4LUPA

Crystal structure of the complex formed by region of e. coli sigmae bound to its -10 element non template strand
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
91
structure length
91
Chain Sequence
LTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRLEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for -10 promoter element melting by environmentally induced sigma factors.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Escherichia coli
molecule keywords RNA polymerase sigma factor
total genus 36
structure length 91
sequence length 91
chains with identical sequence C
ec nomenclature
pdb deposition date 2013-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04542 Sigma70_r2 Sigma-70 region 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.10 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 4lupA00
4ZQHA 1G5AA 3WQRA 4ZQFA 3A14A 2MAOA 3ZHYA 4ZQEA 2Y1CA 2Y1GA 4RCVA 3A06A 4NQWA 4Y6PA 2MAPA 3AU9A 1ONNA 3AUAA 1Q0HA 1Q0QA 1R0KA 2O7GA 4KP7A 1H3LA 3UERA 1SC5A 4FLOA 3CZEA 3ZI0A 2JD0A 1JGIA 1K5HA 4Y6SA 2C82A 2Y1FA 3WQQA 2WPGA 4OOEA 2Y1DA 3IIEA 3RASA 1MVYA 2JD1A 3T0YA 3ZHZA 1MW0A 1JG9A 1MW1A 2Y1EA 1JVSA 4CXFA 4FLSA 5JAZA 4ZQGA 1MW3A 1R0LA 1Q0LA 4Y67A 3R0IA 3CZLA 4ZN6A 5JO0A 5JMPA 4A03A 2JCVA 4OOFA 3AU8A 5JMWA 5JNLA 3UCQA 4FLQA 3CZKA 1RP3A 4FLRA 1S46A 2EGHA 3ANMA 5DULA 3ZHXA 1ONPA 4LUPA 2JD2A 1MW2A 3ANNA 3CZGA 1T1RA 4GAEA 5JBIA 1ONOA 4AICA 2JCYA 1ZS2A 3WQSB 1OR7A 3UEQA 5JC1A 4Y6RA 1T1SA 2JCXA 3ANLA 4AYSA
chains in the Genus database with same CATH superfamily
4ZQHA 4L2LA 3FH8A 4GAAA 4QPEA 1G5AA 3VVLA 3WQRA 3FTWA 3FU3A 3FUIA 4ZQFA 3FULA 3A14A 4XNDA 4XMZA 2XQ0A 4QUOA 3FUKA 2A7OA 2MAOA 3ZHYA 2WZFA 4ZX6A 4ZQEA 3CHRA 4AR9A 2Y1CA 4ZX5A 2Y1GA 4RCVA 3CHOA 4QIRA 3CHPA 3A06A 4JNDA 4XO3A 3CIAA 4NQWA 3FTZA 4Y6PA 2MAPA 3AU9A 3B2XA 4XMUA 3FU0A 1ONNA 4R5TA 2ZXGA 3AUAA 3FTVA 1Q0HA 1Q0QA 1R0KA 3JSZA 2O7GA 1H3LA 4KP7A 3UERA 1SC5A 2FFLA 4FLOA 4AR1A 4K5PA 3CZEA 3ZI0A 4XN2A 4PVBA 4ZW3A 4XNBA 3CHQA 4R7LA 5EV7A 3RC3A 4AR8A 2JD0A 1SQMA 4XN5A 1JGIA 4Q4EA 5HNFA 3KEDA 1K5HA 4ZW6A 4XMVA 2RJIA 3B37A 3FHEA 4XO4A 2QVWA 2C82A 2Y1FA 3FUDA 2WPGA 4Y6SA 3WQQA 4OOEA 2Y1DA 3B3BA 3IIEA 4R5XA 3RASA 1MVYA 3FTUA 4XN4A 