4LPGF

Crystal structure of human fpps in complex with cl01131
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
342
structure length
341
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
total genus 128
structure length 341
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4lpgF00
5DW7A 3WCHA 3Q2ZA 3RYEA 2RAHA 5B0IA 4KVWA 3KBKA 3AQCB 3P8LA 2AEKA 5B0LA 2E91A 4KQUA 2F92F 4RNQA 4LPHF 3ZCDA 4H5DF 3TFNA 2PS6A 5DGSF 1WMWA 5ILDA 3VJEA 2VF6A 2F89F 3MAVA 2E8WA 3ACWA 2Q9ZA 4P0XA 5JV2F 3N5HF 4RXCA 4JYXA 1V4HA 3KROB 3M9UA 3N46F 4NKFA 4LUUA 3M0GA 3VJDA 1DI1A 4H5CF 3LMDA 4H5EF 4OGUA 3N6KF 1WKZA 1ZW5A 2AZLA 5B0JA 4KFAA 2ONHA 4KVYA 3EFQA 3PH7A 5A0KA 3KRPA 5HN7A 2AETA 2F8ZF 3NPRA 5IMPA 5IK9A 4LZCA 3TS7A 5ILIA 4QPFA 2F94F 2ONGA 4P0VA 1UBVA 3M02A 3P5RA 1JFAA 4NUAA 4E9UA 1HM4A 2ZCQA 3KRAA 4JZBA 2E95A 1YJ4A 4KQSA 3ZL6A 3WEHA 1FPSA 3V66A 2Q80A 3NPKA 3RYWA 4RYPA 3UCAA 5A0IA 2Z4YA 5JV1F 1UBWA 3LOMA 2EWGA 2E8VA 1YYUA 3V1XA 3KRPB 5AFXA 5AELA 4XQSF 3WCMA 5ILYA 3WJOA 3N0FA 2ZY1A 5IL8A 4NG6A 2Z7HA 5IVGA 2E8UA 3WC9A 4LA6A 4JXYA 3TFVA 4EA2A 2J1OA 3Q30A 4HD1A 4RXEA 2FTZA 3VJAA 1YHLA 2AZJA 4NFIF 1N1ZA 3M01A 2J5CA 5ERMA 1N22A 3QQVA 3IPIA 5DGNF 4WK5A 1EZFA 5B00A 3ICZA 3RBMA 3WSAA 1HXGA 4NFJF 3VJ8A 3WCDA 3RMGA 2PS7A 3P41A 1WL2A 4QXSF 4LZ0A 3Q1OA 4KK2A 2OPNA 4JZXA 1YYQA 1WL3A 3S9VA 4DXJA 5IMIA 5EAUA 4KVDA 3TFPA 1YHMA 2H8OA 1UBYA 5JA0F 4LZ3A 3WCEA 3LG5A 3KB9A 2ZCSA 1VG2A 5DJPF 3ACXA 2E90A 2J1PA 3LZ9A 4LFVF 4KKMA 2DH4A 5DJRF 4LXWA 3PYAA 4DI5A 4UMJA 3OYRA 4GP1A 4XQTF 3SDQA 3PDEA 4LIXA 5C05A 2ZCRA 2QISA 3ASXA 2OA6A 2Q58A 3VJBA 3WCFA 3WCAA 1V4IA 2OGDA 3WEGA 5AYPA 1RQJA 3OACA 3ICKA 3WEKA 3SAEA 5DHKA 5EATA 1VG6A 2Z78A 1YQ7A 4DZWA 2PS4A 5IKAA 4KVIA 4XQRF 3WEFA 5H9DA 1V4JA 4GA3A 3P8RA 3ICMA 2E4OA 4LFEA 4PVYF 2I19A 5JV0F 1PS1A 4LTVA 4LA5A 1VG3A 3V1VA 3QKCA 4DHDA 2Z4VA 4ZQ8A 3SDVA 5IL3A 2ZCOA 3NRIA 4MC0A 1HX9A 2O1OA 4LTZA 5DHIA 4Q23A 1N23A 5A0JA 2E8TA 3ICNA 4MC3A 3LJIA 5IM1A 4F62A 3WCIA 4NFKF 3OACB 3CC9A 3IBAA 3N1WF 5I1UA 1JFGA 4LPGF 3CKEA 3Q2QA 1N21A 1YYTA 4EA0A 3BNYA 1V4EA 3LLWA 3LVSA 2Z4ZA 3KRCA 5B0MA 1HM7A 5KSXF 3W7FA 1N20A 3LK5A 2Z50A 5IMNA 3G4FA 2AELA 3AQ0A 5E8LA 2E8XA 4OMHA 5IK6A 4PVXF 2Z4XA 3WSBA 3WCGA 3N5JF 4E1EA 1V4KA 4L2XF 4LLSA 1YV5A 3ZOUA 3N1VF 5ILJA 4KQ5A 3N3LF 4FP4A 3WCCA 5HNAA 3PKOA 5HN9A 3WEIA 1YYRA 2E92A 4P0WA 2ZEVA 3KRFB 1RQIA 2F9KF 3KRCB 1KIZA 5EROA 1HXAA 5CG5A 4NKEA 2AZKA 3ZMCA 4LFGA 5ER8A 5B02A 3N45F 1N1BA 3WCLA 2F7MF 3P5PA 3OABB 3LGZB 4RXDA 5HN8A 3SDRA 1WL1A 4KWDA 3LGKA 4KUXA 3WCBA 5IKHA 3ACYA 1WL0A 4GAXA 5DIQF 5B03A 3ID0A 4KPDA 2Z52A 1VG7A 4LOBA 4EA1A 3SDUA 3DYGA 3N0GA 2Z7IA 2F8CF 3LSNA 5ILHA 2OPMA 3VJCA 5JUZF 2ZEUA 5ILZA 3EZ3A 3N49F 5DZ2A 3MZVA 5ERNA 4N1ZF 2P1CA 4N9UA 1YHKA 4DEMF 4F6XA 3DYFA 3VJ9A 5B0KA 5CG6A 3WEJA 4MC8A 3APZA 3ZMBA 3LEEA 5DGMF 2FORA 4KPJA 3LDWA 3BNXA 4JVJF 4JXNA 3B7LA 4RXAA 4E9ZA 5IN8A 3WCJA 4GP2A 5DJVF 5B01A 1KIYA 4FJQA 2PS5A 2PS8A 3WJKA 3PYBA 3KRFA 1VG4A 4K10A 4OKMA 4LLTA 3ADZA 3SDTA 1WY0A 5E8HA 5EASA 3AQBB 1N24A 1RTRA 3CP6A 1HXCA 5IK0A 3WJNA 3OABA 3NF2A 3EGTA 4DWGA 3KROA 2E94A 3G4DA 2Q9YA 3N3DA 1DGPA 1YYSA 3AE0A 3M00A 5E8KA 4OMGA 4DWBA 3KRAB 3TC1A 2E93A 2Z4WA 3WE9A 5AHUB 5ILKA 4OKZA 1UBXA 3S4JA 4F6VA 3DYHA
