4LPGF

Crystal structure of human fpps in complex with cl01131
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
342
structure length
341
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 128
structure length 341
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4lpgF00
3MAVA 5IL8A 4MC8A 1RQIA 3OACB 1JFAA 3N45F 3P5PA 4LZCA 3WCBA 3KRCB 3WCDA 4KVYA 2F9KF 5I1UA 5DGSF 5IK6A 3OACA 2OGDA 3AQ0A 5ER8A 2E8XA 3LK5A 1HX9A 3N3LF 2F89F 3KRCA 4LIXA 3WE9A 1WL3A 3TFVA 5A0KA 4LLSA 4DI5A 3M02A 2RAHA 2DH4A 3M9UA 5DHIA 5IN8A 1N21A 4NUAA 2F92F 4DWBA 1WMWA 3IPIA 4JXYA 3S9VA 5DJPF 3RYWA 5IK9A 5B0IA 3M01A 4RXCA 3N1WF 3P5RA 4XQTF 4GA3A 3N46F 4LTVA 4F62A 3V1XA 3Q2ZA 2F94F 1V4EA 5DGNF 2ZEVA 5A0IA 5JA0F 4KK2A 1HXAA 4DZWA 3LVSA 5B0JA 2PS6A 1N1BA 5JV2F 5IKHA 1FPSA 3AQCB 4HD1A 3N0GA 4P0VA 1V4KA 4NKEA 3B7LA 3PH7A 2J5CA 1VG2A 4LFVF 4LXWA 2PS4A 3NPRA 4E1EA 1VG3A 4K10A 4NFIF 4JVJF 3KROB 5B0MA 4H5CF 5AHUB 3BNYA 1N22A 4KWDA 1YQ7A 1JFGA 4E9ZA 5AYPA 4OMGA 4XQSF 1UBXA 2ZCQA 3KROA 1YJ4A 1VG4A 3NF2A 2Z52A 4RYPA 4GAXA 1WL1A 2ZCRA 3IBAA 3N5JF 3SAEA 3V1VA 5DW7A 1V4JA 3N5HF 3LJIA 3WCCA 3ID0A 3LOMA 5DZ2A 3LDWA 2Z4ZA 4KVWA 5JV1F 4KVDA 1KIYA 4LPGF 3ZMCA 1VG7A 5B0LA 2E8WA 2ZCOA 5B00A 2E94A 5IKAA 2F8ZF 4LTZA 4NG6A 4EA2A 2AZLA 3WC9A 5A0JA 3G4DA 4DWGA 5CG5A 5ILZA 1V4IA 3M0GA 2Z4XA 3LMDA 4FP4A 3WCEA 5DIQF 2Z4YA 1YHMA 3ACWA 3CKEA 2PS8A 3WCIA 1YYQA 3W7FA 2OA6A 5C05A 3WCLA 3APZA 2E4OA 1YHLA 4RXAA 2J1PA 2OPNA 3QKCA 4N9UA 3VJ8A 3OABB 1KIZA 3WEJA 2Q9ZA 1YYUA 2Z4VA 5ILDA 3LGZB 4LZ0A 5EAUA 5HN9A 4PVYF 5E8LA 4MC3A 3OABA 4RNQA 1YV5A 4OKZA 3WEGA 3SDTA 4E9UA 2Z7HA 4Q23A 3N49F 1DI1A 3WJKA 3VJ9A 2Z7IA 3WSBA 1YYSA 2EWGA 4H5DF 4KKMA 5EROA 4KUXA 3ZL6A 1HM7A 3UCAA 4GP1A 4NFJF 3DYHA 3OYRA 2E95A 1YYTA 5HNAA 3LGKA 4QPFA 4EA1A 4LZ3A 2J1OA 3SDVA 5AFXA 4PVXF 1RTRA 4KVIA 1N24A 3ZMBA 3PYAA 3AE0A 3Q30A 4XQRF 3NRIA 2Z78A 5DJRF 4KFAA 2VF6A 3RMGA 2I19A 3N0FA 4RXDA 3S4JA 1UBWA 3WCFA 4KQ5A 2E8UA 3PDEA 3ICKA 4LOBA 4KQSA 4MC0A 5DJVF 2E93A 1VG6A 5EASA 5B0KA 1ZW5A 3LLWA 4OMHA 3ICZA 4N1ZF 2AZKA 2F7MF 3TS7A 1WL2A 5ILJA 4DEMF 3NPKA 4F6XA 4LA6A 3SDUA 2ZEUA 2ONHA 3TFPA 3BNXA 2E91A 3KRAB 3WJOA 2PS5A 5KSXF 2AEKA 1RQJA 2E8TA 3KRPB 3CC9A 4ZQ8A 4EA0A 1UBVA 5DHKA 3ADZA 3WCAA 4DXJA 2O1OA 3EGTA 3WCGA 3ZCDA 4LFGA 2E90A 3KRAA 1N23A 3VJBA 5JUZF 5ILYA 4QXSF 4H5EF 5ILIA 3ICNA 3N6KF 4LLTA 3KRPA 5IVGA 3WEHA 3WCJA 5AELA 3VJAA 2E92A 2QISA 4DHDA 3WCMA 3ACXA 3LG5A 3WJNA 5EATA 4KPDA 1WKZA 3VJEA 3VJDA 2PS7A 3KBKA 5IL3A 1N1ZA 5HN8A 4UMJA 3LSNA 2AELA 4LUUA 3V66A 5B02A 3RBMA 5E8KA 3DYGA 2Q9YA 4FJQA 3LZ9A 1UBYA 3WCHA 3WEKA 3TC1A 3ACYA 2FTZA 3ICMA 3P8RA 3M00A 4LFEA 5HN7A 3SDQA 1WY0A 4KPJA 4LPHF 1YYRA 3WEIA 3TFNA 3KB9A 5JV0F 5IM1A 4GP2A 4NKFA 4F6VA 2Q58A 1DGPA 2AZJA 3PYBA 4JYXA 4NFKF 5IMPA 1HM4A 2ZY1A 3EFQA 1EZFA 2H8OA 4P0WA 3RYEA 3P8LA 4LA5A 4OGUA 1V4HA 3QQVA 3WSAA 5ILKA 2Q80A 3KRFB 5H9DA 3LEEA 2P1CA 5E8HA 1HXCA 4KQUA 3Q2QA 3WEFA 3VJCA 2AETA 1HXGA 1YHKA 2ONGA 5ERNA 3KRFA 4P0XA 3N3DA 4WK5A 5ERMA 4JZXA 2ZCSA 3DYFA 3MZVA 3PKOA 5CG6A 3EZ3A 1PS1A 1WL0A 2OPMA 4JZBA 3SDRA 3ASXA 4JXNA 3N1VF 5IMNA 4OKMA 5ILHA 5DGMF 1N20A 2E8VA 3CP6A 2FORA 3AQBB 2F8CF 3P41A 2Z50A 3Q1OA 5IK0A 2Z4WA 3ZOUA 5IMIA 5B01A 5B03A 3G4FA 4RXEA 4L2XF