2JD1A 5FWQA 3QJXA 4XN1A 3HW2A 3T0YA 4ARFA 3ZHZA 2R72A 4ZQTA 1MW0A 1JG9A 4PW4A 4K5OA 4XMXA 1MW1A 2Y1EA 2VLAA 5HNHA 1JVSA 4CXFA 3PUUA 4DPRA 4XMTA 4FLSA 3FUFA 4RVBA 4MKTA 3B34A 4ZW8A 5AENA 2QJ1A 3FTSA 5JAZA 4ZQGA 3FH7A 1MW3A 1R0LA 3U9WA 1Q0LA 1X3WA 2R70A 2WZGA 3B7SA 2DQ6A 3VVMA 3CHSA 4QHPA 4Y67A 3R0IA 3CZLA 1X3ZA 3Q43A 1HS6A 4ZN6A 4MS6A 5JO0A 4XO5A 4XMWA 5DLLA 5JMPA 4ZX3A 4K5LA 4A03A 4K5MA 2JCVA 4OOFA 4QMEA 3AU8A 5JMWA 2HPTA 5JNLA 2XPZA 3FUEA 3UCQA 3B7TA 4FLQA 3CZKA 3FUHA 3B7UX 1GW6A 5BPPA 4XNAA 2GTQA 3B7RL 2JV7A 4XN8A 2B61A 3FU6A 4Q4IA 1RP3A 3FH5A 4FLRA 1S46A 3FTXA 2EGHA 2C5ZA 4XN9A 4K5NA 2VJ8A 3ANMA 3FUJA 5DULA 4RSYA 1ONPA 3ZHXA 2XPYA 3CXBA 3JT1A 4LUPA 4PU2A 4BKXA 2JD2A 4XN7A 3FTYA 1MW2A 3ANNA 2DQMA 3CZGA 1T1RA 2PUSA 3FUMA 2PGGA 4X2UA 2PL5A 2R59A 4FCAA 3Q44A 4GAEA 5JBIA 1ONOA 3EBGA 2HPOA 4ZW7A 4AICA 3T8VA 4R5VA 2JCYA 4J3BA 1ZS2A 3EBIA 3RC8A 3FUNA 3WQSB 1OR7A 3UEQA 3FU5A 5DYFA 5JC1A 4Y6RA 5HLTA 1T1SA 4ZX4A 1SG7A 2JCXA 1H19A 3EBHA 4ZW5A 3ANLA 4AYSA 3B2PA
chains in the Genus database with same CATH topology
4ZQHA 4L2LA 3FH8A 4GAAA 4QPEA 1G5AA 3VVLA 3WQRA 3FTWA 3FU3A 3FUIA 4ZQFA 3FULA 3A14A 4XNDA 4XMZA 2XQ0A 4QUOA 3FUKA 2A7OA 2MAOA 3ZHYA 2WZFA 4ZX6A 4ZQEA 3CHRA 4AR9A 2Y1CA 4ZX5A 2Y1GA 4RCVA 3CHOA 4QIRA 3CHPA 3A06A 4JNDA 4XO3A 3CIAA 4NQWA 3FTZA 4Y6PA 2MAPA 3AU9A 3B2XA 4XMUA 3FU0A 1ONNA 4R5TA 2ZXGA 3AUAA 3FTVA 1Q0HA 1Q0QA 1R0KA 3JSZA 2O7GA 1H3LA 4KP7A 3UERA 1SC5A 2FFLA 4FLOA 4AR1A 4K5PA 3CZEA 3ZI0A 4XN2A 4PVBA 4ZW3A 4XNBA 3CHQA 4R7LA 5EV7A 3RC3A 4AR8A 2JD0A 1SQMA 4XN5A 1JGIA 4Q4EA 5HNFA 3KEDA 1K5HA 4ZW6A 4XMVA 2RJIA 3B37A 3FHEA 4XO4A 2QVWA 2C82A 2Y1FA 3FUDA 2WPGA 4Y6SA 3WQQA 4OOEA 2Y1DA 3B3BA 3IIEA 4R5XA 3RASA 1MVYA 3FTUA 4XN4A 2JD1A 5FWQA 3QJXA 4XN1A 3T0YA 4ARFA 3ZHZA 2R72A 4ZQTA 1MW0A 1JG9A 4PW4A 4K5OA 4XMXA 1MW1A 2Y1EA 2VLAA 5HNHA 1JVSA 4CXFA 3PUUA 4DPRA 4XMTA 4FLSA 3FUFA 4RVBA 4MKTA 3B34A 4ZW8A 5AENA 2QJ1A 3FTSA 5JAZA 4ZQGA 3FH7A 1MW3A 1R0LA 3U9WA 1Q0LA 1X3WA 2R70A 2WZGA 3B7SA 2DQ6A 3VVMA 3CHSA 4QHPA 4Y67A 3R0IA 3CZLA 1X3ZA 3Q43A 1HS6A 4ZN6A 4MS6A 5JO0A 4XO5A 4XMWA 5DLLA 5JMPA 4ZX3A 4K5LA 4A03A 4K5MA 2JCVA 4OOFA 4QMEA 3AU8A 5JMWA 2HPTA 5JNLA 2XPZA 3FUEA 3UCQA 3B7TA 4FLQA 3CZKA 3FUHA 3B7UX 1GW6A 5BPPA 