chains in the Genus database with same CATH superfamily
5DW7A 3WCHA 3Q2ZA 3RYEA 2RAHA 5B0IA 4KVWA 3KBKA 3AQCB 3P8LA 2AEKA 5B0LA 2E91A 4KQUA 2F92F 4RNQA 4LPHF 3ZCDA 4H5DF 3TFNA 2PS6A 5DGSF 1WMWA 5ILDA 3VJEA 2VF6A 2F89F 3MAVA 2E8WA 3ACWA 2Q9ZA 4P0XA 5JV2F 3N5HF 4RXCA 4JYXA 1V4HA 3KROB 3M9UA 3N46F 4NKFA 4LUUA 3M0GA 3VJDA 1DI1A 4H5CF 3LMDA 4H5EF 4OGUA 3N6KF 1WKZA 1ZW5A 2AZLA 5B0JA 4KFAA 2ONHA 4KVYA 3EFQA 3PH7A 5A0KA 3KRPA 5HN7A 2AETA 2F8ZF 3NPRA 5IMPA 5IK9A 4LZCA 3TS7A 5ILIA 4QPFA 2F94F 2ONGA 4P0VA 1UBVA 3M02A 3P5RA 1JFAA 4NUAA 4E9UA 1HM4A 2ZCQA 3KRAA 4JZBA 2E95A 1YJ4A 4KQSA 3ZL6A 3WEHA 1FPSA 3V66A 2Q80A 3NPKA 3RYWA 4RYPA 3UCAA 5A0IA 2Z4YA 5JV1F 1UBWA 3LOMA 2EWGA 2E8VA 1YYUA 3V1XA 3KRPB 5AFXA 5AELA 4XQSF 3WCMA 5ILYA 3WJOA 3N0FA 2ZY1A 5IL8A 4NG6A 2Z7HA 5IVGA 2E8UA 3WC9A 4LA6A 4JXYA 3TFVA 4EA2A 2J1OA 3Q30A 4HD1A 4RXEA 2FTZA 3VJAA 1YHLA 2AZJA 4NFIF 1N1ZA 3M01A 2J5CA 5ERMA 1N22A 3QQVA 3IPIA 5DGNF 4WK5A 1EZFA 5B00A 3ICZA 3RBMA 3WSAA 1HXGA 4NFJF 3VJ8A 3WCDA 3RMGA 2PS7A 3P41A 1WL2A 4QXSF 4LZ0A 3Q1OA 4KK2A 2OPNA 4JZXA 1YYQA 1WL3A 3S9VA 4DXJA 5IMIA 5EAUA 4KVDA 3TFPA 1YHMA 2H8OA 1UBYA 5JA0F 4LZ3A 3WCEA 3LG5A 3KB9A 2ZCSA 1VG2A 5DJPF 3ACXA 2E90A 2J1PA 3LZ9A 4LFVF 4KKMA 2DH4A 5DJRF 4LXWA 3PYAA 4DI5A 4UMJA 3OYRA 4GP1A 4XQTF 3SDQA 3PDEA 4LIXA 5C05A 2ZCRA 2QISA 3ASXA 2OA6A 2Q58A 3VJBA 3WCFA 3WCAA 1V4IA 2OGDA 3WEGA 5AYPA 1RQJA 3OACA 3ICKA 3WEKA 3SAEA 5DHKA 5EATA 1VG6A 2Z78A 1YQ7A 4DZWA 2PS4A 5IKAA 4KVIA 4XQRF 3WEFA 5H9DA 1V4JA 4GA3A 3P8RA 3ICMA 2E4OA 4LFEA 4PVYF 2I19A 5JV0F 1PS1A 4LTVA 4LA5A 1VG3A 3V1VA 3QKCA 4DHDA 2Z4VA 4ZQ8A 3SDVA 5IL3A 2ZCOA 3NRIA 4MC0A 1HX9A 2O1OA 4LTZA 5DHIA 4Q23A 1N23A 5A0JA 2E8TA 3ICNA 4MC3A 3LJIA 5IM1A 4F62A 3WCIA 4NFKF 3OACB 3CC9A 3IBAA 3N1WF 5I1UA 1JFGA 4LPGF 3CKEA 3Q2QA 1N21A 1YYTA 4EA0A 3BNYA 1V4EA 3LLWA 3LVSA 2Z4ZA 3KRCA 5B0MA 1HM7A 5KSXF 3W7FA 1N20A 3LK5A 2Z50A 5IMNA 3G4FA 2AELA 3AQ0A 5E8LA 2E8XA 4OMHA 5IK6A 4PVXF 2Z4XA 3WSBA 3WCGA 3N5JF 4E1EA 1V4KA 4L2XF 4LLSA 1YV5A 3ZOUA 3N1VF 5ILJA 4KQ5A 3N3LF 4FP4A 3WCCA 5HNAA 3PKOA 5HN9A 3WEIA 1YYRA 2E92A 4P0WA 2ZEVA 3KRFB 1RQIA 2F9KF 3KRCB 1KIZA 5EROA 1HXAA 5CG5A 4NKEA 2AZKA 3ZMCA 4LFGA 5ER8A 5B02A 3N45F 1N1BA 3WCLA 2F7MF 3P5PA 3OABB 3LGZB 4RXDA 5HN8A 3SDRA 1WL1A 4KWDA 3LGKA 4KUXA 3WCBA 5IKHA 3ACYA 1WL0A 4GAXA 5DIQF 5B03A 3ID0A 4KPDA 2Z52A 1VG7A 4LOBA 4EA1A 3SDUA 3DYGA 3N0GA 2Z7IA 2F8CF 3LSNA 5ILHA 2OPMA 3VJCA 