chains in the Genus database with same CATH superfamily
3MAVA 5IL8A 4MC8A 1RQIA 3OACB 1JFAA 3N45F 3P5PA 4LZCA 3WCBA 3KRCB 3WCDA 4KVYA 2F9KF 5I1UA 5DGSF 5IK6A 3OACA 2OGDA 3AQ0A 5ER8A 2E8XA 3LK5A 1HX9A 3N3LF 2F89F 3KRCA 4LIXA 3WE9A 1WL3A 3TFVA 5A0KA 4LLSA 4DI5A 3M02A 2RAHA 2DH4A 3M9UA 5DHIA 5IN8A 1N21A 4NUAA 2F92F 4DWBA 1WMWA 3IPIA 4JXYA 3S9VA 5DJPF 3RYWA 5IK9A 5B0IA 3M01A 4RXCA 3N1WF 3P5RA 4XQTF 4GA3A 3N46F 4LTVA 4F62A 3V1XA 3Q2ZA 2F94F 1V4EA 5DGNF 2ZEVA 5A0IA 5JA0F 4KK2A 1HXAA 4DZWA 3LVSA 5B0JA 2PS6A 1N1BA 5JV2F 5IKHA 1FPSA 3AQCB 4HD1A 3N0GA 4P0VA 1V4KA 4NKEA 3B7LA 3PH7A 2J5CA 1VG2A 4LFVF 4LXWA 2PS4A 3NPRA 4E1EA 1VG3A 4K10A 4NFIF 4JVJF 3KROB 5B0MA 4H5CF 5AHUB 3BNYA 1N22A 4KWDA 1YQ7A 1JFGA 4E9ZA 5AYPA 4OMGA 4XQSF 1UBXA 2ZCQA 3KROA 1YJ4A 1VG4A 3NF2A 2Z52A 4RYPA 4GAXA 1WL1A 2ZCRA 3IBAA 3N5JF 3SAEA 3V1VA 5DW7A 1V4JA 3N5HF 3LJIA 3WCCA 3ID0A 3LOMA 5DZ2A 3LDWA 2Z4ZA 4KVWA 5JV1F 4KVDA 1KIYA 4LPGF 3ZMCA 1VG7A 5B0LA 2E8WA 2ZCOA 5B00A 2E94A 5IKAA 2F8ZF 4LTZA 4NG6A 4EA2A 2AZLA 3WC9A 5A0JA 3G4DA 4DWGA 5CG5A 5ILZA 1V4IA 3M0GA 2Z4XA 3LMDA 4FP4A 3WCEA 5DIQF 2Z4YA 1YHMA 3ACWA 3CKEA 2PS8A 3WCIA 1YYQA 3W7FA 2OA6A 5C05A 3WCLA 3APZA 2E4OA 1YHLA 4RXAA 2J1PA 2OPNA 3QKCA 4N9UA 3VJ8A 3OABB 1KIZA 3WEJA 2Q9ZA 1YYUA 2Z4VA 5ILDA 3LGZB 4LZ0A 5EAUA 5HN9A 4PVYF 5E8LA 4MC3A 3OABA 4RNQA 1YV5A 4OKZA 3WEGA 3SDTA 4E9UA 2Z7HA 4Q23A 3N49F 1DI1A 3WJKA 3VJ9A 2Z7IA 3WSBA 1YYSA 2EWGA 4H5DF 4KKMA 5EROA 4KUXA 3ZL6A 1HM7A 3UCAA 4GP1A 4NFJF 3DYHA 3OYRA 2E95A 1YYTA 5HNAA 3LGKA 4QPFA 4EA1A 4LZ3A 2J1OA 3SDVA 5AFXA 4PVXF 1RTRA 4KVIA 1N24A 3ZMBA 3PYAA 3AE0A 3Q30A 4XQRF 3NRIA 2Z78A 5DJRF 4KFAA 2VF6A 3RMGA 2I19A 3N0FA 4RXDA 3S4JA 1UBWA 3WCFA 4KQ5A 2E8UA 3PDEA 3ICKA 4LOBA 4KQSA 4MC0A 5DJVF 2E93A 1VG6A 5EASA 5B0KA 1ZW5A 3LLWA 4OMHA 3ICZA 4N1ZF 2AZKA 2F7MF 3TS7A 1WL2A 5ILJA 4DEMF 3NPKA 4F6XA 4LA6A 3SDUA 2ZEUA 2ONHA 3TFPA 3BNXA 2E91A 3KRAB 3WJOA 2PS5A 5KSXF 2AEKA 1RQJA 2E8TA 3KRPB 3CC9A 4ZQ8A 4EA0A 1UBVA 5DHKA 3ADZA 3WCAA 4DXJA 2O1OA 3EGTA 3WCGA 3ZCDA 4LFGA 2E90A 3KRAA 1N23A 3VJBA 5JUZF 5ILYA 4QXSF 4H5EF 5ILIA 3ICNA 3N6KF 4LLTA 3KRPA 5IVGA 3WEHA 3WCJA 5AELA 3VJAA 2E92A 2QISA 4DHDA 3WCMA 3ACXA 3LG5A 3WJNA 5EATA 4KPDA 1WKZA 3VJEA 3VJDA 2PS7A 3KBKA 5IL3A 1N1ZA 5HN8A 4UMJA 3LSNA 2AELA 4LUUA 3V66A 5B02A 3RBMA 5E8KA 3DYGA 2Q9YA 4FJQA 3LZ9A 1UBYA 3WCHA 3WEKA 3TC1A 3ACYA 2FTZA 3ICMA 3P8RA 3M00A 4LFEA 5HN7A 3SDQA 1WY0A 4KPJA 4LPHF 1YYRA 