJ9 A;  4C3H K;  1I3Q C;  4BY1 K;  2L3U A;  2CW0 A;  1TWF A;  4A3B K;  3GTG A;  4MQ9 A;  4Q5S A;  2JH3 A;  4A3K C;  3K7A K;  2PA8 D;  4YG2 A;  1WCM A;  1EK8 A;  5EGH A;  3JST A;  2YU9 A;  3LAJ A;  2A6E A;  1TWH K;  2GSO A;  1BDF A;  3S15 C;  2O5J A;  3PO2 K;  3DLL S;  1TWG K;  5IOS A;  3H3V L;  1O28 A;  3GIR A;  3BUE A;  1R9T A;  4A3M C;  5C4X K;  2E2H A;  1PJ5 A;  4A93 C;  5FJ8 K;  4LJZ A;  1IS1 A;  4C3H C;  4OIQ A;  4O2D A;  2PA8 L;  2JA6 K;  4A3B C;  5IP7 C;  5M3F K;  4LOW A;  2NVY K;  3GSI A;  4PAB A;  3K7A C;  2V6U A;  4C3J K;  3T01 A;  1WQG A;  1O2B A;  4YFK A;  1L0W A;  1TWH C;  1ZQ1 C;  3PO2 C;  1TWG C;  2JA7 K;  1VH2 A;  3GTJ A;  1ZBS A;  4A3L K;  1O29 A;  4M1X A;  1DD5 A;  3GTO K;  3NUH A;  4XLP A;  4GTF A;  5DM6 S;  3HOY K;  1J6W A;  5C44 K;  2JA6 C;  2NVT K;  1IL2 A;  3RZD K;  2NVY C;  4P5A A;  1I6H K;  4C3J C;  2KQ1 A;  1J6X A;  4A3E K;  1BS2 A;  3EQL A;  4QJV A;  4C2M K;  1Y1W K;  5HL7 S;  4KDD A;  2JA7 C;  5CHP A;  5JVH S;  1K83 A;  4A3L C;  3CQZ A;  3OEP A;  3GEH A;  2RH6 A;  4BY7 K;  3HOY C;  1F7V A;  5JVO A;  5C44 C;  2NVT C;  2A69 A;  4MEY A;  3RZD C;  2ZJP S;  4KB2 A;  2ZUF A;  2R93 K;  1I6H C;  3S1Q K;  1TWC K;  4Y52 K;  3A8I A;  1WOP A;  3LPX A;  3FHZ A;  4A3E C;  2JA5 A;  4WF9 S;  2VUM A;  1Y1W C;  4FM9 A;  5M5X K;  1TWA K;  2ZJQ S;  4IOC S;  4G0W A;  4LK1 A;  4GTC A;  1Y1V K;  4GTE A;  4BY7 C;  4C45 A;  4KMU A;  3H0G C;  2R93 C;  1AB4 A;  3S1Q C;  1UV7 A;  1TWC C;  4QIW D;  4LLG A;  1INN A;  3GTP K;  2V6T A;  3HOZ K;  2R92 A;  1TWA C;  3H3V D;  1XZQ B;  2GSN A;  1DCO A;  1HI9 A;  4P5B A;  2B63 K;  1Y1V C;  5IP7 K;  2PPB A;  1F9N A;  5EGE A;  3SZZ A;  5IYB K;  4XSX A;  3GTM K;  1I50 A;  1WOR A;  4QIW L;  5C4J K;  1SFO K; 
#chains in the Genus database with same CATH homology
 1TWH C;  3HKZ D;  1I6V A;  3PO2 C;  1TWG C;  2JA7 K;  3GTP C;  3I4M K;  3S1N K;  4OIP A;  3RZO K;  1K83 K;  4XLN A;  2E2J K;  3CQZ K;  4A3L K;  3HOZ C;  4BBS K;  3HOV C;  4G7H A;  3GTO C;  3GTO K;  4X6A C;  4XSZ A;  5FLM K;  4XLP A;  1HQM A;  3HOY K;  4BBR C;  4C3I K;  4GZY A;  3DXJ A;  4AYB D;  3FKI K;  2B63 C;  2NVQ C;  4A3G C;  5C3E C;  5C44 K;  1IW7 A;  4A3J K;  2R7Z K;  2JA6 C;  2NVT K;  3I4N C;  5IYB C;  3HOU C;  2NVY C;  3RZD K;  3S1M K;  3GTM C;  1YNN