4MDUA

Crystal structure of apo-annexin (sm)1
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
357
structure length
357
Chain Sequence
SEFGITRSLIHSFDPHGKHYRPTIKPTTGFSASADAERLHRSMKGPGTNELAIINILARRTNYERQEICQSYKSLYKQDLKDDLKSDTSGDFRKVLCQLIVDTPYMLAKSLYYAMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPILQLKAIPDKGVNSIINHELAEADAKDLYASGAGRVGTSERRITRVICNRTPYQLYLTSEIYFKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALMRLLITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMGEIY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Annexin
publication title Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Metal binding protein
total genus 138
structure length 357
sequence length 357
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mduA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mduA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mduA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mduA03
1W3WA 1M9IA 2HYUA 2HYWA 1YIIA 2IE7A 1AOWA 2IE6A 1ALAA 1AXNA 2Q4CA 1AVCA 1W7BA 1I4AA 1AEIA 1HVGA 1XJLA 2XO2A 1A8BA 1DK5A 1MCXA 1AIIA 1AVRA 1ANNA 1HVDA 1HVEA 1N41A 4HREA 2RANA 4EVHA 1HAKA 1BCWA 1BCZA 1N42A 2H0LA 1HVFA 4X9PA 1DM5A 1G5NA 1A8AA 2HYVA 4MDUA 4EVFA 2ZHIA 1BCYA 1BC0A 1HM6A 2IICA 1N44A 1BO9A 1SAVA 2II2A 2H0MA 1BC1A 1YCNA 2XO3A 2ZHJA 1N00A 3BRXA 2H0KA 1AVHA 1ANXA 2ZOCA 1YJ0A 1W45A 1BC3A 4MDVA 1ANWA
chains in the Genus database with same CATH superfamily
4JK1X 3ANYA 4D7QA 2Q4CA 1AVCA 2VXGA 1RE0B 1R8QE 2R0DA 4EVHA 4HREA 1HAKA 3USWA 1BCZA 1N42A 3ABSA 2ZHIA 1BCYA 2R09A 2IICA 1SAVA 2II2A 2H0MA 1BC1A 2XO3A 4KN7X 1UPTB 2QEZA 3AO0A 2HYUA 4JMOA 2HYWA 4FHRB 2IE7A 2IE6A 4Q2SA 1ALAA 1AXNA 1AEIA 1HVGA 1BC9A 1MCXA 1XSZA 3HJLA 1N41A 4Z21A 1R4AE 1HVFA 1DM5A 2HYVA 4JWLA 1HM6A 3TW5A 4A4PA 1BO9A 2ZHJA 1YGMA 2H0KA 2ZOCA 2H0LA 1W45A 4MDVA 1W3WA 3SWVA 4FQ0C 4L5MA 3LTLA 1LKVX 1YIIA 3ABOA 1AOWA 2HSNA 4OIYA 1I4AA 1R8SE 1XJLA 2K6XA 4JXHA 1AIIA 4JMIA 1AVRA 1ANNA 1HVDA 4C0AA 4KN4X 1BCWA 1A8AA 1BC0A 1YCNA 3ABQA 3BRXA 1AVHA 1ANXA 3L8NA 1KU1A 1DK5A 1G5NA 1BC3A 4KMUX 4D7RA 3AJCA 1M9IA 3USYA 1QC7A 1W7BA 3SOHB 2XO2A 1A8BA 3ABRA 1R8ME 1HVEA 2RANA 4C7PA 1XT0B 1C1KA 4X9PA 2OY9A 4EVFA 4MDUA 1N44A 1S9DE 1N00A 1YJ0A 1PBVA 1Q8DA 1ANWA
chains in the Genus database with same CATH topology
1W3WA 1M9IA 2HYUA 2HYWA 1YIIA 2IE7A 1AOWA 2IE6A 1ALAA 1AXNA 2Q4CA 1AVCA 1W7BA 1I4AA 1AEIA 1HVGA 1XJLA 2XO2A 1A8BA 1DK5A 1MCXA 1AIIA 1AVRA 1ANNA 1HVDA 1HVEA 1N41A 4HREA 2RANA 4EVHA 1HAKA 1BCWA 1BCZA 1N42A 2H0LA 1HVFA 4X9PA 1DM5A 1G5NA 1A8AA 2HYVA 4MDUA 4EVFA 2ZHIA 1BCYA 1BC0A 1HM6A 2IICA 1N44A 1BO9A 1SAVA 2II2A 2H0MA 1BC1A 1YCNA 2XO3A 2ZHJA 1N00A 3BRXA 2H0KA 1AVHA 1ANXA 2ZOCA 1YJ0A 1W45A 1BC3A 4MDVA 1ANWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W3W A;  1M9I A;  2HYU A;  2HYW A;  1YII A;  2IE7 A;  1AOW A;  2IE6 A;  1ALA A;  1AXN A;  2Q4C A;  1AVC A;  1W7B A;  1I4A A;  1AEI A;  1HVG A;  1XJL A;  2XO2 A;  1A8B A;  1DK5 A;  1MCX A;  1AII A;  1AVR A;  1ANN A;  1HVD A;  1HVE A;  1N41 A;  4HRE A;  2RAN A;  4EVH A;  1HAK A;  1BCW A;  1BCZ A;  1N42 A;  2H0L A;  1HVF A;  4X9P A;  1DM5 A;  1G5N A;  1A8A A;  2HYV A;  4MDU A;  4EVF A;  2ZHI A;  1BCY A;  1BC0 A;  1HM6 A;  2IIC A;  1N44 A;  1BO9 A;  1SAV A;  2II2 A;  2H0M A;  1BC1 A;  1YCN A;  2XO3 A;  2ZHJ A;  1N00 A;  3BRX A;  2H0K A;  1AVH A;  1ANX A;  2ZOC A;  1YJ0 A;  1W45 A;  1BC3 A;  4MDV A;  1ANW A; 
#chains in the Genus database with same CATH topology
 4JK1 X;  3ANY A;  4D7Q A;  2Q4C A;  1AVC A;  2VXG A;  1RE0 B;  1R8Q E;  2R0D A;  4EVH A;  4HRE A;  1HAK A;  3USW A;  1BCZ A;  1N42 A;  3ABS A;  2ZHI A;  1BCY A;  2R09 A;  2IIC A;  1SAV A;  2II2 A;  2H0M A;  1BC1 A;  2XO3 A;  4KN7 X;  1UPT B;  2QEZ A;  3AO0 A;  2HYU A;  4JMO A;  2HYW A;  4FHR B;  2IE7 A;  2IE6 A;  4Q2S A;  1ALA A;  1AXN A;  1AEI A;  1HVG A;  1BC9 A;  1MCX A;  1XSZ A;  3HJL A;  1N41 A;  4Z21 A;  1R4A E;  1HVF A;  1DM5 A;  2HYV A;  4JWL A;  1HM6 A;  3TW5 A;  4A4P A;  1BO9 A;  2ZHJ A;  1YGM A;  2H0K A;  2ZOC A;  2H0L A;  1W45 A;  4MDV A;  1W3W A;  3SWV A;  4FQ0 C;  4L5M A;  3LTL A;  1LKV X;  1YII A;  3ABO A;  1AOW A;  2HSN A;  4OIY A;  1I4A A;  1R8S E;  1XJL A;  2K6X A;  4JXH A;  1AII A;  4JMI A;  1AVR A;  1ANN A;  1HVD A;  4C0A A;  4KN4 X;  1BCW A;  1A8A A;  1BC0 A;  1YCN A;  3ABQ A;  3BRX A;  1AVH A;  1ANX A;  3L8N A;  1KU1 A;  1DK5 A;  1G5N A;  1BC3 A;  4KMU X;  4D7R A;  3AJC A;  1M9I A;  3USY A;  1QC7 A;  1W7B A;  3SOH B;  2XO2 A;  1A8B A;  3ABR A;  1R8M E;  1HVE A;  2RAN A;  4C7P A;  1XT0 B;  1C1K A;  4X9P A;  2OY9 A;  4EVF A;  4MDU A;  1N44 A;  1S9D E;  1N00 A;  1YJ0 A;  1PBV A;  1Q8D A;  1ANW A; 
#chains in the Genus database with same CATH homology
 1W3W A;  1M9I A;  2HYU A;  2HYW A;  1YII A;  2IE7 A;  1AOW A;  2IE6 A;  1ALA A;  1AXN A;  2Q4C A;  1AVC A;  1W7B A;  1I4A A;  1AEI A;  1HVG A;  1XJL A;  2XO2 A;  1A8B A;  1DK5 A;  1MCX A;  1AII A;  1AVR A;  1ANN A;  1HVD A;  1HVE A;  1N41 A;  4HRE A;  2RAN A;  4EVH A;  1HAK A;  1BCW A;  1BCZ A;  1N42 A;  2H0L A;  1HVF A;  4X9P A;  1DM5 A;  1G5N A;  1A8A A;  2HYV A;  4MDU A;  4EVF A;  2ZHI A;  1BCY A;  1BC0 A;  1HM6 A;  2IIC A;  1N44 A;  1BO9 A;  1SAV A;  2II2 A;  2H0M A;  1BC1 A;  1YCN A;  2XO3 A;  2ZHJ A;  1N00 A;  3BRX A;  2H0K A;  1AVH A;  1ANX A;  2ZOC A;  1YJ0 A;  1W45 A;  1BC3 A;  4MDV A;  1ANW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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