4MDVA

Crystal structure of calcium-bound annexin (sm)1
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
359
structure length
351
Chain Sequence
ISEFGITRSLIHSFDPHGKHYRPTIKPTTGFSASADAERLHRSMKGPGTNELAIINILARRTNYERQEICQSYKSLYKQDLKDDLKSDTSGDFRKVLCQLIVDTPYMLAKSLYYAMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPILQLKAIPDKGVNSIINHELAEADAKDLYASERRITRVICNRTPYQLYLTSEIYFKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALMRLLITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMGEIYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Annexin
publication title Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Metal binding protein
total genus 136
structure length 351
sequence length 359
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA03
2IICA 4MDVA 1HVDA 1N00A 2ZHJA 1DM5A 2IE7A 2ZOCA 2XO2A 4EVFA 4EVHA 1N42A 1W45A 1AVHA 1A8BA 1SAVA 2H0MA 1MCXA 2HYUA 1HM6A 1BCWA 1HVGA 2XO3A 1HAKA 1AXNA 4MDUA 1BCZA 1A8AA 1N41A 2H0LA 1N44A 1YIIA 1HVFA 1ANNA 1AOWA 3BRXA 2RANA 4X9PA 1BC0A 2HYVA 1DK5A 1ALAA 1G5NA 1W3WA 1XJLA 2H0KA 1YJ0A 1AVRA 2HYWA 1ANXA 1AVCA 1AIIA 1HVEA 1M9IA 4HREA 1ANWA 1W7BA 1BC1A 1BCYA 2II2A 1AEIA 1BO9A 2IE6A 1YCNA 2ZHIA 2Q4CA 1BC3A 1I4AA
chains in the Genus database with same CATH superfamily
4MDVA 1Q8DA 2ZHJA 4EVFA 3ABRA 2HSNA 4D7RA 1AXNA 4X9PA 2RANA 1ALAA 2H0KA 4KN4X 1YJ0A 4L5MA 2HYWA 1ANXA 1AVCA 4Z21A 1BC1A 2II2A 1AEIA 4JXHA 3ABQA 2Q4CA 1BC3A 1MCXA 1N00A 1QC7A 1UPTB 2IE7A 3HJLA 2XO2A 1N42A 4JK1X 1W45A 2H0MA 4A4PA 2HYUA 4KN7X 3ABOA 1BCWA 3ANYA 2XO3A 4MDUA 1KU1A 4JMOA 1HVFA 1AOWA 1DK5A 4OIYA 1XJLA 1AVRA 1AIIA 3SWVA 1R8ME 4JMIA 1BO9A 1YCNA 2ZHIA 1I4AA 1HVDA 2ZOCA 1AVHA 3USYA 1A8BA 1HVGA 2QEZA 1R4AE 1R8SE 4Q2SA 1N41A 2K6XA 3BRXA 1PBVA 4FHRB 3ABSA 1W3WA 4D7QA 1HVEA 1BC9A 4KMUX 1LKVX 4C7PA 1YGMA 3AJCA 2R09A 2OY9A 2IICA 1DM5A 4EVHA 1XSZA 1R8QE 1SAVA 1XT0B 1HM6A 1C1KA 1HAKA 3SOHB 3L8NA 1BCZA 1A8AA 4JWLA 2H0LA 1N44A 1YIIA 3USWA 1ANNA 3LTLA 1BC0A 2HYVA 1G5NA 1RE0B 3AO0A 4C0AA 2VXGA 2R0DA 1M9IA 4HREA 1ANWA 1W7BA 1BCYA 4FQ0C 2IE6A 1S9DE 3TW5A
chains in the Genus database with same CATH topology
2IICA 4MDVA 1HVDA 1N00A 2ZHJA 1DM5A 2IE7A 2ZOCA 2XO2A 4EVFA 4EVHA 1N42A 1W45A 1AVHA 1A8BA 1SAVA 2H0MA 1MCXA 2HYUA 1HM6A 1BCWA 1HVGA 2XO3A 1HAKA 1AXNA 4MDUA 1BCZA 1A8AA 1N41A 2H0LA 1N44A 1YIIA 1HVFA 1ANNA 1AOWA 3BRXA 2RANA 4X9PA 1BC0A 2HYVA 1DK5A 1ALAA 1G5NA 1W3WA 1XJLA 2H0KA 1YJ0A 1AVRA 2HYWA 1ANXA 1AVCA 1AIIA 1HVEA 1M9IA 4HREA 1ANWA 1W7BA 1BC1A 1BCYA 2II2A 1AEIA 1BO9A 2IE6A 1YCNA 2ZHIA 2Q4CA 1BC3A 1I4AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IIC A;  4MDV A;  1HVD A;  1N00 A;  