5JUZF 2ZEUA 5ILZA 3EZ3A 3N49F 5DZ2A 3MZVA 5ERNA 4N1ZF 2P1CA 4N9UA 1YHKA 4DEMF 4F6XA 3DYFA 3VJ9A 5B0KA 5CG6A 3WEJA 4MC8A 3APZA 3ZMBA 3LEEA 5DGMF 2FORA 4KPJA 3LDWA 3BNXA 4JVJF 4JXNA 3B7LA 4RXAA 4E9ZA 5IN8A 3WCJA 4GP2A 5DJVF 5B01A 1KIYA 4FJQA 2PS5A 2PS8A 3WJKA 3PYBA 3KRFA 1VG4A 4K10A 4OKMA 4LLTA 3ADZA 3SDTA 1WY0A 5E8HA 5EASA 3AQBB 1N24A 1RTRA 3CP6A 1HXCA 5IK0A 3WJNA 3OABA 3NF2A 3EGTA 4DWGA 3KROA 2E94A 3G4DA 2Q9YA 3N3DA 1DGPA 1YYSA 3AE0A 3M00A 5E8KA 4OMGA 4DWBA 3KRAB 3TC1A 2E93A 2Z4WA 3WE9A 5AHUB 5ILKA 4OKZA 1UBXA 3S4JA 4F6VA 3DYHA
chains in the Genus database with same CATH topology
5DW7A 3WCHA 3Q2ZA 3RYEA 2RAHA 5B0IA 4KVWA 3KBKA 3AQCB 3P8LA 2AEKA 5B0LA 2E91A 4KQUA 2F92F 4RNQA 4LPHF 3ZCDA 4H5DF 3TFNA 2PS6A 5DGSF 1WMWA 5ILDA 3VJEA 2VF6A 2F89F 3MAVA 2E8WA 3ACWA 2Q9ZA 4P0XA 5JV2F 3N5HF 4RXCA 4JYXA 1V4HA 3KROB 3M9UA 3N46F 4NKFA 4LUUA 3M0GA 3VJDA 1DI1A 4H5CF 3LMDA 4H5EF 4OGUA 3N6KF 1WKZA 1ZW5A 2AZLA 5B0JA 4KFAA 2ONHA 4KVYA 3EFQA 3PH7A 5A0KA 3KRPA 5HN7A 2AETA 2F8ZF 3NPRA 5IMPA 5IK9A 4LZCA 3TS7A 5ILIA 4QPFA 2F94F 2ONGA 4P0VA 1UBVA 3M02A 3P5RA 1JFAA 4NUAA 4E9UA 1HM4A 2ZCQA 3KRAA 4JZBA 2E95A 1YJ4A 4KQSA 3ZL6A 3WEHA 1FPSA 3V66A 2Q80A 3NPKA 3RYWA 4RYPA 3UCAA 5A0IA 2Z4YA 5JV1F 1UBWA 3LOMA 2EWGA 2E8VA 1YYUA 3V1XA 3KRPB 5AFXA 5AELA 4XQSF 3WCMA 5ILYA 3WJOA 3N0FA 2ZY1A 5IL8A 4NG6A 2Z7HA 5IVGA 2E8UA 3WC9A 4LA6A 4JXYA 3TFVA 4EA2A 2J1OA 3Q30A 4HD1A 4RXEA 2FTZA 3VJAA 1YHLA 2AZJA 4NFIF 1N1ZA 3M01A 2J5CA 5ERMA 1N22A 3QQVA 3IPIA 5DGNF 4WK5A 1EZFA 5B00A 3ICZA 3RBMA 3WSAA 1HXGA 4NFJF 3VJ8A 3WCDA 3RMGA 2PS7A 3P41A 1WL2A 4QXSF 4LZ0A 3Q1OA 4KK2A 2OPNA 4JZXA 1YYQA 1WL3A 3S9VA 4DXJA 5IMIA 5EAUA 4KVDA 3TFPA 1YHMA 2H8OA 1UBYA 5JA0F 4LZ3A 3WCEA 3LG5A 3KB9A 2ZCSA 1VG2A 5DJPF 3ACXA 2E90A 2J1PA 3LZ9A 4LFVF 4KKMA 2DH4A 5DJRF 4LXWA 3PYAA 4DI5A 4UMJA 3OYRA 4GP1A 4XQTF 3SDQA 3PDEA 4LIXA 5C05A 2ZCRA 2QISA 3ASXA 2OA6A 2Q58A 3VJBA 3WCFA 3WCAA 1V4IA 2OGDA 3WEGA 5AYPA 1RQJA 3OACA 3ICKA 3WEKA 3SAEA 5DHKA 5EATA 1VG6A 2Z78A 1YQ7A 4DZWA 2PS4A 5IKAA 4KVIA 4XQRF 3WEFA 5H9DA 1V4JA 4GA3A 3P8RA 3ICMA 2E4OA 4LFEA 4PVYF 2I19A 5JV0F 1PS1A 4LTVA 4LA5A 1VG3A 3V1VA 3QKCA 4DHDA 2Z4VA 4ZQ8A 3SDVA 5IL3A 2ZCOA 3NRIA 4MC0A 1HX9A 2O1OA 4LTZA 5DHIA 4Q23A 1N23A 5A0JA 2E8TA 3ICNA 4MC3A 3LJIA 5IM1A 4F62A 3WCIA 4NFKF 3OACB 3CC9A 3IBAA 3N1WF 5I1UA 1JFGA 4LPGF 3CKEA 3Q2QA 1N21A 1YYTA 4EA0A 3BNYA 1V4EA 3LLWA 3LVSA 2Z4ZA 3KRCA 5B0MA 1HM7A 5KSXF 3W7FA 1N20A 3LK5A 2Z50A 5IMNA 3G4FA 2AELA 3AQ0A 5E8LA 2E8XA 4OMHA 5IK6A 4PVXF 2Z4XA 3WSBA 3WCGA 3N5JF 4E1EA 1V4KA 4L2XF 4LLSA 1YV5A 3ZOUA 3N1VF 5ILJA 4KQ5A 3N3LF 4FP4A 3WCCA 5HNAA 3PKOA 5HN9A 3WEIA 1YYRA 2E92A 4P0WA 2ZEVA 3KRFB 1RQIA 2F9KF 3KRCB 1KIZA 5EROA 1HXAA 5CG5A 4NKEA 2AZKA 3ZMCA 4LFGA 5ER8A 5B02A 3N45F 1N1BA 3WCLA 2F7MF 3P5PA 3OABB 3LGZB 4RXDA 5HN8A 3SDRA 1WL1A 4KWDA 3LGKA 