A;  3S1R C;  1I6H K;  2NVX K;  3HKZ L;  4C3J C;  4A3F C;  4A3D K;  4A3D C;  3HOW K;  3M3Y C;  4JK1 A;  5C4J C;  1SFO C;  4MEX A;  4A3E K;  1SMY A;  2JA5 K;  2VUM K;  4BXX K;  3EQL A;  4QJV A;  4C2M K;  4C2M C;  1Y1W K;  5M5W K;  5IYC K;  2JA7 C;  3I4M C;  3S1N C;  3S2H K;  3GTK K;  3RZO C;  1K83 C;  2E2J C;  3CQZ C;  4A3L C;  1ZYR A;  4AYB L;  1I3Q K;  4BBS C;  1TWF K;  5FLM C;  4BY7 K;  2WB1 L;  4YFX A;  3HOY C;  3GTG K;  4C3I C;  5M5Y K;  4Q4Z A;  5TMF A;  2WAQ L;  2JA8 K;  4A3K K;  3FKI C;  1I50 K;  5C44 C;  2R7Z C;  4A3J C;  5IYD K;  2WB1 D;  1WCM K;  2NVT C;  2A69 A;  4OIN A;  2WAQ D;  4MEY A;  3RZD C;  2YU9 C;  3S1M C;  2YU9 K;  2R93 K;  4NOI A;  1I6H C;  3S1Q K;  4Y52 C;  2NVX C;  1TWC K;  5IP9 K;  4Y52 K;  3S15 K;  4G7Z A;  4OIR A;  4YFN A;  3HOW C;  3GTJ K;  3GTL K;  4QJV B;  5M3M K;  3WOD A;  4A3E C;  2JA5 C;  5TMC A;  2VUM C;  4BXX C;  1R9T K;  3GTQ K;  1Y1W C;  4A3M K;  5IYC C;  2E2H K;  2R92 C;  5M5X K;  4LK0 A;  1TWA K;  4A3I K;  4A3I C;  3S2H C;  2R92 K;  3GTK C;  3M4O K;  3M4O C;  4A93 K;  4Y7N K;  3PO3 K;  4BY1 K;  4BY1 C;  4C3H K;  1I3Q C;  4A3C K;  5D4D A;  4LK1 A;  1TWF C;  2CW0 A;  4G7O A;  1Y1V K;  4BY7 C;  3GTG C;  4A3B K;  4MQ9 A;  3S17 K;  2JA8 C;  4Q5S A;  4A3K C;  3S14 K;  1I50 C;  3K7A K;  2E2I K;  2PA8 D;  4KN4 A;  2Y0S D;  1WCM C;  4YG2 A;  5IYD C;  4KMU A;  3HOX K;  4ZH4 A;  3H0G K;  3H0G C;  2R93 C;  3S1Q C;  3S2D K;  5IP9 C;  2A6E A;  1TWC C;  1TWH K;  2A6H A;  1BDF A;  4QIW D;  4LLG A;  3S15 C;  2O5J A;  1TWG K;  3GTP K;  3PO2 K;  2PMZ L;  3GTJ C;  3H3V L;  3GTQ C;  1R9T C;  3S16 K;  3S16 C;  3HOZ K;  4A3M C;  3HOV K;  5C4X K;  2E2H C;  3GTL C;  5C4X C;  4X6A K;  1TWA C;  4A93 C;  2PMZ D;  3H3V D;  4KN7 A;  2A68 A;  1XPP A;  4BBR K;  4Y7N C;  3PO3 C;  4LJZ A;  5FJ8 K;  4A3C C;  4C3H C;  4OIQ A;  2B63 K;  2NVQ K;  1Y1V C;  5C3E K;  2PA8 L;  4A3G K;  2Y0S L;  2JA6 K;  4A3B C;  5IP7 C;  2PPB A;  5IP7 K;  5M3F K;  3I4N K;  3S17 C;  5IYB K;  3HOU K;  2NVY K;  4XSX A;  3S14 C;  3GTM K;  3S1R K;  3K7A C;  2E2I C;  4C3J K;  4A3F K;  4QIW L;  3M3Y K;  1YNJ A;  5C4J K;  1SFO K;  3HOX C;  4OIO A;  4YFK A;  2BE5 A;  2O5I A;  3S2D C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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