2ZHJ A;  1DM5 A;  2IE7 A;  2ZOC A;  2XO2 A;  4EVF A;  4EVH A;  1N42 A;  1W45 A;  1AVH A;  1A8B A;  1SAV A;  2H0M A;  1MCX A;  2HYU A;  1HM6 A;  1BCW A;  1HVG A;  2XO3 A;  1HAK A;  1AXN A;  4MDU A;  1BCZ A;  1A8A A;  1N41 A;  2H0L A;  1N44 A;  1YII A;  1HVF A;  1ANN A;  1AOW A;  3BRX A;  2RAN A;  4X9P A;  1BC0 A;  2HYV A;  1DK5 A;  1ALA A;  1G5N A;  1W3W A;  1XJL A;  2H0K A;  1YJ0 A;  1AVR A;  2HYW A;  1ANX A;  1AVC A;  1AII A;  1HVE A;  1M9I A;  4HRE A;  1ANW A;  1W7B A;  1BC1 A;  1BCY A;  2II2 A;  1AEI A;  1BO9 A;  2IE6 A;  1YCN A;  2ZHI A;  2Q4C A;  1BC3 A;  1I4A A; 
#chains in the Genus database with same CATH topology
 4MDV A;  1Q8D A;  2ZHJ A;  4EVF A;  3ABR A;  2HSN A;  4D7R A;  1AXN A;  4X9P A;  2RAN A;  1ALA A;  2H0K A;  4KN4 X;  1YJ0 A;  4L5M A;  2HYW A;  1ANX A;  1AVC A;  4Z21 A;  1BC1 A;  2II2 A;  1AEI A;  4JXH A;  3ABQ A;  2Q4C A;  1BC3 A;  1MCX A;  1N00 A;  1QC7 A;  1UPT B;  2IE7 A;  3HJL A;  2XO2 A;  1N42 A;  4JK1 X;  1W45 A;  2H0M A;  4A4P A;  2HYU A;  4KN7 X;  3ABO A;  1BCW A;  3ANY A;  2XO3 A;  4MDU A;  1KU1 A;  4JMO A;  1HVF A;  1AOW A;  1DK5 A;  4OIY A;  1XJL A;  1AVR A;  1AII A;  3SWV A;  1R8M E;  4JMI A;  1BO9 A;  1YCN A;  2ZHI A;  1I4A A;  1HVD A;  2ZOC A;  1AVH A;  3USY A;  1A8B A;  1HVG A;  2QEZ A;  1R4A E;  1R8S E;  4Q2S A;  1N41 A;  2K6X A;  3BRX A;  1PBV A;  4FHR B;  3ABS A;  1W3W A;  4D7Q A;  1HVE A;  1BC9 A;  4KMU X;  1LKV X;  4C7P A;  1YGM A;  3AJC A;  2R09 A;  2OY9 A;  2IIC A;  1DM5 A;  4EVH A;  1XSZ A;  1R8Q E;  1SAV A;  1XT0 B;  1HM6 A;  1C1K A;  1HAK A;  3SOH B;  3L8N A;  1BCZ A;  1A8A A;  4JWL A;  2H0L A;  1N44 A;  1YII A;  3USW A;  1ANN A;  3LTL A;  1BC0 A;  2HYV A;  1G5N A;  1RE0 B;  3AO0 A;  4C0A A;  2VXG A;  2R0D A;  1M9I A;  4HRE A;  1ANW A;  1W7B A;  1BCY A;  4FQ0 C;  2IE6 A;  1S9D E;  3TW5 A; 
#chains in the Genus database with same CATH homology
 2IIC A;  4MDV A;  1HVD A;  1N00 A;  2ZHJ A;  1DM5 A;  2IE7 A;  2ZOC A;  2XO2 A;  4EVF A;  4EVH A;  1N42 A;  1W45 A;  1AVH A;  1A8B A;  1SAV A;  2H0M A;  1MCX A;  2HYU A;  1HM6 A;  1BCW A;  1HVG A;  2XO3 A;  1HAK A;  1AXN A;  4MDU A;  1BCZ A;  1A8A A;  1N41 A;  2H0L A;  1N44 A;  1YII A;  1HVF A;  1ANN A;  1AOW A;  3BRX A;  2RAN A;  4X9P A;  1BC0 A;  2HYV A;  1DK5 A;  1ALA A;  1G5N A;  1W3W A;  1XJL A;  2H0K A;  1YJ0 A;  1AVR A;  2HYW A;  1ANX A;  1AVC A;  1AII A;  1HVE A;  1M9I A;  4HRE A;  1ANW A;  1W7B A;  1BC1 A;  1BCY A;  2II2 A;  1AEI A;  1BO9 A;  2IE6 A;  1YCN A;  2ZHI A;  2Q4C A;  1BC3 A;  1I4A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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