3WEIA 3TFNA 3KB9A 5JV0F 5IM1A 4GP2A 4NKFA 4F6VA 2Q58A 1DGPA 2AZJA 3PYBA 4JYXA 4NFKF 5IMPA 1HM4A 2ZY1A 3EFQA 1EZFA 2H8OA 4P0WA 3RYEA 3P8LA 4LA5A 4OGUA 1V4HA 3QQVA 3WSAA 5ILKA 2Q80A 3KRFB 5H9DA 3LEEA 2P1CA 5E8HA 1HXCA 4KQUA 3Q2QA 3WEFA 3VJCA 2AETA 1HXGA 1YHKA 2ONGA 5ERNA 3KRFA 4P0XA 3N3DA 4WK5A 5ERMA 4JZXA 2ZCSA 3DYFA 3MZVA 3PKOA 5CG6A 3EZ3A 1PS1A 1WL0A 2OPMA 4JZBA 3SDRA 3ASXA 4JXNA 3N1VF 5IMNA 4OKMA 5ILHA 5DGMF 1N20A 2E8VA 3CP6A 2FORA 3AQBB 2F8CF 3P41A 2Z50A 3Q1OA 5IK0A 2Z4WA 3ZOUA 5IMIA 5B01A 5B03A 3G4FA 4RXEA 4L2XF
chains in the Genus database with same CATH topology
3MAVA 5IL8A 4MC8A 1RQIA 3OACB 1JFAA 3N45F 3P5PA 4LZCA 3WCBA 3KRCB 3WCDA 4KVYA 2F9KF 5I1UA 5DGSF 5IK6A 3OACA 2OGDA 3AQ0A 5ER8A 2E8XA 3LK5A 1HX9A 3N3LF 2F89F 3KRCA 4LIXA 3WE9A 1WL3A 3TFVA 5A0KA 4LLSA 4DI5A 3M02A 2RAHA 2DH4A 3M9UA 5DHIA 5IN8A 1N21A 4NUAA 2F92F 4DWBA 1WMWA 3IPIA 4JXYA 3S9VA 5DJPF 3RYWA 5IK9A 5B0IA 3M01A 4RXCA 3N1WF 3P5RA 4XQTF 4GA3A 3N46F 4LTVA 4F62A 3V1XA 3Q2ZA 2F94F 1V4EA 5DGNF 2ZEVA 5A0IA 5JA0F 4KK2A 1HXAA 4DZWA 3LVSA 5B0JA 2PS6A 1N1BA 5JV2F 5IKHA 1FPSA 3AQCB 4HD1A 3N0GA 4P0VA 1V4KA 4NKEA 3B7LA 3PH7A 2J5CA 1VG2A 4LFVF 4LXWA 2PS4A 3NPRA 4E1EA 1VG3A 4K10A 4NFIF 4JVJF 3KROB 5B0MA 4H5CF 5AHUB 3BNYA 1N22A 4KWDA 1YQ7A 1JFGA 4E9ZA 5AYPA 4OMGA 4XQSF 1UBXA 2ZCQA 3KROA 1YJ4A 1VG4A 3NF2A 2Z52A 4RYPA 4GAXA 1WL1A 2ZCRA 3IBAA 3N5JF 3SAEA 3V1VA 5DW7A 1V4JA 3N5HF 3LJIA 3WCCA 3ID0A 3LOMA 5DZ2A 3LDWA 2Z4ZA 4KVWA 5JV1F 4KVDA 1KIYA 4LPGF 3ZMCA 1VG7A 5B0LA 2E8WA 2ZCOA 5B00A 2E94A 5IKAA 2F8ZF 4LTZA 4NG6A 4EA2A 2AZLA 3WC9A 5A0JA 3G4DA 4DWGA 5CG5A 5ILZA 1V4IA 3M0GA 2Z4XA 3LMDA 4FP4A 3WCEA 5DIQF 2Z4YA 1YHMA 3ACWA 3CKEA 2PS8A 3WCIA 1YYQA 3W7FA 2OA6A 5C05A 3WCLA 3APZA 2E4OA 1YHLA 4RXAA 2J1PA 2OPNA 3QKCA 4N9UA 3VJ8A 3OABB 1KIZA 3WEJA 2Q9ZA 1YYUA 2Z4VA 5ILDA 3LGZB 4LZ0A 5EAUA 5HN9A 4PVYF 5E8LA 4MC3A 3OABA 4RNQA 1YV5A 4OKZA 3WEGA 3SDTA 4E9UA 2Z7HA 4Q23A 3N49F 1DI1A 3WJKA 3VJ9A 2Z7IA 3WSBA 1YYSA 2EWGA 4H5DF 4KKMA 5EROA 4KUXA 3ZL6A 1HM7A 3UCAA 4GP1A 4NFJF 3DYHA 3OYRA 2E95A 1YYTA 5HNAA 3LGKA 4QPFA 4EA1A 4LZ3A 2J1OA 3SDVA 5AFXA 4PVXF 1RTRA 4KVIA 1N24A 3ZMBA 3PYAA 3AE0A 3Q30A 4XQRF 3NRIA 2Z78A 5DJRF 4KFAA 2VF6A 3RMGA 2I19A 3N0FA 4RXDA 3S4JA 1UBWA 3WCFA 4KQ5A 2E8UA 3PDEA 3ICKA 4LOBA 4KQSA 4MC0A 5DJVF 2E93A 1VG6A 5EASA 5B0KA 1ZW5A 3LLWA 4OMHA 3ICZA 4N1ZF 2AZKA 2F7MF 3TS7A 1WL2A 5ILJA 4DEMF 3NPKA 4F6XA 4LA6A 3SDUA 2ZEUA 2ONHA 3TFPA 3BNXA 2E91A 3KRAB 3WJOA 2PS5A 5KSXF 2AEKA 1RQJA 2E8TA 3KRPB 3CC9A 4ZQ8A 4EA0A 1UBVA 5DHKA 3ADZA 3WCAA 4DXJA 2O1OA 3EGTA 3WCGA 3ZCDA 4LFGA 2E90A 3KRAA 1N23A 3VJBA 5JUZF 5ILYA 4QXSF 4H5EF 5ILIA 3ICNA 3N6KF 4LLTA 3KRPA 5IVGA 3WEHA 3WCJA 5AELA 3VJAA 2E92A 2QISA 4DHDA 3WCMA 3ACXA 3LG5A 3WJNA 5EATA 4KPDA 1WKZA 3VJEA 3VJDA 2PS7A 3KBKA 5IL3A 1N1ZA 5HN8A 4UMJA 3LSNA 2AELA 4LUUA 