4KUXA 3WCBA 5IKHA 3ACYA 1WL0A 4GAXA 5DIQF 5B03A 3ID0A 4KPDA 2Z52A 1VG7A 4LOBA 4EA1A 3SDUA 3DYGA 3N0GA 2Z7IA 2F8CF 3LSNA 5ILHA 2OPMA 3VJCA 5JUZF 2ZEUA 5ILZA 3EZ3A 3N49F 5DZ2A 3MZVA 5ERNA 4N1ZF 2P1CA 4N9UA 1YHKA 4DEMF 4F6XA 3DYFA 3VJ9A 5B0KA 5CG6A 3WEJA 4MC8A 3APZA 3ZMBA 3LEEA 5DGMF 2FORA 4KPJA 3LDWA 3BNXA 4JVJF 4JXNA 3B7LA 4RXAA 4E9ZA 5IN8A 3WCJA 4GP2A 5DJVF 5B01A 1KIYA 4FJQA 2PS5A 2PS8A 3WJKA 3PYBA 3KRFA 1VG4A 4K10A 4OKMA 4LLTA 3ADZA 3SDTA 1WY0A 5E8HA 5EASA 3AQBB 1N24A 1RTRA 3CP6A 1HXCA 5IK0A 3WJNA 3OABA 3NF2A 3EGTA 4DWGA 3KROA 2E94A 3G4DA 2Q9YA 3N3DA 1DGPA 1YYSA 3AE0A 3M00A 5E8KA 4OMGA 4DWBA 3KRAB 3TC1A 2E93A 2Z4WA 3WE9A 5AHUB 5ILKA 4OKZA 1UBXA 3S4JA 4F6VA 3DYHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DW7 A;  3WCH A;  3Q2Z A;  3RYE A;  2RAH A;  5B0I A;  4KVW A;  3KBK A;  3AQC B;  3P8L A;  2AEK A;  5B0L A;  2E91 A;  4KQU A;  2F92 F;  4RNQ A;  4LPH F;  3ZCD A;  4H5D F;  3TFN A;  2PS6 A;  5DGS F;  1WMW A;  5ILD A;  3VJE A;  2VF6 A;  2F89 F;  3MAV A;  2E8W A;  3ACW A;  2Q9Z A;  4P0X A;  5JV2 F;  3N5H F;  4RXC A;  4JYX A;  1V4H A;  3KRO B;  3M9U A;  3N46 F;  4NKF A;  4LUU A;  3M0G A;  3VJD A;  1DI1 A;  4H5C F;  3LMD A;  4H5E F;  4OGU A;  3N6K F;  1WKZ A;  1ZW5 A;  2AZL A;  5B0J A;  4KFA A;  2ONH A;  4KVY A;  3EFQ A;  3PH7 A;  5A0K A;  3KRP A;  5HN7 A;  2AET A;  2F8Z F;  3NPR A;  5IMP A;  5IK9 A;  4LZC A;  3TS7 A;  5ILI A;  4QPF A;  2F94 F;  2ONG A;  4P0V A;  1UBV A;  3M02 A;  3P5R A;  1JFA A;  4NUA A;  4E9U A;  1HM4 A;  2ZCQ A;  3KRA A;  4JZB A;  2E95 A;  1YJ4 A;  4KQS A;  3ZL6 A;  3WEH A;  1FPS A;  3V66 A;  2Q80 A;  3NPK A;  3RYW A;  4RYP A;  3UCA A;  5A0I A;  2Z4Y A;  5JV1 F;  1UBW A;  3LOM A;  2EWG A;  2E8V A;  1YYU A;  3V1X A;  3KRP B;  5AFX A;  5AEL A;  4XQS F;  3WCM A;  5ILY A;  3WJO A;  3N0F A;  2ZY1 A;  5IL8 A;  4NG6 A;  2Z7H A;  5IVG A;  2E8U A;  3WC9 A;  4LA6 A;  4JXY A;  3TFV A;  4EA2 A;  2J1O A;  3Q30 A;  4HD1 A;  4RXE A;  2FTZ A;  3VJA A;  1YHL A;  2AZJ A;  4NFI F;  1N1Z A;  3M01 A;  2J5C A;  5ERM A;  1N22 A;  3QQV A;  3IPI A;  5DGN F;  4WK5 A;  1EZF A;  5B00 A;  3ICZ A;  3RBM A;  3WSA A;  1HXG A;  4NFJ F;  3VJ8 A;  3WCD A;  3RMG A;  2PS7 A;  3P41 A;  1WL2 A;  4QXS F;  4LZ0 A;  3Q1O A;  4KK2 A;  2OPN A;  4JZX A;  1YYQ A;  1WL3 A;  3S9V A;  4DXJ A;  5IMI A;  5EAU A;  4KVD A;  3TFP A;  1YHM A;  2H8O A;  1UBY A;  5JA0 F;  4LZ3 A;  3WCE A;  3LG5 A;  3KB9 A;  2ZCS A;  1VG2 A;  5DJP F;  3ACX A;  2E90 A;  2J1P A;  3LZ9 A;  4LFV F;  4KKM A;  2DH4 A;  5DJR F;  4LXW A;  3PYA A;  4DI5 A;  4UMJ A;  3OYR A;  4GP1 A;  4XQT F;  3SDQ A;  3PDE A;  4LIX A;  5C05 A;  2ZCR A;  2QIS A;  3ASX A;  2OA6 A;  2Q58 A;  3VJB A;  3WCF A;  3WCA A;  1V4I A;  2OGD A;  3WEG A;  5AYP A;  1RQJ A;  3OAC A;  3ICK A;  3WEK A;  3SAE A;  5DHK A;  5EAT A;  