4XNAA 2GTQA 3B7RL 2JV7A 4XN8A 2B61A 3FU6A 4Q4IA 1RP3A 3FH5A 4FLRA 1S46A 3FTXA 2EGHA 2C5ZA 4XN9A 4K5NA 2VJ8A 3ANMA 3FUJA 5DULA 4RSYA 1ONPA 3ZHXA 2XPYA 3JT1A 4LUPA 4PU2A 4BKXA 2JD2A 4XN7A 3FTYA 1MW2A 3ANNA 2DQMA 3CZGA 1T1RA 2PUSA 3FUMA 2PGGA 4X2UA 2PL5A 2R59A 4FCAA 3Q44A 4GAEA 5JBIA 1ONOA 3EBGA 2HPOA 4ZW7A 4AICA 3T8VA 4R5VA 2JCYA 4J3BA 1ZS2A 3EBIA 3RC8A 3FUNA 3WQSB 1OR7A 3UEQA 3FU5A 5DYFA 5JC1A 4Y6RA 5HLTA 1T1SA 4ZX4A 1SG7A 2JCXA 1H19A 3EBHA 4ZW5A 3ANLA 4AYSA 3B2PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZQH A;  1G5A A;  3WQR A;  4ZQF A;  3A14 A;  2MAO A;  3ZHY A;  4ZQE A;  2Y1C A;  2Y1G A;  4RCV A;  3A06 A;  4NQW A;  4Y6P A;  2MAP A;  3AU9 A;  1ONN A;  3AUA A;  1Q0H A;  1Q0Q A;  1R0K A;  2O7G A;  4KP7 A;  1H3L A;  3UER A;  1SC5 A;  4FLO A;  3CZE A;  3ZI0 A;  2JD0 A;  1JGI A;  1K5H A;  4Y6S A;  2C82 A;  2Y1F A;  3WQQ A;  2WPG A;  4OOE A;  2Y1D A;  3IIE A;  3RAS A;  1MVY A;  2JD1 A;  3T0Y A;  3ZHZ A;  1MW0 A;  1JG9 A;  1MW1 A;  2Y1E A;  1JVS A;  4CXF A;  4FLS A;  5JAZ A;  4ZQG A;  1MW3 A;  1R0L A;  1Q0L A;  4Y67 A;  3R0I A;  3CZL A;  4ZN6 A;  5JO0 A;  5JMP A;  4A03 A;  2JCV A;  4OOF A;  3AU8 A;  5JMW A;  5JNL A;  3UCQ A;  4FLQ A;  3CZK A;  1RP3 A;  4FLR A;  1S46 A;  2EGH A;  3ANM A;  5DUL A;  3ZHX A;  1ONP A;  4LUP A;  2JD2 A;  1MW2 A;  3ANN A;  3CZG A;  1T1R A;  4GAE A;  5JBI A;  1ONO A;  4AIC A;  2JCY A;  1ZS2 A;  3WQS B;  1OR7 A;  3UEQ A;  5JC1 A;  4Y6R A;  1T1S A;  2JCX A;  3ANL A;  4AYS A; 
#chains in the Genus database with same CATH topology
 4ZQH A;  4L2L A;  3FH8 A;  4GAA A;  4QPE A;  1G5A A;  3VVL A;  3WQR A;  3FTW A;  3FU3 A;  3FUI A;  4ZQF A;  3FUL A;  3A14 A;  4XND A;  4XMZ A;  2XQ0 A;  4QUO A;  3FUK A;  2A7O A;  2MAO A;  3ZHY A;  2WZF A;  4ZX6 A;  4ZQE A;  3CHR A;  4AR9 A;  2Y1C A;  4ZX5 A;  2Y1G A;  4RCV A;  3CHO A;  4QIR A;  3CHP A;  3A06 A;  4JND A;  4XO3 A;  3CIA A;  4NQW A;  3FTZ A;  4Y6P A;  2MAP A;  3AU9 A;  3B2X A;  4XMU A;  3FU0 A;  1ONN A;  4R5T A;  2ZXG A;  3AUA A;  3FTV A;  1Q0H A;  1Q0Q A;  1R0K A;  3JSZ A;  2O7G A;  1H3L A;  4KP7 A;  3UER A;  1SC5 A;  2FFL A;  4FLO A;  4AR1 A;  4K5P A;  3CZE A;  3ZI0 A;  4XN2 A;  4PVB A;  4ZW3 A;  4XNB A;  3CHQ A;  4R7L A;  5EV7 