3V66A 5B02A 3RBMA 5E8KA 3DYGA 2Q9YA 4FJQA 3LZ9A 1UBYA 3WCHA 3WEKA 3TC1A 3ACYA 2FTZA 3ICMA 3P8RA 3M00A 4LFEA 5HN7A 3SDQA 1WY0A 4KPJA 4LPHF 1YYRA 3WEIA 3TFNA 3KB9A 5JV0F 5IM1A 4GP2A 4NKFA 4F6VA 2Q58A 1DGPA 2AZJA 3PYBA 4JYXA 4NFKF 5IMPA 1HM4A 2ZY1A 3EFQA 1EZFA 2H8OA 4P0WA 3RYEA 3P8LA 4LA5A 4OGUA 1V4HA 3QQVA 3WSAA 5ILKA 2Q80A 3KRFB 5H9DA 3LEEA 2P1CA 5E8HA 1HXCA 4KQUA 3Q2QA 3WEFA 3VJCA 2AETA 1HXGA 1YHKA 2ONGA 5ERNA 3KRFA 4P0XA 3N3DA 4WK5A 5ERMA 4JZXA 2ZCSA 3DYFA 3MZVA 3PKOA 5CG6A 3EZ3A 1PS1A 1WL0A 2OPMA 4JZBA 3SDRA 3ASXA 4JXNA 3N1VF 5IMNA 4OKMA 5ILHA 5DGMF 1N20A 2E8VA 3CP6A 2FORA 3AQBB 2F8CF 3P41A 2Z50A 3Q1OA 5IK0A 2Z4WA 3ZOUA 5IMIA 5B01A 5B03A 3G4FA 4RXEA 4L2XF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MAV A;  5IL8 A;  4MC8 A;  1RQI A;  3OAC B;  1JFA A;  3N45 F;  3P5P A;  4LZC A;  3WCB A;  3KRC B;  3WCD A;  4KVY A;  2F9K F;  5I1U A;  5DGS F;  5IK6 A;  3OAC A;  2OGD A;  3AQ0 A;  5ER8 A;  2E8X A;  3LK5 A;  1HX9 A;  3N3L F;  2F89 F;  3KRC A;  4LIX A;  3WE9 A;  1WL3 A;  3TFV A;  5A0K A;  4LLS A;  4DI5 A;  3M02 A;  2RAH A;  2DH4 A;  3M9U A;  5DHI A;  5IN8 A;  1N21 A;  4NUA A;  2F92 F;  4DWB A;  1WMW A;  3IPI A;  4JXY A;  3S9V A;  5DJP F;  3RYW A;  5IK9 A;  5B0I A;  3M01 A;  4RXC A;  3N1W F;  3P5R A;  4XQT F;  4GA3 A;  3N46 F;  4LTV A;  4F62 A;  3V1X A;  3Q2Z A;  2F94 F;  1V4E A;  5DGN F;  2ZEV A;  5A0I A;  5JA0 F;  4KK2 A;  1HXA A;  4DZW A;  3LVS A;  5B0J A;  2PS6 A;  1N1B A;  5JV2 F;  5IKH A;  1FPS A;  3AQC B;  4HD1 A;  3N0G A;  4P0V A;  1V4K A;  4NKE A;  3B7L A;  3PH7 A;  2J5C A;  1VG2 A;  4LFV F;  4LXW A;  2PS4 A;  3NPR A;  4E1E A;  1VG3 A;  4K10 A;  4NFI F;  4JVJ F;  3KRO B;  5B0M A;  4H5C F;  5AHU B;  3BNY A;  1N22 A;  4KWD A;  1YQ7 A;  1JFG A;  4E9Z A;  5AYP A;  4OMG A;  4XQS F;  1UBX A;  2ZCQ A;  3KRO A;  1YJ4 A;  1VG4 A;  3NF2 A;  2Z52 A;  4RYP A;  4GAX A;  1WL1 A;  2ZCR A;  3IBA A;  3N5J F;  3SAE A;  3V1V A;  5DW7 A;  1V4J A;  3N5H F;  3LJI A;  3WCC A;  3ID0 A;  3LOM A;  5DZ2 A;  3LDW A;  2Z4Z A;  4KVW A;  5JV1 F;  4KVD A;  1KIY A;  4LPG F;  3ZMC A;  1VG7 A;  5B0L A;  2E8W A;  2ZCO A;  5B00 A;  2E94 A;  5IKA A;  2F8Z F;  4LTZ A;  4NG6 A;  4EA2 A;  2AZL A;  3WC9 A;  5A0J A;  3G4D A;  4DWG A;  5CG5 A;  5ILZ A;  1V4I A;  3M0G A;  2Z4X A;  3LMD A;  4FP4 A;  3WCE A;  5DIQ F;  2Z4Y A;  1YHM A;  3ACW A;  3CKE A;  2PS8 A;  3WCI A;  1YYQ A;  3W7F A;  2OA6 A;  5C05 A;  3WCL A;  3APZ A;  2E4O A;  1YHL A;  4RXA A;  2J1P A;  2OPN A;  3QKC A;  4N9U A;  3VJ8 A;  3OAB B;  1KIZ A;  3WEJ A;  2Q9Z A;  1YYU A;  2Z4V A;  5ILD A;  3LGZ B;  4LZ0 A;  5EAU A;  5HN9 A;  4PVY F;  5E8L A;  4MC3 A;  3OAB A;  4RNQ A;  1YV5 A;  4OKZ A;  3WEG A;  3SDT A;  4E9U A;  2Z7H A;  4Q23 A;  3N49 F;  1DI1 A;  3WJK A;  3VJ9 A;  2Z7I A;  3WSB A;  1YYS A;  2EWG A;  4H5D