1VG6 A;  2Z78 A;  1YQ7 A;  4DZW A;  2PS4 A;  5IKA A;  4KVI A;  4XQR F;  3WEF A;  5H9D A;  1V4J A;  4GA3 A;  3P8R A;  3ICM A;  2E4O A;  4LFE A;  4PVY F;  2I19 A;  5JV0 F;  1PS1 A;  4LTV A;  4LA5 A;  1VG3 A;  3V1V A;  3QKC A;  4DHD A;  2Z4V A;  4ZQ8 A;  3SDV A;  5IL3 A;  2ZCO A;  3NRI A;  4MC0 A;  1HX9 A;  2O1O A;  4LTZ A;  5DHI A;  4Q23 A;  1N23 A;  5A0J A;  2E8T A;  3ICN A;  4MC3 A;  3LJI A;  5IM1 A;  4F62 A;  3WCI A;  4NFK F;  3OAC B;  3CC9 A;  3IBA A;  3N1W F;  5I1U A;  1JFG A;  4LPG F;  3CKE A;  3Q2Q A;  1N21 A;  1YYT A;  4EA0 A;  3BNY A;  1V4E A;  3LLW A;  3LVS A;  2Z4Z A;  3KRC A;  5B0M A;  1HM7 A;  5KSX F;  3W7F A;  1N20 A;  3LK5 A;  2Z50 A;  5IMN A;  3G4F A;  2AEL A;  3AQ0 A;  5E8L A;  2E8X A;  4OMH A;  5IK6 A;  4PVX F;  2Z4X A;  3WSB A;  3WCG A;  3N5J F;  4E1E A;  1V4K A;  4L2X F;  4LLS A;  1YV5 A;  3ZOU A;  3N1V F;  5ILJ A;  4KQ5 A;  3N3L F;  4FP4 A;  3WCC A;  5HNA A;  3PKO A;  5HN9 A;  3WEI A;  1YYR A;  2E92 A;  4P0W A;  2ZEV A;  3KRF B;  1RQI A;  2F9K F;  3KRC B;  1KIZ A;  5ERO A;  1HXA A;  5CG5 A;  4NKE A;  2AZK A;  3ZMC A;  4LFG A;  5ER8 A;  5B02 A;  3N45 F;  1N1B A;  3WCL A;  2F7M F;  3P5P A;  3OAB B;  3LGZ B;  4RXD A;  5HN8 A;  3SDR A;  1WL1 A;  4KWD A;  3LGK A;  4KUX A;  3WCB A;  5IKH A;  3ACY A;  1WL0 A;  4GAX A;  5DIQ F;  5B03 A;  3ID0 A;  4KPD A;  2Z52 A;  1VG7 A;  4LOB A;  4EA1 A;  3SDU A;  3DYG A;  3N0G A;  2Z7I A;  2F8C F;  3LSN A;  5ILH A;  2OPM A;  3VJC A;  5JUZ F;  2ZEU A;  5ILZ A;  3EZ3 A;  3N49 F;  5DZ2 A;  3MZV A;  5ERN A;  4N1Z F;  2P1C A;  4N9U A;  1YHK A;  4DEM F;  4F6X A;  3DYF A;  3VJ9 A;  5B0K A;  5CG6 A;  3WEJ A;  4MC8 A;  3APZ A;  3ZMB A;  3LEE A;  5DGM F;  2FOR A;  4KPJ A;  3LDW A;  3BNX A;  4JVJ F;  4JXN A;  3B7L A;  4RXA A;  4E9Z A;  5IN8 A;  3WCJ A;  4GP2 A;  5DJV F;  5B01 A;  1KIY A;  4FJQ A;  2PS5 A;  2PS8 A;  3WJK A;  3PYB A;  3KRF A;  1VG4 A;  4K10 A;  4OKM A;  4LLT A;  3ADZ A;  3SDT A;  1WY0 A;  5E8H A;  5EAS A;  3AQB B;  1N24 A;  1RTR A;  3CP6 A;  1HXC A;  5IK0 A;  3WJN A;  3OAB A;  3NF2 A;  3EGT A;  4DWG A;  3KRO A;  2E94 A;  3G4D A;  2Q9Y A;  3N3D A;  1DGP A;  1YYS A;  3AE0 A;  3M00 A;  5E8K A;  4OMG A;  4DWB A;  3KRA B;  3TC1 A;  2E93 A;  2Z4W A;  3WE9 A;  5AHU B;  5ILK A;  4OKZ A;  1UBX A;  3S4J A;  4F6V A;  3DYH A; 
#chains in the Genus database with same CATH topology
 5DW7 A;  3WCH A;  3Q2Z A;  3RYE A;  2RAH A;  5B0I A;  4KVW A;  3KBK A;  3AQC B;  3P8L A;  2AEK A;  5B0L A;  2E91 A;  4KQU A;  2F92 F;  4RNQ A;  4LPH F;  3ZCD A;  4H5D F;  3TFN A;  2PS6 A;  5DGS F;  1WMW A;  5ILD A;  3VJE A;  2VF6 A;  2F89 F;  3MAV A;  2E8W A;  3ACW A;  2Q9Z A;  4P0X A;  5JV2 F;  3N5H F;  4RXC A;  4JYX A;  1V4H A;  3KRO B;  3M9U A;  3N46 F;  4NKF A;  4LUU A;  3M0G A;  3VJD A;  1DI1 A;  4H5C F;  3LMD A;  4H5E