A;  3RC3 A;  4AR8 A;  2JD0 A;  1SQM A;  4XN5 A;  1JGI A;  4Q4E A;  5HNF A;  3KED A;  1K5H A;  4ZW6 A;  4XMV A;  2RJI A;  3B37 A;  3FHE A;  4XO4 A;  2QVW A;  2C82 A;  2Y1F A;  3FUD A;  2WPG A;  4Y6S A;  3WQQ A;  4OOE A;  2Y1D A;  3B3B A;  3IIE A;  4R5X A;  3RAS A;  1MVY A;  3FTU A;  4XN4 A;  2JD1 A;  5FWQ A;  3QJX A;  4XN1 A;  3HW2 A;  3T0Y A;  4ARF A;  3ZHZ A;  2R72 A;  4ZQT A;  1MW0 A;  1JG9 A;  4PW4 A;  4K5O A;  4XMX A;  1MW1 A;  2Y1E A;  2VLA A;  5HNH A;  1JVS A;  4CXF A;  3PUU A;  4DPR A;  4XMT A;  4FLS A;  3FUF A;  4RVB A;  4MKT A;  3B34 A;  4ZW8 A;  5AEN A;  2QJ1 A;  3FTS A;  5JAZ A;  4ZQG A;  3FH7 A;  1MW3 A;  1R0L A;  3U9W A;  1Q0L A;  1X3W A;  2R70 A;  2WZG A;  3B7S A;  2DQ6 A;  3VVM A;  3CHS A;  4QHP A;  4Y67 A;  3R0I A;  3CZL A;  1X3Z A;  3Q43 A;  1HS6 A;  4ZN6 A;  4MS6 A;  5JO0 A;  4XO5 A;  4XMW A;  5DLL A;  5JMP A;  4ZX3 A;  4K5L A;  4A03 A;  4K5M A;  2JCV A;  4OOF A;  4QME A;  3AU8 A;  5JMW A;  2HPT A;  5JNL A;  2XPZ A;  3FUE A;  3UCQ A;  3B7T A;  4FLQ A;  3CZK A;  3FUH A;  3B7U X;  1GW6 A;  5BPP A;  4XNA A;  2GTQ A;  3B7R L;  2JV7 A;  4XN8 A;  2B61 A;  3FU6 A;  4Q4I A;  1RP3 A;  3FH5 A;  4FLR A;  1S46 A;  3FTX A;  2EGH A;  2C5Z A;  4XN9 A;  4K5N A;  2VJ8 A;  3ANM A;  3FUJ A;  5DUL A;  4RSY A;  1ONP A;  3ZHX A;  2XPY A;  3CXB A;  3JT1 A;  4LUP A;  4PU2 A;  4BKX A;  2JD2 A;  4XN7 A;  3FTY A;  1MW2 A;  3ANN A;  2DQM A;  3CZG A;  1T1R A;  2PUS A;  3FUM A;  2PGG A;  4X2U A;  2PL5 A;  2R59 A;  4FCA A;  3Q44 A;  4GAE A;  5JBI A;  1ONO A;  3EBG A;  2HPO A;  4ZW7 A;  4AIC A;  3T8V A;  4R5V A;  2JCY A;  4J3B A;  1ZS2 A;  3EBI A;  3RC8 A;  3FUN A;  3WQS B;  1OR7 A;  3UEQ A;  3FU5 A;  5DYF A;  5JC1 A;  4Y6R A;  5HLT A;  1T1S A;  4ZX4 A;  1SG7 A;  2JCX A;  1H19 A;  3EBH A;  4ZW5 A;  3ANL A;  4AYS A;  3B2P A; 
#chains in the Genus database with same CATH homology
 4ZQH A;  4L2L A;  3FH8 A;  4GAA A;  4QPE A;  1G5A A;  3VVL A;  3WQR A;  3FTW A;  3FU3 A;  3FUI A;  4ZQF A;  3FUL A;  3A14 A;  4XND A;  4XMZ A;  2XQ0 A;  4QUO A;  3FUK A;  2A7O A;  2MAO A;  3ZHY A;  2WZF A;  4ZX6 A;  4ZQE A;  3CHR A;  4AR9 A;  2Y1C A;  4ZX5 A;  2Y1G A;  4RCV A;  3CHO A;  4QIR A;  3CHP A;  3A06 A;  4JND A;  4XO3 A;  3CIA A;  