F;  4KKM A;  5ERO A;  4KUX A;  3ZL6 A;  1HM7 A;  3UCA A;  4GP1 A;  4NFJ F;  3DYH A;  3OYR A;  2E95 A;  1YYT A;  5HNA A;  3LGK A;  4QPF A;  4EA1 A;  4LZ3 A;  2J1O A;  3SDV A;  5AFX A;  4PVX F;  1RTR A;  4KVI A;  1N24 A;  3ZMB A;  3PYA A;  3AE0 A;  3Q30 A;  4XQR F;  3NRI A;  2Z78 A;  5DJR F;  4KFA A;  2VF6 A;  3RMG A;  2I19 A;  3N0F A;  4RXD A;  3S4J A;  1UBW A;  3WCF A;  4KQ5 A;  2E8U A;  3PDE A;  3ICK A;  4LOB A;  4KQS A;  4MC0 A;  5DJV F;  2E93 A;  1VG6 A;  5EAS A;  5B0K A;  1ZW5 A;  3LLW A;  4OMH A;  3ICZ A;  4N1Z F;  2AZK A;  2F7M F;  3TS7 A;  1WL2 A;  5ILJ A;  4DEM F;  3NPK A;  4F6X A;  4LA6 A;  3SDU A;  2ZEU A;  2ONH A;  3TFP A;  3BNX A;  2E91 A;  3KRA B;  3WJO A;  2PS5 A;  5KSX F;  2AEK A;  1RQJ A;  2E8T A;  3KRP B;  3CC9 A;  4ZQ8 A;  4EA0 A;  1UBV A;  5DHK A;  3ADZ A;  3WCA A;  4DXJ A;  2O1O A;  3EGT A;  3WCG A;  3ZCD A;  4LFG A;  2E90 A;  3KRA A;  1N23 A;  3VJB A;  5JUZ F;  5ILY A;  4QXS F;  4H5E F;  5ILI A;  3ICN A;  3N6K F;  4LLT A;  3KRP A;  5IVG A;  3WEH A;  3WCJ A;  5AEL A;  3VJA A;  2E92 A;  2QIS A;  4DHD A;  3WCM A;  3ACX A;  3LG5 A;  3WJN A;  5EAT A;  4KPD A;  1WKZ A;  3VJE A;  3VJD A;  2PS7 A;  3KBK A;  5IL3 A;  1N1Z A;  5HN8 A;  4UMJ A;  3LSN A;  2AEL A;  4LUU A;  3V66 A;  5B02 A;  3RBM A;  5E8K A;  3DYG A;  2Q9Y A;  4FJQ A;  3LZ9 A;  1UBY A;  3WCH A;  3WEK A;  3TC1 A;  3ACY A;  2FTZ A;  3ICM A;  3P8R A;  3M00 A;  4LFE A;  5HN7 A;  3SDQ A;  1WY0 A;  4KPJ A;  4LPH F;  1YYR A;  3WEI A;  3TFN A;  3KB9 A;  5JV0 F;  5IM1 A;  4GP2 A;  4NKF A;  4F6V A;  2Q58 A;  1DGP A;  2AZJ A;  3PYB A;  4JYX A;  4NFK F;  5IMP A;  1HM4 A;  2ZY1 A;  3EFQ A;  1EZF A;  2H8O A;  4P0W A;  3RYE A;  3P8L A;  4LA5 A;  4OGU A;  1V4H A;  3QQV A;  3WSA A;  5ILK A;  2Q80 A;  3KRF B;  5H9D A;  3LEE A;  2P1C A;  5E8H A;  1HXC A;  4KQU A;  3Q2Q A;  3WEF A;  3VJC A;  2AET A;  1HXG A;  1YHK A;  2ONG A;  5ERN A;  3KRF A;  4P0X A;  3N3D A;  4WK5 A;  5ERM A;  4JZX A;  2ZCS A;  3DYF A;  3MZV A;  3PKO A;  5CG6 A;  3EZ3 A;  1PS1 A;  1WL0 A;  2OPM A;  4JZB A;  3SDR A;  3ASX A;  4JXN A;  3N1V F;  5IMN A;  4OKM A;  5ILH A;  5DGM F;  1N20 A;  2E8V A;  3CP6 A;  2FOR A;  3AQB B;  2F8C F;  3P41 A;  2Z50 A;  3Q1O A;  5IK0 A;  2Z4W A;  3ZOU A;  5IMI A;  5B01 A;  5B03 A;  3G4F A;  4RXE A;  4L2X F; 
#chains in the Genus database with same CATH topology
 3MAV A;  5IL8 A;  4MC8 A;  1RQI A;  3OAC B;  1JFA A;  3N45 F;  3P5P A;  4LZC A;  3WCB A;  3KRC B;  3WCD A;  4KVY A;  2F9K F;  5I1U A;  5DGS F;  5IK6 A;  3OAC A;  2OGD A;  3AQ0 A;  5ER8 A;  2E8X A;  3LK5 A;  1HX9 A;  3N3L F;  2F89 F;  3KRC A;  4LIX A;  3WE9 A;  1WL3 A;  3TFV A;  5A0K A;  4LLS A;  4DI5 A;  3M02 A;  2RAH A;  2DH4 A;  3M9U A;  5DHI A;  5IN8 A;  1N21 A;  4NUA A;  2F92 F;  4DWB A;  1WMW A;  3IPI A;  4JXY A;  3S9V A;  