F;  4OGU A;  3N6K F;  1WKZ A;  1ZW5 A;  2AZL A;  5B0J A;  4KFA A;  2ONH A;  4KVY A;  3EFQ A;  3PH7 A;  5A0K A;  3KRP A;  5HN7 A;  2AET A;  2F8Z F;  3NPR A;  5IMP A;  5IK9 A;  4LZC A;  3TS7 A;  5ILI A;  4QPF A;  2F94 F;  2ONG A;  4P0V A;  1UBV A;  3M02 A;  3P5R A;  1JFA A;  4NUA A;  4E9U A;  1HM4 A;  2ZCQ A;  3KRA A;  4JZB A;  2E95 A;  1YJ4 A;  4KQS A;  3ZL6 A;  3WEH A;  1FPS A;  3V66 A;  2Q80 A;  3NPK A;  3RYW A;  4RYP A;  3UCA A;  5A0I A;  2Z4Y A;  5JV1 F;  1UBW A;  3LOM A;  2EWG A;  2E8V A;  1YYU A;  3V1X A;  3KRP B;  5AFX A;  5AEL A;  4XQS F;  3WCM A;  5ILY A;  3WJO A;  3N0F A;  2ZY1 A;  5IL8 A;  4NG6 A;  2Z7H A;  5IVG A;  2E8U A;  3WC9 A;  4LA6 A;  4JXY A;  3TFV A;  4EA2 A;  2J1O A;  3Q30 A;  4HD1 A;  4RXE A;  2FTZ A;  3VJA A;  1YHL A;  2AZJ A;  4NFI F;  1N1Z A;  3M01 A;  2J5C A;  5ERM A;  1N22 A;  3QQV A;  3IPI A;  5DGN F;  4WK5 A;  1EZF A;  5B00 A;  3ICZ A;  3RBM A;  3WSA A;  1HXG A;  4NFJ F;  3VJ8 A;  3WCD A;  3RMG A;  2PS7 A;  3P41 A;  1WL2 A;  4QXS F;  4LZ0 A;  3Q1O A;  4KK2 A;  2OPN A;  4JZX A;  1YYQ A;  1WL3 A;  3S9V A;  4DXJ A;  5IMI A;  5EAU A;  4KVD A;  3TFP A;  1YHM A;  2H8O A;  1UBY A;  5JA0 F;  4LZ3 A;  3WCE A;  3LG5 A;  3KB9 A;  2ZCS A;  1VG2 A;  5DJP F;  3ACX A;  2E90 A;  2J1P A;  3LZ9 A;  4LFV F;  4KKM A;  2DH4 A;  5DJR F;  4LXW A;  3PYA A;  4DI5 A;  4UMJ A;  3OYR A;  4GP1 A;  4XQT F;  3SDQ A;  3PDE A;  4LIX A;  5C05 A;  2ZCR A;  2QIS A;  3ASX A;  2OA6 A;  2Q58 A;  3VJB A;  3WCF A;  3WCA A;  1V4I A;  2OGD A;  3WEG A;  5AYP A;  1RQJ A;  3OAC A;  3ICK A;  3WEK A;  3SAE A;  5DHK A;  5EAT A;  1VG6 A;  2Z78 A;  1YQ7 A;  4DZW A;  2PS4 A;  5IKA A;  4KVI A;  4XQR F;  3WEF A;  5H9D A;  1V4J A;  4GA3 A;  3P8R A;  3ICM A;  2E4O A;  4LFE A;  4PVY F;  2I19 A;  5JV0 F;  1PS1 A;  4LTV A;  4LA5 A;  1VG3 A;  3V1V A;  3QKC A;  4DHD A;  2Z4V A;  4ZQ8 A;  3SDV A;  5IL3 A;  2ZCO A;  3NRI A;  4MC0 A;  1HX9 A;  2O1O A;  4LTZ A;  5DHI A;  4Q23 A;  1N23 A;  5A0J A;  2E8T A;  3ICN A;  4MC3 A;  3LJI A;  5IM1 A;  4F62 A;  3WCI A;  4NFK F;  3OAC B;  3CC9 A;  3IBA A;  3N1W F;  5I1U A;  1JFG A;  4LPG F;  3CKE A;  3Q2Q A;  1N21 A;  1YYT A;  4EA0 A;  3BNY A;  1V4E A;  3LLW A;  3LVS A;  2Z4Z A;  3KRC A;  5B0M A;  1HM7 A;  5KSX F;  3W7F A;  1N20 A;  3LK5 A;  2Z50 A;  5IMN A;  3G4F A;  2AEL A;  3AQ0 A;  5E8L A;  2E8X A;  4OMH A;  5IK6 A;  4PVX F;  2Z4X A;  3WSB A;  3WCG A;  3N5J F;  4E1E A;  1V4K A;  4L2X F;  4LLS A;  1YV5 A;  3ZOU A;  3N1V F;  5ILJ A;  4KQ5 A;  3N3L F;  4FP4 A;  3WCC A;  5HNA A;  3PKO A;  5HN9 A;  3WEI A;  1YYR A;  2E92 A;  4P0W A;  2ZEV A;  3KRF B;  1RQI A;  2F9K F;  3KRC B;  1KIZ A;  5ERO A;  1HXA A;  5CG5 A;  4NKE A;  2AZK A;  3ZMC A;  4LFG A;  5ER8 A;  5B02 A;  3N45 F;  1N1B A;  3WCL A;  2F7M F;  3P5P A;  3OAB B;  3LGZ B;  4RXD A;  