4NQW A;  3FTZ A;  4Y6P A;  2MAP A;  3AU9 A;  3B2X A;  4XMU A;  3FU0 A;  1ONN A;  4R5T A;  2ZXG A;  3AUA A;  3FTV A;  1Q0H A;  1Q0Q A;  1R0K A;  3JSZ A;  2O7G A;  1H3L A;  4KP7 A;  3UER A;  1SC5 A;  2FFL A;  4FLO A;  4AR1 A;  4K5P A;  3CZE A;  3ZI0 A;  4XN2 A;  4PVB A;  4ZW3 A;  4XNB A;  3CHQ A;  4R7L A;  5EV7 A;  3RC3 A;  4AR8 A;  2JD0 A;  1SQM A;  4XN5 A;  1JGI A;  4Q4E A;  5HNF A;  3KED A;  1K5H A;  4ZW6 A;  4XMV A;  2RJI A;  3B37 A;  3FHE A;  4XO4 A;  2QVW A;  2C82 A;  2Y1F A;  3FUD A;  2WPG A;  4Y6S A;  3WQQ A;  4OOE A;  2Y1D A;  3B3B A;  3IIE A;  4R5X A;  3RAS A;  1MVY A;  3FTU A;  4XN4 A;  2JD1 A;  5FWQ A;  3QJX A;  4XN1 A;  3T0Y A;  4ARF A;  3ZHZ A;  2R72 A;  4ZQT A;  1MW0 A;  1JG9 A;  4PW4 A;  4K5O A;  4XMX A;  1MW1 A;  2Y1E A;  2VLA A;  5HNH A;  1JVS A;  4CXF A;  3PUU A;  4DPR A;  4XMT A;  4FLS A;  3FUF A;  4RVB A;  4MKT A;  3B34 A;  4ZW8 A;  5AEN A;  2QJ1 A;  3FTS A;  5JAZ A;  4ZQG A;  3FH7 A;  1MW3 A;  1R0L A;  3U9W A;  1Q0L A;  1X3W A;  2R70 A;  2WZG A;  3B7S A;  2DQ6 A;  3VVM A;  3CHS A;  4QHP A;  4Y67 A;  3R0I A;  3CZL A;  1X3Z A;  3Q43 A;  1HS6 A;  4ZN6 A;  4MS6 A;  5JO0 A;  4XO5 A;  4XMW A;  5DLL A;  5JMP A;  4ZX3 A;  4K5L A;  4A03 A;  4K5M A;  2JCV A;  4OOF A;  4QME A;  3AU8 A;  5JMW A;  2HPT A;  5JNL A;  2XPZ A;  3FUE A;  3UCQ A;  3B7T A;  4FLQ A;  3CZK A;  3FUH A;  3B7U X;  1GW6 A;  5BPP A;  4XNA A;  2GTQ A;  3B7R L;  2JV7 A;  4XN8 A;  2B61 A;  3FU6 A;  4Q4I A;  1RP3 A;  3FH5 A;  4FLR A;  1S46 A;  3FTX A;  2EGH A;  2C5Z A;  4XN9 A;  4K5N A;  2VJ8 A;  3ANM A;  3FUJ A;  5DUL A;  4RSY A;  1ONP A;  3ZHX A;  2XPY A;  3JT1 A;  4LUP A;  4PU2 A;  4BKX A;  2JD2 A;  4XN7 A;  3FTY A;  1MW2 A;  3ANN A;  2DQM A;  3CZG A;  1T1R A;  2PUS A;  3FUM A;  2PGG A;  4X2U A;  2PL5 A;  2R59 A;  4FCA A;  3Q44 A;  4GAE A;  5JBI A;  1ONO A;  3EBG A;  2HPO A;  4ZW7 A;  4AIC A;  3T8V A;  4R5V A;  2JCY A;  4J3B A;  1ZS2 A;  3EBI A;  3RC8 A;  3FUN A;  3WQS B;  1OR7 A;  3UEQ A;  3FU5 A;  5DYF A;  5JC1 A;  4Y6R A;  5HLT A;  1T1S A;  4ZX4 A;  1SG7 A;  2JCX A;  1H19 A;  3EBH A;  4ZW5 A;  3ANL A;  4AYS A;  3B2P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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