5DJP F;  3RYW A;  5IK9 A;  5B0I A;  3M01 A;  4RXC A;  3N1W F;  3P5R A;  4XQT F;  4GA3 A;  3N46 F;  4LTV A;  4F62 A;  3V1X A;  3Q2Z A;  2F94 F;  1V4E A;  5DGN F;  2ZEV A;  5A0I A;  5JA0 F;  4KK2 A;  1HXA A;  4DZW A;  3LVS A;  5B0J A;  2PS6 A;  1N1B A;  5JV2 F;  5IKH A;  1FPS A;  3AQC B;  4HD1 A;  3N0G A;  4P0V A;  1V4K A;  4NKE A;  3B7L A;  3PH7 A;  2J5C A;  1VG2 A;  4LFV F;  4LXW A;  2PS4 A;  3NPR A;  4E1E A;  1VG3 A;  4K10 A;  4NFI F;  4JVJ F;  3KRO B;  5B0M A;  4H5C F;  5AHU B;  3BNY A;  1N22 A;  4KWD A;  1YQ7 A;  1JFG A;  4E9Z A;  5AYP A;  4OMG A;  4XQS F;  1UBX A;  2ZCQ A;  3KRO A;  1YJ4 A;  1VG4 A;  3NF2 A;  2Z52 A;  4RYP A;  4GAX A;  1WL1 A;  2ZCR A;  3IBA A;  3N5J F;  3SAE A;  3V1V A;  5DW7 A;  1V4J A;  3N5H F;  3LJI A;  3WCC A;  3ID0 A;  3LOM A;  5DZ2 A;  3LDW A;  2Z4Z A;  4KVW A;  5JV1 F;  4KVD A;  1KIY A;  4LPG F;  3ZMC A;  1VG7 A;  5B0L A;  2E8W A;  2ZCO A;  5B00 A;  2E94 A;  5IKA A;  2F8Z F;  4LTZ A;  4NG6 A;  4EA2 A;  2AZL A;  3WC9 A;  5A0J A;  3G4D A;  4DWG A;  5CG5 A;  5ILZ A;  1V4I A;  3M0G A;  2Z4X A;  3LMD A;  4FP4 A;  3WCE A;  5DIQ F;  2Z4Y A;  1YHM A;  3ACW A;  3CKE A;  2PS8 A;  3WCI A;  1YYQ A;  3W7F A;  2OA6 A;  5C05 A;  3WCL A;  3APZ A;  2E4O A;  1YHL A;  4RXA A;  2J1P A;  2OPN A;  3QKC A;  4N9U A;  3VJ8 A;  3OAB B;  1KIZ A;  3WEJ A;  2Q9Z A;  1YYU A;  2Z4V A;  5ILD A;  3LGZ B;  4LZ0 A;  5EAU A;  5HN9 A;  4PVY F;  5E8L A;  4MC3 A;  3OAB A;  4RNQ A;  1YV5 A;  4OKZ A;  3WEG A;  3SDT A;  4E9U A;  2Z7H A;  4Q23 A;  3N49 F;  1DI1 A;  3WJK A;  3VJ9 A;  2Z7I A;  3WSB A;  1YYS A;  2EWG A;  4H5D F;  4KKM A;  5ERO A;  4KUX A;  3ZL6 A;  1HM7 A;  3UCA A;  4GP1 A;  4NFJ F;  3DYH A;  3OYR A;  2E95 A;  1YYT A;  5HNA A;  3LGK A;  4QPF A;  4EA1 A;  4LZ3 A;  2J1O A;  3SDV A;  5AFX A;  4PVX F;  1RTR A;  4KVI A;  1N24 A;  3ZMB A;  3PYA A;  3AE0 A;  3Q30 A;  4XQR F;  3NRI A;  2Z78 A;  5DJR F;  4KFA A;  2VF6 A;  3RMG A;  2I19 A;  3N0F A;  4RXD A;  3S4J A;  1UBW A;  3WCF A;  4KQ5 A;  2E8U A;  3PDE A;  3ICK A;  4LOB A;  4KQS A;  4MC0 A;  5DJV F;  2E93 A;  1VG6 A;  5EAS A;  5B0K A;  1ZW5 A;  3LLW A;  4OMH A;  3ICZ A;  4N1Z F;  2AZK A;  2F7M F;  3TS7 A;  1WL2 A;  5ILJ A;  4DEM F;  3NPK A;  4F6X A;  4LA6 A;  3SDU A;  2ZEU A;  2ONH A;  3TFP A;  3BNX A;  2E91 A;  3KRA B;  3WJO A;  2PS5 A;  5KSX F;  2AEK A;  1RQJ A;  2E8T A;  3KRP B;  3CC9 A;  4ZQ8 A;  4EA0 A;  1UBV A;  5DHK A;  3ADZ A;  3WCA A;  4DXJ A;  2O1O A;  3EGT A;  3WCG A;  3ZCD A;  4LFG A;  2E90 A;  3KRA A;  1N23 A;  3VJB A;  5JUZ F;  5ILY A;  4QXS F;  4H5E F;  5ILI A;  3ICN A;  3N6K F;  4LLT A;  3KRP A;  5IVG A;  3WEH A;  3WCJ A;  5AEL A;  3VJA A;  2E92 A;  2QIS A;  4DHD A;  3WCM A;  3ACX A;  3LG5 A;  3WJN A;  5EAT A;  4KPD A;  1WKZ A;  3VJE A;  3VJD A;  2PS7 A;  3KBK A;  5IL3 A;  1N1Z