5HN8 A;  3SDR A;  1WL1 A;  4KWD A;  3LGK A;  4KUX A;  3WCB A;  5IKH A;  3ACY A;  1WL0 A;  4GAX A;  5DIQ F;  5B03 A;  3ID0 A;  4KPD A;  2Z52 A;  1VG7 A;  4LOB A;  4EA1 A;  3SDU A;  3DYG A;  3N0G A;  2Z7I A;  2F8C F;  3LSN A;  5ILH A;  2OPM A;  3VJC A;  5JUZ F;  2ZEU A;  5ILZ A;  3EZ3 A;  3N49 F;  5DZ2 A;  3MZV A;  5ERN A;  4N1Z F;  2P1C A;  4N9U A;  1YHK A;  4DEM F;  4F6X A;  3DYF A;  3VJ9 A;  5B0K A;  5CG6 A;  3WEJ A;  4MC8 A;  3APZ A;  3ZMB A;  3LEE A;  5DGM F;  2FOR A;  4KPJ A;  3LDW A;  3BNX A;  4JVJ F;  4JXN A;  3B7L A;  4RXA A;  4E9Z A;  5IN8 A;  3WCJ A;  4GP2 A;  5DJV F;  5B01 A;  1KIY A;  4FJQ A;  2PS5 A;  2PS8 A;  3WJK A;  3PYB A;  3KRF A;  1VG4 A;  4K10 A;  4OKM A;  4LLT A;  3ADZ A;  3SDT A;  1WY0 A;  5E8H A;  5EAS A;  3AQB B;  1N24 A;  1RTR A;  3CP6 A;  1HXC A;  5IK0 A;  3WJN A;  3OAB A;  3NF2 A;  3EGT A;  4DWG A;  3KRO A;  2E94 A;  3G4D A;  2Q9Y A;  3N3D A;  1DGP A;  1YYS A;  3AE0 A;  3M00 A;  5E8K A;  4OMG A;  4DWB A;  3KRA B;  3TC1 A;  2E93 A;  2Z4W A;  3WE9 A;  5AHU B;  5ILK A;  4OKZ A;  1UBX A;  3S4J A;  4F6V A;  3DYH A; 
#chains in the Genus database with same CATH homology
 5DW7 A;  3WCH A;  3Q2Z A;  3RYE A;  2RAH A;  5B0I A;  4KVW A;  3KBK A;  3AQC B;  3P8L A;  2AEK A;  5B0L A;  2E91 A;  4KQU A;  2F92 F;  4RNQ A;  4LPH F;  3ZCD A;  4H5D F;  3TFN A;  2PS6 A;  5DGS F;  1WMW A;  5ILD A;  3VJE A;  2VF6 A;  2F89 F;  3MAV A;  2E8W A;  3ACW A;  2Q9Z A;  4P0X A;  5JV2 F;  3N5H F;  4RXC A;  4JYX A;  1V4H A;  3KRO B;  3M9U A;  3N46 F;  4NKF A;  4LUU A;  3M0G A;  3VJD A;  1DI1 A;  4H5C F;  3LMD A;  4H5E F;  4OGU A;  3N6K F;  1WKZ A;  1ZW5 A;  2AZL A;  5B0J A;  4KFA A;  2ONH A;  4KVY A;  3EFQ A;  3PH7 A;  5A0K A;  3KRP A;  5HN7 A;  2AET A;  2F8Z F;  3NPR A;  5IMP A;  5IK9 A;  4LZC A;  3TS7 A;  5ILI A;  4QPF A;  2F94 F;  2ONG A;  4P0V A;  1UBV A;  3M02 A;  3P5R A;  1JFA A;  4NUA A;  4E9U A;  1HM4 A;  2ZCQ A;  3KRA A;  4JZB A;  2E95 A;  1YJ4 A;  4KQS A;  3ZL6 A;  3WEH A;  1FPS A;  3V66 A;  2Q80 A;  3NPK A;  3RYW A;  4RYP A;  3UCA A;  5A0I A;  2Z4Y A;  5JV1 F;  1UBW A;  3LOM A;  2EWG A;  2E8V A;  1YYU A;  3V1X A;  3KRP B;  5AFX A;  5AEL A;  4XQS F;  3WCM A;  5ILY A;  3WJO A;  3N0F A;  2ZY1 A;  5IL8 A;  4NG6 A;  2Z7H A;  5IVG A;  2E8U A;  3WC9 A;  4LA6 A;  4JXY A;  3TFV A;  4EA2 A;  2J1O A;  3Q30 A;  4HD1 A;  4RXE A;  2FTZ A;  3VJA A;  1YHL A;  2AZJ A;  4NFI F;  1N1Z A;  3M01 A;  2J5C A;  5ERM A;  1N22 A;  3QQV A;  3IPI A;  5DGN F;  4WK5 A;  1EZF A;  5B00 A;  3ICZ A;  3RBM A;  3WSA A;  1HXG A;  4NFJ F;  3VJ8 A;  3WCD A;  3RMG A;  2PS7 A;  3P41 A;  1WL2 A;  4QXS F;  4LZ0 A;  3Q1O A;  4KK2 A;  2OPN A;  4JZX A;  1YYQ A;  1WL3 A;  3S9V A;  4DXJ A;  5IMI A;  5EAU A;  4KVD A;  3TFP A;  1YHM A;  2H8O A;  1UBY A;  5JA0 F;  4LZ3 A;  3WCE A;  3LG5 