A;  5HN8 A;  4UMJ A;  3LSN A;  2AEL A;  4LUU A;  3V66 A;  5B02 A;  3RBM A;  5E8K A;  3DYG A;  2Q9Y A;  4FJQ A;  3LZ9 A;  1UBY A;  3WCH A;  3WEK A;  3TC1 A;  3ACY A;  2FTZ A;  3ICM A;  3P8R A;  3M00 A;  4LFE A;  5HN7 A;  3SDQ A;  1WY0 A;  4KPJ A;  4LPH F;  1YYR A;  3WEI A;  3TFN A;  3KB9 A;  5JV0 F;  5IM1 A;  4GP2 A;  4NKF A;  4F6V A;  2Q58 A;  1DGP A;  2AZJ A;  3PYB A;  4JYX A;  4NFK F;  5IMP A;  1HM4 A;  2ZY1 A;  3EFQ A;  1EZF A;  2H8O A;  4P0W A;  3RYE A;  3P8L A;  4LA5 A;  4OGU A;  1V4H A;  3QQV A;  3WSA A;  5ILK A;  2Q80 A;  3KRF B;  5H9D A;  3LEE A;  2P1C A;  5E8H A;  1HXC A;  4KQU A;  3Q2Q A;  3WEF A;  3VJC A;  2AET A;  1HXG A;  1YHK A;  2ONG A;  5ERN A;  3KRF A;  4P0X A;  3N3D A;  4WK5 A;  5ERM A;  4JZX A;  2ZCS A;  3DYF A;  3MZV A;  3PKO A;  5CG6 A;  3EZ3 A;  1PS1 A;  1WL0 A;  2OPM A;  4JZB A;  3SDR A;  3ASX A;  4JXN A;  3N1V F;  5IMN A;  4OKM A;  5ILH A;  5DGM F;  1N20 A;  2E8V A;  3CP6 A;  2FOR A;  3AQB B;  2F8C F;  3P41 A;  2Z50 A;  3Q1O A;  5IK0 A;  2Z4W A;  3ZOU A;  5IMI A;  5B01 A;  5B03 A;  3G4F A;  4RXE A;  4L2X F; 
#chains in the Genus database with same CATH homology
 3MAV A;  5IL8 A;  4MC8 A;  1RQI A;  3OAC B;  1JFA A;  3N45 F;  3P5P A;  4LZC A;  3WCB A;  3KRC B;  3WCD A;  4KVY A;  2F9K F;  5I1U A;  5DGS F;  5IK6 A;  3OAC A;  2OGD A;  3AQ0 A;  5ER8 A;  2E8X A;  3LK5 A;  1HX9 A;  3N3L F;  2F89 F;  3KRC A;  4LIX A;  3WE9 A;  1WL3 A;  3TFV A;  5A0K A;  4LLS A;  4DI5 A;  3M02 A;  2RAH A;  2DH4 A;  3M9U A;  5DHI A;  5IN8 A;  1N21 A;  4NUA A;  2F92 F;  4DWB A;  1WMW A;  3IPI A;  4JXY A;  3S9V A;  5DJP F;  3RYW A;  5IK9 A;  5B0I A;  3M01 A;  4RXC A;  3N1W F;  3P5R A;  4XQT F;  4GA3 A;  3N46 F;  4LTV A;  4F62 A;  3V1X A;  3Q2Z A;  2F94 F;  1V4E A;  5DGN F;  2ZEV A;  5A0I A;  5JA0 F;  4KK2 A;  1HXA A;  4DZW A;  3LVS A;  5B0J A;  2PS6 A;  1N1B A;  5JV2 F;  5IKH A;  1FPS A;  3AQC B;  4HD1 A;  3N0G A;  4P0V A;  1V4K A;  4NKE A;  3B7L A;  3PH7 A;  2J5C A;  1VG2 A;  4LFV F;  4LXW A;  2PS4 A;  3NPR A;  4E1E A;  1VG3 A;  4K10 A;  4NFI F;  4JVJ F;  3KRO B;  5B0M A;  4H5C F;  5AHU B;  3BNY A;  1N22 A;  4KWD A;  1YQ7 A;  1JFG A;  4E9Z A;  5AYP A;  4OMG A;  4XQS F;  1UBX A;  2ZCQ A;  3KRO A;  1YJ4 A;  1VG4 A;  3NF2 A;  2Z52 A;  4RYP A;  4GAX A;  1WL1 A;  2ZCR A;  3IBA A;  3N5J F;  3SAE A;  3V1V A;  5DW7 A;  1V4J A;  3N5H F;  3LJI A;  3WCC A;  3ID0 A;  3LOM A;  5DZ2 A;  3LDW A;  2Z4Z A;  4KVW A;  5JV1 F;  4KVD A;  1KIY A;  4LPG F;  3ZMC A;  1VG7 A;  5B0L A;  2E8W A;  2ZCO A;  5B00 A;  2E94 A;  5IKA A;  2F8Z F;  4LTZ A;  4NG6 A;  4EA2 A;  2AZL A;  3WC9 A;  5A0J A;  3G4D A;  4DWG A;  5CG5 A;  5ILZ A;  1V4I A;  3M0G A;  2Z4X A;  3LMD A;  4FP4 A;  3WCE A;  5DIQ F;  2Z4Y A;  1YHM A;  3ACW A;  3CKE A;  2PS8 A;  3WCI A;  1YYQ A;  3W7F A;  2OA6 A;  