A;  3KB9 A;  2ZCS A;  1VG2 A;  5DJP F;  3ACX A;  2E90 A;  2J1P A;  3LZ9 A;  4LFV F;  4KKM A;  2DH4 A;  5DJR F;  4LXW A;  3PYA A;  4DI5 A;  4UMJ A;  3OYR A;  4GP1 A;  4XQT F;  3SDQ A;  3PDE A;  4LIX A;  5C05 A;  2ZCR A;  2QIS A;  3ASX A;  2OA6 A;  2Q58 A;  3VJB A;  3WCF A;  3WCA A;  1V4I A;  2OGD A;  3WEG A;  5AYP A;  1RQJ A;  3OAC A;  3ICK A;  3WEK A;  3SAE A;  5DHK A;  5EAT A;  1VG6 A;  2Z78 A;  1YQ7 A;  4DZW A;  2PS4 A;  5IKA A;  4KVI A;  4XQR F;  3WEF A;  5H9D A;  1V4J A;  4GA3 A;  3P8R A;  3ICM A;  2E4O A;  4LFE A;  4PVY F;  2I19 A;  5JV0 F;  1PS1 A;  4LTV A;  4LA5 A;  1VG3 A;  3V1V A;  3QKC A;  4DHD A;  2Z4V A;  4ZQ8 A;  3SDV A;  5IL3 A;  2ZCO A;  3NRI A;  4MC0 A;  1HX9 A;  2O1O A;  4LTZ A;  5DHI A;  4Q23 A;  1N23 A;  5A0J A;  2E8T A;  3ICN A;  4MC3 A;  3LJI A;  5IM1 A;  4F62 A;  3WCI A;  4NFK F;  3OAC B;  3CC9 A;  3IBA A;  3N1W F;  5I1U A;  1JFG A;  4LPG F;  3CKE A;  3Q2Q A;  1N21 A;  1YYT A;  4EA0 A;  3BNY A;  1V4E A;  3LLW A;  3LVS A;  2Z4Z A;  3KRC A;  5B0M A;  1HM7 A;  5KSX F;  3W7F A;  1N20 A;  3LK5 A;  2Z50 A;  5IMN A;  3G4F A;  2AEL A;  3AQ0 A;  5E8L A;  2E8X A;  4OMH A;  5IK6 A;  4PVX F;  2Z4X A;  3WSB A;  3WCG A;  3N5J F;  4E1E A;  1V4K A;  4L2X F;  4LLS A;  1YV5 A;  3ZOU A;  3N1V F;  5ILJ A;  4KQ5 A;  3N3L F;  4FP4 A;  3WCC A;  5HNA A;  3PKO A;  5HN9 A;  3WEI A;  1YYR A;  2E92 A;  4P0W A;  2ZEV A;  3KRF B;  1RQI A;  2F9K F;  3KRC B;  1KIZ A;  5ERO A;  1HXA A;  5CG5 A;  4NKE A;  2AZK A;  3ZMC A;  4LFG A;  5ER8 A;  5B02 A;  3N45 F;  1N1B A;  3WCL A;  2F7M F;  3P5P A;  3OAB B;  3LGZ B;  4RXD A;  5HN8 A;  3SDR A;  1WL1 A;  4KWD A;  3LGK A;  4KUX A;  3WCB A;  5IKH A;  3ACY A;  1WL0 A;  4GAX A;  5DIQ F;  5B03 A;  3ID0 A;  4KPD A;  2Z52 A;  1VG7 A;  4LOB A;  4EA1 A;  3SDU A;  3DYG A;  3N0G A;  2Z7I A;  2F8C F;  3LSN A;  5ILH A;  2OPM A;  3VJC A;  5JUZ F;  2ZEU A;  5ILZ A;  3EZ3 A;  3N49 F;  5DZ2 A;  3MZV A;  5ERN A;  4N1Z F;  2P1C A;  4N9U A;  1YHK A;  4DEM F;  4F6X A;  3DYF A;  3VJ9 A;  5B0K A;  5CG6 A;  3WEJ A;  4MC8 A;  3APZ A;  3ZMB A;  3LEE A;  5DGM F;  2FOR A;  4KPJ A;  3LDW A;  3BNX A;  4JVJ F;  4JXN A;  3B7L A;  4RXA A;  4E9Z A;  5IN8 A;  3WCJ A;  4GP2 A;  5DJV F;  5B01 A;  1KIY A;  4FJQ A;  2PS5 A;  2PS8 A;  3WJK A;  3PYB A;  3KRF A;  1VG4 A;  4K10 A;  4OKM A;  4LLT A;  3ADZ A;  3SDT A;  1WY0 A;  5E8H A;  5EAS A;  3AQB B;  1N24 A;  1RTR A;  3CP6 A;  1HXC A;  5IK0 A;  3WJN A;  3OAB A;  3NF2 A;  3EGT A;  4DWG A;  3KRO A;  2E94 A;  3G4D A;  2Q9Y A;  3N3D A;  1DGP A;  1YYS A;  3AE0 A;  3M00 A;  5E8K A;  4OMG A;  4DWB A;  3KRA B;  3TC1 A;  2E93 A;  2Z4W A;  3WE9 A;  5AHU B;  5ILK A;  4OKZ A;  1UBX A;  3S4J A;  4F6V A;  3DYH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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