5C05 A;  3WCL A;  3APZ A;  2E4O A;  1YHL A;  4RXA A;  2J1P A;  2OPN A;  3QKC A;  4N9U A;  3VJ8 A;  3OAB B;  1KIZ A;  3WEJ A;  2Q9Z A;  1YYU A;  2Z4V A;  5ILD A;  3LGZ B;  4LZ0 A;  5EAU A;  5HN9 A;  4PVY F;  5E8L A;  4MC3 A;  3OAB A;  4RNQ A;  1YV5 A;  4OKZ A;  3WEG A;  3SDT A;  4E9U A;  2Z7H A;  4Q23 A;  3N49 F;  1DI1 A;  3WJK A;  3VJ9 A;  2Z7I A;  3WSB A;  1YYS A;  2EWG A;  4H5D F;  4KKM A;  5ERO A;  4KUX A;  3ZL6 A;  1HM7 A;  3UCA A;  4GP1 A;  4NFJ F;  3DYH A;  3OYR A;  2E95 A;  1YYT A;  5HNA A;  3LGK A;  4QPF A;  4EA1 A;  4LZ3 A;  2J1O A;  3SDV A;  5AFX A;  4PVX F;  1RTR A;  4KVI A;  1N24 A;  3ZMB A;  3PYA A;  3AE0 A;  3Q30 A;  4XQR F;  3NRI A;  2Z78 A;  5DJR F;  4KFA A;  2VF6 A;  3RMG A;  2I19 A;  3N0F A;  4RXD A;  3S4J A;  1UBW A;  3WCF A;  4KQ5 A;  2E8U A;  3PDE A;  3ICK A;  4LOB A;  4KQS A;  4MC0 A;  5DJV F;  2E93 A;  1VG6 A;  5EAS A;  5B0K A;  1ZW5 A;  3LLW A;  4OMH A;  3ICZ A;  4N1Z F;  2AZK A;  2F7M F;  3TS7 A;  1WL2 A;  5ILJ A;  4DEM F;  3NPK A;  4F6X A;  4LA6 A;  3SDU A;  2ZEU A;  2ONH A;  3TFP A;  3BNX A;  2E91 A;  3KRA B;  3WJO A;  2PS5 A;  5KSX F;  2AEK A;  1RQJ A;  2E8T A;  3KRP B;  3CC9 A;  4ZQ8 A;  4EA0 A;  1UBV A;  5DHK A;  3ADZ A;  3WCA A;  4DXJ A;  2O1O A;  3EGT A;  3WCG A;  3ZCD A;  4LFG A;  2E90 A;  3KRA A;  1N23 A;  3VJB A;  5JUZ F;  5ILY A;  4QXS F;  4H5E F;  5ILI A;  3ICN A;  3N6K F;  4LLT A;  3KRP A;  5IVG A;  3WEH A;  3WCJ A;  5AEL A;  3VJA A;  2E92 A;  2QIS A;  4DHD A;  3WCM A;  3ACX A;  3LG5 A;  3WJN A;  5EAT A;  4KPD A;  1WKZ A;  3VJE A;  3VJD A;  2PS7 A;  3KBK A;  5IL3 A;  1N1Z A;  5HN8 A;  4UMJ A;  3LSN A;  2AEL A;  4LUU A;  3V66 A;  5B02 A;  3RBM A;  5E8K A;  3DYG A;  2Q9Y A;  4FJQ A;  3LZ9 A;  1UBY A;  3WCH A;  3WEK A;  3TC1 A;  3ACY A;  2FTZ A;  3ICM A;  3P8R A;  3M00 A;  4LFE A;  5HN7 A;  3SDQ A;  1WY0 A;  4KPJ A;  4LPH F;  1YYR A;  3WEI A;  3TFN A;  3KB9 A;  5JV0 F;  5IM1 A;  4GP2 A;  4NKF A;  4F6V A;  2Q58 A;  1DGP A;  2AZJ A;  3PYB A;  4JYX A;  4NFK F;  5IMP A;  1HM4 A;  2ZY1 A;  3EFQ A;  1EZF A;  2H8O A;  4P0W A;  3RYE A;  3P8L A;  4LA5 A;  4OGU A;  1V4H A;  3QQV A;  3WSA A;  5ILK A;  2Q80 A;  3KRF B;  5H9D A;  3LEE A;  2P1C A;  5E8H A;  1HXC A;  4KQU A;  3Q2Q A;  3WEF A;  3VJC A;  2AET A;  1HXG A;  1YHK A;  2ONG A;  5ERN A;  3KRF A;  4P0X A;  3N3D A;  4WK5 A;  5ERM A;  4JZX A;  2ZCS A;  3DYF A;  3MZV A;  3PKO A;  5CG6 A;  3EZ3 A;  1PS1 A;  1WL0 A;  2OPM A;  4JZB A;  3SDR A;  3ASX A;  4JXN A;  3N1V F;  5IMN A;  4OKM A;  5ILH A;  5DGM F;  1N20 A;  2E8V A;  3CP6 A;  2FOR A;  3AQB B;  2F8C F;  3P41 A;  2Z50 A;  3Q1O A;  5IK0 A;  2Z4W A;  3ZOU A;  5IMI A;  5B01 A;  5B03 A;  3G4F A;  4RXE A;  4L2X F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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